Relja Popovic, Ph.D. - Publications

Affiliations: 
2008 Loyola University Chicago, Chicago, IL, United States 
Area:
Molecular Biology

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Nabet B, Ó Broin P, Reyes JM, Shieh K, Lin CY, Will CM, Popovic R, Ezponda T, Bradner JE, Golden AA, Licht JD. Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape. Cell Reports. 12: 1300-13. PMID 26279576 DOI: 10.1016/j.celrep.2015.06.078  0.68
2015 Kumar K, Raza SS, Knab LM, Chow CR, Kwok B, Bentrem DJ, Popovic R, Ebine K, Licht JD, Munshi HG. GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1. Scientific Reports. 5: 9489. PMID 25807524 DOI: 10.1038/srep09489  0.68
2015 Zhou Z, Gao J, Popovic R, Wolniak K, Parimi V, Winter JN, Licht JD, Chen YH. Strong expression of EZH2 and accumulation of trimethylated H3K27 in diffuse large B-cell lymphoma independent of cell of origin and EZH2 codon 641 mutation. Leukemia & Lymphoma. 1-7. PMID 25651430 DOI: 10.3109/10428194.2015.1006220  0.68
2014 Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC, Hua Y, Bulic M, Jiang Y, Carrara M, Calogero RA, et al. Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation. Plos Genetics. 10: e1004566. PMID 25188243 DOI: 10.1371/journal.pgen.1004566  0.68
2013 Béguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SN, Wang L, Ezponda T, Martinez-Garcia E, Zhang H, Zheng Y, Verma SK, McCabe MT, et al. EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell. 23: 677-92. PMID 23680150 DOI: 10.1016/j.ccr.2013.04.011  0.68
2012 Zheng Y, Sweet SM, Popovic R, Martinez-Garcia E, Tipton JD, Thomas PM, Licht JD, Kelleher NL. Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3. Proceedings of the National Academy of Sciences of the United States of America. 109: 13549-54. PMID 22869745 DOI: 10.1073/pnas.1205707109  0.68
2012 Popovic R, Licht JD. Emerging epigenetic targets and therapies in cancer medicine. Cancer Discovery. 2: 405-13. PMID 22588878 DOI: 10.1158/2159-8290.CD-12-0076  0.68
2011 Popovic R, Licht JD. MEK and MAF in myeloma therapy. Blood. 117: 2300-2. PMID 21350059 DOI: 10.1182/blood-2011-01-327262  0.68
2011 Martinez-Garcia E, Popovic R, Min DJ, Sweet SM, Thomas PM, Zamdborg L, Heffner A, Will C, Lamy L, Staudt LM, Levens DL, Kelleher NL, Licht JD. The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood. 117: 211-20. PMID 20974671 DOI: 10.1182/blood-2010-07-298349  0.68
2010 Cierpicki T, Risner LE, Grembecka J, Lukasik SM, Popovic R, Omonkowska M, Shultis DD, Zeleznik-Le NJ, Bushweller JH. Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. Nature Structural & Molecular Biology. 17: 62-8. PMID 20010842 DOI: 10.1038/nsmb.1714  0.68
2009 Popovic R, Riesbeck LE, Velu CS, Chaubey A, Zhang J, Achille NJ, Erfurth FE, Eaton K, Lu J, Grimes HL, Chen J, Rowley JD, Zeleznik-Le NJ. Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization. Blood. 113: 3314-22. PMID 19188669 DOI: 10.1182/blood-2008-04-154310  0.68
2008 Erfurth FE, Popovic R, Grembecka J, Cierpicki T, Theisler C, Xia ZB, Stuart T, Diaz MO, Bushweller JH, Zeleznik-Le NJ. MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression. Proceedings of the National Academy of Sciences of the United States of America. 105: 7517-22. PMID 18483194 DOI: 10.1073/pnas.0800090105  0.68
2006 Santillan DA, Theisler CM, Ryan AS, Popovic R, Stuart T, Zhou MM, Alkan S, Zeleznik-Le NJ. Bromodomain and histone acetyltransferase domain specificities control mixed lineage leukemia phenotype. Cancer Research. 66: 10032-9. PMID 17047066 DOI: 10.1158/0008-5472.CAN-06-2597  0.68
2005 Xia ZB, Popovic R, Chen J, Theisler C, Stuart T, Santillan DA, Erfurth F, Diaz MO, Zeleznik-Le NJ. The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 14028-33. PMID 16169901 DOI: 10.1073/pnas.0506464102  0.68
2005 Popovic R, Zeleznik-Le NJ. MLL: how complex does it get? Journal of Cellular Biochemistry. 95: 234-42. PMID 15779005 DOI: 10.1002/jcb.20430  0.68
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