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Yuh-Hwa Wang - Publications

Affiliations: 
Biochemistry and Molecular Biology Wake Forest University, Winston-Salem, NC, United States 
Area:
Biochemistry
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Michel N, Young HMR, Atkin ND, Arshad U, Al-Humadi R, Singh S, Manukyan A, Gore L, Burbulis IE, Wang YH, McConnell MJ. Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis. Scientific Reports. 12: 12156. PMID 35840793 DOI: 10.1038/s41598-022-16516-5  0.303
2021 Atkin ND, Raimer HM, Wang Z, Zang C, Wang YH. Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites. Genes, Chromosomes & Cancer. PMID 34405474 DOI: 10.1002/gcc.22993  0.389
2020 Szlachta K, Manukyan A, Raimer HM, Singh S, Salamon A, Guo W, Lobachev KS, Wang YH. Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks. Nucleic Acids Research. PMID 32501506 DOI: 10.1093/Nar/Gkaa483  0.479
2020 Singh S, Szlachta K, Manukyan A, Raimer HM, Dinda M, Bekiranov S, Wang YH. Pausing sites of RNA polymerase II on actively transcribed genes are enriched with DNA double-stranded breaks. The Journal of Biological Chemistry. PMID 32029477 DOI: 10.1074/Jbc.Ra119.011665  0.403
2020 Szlachta K, Raimer HM, Comeau LD, Wang YH. CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution. Bmc Genomics. 21: 25. PMID 31914926 DOI: 10.1186/S12864-019-6436-0  0.417
2019 Atkin ND, Raimer HM, Wang YH. Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility. Genes. 10. PMID 31614754 DOI: 10.3390/Genes10100791  0.425
2019 Irony-Tur Sinai M, Salamon A, Stanleigh N, Goldberg T, Weiss A, Wang YH, Kerem B. AT-dinucleotide rich sequences drive fragile site formation. Nucleic Acids Research. PMID 31410468 DOI: 10.1093/Nar/Gkz689  0.493
2018 Huckaby AC, Granum CS, Carey MA, Szlachta K, Al-Barghouthi B, Wang YH, Guler JL. Complex DNA structures trigger copy number variation across the Plasmodium falciparum genome. Nucleic Acids Research. PMID 30576466 DOI: 10.1093/Nar/Gky1268  0.381
2018 Szlachta K, Thys RG, Atkin ND, Pierce LCT, Bekiranov S, Wang YH. Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human. Genome Biology. 19: 89. PMID 30001206 DOI: 10.1186/S13059-018-1463-8  0.402
2017 Lehman CE, Dillon LW, Nikiforov YE, Wang YH. DNA Fragile Site Breakage as a Measure of Chemical Exposure and Predictor of Individual Susceptibility to Form Oncogenic Rearrangements. Carcinogenesis. PMID 28069693 DOI: 10.1093/Carcin/Bgw210  0.476
2015 Thys RG, Wang YH. DNA replication dynamics of the GGGGCC repeat of C9orf72. The Journal of Biological Chemistry. PMID 26463209 DOI: 10.1074/Jbc.M115.660324  0.426
2015 Thys RG, Lehman CE, Pierce LC, Wang YH. Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells. Mutation Research. 779: 86-95. PMID 26163765 DOI: 10.1016/J.Mrfmmm.2015.06.011  0.469
2015 Dillon LW, Kumar P, Shibata Y, Wang YH, Willcox S, Griffith JD, Pommier Y, Takeda S, Dutta A. Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity. Cell Reports. 11: 1749-59. PMID 26051933 DOI: 10.1016/J.Celrep.2015.05.020  0.336
2015 Thys RG, Lehman CE, Pierce LC, Wang YH. DNA secondary structure at chromosomal fragile sites in human disease. Current Genomics. 16: 60-70. PMID 25937814 DOI: 10.2174/1389202916666150114223205  0.502
2014 Reddy K, Schmidt MH, Geist JM, Thakkar NP, Panigrahi GB, Wang YH, Pearson CE. Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability. Nucleic Acids Research. 42: 10473-87. PMID 25147206 DOI: 10.1093/Nar/Gku658  0.304
2013 Axford MM, Wang YH, Nakamori M, Zannis-Hadjopoulos M, Thornton CA, Pearson CE. Detection of slipped-DNAs at the trinucleotide repeats of the myotonic dystrophy type I disease locus in patient tissues. Plos Genetics. 9: e1003866. PMID 24367268 DOI: 10.1371/Journal.Pgen.1003866  0.376
2013 Dillon LW, Pierce LC, Lehman CE, Nikiforov YE, Wang YH. DNA topoisomerases participate in fragility of the oncogene RET. Plos One. 8: e75741. PMID 24040417 DOI: 10.1371/Journal.Pone.0075741  0.461
2013 Dillon LW, Pierce LC, Ng MC, Wang YH. Role of DNA secondary structures in fragile site breakage along human chromosome 10. Human Molecular Genetics. 22: 1443-56. PMID 23297364 DOI: 10.1093/Hmg/Dds561  0.502
2012 Dillon LW, Lehman CE, Wang YH. The role of fragile sites in sporadic papillary thyroid carcinoma. Journal of Thyroid Research. 2012: 927683. PMID 22762011 DOI: 10.1155/2012/927683  0.397
2011 Weckerle AB, Santra M, Ng MC, Koty PP, Wang YH. CBFB and MYH11 in inv(16)(p13q22) of acute myeloid leukemia displaying close spatial proximity in interphase nuclei of human hematopoietic stem cells. Genes, Chromosomes & Cancer. 50: 746-55. PMID 21638519 DOI: 10.1002/Gcc.20896  0.534
2010 Dillon LW, Burrow AA, Wang YH. DNA instability at chromosomal fragile sites in cancer. Current Genomics. 11: 326-37. PMID 21286310 DOI: 10.2174/138920210791616699  0.527
2010 Gandhi M, Dillon LW, Pramanik S, Nikiforov YE, Wang YH. DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells Oncogene. 29: 2272-2280. PMID 20101222 DOI: 10.1038/Onc.2009.502  0.504
2010 Burrow AA, Marullo A, Holder LR, Wang YH. Secondary structure formation and DNA instability at fragile site FRA16B. Nucleic Acids Research. 38: 2865-77. PMID 20071743 DOI: 10.1093/Nar/Gkp1245  0.483
2010 Wan C, Kulkarni A, Wang YH. ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment. Mutation Research. 686: 39-46. PMID 20060399 DOI: 10.1016/J.Mrfmmm.2009.12.012  0.381
2009 Burrow AA, Williams LE, Pierce LC, Wang YH. Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites. Bmc Genomics. 10: 59. PMID 19183484 DOI: 10.1186/1471-2164-10-59  0.511
2009 Hagerman KA, Ruan H, Edamura KN, Matsuura T, Pearson CE, Wang YH. The ATTCT repeats of spinocerebellar ataxia type 10 display strong nucleosome assembly which is enhanced by repeat interruptions. Gene. 434: 29-34. PMID 19171184 DOI: 10.1016/J.Gene.2008.12.011  0.385
2006 Wang YH. Chromatin structure of human chromosomal fragile sites. Cancer Letters. 232: 70-8. PMID 16229940 DOI: 10.1016/j.canlet.2005.07.040  0.336
2004 Mulvihill DJ, Wang YH. Two breakpoint clusters at fragile site FRA3B form phased nucleosomes. Genome Research. 14: 1350-7. PMID 15231750 DOI: 10.1101/Gr.2304404  0.397
2002 Pearson CE, Tam M, Wang YH, Montgomery SE, Dar AC, Cleary JD, Nichol K. Slipped-strand DNAs formed by long (CAG)*(CTG) repeats: slipped-out repeats and slip-out junctions. Nucleic Acids Research. 30: 4534-47. PMID 12384601 DOI: 10.1093/Nar/Gkf572  0.378
2002 Hsu YY, Wang YH. Human fragile site FRA16B DNA excludes nucleosomes in the presence of distamycin. The Journal of Biological Chemistry. 277: 17315-9. PMID 11880377 DOI: 10.1074/jbc.M200901200  0.301
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