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Anthony L. DeFranco - Publications

Molecular & Cell Biology University of California, Berkeley, Berkeley, CA 
 Microbiology and Immunology University of California, San Francisco, San Francisco, CA 
Immunology, Cell Biology

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Proekt I, Miller CN, Jeanne M, Fasano KJ, Moon JJ, Lowell CA, Gould DB, Anderson MS, DeFranco AL. LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity. The Journal of Clinical Investigation. PMID 27571405 DOI: 10.1172/Jci84440  1
2015 Beck-Engeser GB, Winkelmann R, Wheeler ML, Shansab M, Yu P, Wünsche S, Walchhütter A, Metzner M, Vettermann C, Eilat D, DeFranco A, Jäck HM, Wabl M. APOBEC3 enzymes restrict marginal zone B cells. European Journal of Immunology. 45: 695-704. PMID 25501566 DOI: 10.1002/Eji.201445218  1
2014 Rookhuizen DC, DeFranco AL. Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses. Proceedings of the National Academy of Sciences of the United States of America. 111: E3224-33. PMID 25053813 DOI: 10.1073/Pnas.1323985111  1
2014 Yu M, Zhou H, Zhao J, Xiao N, Roychowdhury S, Schmitt D, Hu B, Ransohoff RM, Harding CV, Hise AG, Hazen SL, DeFranco AL, Fox PL, Morton RE, Dicorleto PE, et al. MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. The Journal of Experimental Medicine. 211: 887-907. PMID 24752299 DOI: 10.1084/Jem.20131314  1
2014 Hua Z, Gross AJ, Lamagna C, Ramos-Hernández N, Scapini P, Ji M, Shao H, Lowell CA, Hou B, DeFranco AL. Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 192: 875-85. PMID 24379120 DOI: 10.4049/Jimmunol.1300683  1
2014 Lamagna C, Hu Y, DeFranco AL, Lowell CA. B cell-specific loss of Lyn kinase leads to autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 192: 919-28. PMID 24376269 DOI: 10.4049/Jimmunol.1301979  1
2014 Yu M, Zhou H, Zhao J, Xiao N, Roychowdhury S, Schmitt D, Hu B, Ransohoff RM, Harding CV, Hise AG, Hazen SL, DeFranco AL, Fox PL, Morton RE, Dicorleto PE, et al. Correction to MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases [J. Exp. Med., 211, 5, (2014) 887-907] Journal of Experimental Medicine. 211: 1003. DOI: 10.1084/Jem.2013131404222014C  1
2013 Lamagna C, Scapini P, van Ziffle JA, DeFranco AL, Lowell CA. Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation. Proceedings of the National Academy of Sciences of the United States of America. 110: E3311-20. PMID 23940344 DOI: 10.1073/Pnas.1300617110  1
2013 Han D, Walsh MC, Cejas PJ, Dang NN, Kim YF, Kim J, Charrier-Hisamuddin L, Chau L, Zhang Q, Bittinger K, Bushman FD, Turka LA, Shen H, Reizis B, Defranco AL, et al. Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance. Immunity. 38: 1211-22. PMID 23791643 DOI: 10.1016/J.Immuni.2013.05.012  1
2013 Callahan JA, Hammer GE, Agelides A, Duong BH, Oshima S, North J, Advincula R, Shifrin N, Truong HA, Paw J, Barrera J, DeFranco A, Rosenblum MD, Malynn BA, Ma A. Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 535-9. PMID 23785118 DOI: 10.4049/Jimmunol.1203335  1
2013 Raetz M, Hwang SH, Wilhelm CL, Kirkland D, Benson A, Sturge CR, Mirpuri J, Vaishnava S, Hou B, Defranco AL, Gilpin CJ, Hooper LV, Yarovinsky F. Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells. Nature Immunology. 14: 136-42. PMID 23263554 DOI: 10.1038/Ni.2508  1
2012 Kim CC, Nelson CS, Wilson EB, Hou B, DeFranco AL, DeRisi JL. Splenic red pulp macrophages produce type I interferons as early sentinels of malaria infection but are dispensable for control. Plos One. 7: e48126. PMID 23144737 DOI: 10.1371/Journal.Pone.0048126  1
2012 Wheeler ML, Defranco AL. Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation. Journal of Immunology (Baltimore, Md. : 1950). 189: 4405-16. PMID 23024271 DOI: 10.4049/Jimmunol.1201433  1
2012 DeFranco AL, Rookhuizen DC, Hou B. Contribution of Toll-like receptor signaling to germinal center antibody responses. Immunological Reviews. 247: 64-72. PMID 22500832 DOI: 10.1111/J.1600-065X.2012.01115.X  1
2012 Thompson AL, Johnson BT, Sempowski GD, Gunn MD, Hou B, DeFranco AL, Staats HF. Maximal adjuvant activity of nasally delivered IL-1α requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 188: 2834-46. PMID 22345651 DOI: 10.4049/Jimmunol.1100254  1
2012 Kirkland D, Benson A, Mirpuri J, Pifer R, Hou B, DeFranco AL, Yarovinsky F. B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage. Immunity. 36: 228-38. PMID 22306056 DOI: 10.1016/J.Immuni.2011.11.019  1
2012 Shahaf G, Gross AJ, Sternberg-Simon M, Kaplan D, DeFranco AL, Mehr R. Lyn deficiency affects B-cell maturation as well as survival. European Journal of Immunology. 42: 511-21. PMID 22057631 DOI: 10.1002/Eji.201141940  1
2011 Hammer GE, Turer EE, Taylor KE, Fang CJ, Advincula R, Oshima S, Barrera J, Huang EJ, Hou B, Malynn BA, Reizis B, DeFranco A, Criswell LA, Nakamura MC, Ma A. Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. Nature Immunology. 12: 1184-93. PMID 22019834 DOI: 10.1038/Ni.2135  1
2011 Gross AJ, Proekt I, DeFranco AL. Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells. European Journal of Immunology. 41: 3645-55. PMID 21928281 DOI: 10.1002/Eji.201141708  1
2011 Scapini P, Lamagna C, Hu Y, Lee K, Tang Q, DeFranco AL, Lowell CA. B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 108: E823-32. PMID 21911371 DOI: 10.1073/Pnas.1107913108  1
2011 Ismail AS, Severson KM, Vaishnava S, Behrendt CL, Yu X, Benjamin JL, Ruhn KA, Hou B, DeFranco AL, Yarovinsky F, Hooper LV. Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface. Proceedings of the National Academy of Sciences of the United States of America. 108: 8743-8. PMID 21555560 DOI: 10.1073/Pnas.1019574108  1
2011 Rahman AH, Zhang R, Blosser CD, Hou B, Defranco AL, Maltzman JS, Wherry EJ, Turka LA. Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88. Blood. 117: 3123-30. PMID 21233312 DOI: 10.1182/Blood-2010-11-318485  1
2011 Hou B, Benson A, Kuzmich L, DeFranco AL, Yarovinsky F. Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors. Proceedings of the National Academy of Sciences of the United States of America. 108: 278-83. PMID 21173242 DOI: 10.1073/Pnas.1011549108  1
2010 Scapini P, Hu Y, Chu CL, Migone TS, Defranco AL, Cassatella MA, Lowell CA. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. The Journal of Experimental Medicine. 207: 1757-73. PMID 20624892 DOI: 10.1084/Jem.20100086  1
2010 Mamchak AA, Thien CB, Dagger SA, Lyandres J, Jiang S, Langdon WY, DeFranco AL. Unaltered negative selection and Treg development of self-reactive thymocytes in TCR transgenic Fyn-deficient mice. European Journal of Immunology. 40: 539-47. PMID 19904769 DOI: 10.1002/Eji.200939645  1
2009 Gross AJ, Lyandres JR, Panigrahi AK, Prak ET, DeFranco AL. Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance. Journal of Immunology (Baltimore, Md. : 1950). 182: 5382-92. PMID 19380785 DOI: 10.4049/Jimmunol.0803941  1
2008 DeFranco AL. "Dangerous crystals". Immunity. 29: 670-1. PMID 19006690 DOI: 10.1016/j.immuni.2008.10.005  1
2008 Mamchak AA, Sullivan BM, Hou B, Lee LM, Gilden JK, Krummel MF, Locksley RM, DeFranco AL. Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 5374-85. PMID 18832694 DOI: 10.4049/Jimmunol.181.8.5374  1
2008 Hou B, Reizis B, DeFranco AL. Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity. 29: 272-82. PMID 18656388 DOI: 10.1016/J.Immuni.2008.05.016  1
2007 Gupta N, DeFranco AL. Lipid rafts and B cell signaling. Seminars in Cell & Developmental Biology. 18: 616-26. PMID 17719248 DOI: 10.1016/J.Semcdb.2007.07.009  1
2006 Gupta N, Wollscheid B, Watts JD, Scheer B, Aebersold R, DeFranco AL. Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics. Nature Immunology. 7: 625-33. PMID 16648854 DOI: 10.1038/Ni1337  1
2005 Nishiya T, Kajita E, Miwa S, Defranco AL. TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements. The Journal of Biological Chemistry. 280: 37107-17. PMID 16105838 DOI: 10.1074/Jbc.M504951200  1
2005 Tian MT, Gonzalez G, Scheer B, DeFranco AL. Bcl10 can promote survival of antigen-stimulated B lymphocytes. Blood. 106: 2105-12. PMID 15878976 DOI: 10.1182/Blood-2004-04-1248  1
2004 Nishiya T, DeFranco AL. Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors. The Journal of Biological Chemistry. 279: 19008-17. PMID 14976215 DOI: 10.1074/Jbc.M311618200  1
2003 Gupta N, DeFranco AL. Visualizing lipid raft dynamics and early signaling events during antigen receptor-mediated B-lymphocyte activation. Molecular Biology of the Cell. 14: 432-44. PMID 12589045 DOI: 10.1091/Mbc.02-05-0078  1
2003 Yu CC, Mamchak AA, DeFranco AL. Signaling mutations and autoimmunity. Current Directions in Autoimmunity. 6: 61-88. PMID 12408047 DOI: 10.1159/000066856  1
2002 Ohashi PS, DeFranco AL. Making and breaking tolerance. Current Opinion in Immunology. 14: 744-59. PMID 12413525 DOI: 10.1016/S0952-7915(02)00406-5  1
2001 DeFranco AL. Vav and the B cell signalosome Nature Immunology. 2: 482-484. PMID 11376331 DOI: 10.1038/88669  1
2001 Tian MT, Chou CHG, DeFranco AL. Apoptosis induced by the antigen receptor and Fas in a variant of the immature B cell line WEHI-231 and in splenic immature B cells International Immunology. 13: 581-592. PMID 11282997 DOI: 10.1093/Intimm/13.4.581  1
2001 Richards JD, Davé SH, Chou CHG, Mamchak AA, DeFranco AL. Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen Journal of Immunology. 166: 3855-3864. PMID 11238629 DOI: 10.4049/Jimmunol.166.6.3855  1
2001 Yu CCK, Yen TSB, Lowell CA, DeFranco AL. Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn Current Biology. 11: 34-38. PMID 11166177 DOI: 10.1016/S0960-9822(00)00024-5  1
2000 DeFranco AL. B-cell activation 2000 Immunological Reviews. 176: 5-9. PMID 11043763  1
2000 Fujimoto M, Fujimoto Y, Poe JC, Jansen PJ, Lowell CA, DeFranco AL, Tedder TF. CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification Immunity. 13: 47-57. PMID 10933394 DOI: 10.1016/S1074-7613(00)00007-8  1
2000 Weinstein SL, Finn AJ, Davé SH, Meng F, Lowell CA, Sanghera JS, DeFranco AL. Phosphatidylinositol 3-kinase and mTOR mediate lipopolysaccharide-stimulated nitric oxide production in macrophages via interferon-beta. Journal of Leukocyte Biology. 67: 405-14. PMID 10733102 DOI: 10.1002/Jlb.67.3.405  1
2000 Fitzer-Attas CJ, Lowry M, Crowley MT, Finn AJ, Meng F, DeFranco AL, Lowel CA. Fcγ receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn Journal of Experimental Medicine. 191: 669-681. DOI: 10.1084/jem.191.4.669  1
1999 Harmer SL, DeFranco AL. The Src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with Shc and Grb2 in antigen receptor-stimulated B lymphocytes Journal of Biological Chemistry. 274: 12183-12191. PMID 10207047 DOI: 10.1074/Jbc.274.17.12183  1
1999 MacKichan ML, DeFranco AL. Role of ceramide in lipopolysaccharide (LPS)-induced signaling. LPS increases ceramide rather than acting as a structural homolog Journal of Biological Chemistry. 274: 1767-1775. PMID 9880559 DOI: 10.1074/Jbc.274.3.1767  1
1998 DeFranco AL, Chan VWF, Lowell CA. Positive and negative roles of the tyrosine kinase Lyn in B cell function Seminars in Immunology. 10: 299-307. PMID 9695186 DOI: 10.1006/Smim.1998.0122  1
1998 Chan VWF, Lowell CA, DeFranco AL. Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes Current Biology. 8: 545-553. PMID 9601638 DOI: 10.1016/S0960-9822(98)70223-4  1
1998 DeFranco AL, Crowley MT, Finn A, Hambleton J, Weinstein SL. The role of tyrosine kinases and map kinases in LPS-induced signaling Progress in Clinical and Biological Research. 397: 119-136. PMID 9575553  1
1998 DeFranco AL, Weiss A. Lymphocyte activation and effector functions. Turning lymphocytes on and off Current Opinion in Immunology. 10: 243-244. DOI: 10.1016/S0952-7915(98)80160-X  1
1997 Crowley MT, Costello PS, Fitzer-Attas CJ, Turner M, Meng F, Lowell C, Tybulewicz VL, DeFranco AL. A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. The Journal of Experimental Medicine. 186: 1027-39. PMID 9314552 DOI: 10.1084/Jem.186.7.1027  1
1997 Chan VWF, Meng F, Soriano P, DeFranco AL, Lowell CA. Characterization of the B lymphocyte populations in lyn-deficient mice and the role of lyn in signal initiation and down-regulation Immunity. 7: 69-81. PMID 9252121 DOI: 10.1016/S1074-7613(00)80511-7  1
1997 DeFranco AL. The complexity of signaling pathways activated by the BCR Current Opinion in Immunology. 9: 296-308. PMID 9203421 DOI: 10.1016/S0952-7915(97)80074-X  1
1997 Harmer SL, DeFranco AL. Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes Molecular and Cellular Biology. 17: 4087-4095. PMID 9199344 DOI: 10.1128/Mcb.17.7.4087  1
1996 DeFranco AL. B-cell co-receptors: The two-headed antigen Current Biology. 6: 548-550. PMID 8805272 DOI: 10.1016/S0960-9822(02)00539-0  1
1996 Roth PE, DeFranco AL. Receptor tails unlock developmental checkpoints for B lymphocytes Science. 272: 1752-1754. PMID 8650572 DOI: 10.1126/Science.272.5269.1752  1
1996 Richards JD, Gold MR, Hourihanell SL, DeFranco AL, Matsuuchi L. Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase Journal of Biological Chemistry. 271: 6458-6466. PMID 8626447 DOI: 10.1074/Jbc.271.11.6458  1
1996 Horne MC, Roth PE, DeFranco AL. Assembly of the truncated immunoglobulin heavy chain Dμ into antigen receptor-like complexes in pre-B cells but not in B cells Immunity. 4: 145-158. PMID 8624805 DOI: 10.1016/S1074-7613(00)80679-2  1
1996 Hambleton J, Weinstein SL, Lem L, DeFranco AL. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proceedings of the National Academy of Sciences of the United States of America. 93: 2774-8. PMID 8610116 DOI: 10.1073/Pnas.93.7.2774  1
1996 Crowley MT, Harmer SL, DeFranco AL. Activation-induced association of a 145-kDa tyrosine-phosphorylated protein with Shc and Syk in B lymphocytes and macrophages Journal of Biological Chemistry. 271: 1145-1152. PMID 8557643 DOI: 10.1074/Jbc.271.2.1145  1
1996 Matsuuchi L, Richards J, Gold MR, Defranco AL, Hourihane SL. The syk tyrosine kinase is essential for b cell antigen receptor signaling Faseb Journal. 10.  1
1995 DeFranco AL, Hambleton J, McMahon M, Weinstein SL. Examination of the role of MAP kinase in the response of macrophages to lipopolysaccharide Progress in Clinical and Biological Research. 392: 407-420. PMID 8524948  1
1995 Hambleton J, McMahon M, DeFranco AL. Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events Journal of Experimental Medicine. 182: 147-154. PMID 7790814 DOI: 10.1084/Jem.182.1.147  1
1995 DeFranco AL, Law DA. Tyrosine phosphatases and the antibody response Science. 268: 263-264. PMID 7716518 DOI: 10.1126/Science.7716518  1
1995 Roth PE, DeFranco AL. Lymphocyte Development: Intrinsic checkpoints for lineage progression Current Biology. 5: 349-352. PMID 7627545 DOI: 10.1016/S0960-9822(95)00069-8  1
1995 DeFranco AL. Transmembrane signaling by antigen receptors of B and T lymphocytes Current Opinion in Cell Biology. 7: 163-175. PMID 7612267 DOI: 10.1016/0955-0674(95)80024-7  1
1995 DeFranco AL, Richards JD, Blum JH, Stevens TL, Law DA, Chan VWF, Datta SK, Foy SP, Hourihane SL, Gold MR, Matsuuchi L. Signal transduction by the B-cell antigen receptor Annals of the New York Academy of Sciences. 766: 195-201. PMID 7486656 DOI: 10.1111/J.1749-6632.1995.Tb26662.X  1
1995 DeFranco AL, Coffman RL. Lymphocyte activation and effector functions Editorial overview Current Opinion in Immunology. 7: 303-305. DOI: 10.1016/0952-7915(95)80102-2  1
1994 Gold MR, DeFranco AL. Biochemistry of B lymphocyte activation Advances in Immunology. 55: 221-295. PMID 8304234 DOI: 10.1016/S0065-2776(08)60511-8  1
1994 Stevens TL, Blum JH, Foy SP, Matsuuchi L, DeFranco AL. A mutation of the μ transmembrane that disrupts endoplasmic reticulum retention: Effects on association with accessory proteins and signal transduction Journal of Immunology. 152: 4397-4406. PMID 8157960  1
1994 DeFranco AL, Blum JH, Stevens TL, Law DA, Chan VWF, Foy SP, Datta SK, Matsuuchi L. Structure and function of the B-cell antigen receptor Chemical Immunology. 59: 156-172. PMID 7945925  1
1994 DeFranco AL. Signaling pathways activated by protein tyrosine phosphorylation in lymphocytes Current Opinion in Immunology. 6: 364-371. PMID 7917103 DOI: 10.1016/0952-7915(94)90114-7  1
1994 DeFranco AL, Mittelstadt PR, Blum JH, Stevens TL, Law DA, Chan - VWF, Foy SP, Datta SK, Matsuuchi L. Mechanism of B cell antigen receptor function: Transmembrane signaling and triggering of apoptosis Advances in Experimental Medicine and Biology. 365: 9-22. PMID 7887317 DOI: 10.1007/978-1-4899-0987-9_2  1
1993 Gold MR, Crowley MT, Martin GA, McCormick F, DeFranco AL. Targets of B Lymphocyte Antigen Receptor Signal Transduction Include the p21ras GTPase-Activating Protein (GAP) and Two GAP-Associated Proteins 1 Journal of Immunology. 150: 377-386. PMID 8419471  1
1993 Mittelstadt PR, DeFranco AL. Induction of early response genes by cross-linking membrane Ig on B lymphocytes Journal of Immunology. 150: 4822-4832. PMID 8388422  1
1993 Shapiro AM, Schlissel MS, Baltimore D, Defranco AL. Stimulation of κ light-chain gene rearrangement by the immunoglobulin μ heavy chain in a pre-B-cell line Molecular and Cellular Biology. 13: 5679-5690. PMID 8355709 DOI: 10.1128/Mcb.13.9.5679  1
1993 DeFranco AL. Structure and function of the B cell antigen receptor Annual Review of Cell Biology. 9: 377-410. PMID 8280466 DOI: 10.1146/Annurev.Cb.09.110193.002113  1
1993 Blum JH, Stevens TL, DeFranco AL. Role of the μ immunoglobulin heavy chain transmembrane and cytoplasmic domains in B cell antigen receptor expression and signal transduction Journal of Biological Chemistry. 268: 27236-27245. PMID 8262964  1
1993 Weinstein SL, June CH, DeFranco AL. Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14 Journal of Immunology. 151: 3829-3838. PMID 7690817  1
1993 DeFranco AL. Signaling the insulin receptor way Current Biology. 3: 713-715. DOI: 10.1016/0960-9822(93)90077-2  1
1993 Law DA, Chan VWF, Datta SK, DeFranco AL. B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn Current Biology. 3: 645-657. DOI: 10.1016/0960-9822(93)90062-S  1
1992 Hempel WM, Schatzman RC, DeFranco AL. Tyrosine phosphorylation of phospholipase C-gamma 2 upon cross-linking of membrane Ig on murine B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 148: 3021-7. PMID 1578127  1
1992 DeFranco AL. Hidden lymphocytes Nature. 357: 14-15. PMID 1574123  1
1992 Law DA, Gold MR, DeFranco AL. Examination of B lymphoid cell lines for membrane immunoglobulin-stimulated tyrosine phosphorylation and src-family tyrosine kinase mRNA expression Molecular Immunology. 29: 917-926. PMID 1378935 DOI: 10.1016/0161-5890(92)90130-P  1
1992 Matsuuchi L, Gold MR, Travis A, Grosschedl R, DeFranco AL, Kelly RB. The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line. Proceedings of the National Academy of Sciences of the United States of America. 89: 3404-8. PMID 1373499 DOI: 10.1073/Pnas.89.8.3404  1
1992 Gold MR, Chan VWF, Turck CW, DeFranco AL. Membrane Ig cross-linking regulates phosphatidylinositol 3-kinase in B lymphocytes Journal of Immunology. 148: 2012-2022. PMID 1372019  1
1992 DeFranco AL. Tyrosine phosphorylation and the mechanism of signal transduction by the B-lymphocyte antigen receptor European Journal of Biochemistry. 210: 381-388. PMID 1281096 DOI: 10.1111/J.1432-1033.1992.Tb17432.X  1
1992 DeFranco AL. bcl-2 to the rescue Current Biology. 2: 95-97. DOI: 10.1016/0960-9822(92)90227-2  1
1992 DeFranco AL. How do B-1 cells originate? Nature. 357: 14.  1
1991 Hempel WM, DeFranco AL. Expression of phospholipase C isozymes by murine B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 146: 3713-20. PMID 2033248  1
1991 Page DM, Gold MR, Fahey KA, Matsuuehi L, DeFranco AL. Mutational analysis of antigen receptor regulation of B lymphocyte growth: Evidence for involvement of the phosphoinositide signaling pathway Journal of Biological Chemistry. 266: 5563-5574. PMID 1848555  1
1991 Gold MR, Gajewski TF, DeFranco AL. Regulation of anti-immunoglobulin-induced B lymphoma growth arrest by transforming growth factor β1 and dexamethasone International Immunology. 3: 1091-1098. PMID 1760404 DOI: 10.1093/Intimm/3.11.1091  1
1991 DeFranco AL. All about B cells Cancer Cells. 3: 450-453. PMID 1760246  1
1991 DeFranco AL. Immunosuppressants at work Nature. 352: 754-755. PMID 1715515 DOI: 10.1038/352754A0  1
1991 Weinstein SL, Gold MR, DeFranco AL. Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages Proceedings of the National Academy of Sciences of the United States of America. 88: 4148-4152. PMID 1709735 DOI: 10.1073/Pnas.88.10.4148  1
1991 Gold MR, Matsuuchi L, Kelly RB, DeFranco AL. Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking. Proceedings of the National Academy of Sciences of the United States of America. 88: 3436-40. PMID 1707541 DOI: 10.1073/Pnas.88.8.3436  1
1991 DeFranco AL. Between B cells and T cells Nature. 351: 603-604. PMID 1675766 DOI: 10.1038/351603A0  1
1990 Page DM, DeFranco AL. Antigen Receptor-Induced Cell Cycle Arrest in WEHI-231 B Lymphoma Cells Depends on the Duration of Signaling before the G1 Phase Restriction Point Molecular and Cellular Biology. 10: 3003-3012. PMID 2342467 DOI: 10.1128/Mcb.10.6.3003  1
1990 Gold MR, Law DA, DeFranco AL. Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor Nature. 345: 810-813. PMID 1694265 DOI: 10.1038/345810A0  1
1989 DeFranco AL. Tolerance: A second mechanism Nature. 342: 340-341. PMID 2586604 DOI: 10.1038/342340A0  1
1989 DeFranco AL, Page DM, Blum JH, Gold MR. Signal transduction by the antigen receptor of B lymphocytes Cold Spring Harbor Symposia On Quantitative Biology. 54: 733-740. PMID 2561805 DOI: 10.1101/Sqb.1989.054.01.086  1
1989 DeFranco AL, Gold MR. Signal transduction via the B cell antigen receptor: involvement of a G protein and regulation of signaling Advances in Experimental Medicine and Biology. 254: 101-112. PMID 2554695 DOI: 10.1007/978-1-4757-5803-0_13  1
1988 DeFranco AL. Fate of self-reactive B cells Nature. 334: 652-653. PMID 3261840 DOI: 10.1038/334652A0  1
1988 DeFranco AL. Cell-cell interactions in the antibody response Nature. 334: 199-200. PMID 2969459 DOI: 10.1038/334199A0  1
1988 Page DM, DeFranco AL. Role of phosphoinositide-derived second messengers in mediating anti-IgM-induced growth arrest of WEHI-231 B lymphoma cells Journal of Immunology. 140: 3717-3726. PMID 2836499  1
1987 DeFranco AL. Transmembrane signaling reactions generated in B cells in response to anti-IgM or lipopolysaccharide Advances in Experimental Medicine and Biology. 213: 189-193. PMID 3498297 DOI: 10.1007/978-1-4684-5323-2_18  1
1987 Fahey KA, DeFranco AL. Cross-linking membrane IgM induces production of inositol trisphosphate and inositol tetrakisphosphate in WEHI-231 B lymphoma cells Journal of Immunology. 138: 3935-3942. PMID 3035017  1
1987 Gold MR, DeFranco AL. Phorbol esters and dioctanoylglycerol block anti-IgM-stimulated phosphoinositide hydrolysis in the murine B cell lymphoma WEHI-231 Journal of Immunology. 138: 868-876. PMID 3027166  1
1987 DeFranco AL. Molecular aspects of B-lymphocyte activation Annual Review of Cell Biology. 3: 143-178. PMID 2961351 DOI: 10.1146/Annurev.Cb.03.110187.001043  1
1987 Gold MR, Jakway JP, DeFranco AL. Involvement of a guanine nucleotide-binding component in membrane IgM-stimulated phosphoinositide breakdown Journal of Immunology. 139: 3604-3613. PMID 2824610  1
1987 DeFranco AL, Gold MR, Jakway JP. B-lymphocyte signal transduction in response to anti-immunoglobulin and bacterial lipopolysaccharide Immunological Reviews. 161-176.  1
1986 Jakway JP, Usinger WR, Gold MR, Mishell RI, DeFranco AL. Growth regulation of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products Journal of Immunology. 137: 2225-2231. PMID 3489760  1
1986 Jakway JP, DeFranco AL. Pertussis toxin inhibition of B cell and macrophage responses to bacterial lipopolysaccharide Science. 234: 743-746. PMID 3095921 DOI: 10.1126/Science.3095921  1
1986 LaBaer J, Tsien RY, Fahey KA, DeFranco AL. Stimulation of the antigen receptor on WEHI-231 B lymphoma cells results in a voltage-independent increase in cytoplasmic calcium Journal of Immunology. 137: 1836-1844. PMID 2427581  1
1985 Ashwell JD, DeFranco AL, Paul WE, Schwartz RH. Can resting B cells present antigen to T cells? Federation Proceedings. 44: 2475-2479. PMID 3886434  1
1985 DeFranco AL, Raveche ES, Paul WE. Separate control of B lymphocyte early activation and proliferation in response to anti-IgM antibodies Journal of Immunology. 135: 87-94. PMID 3873499  1
1985 Jakway JP, DeFranco AL. Development of monoclonal antibodies which may recognize the receptor for lipopolysaccharide on mouse B cells Federation Proceedings. 44.  1
1985 DeFranco AL, LaBaer J, Fahey KA, Tsien RY. Crosslinkage of membrane IgM causes an increase in cytoplasmic calcium via phosphoinositide hydrolysis Federation Proceedings. 44.  1
1984 Ashwell JD, DeFranco AL, Paul WE, Schwartz RH. Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation Journal of Experimental Medicine. 159: 881-905. PMID 6607969 DOI: 10.1084/Jem.159.3.881  1
1984 DeFranco AL. Growth regulation of a B-cell lymphoma via the antigen receptor Current Topics in Microbiology and Immunology. 113: 92-95. PMID 6332723 DOI: 10.1007/978-3-642-69860-6_17  1
1984 DeFranco AL, Ashwell JD, Schwartz RH, Paul WE. Polyclonal stimulation of resting B lymphocytes by antigen-specific T lymphocytes Journal of Experimental Medicine. 159: 861-880. PMID 6199453 DOI: 10.1084/Jem.159.3.861  1
1984 Ashwell JD, DeFranco AL, Paul WE, Schwartz RH. Antigen presentation by resting B cells Federation Proceedings. 43.  1
1982 DeFranco AL, Kung JT, Paul WE. Regulation of growth and proliferation in B cell subpopulations Immunological Reviews. 161-182. PMID 6806172 DOI: 10.1111/J.1600-065X.1982.Tb00423.X  1
1982 Defranco AL, Raveche ES, Asofsky R, Paul WE. Frequency of B lymphocytes responsive to anti-immunoglobulin Journal of Experimental Medicine. 155: 1523-1536. PMID 6802927 DOI: 10.1084/Jem.155.5.1523  1
1982 DeFranco AL, Koshland DE. Construction and behavior of strains with mutations in two chemotaxis genes. Journal of Bacteriology. 150: 1297-301. PMID 6281242  1
1982 Raveche ES, Steinberg AD, DeFranco AL, Tjio JH. Cell cycle analysis of lymphocyte activation in normal and autoimmune strains of mice Journal of Immunology. 129: 1219-1226. PMID 6125541  1
1981 DeFranco AL, Koshland DE. Molecular cloning of chemotaxis genes and overproduction of gene products in the bacterial sensing system Journal of Bacteriology. 147: 390-400. PMID 7021528 DOI: 10.1128/Jb.147.2.390-400.1981  1
1980 DeFranco AL, Koshland DE. Multiple methylation in processing of sensory signals during bacterial chemotaxis Proceedings of the National Academy of Sciences of the United States of America. 77: 2429-2433. PMID 6446711 DOI: 10.1073/Pnas.77.5.2429  1
1979 DeFranco AL, Parkinson JS, Koshland DE. Functional homology of chemotaxis genes in Escherichia coli and Salmonella typhimurium Journal of Bacteriology. 139: 107-114. PMID 378950 DOI: 10.1128/Jb.139.1.107-114.1979  1
1978 Khan S, Macnab RM, DeFranco AL, Koshland DE. Inversion of a behavioral response in bacterial chemotaxis: explanation at the molecular level Proceedings of the National Academy of Sciences of the United States of America. 75: 4150-4154. PMID 360210 DOI: 10.1073/Pnas.75.9.4150  1
1977 Springer TA, Mann DL, DeFranco AL, Strominger JL. Detergent solubilization, purification, and separation of specificities of HLA antigens from a cultured human lymphoblastoid line, RPMI 4265. The Journal of Biological Chemistry. 252: 4682-93. PMID 68955  1
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