Yehiel Zick - Publications

Affiliations: 
Molecular Cell Biology Weizmann Institute of Science, Rehovot, Israel 
Area:
Molecular Biology, Cell Biology, Genetics

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Shatz-Azoulay H, Vinik Y, Isaac R, Kohler U, Lev S, Zick Y. The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice. Scientific Reports. 10: 7375. PMID 32355198 DOI: 10.1038/s41598-020-64371-z  0.88
2018 Bohari MH, Yu X, Kishor C, Patel B, Go RM, Eslampanah Seyedi HA, Vinik Y, Grice ID, Zick Y, Blanchard H. Corrigendum: Structure-Based Design of a Monosaccharide Ligand Targeting Galectin-8. Chemmedchem. 13: 2008. PMID 30230701 DOI: 10.1002/cmdc.201800582  0.88
2018 Bohari M, Yu X, Kishor C, Patel B, Go RM, Eslampanah Seyedi HA, Vinik Y, Grice ID, Zick Y, Blanchard H. Structure-based Design of a Monosaccharide Ligand Targeting Galectin-8. Chemmedchem. PMID 29926535 DOI: 10.1002/cmdc.201800224  0.88
2018 Herschkovitz A, Liu YF, Ilan E, Ronen D, Boura-Halfon S, Zick Y. Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance. The Journal of Biological Chemistry. 293: 7266. PMID 29752419 DOI: 10.1074/jbc.W118.003468  0.88
2018 Levy Y, Ronen D, Bershadsky AD, Zick Y. Sustained induction of ERK, protein kinase B, and p70 S6 kinase regulates cell spreading and formation of F-actin microspikes upon ligation of integrins by galectin-8, a mammalian lectin. The Journal of Biological Chemistry. 293: 7265. PMID 29752418 DOI: 10.1074/jbc.W118.003467  0.56
2018 Isaac R, Boura-Halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y. Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells. The Journal of Biological Chemistry. 293: 4577-4578. PMID 29572328 DOI: 10.1074/jbc.AAC118.002476  0.88
2017 Vinik Y, Shatz-Azoulay H, Hiram-Bab S, Kandel L, Gabet Y, Rivkin G, Zick Y. Ablation of the mammalian lectin galectin-8 induces bone defects in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29259034 DOI: 10.1096/fj.201700716R  0.88
2017 Isaac R, Vinik Y, Boura-Halfon S, Farack L, Streim S, Elhanany E, Kam Z, Zick Y. Prolonged Elimination of Negative Feedback Control Mechanisms Along the Insulin Signalling Pathway Impairs β Cell Function In Vivo. Diabetes. PMID 28424159 DOI: 10.2337/db16-0827  0.88
2016 Isaac R, Goldstein I, Furth N, Zilber N, Streim S, Boura-Halfon S, Elhanany E, Rotter V, Oren M, Zick Y. TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response. Cell Death and Differentiation. PMID 27740623 DOI: 10.1038/cdd.2016.108  0.88
2016 Bucris E, Beck A, Boura-Halfon S, Isaac R, Vinik Y, Rosenzweig T, Sampson S, Zick Y. Prolonged insulin treatment sensitizes apoptosis pathways in pancreatic beta cells. The Journal of Endocrinology. PMID 27411561 DOI: 10.1530/JOE-15-0505  0.88
2015 Beck A, Shatz-Azoulay H, Vinik Y, Isaac R, Boura-Halfon S, Zick Y. Nedd4 family interacting protein 1 (Ndfip1) promotes death of pancreatic beta cells. Biochemical and Biophysical Research Communications. 465: 851-6. PMID 26319551 DOI: 10.1016/j.bbrc.2015.08.099  1
2015 Vinik Y, Shatz-Azoulay H, Vivanti A, Hever N, Levy Y, Karmona R, Brumfeld V, Baraghithy S, Attar-Lamdar M, Boura-Halfon S, Bab I, Zick Y. The mammalian lectin galectin-8 induces RANKL expression, osteoclastogenesis, and bone mass reduction in mice. Elife. 4: e05914. PMID 25955862 DOI: 10.7554/eLife.05914  1
2013 Zachut M, Honig H, Striem S, Zick Y, Boura-Halfon S, Moallem U. Periparturient dairy cows do not exhibit hepatic insulin resistance, yet adipose-specific insulin resistance occurs in cows prone to high weight loss Journal of Dairy Science. 96: 5656-5669. PMID 23871373 DOI: 10.3168/jds.2012-6142  1
2013 Beck A, Vinik Y, Shatz-Azoulay H, Isaac R, Streim S, Jona G, Boura-Halfon S, Zick Y. Otubain 2 is a novel promoter of beta cell survival as revealed by siRNA high-throughput screens of human pancreatic islets. Diabetologia. 56: 1317-26. PMID 23515685 DOI: 10.1007/s00125-013-2889-x  1
2013 Isaac R, Boura-Halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y. Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells. The Journal of Biological Chemistry. 288: 5682-93. PMID 23275337 DOI: 10.1074/jbc.M112.408641  1
2012 Alberstein M, Zornitzki T, Zick Y, Knobler H. Hepatitis C core protein impairs insulin downstream signalling and regulatory role of IGFBP-1 expression Journal of Viral Hepatitis. 19: 65-71. PMID 22187946 DOI: 10.1111/j.1365-2893.2011.01447.x  1
2012 Gurevitch D, Shuster-Meiseles T, Nov O, Zick Y, Rudich A, Rudich Y. TiO2 nanoparticles induce insulin resistance in liver-derived cells both directly and via macrophage activation. Nanotoxicology. 6: 804-12. PMID 22007682 DOI: 10.3109/17435390.2011.625128  1
2011 Beck A, Isaac R, Lavelin I, Hart Y, Volberg T, Shatz-Azoulay H, Geiger B, Zick Y. An siRNA screen identifies transmembrane 7 superfamily member 3 (TM7SF3), a seven transmembrane orphan receptor, as an inhibitor of cytokine-induced death of pancreatic beta cells. Diabetologia. 54: 2845-55. PMID 21853325 DOI: 10.1007/s00125-011-2277-3  1
2010 Boura-Halfon S, Shuster-Meiseles T, Beck A, Petrovich K, Gurevitch D, Ronen D, Zick Y. A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1). Molecular Endocrinology (Baltimore, Md.). 24: 2179-92. PMID 20843941 DOI: 10.1210/me.2010-0072  1
2010 Gurevitch D, Boura-Halfon S, Isaac R, Shahaf G, Alberstein M, Ronen D, Lewis EC, Zick Y. Elimination of negative feedback control mechanisms along the insulin signaling pathway improves beta-cell function under stress. Diabetes. 59: 2188-97. PMID 20547979 DOI: 10.2337/db09-0890  1
2010 Jacob AI, Horovitz-Fried M, Aga-Mizrachi S, Brutman-Barazani T, Okhrimenko H, Zick Y, Brodie C, Sampson SR. The regulatory domain of protein kinase C delta positively regulates insulin receptor signaling. Journal of Molecular Endocrinology. 44: 155-69. PMID 19952103 DOI: 10.1677/JME-09-0119  1
2009 Boura-Halfon S, Zick Y. Serine kinases of insulin receptor substrate proteins. Vitamins and Hormones. 80: 313-49. PMID 19251043 DOI: 10.1016/S0083-6729(08)00612-2  1
2009 Boura-Halfon S, Zick Y. Phosphorylation of IRS proteins, insulin action, and insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 296: E581-91. PMID 18728222 DOI: 10.1152/ajpendo.90437.2008  1
2008 Shanik MH, Xu Y, Skrha J, Dankner R, Zick Y, Roth J. Insulin resistance and hyperinsulinemia: is hyperinsulinemia the cart or the horse? Diabetes Care. 31: S262-8. PMID 18227495 DOI: 10.2337/dc08-s264  1
2007 Naor D, Nedvetzki S, Walmsley M, Yayon A, Turley EA, Golan I, Caspi D, Sebban LE, Zick Y, Garin T, Karussis D, Assayag-Asherie N, Raz I, Weiss L, Slavin S, et al. CD44 involvement in autoimmune inflammations: the lesson to be learned from CD44-targeting by antibody or from knockout mice. Annals of the New York Academy of Sciences. 1110: 233-47. PMID 17911438 DOI: 10.1196/annals.1423.025  1
2007 Levkovitz Y, Ben-Shushan G, Hershkovitz A, Isaac R, Gil-Ad I, Shvartsman D, Ronen D, Weizman A, Zick Y. Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases. Molecular and Cellular Neurosciences. 36: 305-12. PMID 17728140 DOI: 10.1016/j.mcn.2007.05.009  1
2007 Eshkar Sebban L, Ronen D, Levartovsky D, Elkayam O, Caspi D, Aamar S, Amital H, Rubinow A, Golan I, Naor D, Zick Y, Golan I. The involvement of CD44 and its novel ligand galectin-8 in apoptotic regulation of autoimmune inflammation. Journal of Immunology (Baltimore, Md. : 1950). 179: 1225-35. PMID 17617615  1
2007 Herschkovitz A, Liu YF, Ilan E, Ronen D, Boura-Halfon S, Zick Y. Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance. The Journal of Biological Chemistry. 282: 18018-27. PMID 17446166 DOI: 10.1074/jbc.M610949200  1
2006 Levy Y, Auslender S, Eisenstein M, Vidavski RR, Ronen D, Bershadsky AD, Zick Y. It depends on the hinge: a structure-functional analysis of galectin-8, a tandem-repeat type lectin. Glycobiology. 16: 463-76. PMID 16501058 DOI: 10.1093/glycob/cwj097  1
2005 Arbel-Goren R, Levy Y, Ronen D, Zick Y. Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8. The Journal of Biological Chemistry. 280: 19105-14. PMID 15753078 DOI: 10.1074/jbc.M502060200  1
2005 Zick Y. Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe4. PMID 15671481 DOI: 10.1126/stke.2682005pe4  1
2004 Zick Y. Molecular basis of insulin action. Novartis Foundation Symposium. 262: 36-50; disucssion 50. PMID 15562822  1
2004 Zick Y. Uncoupling insulin signalling by serine/threonine phosphorylation: A molecular basis for insulin resistance Biochemical Society Transactions. 32: 812-816. PMID 15494022 DOI: 10.1042/BST0320812  1
2004 Liu YF, Herschkovitz A, Boura-Halfon S, Ronen D, Paz K, Leroith D, Zick Y. Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance. Molecular and Cellular Biology. 24: 9668-81. PMID 15485932 DOI: 10.1128/MCB.24.21.9668-9681.2004  1
2004 Storan MJ, Magnaldo T, Biol-N'Garagba MC, Zick Y, Key B. Expression and putative role of lactoseries carbohydrates present on NCAM in the rat primary olfactory pathway. The Journal of Comparative Neurology. 475: 289-302. PMID 15221946 DOI: 10.1002/cne.20167  1
2004 Zick Y, Eisenstein M, Goren RA, Hadari YR, Levy Y, Ronen D. Role of galectin-8 as a modulator of cell adhesion and cell growth. Glycoconjugate Journal. 19: 517-26. PMID 14758075 DOI: 10.1023/B:GLYC.0000014081.55445.af  1
2003 Zick Y. Role of Ser/Thr kinases in the uncoupling of insulin signaling International Journal of Obesity. 27. PMID 14704747 DOI: 10.1038/sj.ijo.0802503  1
2003 Kayser K, Dünnwald D, Kazmierczak B, Bullerdiek J, Kaltner H, Zick Y, André S, Gabius HJ. Chromosomal aberrations, profiles of expression of growth-related markers including galectins and environmental hazards in relation to the incidence of chondroid pulmonary hamartomas. Pathology, Research and Practice. 199: 589-98. PMID 14621194 DOI: 10.1078/0344-0338-00466  1
2003 Kayser K, Hoeft D, Hufnagl P, Caselitz J, Zick Y, André S, Kaltner H, Gabius HJ. Combined analysis of tumor growth pattern and expression of endogenous lectins as a prognostic tool in primary testicular cancer and its lung metastases Histology and Histopathology. 18: 771-779. PMID 12792889  1
2003 Nagy N, Legendre H, Engels O, André S, Kaltner H, Wasano K, Zick Y, Pector JC, Decaestecker C, Gabius HJ, Salmon I, Kiss R. Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting. Cancer. 97: 1849-58. PMID 12673710 DOI: 10.1002/cncr.11268  1
2003 Boura-Halfon S, Voliovitch H, Feinstein R, Paz K, Zick Y. Extracellular matrix proteins modulate endocytosis of the insulin receptor. The Journal of Biological Chemistry. 278: 16397-404. PMID 12594209 DOI: 10.1074/jbc.M212385200  1
2003 Levy Y, Ronen D, Bershadsky AD, Zick Y. Sustained induction of ERK, protein kinase B, and p70 S6 kinase regulates cell spreading and formation of F-actin microspikes upon ligation of integrins by galectin-8, a mammalian lectin. The Journal of Biological Chemistry. 278: 14533-42. PMID 12569102 DOI: 10.1074/jbc.M207380200  1
2003 Grimberg A, LeRoith D, Holly J, Zick Y, Laron Z, Pollak M, Ohlsson R, Carpentier JL, Thomas G, De Meyts P, Carbone D, Macauley V, Roberts C, Lonning's PE, Rosenfeld R, et al. Biology of IGF-I: Its interaction with insulin in health and malignant States Novartis Foundation Symposium No. 263 London, 13-16 October 2003 Pediatric Endocrinology Reviews. 1: 137-139.  1
2002 Wollina U, Graefe T, Feldrappe S, André S, Wasano K, Kaltner H, Zick Y, Gabius HJ. Galectin fingerprinting by immuno- and lectin histochemistry in cutaneous lymphoma Journal of Cancer Research and Clinical Oncology. 128: 103-110. PMID 11862481 DOI: 10.1007/s00432-001-0304-3  1
2002 Hemi R, Paz K, Wertheim N, Karasik A, Zick Y, Kanety H. Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins. The Journal of Biological Chemistry. 277: 8961-9. PMID 11779863 DOI: 10.1074/jbc.M109391200  1
2001 Zick Y. Insulin resistance: A phosphorylation-based uncoupling of insulin signaling Trends in Cell Biology. 11: 437-441. PMID 11684411 DOI: 10.1016/S0962-8924(01)02129-8  1
2001 Choufani G, Ghanooni R, Decaestecker C, Delbrouck K, Simon P, Schüring MP, Zick Y, Hassid S, Gabius HJ, Kiss R. Detection of macrophage migration inhibitory factor (MIF) in human cholesteatomas and functional implications of correlations to recurrence status and to expression of matrix metalloproteinases-3/9, retinoic acid receptor-β, and anti-apoptotic galectin-3 Laryngoscope. 111: 1656-1662. PMID 11568623  1
2001 Sheikholeslam-Zadeh R, Decaestecker C, Delbrouck C, Danguy A, Salmon I, Zick Y, Kaltner H, Hassid S, Gabius HJ, Kiss R, Choufani G. The levels of expression of galectin-3, but not of galectin-1 and galectin-8, correlate with apoptosis in human cholesteatomas Laryngoscope. 111: 1042-1047. PMID 11404618  1
2001 Simon P, Decaestecker C, Choufani G, Delbrouck C, Danguy A, Salmon I, Zick Y, Kaltner H, Hassid S, Gabius HJ, Kiss R, Darro F. The levels of retinoid RARβ receptors correlate with galectin-1, -3 and -8 expression in human cholesteatomas Hearing Research. 156: 1-9. PMID 11377877 DOI: 10.1016/S0378-5955(01)00230-1  1
2001 Levy Y, Arbel-Goren R, Hadari YR, Eshhar S, Ronen D, Elhanany E, Geiger B, Zick Y. Galectin-8 functions as a matricellular modulator of cell adhesion. The Journal of Biological Chemistry. 276: 31285-95. PMID 11371555 DOI: 10.1074/jbc.M100340200  1
2001 Karas M, Koval AP, Zick Y, LeRoith D. The insulin-like growth factor I receptor-induced interaction of insulin receptor substrate-4 and Crk-II Endocrinology. 142: 1835-1840. PMID 11316748 DOI: 10.1210/en.142.5.1835  1
2001 Le Roith D, Zick Y. Recent advances in our understanding of insulin action and insulin resistance Diabetes Care. 24: 588-597. PMID 11289486  1
2001 Liu YF, Paz K, Herschkovitz A, Alt A, Tennenbaum T, Sampson SR, Ohba M, Kuroki T, LeRoith D, Zick Y. Insulin stimulates PKCζ-mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins Journal of Biological Chemistry. 276: 14459-14465. PMID 11278339 DOI: 10.1074/jbc.m007281200  1
2000 Kayser K, Zink S, Schneider T, Dienemann H, André S, Kaltner H, Schüring MP, Zick Y, Gabius HJ. Benign metastasizing leiomyoma of the uterus: Documentation of clinical, immunohistochemical and lectin-histochemical data of ten cases Virchows Archiv. 437: 284-292. PMID 11037349 DOI: 10.1007/s004280000207  1
2000 Hadari YR, Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y. Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis. Journal of Cell Science. 113: 2385-97. PMID 10852818  1
2000 Paz K, Boura-Halfon S, Wyatt LS, LeRoith D, Zick Y. The juxtamembrane but not the carboxyl-terminal domain of the insulin receptor mediates insulin's metabolic functions in primary adipocytes and cultured hepatoma cells Journal of Molecular Endocrinology. 24: 419-432. PMID 10828835 DOI: 10.1677/JME.0.0240419  1
1999 Paz K, Liu YF, Shorer H, Hemi R, LeRoith D, Quan M, Kanety H, Seger R, Zick Y. Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function Journal of Biological Chemistry. 274: 28816-28822. PMID 10497255 DOI: 10.1074/jbc.274.40.28816  1
1998 Koval AP, Karas M, Zick Y, LeRoith D. Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth factor-I receptor-mediated signal transduction Journal of Biological Chemistry. 273: 14780-14787. PMID 9614078 DOI: 10.1074/jbc.273.24.14780  1
1998 Koval AP, Blakesley VA, Roberts CT, Zick Y, LeRoith D. Interaction in vitro of the product of the c-Crk-II proto-oncogene with the insulin-like growth factor I receptor Biochemical Journal. 330: 923-932. PMID 9480911  1
1998 Li SL, Termini J, Hayward A, Siddle K, Zick Y, Koval A, Leroith D, Fujita-Yamaguchi Y. The carboxyl-terminal domain of insulin-like growth factor-I receptor interacts with the insulin receptor and activates its protein tyrosine kinase Febs Letters. 421: 45-49. PMID 9462837 DOI: 10.1016/S0014-5793(97)01523-8  1
1997 Paz K, Hemi R, LeRoith D, Karasik A, Elhanany E, Kanety H, Zick Y. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation Journal of Biological Chemistry. 272: 29911-29918. PMID 9368067 DOI: 10.1074/jbc.272.47.29911  1
1997 Cohen J, Altaratz H, Zick Y, Klingmüller U, Neumann D. Phosphorylation of erythropoietin receptors in the endoplasmic reticulum by pervanadate-mediated inhibition of tyrosine phosphatases Biochemical Journal. 327: 391-397. PMID 9359406  1
1997 Hadari YR, Haring HU, Zick Y. p75, a member of the heat shock protein family, undergoes tyrosine phosphorylation in response to oxidative stress Journal of Biological Chemistry. 272: 657-662. PMID 8995309 DOI: 10.1074/jbc.272.1.657  1
1997 Hadari YR, Eisenstein M, Zakut R, Zick Y. Galectin-8: On the road from structure to functions Trends in Glycoscience and Glycotechnology. 9: 103-112.  1
1997 Paz K, Hemi R, LeRoith D, Karasik A, Kanety H, Zick Y. Molecular basis for insulin resistance: Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtaraembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation Experimental and Clinical Endocrinology and Diabetes. 105: 10.  1
1996 Biener Y, Feinstein R, Mayak M, Kaburagi Y, Kadowaki T, Zick Y. Annexin II is a novel player in insulin signal transduction: Possible association between annexin II phosphorylation and insulin receptor internalization Journal of Biological Chemistry. 271: 29489-29496. PMID 8910617 DOI: 10.1074/jbc.271.46.29489  1
1996 Paz K, Voliovitch H, Hadari YR, Roberts CT, LeRoith D, Zick Y. Interaction between the insulin receptor and its downstream effectors: Use of individually expressed receptor domains for structure/function analysis Journal of Biological Chemistry. 271: 6998-7003. PMID 8636129 DOI: 10.1074/jbc.271.12.6998  1
1995 Rosenblum K, Schul R, Meiri N, Hadari YR, Zick Y, Dudai Y. Modulation of protein tyrosine phosphorylation in rat insular cortex after conditioned taste aversion training. Proceedings of the National Academy of Sciences of the United States of America. 92: 1157-61. PMID 7862652 DOI: 10.1073/pnas.92.4.1157  1
1995 Hadari YR, Paz K, Dekel R, Mestrovic T, Accili D, Zick Y. Galectin-8. A new rat lectin, related to galectin-4 Journal of Biological Chemistry. 270: 3447-3453. PMID 7852431 DOI: 10.1074/jbc.270.7.3447  1
1995 Voliovitch H, Schindler DG, Hadari YR, Taylor SI, Accili D, Zick Y. Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region. The Journal of Biological Chemistry. 270: 18083-7. PMID 7629118 DOI: 10.1074/jbc.270.30.18083  1
1995 Seger R, Biener Y, Feinstein R, Hanoch T, Gazit A, Zick Y. Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-O-tetradecanoylphorbol-13-acetate (TPA) and insulin. Evidence for involvement of a TPA-stimulated protein-tyrosine kinase Journal of Biological Chemistry. 270: 28325-28330. PMID 7499332 DOI: 10.1074/jbc.270.47.28325  1
1994 Nadiv O, Shinitzky M, Manu H, Hecht D, Roberts CT, LeRoith D, Zick Y. Elevated protein tyrosine phosphatase activity and increased membrane viscosity are associated with impaired activation of the insulin receptor kinase in old rats Biochemical Journal. 298: 443-450. PMID 8135754  1
1994 Roach P, Zick Y, Formisano P, Accili D, Taylor SI, Gorden P. A novel human insulin receptor gene mutation uniquely inhibits insulin binding without impairing posttranslational processing Diabetes. 43: 1096-1102. PMID 8070609  1
1993 Hadari YR, Geiger B, Nadiv O, Sabanay I, Roberts CT, LeRoith D, Zick Y. Hepatic tyrosine-phosphorylated proteins identified and localized following in vivo inhibition of protein tyrosine phosphatases: effects of H2O2 and vanadate administration into rat livers Molecular and Cellular Endocrinology. 97: 9-17. PMID 8143908 DOI: 10.1016/0303-7207(93)90206-Y  1
1992 Hecht D, Zick Y. Selective inhibition of protein tyrosine phosphatase activities by H2O2 and vanadate In vitro Biochemical and Biophysical Research Communications. 188: 773-779. PMID 1445322 DOI: 10.1016/0006-291X(92)91123-8  1
1992 Hadari YR, Tzahar E, Nadiv O, Rothenberg P, Roberts CT, LeRoith D, Yarden Y, Zick Y. Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3′-kinase upon its association with pp185 (IRS-1) in intact rat livers Journal of Biological Chemistry. 267: 17483-17486. PMID 1381348  1
1992 Volberg T, Zick Y, Dror R, Sabanay I, Gilon C, Levitzki A, Geiger B. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. The Embo Journal. 11: 1733-42. PMID 1316270  1
1992 Nadiv O, Cohen O, Zick Y. Defects in insulin's signal transduction in old rat livers Endocrinology. 130: 1515-1524. PMID 1311243 DOI: 10.1210/en.130.3.1515  1
1992 Heffetz D, Rutter WJ, Zick Y. The insulinomimetic agents H2O2 and vanadate stimulate tyrosine phosphorylation of potential target proteins for the insulin receptor kinase in intact cells. The Biochemical Journal. 288: 631-5. PMID 1281409  1
1991 Bushkin I, Roth J, Heffetz D, Zick Y. pp75: A novel tyrosine-phosphorylated protein that heralds differentiation of HL-60 cells Journal of Biological Chemistry. 266: 11890-11895. PMID 2050685  1
1991 Heffetz D, Fridkin M, Zick Y. Generation and use of antibodies to phosphothreonine Methods in Enzymology. 201: 44-53. PMID 1943772  1
1991 Biener Y, Zick Y. Polylysine increases the number of insulin binding sites in soluble insulin receptor preparations Journal of Biological Chemistry. 266: 17369-17375. PMID 1894624  1
1991 Volberg T, Geiger B, Dror R, Zick Y. Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells. Cell Regulation. 2: 105-20. PMID 1650581  1
1990 Zick Y, Sagi-Eisenberg R. A combination of H2O2 and vanadate concomitantly stimulates protein tyrosine phosphorylation and polyphosphoinositide breakdown in different cell lines Biochemistry®. 29: 10240-10245. PMID 2176864  1
1990 Bushkin I, Zick Y. Alterations in insulin receptor kinase activity during differentiation of HL-60 cells Biochemical and Biophysical Research Communications. 172: 676-682. PMID 2173575 DOI: 10.1016/0006-291X(90)90727-5  1
1990 Heffetz D, Bushkin I, Dror R, Zick Y. The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells. The Journal of Biological Chemistry. 265: 2896-902. PMID 2154464  1
1990 Biener Y, Zick Y. Basic polycations activate the insulin receptor kinase and a tightly associated serine kinase European Journal of Biochemistry. 194: 243-250. PMID 1701386 DOI: 10.1111/j.1432-1033.1990.tb19449.x  1
1989 Seger R, Zick Y, Shaltiel S. Studying the structure of the intracellular moiety of the insulin receptor with a kinase-splitting membranal proteinase Embo Journal. 8: 435-440. PMID 2656255  1
1989 Sagi-Eisenberg R, Traub LM, Spiegel AM, Zick Y. Protein kinase C-mediated phosphorylation of retinal rod outer segment membrane proteins. Cellular Signalling. 1: 519-31. PMID 2641684 DOI: 10.1016/0898-6568(89)90036-3  1
1989 Heffetz D, Zick Y. H2O2 potentiates phosphorylation of novel putative substrates for the insulin receptor kinase in intact Fao cells Journal of Biological Chemistry. 264: 10126-10132. PMID 2542323  1
1989 Zick Y. The insulin receptor: Structure and functio Critical Reviews in Biochemistry and Molecular Biology. 24: 217-269. PMID 2541971 DOI: 10.3109/10409238909082554  1
1989 Heffetz D, Fridkin M, Zick Y. Antibodies directed against phosphothreonine residues as potent tools for studying protein phosphorylation European Journal of Biochemistry. 182: 343-348. PMID 2500341  1
1989 Shemer J, Adamo M, Raizada MK, Heffez D, Zick Y, LeRoith D. Insulin and IGF-I stimulate phosphorylation of their respective receptors in intact neuronal and glial cells in primary culture Journal of Molecular Neuroscience. 1: 137. DOI: 10.1007/BF02896897  1
1987 Zick Y, Spiegel AM, Sagi-Eisenberg R. Insulin-like growth factor I receptors in retinal rod outer segments. The Journal of Biological Chemistry. 262: 10259-64. PMID 2956255  1
1987 Shemer J, Adamo M, Wilson GL, Heffez D, Zick Y, LeRoith D. Insulin and insulin-like growth factor-I stimulate a common endogenous phosphoprotein substrate (pp185) in intact neuroblastoma cells Journal of Biological Chemistry. 262.  1
1986 Heffetz D, Zick Y. Receptor aggregation is necessary for activation of the soluble insulin receptor kinase Journal of Biological Chemistry. 261: 889-894. PMID 3510209  1
1986 Zick Y, Sagi-Eisenberg R, Pines M, Gierschik P, Spiegel AM. Multisite phosphorylation of the alpha subunit of transducin by the insulin receptor kinase and protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 83: 9294-7. PMID 3099281  1
1986 Zick Y. Regulation of the insulin receptor kinase activity Fernstrom Foundation Series. 43-57.  1
1985 Sasaki N, Rees-Jones RW, Zick Y, Nissley SP, Rechler MM. Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the β-subunit of type I insulin-like growth factor receptors of rat liver cells Journal of Biological Chemistry. 260: 9793-9804. PMID 2991263  1
1985 Zick Y, Grunberger G, Rees-Jones RW, Comi RJ. Use of tyrosine-containing polymers to characterize the substrate specificity of insulin and other hormone-stimulated tyrosine kinases European Journal of Biochemistry. 148: 177-182. PMID 2983990  1
1985 Whittaker J, Zick Y, Roth J, Taylor SI. Insulin-stimulated receptor phosphorylation appears normal in cultured Epstein-Barr virus-transformed lymphocyte cell lines derived from patients with extreme insulin resistance Journal of Clinical Endocrinology and Metabolism. 60: 381-386. PMID 2981245  1
1984 Zick Y, Rees-Jones RW, Taylor SI, Gorden P, Roth J. The role of antireceptor antibodies in stimulating phosphorylation of the insulin receptor Journal of Biological Chemistry. 259: 4396-4400. PMID 6538568  1
1984 Zick Y, Sasaki N, Rees-Jones RW, Grunberger G, Nissley SP, Rechler MM. Insulin-like growth factor-I (IGF-I) stimulates tyrosine kinase activity in purified receptors from a rat liver cell line Biochemical and Biophysical Research Communications. 119: 6-13. PMID 6322788 DOI: 10.1016/0006-291X(84)91610-3  1
1984 Grunberger G, Zick Y, Taylor SI, Gorden P. Tumor-promoting phorbol ester stimulates tyrosine phosphorylation in U-937 monocytes Proceedings of the National Academy of Sciences of the United States of America. 81: 2762-2766. PMID 6201862  1
1984 Grunberger G, Zick Y, Gorden P. Defect in phosphorylation of insulin receptors in cells from an insulin-resistant patient with normal insulin binding Science. 223: 932-934. PMID 6141638  1
1983 Grunberger G, Zick Y, Roth J, Gorden P. Protein kinase activity of the insulin receptor in human circulating and cultured mononuclear cells Biochemical and Biophysical Research Communications. 115: 560-566. PMID 6626204 DOI: 10.1016/S0006-291X(83)80181-8  1
1983 Zick Y, Rees-Jones RW, Grunberger G, Taylor SI, Moncada V, Gorden P, Roth J. The insulin-stimulated receptor kinase is a tyrosine-specific casein kinase European Journal of Biochemistry. 137: 631-637. PMID 6363065  1
1983 Rees-Jones RW, Hedo J, Zick Y, Roth J. Insulin-stimulated phosphorylation of the insulin receptor precursor Biochemical and Biophysical Research Communications. 116: 417-422. PMID 6360168 DOI: 10.1016/0006-291X(83)90539-9  1
1983 Zick Y, Whittaker J, Roth J. Insulin stimulated phosphorylation of its own receptor. Activation of a tyrosine specific protein kinase that is tightly associated with the receptor Journal of Biological Chemistry. 258: 3431-3434. PMID 6339486  1
1983 Zick Y, Kasuga M, Kahn CR, Roth J. Characterization of insulin-mediated phosphorylation of the insulin receptor in a cell-free system Journal of Biological Chemistry. 258: 75-80. PMID 6336757  1
1983 Zick Y, Grunberger G, Podskalny JM, Moncada V, Taylor SI, Gorden P, Roth J. Insulin stimulates phosphorylation of serine residues in soluble insulin receptors Biochemical and Biophysical Research Communications. 116: 1129-1135. PMID 6316966 DOI: 10.1016/S0006-291X(83)80260-5  1
1983 Zick Y, Cesla R, Shaltiel S. Viable mouse thymocytes as a model system for studying the onset of hormone-induced cellular refractoriness Bba - Molecular Cell Research. 762: 355-365. PMID 6299392 DOI: 10.1016/0167-4889(83)90090-3  1
1982 Zick Y, Cesla R, Shaltiel S. Exposure of thymocytes to a low temperature (4 degrees C) inhibits the onset of their hormone-induced cellular refractoriness Journal of Biological Chemistry. 257: 4253-4259. PMID 6279631  1
1982 Kasuga M, Zick Y, Blith DL, Karlsson FA, Häring HU, Kahn CR. Insulin stimulation of phosphorylation of the β subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine Journal of Biological Chemistry. 257: 9891-9894. PMID 6179940  1
1982 Kasuga M, Zick Y, Blithe DL, Crettaz M, Kahn CR. Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system Nature. 298: 667-669. PMID 6178977 DOI: 10.1038/298667a0  1
1982 Kasuga M, Zick Y, Blithe D. Insulin stimulates phosphorylation of both tyrosine and serine residues of the insulin receptor Diabetes. 31.  1
1980 Zick Y, Cesla R, Shaltiel S. Inhibiting the onset of hormone-induced desensitization of viable thymocytes by N(α)-tosyl-l-lysine chloromethyl ketone Proceedings of the National Academy of Sciences of the United States of America. 77: 5967-5971. PMID 6255472 DOI: 10.1073/pnas.77.10.5967  1
1979 Zick Y, Cesla R, Shaltiel S. cAMP-dependent protein kinase from mouse thymocytes. Localization, characterization, and evaluation of the physiological relevance of a massive cytosol to nucleus translocation Journal of Biological Chemistry. 254: 879-887. PMID 216683  1
1978 Zick Y, Cesla R, Shaltiel S. Non-hormonal burst in the level of cAMP caused by a 'temperature shock" to mouse thymocytes Febs Letters. 90: 239-242. PMID 208860 DOI: 10.1016/0014-5793(78)80376-7  1
1975 Zick Y, Goldblatt D, Bustin M. Exposure of histone F1 subfractions in chromatin Biochemical and Biophysical Research Communications. 65: 637-643. PMID 50068 DOI: 10.1016/S0006-291X(75)80194-X  1
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