Timothy A. McCaffrey - Publications

Affiliations: 
Biochemistry and Molecular Biology The George Washington University, Washington, DC, United States 
Area:
Molecular Biology, Biochemistry, Medicine and Surgery

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 St Laurent G, Seilheimer B, Tackett M, Zhou J, Shtokalo D, Vyatkin Y, Ri M, Toma I, Jones D, McCaffrey TA. Deep Sequencing Transcriptome Analysis of Murine Wound Healing: Effects of a Multicomponent, Multitarget Natural Product Therapy-Tr14. Frontiers in Molecular Biosciences. 4: 57. PMID 28879183 DOI: 10.3389/fmolb.2017.00057  1
2016 Chawla LS, Toma I, Davison D, Vaziri K, Lee J, Lucas R, Seneff MG, Nyhan A, McCaffrey TA. Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes. Bmc Medical Genomics. 9: 40. PMID 27417541 DOI: 10.1186/s12920-016-0200-y  1
2016 Hilton SK, Castro-Nallar E, Pérez-Losada M, Toma I, McCaffrey TA, Hoffman EP, Siegel MO, Simon GL, Johnson WE, Crandall KA. Metataxonomic and Metagenomic Approaches vs. Culture-Based Techniques for Clinical Pathology. Frontiers in Microbiology. 7: 484. PMID 27092134 DOI: 10.3389/fmicb.2016.00484  1
2016 Laurent GS, Vyatkin Y, Antonets D, Ri M, Qi Y, Saik O, Shtokalo D, de Hoon MJ, Kawaji H, Itoh M, Lassmann T, Arner E, Forrest AR, Nicolas E, ... McCaffrey TA, et al. Functional annotation of the vlinc class of non-coding RNAs using systems biology approach. Nucleic Acids Research. PMID 27001520 DOI: 10.1093/nar/gkw162  1
2015 Liu T, Zhang J, Chen X, Feng X, Fu SW, McCaffrey TA, Liu M. Comparison between urinary 11-dehydrothromboxane B2 detection and platelet Light Transmission Aggregometry (LTA) assays for evaluating aspirin response in elderly patients with coronary artery disease. Gene. PMID 26095809 DOI: 10.1016/j.gene.2015.06.045  1
2014 Toma I, Siegel MO, Keiser J, Yakovleva A, Kim A, Davenport L, Devaney J, Hoffman EP, Alsubail R, Crandall KA, Castro-Nallar E, Pérez-Losada M, Hilton SK, Chawla LS, McCaffrey TA, et al. Single-molecule long-read 16S sequencing to characterize the lung microbiome from mechanically ventilated patients with suspected pneumonia. Journal of Clinical Microbiology. 52: 3913-21. PMID 25143582 DOI: 10.1128/JCM.01678-14  1
2014 Lai Y, Zhang F, Nayak TK, Modarres R, Lee NH, McCaffrey TA. Concordant integrative gene set enrichment analysis of multiple large-scale two-sample expression data sets. Bmc Genomics. 15: S6. PMID 24564564 DOI: 10.1186/1471-2164-15-S1-S6  1
2013 St Laurent G, Shtokalo D, Dong B, Tackett MR, Fan X, Lazorthes S, Nicolas E, Sang N, Triche TJ, McCaffrey TA, Xiao W, Kapranov P. VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer. Genome Biology. 14: R73. PMID 23876380 DOI: 10.1186/gb-2013-14-7-r73  1
2013 Voora D, Cyr D, Lucas J, Chi JT, Dungan J, McCaffrey TA, Katz R, Newby LK, Kraus WE, Becker RC, Ortel TL, Ginsburg GS. Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. Journal of the American College of Cardiology. 62: 1267-76. PMID 23831034 DOI: 10.1016/j.jacc.2013.05.073  1
2013 McCaffrey TA, Tziros C, Lewis J, Katz R, Siegel R, Weglicki W, Kramer J, Mak IT, Toma I, Chen L, Benas E, Lowitt A, Rao S, Witkin L, Lian Y, et al. Genomic profiling reveals the potential role of TCL1A and MDR1 deficiency in chemotherapy-induced cardiotoxicity. International Journal of Biological Sciences. 9: 350-60. PMID 23630447 DOI: 10.7150/ijbs.6058  1
2013 St Laurent G, Shtokalo D, Tackett MR, Yang Z, Vyatkin Y, Milos PM, Seilheimer B, McCaffrey TA, Kapranov P. On the importance of small changes in RNA expression. Methods (San Diego, Calif.). 63: 18-24. PMID 23563143 DOI: 10.1016/j.ymeth.2013.03.027  1
2013 Fallahi P, Katz R, Toma I, Li R, Reiner J, VanHouten K, Carpio L, Marshall L, Lian Y, Bupp S, Fu SW, Rickles F, Leitenberg D, Lai Y, Weksler BB, ... ... McCaffrey TA, et al. Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction. Gene. 520: 131-8. PMID 23454623 DOI: 10.1016/j.gene.2013.02.032  1
2013 Chen L, Li Y, Fu Y, Peng J, Mo MH, Stamatakos M, Teal CB, Brem RF, Stojadinovic A, Grinkemeyer M, McCaffrey TA, Man YG, Fu SW. Role of deregulated microRNAs in breast cancer progression using FFPE tissue. Plos One. 8: e54213. PMID 23372687 DOI: 10.1371/journal.pone.0054213  1
2012 St Laurent G, Shtokalo D, Tackett MR, Yang Z, Eremina T, Wahlestedt C, Urcuqui-Inchima S, Seilheimer B, McCaffrey TA, Kapranov P. Intronic RNAs constitute the major fraction of the non-coding RNA in mammalian cells. Bmc Genomics. 13: 504. PMID 23006825 DOI: 10.1186/1471-2164-13-504  1
2012 Toma I, McCaffrey TA. Transforming growth factor-β and atherosclerosis: interwoven atherogenic and atheroprotective aspects. Cell and Tissue Research. 347: 155-75. PMID 21626289 DOI: 10.1007/s00441-011-1189-3  1
2011 Toma I, St Laurent G, McCaffrey TA. Toward knowing the whole human: next-generation sequencing for personalized medicine. Personalized Medicine. 8: 483-491. PMID 29783338 DOI: 10.2217/pme.11.27  1
2011 Zhaorigetu S, Yang Z, Toma I, McCaffrey TA, Hu CA. Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells. The Journal of Biological Chemistry. 286: 27389-98. PMID 21646352 DOI: 10.1074/jbc.M110.210245  1
2011 Dwivedi RS, Herman JG, McCaffrey TA, Raj DS. Beyond genetics: epigenetic code in chronic kidney disease. Kidney International. 79: 23-32. PMID 20881938 DOI: 10.1038/ki.2010.335  1
2011 Toma I, St. Laurent G, McCaffrey TA. Toward knowing the whole human: Next-generation sequencing for personalized medicine Personalized Medicine. 8: 483-491. DOI: 10.2217/pme.11.27  1
2010 Kluk BJ, Fu Y, Formolo TA, Zhang L, Hindle AK, Man YG, Siegel RS, Berg PE, Deng C, McCaffrey TA, Fu SW. BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer. International Journal of Biological Sciences. 6: 513-24. PMID 20877436  1
2010 Fu Y, Lian Y, Kim KS, Zhang L, Hindle AK, Brody F, Siegel RS, McCaffrey TA, Fu SW. BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer. Journal of Cancer. 1: 54-62. PMID 20842225  1
2010 St Laurent G, Hammell N, McCaffrey TA. A LINE-1 component to human aging: do LINE elements exact a longevity cost for evolutionary advantage? Mechanisms of Ageing and Development. 131: 299-305. PMID 20346965 DOI: 10.1016/j.mad.2010.03.008  1
2009 McCaffrey TA. TGF-beta signaling in atherosclerosis and restenosis. Frontiers in Bioscience (Scholar Edition). 1: 236-45. PMID 19482699  1
2009 Yang Z, Gagarin D, St Laurent G, Hammell N, Toma I, Hu CA, Iwasa A, McCaffrey TA. Cardiovascular inflammation and lesion cell apoptosis: a novel connection via the interferon-inducible immunoproteasome. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1213-9. PMID 19443843 DOI: 10.1161/ATVBAHA.109.189407  1
2007 Yang Z, Gagarin D, Ramezani A, Hawley RG, McCaffrey TA. Resistance to fas-induced apoptosis in cells from human atherosclerotic lesions: elevated Bcl-XL inhibits apoptosis and caspase activation. Journal of Vascular Research. 44: 483-94. PMID 17657164 DOI: 10.1159/000106466  1
2007 Cahan P, Rovegno F, Mooney D, Newman JC, St Laurent G, McCaffrey TA. Meta-analysis of microarray results: challenges, opportunities, and recommendations for standardization. Gene. 401: 12-8. PMID 17651921 DOI: 10.1016/j.gene.2007.06.016  1
2005 Cahan P, Ahmad AM, Burke H, Fu S, Lai Y, Florea L, Dharker N, Kobrinski T, Kale P, McCaffrey TA. List of lists-annotated (LOLA): a database for annotation and comparison of published microarray gene lists. Gene. 360: 78-82. PMID 16140476 DOI: 10.1016/j.gene.2005.07.008  1
2005 Gagarin D, Yang Z, Butler J, Wimmer M, Du B, Cahan P, McCaffrey TA. Genomic profiling of acquired resistance to apoptosis in cells derived from human atherosclerotic lesions: potential role of STATs, cyclinD1, BAD, and Bcl-XL. Journal of Molecular and Cellular Cardiology. 39: 453-65. PMID 16005468 DOI: 10.1016/j.yjmcc.2005.01.015  1
2004 Bonecini-Almeida MG, Ho JL, Boéchat N, Huard RC, Chitale S, Doo H, Geng J, Rego L, Lazzarini LC, Kritski AL, Johnson WD, McCaffrey TA, Silva JR. Down-modulation of lung immune responses by interleukin-10 and transforming growth factor beta (TGF-beta) and analysis of TGF-beta receptors I and II in active tuberculosis. Infection and Immunity. 72: 2628-34. PMID 15102771 DOI: 10.1128/IAI.72.5.2628-2634.2004  1
2004 Abuljadayel IS, Afghan RK, McCaffrey TA, Lundergan C, Hawley TS, Hawley RG, Dhoot GJ. SCID repopulating cells derived from unmobilised adult human peripheral blood. Current Medical Research and Opinion. 20: 87-100. PMID 14741077 DOI: 10.1185/030079903125002766  1
2003 Marko NF, Dieffenbach PB, Yan G, Ceryak S, Howell RW, McCaffrey TA, Hu VW. Does metabolic radiolabeling stimulate the stress response? Gene expression profiling reveals differential cellular responses to internal beta vs. external gamma radiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1470-86. PMID 12890701 DOI: 10.1096/fj.02-1194com  1
2002 Faisal Khan KM, Laurie GW, McCaffrey TA, Falcone DJ. Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 expression. The Journal of Biological Chemistry. 277: 13778-86. PMID 11827968 DOI: 10.1074/jbc.M111290200  1
2000 Du B, Fu C, Kent KC, Bush H, Schulick AH, Kreiger K, Collins T, McCaffrey TA. Elevated Egr-1 in human atherosclerotic cells transcriptionally represses the transforming growth factor-β Type II receptor Journal of Biological Chemistry. 275: 39039-39047. PMID 10982796 DOI: 10.1074/jbc.M005159200  1
2000 McCaffrey TA, Fu C, Du B, Eksinar S, Kent KC, Harry B, Kreiger K, Rosengart T, Cybulsky MI, Silverman ES, Collins T. High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis Journal of Clinical Investigation. 105: 653-662. PMID 10712437  1
2000 Kaiura TL, Itoh H, Kubaska SM, McCaffrey TA, Liu B, Kent KC. The effect of growth factors, cytokines, and extracellular matrix proteins on fibronectin production in human vascular smooth muscle cells Journal of Vascular Surgery. 31: 577-584. PMID 10709072  1
2000 McCaffrey TA. TGF-βs and TGF-β receptors in atherosclerosis Cytokine and Growth Factor Reviews. 11: 103-114. PMID 10708958 DOI: 10.1016/S1359-6101(99)00034-9  1
2000 Yan Z, Subbaramaiah K, Camilli T, Zhang F, Tanabe T, McCaffrey TA, Dannenberg AJ, Weksler BB. Benzo[a]pyrene induces the transcription of cyclooxygenase-2 in vascular smooth muscle cells. Evidence for the involvement of extracellular signal- regulated kinase and NF-κB Journal of Biological Chemistry. 275: 4949-4955. PMID 10671533 DOI: 10.1074/jbc.275.7.4949  1
2000 Batuman O, Akman HO, McCaffrey TA, Zhang H, Siddiqui MAQ, Smith ELP. Response to hypoxia involves smad proteins in human endothelial cells Blood. 96.  1
1999 McCaffrey TA, Du B, Fu C, Bray PJ, Sanborn TA, Deutsch E, Tarazona N, Shaknovitch A, Newman G, Patterson C, Bush HL. The expression of TGF-β receptors in human atherosclerosis: Evidence for acquired resistance to apoptosis due to receptor imbalance Journal of Molecular and Cellular Cardiology. 31: 1627-1642. PMID 10471347 DOI: 10.1006/jmcc.1999.0999  1
1999 Shaknovich A, Forman ST, Parikh MA, Deutsch E, Bergman GW, McCaffrey TA, Newman GC, Tarazona N, Sanborn TA. Novel distal occluder washout method for prevention of no-reflow during stenting of saphenous vein grafts Catheterization and Cardiovascular Interventions. 47: 397-403. PMID 10470466 DOI: 10.1002/(SICI)1522-726X(199908)47:4<397::AID-CCD3>3.0.CO;2-M  1
1999 Bray PJ, Du B, Mejia VM, Hao SC, Deutsch E, Fu C, Wilson RC, Hanauske-Abel H, McCaffrey TA. Glucocorticoid resistance caused by reduced expression of the glucocorticoid receptor in cells from human vascular lesions. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 1180-9. PMID 10323768  1
1998 Sutaria PM, Ohebshalom M, McCaffrey TA, Vaughan ED, Felsen D. Transforming growth factor-β receptor types I and II are expressed in renal tubules and are increased after chronic unilateral ureteral obstruction Life Sciences. 62: 1965-1972. PMID 9619846 DOI: 10.1016/S0024-3205(98)00166-0  1
1997 McCaffrey TA, Du B, Consigli S, Szabo P, Bray PJ, Hartner L, Weksler BB, Sanborn TA, Bergman G, Bush HL. Genomic instability in the type II TGF-β1 receptor gene in atherosclerotic and restenotic vascular cells Journal of Clinical Investigation. 100: 2182-2188. PMID 9410894  1
1996 Leng L, Du B, Consigli S, McCaffrey TA. Translocation of protein kinase C-δ by PDGF in cultured vascular smooth muscle cells: Inhibition by TGF-β1 Artery. 22: 140-154. PMID 8893972  1
1996 Wright EJ, McCaffrey TA, Robertson AP, Vaughan ED, Felsen D. Chronic unilateral ureteral obstruction is associated with interstitial fibrosis and tubular expression of transforming growth factor-β Laboratory Investigation. 74: 528-537. PMID 8780170  1
1995 McCaffrey TA, Consigli S, Du B, Falcone DJ, Sanborn TA, Spokojny AM, Bush HL. Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions: Conversion from an antiproliferative to profibrotic response to TGF-β1 Journal of Clinical Investigation. 96: 2667-2675. PMID 8675633  1
1995 McCaffrey TA, Pomerantz KB, Sanborn TA, Spokojny AM, Du B, Park MH, Folk JE, Lamberg A, Kivirikko KI, Falcone DJ, Mehta SB, Hanauske-Abel HM. Specific inhibition of eIF-5A and collagen hydroxylation by a single agent: Antiproliferative and fibrosuppressive effects on smooth muscle cells from human coronary arteries Journal of Clinical Investigation. 95: 446-455. PMID 7860726  1
1995 Donovan MJ, Miranda RC, Kraemer R, McCaffrey TA, Tessarollo L, Mahadeo D, Sharif S, Kaplan DR, Tsoulfas P, Parada L. Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injury. The American Journal of Pathology. 147: 309-24. PMID 7639328  1
1995 Falcone DJ, McCaffrey TA, Mathew J, McAdam K, Borth W. THP-1 macrophage membrane-bound plasmin activity is up-regulated by transforming growth factor-β1 via increased expression of urokinase and the urokinase receptor Journal of Cellular Physiology. 164: 334-343. PMID 7622580 DOI: 10.1002/jcp.1041640214  1
1994 Falcone DJ, Borth W, McCaffrey TA, Mathew J, McAdam K. Regulation of macrophage receptor-bound plasmin by autoproteolysis Journal of Biological Chemistry. 269: 32660-32666. PMID 7528219  1
1994 McCaffrey TA, Falcone DJ, Borth W, Weksler BB. α2-Macroglobulin/transforming growth factor-β1 interactions. Modulation by heparin-like molecules and effects on vascular smooth muscle cells Annals of the New York Academy of Sciences. 737: 368-382. PMID 7524408 DOI: 10.1111/j.1749-6632.1994.tb44324.x  1
1994 Mccaffrey TA, Falcone DJ, Vicente D, Du B, Consigli S, Borth W. Protection of transforming growth factor-β1 activity by heparin and fucoidan Journal of Cellular Physiology. 159: 51-59. PMID 7511146 DOI: 10.1002/jcp.1041590108  1
1993 Falcone DJ, McCaffrey TA, Haimovitz-Friedman A, Vergilio JA, Nicholson AC. Macrophage and foam cell release of matrix-bound growth factors: Role of plasminogen activation Journal of Biological Chemistry. 268: 11951-11958. PMID 8505319  1
1993 McCaffrey TA, Falcone DJ. Evidence for an age-related dysfunction in the antiproliferative response to transforming growth factor-β in vascular smooth muscle cells Molecular Biology of the Cell. 4: 315-322. PMID 8387357  1
1993 Falcone DJ, McCaffrey TA, Haimovitz-Friedman A, Garcia M. Transforming growth factor-β1 stimulates macrophage urokinase expression and release of matrix-bound basic fibroblast growth factor Journal of Cellular Physiology. 155: 595-605. PMID 7684044  1
1992 McCaffrey TA, Falcone DJ, Du B. Transforming growth factor-β1 is a heparin-binding protein: Identification of putative heparin-binding regions and isolation of heparins with varying affinity for TGF-β Journal of Cellular Physiology. 152: 430-440. PMID 1639873  1
1992 McCaffrey TA, Falcone DJ, Borth W, Brayton CF, Weksler BB. Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia Biochemical and Biophysical Research Communications. 184: 773-781. PMID 1315533 DOI: 10.1016/0006-291X(92)90657-7  1
1991 Falcone DJ, McCaffrey TA, Vergiliot JA. Stimulation of macrophage urokinase expression by polyanions is protein kinase C-dependent and requires protein and RNA synthesis Journal of Biological Chemistry. 266: 22726-22732. PMID 1658006  1
1989 McCaffrey TA, Czaja JA. Diverse effects of estradiol-17 beta: concurrent suppression of appetite, blood pressure and vascular reactivity in conscious, unrestrained animals. Physiology & Behavior. 45: 649-57. PMID 2756058 DOI: 10.1016/0031-9384(89)90086-3  1
1989 McCaffrey TA, Falcone DJ, Brayton CF, Agarwal LA, Welt FGP, Weksler BB. Transforming growth factor-β activity is potentiated by heparin via dissociation of the transforming growth factor-β/α2-macroglobulin inactive complex Journal of Cell Biology. 109: 441-448. PMID 2473082  1
1988 McCaffrey TA, Nicholson AC, Szabo PE, Weksler ME, Weksler BB. Aging and arteriosclerosis. The increased proliferation of arterial smooth muscle cells isolated from old rats is associated with increased platelet-derived growth factor-like activity Journal of Experimental Medicine. 167: 163-174. PMID 3335829  1
1988 McCaffrey TA, Agarwal LA, Weksler BB. A rapid fluorometric DNA assay for the measurement of cell density and proliferation in vitro In Vitro Cellular and Developmental Biology - Animal. 24: 247-252. PMID 3280545  1
1985 Czaja JA, Butera PC, McCaffrey TA. Duration of hormonal deprivation: influences on physiological and behavioral responsiveness to estradiol. Hormones and Behavior. 19: 52-63. PMID 3979970 DOI: 10.1016/0018-506X(85)90005-4  1
1983 Czaja JA, Butera PC, McCaffrey TA. Independent effects of estradiol on water and food intake. Behavioral Neuroscience. 97: 210-20. PMID 6849684 DOI: 10.1037//0735-7044.97.2.210  1
1983 Czaja JA, McCaffrey TA, Butera PC. Effects of female hormonal condition on body weight of male partners: dependence on testicular factors. Behavioral Neuroscience. 97: 984-93. PMID 6686056 DOI: 10.1037//0735-7044.97.6.984  1
1980 Mitchell DS, Wigodsky HS, Peel HH, McCaffrey TA. Operant conditioning permits voluntary, noninvasive measurement of blood pressure in conscious, unrestrained baboons (Papio cynocephalus) Behavior Research Methods &Amp; Instrumentation. 12: 492-498. DOI: 10.3758/BF03201822  1
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