Mary E. Abood - Publications

Cell Biology Temple University, Philadelphia, PA, United States 
Molecular Biology, Pharmacology, Biochemistry

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Garai S, Leo LM, Szczesniak AM, Hurst DP, Schaffer PC, Zagzoog A, Black T, Deschamps JR, Miess E, Schulz S, Janero DR, Straiker A, Pertwee RG, Abood ME, Kelly MEM, et al. Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy. Journal of Medicinal Chemistry. PMID 33826336 DOI: 10.1021/acs.jmedchem.1c00040  0.4
2020 Morales P, Lago-Fernandez A, Hurst DP, Sotudeh N, Brailoiu E, Reggio PH, Abood ME, Jagerovic N. Therapeutic Exploitation of GPR18: Beyond the Cannabinoids? Journal of Medicinal Chemistry. PMID 32914978 DOI: 10.1021/Acs.Jmedchem.0C00926  0.4
2019 Garai S, Kulkarni PM, Schaffer PC, Leo L, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, et al. Application of Fluorine- And Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of CB1 Receptor Positive Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31756109 DOI: 10.1021/Acs.Jmedchem.9B01142  0.4
2017 Console-Bram L, Ciuciu SM, Zhao P, Zipkin RE, Brailoiu E, Abood ME. N-arachidonoyl glycine, another endogenous agonist of GPR55. Biochemical and Biophysical Research Communications. PMID 28698140 DOI: 10.1016/J.Bbrc.2017.07.038  0.8
2017 Fakhouri L, Cook CD, Al-Huniti MH, Console-Bram LM, Hurst DP, Spano MBS, Nasrallah DJ, Caron MG, Barak LS, Reggio PH, Abood ME, Croatt MP. Design, synthesis and biological evaluation of GPR55 agonists. Bioorganic & Medicinal Chemistry. PMID 28673732 DOI: 10.1016/J.Bmc.2017.06.016  0.4
2016 Lingerfelt MA, Zhao P, Sharir HP, Hurst DP, Reggio PH, Abood ME. Identification of crucial amino acid residues involved in agonist signaling at the GPR55 receptor. Biochemistry. PMID 28005346 DOI: 10.1021/Acs.Biochem.6B01013  0.4
2016 Abdalhameed MM, Zhao P, Hurst DP, Reggio PH, Abood ME, Croatt MP. Structure-activity relationships of benzothiazole GPR35 antagonists. Bioorganic & Medicinal Chemistry Letters. PMID 27989666 DOI: 10.1016/J.Bmcl.2016.12.012  0.4
2016 Meza-Aviña ME, Lingerfelt MA, Console-Bram LM, Gamage TF, Sharir H, Gettys KE, Hurst DP, Kotsikorou E, Shore DM, Caron MG, Rao N, Barak LS, Abood ME, Reggio PH, Croatt MP. Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones. Bioorganic & Medicinal Chemistry Letters. PMID 26916440 DOI: 10.1016/J.Bmcl.2016.02.030  0.4
2016 Abood ME. Allosteric Modulators: A Side Door. Journal of Medicinal Chemistry. 59: 42-3. PMID 26645411 DOI: 10.1021/Acs.Jmedchem.5B01824  0.8
2015 Barr JL, Deliu E, Brailoiu GC, Zhao P, Yan G, Abood ME, Unterwald EM, Brailoiu E. Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways. Cell Calcium. 58: 196-207. PMID 26077147 DOI: 10.1016/J.Ceca.2015.05.001  0.8
2015 Deliu E, Sperow M, Console-Bram L, Carter RL, Tilley DG, Kalamarides DJ, Kirby LG, Brailoiu GC, Brailoiu E, Benamar K, Abood ME. The Lysophosphatidylinositol Receptor GPR55 Modulates Pain Perception in the Periaqueductal Gray. Molecular Pharmacology. 88: 265-72. PMID 25972448 DOI: 10.1124/Mol.115.099333  0.8
2015 Giannopoulos PF, Chu J, Sperow M, Li JG, Yu WH, Kirby LG, Abood M, Praticò D. Pharmacologic Inhibition of 5-Lipoxygenase Improves Memory, Rescues Synaptic Dysfunction, and Ameliorates Tau Pathology in a Transgenic Model of Tauopathy. Biological Psychiatry. PMID 25802082 DOI: 10.1016/J.Biopsych.2015.01.015  0.8
2015 Palma J, Abood ME, Benamar K. HIV-gp120 and physical dependence to buprenorphine Drug and Alcohol Dependence. 150: 175-178. PMID 25765484 DOI: 10.1016/J.Drugalcdep.2015.02.021  0.8
2015 Altmann JB, Yan G, Meeks JF, Abood ME, Brailoiu E, Brailoiu GC. G protein-coupled estrogen receptor-mediated effects on cytosolic calcium and nanomechanics in brain microvascular endothelial cells. Journal of Neurochemistry. 133: 629-39. PMID 25703621 DOI: 10.1111/Jnc.13066  0.8
2014 Rahman T, Cai X, Brailoiu GC, Abood ME, Brailoiu E, Patel S. Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels. Science Signaling. 7: ra109. PMID 25406377 DOI: 10.1126/scisignal.2005450  0.8
2014 Lucchesi V, Hurst DP, Shore DM, Bertini S, Ehrmann BM, Allarà M, Lawrence L, Ligresti A, Minutolo F, Saccomanni G, Sharir H, Macchia M, Di Marzo V, Abood ME, Reggio PH, et al. CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. Journal of Medicinal Chemistry. 57: 8777-91. PMID 25272206 DOI: 10.1021/Jm500807E  0.8
2014 Lin-Moshier Y, Keebler MV, Hooper R, Boulware MJ, Liu X, Churamani D, Abood ME, Walseth TF, Brailoiu E, Patel S, Marchant JS. The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation. Proceedings of the National Academy of Sciences of the United States of America. 111: 13087-92. PMID 25157141 DOI: 10.1073/Pnas.1407004111  0.8
2014 Brailoiu GC, Deliu E, Marcu J, Hoffman NE, Console-Bram L, Zhao P, Madesh M, Abood ME, Brailoiu E. Differential activation of intracellular versus plasmalemmal CB2 cannabinoid receptors. Biochemistry. 53: 4990-9. PMID 25033246 DOI: 10.1021/Bi500632A  0.8
2014 Console-Bram L, Brailoiu E, Brailoiu GC, Sharir H, Abood ME. Activation of GPR18 by cannabinoid compounds: a tale of biased agonism. British Journal of Pharmacology. 171: 3908-17. PMID 24762058 DOI: 10.1111/Bph.12746  0.8
2014 Shore DM, Baillie GL, Hurst DH, Navas F, Seltzman HH, Marcu JP, Abood ME, Ross RA, Reggio PH. Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling. The Journal of Biological Chemistry. 289: 5828-45. PMID 24366865 DOI: 10.1074/Jbc.M113.478495  0.8
2014 Zhao P, Lane TR, Gao HG, Hurst DP, Kotsikorou E, Le L, Brailoiu E, Reggio PH, Abood ME. Crucial positively charged residues for ligand activation of the GPR35 receptor. The Journal of Biological Chemistry. 289: 3625-38. PMID 24347166 DOI: 10.1074/Jbc.M113.508382  0.8
2014 Palma J, Abood ME, Barbe MF, Benamar K. Functional interaction between HIV-gp120 and opioid system in the preoptic anterior hypothalamus. Drug and Alcohol Dependence. 134: 383-6. PMID 24120859 DOI: 10.1016/J.Drugalcdep.2013.09.015  0.8
2013 Kotsikorou E, Sharir H, Shore DM, Hurst DP, Lynch DL, Madrigal KE, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak LS, Croatt MP, Abood ME, et al. Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 52: 9456-69. PMID 24274581 DOI: 10.1021/Bi4008885  0.8
2013 Yu J, Deliu E, Zhang XQ, Hoffman NE, Carter RL, Grisanti LA, Brailoiu GC, Madesh M, Cheung JY, Force T, Abood ME, Koch WJ, Tilley DG, Brailoiu E. Differential activation of cultured neonatal cardiomyocytes by plasmalemmal versus intracellular G protein-coupled receptor 55. The Journal of Biological Chemistry. 288: 22481-92. PMID 23814062 DOI: 10.1074/Jbc.M113.456178  0.8
2013 Marcu J, Shore DM, Kapur A, Trznadel M, Makriyannis A, Reggio PH, Abood ME. Novel insights into CB1 cannabinoid receptor signaling: a key interaction identified between the extracellular-3 loop and transmembrane helix 2. The Journal of Pharmacology and Experimental Therapeutics. 345: 189-97. PMID 23426954 DOI: 10.1124/Jpet.112.201046  0.8
2013 Baillie GL, Horswill JG, Anavi-Goffer S, Reggio PH, Bolognini D, Abood ME, McAllister S, Strange PG, Stephens GJ, Pertwee RG, Ross RA. CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity. Molecular Pharmacology. 83: 322-38. PMID 23160940 DOI: 10.1124/Mol.112.080879  0.8
2013 Zhao P, Abood ME. GPR55 and GPR35 and their relationship to cannabinoid and lysophospholipid receptors. Life Sciences. 92: 453-7. PMID 22820167 DOI: 10.1016/J.Lfs.2012.06.039  0.8
2013 Marcu J, Console-Bram L, Abood ME. Current cannabinoid receptor nomenclature and pharmacological principles Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders. 25-54. DOI: 10.1007/978-1-4614-7940-6_3  0.8
2012 Sharir H, Console-Bram L, Mundy C, Popoff SN, Kapur A, Abood ME. The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 856-65. PMID 22454039 DOI: 10.1007/S11481-012-9351-6  0.8
2012 Console-Bram L, Marcu J, Abood ME. Cannabinoid receptors: nomenclature and pharmacological principles. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38: 4-15. PMID 22421596 DOI: 10.1016/J.Pnpbp.2012.02.009  0.8
2011 Brailoiu GC, Oprea TI, Zhao P, Abood ME, Brailoiu E. Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide. The Journal of Biological Chemistry. 286: 29166-74. PMID 21719698 DOI: 10.1074/Jbc.M110.217463  0.8
2011 Kotsikorou E, Madrigal KE, Hurst DP, Sharir H, Lynch DL, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak L, Abood ME, Reggio PH. Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 50: 5633-47. PMID 21534610 DOI: 10.1021/bi200010k  0.8
2011 Persidsky Y, Ho W, Ramirez SH, Potula R, Abood ME, Unterwald E, Tuma R. HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions. Brain, Behavior, and Immunity. 25: S61-70. PMID 21397004 DOI: 10.1016/J.Bbi.2011.03.001  0.8
2011 Kotsikorou E, Lynch DL, Abood ME, Reggio PH. Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55. Chemistry and Physics of Lipids. 164: 131-43. PMID 21185816 DOI: 10.1016/J.Chemphyslip.2010.12.003  0.8
2010 Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, Greasley PJ, Hansen HS, Kunos G, Mackie K, Mechoulam R, Ross RA. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CBâ‚‚. Pharmacological Reviews. 62: 588-631. PMID 21079038 DOI: 10.1124/Pr.110.003004  0.8
2010 Zhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, ... Abood ME, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Molecular Pharmacology. 78: 560-8. PMID 20826425 DOI: 10.1124/Mol.110.066746  0.8
2010 Scotter EL, Abood ME, Glass M. The endocannabinoid system as a target for the treatment of neurodegenerative disease. British Journal of Pharmacology. 160: 480-98. PMID 20590559 DOI: 10.1111/J.1476-5381.2010.00735.X  0.8
2010 Carter GT, Abood ME, Aggarwal SK, Weiss MD. Cannabis and amyotrophic lateral sclerosis: hypothetical and practical applications, and a call for clinical trials. The American Journal of Hospice & Palliative Care. 27: 347-56. PMID 20439484 DOI: 10.1177/1049909110369531  0.8
2010 Sharir H, Abood ME. Pharmacological characterization of GPR55, a putative cannabinoid receptor. Pharmacology & Therapeutics. 126: 301-13. PMID 20298715 DOI: 10.1016/J.Pharmthera.2010.02.004  0.8
2010 Zhao P, Leonoudakis D, Abood ME, Beattie EC. Cannabinoid receptor activation reduces TNFalpha-induced surface localization of AMPAR-type glutamate receptors and excitotoxicity. Neuropharmacology. 58: 551-8. PMID 19654014 DOI: 10.1016/J.Neuropharm.2009.07.035  0.8
2010 Lane T, Abood ME, Reggio PH. GPR35: Study of Class a GPCR Sequence Divergences using Conformational Memories Biophysical Journal. 98: 6-6. DOI: 10.1016/J.Bpj.2009.12.3540  0.4
2009 Kapur A, Zhao P, Sharir H, Bai Y, Caron MG, Barak LS, Abood ME. Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands. The Journal of Biological Chemistry. 284: 29817-27. PMID 19723626 DOI: 10.1074/Jbc.M109.050187  0.8
2009 Zhang M, Adler MW, Abood ME, Ganea D, Jallo J, Tuma RF. CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury. Microvascular Research. 78: 86-94. PMID 19332079 DOI: 10.1016/J.Mvr.2009.03.005  0.8
2008 Nomura DK, Hudak CS, Ward AM, Burston JJ, Issa RS, Fisher KJ, Abood ME, Wiley JL, Lichtman AH, Casida JE. Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. Bioorganic & Medicinal Chemistry Letters. 18: 5875-8. PMID 18752948 DOI: 10.1016/J.Bmcl.2008.08.007  0.8
2008 Zhao P, Ignacio S, Beattie EC, Abood ME. Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity. The European Journal of Neuroscience. 27: 572-9. PMID 18279310 DOI: 10.1111/J.1460-9568.2008.06041.X  0.8
2008 Kapur A, Samaniego P, Thakur GA, Makriyannis A, Abood ME. Mapping the structural requirements in the CB1 cannabinoid receptor transmembrane helix II for signal transduction. The Journal of Pharmacology and Experimental Therapeutics. 325: 341-8. PMID 18174385 DOI: 10.1124/Jpet.107.133256  0.8
2007 Gehani NC, Nalwalk JW, Razdan RK, Martin BR, Sun X, Wentland M, Abood ME, Hough LB. Significance of cannabinoid CB1 receptors in improgan antinociception. The Journal of Pain : Official Journal of the American Pain Society. 8: 850-60. PMID 17644043 DOI: 10.1016/J.Jpain.2007.05.015  0.8
2007 Anavi-Goffer S, Fleischer D, Hurst DP, Lynch DL, Barnett-Norris J, Shi S, Lewis DL, Mukhopadhyay S, Howlett AC, Reggio PH, Abood ME. Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms. The Journal of Biological Chemistry. 282: 25100-13. PMID 17595161 DOI: 10.1074/Jbc.M703388200  0.8
2007 Kapur A, Hurst DP, Fleischer D, Whitnell R, Thakur GA, Makriyannis A, Reggio PH, Abood ME. Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7. Molecular Pharmacology. 71: 1512-24. PMID 17384224 DOI: 10.1124/Mol.107.034645  0.8
2006 Hurst D, Umejiego U, Lynch D, Seltzman H, Hyatt S, Roche M, McAllister S, Fleischer D, Kapur A, Abood M, Shi S, Jones J, Lewis D, Reggio P. Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction. Journal of Medicinal Chemistry. 49: 5969-87. PMID 17004712 DOI: 10.1021/Jm060446B  0.8
2006 Hough LB, de Esch IJ, Janssen E, Phillips J, Svokos K, Kern B, Trachler J, Abood ME, Leurs R, Nalwalk JW. Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic. Neuropharmacology. 51: 447-56. PMID 16806300 DOI: 10.1016/J.Neuropharm.2006.04.003  0.8
2006 Kim K, Moore DH, Makriyannis A, Abood ME. AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. European Journal of Pharmacology. 542: 100-5. PMID 16781706 DOI: 10.1016/J.Ejphar.2006.05.025  0.8
2005 Abood ME. Molecular biology of cannabinoid receptors Handbook of Experimental Pharmacology. 168: 81-115. PMID 16596772 DOI: 10.1007/3-540-26573-2_3  0.8
2005 Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A. (-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor. Molecular Pharmacology. 68: 1623-35. PMID 16157695 DOI: 10.1124/Mol.105.014407  0.8
2005 McAllister SD, Chan C, Taft RJ, Luu T, Abood ME, Moore DH, Aldape K, Yount G. Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells. Journal of Neuro-Oncology. 74: 31-40. PMID 16078104 DOI: 10.1007/S11060-004-5950-2  0.8
2004 McAllister SD, Hurst DP, Barnett-Norris J, Lynch D, Reggio PH, Abood ME. Structural mimicry in class A G protein-coupled receptor rotamer toggle switches: the importance of the F3.36(201)/W6.48(357) interaction in cannabinoid CB1 receptor activation. The Journal of Biological Chemistry. 279: 48024-37. PMID 15326174 DOI: 10.1074/Jbc.M406648200  0.8
2004 Raman C, McAllister SD, Rizvi G, Patel SG, Moore DH, Abood ME. Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 5: 33-9. PMID 15204022 DOI: 10.1080/14660820310016813  0.8
2003 McAllister SD, Rizvi G, Anavi-Goffer S, Hurst DP, Barnett-Norris J, Lynch DL, Reggio PH, Abood ME. An aromatic microdomain at the cannabinoid CB(1) receptor constitutes an agonist/inverse agonist binding region. Journal of Medicinal Chemistry. 46: 5139-52. PMID 14613317 DOI: 10.1021/Jm0302647  0.8
2002 McAllister SD, Tao Q, Barnett-Norris J, Buehner K, Hurst DP, Guarnieri F, Reggio PH, Nowell Harmon KW, Cabral GA, Abood ME. A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition. Biochemical Pharmacology. 63: 2121-36. PMID 12110371 DOI: 10.1016/S0006-2952(02)01031-6  0.8
2001 Abood ME, Rizvi G, Sallapudi N, McAllister SD. Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity Neuroscience Letters. 309: 197-201. PMID 11514075 DOI: 10.1016/S0304-3940(01)02065-1  0.8
2001 Kinard TA, Goforth PB, Tao Q, Abood ME, Teague J, Satin LS. Chloride channels regulate HIT cell volume but cannot fully account for swelling-induced insulin secretion. Diabetes. 50: 992-1003. PMID 11334443 DOI: 10.2337/Diabetes.50.5.992  0.8
2001 Griffin G, Williams S, Aung MM, Razdan RK, Martin BR, Abood ME. Separation of cannabinoid receptor affinity and efficacy in delta-8-tetrahydrocannabinol side-chain analogues. British Journal of Pharmacology. 132: 525-35. PMID 11159703 DOI: 10.1038/Sj.Bjp.0703827  0.8
2000 Mahadevan A, Siegel C, Martin BR, Abood ME, Beletskaya I, Razdan RK. Novel cannabinol probes for CB1 and CB2 cannabinoid receptors. Journal of Medicinal Chemistry. 43: 3778-85. PMID 11020293 DOI: 10.1021/Jm0001572  0.8
2000 Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding. Drug and Alcohol Dependence. 60: 133-40. PMID 10940540 DOI: 10.1016/S0376-8716(99)00152-0  0.8
2000 Griffin G, Tao Q, Abood ME. Cloning and pharmacological characterization of the rat CB2 cannabinoid receptor Journal of Pharmacology and Experimental Therapeutics. 292: 886-894. PMID 10688601  0.8
1999 Huffman JW, Liddle J, Yu S, Aung MM, Abood ME, Wiley JL, Martin BR. 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 7: 2905-14. PMID 10658595 DOI: 10.1016/S0968-0896(99)00219-9  0.8
1999 McAllister SD, Griffin G, Satin LS, Abood ME. Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. The Journal of Pharmacology and Experimental Therapeutics. 291: 618-26. PMID 10525080  0.8
1999 Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. 128: 684-8. PMID 10516649 DOI: 10.1038/Sj.Bjp.0702806  0.8
1999 Griffin G, Wray EJ, Tao Q, McAllister SD, Rorrer WK, Aung MM, Martin BR, Abood ME. Evaluation of the cannabinoid CB2 receptor-selective antagonist, SR144528: further evidence for cannabinoid CB2 receptor absence in the rat central nervous system. European Journal of Pharmacology. 377: 117-25. PMID 10448934 DOI: 10.1016/S0014-2999(99)00402-1  0.8
1999 Ng EW, Aung MM, Abood ME, Martin BR, Razdan RK. Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. Journal of Medicinal Chemistry. 42: 1975-81. PMID 10354405 DOI: 10.1021/Jm980711W  0.8
1999 Griffin G, Wray EJ, Rorrer WK, Crocker PJ, Ryan WJ, Saha B, Razdan RK, Martin BR, Abood ME. An investigation into the structural determinants of cannabinoid receptor ligand efficacy. British Journal of Pharmacology. 126: 1575-84. PMID 10323589 DOI: 10.1038/Sj.Bjp.0702469  0.8
1999 Tao Q, Mcallister SD, Andreassi J, Nowell KW, Cabral GA, Hurst DP, Bachtel K, Ekman MC, Reggio PH, Abood ME. Role of a conserved lysine residue in the peripheral cannabinoid receptor (CB2): Evidence for subtype specificity Molecular Pharmacology. 55: 605-613. PMID 10051546  0.8
1999 Aceto MD, Harris LS, Abood ME, Rice KC. Stereoselective mu- and delta-opioid receptor-related antinociception and binding with (+)-thebaine. European Journal of Pharmacology. 365: 143-7. PMID 9988096 DOI: 10.1016/S0014-2999(98)00862-0  0.8
1998 Reggio PH, Basu-Dutt S, Barnett-Norris J, Castro MT, Hurst DP, Seltzman HH, Roche MJ, Gilliam AF, Thomas BF, Stevenson LA, Pertwee RG, Abood ME. The bioactive conformation of aminoalkylindoles at the cannabinoid CB1 and CB2 receptors: insights gained from (E)- and (Z)-naphthylidene indenes. Journal of Medicinal Chemistry. 41: 5177-87. PMID 9857088 DOI: 10.1021/Jm9801197  0.8
1998 Nowell KW, Dove Pettit DA, Cabral WA, Zimmerman HW, Abood ME, Cabral GA. High-level expression of the human CB2 cannabinoid receptor using a baculovirus system Biochemical Pharmacology. 55: 1893-1905. PMID 9714308 DOI: 10.1016/S0006-2952(98)00081-1  0.8
1998 Tao Q, Abood ME. Mutation of a highly conserved aspartate residue in the second transmembrane domain of the cannabinoid receptors, CB1 and CB2, disrupts G- protein coupling Journal of Pharmacology and Experimental Therapeutics. 285: 651-658. PMID 9580609  0.8
1998 Griffin G, Atkinson PJ, Showalter VM, Martin BR, Abood ME. Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes. The Journal of Pharmacology and Experimental Therapeutics. 285: 553-60. PMID 9580597  0.8
1997 Reggio PH, Wang T, Brown AE, Fleming DN, Seltzman HH, Griffin G, Pertwee RG, Compton DR, Abood ME, Martin BR. Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity: synthesis and characterization of a series of O,2-propano-delta 8-tetrahydrocannabinol analogs. Journal of Medicinal Chemistry. 40: 3312-8. PMID 9379452 DOI: 10.1021/Jm970136G  0.8
1997 Abood ME, Ditto KE, Noel MA, Showalter VM, Tao Q. Isolation and expression of a mouse CB1 cannabinoid receptor gene. Comparison of binding properties with those of native CB1 receptors in mouse brain and N18TG2 neuroblastoma cells. Biochemical Pharmacology. 53: 207-14. PMID 9037253 DOI: 10.1016/S0006-2952(96)00727-7  0.8
1996 Abood ME, Martin BR. Molecular neurobiology of the cannabinoid receptor International Review of Neurobiology. 197-221. PMID 8894848 DOI: 10.1016/S0074-7742(08)60667-4  0.8
1996 Ishac EJ, Jiang L, Lake KD, Varga K, Abood ME, Kunos G. Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. British Journal of Pharmacology. 118: 2023-8. PMID 8864538 DOI: 10.1111/J.1476-5381.1996.Tb15639.X  0.8
1996 Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH. Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor. Journal of Medicinal Chemistry. 39: 3875-7. PMID 8831752 DOI: 10.1021/Jm960394Y  0.8
1996 Showalter VM, Compton DR, Martin BR, Abood ME. Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. The Journal of Pharmacology and Experimental Therapeutics. 278: 989-99. PMID 8819477  0.8
1996 Fan F, Tao Q, Abood M, Martin BR. Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55,940 on adenylyl cyclase in the cerebellum of CP 55,940-tolerant mice Brain Research. 706: 13-20. PMID 8720487 DOI: 10.1016/0006-8993(95)01113-7  0.36
1995 Pugh G, Abood ME, Welch SP. Antisense oligodeoxynucleotides to the κ-1 receptor block the antinociceptive effects of Δ9-THC in the spinal cord Brain Research. 689: 157-158. PMID 8528701 DOI: 10.1016/0006-8993(95)00560-D  0.8
1995 Abood ME, Noel MA, Carter RC, Harris LS. Evaluation of a series of N-alkyl benzomorphans in cell lines expressing transfected delta- and mu-opioid receptors. Biochemical Pharmacology. 50: 851-9. PMID 7575648 DOI: 10.1016/0006-2952(95)02007-Y  0.8
1995 Abood ME, Tao Q. Characterization of a delta opioid receptor in rat pheochromocytoma cells Journal of Pharmacology and Experimental Therapeutics. 274: 1566-1573. PMID 7562535  0.8
1995 McLaughlin CR, Tao Q, Abood ME. Analysis of the antinociceptive actions of the κ-opioid agonist enadoline (CI-977) in neonatal and adult rats: comparison to κ-opioid receptor mRNA ontogeny Drug and Alcohol Dependence. 38: 261-269. PMID 7555627 DOI: 10.1016/0376-8716(95)01124-H  0.8
1994 Martin BR, Welch SP, Abood M. Progress toward Understanding the Cannabinoid Receptor and Its Second Messenger Systems Advances in Pharmacology (San Diego). 25: 341-397. PMID 8204506 DOI: 10.1016/S1054-3589(08)60437-8  0.36
1994 McLaughlin CR, Martin BR, Compton DR, Abood ME. Cannabinoid receptors in developing rats: detection of mRNA and receptor binding. Drug and Alcohol Dependence. 36: 27-31. PMID 7988356 DOI: 10.1016/0376-8716(94)90006-X  0.8
1994 Pettit DAD, Showalter VM, Abood ME, Cabral GA. Expression of a cannabinoid receptor in baculo virus-infected insect cells Biochemical Pharmacology. 48: 1231-1243. PMID 7945417 DOI: 10.1016/0006-2952(94)90161-9  0.8
1994 Mclaughlin CR, Tao Q, Abood ME. Isolation and developmental expression of a rat cDNA encoding a cysteine-rich zinc finger protein Nucleic Acids Research. 22: 5477-5483. PMID 7816640 DOI: 10.1093/Nar/22.24.5477  0.8
1994 Abood ME, Noel MA, Farnsworth JS, Tao Q. Molecular cloning and expression of a delta-opioid receptor from rat brain. Journal of Neuroscience Research. 37: 714-9. PMID 7519274 DOI: 10.1002/Jnr.490370605  0.8
1993 McLaughlin CR, Abood ME. Developmental expression of cannabinoid receptor mRNA Developmental Brain Research. 76: 75-78. PMID 8306433 DOI: 10.1016/0165-3806(93)90124-S  0.8
1993 Abood ME, Sauss C, Fan F, Tilton CL, Martin BR. Development of behavioral tolerance to Δ9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain Pharmacology, Biochemistry and Behavior. 46: 575-579. PMID 8278434 DOI: 10.1016/0091-3057(93)90546-6  0.8
1993 Abood ME, Eubanks JS. Opioid receptors in pheochromocytoma cells: Receptor selectivity Nida Research Monograph Series. 111.  0.8
1992 Abood ME, Martin BR. Neurobiology of marijuana abuse Trends in Pharmacological Sciences. 13: 201-206. PMID 1604713 DOI: 10.1016/0165-6147(92)90064-D  0.8
1992 Kaminski NE, Abood ME, Kessler FK, Martin BR, Schatz AR. Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation Molecular Pharmacology. 42: 736-742. PMID 1279376  0.8
1990 Abood ME, Eberwine JH. Characterization and regulation of a cDNA clone for rat pancreastatin. Biochemical and Biophysical Research Communications. 167: 1079-85. PMID 2322259 DOI: 10.1016/0006-291X(90)90633-X  0.8
1990 Abood ME, Eberwine JH, Erdelyi E, Evans CJ. Regulation of both preproenkephalin mRNA and its derived opioids by haloperidol--a method for measurement of peptides and mRNA in the same tissue extract. Brain Research. Molecular Brain Research. 8: 243-8. PMID 2170802 DOI: 10.1016/0169-328X(90)90023-7  0.8
1987 Abood ME, Lee NM, Loh HH. Modification of opioid agonist binding by pertussis toxin. Brain Research. 417: 70-4. PMID 3113672 DOI: 10.1016/0006-8993(87)90180-6  0.8
1985 Abood ME, Law PY, Loh HH. Pertussis toxin treatment modifies opiate action in the rat brain striatum. Biochemical and Biophysical Research Communications. 127: 477-83. PMID 3919730 DOI: 10.1016/S0006-291X(85)80185-6  0.8
1985 Abood ME, Loh HH. Pertussis toxin treatment modifies opiate action in the rat brain striatum Federation Proceedings. 44.  0.8
1984 Bourne HR, Casperson GF, Van Dop C, Abood ME, Beiderman BB, Steinberg F, Walker N. Mutations of adenylate cyclase in yeast, mouse, and man. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 199-205. PMID 6328916  0.8
1982 Farfel Z, Abood ME, Brickman AS, Bourne HR. Deficient activity of receptor-cyclase coupling protein is transformed lymphoblasts of patients with pseudohypoparathyroidism, type I. The Journal of Clinical Endocrinology and Metabolism. 55: 113-7. PMID 6281299 DOI: 10.1210/Jcem-55-1-113  0.8
1982 Abood ME, Hurley JB, Pappone MC, Bourne HR, Stryer L. Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin. The Journal of Biological Chemistry. 257: 10540-3. PMID 6125514  0.8
1981 Kaslow HR, Groppi VE, Abood ME, Bourne HR. Cholera toxin can catalyze ADP-ribosylation of cytoskeletal proteins. The Journal of Cell Biology. 91: 410-3. PMID 7309789 DOI: 10.1083/Jcb.91.2.410  0.8
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