Shelley L. Berger - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Biochemistry, Genetics

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sen P, Lan Y, Li CY, Sidoli S, Donahue G, Dou Z, Frederick B, Chen Q, Luense LJ, Garcia BA, Dang W, Johnson FB, Adams PD, Schultz DC, Berger SL. Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence. Molecular Cell. PMID 30773298 DOI: 10.1016/j.molcel.2019.01.021  0.52
2016 Zhu J, Dou Z, Sammons MA, Levine AJ, Berger SL. Lysine methylation represses p53 activity in teratocarcinoma cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27535933 DOI: 10.1073/pnas.1610387113  0.52
2016 Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT, Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL, Nixon C, Clark W, ... ... Berger SL, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biology. 17: 158. PMID 27457071 DOI: 10.1186/s13059-016-1017-x  0.52
2016 Luense LJ, Wang X, Schon SB, Weller AH, Lin Shiao E, Bryant JM, Bartolomei MS, Coutifaris C, Garcia BA, Berger SL. Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells. Epigenetics & Chromatin. 9: 24. PMID 27330565 DOI: 10.1186/s13072-016-0072-6  0.52
2016 Capell BC, Drake AM, Zhu J, Shah PP, Dou Z, Dorsey J, Simola DF, Donahue G, Sammons M, Rai TS, Natale C, Ridky TW, Adams PD, Berger SL. MLL1 is essential for the senescence-associated secretory phenotype. Genes & Development. 30: 321-36. PMID 26833731 DOI: 10.1101/gad.271882.115  0.52
2016 Simola DF, Graham RJ, Brady CM, Enzmann BL, Desplan C, Ray A, Zwiebel LJ, Bonasio R, Reinberg D, Liebig J, Berger SL. Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus. Science (New York, N.Y.). 351. PMID 26722000 DOI: 10.1126/science.aac6633  0.52
2016 Mews P, Berger SL. Exploring the Dynamic Relationship Between Cellular Metabolism and Chromatin Structure Using SILAC-Mass Spec and ChIP-Sequencing Methods in Enzymology. DOI: 10.1016/bs.mie.2016.04.002  0.52
2015 Dou Z, Ivanov A, Adams PD, Berger SL. Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress. Autophagy. 0. PMID 26654219 DOI: 10.1080/15548627.2015.1127465  0.52
2015 Hu J, Donahue G, Dorsey J, Govin J, Yuan Z, Garcia BA, Shah PP, Berger SL. H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis. Cell Reports. PMID 26628362 DOI: 10.1016/j.celrep.2015.10.070  0.52
2015 Dou Z, Xu C, Donahue G, Shimi T, Pan JA, Zhu J, Ivanov A, Capell BC, Drake AM, Shah PP, Catanzaro JM, Daniel Ricketts M, Lamark T, Adam SA, Marmorstein R, ... ... Berger SL, et al. Autophagy mediates degradation of nuclear lamina. Nature. 527: 105-9. PMID 26524528 DOI: 10.1038/nature15548  0.52
2015 Zhu J, Sammons MA, Donahue G, Dou Z, Vedadi M, Getlik M, Barsyte-Lovejoy D, Al-awar R, Katona BW, Shilatifard A, Huang J, Hua X, Arrowsmith CH, Berger SL. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 525: 206-11. PMID 26331536 DOI: 10.1038/nature15251  0.52
2015 Sen P, Dang W, Donahue G, Dai J, Dorsey J, Cao X, Liu W, Cao K, Perry R, Lee JY, Wasko BM, Carr DT, He C, Robison B, Wagner J, ... ... Berger SL, et al. H3K36 methylation promotes longevity by enhancing transcriptional fidelity. Genes & Development. 29: 1362-1376. PMID 26159996 DOI: 10.1101/gad.263707.115  0.52
2015 Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL. Characterization of BRD4 during mammalian postmeiotic sperm development. Molecular and Cellular Biology. 35: 1433-48. PMID 25691659 DOI: 10.1128/MCB.01328-14  0.52
2015 Sammons MA, Zhu J, Drake AM, Berger SL. TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity. Genome Research. 25: 179-88. PMID 25391375 DOI: 10.1101/gr.181883.114  0.52
2015 Qin J, Rajaratnam R, Feng L, Salami J, Barber-Rotenberg JS, Domsic J, Reyes-Uribe P, Liu H, Dang W, Berger SL, Villanueva J, Meggers E, Marmorstein R. Development of organometallic S6K1 inhibitors. Journal of Medicinal Chemistry. 58: 305-14. PMID 25356520 DOI: 10.1021/jm5011868  0.52
2015 Yan H, Bonasio R, Simola DF, Liebig J, Berger SL, Reinberg D. DNA methylation in social insects: how epigenetics can control behavior and longevity. Annual Review of Entomology. 60: 435-52. PMID 25341091 DOI: 10.1146/annurev-ento-010814-020803  0.52
2014 Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. Geroscience: linking aging to chronic disease. Cell. 159: 709-13. PMID 25417146 DOI: 10.1016/j.cell.2014.10.039  0.52
2014 Mews P, Zee BM, Liu S, Donahue G, Garcia BA, Berger SL. Histone methylation has dynamics distinct from those of histone acetylation in cell cycle reentry from quiescence. Molecular and Cellular Biology. 34: 3968-80. PMID 25154414 DOI: 10.1128/MCB.00763-14  0.52
2014 McCormick MA, Mason AG, Guyenet SJ, Dang W, Garza RM, Ting MK, Moller RM, Berger SL, Kaeberlein M, Pillus L, La Spada AR, Kennedy BK. The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. Cell Reports. 8: 477-86. PMID 25043177 DOI: 10.1016/j.celrep.2014.06.037  0.52
2014 Lin S, Wein S, Gonzales-Cope M, Otte GL, Yuan ZF, Afjehi-Sadat L, Maile T, Berger SL, Rush J, Lill JR, Arnott D, Garcia BA. Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry. Molecular & Cellular Proteomics : McP. 13: 2450-66. PMID 25000943 DOI: 10.1074/mcp.O113.036459  0.52
2014 Brunet A, Berger SL. Epigenetics of aging and aging-related disease. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: S17-20. PMID 24833581 DOI: 10.1093/gerona/glu042  0.52
2014 Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, ... ... Berger SL, et al. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. Cell Metabolism. 19: 952-66. PMID 24814484 DOI: 10.1016/j.cmet.2014.04.004  0.52
2013 Cruickshanks HA, McBryan T, Nelson DM, Vanderkraats ND, Shah PP, van Tuyn J, Singh Rai T, Brock C, Donahue G, Dunican DS, Drotar ME, Meehan RR, Edwards JR, Berger SL, Adams PD. Senescent cells harbour features of the cancer epigenome. Nature Cell Biology. 15: 1495-506. PMID 24270890 DOI: 10.1038/ncb2879  0.52
2013 Bryant JM, Meyer-Ficca ML, Dang VM, Berger SL, Meyer RG. Separation of spermatogenic cell types using STA-PUT velocity sedimentation. Journal of Visualized Experiments : Jove. PMID 24145866 DOI: 10.3791/50648  0.52
2013 Shah PP, Donahue G, Otte GL, Capell BC, Nelson DM, Cao K, Aggarwala V, Cruickshanks HA, Rai TS, McBryan T, Gregory BD, Adams PD, Berger SL. Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape. Genes & Development. 27: 1787-99. PMID 23934658 DOI: 10.1101/gad.223834.113  0.52
2013 Ivanov A, Pawlikowski J, Manoharan I, van Tuyn J, Nelson DM, Rai TS, Shah PP, Hewitt G, Korolchuk VI, Passos JF, Wu H, Berger SL, Adams PD. Lysosome-mediated processing of chromatin in senescence. The Journal of Cell Biology. 202: 129-43. PMID 23816621 DOI: 10.1083/jcb.201212110  0.52
2013 Capell BC, Berger SL. Genome-wide epigenetics. The Journal of Investigative Dermatology. 133: e9. PMID 23673507 DOI: 10.1038/jid.2013.173  0.52
2013 Simola DF, Wissler L, Donahue G, Waterhouse RM, Helmkampf M, Roux J, Nygaard S, Glastad KM, Hagen DE, Viljakainen L, Reese JT, Hunt BG, Graur D, Elhaik E, Kriventseva EV, ... ... Berger SL, et al. Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality. Genome Research. 23: 1235-47. PMID 23636946 DOI: 10.1101/gr.155408.113  0.52
2013 Simola DF, Ye C, Mutti NS, Dolezal K, Bonasio R, Liebig J, Reinberg D, Berger SL. A chromatin link to caste identity in the carpenter ant Camponotus floridanus. Genome Research. 23: 486-96. PMID 23212948 DOI: 10.1101/gr.148361.112  0.52
2012 Bryant JM, Berger SL. Low-hanging fruit: targeting Brdt in the testes. The Embo Journal. 31: 3788-9. PMID 22960636 DOI: 10.1038/emboj.2012.259  0.52
2012 Zhou X, Slone JD, Rokas A, Berger SL, Liebig J, Ray A, Reinberg D, Zwiebel LJ. Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding. Plos Genetics. 8: e1002930. PMID 22952454 DOI: 10.1371/journal.pgen.1002930  0.52
2012 Bonasio R, Li Q, Lian J, Mutti NS, Jin L, Zhao H, Zhang P, Wen P, Xiang H, Ding Y, Jin Z, Shen SS, Wang Z, Wang W, Wang J, ... Berger SL, et al. Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator. Current Biology : Cb. 22: 1755-64. PMID 22885060 DOI: 10.1016/j.cub.2012.07.042  0.52
2012 Bryant JM, Govin J, Zhang L, Donahue G, Pugh BF, Berger SL. The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae. Molecular and Cellular Biology. 32: 2771-83. PMID 22586276 DOI: 10.1128/MCB.00282-12  0.52
2012 Mallory MJ, Law MJ, Sterner DE, Berger SL, Strich R. Gcn5p-dependent acetylation induces degradation of the meiotic transcriptional repressor Ume6p. Molecular Biology of the Cell. 23: 1609-17. PMID 22438583 DOI: 10.1091/mbc.E11-06-0536  0.52
2012 Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature. 483: 474-8. PMID 22343901 DOI: 10.1038/nature10860  0.52
2012 Berger SL. Transgenerational inheritance of longevity: epigenetic mysteries abound. Cell Metabolism. 15: 6-7. PMID 22225870 DOI: 10.1016/j.cmet.2011.12.012  0.52
2012 Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, ... ... Berger SL, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. The Embo Journal. 31: 58-70. PMID 22020126 DOI: 10.1038/emboj.2011.382  0.52
2011 Edwards CR, Dang W, Berger SL. Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing. Biochemistry. 50: 10473-83. PMID 21985125 DOI: 10.1021/bi201120q  0.52
2011 Lu JY, Lin YY, Sheu JC, Wu JT, Lee FJ, Chen Y, Lin MI, Chiang FT, Tai TY, Berger SL, Zhao Y, Tsai KS, Zhu H, Chuang LM, Boeke JD. Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell. 146: 969-79. PMID 21906795 DOI: 10.1016/j.cell.2011.07.044  0.52
2011 Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J, Huang P, Sawyer SK, Fuerth B, Faubert B, Kalliomäki T, Elia A, Luo X, Nadeem V, Bungard D, ... ... Berger SL, et al. Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes & Development. 25: 1041-51. PMID 21576264 DOI: 10.1101/gad.1987211  0.52
2011 Zediak VP, Wherry EJ, Berger SL. The contribution of epigenetic memory to immunologic memory. Current Opinion in Genetics & Development. 21: 154-9. PMID 21330128 DOI: 10.1016/j.gde.2011.01.016  0.52
2011 Trujillo KM, Tyler RK, Ye C, Berger SL, Osley MA. A genetic and molecular toolbox for analyzing histone ubiquitylation and sumoylation in yeast Methods. 54: 296-303. PMID 21310241 DOI: 10.1016/j.ymeth.2011.02.003  0.52
2011 Zediak VP, Johnnidis JB, Wherry EJ, Berger SL. Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status. Journal of Immunology (Baltimore, Md. : 1950). 186: 2705-9. PMID 21278341 DOI: 10.4049/jimmunol.1003741  0.52
2010 Berger SL. Cell signaling and transcriptional regulation via histone phosphorylation Cold Spring Harbor Symposia On Quantitative Biology. 75: 23-26. PMID 21467136 DOI: 10.1101/sqb.2010.75.044  0.52
2010 Yu Y, Zeng P, Xiong J, Liu Z, Berger SL, Merlino G. Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene. Plos One. 5: e12710. PMID 20856924 DOI: 10.1371/journal.pone.0012710  0.52
2010 Bonasio R, Zhang G, Ye C, Mutti NS, Fang X, Qin N, Donahue G, Yang P, Li Q, Li C, Zhang P, Huang Z, Berger SL, Reinberg D, Wang J, et al. Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator. Science (New York, N.Y.). 329: 1068-71. PMID 20798317 DOI: 10.1126/science.1192428  0.52
2010 Govin J, Dorsey J, Gaucher J, Rousseaux S, Khochbin S, Berger SL. Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis. Genes & Development. 24: 1772-86. PMID 20713519 DOI: 10.1101/gad.1954910  0.52
2010 Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science (New York, N.Y.). 329: 1201-5. PMID 20647423 DOI: 10.1126/science.1191241  0.52
2010 Berger SL. Keeping p53 in check: a high-stakes balancing act. Cell. 142: 17-9. PMID 20603009 DOI: 10.1016/j.cell.2010.06.026  0.52
2010 Govin J, Schug J, Krishnamoorthy T, Dorsey J, Khochbin S, Berger SL. Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae. Nucleic Acids Research. 38: 4599-606. PMID 20375100 DOI: 10.1093/nar/gkq218  0.52
2010 Placek BJ, Berger SL. Chromatin dynamics during herpes simplex virus-1 lytic infection. Biochimica Et Biophysica Acta. 1799: 223-7. PMID 20139038 DOI: 10.1016/j.bbagrm.2010.01.012  0.52
2010 Huang J, Dorsey J, Chuikov S, Pérez-Burgos L, Zhang X, Jenuwein T, Reinberg D, Berger SL. G9a and Glp methylate lysine 373 in the tumor suppressor p53. The Journal of Biological Chemistry. 285: 9636-41. PMID 20118233 DOI: 10.1074/jbc.M109.062588  0.52
2010 Kozak ML, Chavez A, Dang W, Berger SL, Ashok A, Guo X, Johnson FB. Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. The Embo Journal. 29: 158-70. PMID 19875981 DOI: 10.1038/emboj.2009.314  0.52
2010 Huang J, Dorsey J, Chuikov S, Pérez-Burgos L, Zhang X, Jenuwein T, Reinberg D, Berger SL. G9a and Glp methylate lysine 373 in the tumor suppressor p53 (Journal of Biological Chemistry (2010) 285, (9636-9641) DOI: 10.1074/jbc.A109.062588) Journal of Biological Chemistry. 285: 18122.  0.52
2009 Sanders BD, Jackson B, Brent M, Taylor AM, Dang W, Berger SL, Schreiber SL, Howitz K, Marmorstein R. Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorganic & Medicinal Chemistry. 17: 7031-41. PMID 19734050 DOI: 10.1016/j.bmc.2009.07.073  0.52
2009 Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature. 459: 802-7. PMID 19516333 DOI: 10.1038/nature08085  0.52
2009 Govin J, Berger SL. Genome reprogramming during sporulation. The International Journal of Developmental Biology. 53: 425-32. PMID 19412896 DOI: 10.1387/ijdb.082687jg  0.52
2009 Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes & Development. 23: 781-3. PMID 19339683 DOI: 10.1101/gad.1787609  0.52
2009 Lin YY, Lu JY, Zhang J, Walter W, Dang W, Wan J, Tao SC, Qian J, Zhao Y, Boeke JD, Berger SL, Zhu H. Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell. 136: 1073-84. PMID 19303850 DOI: 10.1016/j.cell.2009.01.033  0.52
2009 Placek BJ, Huang J, Kent JR, Dorsey J, Rice L, Fraser NW, Berger SL. The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1. Journal of Virology. 83: 1416-21. PMID 19004946 DOI: 10.1128/JVI.01276-08  0.52
2008 Berger SL. Out of the jaws of death: PRMT5 steers p53. Nature Cell Biology. 10: 1389-90. PMID 19043433 DOI: 10.1038/ncb1208-1389  0.52
2008 Zediak VP, Berger SL. Hit and run: transient deubiquitylase activity in a chromatin-remodeling complex. Molecular Cell. 31: 773-4. PMID 18922460 DOI: 10.1016/j.molcel.2008.09.005  0.52
2008 Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, ... ... Berger SL, et al. The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes & Development. 22: 2664-76. PMID 18832071 DOI: 10.1101/gad.1703008  0.52
2008 Huang J, Berger SL. The emerging field of dynamic lysine methylation of non-histone proteins. Current Opinion in Genetics & Development. 18: 152-8. PMID 18339539 DOI: 10.1016/j.gde.2008.01.012  0.52
2008 Walter W, Clynes D, Tang Y, Marmorstein R, Mellor J, Berger SL. 14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation. Molecular and Cellular Biology. 28: 2840-9. PMID 18268010 DOI: 10.1128/MCB.01457-07  0.52
2008 Zhang XY, Varthi M, Sykes SM, Phillips C, Warzecha C, Zhu W, Wyce A, Thorne AW, Berger SL, McMahon SB. The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Molecular Cell. 29: 102-11. PMID 18206973 DOI: 10.1016/j.molcel.2007.12.015  0.52
2007 Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, Pillus L, Reinberg D, Shi Y, Shiekhattar R, Shilatifard A, Workman J, Zhang Y. New nomenclature for chromatin-modifying enzymes. Cell. 131: 633-6. PMID 18022353 DOI: 10.1016/j.cell.2007.10.039  0.52
2007 Ingvarsdottir K, Edwards C, Lee MG, Lee JS, Schultz DC, Shilatifard A, Shiekhattar R, Berger SL. Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Molecular and Cellular Biology. 27: 7856-64. PMID 17875926 DOI: 10.1128/MCB.00801-07  0.52
2007 Huang J, Sengupta R, Espejo AB, Lee MG, Dorsey JA, Richter M, Opravil S, Shiekhattar R, Bedford MT, Jenuwein T, Berger SL. p53 is regulated by the lysine demethylase LSD1. Nature. 449: 105-8. PMID 17805299 DOI: 10.1038/nature06092  0.52
2007 Wyce A, Xiao T, Whelan KA, Kosman C, Walter W, Eick D, Hughes TR, Krogan NJ, Strahl BD, Berger SL. H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Molecular Cell. 27: 275-88. PMID 17643376 DOI: 10.1016/j.molcel.2007.01.035  0.52
2007 Berger SL. The complex language of chromatin regulation during transcription. Nature. 447: 407-12. PMID 17522673 DOI: 10.1038/nature05915  0.52
2007 Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, ... ... Berger SL, et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 446: 806-10. PMID 17314980 DOI: 10.1038/nature05649  0.52
2007 Chen Q, Lin L, Smith S, Huang J, Berger SL, Zhou J. CTCF-dependent chromatin boundary element between the latency-associated transcript and ICP0 promoters in the herpes simplex virus type 1 genome. Journal of Virology. 81: 5192-201. PMID 17267480 DOI: 10.1128/JVI.02447-06  0.52
2006 Zeng PY, Vakoc CR, Chen ZC, Blobel GA, Berger SL. In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. Biotechniques. 41: 694, 696, 698. PMID 17191611 DOI: 10.2144/000112297  0.52
2006 Huang J, Perez-Burgos L, Placek BJ, Sengupta R, Richter M, Dorsey JA, Kubicek S, Opravil S, Jenuwein T, Berger SL. Repression of p53 activity by Smyd2-mediated methylation. Nature. 444: 629-32. PMID 17108971 DOI: 10.1038/nature05287  0.52
2006 Zeng PY, Berger SL. LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation. Cancer Research. 66: 10701-8. PMID 17108107 DOI: 10.1158/0008-5472.CAN-06-0999  0.52
2006 Krishnamoorthy T, Chen X, Govin J, Cheung WL, Dorsey J, Schindler K, Winter E, Allis CD, Guacci V, Khochbin S, Fuller MT, Berger SL. Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes & Development. 20: 2580-92. PMID 16980586 DOI: 10.1101/gad.1457006  0.52
2006 Vermeulen M, Walter W, Le Guezennec X, Kim J, Edayathumangalam RS, Lasonder E, Luger K, Roeder RG, Logie C, Berger SL, Stunnenberg HG. A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Molecular and Cellular Biology. 26: 5226-36. PMID 16809761 DOI: 10.1128/MCB.00440-06  0.52
2006 Huang J, Kent JR, Placek B, Whelan KA, Hollow CM, Zeng PY, Fraser NW, Berger SL. Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1. Journal of Virology. 80: 5740-6. PMID 16731913 DOI: 10.1128/JVI.00169-06  0.52
2006 Nathan D, Ingvarsdottir K, Sterner DE, Bylebyl GR, Dokmanovic M, Dorsey JA, Whelan KA, Krsmanovic M, Lane WS, Meluh PB, Johnson ES, Berger SL. Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes & Development. 20: 966-76. PMID 16598039 DOI: 10.1101/gad.1404206  0.52
2006 Emre NC, Berger SL. Histone post-translational modifications regulate transcription and silent chromatin in Saccharomyces cerevisiae. Ernst Schering Research Foundation Workshop. 127-53. PMID 16568953  0.52
2006 Nayak V, Zhao K, Wyce A, Schwartz MF, Lo WS, Berger SL, Marmorstein R. Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family. Structure (London, England : 1993). 14: 477-85. PMID 16531232 DOI: 10.1016/j.str.2005.12.008  0.52
2006 Sterner DE, Nathan D, Reindle A, Johnson ES, Berger SL. Sumoylation of the yeast Gcn5 protein. Biochemistry. 45: 1035-42. PMID 16411780 DOI: 10.1021/bi051624q  0.52
2005 Cheung WL, Turner FB, Krishnamoorthy T, Wolner B, Ahn SH, Foley M, Dorsey JA, Peterson CL, Berger SL, Allis CD. Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae. Current Biology : Cb. 15: 656-60. PMID 15823538 DOI: 10.1016/j.cub.2005.02.049  0.52
2005 Emre NC, Ingvarsdottir K, Wyce A, Wood A, Krogan NJ, Henry KW, Li K, Marmorstein R, Greenblatt JF, Shilatifard A, Berger SL. Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Molecular Cell. 17: 585-94. PMID 15721261 DOI: 10.1016/j.molcel.2005.01.007  0.52
2005 Lo WS, Gamache ER, Henry KW, Yang D, Pillus L, Berger SL. Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms. The Embo Journal. 24: 997-1008. PMID 15719021 DOI: 10.1038/sj.emboj.7600577  0.52
2005 Ingvarsdottir K, Krogan NJ, Emre NC, Wyce A, Thompson NJ, Emili A, Hughes TR, Greenblatt JF, Berger SL. H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Molecular and Cellular Biology. 25: 1162-72. PMID 15657441 DOI: 10.1128/MCB.25.3.1162-1172.2005  0.52
2004 Emre NC, Berger SL. Histone H2B ubiquitylation and deubiquitylation in genomic regulation. Cold Spring Harbor Symposia On Quantitative Biology. 69: 289-99. PMID 16117661 DOI: 10.1101/sqb.2004.69.289  0.52
2004 Zhou J, Berger SL. Good fences make good neighbors: barrier elements and genomic regulation. Molecular Cell. 16: 500-2. PMID 15546609 DOI: 10.1016/j.molcel.2004.11.005  0.52
2004 Kent JR, Zeng PY, Atanasiu D, Gardner J, Fraser NW, Berger SL. During lytic infection herpes simplex virus type 1 is associated with histones bearing modifications that correlate with active transcription Journal of Virology. 78: 10178-10186. PMID 15331750 DOI: 10.1128/JVI.78.18.10178-10186.2004  0.52
2004 Wyce A, Henry KW, Berger SL. H2B ubiquitylation and de-ubiquitylation in gene activation. Novartis Foundation Symposium. 259: 63-73; discussion 73. PMID 15171247  0.52
2004 Lo WS, Henry KW, Schwartz MF, Berger SL. Histone modification patterns during gene activation. Methods in Enzymology. 377: 130-53. PMID 14979022 DOI: 10.1016/S0076-6879(03)77007-4  0.52
2004 Hiroi H, Christenson LK, Chang L, Sammel MD, Berger SL, Strauss JF. Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (stAR) locus associated with stAR transcription. Molecular Endocrinology (Baltimore, Md.). 18: 791-806. PMID 14726488 DOI: 10.1210/me.2003-0305  0.52
2003 Nathan D, Sterner DE, Berger SL. Histone modifications: Now summoning sumoylation. Proceedings of the National Academy of Sciences of the United States of America. 100: 13118-20. PMID 14597707 DOI: 10.1073/pnas.2436173100  0.52
2003 Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA, Berger SL. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes & Development. 17: 2648-63. PMID 14563679 DOI: 10.1101/gad.1144003  0.52
2003 Clements A, Poux AN, Lo WS, Pillus L, Berger SL, Marmorstein R. Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Molecular Cell. 12: 461-73. PMID 14536085 DOI: 10.1016/S1097-2765(03)00288-0  0.52
2003 Barlev NA, Emelyanov AV, Castagnino P, Zegerman P, Bannister AJ, Sepulveda MA, Robert F, Tora L, Kouzarides T, Birshtein BK, Berger SL. A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. Molecular and Cellular Biology. 23: 6944-57. PMID 12972612 DOI: 10.1128/MCB.23.19.6944-6957.2003  0.52
2002 Sterner DE, Belotserkovskaya R, Berger SL. SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription. Proceedings of the National Academy of Sciences of the United States of America. 99: 11622-7. PMID 12186975 DOI: 10.1073/pnas.182021199  0.52
2002 Henry KW, Berger SL. Trans-tail histone modifications: wedge or bridge? Nature Structural Biology. 9: 565-6. PMID 12145643 DOI: 10.1038/nsb0802-565  0.52
2002 Berger SL. Histone modifications in transcriptional regulation. Current Opinion in Genetics & Development. 12: 142-8. PMID 11893486 DOI: 10.1016/S0959-437X(02)00279-4  0.52
2002 Sterner DE, Wang X, Bloom MH, Simon GM, Berger SL. The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex. The Journal of Biological Chemistry. 277: 8178-86. PMID 11777910 DOI: 10.1074/jbc.M108601200  0.52
2001 Barlev NA, Liu L, Chehab NH, Mansfield K, Harris KG, Halazonetis TD, Berger SL. Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases Molecular Cell. 8: 1243-1254. PMID 11779500 DOI: 10.1016/S1097-2765(01)00414-2  0.52
2001 Tsavachidou D, Podrzucki W, Seykora J, Berger SL. Gene array analysis reveals changes in peripheral nervous system gene expression following stimuli that result in reactivation of latent herpes simplex virus type 1: Induction of transcription factor Bcl-3 Journal of Virology. 75: 9909-9917. PMID 11559823 DOI: 10.1128/JVI.75.20.9909-9917.2001  0.52
2001 Berger SL, Felsenfeld G. Chromatin goes global. Molecular Cell. 8: 263-8. PMID 11545729 DOI: 10.1016/S1097-2765(01)00330-6  0.52
2001 Lo WS, Duggan L, Emre NC, Belotserkovskya R, Lane WS, Shiekhattar R, Berger SL. Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science (New York, N.Y.). 293: 1142-6. PMID 11498592 DOI: 10.1126/science.1062322  0.52
2001 Marmorstein R, Berger SL. Structure and function of bromodomains in chromatin-regulating complexes. Gene. 272: 1-9. PMID 11470504 DOI: 10.1016/S0378-1119(01)00519-4  0.52
2001 Berger SL. An embarrassment of niches: The many covalent modifications of histones in transcriptional regulation Oncogene. 20: 3007-3013. PMID 11420715 DOI: 10.1038/sj.onc.1204324  0.52
2001 Berger SL. The histone modification circus Science. 292: 64-65. PMID 11294220  0.52
2000 Yan Y, Barlev NA, Haley RH, Berger SL, Marmorstein R. Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Molecular Cell. 6: 1195-205. PMID 11106757  0.52
2000 Berger SL. Gene regulation: Local or global? Nature. 408: 412-415. PMID 11100706 DOI: 10.1038/35044160  0.52
2000 Lo WS, Trievel RC, Rojas JR, Duggan L, Hsu JY, Allis CD, Marmorstein R, Berger SL. Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Molecular Cell. 5: 917-26. PMID 10911986  0.52
2000 Sterner DE, Berger SL. Acetylation of histones and transcription-related factors Microbiology and Molecular Biology Reviews. 64: 435-459. PMID 10839822  0.52
2000 Anafi M, Yang YF, Barlev NA, Govindan MV, Berger SL, Butt TR, Walfish PG. GCN5 and ADA adaptor proteins regulate triiodothyronine/GRIP1 and SRC-1 coactivator-dependent gene activation by the human thyroid hormone receptor. Molecular Endocrinology (Baltimore, Md.). 14: 718-32. PMID 10809234 DOI: 10.1210/mend.14.5.0457  0.52
2000 Belotserkovskaya R, Sterner DE, Deng M, Sayre MH, Lieberman PM, Berger SL. Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters Molecular and Cellular Biology. 20: 634-647. PMID 10611242 DOI: 10.1128/MCB.20.2.634-647.2000  0.52
1999 Grant PA, Berger SL, Workman JL. Identification and analysis of native nucleosomal histone acetyltransferase complexes. Methods in Molecular Biology (Clifton, N.J.). 119: 311-7. PMID 10804521 DOI: 10.1385/1-59259-681-9:311  0.52
1999 Belotserkovskaya R, Berger SL. Interplay between chromatin modifying and remodeling complexes in transcriptional regulation Critical Reviews in Eukaryotic Gene Expression. 9: 221-230. PMID 10651239  0.52
1999 Eberharter A, Sterner DE, Schieltz D, Hassan A, Yates JR, Berger SL, Workman JL. The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae. Molecular and Cellular Biology. 19: 6621-31. PMID 10490601  0.52
1999 Rojas JR, Trievel RC, Zhou J, Mo Y, Li X, Berger SL, Allis CD, Marmorstein R. Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature. 401: 93-8. PMID 10485713 DOI: 10.1038/43487  0.52
1999 Massari ME, Grant PA, Pray-Grant MG, Berger SL, Workman JL, Murre C. A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Molecular Cell. 4: 63-73. PMID 10445028 DOI: 10.1016/S1097-2765(00)80188-4  0.52
1999 Grant PA, Berger SL. Histone acetyltransferase complexes. Seminars in Cell & Developmental Biology. 10: 169-77. PMID 10441070 DOI: 10.1006/scdb.1999.0298  0.52
1999 Trievel RC, Rojas JR, Sterner DE, Venkataramani RN, Wang L, Zhou J, Allis CD, Berger SL, Marmorstein R. Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator. Proceedings of the National Academy of Sciences of the United States of America. 96: 8931-6. PMID 10430873 DOI: 10.1073/pnas.96.16.8931  0.52
1999 Berger SL. Gene activation by histone and factor acetyltransferases Current Opinion in Cell Biology. 11: 336-341. PMID 10395565 DOI: 10.1016/S0955-0674(99)80046-5  0.52
1999 Clements A, Rojas JR, Trievel RC, Wang L, Berger SL, Marmorstein R. Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A. The Embo Journal. 18: 3521-32. PMID 10393169 DOI: 10.1093/emboj/18.13.3521  0.52
1999 Tanner KG, Trievel RC, Kuo MH, Howard RM, Berger SL, Allis CD, Marmorstein R, Denu JM. Catalytic mechanism and function of invariant glutamic acid 173 from the histone acetyltransferase GCN5 transcriptional coactivator. The Journal of Biological Chemistry. 274: 18157-60. PMID 10373413 DOI: 10.1074/jbc.274.26.18157  0.52
1999 Barlev NA, Workman JL, Berger SL. Analysis of activity and regulation of hGcn5, a human histone acetyltransferase. Methods in Enzymology. 304: 696-715. PMID 10372391 DOI: 10.1016/S0076-6879(99)04042-2  0.52
1999 Liu L, Scolnick DM, Trievel RC, Zhang HB, Marmorstein R, Halazonetis TD, Berger SL. p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Molecular and Cellular Biology. 19: 1202-9. PMID 9891054  0.52
1998 Grant PA, Sterner DE, Duggan LJ, Workman JL, Berger SL. The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. Trends in Cell Biology. 8: 193-7. PMID 9695838 DOI: 10.1016/S0962-8924(98)01263-X  0.52
1998 Gregory PD, Schmid A, Zavari M, Liu L, Berger SL, Hörz W. Absence of Gcn5 HAT activity defines a novel state in the opening of chromatin at the PHO5 promoter in yeast Molecular Cell. 1: 495-505. PMID 9660934  0.52
1998 Smith ER, Belote JM, Schiltz RL, Yang XJ, Moore PA, Berger SL, Nakatani Y, Allis CD. Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members. Nucleic Acids Research. 26: 2948-54. PMID 9611240 DOI: 10.1093/nar/26.12.2948  0.52
1998 Wang L, Liu L, Berger SL. Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo Genes and Development. 12: 640-653. PMID 9499400  0.52
1998 Barlev NA, Poltoratsky V, Owen-Hughes T, Ying C, Liu L, Workman JL, Berger SL. Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Molecular and Cellular Biology. 18: 1349-58. PMID 9488450  0.52
1998 Li R, Yu DS, Tanaka M, Zheng L, Berger SL, Stillman B. Activation of chromosomal DNA replication in Saccharomyces cerevisiae by acidic transcriptional activation domains Molecular and Cellular Biology. 18: 1296-1302. PMID 9488444  0.52
1998 Tal-Singer R, Podrzucki W, Lasner TM, Skokotas A, Leary JJ, Fraser NW, Berger SL. Use of differential display reverse transcription-PCR to reveal cellular changes during stimuli that result in herpes simplex virus type 1 reactivation from latency: Upregulation of immediate-early cellular response genes TIS7, interferon, and interferon regulatory factor-1 Journal of Virology. 72: 1252-1261. PMID 9445025  0.52
1997 Scolnick DM, Chehab NH, Stavridi ES, Lien MC, Caruso L, Moran E, Berger SL, Halazonetis TD. CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein. Cancer Research. 57: 3693-6. PMID 9288775  0.52
1997 Candau R, Scolnick DM, Darpino P, Ying CY, Halazonetis TD, Berger SL. Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity. Oncogene. 15: 807-16. PMID 9266967 DOI: 10.1038/sj.onc.1201244  0.52
1997 Tal-Singer R, Lasner TM, Podrzucki W, Skokotas A, Leary JJ, Berger SL, Fraser NW. Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue cultures Journal of Virology. 71: 5268-5276. PMID 9188595  0.52
1997 Carter KC, Wang L, Shell BK, Zamir I, Berger SL, Moore PA. The human transcriptional adaptor genes TADA2L and GCN5L2 colocalize to chromosome 17q12-q21 and display a similar tissue expression pattern Genomics. 40: 497-500. PMID 9073520 DOI: 10.1006/geno.1996.4605  0.52
1997 Candau R, Zhou J, Allis CD, Berger SL. Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo Embo Journal. 16: 555-565. PMID 9034338 DOI: 10.1093/emboj/16.3.555  0.52
1997 Wang L, Mizzen C, Ying C, Candau R, Barlev N, Brownell J, Allis CD, Berger SL. Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation Molecular and Cellular Biology. 17: 519-527. PMID 8972232  0.52
1996 Mizzen CA, Yang XJ, Kokubo T, Brownell JE, Bannister AJ, Owen-Hughes T, Workman J, Wang L, Berger SL, Kouzarides T, Nakatani Y, Allis CD. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity Cell. 87: 1261-1270. PMID 8980232 DOI: 10.1016/S0092-8674(00)81821-8  0.52
1996 Candau R, Berger SL. Structural and functional analysis of yeast putative adaptors: Evidence for an adaptor complex in vivo Journal of Biological Chemistry. 271: 5237-5245. PMID 8617808  0.52
1996 Candau R, Moore PA, Wang L, Barlev N, Ying CY, Rosen CA, Berger SL. Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5 Molecular and Cellular Biology. 16: 593-602. PMID 8552087  0.52
1995 Barley NA, Candau R, Wang L, Darpino P, Silverman N, Berger SL. Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein Journal of Biological Chemistry. 270: 19337-19344. PMID 7642611 DOI: 10.1074/jbc.270.33.19337  0.52
1995 Wang L, Turcotte B, Guarente L, Berger SL. The acidic transcriptional activation domains of herpes virus VP16 and yeast HAP4 have different co-factor requirements Gene. 158: 163-170. PMID 7607537 DOI: 10.1016/0378-1119(95)00126-Q  0.52
1994 Berger SL, Meselson M. Production and cleavage of Drosophila hsp70 transcripts extending beyond the polyadenylation site Nucleic Acids Research. 22: 3218-3225. PMID 8065938 DOI: 10.1093/nar/22.15.3218  0.52
1994 Marcus GA, Silverman N, Berger SL, Horiuchi J, Guarente L. Functional similarity and physical association between GCN5 and ADA2: Putative transcriptional adaptors Embo Journal. 13: 4807-4815. PMID 7957049  0.52
1992 Berger SL, Piña B, Silverman N, Marcus GA, Agapite J, Regier JL, Triezenberg SJ, Guarente L. Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains Cell. 70: 251-265. PMID 1638630 DOI: 10.1016/0092-8674(92)90100-Q  0.52
1990 Berger SL, Cress WD, Cress A, Triezenberg SJ, Guarente L. Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors. Cell. 61: 1199-208. PMID 2163758 DOI: 10.1016/0092-8674(90)90684-7  0.52
1987 Tang WJ, Berger SL, Triezenberg SJ, Folk WR. Nucleotides in the polyomavirus enhancer that control viral transcription and DNA replication. Molecular and Cellular Biology. 7: 1681-90. PMID 3037332  0.52
1985 Berger SL, Folk WR. Differential activation of RNA polymerase III-transcribed genes by the polyomavirus enhancer and the adenovirus E1A gene products. Nucleic Acids Research. 13: 1413-28. PMID 2987823 DOI: 10.1093/nar/13.4.1413  0.52
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