Richard N. Kitsis - Publications

Affiliations: 
Cell Biology Yeshiva University, New York, NY, United States 
Area:
Cell Biology, Endocrinology Biology

113/158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Kitsis RN, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w  0.356
2022 McKimpson WM, Kitsis RN. Inducing and measuring apoptotic cell death in mouse pancreatic β-cells and in isolated islets. Star Protocols. 3: 101287. PMID 35719268 DOI: 10.1016/j.xpro.2022.101287  0.75
2021 McKimpson WM, Chen Y, Irving JA, Zheng M, Weinberger J, Tan WLW, Tiang Z, Jagger AM, Chua SC, Pessin JE, Foo RS, Lomas DA, Kitsis RN. Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes. Developmental Cell. PMID 33667344 DOI: 10.1016/j.devcel.2021.02.011  0.747
2021 Chelko SP, Keceli G, Carpi A, Doti N, Agrimi J, Asimaki A, Beti CB, Miyamoto M, Amat-Codina N, Bedja D, Wei AC, Murray B, Tichnell C, Kwon C, Calkins H, ... ... Kitsis RN, et al. Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy. Science Translational Medicine. 13. PMID 33597260 DOI: 10.1126/scitranslmed.abf0891  0.354
2021 Nam YJ, Mani K, Ashton AW, Peng CF, Krishnamurthy B, Hayakawa Y, Lee P, Korsmeyer SJ, Kitsis RN. Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Molecular Cell. 81: 638. PMID 33545060 DOI: 10.1016/j.molcel.2021.01.018  0.684
2020 Chen F, Amgalan D, Kitsis RN, Pessin JE, Feng D. ATG16L1 autophagy pathway regulates BAX protein levels and programmed cell death. The Journal of Biological Chemistry. PMID 32848017 DOI: 10.1074/Jbc.Ra120.013999  0.465
2020 Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, Liang FG, Corbalan JJ, Lee J, Chen Y, Karagiannis GS, Sanchez LR, Liang H, Narayanagari SR, Mitchell K, ... ... Kitsis RN, et al. A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy. Nature Cancer. 1: 315-328. PMID 32776015 DOI: 10.1038/S43018-020-0039-1  0.477
2020 Templin AT, Schmidt CR, Hogan MF, Esser N, Kitsis RN, Hull RL, Zraika S, Kahn SE. 2042-P: Loss of Apoptosis Repressor with Caspase Recruitment Domain Promotes High-Fat Diet Induced Hyperglycemia In Vivo Diabetes. 69. DOI: 10.2337/Db20-2042-P  0.358
2019 Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, et al. Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop Circulation. 140: 1205-1216. PMID 31769940 DOI: 10.1161/Circulationaha.119.040551  0.318
2019 Del Re DP, Amgalan D, Linkermann A, Liu Q, Kitsis RN. Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease. Physiological Reviews. 99: 1765-1817. PMID 31364924 DOI: 10.1152/Physrev.00022.2018  0.5
2019 Amgalan D, Kitsis RN. A mouse model for the most common form of heart failure. Nature. 568: 324-325. PMID 30980035 DOI: 10.1038/D41586-019-00983-4  0.301
2019 Garner TP, Amgalan D, Reyna DE, Li S, Kitsis RN, Gavathiotis E. Small-molecule allosteric inhibitors of BAX. Nature Chemical Biology. PMID 30718816 DOI: 10.1038/S41589-018-0223-0  0.403
2018 Kitsis RN, Riquelme JA, Lavandero S. Heart Disease and Cancer. Circulation. 138: 692-695. PMID 30359137 DOI: 10.1161/Circulationaha.118.033907  0.304
2018 Feng D, Amgalan D, Singh R, Wei J, Wen J, Wei TP, McGraw TE, Kitsis RN, Pessin JE. SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy. The Journal of Clinical Investigation. PMID 30102258 DOI: 10.1172/Jci99217  0.464
2018 Corbalan JJ, Kitsis RN. RCAN1-Calcineurin Axis and the Set-Point for Myocardial Damage During Ischemia-Reperfusion. Circulation Research. 122: 796-798. PMID 29700078 DOI: 10.1161/Circresaha.118.312787  0.385
2018 Riascos-Bernal DF, Sibinga NES, Kitsis RN. PDCD5 says no to NO. Proceedings of the National Academy of Sciences of the United States of America. PMID 29666279 DOI: 10.1073/Pnas.1804491115  0.314
2018 Kushnir A, Santulli G, Reiken SR, Coromilas E, Godfrey SJ, Brunjes DL, Colombo PC, Yuzefpolskaya M, Sokol SI, Kitsis RN, Marks AR. Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure. Circulation. PMID 29593014 DOI: 10.1161/Circulationaha.117.032703  0.309
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Kitsis RN, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.453
2018 Chen Y, Lee J, Zheng M, Paulino V, Garcia C, Matute JM, Li H, Kaludercic N, Owusu-Ansah E, Cuervo AM, Kitsis RN. Abstract 117: Regulation of Cardiac Mitochondrial Function by Chaperone Mediated Autophagy Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.117  0.367
2017 Hazan RB, Suyama K, Yao J, Liang H, Benard O, Loudig OD, Amgalan D, McKimpson WM, Phillips GR, Segall JE, Wang Y, Fineberg S, Norton L, Kitsis RN. An Akt3 splice variant lacking the serine 472 phosphorylation site promotes apoptosis and suppresses mammary tumorigenesis. Cancer Research. PMID 29038347 DOI: 10.1158/0008-5472.Can-15-1462  0.772
2017 Amgalan D, Pekson R, Kitsis RN. Troponin release following brief myocardial ischemia: apoptosis versus necrosis. Jacc. Basic to Translational Science. 2: 118-121. PMID 29034357 DOI: 10.1016/J.Jacbts.2017.03.008  0.352
2017 Amgalan D, Chen Y, Kitsis RN. Death Receptor Signaling in the Heart: Cell Survival, Apoptosis, and Necroptosis. Circulation. 136: 743-746. PMID 28827219 DOI: 10.1161/Circulationaha.117.029566  0.516
2017 Yanamandala M, Zhu W, Garry DJ, Kamp TJ, Hare JM, Jun HW, Yoon YS, Bursac N, Prabhu SD, Dorn GW, Bolli R, Kitsis RN, Zhang J. Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering. Journal of the American College of Cardiology. 70: 766-775. PMID 28774384 DOI: 10.1016/J.Jacc.2017.06.012  0.345
2017 McKimpson WM, Zheng M, Chua SC, Pessin JE, Kitsis RN. ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes. Scientific Reports. 7: 7019. PMID 28765602 DOI: 10.1038/S41598-017-07107-W  0.76
2017 Templin AT, Samarasekera T, Meier DT, Hogan MF, Mellati M, Crow MT, Kitsis RN, Zraika S, Hull RL, Kahn SE. Apoptosis Repressor with Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation. Diabetes. PMID 28729244 DOI: 10.2337/Db16-1352  0.431
2017 Moslehi J, Amgalan D, Kitsis RN. Grounding Cardio-Oncology in Basic and Clinical Science. Circulation. 136: 3-5. PMID 28674089 DOI: 10.1161/Circulationaha.117.025393  0.322
2017 Shires SE, Kitsis RN, Gustafsson ÅB. Beyond Mitophagy: The Diversity and Complexity of Parkin Function. Circulation Research. 120: 1234-1236. PMID 28408450 DOI: 10.1161/Circresaha.116.310179  0.357
2017 McKimpson WM, Kitsis RN. A New Role for the ER Unfolded Protein Response Mediator ATF6: Induction of a Generalized Antioxidant Program. Circulation Research. 120: 759-761. PMID 28254796 DOI: 10.1161/Circresaha.117.310577  0.737
2017 Stanley RF, Piszczatowski RT, Bartholdy B, Mitchell K, McKimpson WM, Narayanagari S, Walter D, Todorova TI, Hirsch C, Makishima H, Will B, McMahon C, Gritsman K, Maciejewski JP, Kitsis RN, et al. A myeloid tumor suppressor role for NOL3. The Journal of Experimental Medicine. PMID 28232469 DOI: 10.1084/Jem.20162089  0.751
2017 Hammerling BC, Najor RH, Cortez MQ, Shires SE, Leon LJ, Gonzalez ER, Boassa D, Phan S, Thor A, Jimenez RE, Li H, Kitsis RN, Dorn Ii GW, Sadoshima J, Ellisman MH, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nature Communications. 8: 14050. PMID 28134239 DOI: 10.1038/Ncomms14050  0.395
2016 Nah J, Fernández ÁF, Kitsis RN, Levine B, Sadoshima J. Does Autophagy Mediate Cardiac Myocyte Death During Stress? Circulation Research. 119: 893-5. PMID 27688304 DOI: 10.1161/Circresaha.116.309765  0.485
2016 Murphy E, Ardehali H, Balaban RS, DiLisa F, Dorn GW, Kitsis RN, Otsu K, Ping P, Rizzuto R, Sack MN, Wallace D, Youle RJ. Mitochondrial Function, Biology, and Role in Disease: A Scientific Statement From the American Heart Association. Circulation Research. 118: 1960-91. PMID 27126807 DOI: 10.1161/Res.0000000000000104  0.34
2016 Shirakabe A, Fritzky L, Saito T, Zhai P, Miyamoto S, Gustafsson ÅB, Kitsis RN, Sadoshima J. Evaluating mitochondrial autophagy in the mouse heart. Journal of Molecular and Cellular Cardiology. 92: 134-139. PMID 26868976 DOI: 10.1016/J.Yjmcc.2016.02.007  0.335
2015 McKimpson WM, Yuan Z, Zheng M, Crabtree JS, Libutti SK, Kitsis RN. The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth. Plos One. 10: e0145792. PMID 26709830 DOI: 10.1371/Journal.Pone.0145792  0.742
2015 Chen H, Ruiz PD, McKimpson WM, Novikov L, Kitsis RN, Gamble MJ. MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype. Molecular Cell. 59: 719-31. PMID 26300260 DOI: 10.1016/J.Molcel.2015.07.011  0.743
2015 Song M, Gong G, Burelle Y, Gustafsson ÅB, Kitsis RN, Matkovich SJ, Dorn GW. Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts. Circulation Research. 117: 346-51. PMID 26038571 DOI: 10.1161/Circresaha.117.306859  0.384
2015 Maejima Y, Chen Y, Isobe M, Gustafsson ÅB, Kitsis RN, Sadoshima J. Recent progress in research on molecular mechanisms of autophagy in the heart. American Journal of Physiology. Heart and Circulatory Physiology. 308: H259-68. PMID 25398984 DOI: 10.1152/Ajpheart.00711.2014  0.424
2015 Dorn GW, Kitsis RN. The mitochondrial dynamism-mitophagy-cell death interactome: multiple roles performed by members of a mitochondrial molecular ensemble. Circulation Research. 116: 167-82. PMID 25323859 DOI: 10.1161/Circresaha.116.303554  0.36
2015 Chen H, Ruiz PD, McKimpson W, Novikov L, Kitsis RN, Gamble MJ. Abstract 1267: The senescence-associated secretory phenotype requires the histone variant macroH2A1 and is antagonized by ATM in a novel ER stress response Cancer Research. 75: 1267-1267. DOI: 10.1158/1538-7445.Am2015-1267  0.755
2014 Kung G, Dai P, Deng L, Kitsis RN. A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis. Cell Death and Differentiation. 21: 634-44. PMID 24440909 DOI: 10.1038/Cdd.2013.195  0.694
2013 Davis J, Kwong JQ, Kitsis RN, Molkentin JD. Apoptosis repressor with a CARD domain (ARC) restrains Bax-mediated pathogenesis in dystrophic skeletal muscle. Plos One. 8: e82053. PMID 24312627 DOI: 10.1371/Journal.Pone.0082053  0.385
2013 Yang Y, Rodriguez JE, Kitsis RN. A microRNA links prolactin to peripartum cardiomyopathy. The Journal of Clinical Investigation. 123: 1925-7. PMID 23619357 DOI: 10.1172/Jci69286  0.325
2013 Whelan RS, Konstantinidis K, Xiao RP, Kitsis RN. Cardiomyocyte life-death decisions in response to chronic β-adrenergic signaling. Circulation Research. 112: 408-10. PMID 23371896 DOI: 10.1161/Circresaha.113.300805  0.785
2013 Park M, Vatner SF, Yan L, Gao S, Yoon S, Lee GJ, Xie LH, Kitsis RN, Vatner DE. Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload. Basic Research in Cardiology. 108: 324. PMID 23277091 DOI: 10.1007/S00395-012-0324-Y  0.398
2013 McKimpson WM, Weinberger J, Czerski L, Zheng M, Crow MT, Pessin JE, Chua SC, Kitsis RN. The apoptosis inhibitor ARC alleviates the ER stress response to promote β-cell survival. Diabetes. 62: 183-93. PMID 22933109 DOI: 10.2337/Db12-0504  0.797
2013 Whelan RS, Konstantinidis K, Xiao RP, Kitsis RN. Erratum: Cardiomyocyte life-death decisions in response to chronic β-adrenergic signaling (Circulation Research (2013) 112 (408-410) DOI: 10.1161/CIRCRESAHA.113.300805) Circulation Research. 112. DOI: 10.1161/Res.0B013E31829C46A1  0.763
2013 James MK, Kitsis RN. Abstract 1729: Mitochondrial necrosis pathway drives tumor progression. Cancer Research. 73: 1729-1729. DOI: 10.1158/1538-7445.Am2013-1729  0.471
2012 Gavrilov S, Nührenberg TG, Ashton AW, Peng CF, Moore JC, Konstantinidis K, Mummery CL, Kitsis RN. Tbx6 is a determinant of cardiac and neural cell fate decisions in multipotent P19CL6 cells. Differentiation; Research in Biological Diversity. 84: 176-84. PMID 22721678 DOI: 10.1016/J.Diff.2012.04.007  0.598
2012 Konstantinidis K, Whelan RS, Kitsis RN. Mechanisms of cell death in heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1552-62. PMID 22596221 DOI: 10.1161/Atvbaha.111.224915  0.814
2012 Konstantinidis K, Kitsis RN. Cardiovascular biology: Escaped DNA inflames the heart. Nature. 485: 179-80. PMID 22575953 DOI: 10.1038/485179A  0.374
2012 Whelan RS, Konstantinidis K, Wei AC, Chen Y, Reyna DE, Jha S, Yang Y, Calvert JW, Lindsten T, Thompson CB, Crow MT, Gavathiotis E, Dorn GW, O'Rourke B, Kitsis RN. Bax regulates primary necrosis through mitochondrial dynamics. Proceedings of the National Academy of Sciences of the United States of America. 109: 6566-71. PMID 22493254 DOI: 10.1073/Pnas.1201608109  0.806
2012 Dorn GW, Kitsis RN. Programmed cardiomyocyte death in heart disease Muscle. 1: 423-446. DOI: 10.1016/B978-0-12-381510-1.00031-4  0.412
2011 Zaiman AL, Damico R, Thoms-Chesley A, Files DC, Kesari P, Johnston L, Swaim M, Mozammel S, Myers AC, Halushka M, El-Haddad H, Shimoda LA, Peng CF, Hassoun PM, Champion HC, ... Kitsis RN, et al. A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension. Circulation. 124: 2533-42. PMID 22082675 DOI: 10.1161/Circulationaha.111.034512  0.381
2011 Medina-Ramirez CM, Goswami S, Smirnova T, Bamira D, Benson B, Ferrick N, Segall J, Pollard JW, Kitsis RN. Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis, and chemoresistance. Cancer Research. 71: 7705-15. PMID 22037876 DOI: 10.1158/0008-5472.Can-11-2192  0.77
2011 Feng D, Tang Y, Kwon H, Zong H, Hawkins M, Kitsis RN, Pessin JE. High-fat diet-induced adipocyte cell death occurs through a cyclophilin D intrinsic signaling pathway independent of adipose tissue inflammation. Diabetes. 60: 2134-43. PMID 21734017 DOI: 10.2337/Db10-1411  0.364
2011 Kung G, Konstantinidis K, Kitsis RN. Programmed necrosis, not apoptosis, in the heart. Circulation Research. 108: 1017-36. PMID 21493924 DOI: 10.1161/Circresaha.110.225730  0.727
2011 Kung G, McKimpson W, Kitsis RN. NOL3 (nucleolar protein 3 (apoptosis repressor with CARD domain)) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/44736  0.77
2011 Medina-Ramirez CM, Gowasmi S, Smirnova T, Bamira D, Condeelis J, Segall J, Pollard JW, Kitsis RN. Abstract 4695: Apoptosis inhibitor ARC as a novel mediator of breast tumorigenesis, metastasis and chemoresistance Cancer Research. 71: 4695-4695. DOI: 10.1158/1538-7445.Am2011-4695  0.773
2010 Kitsis RN, Molkentin JD. Apoptotic cell death "Nixed" by an ER-mitochondrial necrotic pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 9031-2. PMID 20448198 DOI: 10.1073/Pnas.1003827107  0.467
2010 Wu L, Nam YJ, Kung G, Crow MT, Kitsis RN. Induction of the apoptosis inhibitor ARC by Ras in human cancers. The Journal of Biological Chemistry. 285: 19235-45. PMID 20392691 DOI: 10.1074/Jbc.M110.114892  0.759
2010 Whelan RS, Kaplinskiy V, Kitsis RN. Cell death in the pathogenesis of heart disease: mechanisms and significance. Annual Review of Physiology. 72: 19-44. PMID 20148665 DOI: 10.1146/Annurev.Physiol.010908.163111  0.818
2009 Park M, Shen YT, Gaussin V, Heyndrickx GR, Bartunek J, Resuello RR, Natividad FF, Kitsis RN, Vatner DE, Vatner SF. Apoptosis predominates in nonmyocytes in heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 297: H785-91. PMID 19465551 DOI: 10.1152/Ajpheart.00310.2009  0.441
2008 Mercier I, Vuolo M, Jasmin JF, Medina CM, Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP, Kitsis RN. ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer Cell Cycle. 7: 1640-1647. PMID 18469522 DOI: 10.4161/Cc.7.11.5979  0.428
2008 Kitsis RN, Narula J. Introduction-cell death in heart failure. Heart Failure Reviews. 13: 107-9. PMID 18214673 DOI: 10.1007/S10741-008-9080-3  0.507
2007 Foo RS, Nam YJ, Ostreicher MJ, Metzl MD, Whelan RS, Peng CF, Ashton AW, Fu W, Mani K, Chin SF, Provenzano E, Ellis I, Figg N, Pinder S, Bennett MR, ... ... Kitsis RN, et al. Regulation of p53 tetramerization and nuclear export by ARC. Proceedings of the National Academy of Sciences of the United States of America. 104: 20826-31. PMID 18087040 DOI: 10.1073/Pnas.0710017104  0.767
2007 Whelan RS, Mani K, Kitsis RN. Nipping at cardiac remodeling. The Journal of Clinical Investigation. 117: 2751-3. PMID 17909620 DOI: 10.1172/Jci33706  0.787
2007 Kitsis RN, Peng CF, Cuervo AM. Eat your heart out. Nature Medicine. 13: 539-41. PMID 17479097 DOI: 10.1038/Nm0507-539  0.35
2007 Foo RS, Chan LK, Kitsis RN, Bennett MR. Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2. The Journal of Biological Chemistry. 282: 5529-35. PMID 17142834 DOI: 10.1074/Jbc.M609046200  0.453
2007 Nam YJ, Mani K, Wu L, Peng CF, Calvert JW, Foo RS, Krishnamurthy B, Miao W, Ashton AW, Lefer DJ, Kitsis RN. The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant. The Journal of Biological Chemistry. 282: 5522-8. PMID 17142452 DOI: 10.1074/Jbc.M609186200  0.726
2005 Li J, Scherl A, Medina F, Frank PG, Kitsis RN, Tanowitz HB, Sotgia F, Lisanti MP. Impaired phagocytosis in caveolin-1 deficient macrophages. Cell Cycle (Georgetown, Tex.). 4: 1599-607. PMID 16205123 DOI: 10.4161/Cc.4.11.2117  0.376
2005 Tarzami ST, Calderon TM, Deguzman A, Lopez L, Kitsis RN, Berman JW. MCP-1/CCL2 protects cardiac myocytes from hypoxia-induced apoptosis by a G(alphai)-independent pathway. Biochemical and Biophysical Research Communications. 335: 1008-16. PMID 16102724 DOI: 10.1016/J.Bbrc.2005.07.168  0.44
2005 Pajvani UB, Trujillo ME, Combs TP, Iyengar P, Jelicks L, Roth KA, Kitsis RN, Scherer PE. Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy. Nature Medicine. 11: 797-803. PMID 15965483 DOI: 10.1038/Nm1262  0.372
2005 Mercier I, Vuolo M, Madan R, Xue X, Levalley AJ, Ashton AW, Jasmin JF, Czaja MT, Lin EY, Armstrong RC, Pollard JW, Kitsis RN. ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell Death and Differentiation. 12: 682-6. PMID 15861191 DOI: 10.1038/Sj.Cdd.4401631  0.381
2005 Foo RS, Mani K, Kitsis RN. Death begets failure in the heart. The Journal of Clinical Investigation. 115: 565-71. PMID 15765138 DOI: 10.1172/Jci24569  0.398
2005 Kitsis RN, Mann DL. Apoptosis and the heart: a decade of progress. Journal of Molecular and Cellular Cardiology. 38: 1-2. PMID 15623416 DOI: 10.1016/J.Yjmcc.2004.11.008  0.402
2004 Crow MT, Mani K, Nam YJ, Kitsis RN. The mitochondrial death pathway and cardiac myocyte apoptosis. Circulation Research. 95: 957-70. PMID 15539639 DOI: 10.1161/01.Res.0000148632.35500.D9  0.66
2004 Nam YJ, Mani K, Ashton AW, Peng CF, Krishnamurthy B, Hayakawa Y, Lee P, Korsmeyer SJ, Kitsis RN. Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Molecular Cell. 15: 901-12. PMID 15383280 DOI: 10.1016/J.Molcel.2004.08.020  0.727
2004 Young DA, Gavrilov S, Pennington CJ, Nuttall RK, Edwards DR, Kitsis RN, Clark IM. Expression of metalloproteinases and inhibitors in the differentiation of P19CL6 cells into cardiac myocytes. Biochemical and Biophysical Research Communications. 322: 759-65. PMID 15336529 DOI: 10.1016/J.Bbrc.2004.07.178  0.594
2003 Hayakawa Y, Chandra M, Miao W, Shirani J, Brown JH, Dorn GW, Armstrong RC, Kitsis RN. Inhibition of Cardiac Myocyte Apoptosis Improves Cardiac Function and Abolishes Mortality in the Peripartum Cardiomyopathy of Gαq Transgenic Mice Circulation. 108: 3036-3041. PMID 14638549 DOI: 10.1161/01.Cir.0000101920.72665.58  0.439
2003 Tarzami ST, Miao W, Mani K, Lopez L, Factor SM, Berman JW, Kitsis RN. Opposing effects mediated by the chemokine receptor CXCR2 on myocardial ischemia-reperfusion injury: recruitment of potentially damaging neutrophils and direct myocardial protection. Circulation. 108: 2387-92. PMID 14568904 DOI: 10.1161/01.Cir.0000093192.72099.9A  0.379
2003 Mukherjee S, Belbin TJ, Spray DC, Iacobas DA, Weiss LM, Kitsis RN, Wittner M, Jelicks LA, Scherer PE, Ding A, Tanowitz HB. Microarray analysis of changes in gene expression in a murine model of chronic chagasic cardiomyopathy. Parasitology Research. 91: 187-96. PMID 12910413 DOI: 10.1007/S00436-003-0937-Z  0.335
2003 Wencker D, Chandra M, Nguyen K, Miao W, Garantziotis S, Factor SM, Shirani J, Armstrong RC, Kitsis RN. A mechanistic role for cardiac myocyte apoptosis in heart failure Journal of Clinical Investigation. 111: 1497-1504. PMID 12750399 DOI: 10.1172/Jci17664  0.455
2003 Huang H, Petkova SB, Cohen AW, Bouzahzah B, Chan J, Zhou JN, Factor SM, Weiss LM, Krishnamachary M, Mukherjee S, Wittner M, Kitsis RN, Pestell RG, Lisanti MP, Albanese C, et al. Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis. Infection and Immunity. 71: 2859-67. PMID 12704159 DOI: 10.1128/Iai.71.5.2859-2867.2003  0.342
2003 Mani K, Kitsis RN. Myocyte apoptosis: programming ventricular remodeling. Journal of the American College of Cardiology. 41: 761-4. PMID 12628719 DOI: 10.1016/S0735-1097(02)02958-3  0.334
2003 Lee P, Sata M, Lefer DJ, Factor SM, Walsh K, Kitsis RN. Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 284: H456-63. PMID 12414449 DOI: 10.1152/Ajpheart.00777.2002  0.653
2003 Cohen AW, Park DS, Woodman SE, Williams TM, Chandra M, Shirani J, Pereira de Souza A, Kitsis RN, Russell RG, Weiss LM, Tang B, Jelicks LA, Factor SM, Shtutin V, Tanowitz HB, et al. Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts. American Journal of Physiology. Cell Physiology. 284: C457-74. PMID 12388077 DOI: 10.1152/Ajpcell.00380.2002  0.36
2002 Woodman SE, Park DS, Cohen AW, Cheung MW, Chandra M, Shirani J, Tang B, Jelicks LA, Kitsis RN, Christ GJ, Factor SM, Tanowitz HB, Lisanti MP. Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade. The Journal of Biological Chemistry. 277: 38988-97. PMID 12138167 DOI: 10.1074/Jbc.M205511200  0.39
2002 Peng CF, Wei Y, Levsky JM, McDonald TV, Childs G, Kitsis RN. Microarray analysis of global changes in gene expression during cardiac myocyte differentiation. Physiological Genomics. 9: 145-55. PMID 12045295 DOI: 10.1152/Physiolgenomics.00027.2002  0.367
2002 Tarzami ST, Cheng R, Miao W, Kitsis RN, Berman JW. Chemokine expression in myocardial ischemia: MIP-2 dependent MCP-1 expression protects cardiomyocytes from cell death. Journal of Molecular and Cellular Cardiology. 34: 209-21. PMID 11851360 DOI: 10.1006/Jmcc.2001.1503  0.421
2001 Gottlieb RA, Kitsis RN. Seeing death in the living Nature Medicine. 7: 1277-1278. PMID 11726959 DOI: 10.1038/Nm1201-1277  0.385
2001 Gao M, Fan S, Goldberg ID, Laterra J, Kitsis RN, Rosen EM. Hepatocyte Growth Factor/Scatter Factor Blocks the Mitochondrial Pathway of Apoptosis Signaling in Breast Cancer Cells Journal of Biological Chemistry. 276: 47257-47265. PMID 11571297 DOI: 10.1074/Jbc.M106791200  0.454
2001 Martins GA, Petkova SB, Machado FS, Kitsis RN, Weiss LM, Wittner M, Tanowitz HB, Silva JS. Fas-FasL interaction modulates nitric oxide production in Trypanosoma cruzi-infected mice Immunology. 103: 122-129. PMID 11380700 DOI: 10.1046/J.1365-2567.2001.01216.X  0.342
2001 Liu J, Lee P, Galbiati F, Kitsis RN, Lisanti MP. Caveolin-1 expression sensitizes fibroblastic and epithelial cells to apoptotic stimulation. American Journal of Physiology. Cell Physiology. 280: C823-35. PMID 11245599 DOI: 10.1152/Ajpcell.2001.280.4.C823  0.633
2001 Kitsis RN. Manipulating apoptosis in the myocardium Journal of Molecular and Cellular Cardiology. 33: A149. DOI: 10.1016/S0022-2828(01)90571-1  0.423
2000 Miao W, Luo Z, Kitsis RN, Walsh K. Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo Journal of Molecular and Cellular Cardiology. 32: 2397-2402. PMID 11113015 DOI: 10.1006/Jmcc.2000.1283  0.336
2000 Bueno OF, De Windt LJ, Tymitz KM, Witt SA, Kimball TR, Klevitsky R, Hewett TE, Jones SP, Lefer DJ, Peng CF, Kitsis RN, Molkentin JD. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. The Embo Journal. 19: 6341-50. PMID 11101507 DOI: 10.1093/Emboj/19.23.6341  0.374
2000 De Windt LJ, Lim HW, Taigen T, Wencker D, Condorelli G, Dorn GW, Kitsis RN, Molkentin JD. Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo. An apoptosis-independent model of dilated heart failure Circulation Research. 86: 255-263. PMID 10679475 DOI: 10.1161/01.Res.86.3.255  0.482
2000 Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against lschemia-reperfusion injury in mouse heart Circulation. 101: 660-667. PMID 10673259 DOI: 10.1161/01.Cir.101.6.660  0.383
1999 Albanese C, D'Amico M, Reutens AT, Fu M, Watanabe G, Lee RJ, Kitsis RN, Henglein B, Avantaggiati M, Somasundaram K, Thimmapaya B, Pestell RG. Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis Journal of Biological Chemistry. 274: 34186-34195. PMID 10567390 DOI: 10.1074/Jbc.274.48.34186  0.38
1999 Bialik S, Cryns VL, Drincic A, Miyata S, Wollowick AL, Srinivasan A, Kitsis RN. The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes Circulation Research. 85: 403-414. PMID 10473670 DOI: 10.1161/01.Res.85.5.403  0.473
1999 Morimoto T, Hasegawa K, Kaburagi S, Kakita T, Masutani H, Kitsis RN, Matsumori A, Sasayama S. GATA-5 is involved in leukemia inhibitory factor-responsive transcription of the β-myosin heavy chain gene in cardiac myocytes Journal of Biological Chemistry. 274: 12811-12818. PMID 10212267 DOI: 10.1074/Jbc.274.18.12811  0.339
1998 Xu Y, Bialik S, Jones BE, Iimuro Y, Kitsis RN, Srinivasan A, Brenner DA, Czaja MJ. NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis. The American Journal of Physiology. 275: C1058-66. PMID 9755059 DOI: 10.1152/Ajpcell.1998.275.4.C1058  0.324
1998 Shizukuda Y, Buttrick PM, Geenen DL, Borczuk AC, Kitsis RN, Sonnenblick EH. β-Adrenergic stimulation causes cardiocyte apoptosis: Influence of tachycardia and hypertrophy American Journal of Physiology - Heart and Circulatory Physiology. 275. PMID 9724301 DOI: 10.1152/Ajpheart.1998.275.3.H961  0.341
1998 Shizukuda Y, Sonnenblick E, Geenen D, Borczuk A, Kitsis R, Buttrick P. Chronic pressure overload is associated with cardiocyte apoptosis, but does not increase vulnerability to β-adrenergic mediated cardiocyte apoptosis Journal of the American College of Cardiology. 31: 176. DOI: 10.1016/S0735-1097(98)81407-1  0.375
1998 Shizukuda Y, Sonnenblick E, Geenen D, Borczuk A, Kitsis R, Buttrick P. β-Adrenergic stimulation induces cardiocyte apoptosis which is not mediated by an increase in heart rate Journal of the American College of Cardiology. 31: 177. DOI: 10.1016/S0735-1097(97)84474-9  0.39
1997 Hasegawa K, Lee SJ, Jobe SM, Markham BE, Kitsis RN. cis-Acting sequences that mediate induction of β-myosin heavy chain gene expression during left ventricular hypertrophy due to aortic constriction Circulation. 96: 3943-3953. PMID 9403619 DOI: 10.1161/01.Cir.96.11.3943  0.316
1997 Bialik S, Geenen DL, Sasson IE, Cheng R, Horner JW, Evans SM, Lord EM, Koch CJ, Kitsis RN. Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53 Journal of Clinical Investigation. 100: 1363-1372. PMID 9294101 DOI: 10.1172/Jci119656  0.436
1997 Hasegawa K, Meyers MB, Kitsis RN. Transcriptional coactivator p300 stimulates cell type-specific gene expression in cardiac myocytes Journal of Biological Chemistry. 272: 20049-20054. PMID 9242676 DOI: 10.1074/Jbc.272.32.20049  0.387
1996 Kitsis RN, Scheuer J. Functional significance of alterations in cardiac contractile protein isoforms Clinical Cardiology. 19: 9-18. PMID 8903533 DOI: 10.1002/Clc.4960190105  0.335
1996 Liu Y, Kitsis RN. Induction of DNA synthesis and apoptosis in cardiac myocytes by E1A oncoprotein Journal of Cell Biology. 133: 325-334. PMID 8609165 DOI: 10.1083/Jcb.133.2.325  0.384
1993 Buttrick PM, Kaplan ML, Kitsis RN, Leinwand LA. Distinct behavior of cardiac myosin heavy chain gene constructs in vivo: Discordance with in vitro results Circulation Research. 72: 1211-1217. PMID 8495550 DOI: 10.1161/01.Res.72.6.1211  0.301
1991 Kitsis RN, Buttrick PM, Mcnally EM, Kaplan ML, Leinwand LA. Hormonal modulation of a gene injected into rat heart in vivo Proceedings of the National Academy of Sciences of the United States of America. 88: 4138-4142. PMID 2034660 DOI: 10.1073/Pnas.88.10.4138  0.303
1990 Buttrick PM, Kass A, Kitsis RN, Kaplan ML, Leinwand LA. Behavior of genes directly injected into the rat heart in vivo Circulation Research. 70: 193-198. PMID 1309314 DOI: 10.1161/01.Res.70.1.193  0.31
Low-probability matches (unlikely to be authored by this person)
1995 Gardin JM, Siri FM, Kitsis RN, Edwards JG, Leinwand LA. Echocardiographic assessment of left ventricular mass and systolic function in mice. Circulation Research. 76: 907-14. PMID 7729009 DOI: 10.1161/01.Res.76.5.907  0.291
2012 Konstantinidis K, Lederer WJ, Rizzuto R, Kitsis RN. Mitofusin 2 joins the sarcoplasmic reticulum and mitochondria at the hip to sustain cardiac energetics. Circulation Research. 111: 821-3. PMID 22982869 DOI: 10.1161/Circresaha.112.277269  0.291
2011 Kaplinskiy V, Bennett MR, Kitsis RN. Cell death in the cardiovascular system Apoptosis: Physiology and Pathology. 295-312. DOI: 10.1017/CBO9780511976094.026  0.289
2011 Jha S, Kitsis RN. Myocardial Basis for Heart Failure. Role of Cell Death Heart Failure. 85-102. DOI: 10.1016/B978-1-4160-5895-3.10006-3  0.286
2005 Tanowitz HB, Huang H, Jelicks LA, Chandra M, Loredo ML, Weiss LM, Factor SM, Shtutin V, Mukherjee S, Kitsis RN, Christ GJ, Wittner M, Shirani J, Kisanuki YY, Yanagisawa M. Role of endothelin 1 in the pathogenesis of chronic chagasic heart disease. Infection and Immunity. 73: 2496-503. PMID 15784596 DOI: 10.1128/Iai.73.4.2496-2503.2005  0.285
2006 Kitsis RN, Jialal I. Limiting myocardial damage during acute myocardial infarction by inhibiting C-reactive protein. The New England Journal of Medicine. 355: 513-5. PMID 16885557 DOI: 10.1056/Nejmcibr063197  0.284
2018 Rocha AG, Franco A, Krezel AM, Rumsey JM, Alberti JM, Knight WC, Biris N, Zacharioudakis E, Janetka JW, Baloh RH, Kitsis RN, Mochly-Rosen D, Townsend RR, Gavathiotis E, Dorn GW. MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A. Science (New York, N.Y.). 360: 336-341. PMID 29674596 DOI: 10.1126/Science.Aao1785  0.283
2017 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, et al. Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nature Communications. 8: 578. PMID 28924218 DOI: 10.1038/S41467-017-00654-W  0.282
2007 Scheuer J, Kitsis RN. Edmund H. Sonnenblick, MD Circulation. 116: 2760-2761. DOI: 10.1161/Circulationaha.107.743039  0.282
2016 Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW. Correcting mitochondrial fusion by manipulating mitofusin conformations. Nature. PMID 27775718 DOI: 10.1038/Nature20156  0.28
2023 Qin D, Jia XF, Hanna A, Lee J, Pekson R, Elrod JW, Calvert JW, Frangogiannis NG, Kitsis RN. BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction. Journal of Molecular and Cellular Cardiology. PMID 37709008 DOI: 10.1016/j.yjmcc.2023.09.004  0.268
1993 van Hoeven KH, Kitsis RN, Katz SD, Factor SM. Peripartum versus idiopathic dilated cardiomyopathy in young women - a comparison of clinical, pathologic and prognostic features International Journal of Cardiology. 40: 57-65. PMID 8349367 DOI: 10.1016/0167-5273(93)90231-5  0.266
2016 Linkermann A, Konstantinidis K, Kitsis RN. Catch me if you can: Targeting the mitochondrial permeability transition pore in myocardial infarction Cell Death and Differentiation. 23: 1-2. DOI: 10.1038/Cdd.2015.151  0.264
1997 Evans SM, Bergeron M, Ferriero DM, Sharp FR, Hermeking H, Kitsis RN, Geenen DL, Bialik S, Lord EM, Koch CJ. Imaging hypoxia in diseased tissues. Advances in Experimental Medicine and Biology. 428: 595-603. PMID 9500104 DOI: 10.1007/978-1-4615-5399-1_84  0.259
1979 Eberhardt NL, Ring JC, Johnson LK, Latham KR, Apriletti JW, Kitsis RN, Baxter JD. Regulation of activity of chromatin receptors for thyroid hormone: Possible involvement of histone-like proteins Proceedings of the National Academy of Sciences of the United States of America. 76: 5005-5009. PMID 228271 DOI: 10.1073/Pnas.76.10.5005  0.254
2020 Tsai CH, Chang CY, Lin BZ, Wu YL, Wu MH, Lin LT, Huang WC, Holz JD, Sheu TJ, Lee JS, Kitsis RN, Tai PH, Lee YJ. Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27 -mediated growth delay. Aging Cell. e13288. PMID 33336885 DOI: 10.1111/acel.13288  0.246
2020 de Boer RA, Hulot JS, Gabriele Tocchetti C, Aboumsallem JP, Ameri P, Anker SD, Bauersachs J, Bertero E, Coats AAJ, Čelutkienė J, Chioncel O, Dodion P, Eschenhagen T, Farmakis D, Bayes-Genis A, ... ... Kitsis RN, et al. Common Mechanistic Pathways in Cancer and Heart Failure. European Journal of Heart Failure. PMID 33094495 DOI: 10.1002/ejhf.2029  0.246
2021 Jia XF, Liang FG, Kitsis RN. Multiple Cell Death Programs Contribute to Myocardial Infarction. Circulation Research. 129: 397-399. PMID 34292784 DOI: 10.1161/CIRCRESAHA.121.319584  0.232
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Kitsis RN, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.231
2022 Zacharioudakis E, Agianian B, Kumar Mv V, Biris N, Garner TP, Rabinovich-Nikitin I, Ouchida AT, Margulets V, Nordstrøm LU, Riley JS, Dolgalev I, Chen Y, Wittig AJH, Pekson R, Mathew C, ... ... Kitsis RN, et al. Modulating mitofusins to control mitochondrial function and signaling. Nature Communications. 13: 3775. PMID 35798717 DOI: 10.1038/s41467-022-31324-1  0.231
2016 Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, et al. Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise. Cell Metabolism. 23: 1078-1092. PMID 27304508 DOI: 10.1016/J.Cmet.2016.05.004  0.225
1998 Yang XU, Bialik S, Jones BE, Iimuro Y, Kitsis RN, Srinivasan A, Brenner DA, Czaja MJ. NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis American Journal of Physiology. 275.  0.219
1998 Xu Y, Bialik S, Jones BE, Iimuro Y, Kitsis RN, Srinivasan A, Brenner DA, Czaja MJ. NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis. American Journal of Physiology. Cell Physiology. 275: C1058-C1066. PMID 29585321 DOI: 10.1152/ajpcell.1998.275.4.C1058  0.218
2002 Mani K, Ashton AW, Kitsis RN. Taking the BAD out of adrenergic stimulation. Journal of Molecular and Cellular Cardiology. 34: 709-12. PMID 12099710 DOI: 10.1006/Jmcc.2002.2042  0.218
2023 Miao R, Jiang C, Chang WY, Zhang H, An J, Ho F, Chen P, Zhang H, Junqueira C, Amgalan D, Liang FG, Zhang J, Evavold CL, Hafner-Bratkovič I, Zhang Z, ... ... Kitsis RN, et al. Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis. Immunity. PMID 37924812 DOI: 10.1016/j.immuni.2023.10.004  0.199
2017 Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, et al. Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise. Cell Metabolism. 25: 218. PMID 28076763 DOI: 10.1016/J.Cmet.2016.12.003  0.195
2022 Lu P, Wu B, Feng X, Cheng W, Kitsis RN, Zhou B. Cardiac Myosin Heavy Chain Reporter Mice to Study Heart Development and Disease. Circulation Research. 101161CIRCRESAHA1223. PMID 35862119 DOI: 10.1161/CIRCRESAHA.122.321461  0.184
2023 Pekson R, Liang FG, Axelrod JL, Lee J, Qin D, Wittig AJH, Paulino VM, Zheng M, Peixoto PM, Kitsis RN. The mitochondrial ATP synthase is a negative regulator of the mitochondrial permeability transition pore. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303713120. PMID 38091291 DOI: 10.1073/pnas.2303713120  0.178
2021 Nakayama Y, Mukai N, Wang BF, Yang K, Patwari P, Kitsis RN, Yoshioka J. Txnip C247S mutation protects the heart against acute myocardial infarction. Journal of Molecular and Cellular Cardiology. PMID 33652022 DOI: 10.1016/j.yjmcc.2021.02.013  0.177
2008 Kitsis RN. Edmund H. Sonnenblick, MD (1932-2007). American Journal of Hypertension. 21: 241-2. PMID 18311119 DOI: 10.1038/Ajh.2007.79  0.173
2021 Moslehi J, Lichtman AH, Sharpe AH, Galluzzi L, Kitsis RN. Immune checkpoint inhibitor-associated myocarditis: manifestations and mechanisms. The Journal of Clinical Investigation. 131. PMID 33645548 DOI: 10.1172/JCI145186  0.172
2023 Casin KM, Bustamante M, Amanakis G, Sun J, Liu C, Kitsis RN, Murphy E. Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology. 183: 67-69. PMID 37696137 DOI: 10.1016/j.yjmcc.2023.09.003  0.172
2020 Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, Liang FG, Corbalan JJ, Lee J, Chen Y, Karagiannis GS, Sanchez LR, Liang H, Narayanagari S, Mitchell K, ... ... Kitsis RN, et al. A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy Nature Cancer. 1: 315-328. DOI: 10.1038/s43018-020-0039-1  0.171
2021 Templin AT, Schmidt C, Hogan MF, Esser N, Kitsis RN, Hull RL, Zraika S, Kahn SE. Loss of ARC worsens high fat diet-induced hyperglycemia in mice. The Journal of Endocrinology. PMID 34382577 DOI: 10.1530/JOE-20-0612  0.169
1996 McGrew MJ, Bogdanova N, Hasegawa K, Hughes SH, Kitsis RN, Rosenthal N. Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus Molecular and Cellular Biology. 16: 4524-4534. PMID 8754853 DOI: 10.1128/Mcb.16.8.4524  0.163
1988 Kitsis RN, Scheuer J. Correlations and dissociations between myosin isoenzymes and cardiac function Journal of Applied Cardiology. 3: 327-337.  0.161
2022 Murari A, Goparaju NSV, Rhooms SK, Hossain KFB, Liang FG, Garcia CJ, Osei C, Liu T, Li H, Kitsis RN, Patel R, Owusu-Ansah E. IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system. Science Advances. 8: eabl8716. PMID 35544578 DOI: 10.1126/sciadv.abl8716  0.158
2023 Axelrod JL, Pekson R, Kitsis RN. Introduction to review series: Regulated necrosis programs in heart disease. Journal of Molecular and Cellular Cardiology. 182: 73-74. PMID 37453667 DOI: 10.1016/j.yjmcc.2023.07.003  0.156
2023 Salloum FN, Tocchetti CG, Ameri P, Ardehali H, Asnani A, de Boer RA, Burridge P, Cabrera JÁ, de Castro J, Córdoba R, Costa A, Dent S, Engelbertsen D, Fernández-Velasco M, Fradley M, ... ... Kitsis RN, et al. Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: State-of-the-Art Review. Jacc. Cardiooncology. 5: 715-731. PMID 38205010 DOI: 10.1016/j.jaccao.2023.08.003  0.124
1992 Kitsis RN, Leinwand LA. Discordance between gene regulation in vitro and in vivo Gene Expression. 2: 313-318. PMID 1472867  0.123
2024 Liang FG, Moslehi J, Kitsis RN. Ponatinib-Induced Cardiomyocyte Toxicity: Dark Side of the Integrated Stress Response. Circulation Research. 134: 502-504. PMID 38422183 DOI: 10.1161/CIRCRESAHA.124.324164  0.12
2021 Sadoshima J, Kitsis RN, Sciarretta S. Editorial: Mitochondrial Dysfunction and Cardiovascular Diseases. Frontiers in Cardiovascular Medicine. 8: 645986. PMID 33585590 DOI: 10.3389/fcvm.2021.645986  0.119
2021 Lin MY, Chang YC, Wang SY, Yang MH, Chang CH, Hsiao M, Kitsis RN, Lee YJ. OncomiR miR-182-5p Enhances Radiosensitivity by Inhibiting the Radiation-Induced Antioxidant Effect through SESN2 in Head and Neck Cancer. Antioxidants (Basel, Switzerland). 10. PMID 34829679 DOI: 10.3390/antiox10111808  0.1
2000 Testa M, Ennezat PV, Vikstrom KL, Demopoulos L, Gentilucci M, Loperfido F, Fanelli R, Kitsis RN, Leinwand LA, LeJemtel TH. Modulation of vascular endothelial gene expression by physical training in patients with chronic heart failure. Italian Heart Journal : Official Journal of the Italian Federation of Cardiology. 1: 426-30. PMID 10929744  0.099
1996 Gardin JM, Siri F, Kitsis RN, Leinwand L. Intravascular Ultrasound Catheter Evaluation of the Left Ventricle in Mice: A Feasibility Study. Echocardiography (Mount Kisco, N.Y.). 13: 609-612. PMID 11442975 DOI: 10.1111/J.1540-8175.1996.Tb00941.X  0.076
Hide low-probability matches.