Kirsten C. Sadler - Publications

Affiliations: 
Developmental and Stem Cell Biology (DSCB) Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Human Development, Cell Biology, Genetics

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Chernyavskaya Y, Mudbhary R, Tokarz D, Jacob V, Gopinath S, Zhang C, Sun X, Wang S, Magnani E, Madakashira BP, Yoder JA, Hoshida Y, Sadler KC. Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (Cambridge, England). PMID 28698226 DOI: 10.1242/dev.147629  1
2017 DeRossi C, Shtraizent N, Nayar S, Sachidanandam R, Katz LS, Prince A, Koh AP, Vincek A, Hadas Y, Hoshida Y, Scott DK, Eliyahu E, Freeze HH, Sadler KC, Chu J. MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect. Elife. 6. PMID 28644127 DOI: 10.7554/eLife.22477  0.4
2016 DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, Baryshnikova A, Milev MP, Stanga D, Kadakia D, Gao N, Chu J, Freeze HH, Lehrman MA, Sacher M, ... Sadler KC, et al. trappc11 is required for protein glycosylation in zebrafish and humans. Molecular Biology of the Cell. PMID 26912795 DOI: 10.1091/mbc.E15-08-0557  1
2016 Kent B, Magnani E, Walsh MJ, Sadler KC. UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development. Developmental Biology. PMID 26851214 DOI: 10.1016/j.ydbio.2016.01.036  1
2015 Goessling W, Sadler KC. Zebrafish: An Important Tool for Liver Disease Research. Gastroenterology. 149: 1361-77. PMID 26319012 DOI: 10.1053/j.gastro.2015.08.034  1
2015 Jacob V, Chernyavskaya Y, Chen X, Tan PS, Kent B, Hoshida Y, Sadler KC. DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos. Development (Cambridge, England). 142: 510-21. PMID 25564650 DOI: 10.1242/dev.115980  1
2014 Vacaru AM, Di Narzo AF, Howarth DL, Tsedensodnom O, Imrie D, Cinaroglu A, Amin S, Hao K, Sadler KC. Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish. Disease Models & Mechanisms. 7: 823-35. PMID 24973751 DOI: 10.1242/dmm.014472  1
2014 Howarth DL, Lindtner C, Vacaru AM, Sachidanandam R, Tsedensodnom O, Vasilkova T, Buettner C, Sadler KC. Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish. Plos Genetics. 10: e1004335. PMID 24874946 DOI: 10.1371/journal.pgen.1004335  1
2014 Dhandapany PS, Razzaque MA, Muthusami U, Kunnoth S, Edwards JJ, Mulero-Navarro S, Riess I, Pardo S, Sheng J, Rani DS, Rani B, Govindaraj P, Flex E, Yokota T, Furutani M, ... ... Sadler KC, et al. RAF1 mutations in childhood-onset dilated cardiomyopathy. Nature Genetics. 46: 635-9. PMID 24777450 DOI: 10.1038/ng.2963  1
2014 Mudbhary R, Hoshida Y, Chernyavskaya Y, Jacob V, Villanueva A, Fiel MI, Chen X, Kojima K, Thung S, Bronson RT, Lachenmayer A, Revill K, Alsinet C, Sachidanandam R, Desai A, ... ... Sadler KC, et al. UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma. Cancer Cell. 25: 196-209. PMID 24486181 DOI: 10.1016/j.ccr.2014.01.003  1
2014 Vacaru AM, Unlu G, Spitzner M, Mione M, Knapik EW, Sadler KC. In vivo cell biology in zebrafish - providing insights into vertebrate development and disease. Journal of Cell Science. 127: 485-95. PMID 24481493 DOI: 10.1242/jcs.140194  1
2014 Jacob V, Sadler KC. MKKing the most of liver regeneration: an in vivo screen identifies the MKK4 pathway as a suppressor of regeneration. Hepatology (Baltimore, Md.). 59: 1201-3. PMID 24123204 DOI: 10.1002/hep.26757  1
2013 Tsedensodnom O, Vacaru AM, Howarth DL, Yin C, Sadler KC. Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease. Disease Models & Mechanisms. 6: 1213-26. PMID 23798569 DOI: 10.1242/dmm.012195  1
2013 Sadler KC, Rawls JF, Farber SA. Getting the inside tract: new frontiers in zebrafish digestive system biology. Zebrafish. 10: 129-31. PMID 23738756 DOI: 10.1089/zeb.2013.1500  1
2013 Tsedensodnom O, Sadler KC. ROS: redux and paradox in fatty liver disease. Hepatology (Baltimore, Md.). 58: 1210-2. PMID 23703804 DOI: 10.1002/hep.26497  1
2013 Howarth DL, Yin C, Yeh K, Sadler KC. Defining hepatic dysfunction parameters in two models of fatty liver disease in zebrafish larvae. Zebrafish. 10: 199-210. PMID 23697887 DOI: 10.1089/zeb.2012.0821  1
2013 Chu J, Mir A, Gao N, Rosa S, Monson C, Sharma V, Steet R, Freeze HH, Lehrman MA, Sadler KC. A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation. Disease Models & Mechanisms. 6: 95-105. PMID 22899857 DOI: 10.1242/dmm.010116  1
2013 Heath JK, Langenau D, Sadler KC, White R. Models of transparency Scientist. 27.  1
2012 Cline A, Gao N, Flanagan-Steet H, Sharma V, Rosa S, Sonon R, Azadi P, Sadler KC, Freeze HH, Lehrman MA, Steet R. A zebrafish model of PMM2-CDG reveals altered neurogenesis and a substrate-accumulation mechanism for N-linked glycosylation deficiency. Molecular Biology of the Cell. 23: 4175-87. PMID 22956764 DOI: 10.1091/mbc.E12-05-0411  1
2012 Imrie D, Sadler KC. Stress management: How the unfolded protein response impacts fatty liver disease. Journal of Hepatology. 57: 1147-51. PMID 22732510 DOI: 10.1016/j.jhep.2012.06.018  1
2012 Gerhart SV, Eble DM, Burger RM, Oline SN, Vacaru A, Sadler KC, Jefferis R, Iovine MK. The Cx43-like connexin protein Cx40.8 is differentially localized during fin ontogeny and fin regeneration. Plos One. 7: e31364. PMID 22347467 DOI: 10.1371/journal.pone.0031364  1
2012 Chu J, Loughlin EA, Gaur NA, SenBanerjee S, Jacob V, Monson C, Kent B, Oranu A, Ding Y, Ukomadu C, Sadler KC. UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis. Molecular Biology of the Cell. 23: 59-70. PMID 22072796 DOI: 10.1091/mbc.E11-06-0487  1
2012 Howarth DL, Vacaru AM, Tsedensodnom O, Mormone E, Nieto N, Costantini LM, Snapp EL, Sadler KC. Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes. Alcoholism, Clinical and Experimental Research. 36: 14-23. PMID 21790674 DOI: 10.1111/j.1530-0277.2011.01602.x  1
2011 Mudbhary R, Sadler KC. Epigenetics, development, and cancer: zebrafish make their mark.. Birth Defects Research. Part C, Embryo Today : Reviews. 93: 194-203. PMID 21671358 DOI: 10.1002/bdrc.20207  1
2011 Cinaroglu A, Gao C, Imrie D, Sadler KC. Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish. Hepatology (Baltimore, Md.). 54: 495-508. PMID 21538441 DOI: 10.1002/hep.24396  1
2011 Thakur PC, Stuckenholz C, Rivera MR, Davison JM, Yao JK, Amsterdam A, Sadler KC, Bahary N. Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish. Hepatology (Baltimore, Md.). 54: 452-62. PMID 21488074 DOI: 10.1002/hep.24349  1
2011 Howarth DL, Passeri M, Sadler KC. Drinks like a fish: using zebrafish to understand alcoholic liver disease. Alcoholism, Clinical and Experimental Research. 35: 826-9. PMID 21284674 DOI: 10.1111/j.1530-0277.2010.01407.x  1
2011 Tien AL, Senbanerjee S, Kulkarni A, Mudbhary R, Goudreau B, Ganesan S, Sadler KC, Ukomadu C. UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis. The Biochemical Journal. 435: 175-85. PMID 21214517 DOI: 10.1042/BJ20100840  1
2010 Imrie D, Sadler KC. White adipose tissue development in zebrafish is regulated by both developmental time and fish size. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 3013-23. PMID 20925116 DOI: 10.1002/dvdy.22443  1
2010 Monson CA, Sadler KC. Inbreeding depression and outbreeding depression are evident in wild-type zebrafish lines. Zebrafish. 7: 189-97. PMID 20438386 DOI: 10.1089/zeb.2009.0648  1
2010 Zhao X, Monson C, Gao C, Gouon-Evans V, Matsumoto N, Sadler KC, Friedman SL. Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells. Developmental Biology. 344: 79-93. PMID 20430021 DOI: 10.1016/j.ydbio.2010.04.018  1
2009 Chu J, Sadler KC. New school in liver development: lessons from zebrafish. Hepatology (Baltimore, Md.). 50: 1656-63. PMID 19693947 DOI: 10.1002/hep.23157  1
2009 Eichenbaum JW, Cinaroglu A, Eichenbaum KD, Sadler KC. A zebrafish retinal graded photochemical stress model. Journal of Pharmacological and Toxicological Methods. 59: 121-7. PMID 19269339 DOI: 10.1016/j.vascn.2009.02.006  1
2009 Passeri MJ, Cinaroglu A, Gao C, Sadler KC. Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation. Hepatology (Baltimore, Md.). 49: 443-52. PMID 19127516 DOI: 10.1002/hep.22667  1
2008 Sakaguchi TF, Sadler KC, Crosnier C, Stainier DY. Endothelial signals modulate hepatocyte apicobasal polarization in zebrafish. Current Biology : Cb. 18: 1565-71. PMID 18951027 DOI: 10.1016/j.cub.2008.08.065  1
2008 Toyoshima Y, Monson C, Duan C, Wu Y, Gao C, Yakar S, Sadler KC, LeRoith D. The role of insulin receptor signaling in zebrafish embryogenesis. Endocrinology. 149: 5996-6005. PMID 18687786 DOI: 10.1210/en.2008-0329  1
2007 Sadler KC, Krahn KN, Gaur NA, Ukomadu C. Liver growth in the embryo and during liver regeneration in zebrafish requires the cell cycle regulator, uhrf1. Proceedings of the National Academy of Sciences of the United States of America. 104: 1570-5. PMID 17242348 DOI: 10.1073/pnas.0610774104  1
2005 Sadler KC, Amsterdam A, Soroka C, Boyer J, Hopkins N. A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease. Development (Cambridge, England). 132: 3561-72. PMID 16000385 DOI: 10.1242/dev.01918  1
2005 Hamarato?lu F, Ero?lu A, Toner M, Sadler KC. Cryopreservation of starfish oocytes. Cryobiology. 50: 38-47. PMID 15710368 DOI: 10.1016/j.cryobiol.2004.09.008  1
2004 Amsterdam A, Sadler KC, Lai K, Farrington S, Bronson RT, Lees JA, Hopkins N. Many ribosomal protein genes are cancer genes in zebrafish. Plos Biology. 2: E139. PMID 15138505 DOI: 10.1371/journal.pbio.0020139  1
2004 Sadler KC, Yüce O, Hamaratoglu F, Vergé V, Peaucellier G, Picard A. MAP kinases regulate unfertilized egg apoptosis and fertilization suppresses death via Ca2+ signaling. Molecular Reproduction and Development. 67: 366-83. PMID 14735498 DOI: 10.1002/mrd.20023  1
2002 Köseolu M, Erolu A, Toner M, Sadler KC. Starfish oocytes form intracellular ice at unusually high temperatures Cryobiology. 43: 248-259. PMID 11888218 DOI: 10.1006/cryo.2001.2348  1
2001 Yuce O, Sadler KC. Postmeiotic unfertilized starfish eggs die by apoptosis Developmental Biology. 237: 29-44. PMID 11518503 DOI: 10.1006/dbio.2001.0361  1
2000 Sadler KC, Do Carmo Avides M. Orchestrating cell division Trends in Cell Biology. 10: 447-450. PMID 11202984 DOI: 10.1016/S0962-8924(00)01820-1  1
1998 Sadler KC, Ruderman JV. Components of the signaling pathway linking the 1-methyladenine receptor to MPF activation and maturation in starfish oocytes. Developmental Biology. 197: 25-38. PMID 9578616 DOI: 10.1006/dbio.1998.8869  1
1992 Sadler KC, Bevins CL, Kaltenbach JC. Localization of xenopsin and xenopsin precursor fragment immunoreactivities in the skin and gastrointestinal tract of Xenopus laevis Cell &Amp; Tissue Research. 270: 257-263. PMID 1451171 DOI: 10.1007/BF00328011  1
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