Steven L. Reiner - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Immunology, Human Development

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Barnett BE, Staupe RP, Odorizzi PM, Palko O, Tomov VT, Mahan AE, Gunn B, Chen D, Paley MA, Alter G, Reiner SL, Lauer GM, Teijaro JR, Wherry EJ. Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 27430722 DOI: 10.4049/Jimmunol.1500368  0.48
2016 Lau CM, Nish SA, Yogev N, Waisman A, Reiner SL, Reizis B. Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses. The Journal of Experimental Medicine. PMID 26903243 DOI: 10.1084/Jem.20150642  0.96
2016 Pikovskaya O, Chaix J, Rothman NJ, Collins A, Chen YH, Scipioni AM, Vivier E, Reiner SL. Cutting Edge: Eomesodermin Is Sufficient To Direct Type 1 Innate Lymphocyte Development into the Conventional NK Lineage. Journal of Immunology (Baltimore, Md. : 1950). PMID 26792802 DOI: 10.4049/Jimmunol.1502396  0.96
2015 Lin WW, Adams WC, Nish SA, Chen YH, Yen B, Rothman NJ, Kratchmarov R, Okada T, Klein U, Reiner SL. Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation. Cell Reports. PMID 26628372 DOI: 10.1016/J.Celrep.2015.10.072  0.96
2015 Reiner SL. T-bet transcendent: unmasking the faces of multifarious immunity. Journal of Immunology (Baltimore, Md. : 1950). 194: 2959-60. PMID 25795786 DOI: 10.4049/Jimmunol.1500289  0.96
2015 Harms Pritchard G, Hall AO, Christian DA, Wagage S, Fang Q, Muallem G, John B, Glatman Zaretsky A, Dunn WG, Perrigoue J, Reiner SL, Hunter CA. Diverse roles for T-bet in the effector responses required for resistance to infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 1131-40. PMID 25556247 DOI: 10.4049/Jimmunol.1401617  0.96
2014 Reiner SL, Adams WC. Lymphocyte fate specification as a deterministic but highly plastic process. Nature Reviews. Immunology. 14: 699-704. PMID 25190286 DOI: 10.1038/Nri3734  0.96
2014 Chaix J, Nish SA, Lin WH, Rothman NJ, Ding L, Wherry EJ, Reiner SL. Cutting edge: CXCR4 is critical for CD8+ memory T cell homeostatic self-renewal but not rechallenge self-renewal. Journal of Immunology (Baltimore, Md. : 1950). 193: 1013-6. PMID 24973450 DOI: 10.4049/Jimmunol.1400488  0.96
2013 Curran MA, Geiger TL, Montalvo W, Kim M, Reiner SL, Al-Shamkhani A, Sun JC, Allison JP. Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin. The Journal of Experimental Medicine. 210: 743-55. PMID 23547098 DOI: 10.1084/Jem.20121190  0.96
2013 Hodge RD, Garcia AJ, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF. Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4165-80. PMID 23447624 DOI: 10.1523/Jneurosci.4185-12.2013  0.96
2013 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF. The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proceedings of the National Academy of Sciences of the United States of America. 110: 4081-6. PMID 23431145 DOI: 10.1073/Pnas.1209076110  0.96
2013 Paley MA, Gordon SM, Bikoff EK, Robertson EJ, Wherry EJ, Reiner SL. Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes. Journal of Leukocyte Biology. 93: 307-15. PMID 23192430 DOI: 10.1189/jlb.0812400  0.96
2012 Paley MA, Kroy DC, Odorizzi PM, Johnnidis JB, Dolfi DV, Barnett BE, Bikoff EK, Robertson EJ, Lauer GM, Reiner SL, Wherry EJ. Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection. Science (New York, N.Y.). 338: 1220-5. PMID 23197535 DOI: 10.1126/Science.1229620  0.96
2012 Hall AO, Beiting DP, Tato C, John B, Oldenhove G, Lombana CG, Pritchard GH, Silver JS, Bouladoux N, Stumhofer JS, Harris TH, Grainger J, Wojno ED, Wagage S, Roos DS, ... ... Reiner SL, et al. The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity. 37: 511-23. PMID 22981537 DOI: 10.1016/j.immuni.2012.06.014  0.96
2012 Wang NS, McHeyzer-Williams LJ, Okitsu SL, Burris TP, Reiner SL, McHeyzer-Williams MG. Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα. Nature Immunology. 13: 604-11. PMID 22561605 DOI: 10.1038/Ni.2294  0.96
2012 Hodge RD, Nelson BR, Kahoud RJ, Yang R, Mussar KE, Reiner SL, Hevner RF. Tbr2 is essential for hippocampal lineage progression from neural stem cells to intermediate progenitors and neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6275-87. PMID 22553033 DOI: 10.1523/Jneurosci.0532-12.2012  0.96
2012 Ciocca ML, Barnett BE, Burkhardt JK, Chang JT, Reiner SL. Cutting edge: Asymmetric memory T cell division in response to rechallenge. Journal of Immunology (Baltimore, Md. : 1950). 188: 4145-8. PMID 22467651 DOI: 10.4049/Jimmunol.1200176  0.96
2012 Gordon SM, Chaix J, Rupp LJ, Wu J, Madera S, Sun JC, Lindsten T, Reiner SL. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity. 36: 55-67. PMID 22261438 DOI: 10.1016/J.Immuni.2011.11.016  0.96
2012 Barnett BE, Ciocca ML, Goenka R, Barnett LG, Wu J, Laufer TM, Burkhardt JK, Cancro MP, Reiner SL. Asymmetric B cell division in the germinal center reaction. Science (New York, N.Y.). 335: 342-4. PMID 22174128 DOI: 10.1126/Science.1213495  0.96
2011 Qui HZ, Hagymasi AT, Bandyopadhyay S, St Rose MC, Ramanarasimhaiah R, Ménoret A, Mittler RS, Gordon SM, Reiner SL, Vella AT, Adler AJ. CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 3555-64. PMID 21880986 DOI: 10.4049/Jimmunol.1101244  0.96
2011 Kao C, Oestreich KJ, Paley MA, Crawford A, Angelosanto JM, Ali MA, Intlekofer AM, Boss JM, Reiner SL, Weinmann AS, Wherry EJ. Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection. Nature Immunology. 12: 663-71. PMID 21623380 DOI: 10.1038/Ni.2046  0.96
2011 Chang JT, Ciocca ML, Kinjyo I, Palanivel VR, McClurkin CE, Dejong CS, Mooney EC, Kim JS, Steinel NC, Oliaro J, Yin CC, Florea BI, Overkleeft HS, Berg LJ, Russell SM, ... ... Reiner SL, et al. Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity. 34: 492-504. PMID 21497118 DOI: 10.1016/J.Immuni.2011.03.017  0.48
2011 Gordon SM, Carty SA, Kim JS, Zou T, Smith-Garvin J, Alonzo ES, Haimm E, Sant'Angelo DB, Koretzky GA, Reiner SL, Jordan MS. Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 4573-8. PMID 21383242 DOI: 10.4049/Jimmunol.1100037  0.96
2010 Kinjyo I, Gordon SM, Intlekofer AM, Dowdell K, Mooney EC, Caricchio R, Grupp SA, Teachey DT, Rao VK, Lindsten T, Reiner SL. Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin. Journal of Immunology (Baltimore, Md. : 1950). 185: 7151-5. PMID 21076068 DOI: 10.4049/Jimmunol.1003193  0.96
2010 Banerjee A, Gordon SM, Intlekofer AM, Paley MA, Mooney EC, Lindsten T, Wherry EJ, Reiner SL. Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche. Journal of Immunology (Baltimore, Md. : 1950). 185: 4988-92. PMID 20935204 DOI: 10.4049/Jimmunol.1002042  0.96
2010 Oliaro J, Van Ham V, Sacirbegovic F, Pasam A, Bomzon Z, Pham K, Ludford-Menting MJ, Waterhouse NJ, Bots M, Hawkins ED, Watt SV, Cluse LA, Clarke CJ, Izon DJ, Chang JT, ... ... Reiner SL, et al. Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 185: 367-75. PMID 20530266 DOI: 10.4049/Jimmunol.0903627  0.96
2010 Banerjee A, Schambach F, DeJong CS, Hammond SM, Reiner SL. Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells. European Journal of Immunology. 40: 225-31. PMID 19877012 DOI: 10.1002/Eji.200939381  0.96
2009 Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, Xu Y, Roots CM, Beilke JN, Banerjee A, Reiner SL, Miller SA, Weinmann AS, Goodnow CC, Lanier LL, et al. T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. The Journal of Experimental Medicine. 206: 2469-81. PMID 19808259 DOI: 10.1084/Jem.20090525  0.96
2009 Ahmed R, Bevan MJ, Reiner SL, Fearon DT. The precursors of memory: models and controversies. Nature Reviews. Immunology. 9: 662-8. PMID 19680250 DOI: 10.1038/Nri2619  0.96
2009 Shin H, Blackburn SD, Intlekofer AM, Kao C, Angelosanto JM, Reiner SL, Wherry EJ. A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection. Immunity. 31: 309-20. PMID 19664943 DOI: 10.1016/J.Immuni.2009.06.019  0.96
2009 Weinreich MA, Takada K, Skon C, Reiner SL, Jameson SC, Hogquist KA. KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. Immunity. 31: 122-30. PMID 19592277 DOI: 10.1016/J.Immuni.2009.05.011  0.96
2009 Kambayashi T, Allenspach EJ, Chang JT, Zou T, Shoag JE, Reiner SL, Caton AJ, Koretzky GA. Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 182: 4686-95. PMID 19342644 DOI: 10.4049/Jimmunol.0803180  0.96
2009 Hegel JK, Knieke K, Kolar P, Reiner SL, Brunner-Weinzierl MC. CD152 (CTLA-4) regulates effector functions of CD8+ T lymphocytes by repressing Eomesodermin. European Journal of Immunology. 39: 883-93. PMID 19224637 DOI: 10.1002/Eji.200838770  0.96
2009 Reiner SL. Decision making during the conception and career of CD4+ T cells. Nature Reviews. Immunology. 9: 81-2. PMID 19172726 DOI: 10.1038/Nri2490  0.96
2009 Debes GF, Reiner SL. Helping and harming have something in common. Nature Immunology. 10: 138-40. PMID 19148197 DOI: 10.1038/Ni0209-138  0.96
2008 Mrass P, Kinjyo I, Ng LG, Reiner SL, Puré E, Weninger W. CD44 mediates successful interstitial navigation by killer T cells and enables efficient antitumor immunity. Immunity. 29: 971-85. PMID 19100702 DOI: 10.1016/J.Immuni.2008.10.015  0.96
2008 Chang JT, Reiner SL. Asymmetric division and stem cell renewal without a permanent niche: Lessons from lymphocytes Cold Spring Harbor Symposia On Quantitative Biology. 73: 73-79. PMID 19022740 DOI: 10.1101/Sqb.2008.73.008  0.96
2008 Reiner SL. Inducing the T cell fates required for immunity. Immunologic Research. 42: 160-5. PMID 18806935 DOI: 10.1007/S12026-008-8054-9  0.96
2008 Intlekofer AM, Banerjee A, Takemoto N, Gordon SM, Dejong CS, Shin H, Hunter CA, Wherry EJ, Lindsten T, Reiner SL. Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science (New York, N.Y.). 321: 408-11. PMID 18635804 DOI: 10.1126/Science.1159806  0.96
2008 Chang JT, Reiner SL. Specifying helper T cell fates during immunity. Journal of Pediatric Gastroenterology and Nutrition. 46: E19-20. PMID 18354322 DOI: 10.1097/01.Mpg.0000313832.47207.0E  0.96
2008 Ng LG, Mrass P, Kinjyo I, Reiner SL, Weninger W. Two-photon imaging of effector T-cell behavior: lessons from a tumor model. Immunological Reviews. 221: 147-62. PMID 18275480 DOI: 10.1111/J.1600-065X.2008.00596.X  0.96
2007 Chang JT, Reiner SL. Protection one cell thick. Immunity. 27: 832-4. PMID 18093536 DOI: 10.1016/J.Immuni.2007.11.009  0.96
2007 Wei J, Duramad O, Perng OA, Reiner SL, Liu YJ, Qin FX. Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 18169-74. PMID 17978190 DOI: 10.1073/Pnas.0703642104  0.96
2007 Intlekofer AM, Takemoto N, Kao C, Banerjee A, Schambach F, Northrop JK, Shen H, Wherry EJ, Reiner SL. Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells. The Journal of Experimental Medicine. 204: 2015-21. PMID 17698591 DOI: 10.1084/Jem.20070841  0.96
2007 Schambach F, Schupp M, Lazar MA, Reiner SL. Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation. European Journal of Immunology. 37: 2396-9. PMID 17694576 DOI: 10.1002/Eji.200737621  0.96
2007 Reiner SL, Sallusto F, Lanzavecchia A. Division of labor with a workforce of one: challenges in specifying effector and memory T cell fate. Science (New York, N.Y.). 317: 622-5. PMID 17673652 DOI: 10.1126/Science.1143775  0.96
2007 Reiner SL. Development in motion: helper T cells at work. Cell. 129: 33-6. PMID 17418783 DOI: 10.1016/J.Cell.2007.03.019  0.96
2007 Chang JT, Palanivel VR, Kinjyo I, Schambach F, Intlekofer AM, Banerjee A, Longworth SA, Vinup KE, Mrass P, Oliaro J, Killeen N, Orange JS, Russell SM, Weninger W, Reiner SL. Asymmetric T lymphocyte division in the initiation of adaptive immune responses. Science (New York, N.Y.). 315: 1687-91. PMID 17332376 DOI: 10.1126/Science.1139393  0.96
2007 Chen L, He W, Kim ST, Tao J, Gao Y, Chi H, Intlekofer AM, Harvey B, Reiner SL, Yin Z, Flavell RA, Craft J. Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 2730-6. PMID 17312115 DOI: 10.4049/Jimmunol.178.5.2730  0.96
2007 Jenkinson SR, Intlekofer AM, Sun G, Feigenbaum L, Reiner SL, Bosselut R. Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. The Journal of Experimental Medicine. 204: 267-72. PMID 17296789 DOI: 10.1084/Jem.20061982  0.96
2006 Takemoto N, Intlekofer AM, Northrup JT, Wherry EJ, Reiner SL. Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 177: 7515-9. PMID 17114419 DOI: 10.4049/Jimmunol.177.11.7515  0.96
2006 Suto A, Wurster AL, Reiner SL, Grusby MJ. IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression. Journal of Immunology (Baltimore, Md. : 1950). 177: 3721-7. PMID 16951332 DOI: 10.4049/Jimmunol.177.6.3721  0.96
2006 Atherly LO, Lucas JA, Felices M, Yin CC, Reiner SL, Berg LJ. The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells. Immunity. 25: 79-91. PMID 16860759 DOI: 10.1016/J.Immuni.2006.05.012  0.96
2006 Intlekofer AM, Wherry EJ, Reiner SL. Not-so-great expectations: re-assessing the essence of T-cell memory. Immunological Reviews. 211: 203-13. PMID 16824129 DOI: 10.1111/J.0105-2896.2006.00396.X  0.96
2006 Gray PM, Reiner SL, Smith DF, Kaye PM, Scott P. Antigen-experienced T cells limit the priming of naive T cells during infection with Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 177: 925-33. PMID 16818747 DOI: 10.4049/Jimmunol.177.2.925  0.96
2006 Long M, Slaiby AM, Hagymasi AT, Mihalyo MA, Lichtler AC, Reiner SL, Adler AJ. T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression. Journal of Immunology (Baltimore, Md. : 1950). 176: 1036-45. PMID 16393991 DOI: 10.1182/Blood.V106.11.3321.3321  0.96
2006 Reiner SL. Can daughter cells be different during immune responses to parasites? Parasite Immunology. 28: 238-239. DOI: 10.1111/j.1365-3024.2006.00872.x  0.96
2005 Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, ... ... Reiner SL, et al. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nature Immunology. 6: 1236-44. PMID 16273099 DOI: 10.1038/Ni1268  0.96
2005 Martins GA, Hutchins AS, Reiner SL. Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expression. Journal of Immunology (Baltimore, Md. : 1950). 175: 5981-5. PMID 16237092 DOI: 10.4049/Jimmunol.175.9.5981  0.96
2005 Hutchins AS, Artis D, Hendrich BD, Bird AP, Scott P, Reiner SL. Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. Journal of Immunology (Baltimore, Md. : 1950). 175: 5606-10. PMID 16237047 DOI: 10.4049/Jimmunol.175.9.5606  0.96
2005 Reiner SL. Epigenetic control in the immune response. Human Molecular Genetics. 14: R41-6. PMID 15809272 DOI: 10.1093/Hmg/Ddi115  0.96
2005 Sallusto F, Reiner SL. Sliding doors in the immune response. Nature Immunology. 6: 10-2. PMID 15611774 DOI: 10.1038/Ni0105-10  0.96
2004 Hewitt SL, High FA, Reiner SL, Fisher AG, Merkenschlager M. Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation. European Journal of Immunology. 34: 3604-13. PMID 15484194 DOI: 10.1002/Eji.200425469  0.96
2004 Anfossi N, Robbins SH, Ugolini S, Georgel P, Hoebe K, Bouneaud C, Ronet C, Kaser A, DiCioccio CB, Tomasello E, Blumberg RS, Beutler B, Reiner SL, Alexopoulou L, Lantz O, et al. Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules. Journal of Immunology (Baltimore, Md. : 1950). 173: 3773-82. PMID 15356124 DOI: 10.4049/Jimmunol.173.6.3773  0.96
2004 Tato CM, Martins GA, High FA, DiCioccio CB, Reiner SL, Hunter CA. Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. Journal of Immunology (Baltimore, Md. : 1950). 173: 1514-7. PMID 15265878 DOI: 10.4049/Jimmunol.173.3.1514  0.96
2004 Lieberman LA, Banica M, Reiner SL, Hunter CA. STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). 172: 457-63. PMID 14688355 DOI: 10.4049/Jimmunol.172.1.457  0.96
2003 Reiner SL. Immunity and the animation of the genome. Immunity. 19: 775-80. PMID 14670295 DOI: 10.1016/S1074-7613(03)00333-9  0.96
2003 Pearce EL, Mullen AC, Martins GA, Krawczyk CM, Hutchins AS, Zediak VP, Banica M, DiCioccio CB, Gross DA, Mao CA, Shen H, Cereb N, Yang SY, Lindsten T, Rossant J, ... ... Reiner SL, et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (New York, N.Y.). 302: 1041-3. PMID 14605368 DOI: 10.1126/Science.1090148  0.96
2003 Reiner SL, Mullen AC, Hutchins AS, Pearce EL. Helper T cell differentiation and the problem of cellular inheritance. Immunologic Research. 27: 463-8. PMID 12857989 DOI: 10.1385/Ir:27:2-3:463  0.96
2002 Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nature Reviews. Immunology. 2: 933-44. PMID 12461566 DOI: 10.1038/Nri954  0.96
2002 Hutchins AS, Mullen AC, Lee HW, Sykes KJ, High FA, Hendrich BD, Bird AP, Reiner SL. Gene silencing quantitatively controls the function of a developmental trans-activator. Molecular Cell. 10: 81-91. PMID 12150909 DOI: 10.1016/S1097-2765(02)00564-6  0.96
2002 Mullen AC, Hutchins AS, High FA, Lee HW, Sykes KJ, Chodosh LA, Reiner SL. Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nature Immunology. 3: 652-8. PMID 12055627 DOI: 10.1038/Ni807  0.96
2001 Mullen AC, Hutchins AS, Villarino AV, Lee HW, High FA, Cereb N, Yang SY, Hua X, Reiner SL. Cell cycle controlling the silencing and functioning of mammalian activators. Current Biology : Cb. 11: 1695-9. PMID 11696328 DOI: 10.1016/S0960-9822(01)00533-4  0.96
2001 Doyle AM, Mullen AC, Villarino AV, Hutchins AS, High FA, Lee HW, Thompson CB, Reiner SL. Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells. The Journal of Experimental Medicine. 194: 893-902. PMID 11581312 DOI: 10.1084/Jem.194.7.893  0.96
2001 Reiner SL. Helper T cell differentiation, inside and out Current Opinion in Immunology. 13: 351-355. PMID 11406368 DOI: 10.1016/S0952-7915(00)00226-0  0.96
2001 Mullen AC, High FA, Hutchins AS, Lee HW, Villarino AV, Livingston DM, Kung AL, Cereb N, Yao TP, Yang SY, Reiner SL. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science (New York, N.Y.). 292: 1907-10. PMID 11397944 DOI: 10.1126/Science.1059835  0.96
2000 Brown CR, Reiner SL. Genes outside the major histocompatibility complex control resistance and susceptibility to experimental Lyme arthritis. Medical Microbiology and Immunology. 189: 85-90. PMID 11138641 DOI: 10.1007/S004300000044  0.96
2000 Brown CR, Reiner SL. Bone-marrow chimeras reveal hemopoietic and nonhemopoietic control of resistance to experimental Lyme arthritis. Journal of Immunology (Baltimore, Md. : 1950). 165: 1446-52. PMID 10903749 DOI: 10.4049/Jimmunol.165.3.1446  0.96
2000 Hunter CA, Reiner SL. Cytokines and T cells in host defense Current Opinion in Immunology. 12: 413-418. PMID 10899023 DOI: 10.1016/S0952-7915(00)00110-2  0.96
2000 Masteller EL, Chuang E, Mullen AC, Reiner SL, Thompson CB. Structural analysis of CTLA-4 function in vivo. Journal of Immunology (Baltimore, Md. : 1950). 164: 5319-27. PMID 10799894 DOI: 10.4049/Jimmunol.164.10.5319  0.96
2000 Finkelman FD, Morris SC, Orekhova T, Mori M, Donaldson D, Reiner SL, Reilly NL, Schopf L, Urban JF. Stat6 regulation of in vivo IL-4 responses Journal of Immunology. 164: 2303-2310. PMID 10679064 DOI: 10.4049/Jimmunol.164.5.2303  0.96
1999 Pippig SD, Peña-Rossi C, Long J, Godfrey WR, Fowell DJ, Reiner SL, Birkeland ML, Locksley RM, Barclay AN, Killeen N. Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). Journal of Immunology (Baltimore, Md. : 1950). 163: 6520-9. PMID 10586044  0.96
1999 Reiner SL, Seder RA. Dealing from the evolutionary pawnshop: How lymphocytes make decisions Immunity. 11: 1-10. PMID 10435574 DOI: 10.1016/S1074-7613(00)80076-X  0.96
1999 Coffman RL, Reiner SL. Instruction, selection, or tampering with the odds? Science. 284: 1283-1285. PMID 10383307 DOI: 10.1126/Science.284.5418.1283  0.96
1999 Brown CR, Reiner SL. Experimental lyme arthritis in the absence of interleukin-4 or gamma interferon. Infection and Immunity. 67: 3329-33. PMID 10377109 DOI: 10.1128/Iai.67.7.3329-3333.1999  0.96
1999 Brown CR, Reiner SL. Development of lyme arthritis in mice deficient in inducible nitric oxide synthase. The Journal of Infectious Diseases. 179: 1573-6. PMID 10228086 DOI: 10.1086/314774  0.96
1999 Brown CR, Reiner SL. Genetic control of experimental lyme arthritis in the absence of specific immunity. Infection and Immunity. 67: 1967-73. PMID 10085044 DOI: 10.1128/Iai.67.4.1967-1973.1999  0.96
1999 Brown DR, Reiner SL. Polarized helper-T-cell responses against Leishmania major in the absence of B cells Infection and Immunity. 67: 266-270. PMID 9864225 DOI: 10.1128/Iai.67.1.266-270.1999  0.96
1998 Brown CR, Reiner SL. Activation of natural killer cells in arthritis-susceptible but not arthritis-resistant mouse strains following Borrelia burgdorferi infection. Infection and Immunity. 66: 5208-14. PMID 9784524 DOI: 10.1128/Iai.66.11.5208-5214.1998  0.96
1998 Noel PJ, Alegre ML, Reiner SL, Thompson CB. Impaired negative selection in CD28-deficient mice Cellular Immunology. 187: 131-138. PMID 9732701 DOI: 10.1006/Cimm.1998.1332  0.96
1998 Bird JJ, Brown DR, Mullen AC, Moskowitz NH, Mahowald MA, Sider JR, Gajewski TF, Wang CR, Reiner SL. Helper T cell differentiation is controlled by the cell cycle. Immunity. 9: 229-37. PMID 9729043 DOI: 10.1016/S1074-7613(00)80605-6  0.96
1998 Brown CR, Reiner SL. Clearance of Borrelia burgdorferi may not be required for resistance to experimental lyme arthritis. Infection and Immunity. 66: 2065-71. PMID 9573090 DOI: 10.1128/Iai.66.5.2065-2071.1998  0.96
1998 Reiner SL, Fowell DJ, Moskowitz NH, Swier K, Brown DR, Brown CR, Turck CW, Scott PA, Killeen N, Locksley RM. Control of Leishmania major by a monoclonal alpha beta T cell repertoire. Journal of Immunology (Baltimore, Md. : 1950). 160: 884-9. PMID 9551925  0.96
1998 Swier K, Brown DR, Bird JJ, Martin WD, Van Kaer L, Reiner SL. A critical, invariant chain-independent role for H2-M in antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 160: 540-4. PMID 9551884  0.96
1998 Gilffillan MC, Noel PJ, Podack ER, Reiner SL, Thompson CB. Expression of the costimulatory receptor CD30 is regulated by both CD28 and cytokines Journal of Immunology. 160: 2180-2187. PMID 9498756  0.96
1998 Khoruts A, Mondino A, Pape KA, Reiner SL, Jenkins MK. A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism. The Journal of Experimental Medicine. 187: 225-36. PMID 9432980 DOI: 10.1084/Jem.187.2.225  0.96
1997 Gurunathan S, Sacks DL, Brown DR, Reiner SL, Charest H, Glaichenhaus N, Seder RA. Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major. The Journal of Experimental Medicine. 186: 1137-47. PMID 9314562 DOI: 10.1084/Jem.186.7.1137  0.96
1997 Brown DR, Moskowitz NH, Killeen N, Reiner SL. A role for CD4 in peripheral T cell differentiation Journal of Experimental Medicine. 186: 101-107. PMID 9207001 DOI: 10.1084/Jem.186.1.101  0.96
1997 Sato S, Reiner SL, Jensen MA, Roos RP. Central nervous system cytokine mRNA expression following Theiler's murine encephalomyelitis virus infection. Journal of Neuroimmunology. 76: 213-23. PMID 9184653 DOI: 10.1016/S0165-5728(97)00059-3  0.96
1997 Moskowitz NH, Brown DR, Reiner SL. Efficient immunity against Leishmania major in the absence of interleukin-6 Infection and Immunity. 65: 2448-2450. PMID 9169788  0.96
1997 Brown DR, Swier K, Moskowitz NH, Naujokas MF, Locksley RM, Reiner SL. T helper subset differentiation in the absence of invariant chain Journal of Experimental Medicine. 185: 31-41. PMID 8996239 DOI: 10.1084/Jem.185.1.31  0.96
1996 Brown DR, Green JM, Moskowitz NH, Davis M, Thompson CB, Reiner SL. Limited role of CD28-mediated signals in T helper subset differentiation Journal of Experimental Medicine. 184: 803-810. PMID 9064340 DOI: 10.1084/Jem.184.3.803  0.96
1996 Alegre ML, Noel PJ, Eisfelder BJ, Chuang E, Clark MR, Reiner SL, Thompson CB. Regulation of Surface and Intracellular Expression of CTLA4 on Mouse T Cells Journal of Immunology. 157: 4762-4770. PMID 8943377  0.96
1996 Brown DR, Fowell DJ, Corry DB, Wynn TA, Moskowitz NH, Cheever AW, Locksley RM, Reiner SL. β2-Microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses Journal of Experimental Medicine. 184: 1295-1304. PMID 8879201 DOI: 10.1084/Jem.184.4.1295  0.96
1996 Brown CR, Reiner SL. Prevention of experimental lyme arthritis by blocking nitric oxide induction with aminoguanidine Faseb Journal. 10.  0.96
1996 Brown DR, Kileen N, Reiner SL. Balb cd4-deficient mice default from th2 to th1 responses during murine leishmaniasis Faseb Journal. 10.  0.96
1996 Swier K, Brown D, Naujokas MF, Reiner SL. Invariant chain-knockout mice heal leishmania infection despite inefficient antigen presentation Faseb Journal. 10.  0.96
1995 Matyniak JE, Reiner SL. T helper phenotype and genetic susceptibility in experimental lyme disease Journal of Experimental Medicine. 181: 1251-1254. PMID 7869043 DOI: 10.1084/jem.181.3.1251  0.96
1995 Reiner SL, Locksley RM. The regulation of immunity to Leishmania major Annual Review of Immunology. 13: 151-177. PMID 7612219 DOI: 10.1146/Annurev.Iy.13.040195.001055  0.96
1995 Reiner SL, Seder RA. T helper cell differentiation in immune response Current Opinion in Immunology. 7: 360-366. PMID 7546401 DOI: 10.1016/0952-7915(95)80111-1  0.96
1995 Pearce EJ, Reiner SL. Induction of Th2 responses in infectious diseases Current Opinion in Immunology. 7: 497-504. PMID 7495513 DOI: 10.1016/0952-7915(95)80094-8  0.96
1994 Reiner SL, Zheng S, Corry DB, Locksley RM. Constructing polycompetitor cDNAs for quantitative PCR. J. Immunol. Methods 165 (1993) 37-46 (PII:0022-1759(93)90104-F) Journal of Immunological Methods. 173: 133. PMID 8034981 DOI: 10.1016/0022-1759(94)90291-7  0.96
1994 Reiner SL, Zheng S, Corry DB, Locksley RM. Constructing polycompetitor cDNAs for quantitative PCR. (J. Immunol. Methods 165 (1993) 37-46; 173 (1994) 133) (PII:0022-1759(94)00210-X) Journal of Immunological Methods. 175: 275. PMID 7930655 DOI: 10.1016/0022-1759(94)90370-0  0.96
1994 Wang ZE, Reiner SL, Zheng S, Dalton DK, Locksley RM. CD4+ effector cells default to the Th2 pathway in interferon γ-deficient mice infected with Leishmania major Journal of Experimental Medicine. 179: 1367-1371. PMID 7908325 DOI: 10.1084/Jem.179.4.1367  0.96
1994 Reiner SL, Zheng S, Wang ZE, Stowring L, Locksley RM. Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection Journal of Experimental Medicine. 179: 447-456. PMID 7905017 DOI: 10.1084/Jem.179.2.447  0.96
1994 Wang ZE, Zheng S, Corry DB, Dalton DK, Seder RA, Reiner SL, Locksley RM. Interferon γ-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major Proceedings of the National Academy of Sciences of the United States of America. 91: 12932-12936. PMID 7809149 DOI: 10.1073/Pnas.91.26.12932  0.96
1994 Corry DB, Reiner SL, Linsley PS, Locksley RM. Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental Leishmaniasis Journal of Immunology. 153: 4142-4148. PMID 7523517  0.96
1994 Reiner SL. Parasites and T helper cell development: Some insights Parasitology Today. 10: 485-488. DOI: 10.1016/0169-4758(94)90162-7  0.96
1993 Reiner SL, Wang ZE, Hatam F, Scott P, Locksley RM. TH1 and TH2 cell antigen receptors in experimental leishmaniasis Science. 259: 1457-1463. PMID 8451641 DOI: 10.1126/Science.8451641  0.96
1993 Reiner SL, Zheng S, Corry DB, Locksley RM. Constructing polycompetitor cDNAs for quantitative PCR Journal of Immunological Methods. 165: 37-46. PMID 8409467 DOI: 10.1016/0022-1759(93)90104-F  0.96
1993 Locksley RM, Reiner SL, Hatam F, Littman DR, Killeen N. Helper T cells without CD4: Control of leishmaniasis in CD4-deficient mice Science. 261: 1448-1451. PMID 8367726 DOI: 10.1126/Science.8367726  0.96
1993 Wang ZE, Reiner SL, Hatam F, Heinzel FP, Bouvier J, Turck CW, Locksley RM. Targeted activation of CD8 cells and infection of β2-microglobulin-deficient mice fail to confirm a primary protective role for CD8 cells in experimental Leishmaniasis Journal of Immunology. 151: 2077-2086. PMID 8102158  0.96
1993 Tobin JF, Reiner SL, Hatam F, Zheng S, Leptak CL, Wirth DF, Locksley RM. Transfected Leishmania expressing biologically active IFN-γ Journal of Immunology. 150: 5059-5069. PMID 8098724  0.96
1993 Reiner SL, Locksley RM. Cytokines in the differentiation of Th1/Th2 CD4+ subsets in leishmaniasis Journal of Cellular Biochemistry. 53: 323-328. PMID 7905485 DOI: 10.1002/Jcb.240530409  0.96
1993 Reiner SL, Locksley RM. The worm and the protozoa: Stereotyped responses or distinct antigens? Parasitology Today. 9: 258-260. DOI: 10.1016/0169-4758(93)90071-M  0.96
1992 Reiner SL, Locksley RM. Lessons from Leishmania: a model for investigations of CD4+ subset differentiation Infectious Agents and Disease. 1: 33-42. PMID 1365527  0.96
1991 Holaday BJ, Sadick MD, Wang ZE, Reiner SL, Heinzel FP, Parslow TG, Locksley RM. Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- and Th2-like cell lines Journal of Immunology. 147: 1653-1658. PMID 1831830  0.96
1991 Locksley RM, Heinzel FP, Holaday BJ, Mutha SS, Reiner SL, Sadick MD. Induction of Th1 and Th2 CD4+ subsets during murine Leishmania major infection Research in Immunology. 142: 28-32. PMID 1829257 DOI: 10.1016/0923-2494(91)90007-6  0.96
1987 Lallinger GJ, Reiner SL, Cooke DW, Toffaletti DL, Perfect JR, Granger DL, Durack DT. Efficacy of immune therapy in early experimental Naegleria fowleri meningitis. Infection and Immunity. 55: 1289-93. PMID 3570464  0.96
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