Brian V. Geisbrecht - Publications

Affiliations: 
Cell and Molecular Biology University of Missouri - Kansas City, USA 
Area:
General Biophysics, Biochemistry, Bioinformatics Biology, Microbiology Biology

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Xu X, Lewis Marffy AL, Keightley A, McCarthy AJ, Geisbrecht BV. Group B Surface Protein β: Structural Characterization of a Complement Factor H-Binding Motif and Its Contribution to Immune Evasion. Journal of Immunology (Baltimore, Md. : 1950). PMID 35110419 DOI: 10.4049/jimmunol.2101078  0.361
2021 Savitt AG, Manimala S, White T, Fandaros M, Yin W, Duan H, Xu X, Geisbrecht BV, Rubenstein DA, Kaplan AP, Peerschke EI, Ghebrehiwet B. SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems. Frontiers in Immunology. 12: 767347. PMID 34804054 DOI: 10.3389/fimmu.2021.767347  0.377
2021 Pal I, Mishra N, Herrera AI, Dubey A, Arthanari H, Geisbrecht BV, Prakash O. 1H, 15N, and 13C backbone resonance assignments of the C4b-binding region from the S. aureus extracellular adherence protein. Biomolecular Nmr Assignments. PMID 33423171 DOI: 10.1007/s12104-020-10003-6  0.354
2021 Xu X, Zhang C, Denton DT, O'Connell D, Drolet DW, Geisbrecht BV. Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B. Journal of Immunology (Baltimore, Md. : 1950). PMID 33419768 DOI: 10.4049/jimmunol.2001260  0.36
2020 Glaza P, Ranaweera CB, Shiva S, Roy A, Geisbrecht BV, Schoenen FJ, Zolkiewski M. Repurposing p97 inhibitors for chemical modulation of the bacterial ClpB/DnaK bi-chaperone system. The Journal of Biological Chemistry. PMID 33187983 DOI: 10.1074/jbc.RA120.015413  0.304
2020 Velazhahan V, Glaza P, Herrera AI, Prakash O, Zolkiewski M, Geisbrecht BV, Schrick K. Dietary flavonoid fisetin binds human SUMO1 and blocks sumoylation of p53. Plos One. 15: e0234468. PMID 32530958 DOI: 10.1371/Journal.Pone.0234468  0.43
2020 Herdendorf TJ, Stapels DAC, Rooijakkers SHM, Geisbrecht BV. Local structural plasticity of the evasion protein EapH1 enables engagement with multiple neutrophil serine proteases. The Journal of Biological Chemistry. PMID 32303641 DOI: 10.1074/Jbc.Ra120.013601  0.461
2020 Joseph AM, Pohl AE, Ball TJ, Abram TG, Johnson DK, Geisbrecht BV, Shames SR. The metaeffector Lpg2505 (MesI) regulates SidI-mediated translation inhibition and novel glycosyl hydrolase activity. Infection and Immunity. PMID 32122942 DOI: 10.1128/Iai.00853-19  0.489
2020 El Qaidi S, Scott NE, Hays MP, Geisbrecht BV, Watkins S, Hardwidge PR. An intra-bacterial activity for a T3SS effector. Scientific Reports. 10: 1073. PMID 31974499 DOI: 10.1038/S41598-020-58062-Y  0.474
2020 Herdendorf TJ, Rooijakkers SHM, Geisbrecht BV. Crystal Structure of Human Cathepsin-G Inhibited by S. aureus EapH1 Journal of Biological Chemistry. DOI: 10.2210/Pdb6Vtm/Pdb  0.336
2020 Xu X, van Sorge N, van der Lans S, van Woudenbergh E, van Strijp J, McCarthy AJ, Geisbrecht B. Structural and Interaction Insight in Streptococcal beta C Proteins The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02495  0.351
2019 Ghebrehiwet B, Geisbrecht BV, Xu X, Savitt AG, Peerschke EIB. The C1q Receptors: Focus on gC1qR/p33 (C1qBP, p32, HABP-1). Seminars in Immunology. 101338. PMID 31744753 DOI: 10.1016/J.Smim.2019.101338  0.466
2019 Herdendorf TJ, Geisbrecht BV. Staphylococcus aureus evasion proteins EapH1 and EapH2: Residue-level investigation of an alternative binding motif for human neutrophil elastase. Archives of Biochemistry and Biophysics. 676: 108140. PMID 31622584 DOI: 10.1016/J.Abb.2019.108140  0.479
2019 Ramyar KX, Xu X, White NM, Keightley A, Geisbrecht BV. Expression, purification, and characterization of a human complement component C3 analog that lacks the C-terminal C345c domain. Journal of Immunological Methods. PMID 31319063 DOI: 10.1016/J.Jim.2019.07.005  0.433
2019 Herrera AI, Dubey A, Geisbrecht BV, Arthanari H, Prakash O. Backbone resonance assignments of innate immune evasion protein EapH2 from the S. aureus. Biomolecular Nmr Assignments. PMID 30729401 DOI: 10.1007/S12104-019-09880-3  0.471
2018 Herdendorf TJ, Geisbrecht BV. Investigation of Human Neutrophil Elastase Inhibition by Staphylococcus aureus EapH1: The Key Role Played by Arginine 89. Biochemistry. 57: 6888-6896. PMID 30461258 DOI: 10.1021/Acs.Biochem.8B01134  0.4
2018 Eisenbeis J, Saffarzadeh M, Peisker H, Jung P, Thewes N, Preissner KT, Herrmann M, Molle V, Geisbrecht BV, Jacobs K, Bischoff M. The Extracellular Adherence Protein Eap Is a DNA Binding Protein Capable of Blocking Neutrophil Extracellular Trap Formation. Frontiers in Cellular and Infection Microbiology. 8: 235. PMID 30038902 DOI: 10.3389/Fcimb.2018.00235  0.373
2018 Barta ML, Tachiyama S, Muthuramalingam M, Arizmendi O, Villanueva CE, Ramyar KX, Geisbrecht BV, Lovell S, Battaile KP, Picking WL, Picking WD. Using Disruptive Insertional Mutagenesis to Identify the In Situ Structure-Function Landscape of the Shigella Translocator Protein IpaB. Protein Science : a Publication of the Protein Society. PMID 29672980 DOI: 10.1002/Pro.3428  0.761
2018 Ploscariu NT, de Jong NWM, van Kessel KPM, van Strijp JAG, Geisbrecht BV. Identification and structural characterization of a novel myeloperoxidase inhibitor from Staphylococcus delphini. Archives of Biochemistry and Biophysics. PMID 29524428 DOI: 10.1016/J.Abb.2018.03.007  0.424
2018 Eng L, Garcia BL, Geisbrecht BV, Hanning A. Quantitative monitoring of two simultaneously binding species using Label-Enhanced surface plasmon resonance. Biochemical and Biophysical Research Communications. PMID 29427666 DOI: 10.1016/J.Bbrc.2018.02.040  0.682
2018 de Jong NWM, Vrieling M, Garcia BL, Koop G, Brettmann M, Aerts PC, Ruyken M, van Strijp JAG, Holmes M, Harrison EM, Geisbrecht BV, Rooijakkers SHM. Identification of a Staphylococcal Complement Inhibitor with broad host specificity in equid S. aureus strains. The Journal of Biological Chemistry. PMID 29414776 DOI: 10.1074/Jbc.Ra117.000599  0.715
2018 Herrera AI, Ploscariu NT, Geisbrecht BV, Prakash O. 1H, 15N, and 13C resonance assignments of the third domain from the S. aureus innate immune evasion protein Eap. Biomolecular Nmr Assignments. PMID 29372458 DOI: 10.1007/S12104-018-9804-9  0.439
2018 de Jong NWM, Ploscariu NT, Ramyar KX, Garcia BL, Herrera AI, Prakash O, Katz BB, Leidal KG, Nauseef WM, van Kessel KPM, van Strijp JAG, Geisbrecht BV. A Structurally Dynamic N-terminal Region Drives Function of the Staphylococcal Peroxidase Inhibitor (SPIN). The Journal of Biological Chemistry. PMID 29306874 DOI: 10.1074/Jbc.Ra117.000134  0.676
2017 Shrestha R, Huang G, Meekins DA, Geisbrecht BV, Li P. Mechanistic Insights into Dye-Decolorizing Peroxidase Revealed by Solvent Isotope and Viscosity Effects. Acs Catalysis. 7: 6352-6364. PMID 29308295 DOI: 10.1021/Acscatal.7B01861  0.368
2017 Stapels DAC, Woehl JL, Milder FJ, Tromp AT, van Batenburg AA, de Graaf WC, Broll SC, White NM, Rooijakkers SHM, Geisbrecht BV. Evidence for Multiple Modes of Neutrophil Serine Protease Recognition by the EAP Family of Staphylococcal Innate Immune Evasion Proteins. Protein Science : a Publication of the Protein Society. PMID 29114958 DOI: 10.1002/Pro.3342  0.54
2017 Ploscariu NT, Herrera AI, Jayanthi S, Suresh Kumar TK, Geisbrecht BV, Prakash O. Backbone and side-chain (1)H, (15)N, and (13)C resonance assignments of a novel Staphylococcal inhibitor of myeloperoxidase. Biomolecular Nmr Assignments. PMID 28815423 DOI: 10.1007/S12104-017-9764-5  0.415
2017 de Jong NWM, Ramyar KX, Guerra FE, Nijland R, Fevre C, Voyich JM, McCarthy AJ, Garcia BL, van Kessel KPM, van Strijp JAG, Geisbrecht BV, Haas PA. Immune evasion by a staphylococcal inhibitor of myeloperoxidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808028 DOI: 10.1073/Pnas.1707032114  0.709
2017 Wang G, Geisbrecht BV, Rueter C, Hardwidge PR. Enterotoxigenic Escherichia coli Flagellin Inhibits TNF-Induced NF-κB Activation in Intestinal Epithelial Cells. Pathogens (Basel, Switzerland). 6. PMID 28513540 DOI: 10.3390/Pathogens6020018  0.354
2017 Woehl JL, Ramyar KX, Katz BB, Walker JK, Geisbrecht BV. The structural basis for inhibition of the classical and lectin complement pathways by S. Aureus extracellular adherence protein. Protein Science : a Publication of the Protein Society. PMID 28512867 DOI: 10.1002/Pro.3195  0.481
2017 Huang G, Shrestha R, Jia K, Geisbrecht BV, Li P. Enantioselective Synthesis of Dilignol Model Compounds and Their Stereodiscrimination Study with a Dye-Decolorizing Peroxidase. Organic Letters. PMID 28326791 DOI: 10.1021/Acs.Orglett.7B00587  0.324
2017 Garcia BL, Skaff DA, Chatterjee A, Hanning A, Walker JK, Wyckoff GJ, Geisbrecht BV. Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics. Journal of Immunology (Baltimore, Md. : 1950). PMID 28298523 DOI: 10.4049/Jimmunol.1601932  0.799
2017 Papanastasiou M, Koutsogiannaki S, Sarigiannis Y, Geisbrecht BV, Ricklin D, Lambris JD. Structural Implications for the Formation and Function of the Complement Effector Protein iC3b. Journal of Immunology (Baltimore, Md. : 1950). PMID 28258193 DOI: 10.4049/Jimmunol.1601864  0.446
2016 Shrestha R, Chen X, Ramyar KX, Hayati Z, Carlson EA, Bossmann SH, Song L, Geisbrecht BV, Li P. Identification of Surface-Exposed Protein Radicals and A Substrate Oxidation Site in A-Class Dye-Decolorizing Peroxidase from Thermomonospora curvata. Acs Catalysis. 6: 8036-8047. PMID 29308294 DOI: 10.1021/Acscatal.6B01952  0.373
2016 Garcia BL, Zwarthoff SA, Rooijakkers SH, Geisbrecht BV. Novel Evasion Mechanisms of the Classical Complement Pathway. Journal of Immunology (Baltimore, Md. : 1950). 197: 2051-60. PMID 27591336 DOI: 10.4049/Jimmunol.1600863  0.715
2016 Woehl JL, Takahashi D, Herrera AI, Geisbrecht BV, Prakash O. (1)H, (15)N, and (13)C resonance assignments of Staphylococcus aureus extracellular adherence protein domain 4. Biomolecular Nmr Assignments. PMID 27372920 DOI: 10.1007/S12104-016-9688-5  0.487
2016 Bannantine JP, Lingle CK, Adam PR, Ramyar KX, McWhorter WJ, Stabel JR, Picking WD, Geisbrecht BV. NlpC/P60 Domain-Containing Proteins of Mycobacterium avium subspecies paratuberculosis that Differentially Bind and Hydrolyze Peptidoglycan. Protein Science : a Publication of the Protein Society. PMID 26799947 DOI: 10.1002/Pro.2884  0.407
2015 Georgoutsou-Spyridonos M, Ricklin D, Pratsinis H, Perivolioti E, Pirmettis I, Garcia BL, Geisbrecht BV, Foukas PG, Lambris JD, Mastellos DC, Sfyroera G. Attenuation of Staphylococcus aureus-Induced Bacteremia by Human Mini-Antibodies Targeting the Complement Inhibitory Protein Efb. Journal of Immunology (Baltimore, Md. : 1950). 195: 3946-58. PMID 26342032 DOI: 10.4049/Jimmunol.1500966  0.728
2015 Chen C, Shrestha R, Jia K, Gao PF, Geisbrecht BV, Bossmann SH, Shi J, Li P. Characterization of Dye-decolorizing Peroxidase (DyP) from Thermomonospora curvata Reveals Unique Catalytic Properties of A-type DyPs. The Journal of Biological Chemistry. 290: 23447-63. PMID 26205819 DOI: 10.1074/Jbc.M115.658807  0.321
2015 Summers BJ, Garcia BL, Woehl JL, Ramyar KX, Yao X, Geisbrecht BV. Identification of peptidic inhibitors of the alternative complement pathway based on Staphylococcus aureus SCIN proteins. Molecular Immunology. PMID 26052070 DOI: 10.1016/J.Molimm.2015.05.012  0.744
2015 Skaff DA, McWhorter WJ, Geisbrecht BV, Wyckoff GJ, Miziorko HM. Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds. Archives of Biochemistry and Biophysics. 566: 1-6. PMID 25499551 DOI: 10.1016/J.Abb.2014.12.002  0.736
2015 Stapels DA, Geisbrecht BV, Rooijakkers SH. Neutrophil serine proteases in antibacterial defense. Current Opinion in Microbiology. 23: 42-8. PMID 25461571 DOI: 10.1016/J.Mib.2014.11.002  0.396
2014 Woehl JL, Stapels DA, Garcia BL, Ramyar KX, Keightley A, Ruyken M, Syriga M, Sfyroera G, Weber AB, Zolkiewski M, Ricklin D, Lambris JD, Rooijakkers SH, Geisbrecht BV. The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase. Journal of Immunology (Baltimore, Md. : 1950). 193: 6161-71. PMID 25381436 DOI: 10.4049/Jimmunol.1401600  0.749
2014 Stapels DA, Ramyar KX, Bischoff M, von Köckritz-Blickwede M, Milder FJ, Ruyken M, Eisenbeis J, McWhorter WJ, Herrmann M, van Kessel KP, Geisbrecht BV, Rooijakkers SH. Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 111: 13187-92. PMID 25161283 DOI: 10.1073/Pnas.1407616111  0.466
2013 Choudhari SP, Kramer R, Barta ML, Greenwood JC, Geisbrecht BV, Joshi SB, Picking WD, Middaugh CR, Picking WL. Studies of the conformational stability of invasion plasmid antigen B from Shigella. Protein Science : a Publication of the Protein Society. 22: 666-70. PMID 23494968 DOI: 10.1002/Pro.2249  0.709
2013 Garcia BL, Summers BJ, Ramyar KX, Tzekou A, Lin Z, Ricklin D, Lambris JD, Laity JH, Geisbrecht BV. A structurally dynamic N-terminal helix is a key functional determinant in staphylococcal complement inhibitor (SCIN) proteins. The Journal of Biological Chemistry. 288: 2870-81. PMID 23233676 DOI: 10.1074/Jbc.M112.426858  0.769
2012 Barta ML, McWhorter WJ, Miziorko HM, Geisbrecht BV. Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. Biochemistry. 51: 5611-21. PMID 22734632 DOI: 10.1021/Bi300591X  0.768
2012 Bannantine JP, Lingle CK, Stabel JR, Ramyar KX, Garcia BL, Raeber AJ, Schacher P, Kapur V, Geisbrecht BV. MAP1272c encodes an NlpC/P60 protein, an antigen detected in cattle with Johne's disease. Clinical and Vaccine Immunology : Cvi. 19: 1083-92. PMID 22593240 DOI: 10.1128/Cvi.00195-12  0.704
2012 Skaff DA, Ramyar KX, McWhorter WJ, Barta ML, Geisbrecht BV, Miziorko HM. Biochemical and structural basis for inhibition of Enterococcus faecalis hydroxymethylglutaryl-CoA synthase, mvaS, by hymeglusin. Biochemistry. 51: 4713-22. PMID 22510038 DOI: 10.1021/Bi300037K  0.753
2012 Adam PR, Patil MK, Dickenson NE, Choudhari S, Barta M, Geisbrecht BV, Picking WL, Picking WD. Binding affects the tertiary and quaternary structures of the Shigella translocator protein IpaB and its chaperone IpgC. Biochemistry. 51: 4062-71. PMID 22497344 DOI: 10.1021/Bi300243Z  0.783
2012 Barta ML, Guragain M, Adam P, Dickenson NE, Patil M, Geisbrecht BV, Picking WL, Picking WD. Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure. Proteins. 80: 935-45. PMID 22423359 DOI: 10.1002/Prot.23251  0.773
2012 Bouyain S, Geisbrecht BV. Host glycan recognition by a pore forming toxin. Structure (London, England : 1993). 20: 197-8. PMID 22325766 DOI: 10.1016/J.Str.2012.01.013  0.397
2012 Barta ML, Dickenson NE, Patil M, Keightley A, Wyckoff GJ, Picking WD, Picking WL, Geisbrecht BV. The structures of coiled-coil domains from type III secretion system translocators reveal homology to pore-forming toxins. Journal of Molecular Biology. 417: 395-405. PMID 22321794 DOI: 10.1016/J.Jmb.2012.01.026  0.796
2012 Garcia BL, Summers BJ, Lin Z, Ramyar KX, Ricklin D, Kamath DV, Fu ZQ, Lambris JD, Geisbrecht BV. Diversity in the C3b [corrected] contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family. The Journal of Biological Chemistry. 287: 628-40. PMID 22086928 DOI: 10.1074/Jbc.M111.298984  0.761
2012 Garcia BL, Ramyar KX, Ricklin D, Lambris JD, Geisbrecht BV. Advances in understanding the structure, function, and mechanism of the SCIN and Efb families of Staphylococcal immune evasion proteins. Advances in Experimental Medicine and Biology. 946: 113-33. PMID 21948365 DOI: 10.1007/978-1-4614-0106-3_7  0.725
2012 Garcia BL, Summers BJ, Lin Z, Ramyar KX, Ricklin D, Kamath DV, Fu ZQ, Lambris JD, Geisbrecht BV. Diversity in the C3b contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family (Journal of Biological Chemistry (2012) 287, (628-640)) Journal of Biological Chemistry. 287: 9329. DOI: 10.1074/jbc.A111.298984  0.688
2012 Stapels DA, Ramyar KX, Ricklin D, Milder FJ, Bischoff M, Herrmann M, Geisbrecht BV, Lambris JD, von Köckritz-Blickwede M, Kessel KPv, Rooijakkers SH. Extracellular adherence protein (Eap) of Staphylococcus aureus evades innate immunity by inhibiting complement activation and neutrophil elastase Immunobiology. 217: 1170. DOI: 10.1016/J.Imbio.2012.08.118  0.431
2011 Barta ML, Skaff DA, McWhorter WJ, Herdendorf TJ, Miziorko HM, Geisbrecht BV. Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. The Journal of Biological Chemistry. 286: 23900-10. PMID 21561869 DOI: 10.1074/Jbc.M111.242016  0.77
2010 Chen H, Ricklin D, Hammel M, Garcia BL, McWhorter WJ, Sfyroera G, Wu YQ, Tzekou A, Li S, Geisbrecht BV, Woods VL, Lambris JD. Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proceedings of the National Academy of Sciences of the United States of America. 107: 17621-6. PMID 20876141 DOI: 10.1073/Pnas.1003750107  0.772
2010 Garcia BL, Ramyar KX, Tzekou A, Ricklin D, McWhorter WJ, Lambris JD, Geisbrecht BV. Molecular basis for complement recognition and inhibition determined by crystallographic studies of the staphylococcal complement inhibitor (SCIN) bound to C3c and C3b. Journal of Molecular Biology. 402: 17-29. PMID 20654625 DOI: 10.1016/J.Jmb.2010.07.029  0.76
2010 Barta ML, Zhang L, Picking WL, Geisbrecht BV. Evidence for alternative quaternary structure in a bacterial Type III secretion system chaperone. Bmc Structural Biology. 10: 21. PMID 20633281 DOI: 10.1186/1472-6807-10-21  0.773
2010 Bannantine JP, Stabel JR, Bayles DO, Geisbrecht BV. Characteristics of an extensive Mycobacterium avium subspecies paratuberculosis recombinant protein set. Protein Expression and Purification. 72: 223-33. PMID 20359537 DOI: 10.1016/J.Pep.2010.03.019  0.367
2010 Jongerius I, Garcia BL, Geisbrecht BV, van Strijp JA, Rooijakkers SH. Convertase inhibitory properties of Staphylococcal extracellular complement-binding protein. The Journal of Biological Chemistry. 285: 14973-9. PMID 20304920 DOI: 10.1074/Jbc.M109.091975  0.735
2010 Haspel N, Geisbrecht BV, Lambris J, Kavraki L. Multi-scale characterization of the energy landscape of proteins with application to the C3D/Efb-C complex. Proteins. 78: 1004-14. PMID 19899169 DOI: 10.1002/Prot.22624  0.435
2010 Garcia BL, Tzekou A, Ricklin D, Ramyar KX, McWhorter WJ, Geisbrecht BV, Lambris JD. Molecular basis for complement recognition and inhibition by staphylococcal complement inhibitors Molecular Immunology. 47: 2245-2245. DOI: 10.1016/J.Molimm.2010.05.145  0.684
2010 Ricklin D, Chen H, Hammel M, Garcia BL, McWhorter WJ, Sfyroera G, Wu Y, Tzekou A, Li S, Geisbrecht BV. Allosteric inhibition of complement function by the Staphylococcal immune evasion protein Efb Molecular Immunology. 47: 2244-2245. DOI: 10.1016/J.Molimm.2010.05.144  0.719
2009 Ricklin D, Tzekou A, Garcia BL, Hammel M, McWhorter WJ, Sfyroera G, Wu YQ, Holers VM, Herbert AP, Barlow PN, Geisbrecht BV, Lambris JD. A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family. Journal of Immunology (Baltimore, Md. : 1950). 183: 2565-74. PMID 19625656 DOI: 10.4049/Jimmunol.0901443  0.752
2009 Garcia BL, Tzekou A, Ramyar KX, McWhorter WJ, Ricklin D, Lambris JD, Geisbrecht BV. Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN). Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 482-5. PMID 19407382 DOI: 10.1107/S174430910901207X  0.725
2008 Geisbrecht BV. Staphylococcal complement inhibitors: biological functions, recognition of complement components, and potential therapeutic implications. Advances in Experimental Medicine and Biology. 632: 221-36. PMID 19025125 DOI: 10.1007/978-0-387-78952-1_16  0.476
2008 Ricklin D, Ricklin-Lichtsteiner SK, Markiewski MM, Geisbrecht BV, Lambris JD. Cutting edge: members of the Staphylococcus aureus extracellular fibrinogen-binding protein family inhibit the interaction of C3d with complement receptor 2. Journal of Immunology (Baltimore, Md. : 1950). 181: 7463-7. PMID 19017934 DOI: 10.4049/Jimmunol.181.11.7463  0.488
2008 Haspel N, Ricklin D, Geisbrecht BV, Kavraki LE, Lambris JD. Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Science : a Publication of the Protein Society. 17: 1894-906. PMID 18687868 DOI: 10.1110/Ps.036624.108  0.372
2008 Chen H, Schuster MC, Sfyroera G, Geisbrecht BV, Lambris JD. Solution insights into the structure of the Efb/C3 complement inhibitory complex as revealed by lysine acetylation and mass spectrometry. Journal of the American Society For Mass Spectrometry. 19: 55-65. PMID 18293486 DOI: 10.1016/J.Jasms.2007.10.009  0.517
2008 Lambris JD, Ricklin D, Geisbrecht BV. Complement evasion by human pathogens. Nature Reviews. Microbiology. 6: 132-42. PMID 18197169 DOI: 10.1038/Nrmicro1824  0.342
2008 Ricklin D, Ricklin-Lichtsteiner SK, Sfyroera G, Chen H, Tzekou A, Magotti P, Wu Y, Garcia BL, McWorther WJ, Haspel N, Kavraki LE, Geisbrecht BV, Lambris JD. Novel insights into target specificities and molecular mechanisms for two potent complement evasion proteins from Staphylococcus aureus Molecular Immunology. 45: 4114-4115. DOI: 10.1016/J.Molimm.2008.08.058  0.708
2007 Zemla A, Geisbrecht B, Smith J, Lam M, Kirkpatrick B, Wagner M, Slezak T, Zhou CE. STRALCP--structure alignment-based clustering of proteins. Nucleic Acids Research. 35: e150. PMID 18039711 DOI: 10.1093/Nar/Gkm1049  0.398
2007 Hammel M, Nemecek D, Keightley JA, Thomas GJ, Geisbrecht BV. The Staphylococcus aureus extracellular adherence protein (Eap) adopts an elongated but structured conformation in solution. Protein Science : a Publication of the Protein Society. 16: 2605-17. PMID 18029416 DOI: 10.1110/Ps.073170807  0.425
2007 Hammel M, Sfyroera G, Pyrpassopoulos S, Ricklin D, Ramyar KX, Pop M, Jin Z, Lambris JD, Geisbrecht BV. Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus. The Journal of Biological Chemistry. 282: 30051-61. PMID 17699522 DOI: 10.1074/Jbc.M704247200  0.469
2007 Hammel M, Sfyroera G, Ricklin D, Magotti P, Lambris JD, Geisbrecht BV. A structural basis for complement inhibition by Staphylococcus aureus. Nature Immunology. 8: 430-7. PMID 17351618 DOI: 10.1038/Ni1450  0.501
2007 Wang Z, Potter BM, Gray AM, Sacksteder KA, Geisbrecht BV, Laity JH. The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a new family of beta-grasp proteins. Journal of Molecular Biology. 366: 375-81. PMID 17174329 DOI: 10.1016/J.Jmb.2006.11.039  0.448
2007 Lambris JD, Sfyoera G, Hammel M, Ricklin D, Magotti P, Geisbrecht BV. A novel complement evasion mechanism of Staphylococcus aureus using Efb Molecular Immunology. 44: 3926. DOI: 10.1016/J.Molimm.2007.06.045  0.311
2006 McLellan JS, Yao S, Zheng X, Geisbrecht BV, Ghirlando R, Beachy PA, Leahy DJ. Structure of a heparin-dependent complex of Hedgehog and Ihog. Proceedings of the National Academy of Sciences of the United States of America. 103: 17208-13. PMID 17077139 DOI: 10.1073/Pnas.0606738103  0.325
2006 Xie C, Alcaide P, Geisbrecht BV, Schneider D, Herrmann M, Preissner KT, Luscinskas FW, Chavakis T. Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus. The Journal of Experimental Medicine. 203: 985-94. PMID 16585266 DOI: 10.1084/Jem.20051681  0.305
2006 Hammel M, Ramyar KX, Spencer CT, Geisbrecht BV. Crystallization and X-ray diffraction analysis of the complement component-3 (C3) inhibitory domain of Efb from Staphylococcus aureus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 285-8. PMID 16511324 DOI: 10.1107/S1744309106005926  0.392
2006 Geisbrecht BV, Bouyain S, Pop M. An optimized system for expression and purification of secreted bacterial proteins. Protein Expression and Purification. 46: 23-32. PMID 16260150 DOI: 10.1016/J.Pep.2005.09.003  0.43
2006 Geisbrecht BV, Nikonenko B, Samala R, Nakamura R, Nacy CA, Sacksteder KA. Design and optimization of a recombinant system for large-scale production of the MPT64 antigen from Mycobacterium tuberculosis. Protein Expression and Purification. 46: 64-72. PMID 16216527 DOI: 10.1016/J.Pep.2005.08.011  0.309
2005 Danahy JM, Potter BM, Geisbrecht BV, Laity JH. NMR assignment of protein Rv1980c from Mycobacterium tuberculosis. Journal of Biomolecular Nmr. 33: 73. PMID 16222561 DOI: 10.1007/S10858-005-1202-9  0.312
2005 Geisbrecht BV, Hamaoka BY, Perman B, Zemla A, Leahy DJ. The crystal structures of EAP domains from Staphylococcus aureus reveal an unexpected homology to bacterial superantigens. The Journal of Biological Chemistry. 280: 17243-50. PMID 15691839 DOI: 10.1074/Jbc.M412311200  0.422
2003 Geisbrecht BV, Dowd KA, Barfield RW, Longo PA, Leahy DJ. Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin. The Journal of Biological Chemistry. 278: 32561-8. PMID 12810718 DOI: 10.1074/Jbc.M302943200  0.397
2003 Gatto GJ, Maynard EL, Guerrerio AL, Geisbrecht BV, Gould SJ, Berg JM. Correlating structure and affinity for PEX5:PTS1 complexes. Biochemistry. 42: 1660-6. PMID 12578380 DOI: 10.1021/Bi027034Z  0.303
2000 Gatto GJ, Geisbrecht BV, Gould SJ, Berg JM. Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5. Nature Structural Biology. 7: 1091-5. PMID 11101887 DOI: 10.1038/81930  0.416
2000 Gatto GJ, Geisbrecht BV, Gould SJ, Berg JM. A proposed model for the PEX5-peroxisomal targeting signal-1 recognition complex. Proteins. 38: 241-6. PMID 10713985 DOI: 10.1002/(Sici)1097-0134(20000215)38:3<241::Aid-Prot1>3.0.Co;2-1  0.391
1999 Geisbrecht BV, Gould SJ. The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase. The Journal of Biological Chemistry. 274: 30527-33. PMID 10521434 DOI: 10.1074/Jbc.274.43.30527  0.368
1999 Geisbrecht BV, Liang X, Morrell JC, Schulz H, Gould SJ. The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase. The Journal of Biological Chemistry. 274: 25814-20. PMID 10464321 DOI: 10.1074/Jbc.274.36.25814  0.406
1999 Geisbrecht BV, Zhang D, Schulz H, Gould SJ. Characterization of PECI, a novel monofunctional Delta(3), Delta(2)-enoyl-CoA isomerase of mammalian peroxisomes. The Journal of Biological Chemistry. 274: 21797-803. PMID 10419495 DOI: 10.1074/Jbc.274.31.21797  0.36
1999 Geisbrecht BV, Schulz K, Nau K, Geraghty MT, Schulz H, Erdmann R, Gould SJ. Preliminary characterization of Yor180Cp: identification of a novel peroxisomal protein of saccharomyces cerevisiae involved in fatty acid metabolism. Biochemical and Biophysical Research Communications. 260: 28-34. PMID 10381339 DOI: 10.1006/Bbrc.1999.0860  0.311
1998 Geisbrecht BV, Zhu D, Schulz K, Nau K, Morrell JC, Geraghty M, Schulz H, Erdmann R, Gould SJ. Molecular characterization of Saccharomyces cerevisiae Delta3, Delta2-enoyl-CoA isomerase. The Journal of Biological Chemistry. 273: 33184-91. PMID 9837886 DOI: 10.1074/Jbc.273.50.33184  0.339
Show low-probability matches.