Wenbin Deng - Publications

Affiliations: 
Biochemistry and Molecular Biology University of California, Davis, Davis, CA 
Area:
Cell Biology, Molecular Biology, Biomedical Engineering

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Gao H, Guo Y, Biswas S, Li J, Zhang H, Chen Z, Deng W. Promoting Oligodendrocyte Differentiation from Human Induced Pluripotent Stem Cells by Activating Endocannabinoid Signaling for Treating Spinal Cord Injury. Stem Cell Reviews and Reports. PMID 35725998 DOI: 10.1007/s12015-022-10405-0  0.313
2021 Mayrhofer F, Dariychuk Z, Zhen A, Daugherty DJ, Bannerman P, Hanson AM, Pleasure D, Soulika A, Deng W, Chechneva OV. Reduction in CD11c microglia correlates with clinical progression in chronic experimental autoimmune demyelination. Neurobiology of Disease. 105556. PMID 34752925 DOI: 10.1016/j.nbd.2021.105556  0.665
2020 Cheng XY, Biswas S, Li J, Mao CJ, Chechneva O, Chen J, Li K, Li J, Zhang JR, Liu CF, Deng WB. Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria. Translational Neurodegeneration. 9: 13. PMID 32345341 DOI: 10.1186/S40035-020-00190-6  0.305
2020 Chen C, Jiang P, Xue H, Peterson SE, Tran HT, McCann AE, Parast MM, Li S, Pleasure DE, Laurent LC, Loring JF, Liu Y, Deng W. Author Correction: Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. Nature Communications. 11: 1070. PMID 32081845 DOI: 10.1038/S41467-020-14865-1  0.324
2019 Namchaiw P, Wen H, Mayrhofer F, Chechneva O, Biswas S, Deng W. Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro. Stem Cell Research & Therapy. 10: 272. PMID 31455382 DOI: 10.1186/S13287-019-1374-Y  0.407
2019 Biswas S, Chung SH, Jiang P, Dehghan S, Deng W. Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo. Scientific Reports. 9: 9013. PMID 31227736 DOI: 10.1038/S41598-019-45247-3  0.448
2019 Wen H, Xiao W, Biswas S, Cong Z, Liu XM, Lam KS, Liao YH, Deng W. An Alginate Hydrogel Modified with a Ligand Interacting with α3β1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids towards Oligodendrocytes in vitro. Acs Applied Materials & Interfaces. PMID 30645095 DOI: 10.1021/Acsami.8B19438  0.327
2018 Thai PN, Daugherty DJ, Frederich BJ, Lu X, Deng W, Bers DM, Dedkova EN, Schaefer S. Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Pressure Overload Induced Heart Failure. Scientific Reports. 8: 16213. PMID 30385779 DOI: 10.1038/S41598-018-34451-2  0.655
2018 Mokhtarzadeh Khanghahi A, Satarian L, Deng W, Baharvand H, Javan M. In vivo conversion of astrocytes into oligodendrocyte lineage cells with transcription factor Sox10; Promise for myelin repair in multiple sclerosis. Plos One. 13: e0203785. PMID 30212518 DOI: 10.1371/Journal.Pone.0203785  0.434
2018 Mizuno GO, Wang Y, Shi G, Wang Y, Sun J, Papadopoulos S, Broussard GJ, Unger EK, Deng W, Weick J, Bhattacharyya A, Chen CY, Yu G, Looger LL, Tian L. Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model. Cell Reports. 24: 355-365. PMID 29996097 DOI: 10.1016/J.Celrep.2018.06.033  0.313
2018 Chung SH, Biswas S, Sohn J, Jiang P, Dehghan S, Marzban H, Deng W. The p38α MAPK deletion in oligodendroglia does not attenuate myelination defects in a mouse model of periventricular leukomalacia. Neuroscience. PMID 29966722 DOI: 10.1016/J.Neuroscience.2018.06.037  0.383
2017 Cheng XY, Li SY, Mao CJ, Wang MX, Chen J, Wang F, Wang GH, Deng WB, Li XK, Liu CF. Serum Response Factor Promotes Dopaminergic Neuron Survival via Activation of Beclin 1-Dependent Autophagy. Neuroscience. 371: 288-295. PMID 29196028 DOI: 10.1016/J.Neuroscience.2017.11.040  0.317
2017 Tian Z, Zhao Q, Biswas S, Deng W. Methods of reactivation and reprogramming of neural stem cells for neural repair. Methods (San Diego, Calif.). PMID 28864354 DOI: 10.1016/J.Ymeth.2017.08.014  0.41
2017 Xiao J, Yang R, Biswas S, Zhu Y, Qin X, Zhang M, Zhai L, Luo Y, He X, Mao C, Deng W. Neural Stem Cell-Based Regenerative Approaches for the Treatment of Multiple Sclerosis. Molecular Neurobiology. PMID 28466274 DOI: 10.1007/S12035-017-0566-7  0.405
2017 Thai PN, Daugherty D, Frederich BJ, Galice S, Deng W, Bers DM, Schaefer S, Dedkova EN. Emerging Role of the Mitochondrial Outer Membrane Translocator Protein (TSPO) in Heart Failure and Mitochondrai Quality Control Biophysical Journal. 112: 325a. DOI: 10.1016/J.Bpj.2016.11.1758  0.655
2016 Jiang P, Deng W. Regenerating white matter using human iPSC-derived immature astroglia. Neurogenesis (Austin, Tex.). 3: e1224453. PMID 27652287 DOI: 10.1080/23262133.2016.1224453  0.312
2016 Chechneva OV, Deng W. Mitochondrial translocator protein (TSPO), astrocytes and neuroinflammation. Neural Regeneration Research. 11: 1056-1057. PMID 27630677 DOI: 10.4103/1673-5374.187027  0.323
2016 Yechikov S, Copaciu R, Gluck JM, Deng W, Chiamvimonvat N, Chan JW, Lieu DK. Same-Single-Cell Analysis of Pacemaker-Specific Markers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Subtypes Classified by Electrophysiology. Stem Cells (Dayton, Ohio). PMID 27434649 DOI: 10.1002/Stem.2466  0.379
2016 Jiang P, Chen C, Liu XB, Pleasure DE, Liu Y, Deng W. Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion. Cell Reports. PMID 27134175 DOI: 10.1016/J.Celrep.2016.04.011  0.426
2016 Tian Z, Guo F, Biswas S, Deng W. Rationale and Methodology of Reprogramming for Generation of Induced Pluripotent Stem Cells and Induced Neural Progenitor Cells. International Journal of Molecular Sciences. 17. PMID 27104529 DOI: 10.3390/Ijms17040594  0.408
2016 Daugherty DJ, Chechneva O, Mayrhofer F, Deng W. The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis. Scientific Reports. 6: 22556. PMID 26925573 DOI: 10.1038/Srep22556  0.704
2016 Zhai L, Wang L, Teng F, Zhou L, Zhang W, Xiao J, Liu Y, Deng W. Argonaute and Argonaute-Bound Small RNAs in Stem Cells. International Journal of Molecular Sciences. 17. PMID 26861290 DOI: 10.3390/Ijms17020208  0.318
2015 Chen C, Chan A, Wen H, Chung SH, Deng W, Jiang P. Stem and Progenitor Cell-Derived Astroglia Therapies for Neurological Diseases. Trends in Molecular Medicine. PMID 26443123 DOI: 10.1016/J.Molmed.2015.09.003  0.413
2015 Liu Y, Deng W. Reverse engineering human neurodegenerative disease using pluripotent stem cell technology. Brain Research. PMID 26423934 DOI: 10.1016/J.Brainres.2015.09.023  0.393
2015 Li S, Xue H, Wu J, Rao MS, Kim DH, Deng W, Liu Y. Human induced pluripotent stem cell NEUROG2 dual knockin reporter lines generated by the CRISPR/Cas9 system. Stem Cells and Development. PMID 26414932 DOI: 10.1089/Scd.2015.0131  0.374
2015 Xiao J, Liu W, Chen Y, Deng W. Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis. Journal of Neuroinflammation. 12: 117. PMID 26068104 DOI: 10.1186/S12974-015-0338-0  0.38
2015 Chung SH, Biswas S, Selvaraj V, Liu XB, Sohn J, Jiang P, Chen C, Chmilewsky F, Marzban H, Horiuchi M, Pleasure DE, Deng W. The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS. Cell Death & Disease. 6: e1748. PMID 25950478 DOI: 10.1038/Cddis.2015.119  0.412
2015 Xiao J, Yang R, Biswas S, Qin X, Zhang M, Deng W. Mesenchymal stem cells and induced pluripotent stem cells as therapies for multiple sclerosis. International Journal of Molecular Sciences. 16: 9283-302. PMID 25918935 DOI: 10.3390/Ijms16059283  0.422
2015 Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F. The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5007-22. PMID 25810530 DOI: 10.1523/Jneurosci.4787-14.2015  0.324
2015 Xiao J, Yang R, Yang L, Fan X, Liu W, Deng W. Kirenol attenuates experimental autoimmune encephalomyelitis by inhibiting differentiation of Th1 and th17 cells and inducing apoptosis of effector T cells. Scientific Reports. 5: 9022. PMID 25762107 DOI: 10.1038/Srep09022  0.357
2015 Sohn J, Orosco L, Guo F, Chung SH, Bannerman P, Mills Ko E, Zarbalis K, Deng W, Pleasure D. The subventricular zone continues to generate corpus callosum and rostral migratory stream astroglia in normal adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3756-63. PMID 25740506 DOI: 10.1523/Jneurosci.3454-14.2015  0.367
2014 Lo U, Selvaraj V, Plane JM, Chechneva OV, Otsu K, Deng W. p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes. Scientific Reports. 4: 7405. PMID 25502009 DOI: 10.1038/Srep07405  0.356
2014 Chechneva OV, Mayrhofer F, Daugherty DJ, Krishnamurty RG, Bannerman P, Pleasure DE, Deng W. A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury. Cell Death & Disease. 5: e1481. PMID 25341035 DOI: 10.1038/Cddis.2014.446  0.647
2014 Chen C, Jiang P, Xue H, Peterson SE, Tran HT, McCann AE, Parast MM, Li S, Pleasure DE, Laurent LC, Loring JF, Liu Y, Deng W. Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. Nature Communications. 5: 4430. PMID 25034944 DOI: 10.1038/Ncomms5430  0.341
2014 Morohaku K, Pelton SH, Daugherty DJ, Butler WR, Deng W, Selvaraj V. Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis. Endocrinology. 155: 89-97. PMID 24174323 DOI: 10.1210/En.2013-1556  0.665
2013 Jiang P, Chen C, Liu XB, Selvaraj V, Liu W, Feldman DH, Liu Y, Pleasure DE, Li RA, Deng W. Generation and characterization of spiking and nonspiking oligodendroglial progenitor cells from embryonic stem cells. Stem Cells (Dayton, Ohio). 31: 2620-31. PMID 23940003 DOI: 10.1002/Stem.1515  0.428
2013 Jiang P, Chen C, Wang R, Chechneva OV, Chung SH, Rao MS, Pleasure DE, Liu Y, Zhang Q, Deng W. hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. Nature Communications. 4: 2196. PMID 23880652 DOI: 10.1038/Ncomms3196  0.418
2013 Daugherty DJ, Selvaraj V, Chechneva OV, Liu XB, Pleasure DE, Deng W. A TSPO ligand is protective in a mouse model of multiple sclerosis. Embo Molecular Medicine. 5: 891-903. PMID 23681668 DOI: 10.1002/Emmm.201202124  0.683
2013 Chung SH, Guo F, Jiang P, Pleasure DE, Deng W. Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. Cell Death & Disease. 4: e546. PMID 23492777 DOI: 10.1038/Cddis.2013.74  0.453
2013 Liu XB, Shen Y, Plane JM, Deng W. Vulnerability of premyelinating oligodendrocytes to white-matter damage in neonatal brain injury. Neuroscience Bulletin. 29: 229-38. PMID 23456565 DOI: 10.1007/S12264-013-1311-5  0.321
2013 Liu W, Deng Y, Liu Y, Gong W, Deng W. Stem cell models for drug discovery and toxicology studies. Journal of Biochemical and Molecular Toxicology. 27: 17-27. PMID 23293059 DOI: 10.1002/Jbt.21470  0.379
2012 Sohn J, Selvaraj V, Wakayama K, Orosco L, Lee E, Crawford SE, Guo F, Lang J, Horiuchi M, Zarbalis K, Itoh T, Deng W, Pleasure D. PEDF is a novel oligodendrogenic morphogen acting on the adult SVZ and corpus callosum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12152-64. PMID 22933798 DOI: 10.1523/Jneurosci.0628-12.2012  0.403
2012 Chen C, Daugherty D, Jiang P, Deng W. Oligodendrocyte progenitor cells derived from mouse embryonic stem cells give rise to type-1 and type-2 astrocytes in vitro. Neuroscience Letters. 523: 180-5. PMID 22781495 DOI: 10.1016/J.Neulet.2012.06.072  0.683
2012 Plane JM, Grossenbacher SK, Deng W. PARP-1 deletion promotes subventricular zone neural stem cells toward a glial fate. Journal of Neuroscience Research. 90: 1489-506. PMID 22431411 DOI: 10.1002/Jnr.23040  0.455
2012 Selvaraj V, Jiang P, Chechneva O, Lo UG, Deng W. Differentiating human stem cells into neurons and glial cells for neural repair. Frontiers in Bioscience (Landmark Edition). 17: 65-89. PMID 22201733 DOI: 10.2741/3916  0.73
2012 Shen Y, Liu XB, Pleasure DE, Deng W. Axon-glia synapses are highly vulnerable to white matter injury in the developing brain. Journal of Neuroscience Research. 90: 105-21. PMID 21812016 DOI: 10.1002/Jnr.22722  0.328
2011 Soundarapandian MM, Selvaraj V, Lo UG, Golub MS, Feldman DH, Pleasure DE, Deng W. Zfp488 promotes oligodendrocyte differentiation of neural progenitor cells in adult mice after demyelination. Scientific Reports. 1: 2. PMID 22355521 DOI: 10.1038/Srep00002  0.739
2011 Lo KY, Sun YS, Landry JP, Zhu X, Deng W. Label-free detection of surface markers on stem cells by oblique-incidence reflectivity difference microscopy. Biotechniques. 50: 381-8. PMID 21781038 DOI: 10.2144/000113670  0.332
2011 Chechneva OV, Mayrhofer F, Daugherty DJ, Pleasure DE, Hong JS, Deng W. Low dose dextromethorphan attenuates moderate experimental autoimmune encephalomyelitis by inhibiting NOX2 and reducing peripheral immune cells infiltration in the spinal cord. Neurobiology of Disease. 44: 63-72. PMID 21704706 DOI: 10.1016/J.Nbd.2011.06.004  0.657
2011 Liu W, Shen Y, Plane JM, Pleasure DE, Deng W. Neuroprotective potential of erythropoietin and its derivative carbamylated erythropoietin in periventricular leukomalacia. Experimental Neurology. 230: 227-39. PMID 21596035 DOI: 10.1016/J.Expneurol.2011.04.021  0.398
2011 Wang YZ, Plane JM, Jiang P, Zhou CJ, Deng W. Concise review: Quiescent and active states of endogenous adult neural stem cells: identification and characterization. Stem Cells (Dayton, Ohio). 29: 907-12. PMID 21557389 DOI: 10.1002/Stem.644  0.365
2011 Liu Y, Jiang P, Deng W. OLIG gene targeting in human pluripotent stem cells for motor neuron and oligodendrocyte differentiation. Nature Protocols. 6: 640-55. PMID 21527921 DOI: 10.1038/Nprot.2011.310  0.396
2011 Zhang J, Calafiore M, Zeng Q, Zhang X, Huang Y, Li RA, Deng W, Zhao M. Electrically guiding migration of human induced pluripotent stem cells. Stem Cell Reviews. 7: 987-96. PMID 21373881 DOI: 10.1042/Cbi034S042D  0.375
2011 Chung SH, Calafiore M, Plane JM, Pleasure DE, Deng W. Apoptosis inducing factor deficiency causes reduced mitofusion 1 expression and patterned Purkinje cell degeneration. Neurobiology of Disease. 41: 445-57. PMID 20974255 DOI: 10.1016/J.Nbd.2010.10.016  0.389
2010 Jantzie LL, Talos DM, Selip DB, An L, Jackson MC, Folkerth RD, Deng W, Jensen FE. Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia. Neuron Glia Biology. 6: 277-88. PMID 22169210 DOI: 10.1017/S1740925X11000111  0.346
2010 Plane JM, Shen Y, Pleasure DE, Deng W. Prospects for minocycline neuroprotection. Archives of Neurology. 67: 1442-8. PMID 20697034 DOI: 10.1001/Archneurol.2010.191  0.301
2010 Jiang P, Selvaraj V, Deng W. Differentiation of embryonic stem cells into oligodendrocyte precursors. Journal of Visualized Experiments : Jove. PMID 20489683 DOI: 10.3791/1960  0.428
2010 Shen Y, Plane JM, Deng W. Mouse models of periventricular leukomalacia. Journal of Visualized Experiments : Jove. PMID 20485263 DOI: 10.3791/1951  0.372
2010 Liu DZ, Ander BP, Xu H, Shen Y, Kaur P, Deng W, Sharp FR. Blood-brain barrier breakdown and repair by Src after thrombin-induced injury. Annals of Neurology. 67: 526-33. PMID 20437588 DOI: 10.1002/Ana.21924  0.309
2010 Deng W. AID in reprogramming: quick and efficient: identification of a key enzyme called AID, and its activity in DNA demethylation, may help to overcome a pivotal epigenetic barrier in reprogramming somatic cells toward pluripotency. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 385-7. PMID 20394066 DOI: 10.1002/Bies.201000014  0.375
2010 Deng W. Induced pluripotent stem cells: paths to new medicines. A catalyst for disease modelling, drug discovery and regenerative therapy. Embo Reports. 11: 161-5. PMID 20168328 DOI: 10.1038/Embor.2010.15  0.384
2010 Selvaraj V, Plane JM, Williams AJ, Deng W. Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies. Trends in Biotechnology. 28: 214-23. PMID 20149468 DOI: 10.1016/J.Tibtech.2010.01.002  0.632
2010 Jiang P, Rushing SN, Kong CW, Fu J, Lieu DK, Chan CW, Deng W, Li RA. Electrophysiological properties of human induced pluripotent stem cells. American Journal of Physiology. Cell Physiology. 298: C486-95. PMID 19955484 DOI: 10.1152/Ajpcell.00251.2009  0.332
2009 Deng W, Xu Y. Genome integrity: linking pluripotency and tumorgenicity. Trends in Genetics : Tig. 25: 425-7. PMID 19801173 DOI: 10.1016/J.Tig.2009.09.004  0.345
2009 Selvaraj V, Soundarapandian MM, Chechneva O, Williams AJ, Sidorov MK, Soulika AM, Pleasure DE, Deng W. PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis. The Journal of Biological Chemistry. 284: 26070-84. PMID 19628872 DOI: 10.1074/Jbc.M109.013474  0.628
2006 Deng W, Yue Q, Rosenberg PA, Volpe JJ, Jensen FE. Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function. Journal of Neurochemistry. 98: 213-22. PMID 16606353 DOI: 10.1111/J.1471-4159.2006.03861.X  0.314
2004 Deng W, Wang H, Rosenberg PA, Volpe JJ, Jensen FE. Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 101: 7751-6. PMID 15136737 DOI: 10.1073/Pnas.0307850101  0.301
2004 Follett PL, Deng W, Dai W, Talos DM, Massillon LJ, Rosenberg PA, Volpe JJ, Jensen FE. Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4412-20. PMID 15128855 DOI: 10.1523/Jneurosci.0477-04.2004  0.332
2003 Deng W, Rosenberg PA, Volpe JJ, Jensen FE. Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors. Proceedings of the National Academy of Sciences of the United States of America. 100: 6801-6. PMID 12743362 DOI: 10.1073/Pnas.1136624100  0.322
2003 Deng W, Poretz RD. Oligodendroglia in developmental neurotoxicity. Neurotoxicology. 24: 161-78. PMID 12606289 DOI: 10.1016/S0161-813X(02)00196-1  0.423
2002 Deng W, Poretz RD. Protein kinase C activation is required for the lead-induced inhibition of proliferation and differentiation of cultured oligodendroglial progenitor cells. Brain Research. 929: 87-95. PMID 11852034 DOI: 10.1016/S0006-8993(01)03385-6  0.359
2001 Deng W, Poretz RD. Lead alters the developmental profile of the galactolipid metabolic enzymes in cultured oligodendrocyte lineage cells. Neurotoxicology. 22: 429-37. PMID 11577801 DOI: 10.1016/S0161-813X(01)00048-1  0.383
2001 Deng W, McKinnon RD, Poretz RD. Lead exposure delays the differentiation of oligodendroglial progenitors in vitro. Toxicology and Applied Pharmacology. 174: 235-44. PMID 11485384 DOI: 10.1006/Taap.2001.9219  0.377
2001 Deng W, Poretz RD. Lead exposure affects levels of galactolipid metabolic enzymes in the developing rat brain Toxicology and Applied Pharmacology. 172: 98-107. PMID 11298496 DOI: 10.1006/Taap.2001.9142  0.326
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