Stephen A. Liebhaber - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Genetics, Molecular Biology, Endocrinology Biology

171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ji X, Park JW, Bahrami-Samani E, Lin L, Duncan-Lewis C, Pherribo G, Xing Y, Liebhaber SA. αCP binding to a cytosine-rich subset of polypyrimidine tracts drives a novel pathway of cassette exon splicing in the mammalian transcriptome. Nucleic Acids Research. PMID 26896798 DOI: 10.1093/nar/gkw088  0.76
2016 Tsai YC, Cooke NE, Liebhaber SA. Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster. Nucleic Acids Research. PMID 26893355 DOI: 10.1093/nar/gkw090  0.76
2016 Kini HK, Silverman IM, Ji X, Gregory BD, Liebhaber SA. Cytoplasmic poly(A) binding protein-1 binds to genomically encoded sequences within mammalian mRNAs. Rna (New York, N.Y.). 22: 61-74. PMID 26554031 DOI: 10.1261/rna.053447.115  0.72
2015 Sobrier ML, Tsai YC, Pérez C, Leheup B, Bouceba T, Duquesnoy P, Copin B, Sizova D, Penzo A, Stanger BZ, Cooke NE, Liebhaber SA, Amselem S. Functional characterization of a human POU1F1 mutation associated with isolated growth hormone deficiency (IGHD): a novel etiology for IGHD. Human Molecular Genetics. PMID 26612202 DOI: 10.1093/hmg/ddv486  0.76
2015 Ghanem LR, Kromer A, Silverman IM, Chatterji P, Traxler E, Penzo-Mendez A, Weiss MJ, Stanger BZ, Liebhaber SA. The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Molecular and Cellular Biology. 36: 304-19. PMID 26527618 DOI: 10.1128/MCB.00936-15  0.76
2015 Pereira FJ, Teixeira A, Kong J, Barbosa C, Silva AL, Marques-Ramos A, Liebhaber SA, Romão L. Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity. Nucleic Acids Research. PMID 26068473 DOI: 10.1093/nar/gkv588  0.76
2015 Ho Y, Cooke NE, Liebhaber SA. An autoregulatory pathway establishes the definitive chromatin conformation at the pit-1 locus. Molecular and Cellular Biology. 35: 1523-32. PMID 25691665 DOI: 10.1128/MCB.01283-14  0.76
2015 Yoo EJ, Brown CD, Tsai YC, Cooke NE, Liebhaber SA. Autonomous actions of the human growth hormone long-range enhancer. Nucleic Acids Research. 43: 2091-101. PMID 25662214 DOI: 10.1093/nar/gkv093  0.76
2014 Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, et al. Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 111: E4946-53. PMID 25369933 DOI: 10.1073/pnas.1407079111  0.76
2014 Tsai YC, Cooke NE, Liebhaber SA. Tissue specific CTCF occupancy and boundary function at the human growth hormone locus. Nucleic Acids Research. 42: 4906-21. PMID 24561805 DOI: 10.1093/nar/gku139  0.76
2014 Ghanem LR, Chatterji P, Liebhaber SA. Specific enrichment of the RNA-binding proteins PCBP1 and PCBP2 in chief cells of the murine gastric mucosa. Gene Expression Patterns : Gep. 14: 78-87. PMID 24480778 DOI: 10.1016/j.gep.2014.01.004  0.76
2014 Kini HK, Kong J, Liebhaber SA. Cytoplasmic poly(A) binding protein C4 serves a critical role in erythroid differentiation. Molecular and Cellular Biology. 34: 1300-9. PMID 24469397 DOI: 10.1128/MCB.01683-13  0.76
2013 Yoo EJ, Cooke NE, Liebhaber SA. Identification of a secondary promoter within the human B cell receptor component gene hCD79b. The Journal of Biological Chemistry. 288: 18353-65. PMID 23649625 DOI: 10.1074/jbc.M113.461988  0.76
2013 Ji X, Wan J, Vishnu M, Xing Y, Liebhaber SA. αCP Poly(C) binding proteins act as global regulators of alternative polyadenylation. Molecular and Cellular Biology. 33: 2560-73. PMID 23629627 DOI: 10.1128/MCB.01380-12  0.76
2013 Ho Y, Shewchuk BM, Liebhaber SA, Cooke NE. Distinct chromatin configurations regulate the initiation and the maintenance of hGH gene expression. Molecular and Cellular Biology. 33: 1723-34. PMID 23428872 DOI: 10.1128/MCB.01166-12  0.76
2013 Nuytens K, Gantois I, Stijnen P, Iscru E, Laeremans A, Serneels L, Van Eylen L, Liebhaber SA, Devriendt K, Balschun D, Arckens L, Creemers JW, D'Hooge R. Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice. Neurobiology of Disease. 51: 144-51. PMID 23153818 DOI: 10.1016/j.nbd.2012.11.004  0.76
2012 Fleetwood MR, Ho Y, Cooke NE, Liebhaber SA. DNase I hypersensitive site II of the human growth hormone locus control region mediates an essential and distinct long-range enhancer function. The Journal of Biological Chemistry. 287: 25454-65. PMID 22669946 DOI: 10.1074/jbc.M112.365825  0.76
2012 Yoo EJ, Cooke NE, Liebhaber SA. An RNA-independent linkage of noncoding transcription to long-range enhancer function. Molecular and Cellular Biology. 32: 2020-9. PMID 22431516 DOI: 10.1128/MCB.06650-11  0.76
2012 Natsuizaka M, Naganuma S, Kagawa S, Ohashi S, Ahmadi A, Subramanian H, Chang S, Nakagawa KJ, Ji X, Liebhaber SA, Klein-Szanto AJ, Nakagawa H. Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2620-30. PMID 22415309 DOI: 10.1096/fj.11-198598  0.76
2012 Peixeiro I, Inácio Â, Barbosa C, Silva AL, Liebhaber SA, Romão L. Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations. Nucleic Acids Research. 40: 1160-73. PMID 21989405 DOI: 10.1093/nar/gkr820  0.76
2011 Ji X, Kong J, Liebhaber SA. An RNA-protein complex links enhanced nuclear 3' processing with cytoplasmic mRNA stabilization. The Embo Journal. 30: 2622-33. PMID 21623344 DOI: 10.1038/emboj.2011.171  0.76
2011 Vishnu MR, Sumaroka M, Klein PS, Liebhaber SA. The poly(rC)-binding protein alphaCP2 is a noncanonical factor in X. laevis cytoplasmic polyadenylation. Rna (New York, N.Y.). 17: 944-56. PMID 21444632 DOI: 10.1261/rna.2587411  0.76
2011 Ho Y, Liebhaber SA, Cooke NE. The role of the hGH locus control region in somatotrope restriction of hGH-N gene expression. Molecular Endocrinology (Baltimore, Md.). 25: 877-84. PMID 21415161 DOI: 10.1210/me.2010-0411  0.76
2010 Chiefari E, Iiritano S, Paonessa F, Le Pera I, Arcidiacono B, Filocamo M, Foti D, Liebhaber SA, Brunetti A. Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes. Nature Communications. 1: 40. PMID 20975707 DOI: 10.1038/ncomms1040  0.76
2010 Sizova D, Ho Y, Cooke NE, Liebhaber SA. Research resource: T-antigen transformation of pituitary cells captures three novel cell lines in the Pit-1 lineage. Molecular Endocrinology (Baltimore, Md.). 24: 2232-40. PMID 20829390 DOI: 10.1210/me.2010-0235  0.76
2010 Kini HK, Vishnu MR, Liebhaber SA. Too much PABP, too little translation. The Journal of Clinical Investigation. 120: 3090-3. PMID 20739750 DOI: 10.1172/JCI44091  0.76
2010 Eiring AM, Harb JG, Neviani P, Garton C, Oaks JJ, Spizzo R, Liu S, Schwind S, Santhanam R, Hickey CJ, Becker H, Chandler JC, Andino R, Cortes J, Hokland P, ... ... Liebhaber SA, et al. miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell. 140: 652-65. PMID 20211135 DOI: 10.1016/j.cell.2010.01.007  0.76
2009 Waggoner SA, Johannes GJ, Liebhaber SA. Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest. The Journal of Biological Chemistry. 284: 9039-49. PMID 19211566 DOI: 10.1074/jbc.M806986200  0.76
2009 Hamanaka RB, Bobrovnikova-Marjon E, Ji X, Liebhaber SA, Diehl JA. PERK-dependent regulation of IAP translation during ER stress Oncogene. 28: 910-920. PMID 19029953 DOI: 10.1038/onc.2008.428  0.76
2008 Hayden BY, Heilbronner SR, Nair AC, Platt ML. Cognitive influences on risk-seeking by rhesus macaques. Judgment and Decision Making. 3: 389-395. PMID 19844596 DOI: 10.1017/S135583820202808X  0.76
2008 Rudnick SI, Swaminathan J, Sumaroka M, Liebhaber S, Gewirtz AM. Effects of local mRNA structure on posttranscriptional gene silencing. Proceedings of the National Academy of Sciences of the United States of America. 105: 13787-92. PMID 18784366 DOI: 10.1073/pnas.0805781105  0.76
2008 Ho Y, Tadevosyan A, Liebhaber SA, Cooke NE. The juxtaposition of a promoter with a locus control region transcriptional domain activates gene expression. Embo Reports. 9: 891-8. PMID 18636089 DOI: 10.1038/embor.2008.126  0.76
2008 Young RM, Wang SJ, Gordan JD, Ji X, Liebhaber SA, Simon MC. Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism. The Journal of Biological Chemistry. 283: 16309-19. PMID 18430730 DOI: 10.1074/jbc.M710079200  0.76
2008 Silva AL, Ribeiro P, Inácio A, Liebhaber SA, Romão L. Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay. Rna (New York, N.Y.). 14: 563-76. PMID 18230761 DOI: 10.1261/rna.815108  0.76
2007 Roullet M, Sargent R, Pasha T, Cajiao I, Elstrom R, Smith T, Liebhaber S, Zhang P, Bagg A. ZAP70 expression assessed by immunohistochemistry on peripheral blood: a simple prognostic assay for patients with chronic lymphocytic leukemia. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 15: 471-6. PMID 18091393 DOI: 10.1097/01.pai.0000213152.41440.34  0.76
2007 Hiroki T, Liebhaber SA, Cooke NE. An intronic locus control region plays an essential role in the establishment of an autonomous hepatic chromatin domain for the human vitamin D-binding protein gene. Molecular and Cellular Biology. 27: 7365-80. PMID 17785430 DOI: 10.1128/MCB.00331-07  0.76
2007 Kimura AP, Sizova D, Handwerger S, Cooke NE, Liebhaber SA. Epigenetic activation of the human growth hormone gene cluster during placental cytotrophoblast differentiation. Molecular and Cellular Biology. 27: 6555-68. PMID 17636034 DOI: 10.1128/MCB.00273-07  0.76
2007 Kong J, Liebhaber SA. A cell type-restricted mRNA surveillance pathway triggered by ribosome extension into the 3' untranslated region. Nature Structural & Molecular Biology. 14: 670-6. PMID 17572684 DOI: 10.1038/nsmb1256  0.76
2007 Chendrimada TP, Finn KJ, Ji X, Baillat D, Gregory RI, Liebhaber SA, Pasquinelli AE, Shiekhattar R. MicroRNA silencing through RISC recruitment of eIF6. Nature. 447: 823-8. PMID 17507929 DOI: 10.1038/nature05841  0.76
2007 Ji X, Kong J, Carstens RP, Liebhaber SA. The 3' untranslated region complex involved in stabilization of human alpha-globin mRNA assembles in the nucleus and serves an independent role as a splice enhancer. Molecular and Cellular Biology. 27: 3290-302. PMID 17325043 DOI: 10.1128/MCB.02289-05  0.76
2007 Cajiao I, Sargent R, Elstrom R, Cooke NE, Bagg A, Liebhaber SA. Igbeta(CD79b) mRNA expression in chronic lymphocytic leukaemia cells correlates with immunoglobulin heavy chain gene mutational status but does not serve as an independent predictor of clinical severity. American Journal of Hematology. 82: 712-20. PMID 17315213 DOI: 10.1002/ajh.20885  0.76
2006 Silva AL, Pereira FJ, Morgado A, Kong J, Martins R, Faustino P, Liebhaber SA, Romão L. The canonical UPF1-dependent nonsense-mediated mRNA decay is inhibited in transcripts carrying a short open reading frame independent of sequence context. Rna (New York, N.Y.). 12: 2160-70. PMID 17077274 DOI: 10.1261/rna.201406  0.76
2006 Shewchuk BM, Ho Y, Liebhaber SA, Cooke NE. A single base difference between Pit-1 binding sites at the hGH promoter and locus control region specifies distinct Pit-1 conformations and functions. Molecular and Cellular Biology. 26: 6535-46. PMID 16914737 DOI: 10.1128/MCB.00267-06  0.76
2006 Ho Y, Elefant F, Liebhaber SA, Cooke NE. Locus control region transcription plays an active role in long-range gene activation. Molecular Cell. 23: 365-75. PMID 16885026 DOI: 10.1016/j.molcel.2006.05.041  0.76
2006 Kong J, Sumaroka M, Eastmond DL, Liebhaber SA. Shared stabilization functions of pyrimidine-rich determinants in the erythroid 15-lipoxygenase and alpha-globin mRNAs. Molecular and Cellular Biology. 26: 5603-14. PMID 16847316 DOI: 10.1128/MCB.01845-05  0.76
2006 Yoo EJ, Cajiao I, Kim JS, Kimura AP, Zhang A, Cooke NE, Liebhaber SA. Tissue-specific chromatin modifications at a multigene locus generate asymmetric transcriptional interactions. Molecular and Cellular Biology. 26: 5569-79. PMID 16847312 DOI: 10.1128/MCB.00405-06  0.76
2006 Hiroki T, Song YH, Liebhaber SA, Cooke NE. The human vitamin D-binding protein gene contains locus control determinants sufficient for autonomous activation in hepatic chromatin. Nucleic Acids Research. 34: 2154-65. PMID 16648359 DOI: 10.1093/nar/gkl174  0.76
2006 Ho Y, Elefant F, Liebhaber SA, Cooke NE. Locus Control Region Transcription Plays an Active Role in Long-Range Gene Activation (DOI:10.1016/j.molcel.2006.05.041) Molecular Cell. 23: 619. DOI: 10.1016/j.molcel.2006.08.003  0.76
2005 Weinberg RS, Ji X, Sutton M, Perrine S, Galperin Y, Li Q, Liebhaber SA, Stamatoyannopoulos G, Atweh GF. Butyrate increases the efficiency of translation of gamma-globin mRNA. Blood. 105: 1807-9. PMID 15479724 DOI: 10.1182/blood-2004-02-0454  0.76
2004 Cajiao I, Zhang A, Yoo EJ, Cooke NE, Liebhaber SA. Bystander gene activation by a locus control region. The Embo Journal. 23: 3854-63. PMID 15359275 DOI: 10.1038/sj.emboj.7600365  0.76
2004 Inácio A, Silva AL, Pinto J, Ji X, Morgado A, Almeida F, Faustino P, Lavinha J, Liebhaber SA, Romão L. Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay. The Journal of Biological Chemistry. 279: 32170-80. PMID 15161914 DOI: 10.1074/jbc.M405024200  0.76
2004 Su Y, Balice-Gordon RJ, Hess DM, Landsman DS, Minarcik J, Golden J, Hurwitz I, Liebhaber SA, Cooke NE. Neurobeachin is essential for neuromuscular synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3627-36. PMID 15071111 DOI: 10.1523/JNEUROSCI.4644-03.2004  0.76
2004 Kimura AP, Liebhaber SA, Cooke NE. Epigenetic modifications at the human growth hormone locus predict distinct roles for histone acetylation and methylation in placental gene activation. Molecular Endocrinology (Baltimore, Md.). 18: 1018-32. PMID 14715931 DOI: 10.1210/me.2003-0468  0.76
2004 Ho Y, Liebhaber SA, Cooke NE. Activation of the human GH gene cluster: roles for targeted chromatin modification. Trends in Endocrinology and Metabolism: Tem. 15: 40-5. PMID 14693425 DOI: 10.1016/j.tem.2003.11.004  0.76
2003 Chkheidze AN, Liebhaber SA. A novel set of nuclear localization signals determine distributions of the alphaCP RNA-binding proteins. Molecular and Cellular Biology. 23: 8405-15. PMID 14612387 DOI: 10.1128/MCB.23.23.8405-8415.2003  0.76
2003 Waggoner SA, Liebhaber SA. Identification of mRNAs associated with alphaCP2-containing RNP complexes. Molecular and Cellular Biology. 23: 7055-67. PMID 12972621 DOI: 10.1128/MCB.23.19.7055-7067.2003  0.76
2003 Waggoner SA, Liebhaber SA. Regulation of alpha-globin mRNA stability. Experimental Biology and Medicine (Maywood, N.J.). 228: 387-95. PMID 12671183 DOI: 10.1177/153537020322800409  0.76
2003 Kong J, Ji X, Liebhaber SA. The KH-domain protein alpha CP has a direct role in mRNA stabilization independent of its cognate binding site. Molecular and Cellular Biology. 23: 1125-34. PMID 12556474 DOI: 10.1128/MCB.23.4.1125-1134.2003  0.76
2003 Ji X, Kong J, Liebhaber SA. In vivo association of the stability control protein alphaCP with actively translating mRNAs. Molecular and Cellular Biology. 23: 899-907. PMID 12529395 DOI: 10.1128/MCB.23.3.899-907.2003  0.76
2003 Inácio A, Liebhaber SA. Pathways of mammalian messenger RNA degradation New Comprehensive Biochemistry. 38: 495-512. DOI: 10.1016/S0167-7306(03)38029-9  0.76
2002 Makeyev AV, Eastmond DL, Liebhaber SA. Targeting a KH-domain protein with RNA decoys. Rna (New York, N.Y.). 8: 1160-73. PMID 12358435  0.76
2002 Shewchuk BM, Liebhaber SA, Cooke NE. Specification of unique Pit-1 activity in the hGH locus control region. Proceedings of the National Academy of Sciences of the United States of America. 99: 11784-9. PMID 12189206 DOI: 10.1073/pnas.182418199  0.76
2002 Makeyev AV, Liebhaber SA. The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms. Rna (New York, N.Y.). 8: 265-78. PMID 12003487 DOI: 10.1017/S1355838202024627  0.76
2002 Ho Y, Elefant F, Cooke N, Liebhaber S. A defined locus control region determinant links chromatin domain acetylation with long-range gene activation. Molecular Cell. 9: 291-302. PMID 11864603 DOI: 10.1016/S1097-2765(02)00447-1  0.76
2002 White P, Liebhaber SA, Cooke NE. 129X1/SvJ mouse strain has a novel defect in inflammatory cell recruitment. Journal of Immunology (Baltimore, Md. : 1950). 168: 869-74. PMID 11777984  0.76
2001 Shewchuk BM, Cooke NE, Liebhaber SA. The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regions. Nucleic Acids Research. 29: 3356-61. PMID 11504873  0.76
2001 Thisted T, Lyakhov DL, Liebhaber SA. Optimized RNA Targets of Two Closely Related Triple KH Domain Proteins, Heterogeneous Nuclear Ribonucleoprotein K and αCP-2KL, Suggest Distinct Modes of RNA Recognition Journal of Biological Chemistry. 276: 17484-17496. PMID 11278705 DOI: 10.1074/jbc.M010594200  0.76
2001 Thompson KA, Richa J, Liebhaber SA, Storey BT. Dialysis addition of trehalose/glycerol cryoprotectant allows recovery of cryopreserved mouse spermatozoa with satisfactory fertilizing ability as assessed by yield of live young. Journal of Andrology. 22: 339-44. PMID 11229808  0.76
2000 Elefant F, Su Y, Liebhaber SA, Cooke NE. Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region. The Embo Journal. 19: 6814-22. PMID 11118216 DOI: 10.1093/emboj/19.24.6814  0.76
2000 Makeyev AV, Liebhaber SA. Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins Genomics. 67: 301-316. PMID 10936052 DOI: 10.1006/geno.2000.6244  0.76
2000 Elefant F, Cooke NE, Liebhaber SA. Targeted recruitment of histone acetyltransferase activity to a locus control region. The Journal of Biological Chemistry. 275: 13827-34. PMID 10788505 DOI: 10.1074/jbc.275.18.13827  0.76
2000 Su Y, Liebhaber SA, Cooke NE. The human growth hormone gene cluster locus control region supports position-independent pituitary- and placenta-specific expression in the transgenic mouse. The Journal of Biological Chemistry. 275: 7902-9. PMID 10713106 DOI: 10.1074/jbc.275.11.7902  0.76
1999 Shewchuk BM, Asa SL, Cooke NE, Liebhaber SA. Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation. The Journal of Biological Chemistry. 274: 35725-33. PMID 10585453 DOI: 10.1074/jbc.274.50.35725  0.76
1999 Makeyev AV, Chkheidze AN, Liebhaber SA. A set of highly conserved RNA-binding proteins, αCP-1 and αCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog Journal of Biological Chemistry. 274: 24849-24857. PMID 10455157 DOI: 10.1074/jbc.274.35.24849  0.76
1999 Song YH, Naumova AK, Liebhaber SA, Cooke NE. Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster. Genome Research. 9: 581-7. PMID 10400926  0.76
1999 Chkheidze AN, Lyakhov DL, Makeyev AV, Morales J, Kong J, Liebhaber SA. Assembly of the α-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein αCP Molecular and Cellular Biology. 19: 4572-4581. PMID 10373506  0.76
1999 Wang Z, Liebhaber SA. A 3'-flanking NF-κB site mediates developmental silencing of the human ζ-globin gene Embo Journal. 18: 2218-2228. PMID 10205175  0.76
1999 Safadi FF, Thornton P, Magiera H, Hollis BW, Gentile M, Haddad JG, Liebhaber SA, Cooke NE. Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein. The Journal of Clinical Investigation. 103: 239-51. PMID 9916136 DOI: 10.1172/JCI5244  0.76
1998 Russell JE, Liebhaber SA. Reversal of lethal α- and β-thalassemias in mice by expression of human embryonic globins Blood. 92: 3057-3063. PMID 9787139  0.76
1998 Song YH, Ray K, Liebhaber SA, Cooke NE. Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1alpha and 1beta. The Journal of Biological Chemistry. 273: 28408-18. PMID 9774468 DOI: 10.1074/jbc.273.43.28408  0.76
1998 Bennani-Baïti IM, Asa SL, Song D, Iratni R, Liebhaber SA, Cooke NE. DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression. Proceedings of the National Academy of Sciences of the United States of America. 95: 10655-60. PMID 9724759 DOI: 10.1073/pnas.95.18.10655  0.76
1998 Russell JE, Lee AE, Liebhaber SA. Full developmental silencing of the embryonic ζ-globin gene reflects instability of its mRNA Annals of the New York Academy of Sciences. 850: 386-390. PMID 9668563 DOI: 10.1111/j.1749-6632.1998.tb10499.x  0.76
1998 Liebhaber SA, Russell JE. Expression and developmental control of the human α-globin gene cluster Annals of the New York Academy of Sciences. 850: 54-63. PMID 9668527 DOI: 10.1111/j.1749-6632.1998.tb10462.x  0.76
1998 Russell JE, Morales J, Makeyev AV, Liebhaber SA. Sequence divergence in the 3' untranslated regions of human ζ- and α- globin mRNAs mediates a difference in their stabilities and contributes to efficient α-to-ζ gene developmental switching Molecular and Cellular Biology. 18: 2173-2183. PMID 9528789  0.76
1998 Bennani-Baïti IM, Cooke NE, Liebhaber SA. Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene. Genomics. 48: 258-64. PMID 9521881 DOI: 10.1006/geno.1997.5171  0.76
1997 Liebhaber SA. mRNA stability and the control of gene expression Nucleic Acids Symposium Series. 29-32. PMID 9478197  0.76
1997 Stefanovic B, Hellerbrand C, Holcik M, Briendl M, Liebhaber SA, Brenner DA. Posttranscriptional regulation of collagen α1(I) mRNA in hepatic stellate cells Molecular and Cellular Biology. 17: 5201-5209. PMID 9271398  0.76
1997 Russell JE, Morales J, Liebhaber SA. The role of mRNA stability in the control of globin gene expression Progress in Nucleic Acid Research and Molecular Biology. 57: 249-287. PMID 9175436  0.76
1997 Holcik M, Liebhaber SA. Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA- protein complexes sharing cis and trans components Proceedings of the National Academy of Sciences of the United States of America. 94: 2410-2414. PMID 9122208 DOI: 10.1073/pnas.94.6.2410  0.76
1997 Morales J, Russell JE, Liebhaber SA. Destabilization of human α-globin mRNA by translation anti-termination is controlled during erythroid differentiation and is paralleled by phased shortening of the poly(A) tail Journal of Biological Chemistry. 272: 6607-6613. PMID 9045690 DOI: 10.1074/jbc.272.10.6607  0.76
1997 Su Y, Liebhaber SA, Cooke NE. The human growth hormone locus control region supports pituitary- and placental-specific patterns of gene expression in transgenic mice Faseb Journal. 11.  0.76
1996 Wang X, Liebhaber SA. Complementary change in cis determinants and trans factors in the revolution of an mRNP stability complex Embo Journal. 15: 5040-5051. PMID 8890177  0.76
1996 Russell JE, Liebhaber SA. The stability of human β-globin mRNA is dependent on structural determinants positioned within its 3′ untranslated region Blood. 87: 5314-5323. PMID 8652847  0.76
1996 Liebhaber SA, Wang Z, Cash FE, Monks B, Russell JE. Developmental silencing of the embryonic ζ-globin gene: Concerted action of the promoter and the 3′-flanking region combined with stage-specific silencing by the transcribed segment Molecular and Cellular Biology. 16: 2637-2646. PMID 8649371  0.76
1996 Iratni R, Bennani-Baiti IM, Song D, Cookeand NE, Liebhaber SA. Detailed analysis of hypersensitive site III of the human growth hormone locus control region Faseb Journal. 10.  0.76
1995 Bennani-Baiti IM, Jones BK, Liebhaber SA, Cooke NE. Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17. Genomics. 29: 647-52. PMID 8575757 DOI: 10.1006/geno.1995.9954  0.76
1995 Jones BK, Monks BR, Liebhaber SA, Cooke NE. The human growth hormone gene is regulated by a multicomponent locus control region. Molecular and Cellular Biology. 15: 7010-21. PMID 8524268  0.76
1995 Wang X, Kiledjian M, Weiss IM, Liebhaber SA. Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human α-globin mRNA stability Molecular and Cellular Biology. 15: 1769-1777. PMID 7862166  0.76
1995 Weiss IM, Liebhaber SA. Erythroid cell-specific mRNA stability elements in the α2-globin 3' nontranslated region Molecular and Cellular Biology. 15: 2457-2465. PMID 7739530  0.76
1995 Kiledjian M, Wang X, Liebhaber SA. Identification of two KH domain proteins in the α-globin mRNP stability complex Embo Journal. 14: 4357-4364. PMID 7556077  0.76
1995 Pászty C, Mohandas N, Stevens ME, Loring JF, Liebhaber SA, Brion CM, Rubin EM. Lethal α–thalassaemia created by gene targeting in mice and its genetic rescue Nature Genetics. 11: 33-39. PMID 7550311 DOI: 10.1038/ng0995-33  0.76
1995 Cooke NE, Liebhaber SA. Molecular Biology of the Growth Hormone-Prolactin Gene System Vitamins and Hormones. 50: 385-459. DOI: 10.1016/S0083-6729(08)60659-7  0.76
1994 Misra-Press A, Cooke NE, Liebhaber SA. Complex alternative splicing partially inactivates the human chorionic somatomammotropin-like (hCS-L) gene. The Journal of Biological Chemistry. 269: 23220-9. PMID 8083227  0.76
1994 Weiss IM, Liebhaber SA. Erythroid cell-specific determinants of α-globin mRNA stability Molecular and Cellular Biology. 14: 8123-8132. PMID 7969150  0.76
1994 Estes PA, Urbanek M, Ray J, Liebhaber SA, Cooke NE. Alternative splice site selection in the human growth hormone gene transcript and synthesis of the 20 kDa isoform: role of higher order transcript structure. Acta Paediatrica (Oslo, Norway : 1992). Supplement. 399: 42-7; discussion 48. PMID 7949616  0.76
1994 Feuerstein R, Wang X, Song D, Cooke NE, Liebhaber SA. The LIM/double zinc-finger motif functions as a protein dimerization domain. Proceedings of the National Academy of Sciences of the United States of America. 91: 10655-9. PMID 7938009 DOI: 10.1073/pnas.91.22.10655  0.76
1993 Urbanek M, Russell JE, Cooke NE, Liebhaber SA. Functional characterization of the alternatively spliced, placental human growth hormone receptor. The Journal of Biological Chemistry. 268: 19025-32. PMID 8360189  0.76
1993 Russell JE, Liebhaber SA. Double-stranded RNA triggers generalized translational arrest in Xenopus oocytes Biochemical and Biophysical Research Communications. 194: 892-900. PMID 8343171 DOI: 10.1006/bbrc.1993.1905  0.76
1992 Tang W, Luo HY, Albitar M, Patterson M, Eng B, Waye JS, Liebhaber SA, Higgs DR, Chui DHK. Human embryonic ζ-globin chain expression in deletional α-thalassemias Blood. 80: 517-522. PMID 1627804  0.76
1992 Albitar M, Cash FE, Peschle C, Liebhaber SA. Developmental switch in the relative expression of the α1- and α2-globin genes in humans and in transgenic mice Blood. 79: 2471-2474. PMID 1571559  0.76
1992 Urbanek M, MacLeod JN, Cooke NE, Liebhaber SA. Expression of a human growth hormone (hGH) receptor isoform is predicted by tissue-specific alternative splicing of exon 3 of the hGH receptor gene transcript. Molecular Endocrinology (Baltimore, Md.). 6: 279-87. PMID 1569971 DOI: 10.1210/mend.6.2.1569971  0.76
1992 Albitar M, Care A, Peschle C, Liebhaber SA. Developmental switching of messenger RNA expression from the human α- globin cluster: Fetal/adult pattern of θ-globin gene expression Blood. 80: 1586-1591. PMID 1520882  0.76
1992 Liebhaber SA, Cash F, Eshleman SS. Translation inhibition by an mRNA coding region secondary structure is determined by its proximity to the AUG initiation codon Journal of Molecular Biology. 226: 609-621. PMID 1507219 DOI: 10.1016/0022-2836(92)90619-U  0.76
1992 Groebe DR, Busch MR, Moy Tsao TY, Luh FY, Tam MF, Chung AE, Gaskell M, Liebhaber SA, Ho C. High-level production of human α- and β-globins in insect cells Protein Expression and Purification. 3: 134-141. PMID 1422217 DOI: 10.1016/S1046-5928(05)80097-X  0.76
1992 Wang X, Ray K, Szpirer J, Levan G, Liebhaber SA, Cooke NE. Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism. Genomics. 14: 391-7. PMID 1385304 DOI: 10.1016/S0888-7543(05)80231-9  0.76
1992 MacLeod JN, Lee AK, Liebhaber SA, Cooke NE. Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster. The Journal of Biological Chemistry. 267: 14219-26. PMID 1378436  0.76
1992 Wang X, Lee G, Liebhaber SA, Cooke NE. Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc. The Journal of Biological Chemistry. 267: 9176-84. PMID 1374386  0.76
1991 MacLeod JN, Liebhaber SA, MacGillivray MH, Cooke NE. Identification of a splice-site mutation in the human growth hormone-variant gene. American Journal of Human Genetics. 48: 1168-74. PMID 2035535  0.76
1991 MacLeod JN, Worsley I, Ray J, Friesen HG, Liebhaber SA, Cooke NE. Human growth hormone-variant is a biologically active somatogen and lactogen. Endocrinology. 128: 1298-302. PMID 1999151 DOI: 10.1210/endo-128-3-1298  0.76
1991 Baumann G, Dávila N, Shaw MA, Ray J, Liebhaber SA, Cooke NE. Binding of human growth hormone (GH)-variant (placental GH) to GH-binding proteins in human plasma. The Journal of Clinical Endocrinology and Metabolism. 73: 1175-9. PMID 1955498 DOI: 10.1210/jcem-73-6-1175  0.76
1991 Nishikura K, Yoo C, Kim U, Murray JM, Estes PA, Cash FE, Liebhaber SA. Substrate specificity of the dsRNA unwinding/modifying activity. The Embo Journal. 10: 3523-32. PMID 1915306  0.76
1991 Goodman HM, Tai LR, Ray J, Cooke NE, Liebhaber SA. Human growth hormone variant produces insulin-like and lipolytic responses in rat adipose tissue. Endocrinology. 129: 1779-83. PMID 1915067 DOI: 10.1210/endo-129-4-1779  0.76
1991 Romao L, Osorio-Almeida L, Higgs DR, Lavinha J, Liebhaber SA. α-Thalassemia resulting from deletion of regulatory sequences far upstream of the α-globin structural genes Blood. 78: 1589-1595. PMID 1715793  0.76
1991 Albitar M, Katsumata M, Liebhaber SA. Human α-globin genes demonstrate autonomous developmental regulation in transgenic mice Molecular and Cellular Biology. 11: 3786-3794. PMID 1710771  0.76
1990 Ray J, Okamura H, Kelly PA, Cooke NE, Liebhaber SA. Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone. The Journal of Biological Chemistry. 265: 7939-44. PMID 2335510  0.76
1990 Weiss I, Cash FE, Coleman MB, Pressley A, Adams JG, Sanguansermsri T, Liebhaber SA, Steinberg MH. Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) Blood. 76: 2630-6. PMID 2265255  0.76
1990 Estes PA, Cooke NE, Liebhaber SA. A difference in the splicing patterns of the closely related normal and variant human growth hormone gene transcripts is determined by a minimal sequence divergence between two potential splice-acceptor sites. The Journal of Biological Chemistry. 265: 19863-70. PMID 2174055  0.76
1990 Ray J, Okamura H, Kelly PA, Liebhaber SA, Cooke NE. Alteration in the receptor binding specificity of human growth hormone by genomic exon exchange. Molecular Endocrinology (Baltimore, Md.). 4: 101-7. PMID 2157972 DOI: 10.1210/mend-4-1-101  0.76
1990 Liebhaber SA, Emery JG, Urbanek M, Wang XK, Cooke NE. Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif. Nucleic Acids Research. 18: 3871-9. PMID 2115670 DOI: 10.1093/nar/18.13.3871  0.76
1990 Liebhaber SA, Griese EU, Weiss I, Cash FE, Ayyub H, Higgs DR, Horst J. Inactivation of human α-globin gene expression by a de novo deletion located upstream of the α-globin gene cluster Proceedings of the National Academy of Sciences of the United States of America. 87: 9431-9435. PMID 1701260 DOI: 10.1073/pnas.87.23.9431  0.76
1989 Cash FE, Monplaisir N, Goossens M, Liebhaber SA. Locus assignment of two α-globin structural mutants from the Caribbean basin: α Fort de France (α(45Arg)) and α Spanish Town (α(27Val)) Blood. 74: 833-835. PMID 2752146  0.76
1989 Albitar M, Peschle C, Liebhaber SA. Theta, zeta, and epsilon globin messenger RNAs are expressed in adults Blood. 74: 629-637. PMID 2752137  0.76
1989 Ray J, Jones BK, Liebhaber SA, Cooke NE. Glycosylated human growth hormone variant. Endocrinology. 125: 566-8. PMID 2737165 DOI: 10.1210/endo-125-1-566  0.76
1989 Liebhaber SA, Urbanek M, Ray J, Tuan RS, Cooke NE. Characterization and histologic localization of human growth hormone-variant gene expression in the placenta. The Journal of Clinical Investigation. 83: 1985-91. PMID 2723069 DOI: 10.1172/JCI114108  0.76
1989 Liebhaber SA. α thalassemia Hemoglobin. 13: 685-731. PMID 2699473 DOI: 10.3109/03630268908998845  0.76
1988 Shakin-Eshleman SH, Liebhaber SA. Influence of duplexes 3′ to the mRNA initiation codon on the efficiency of monosome formation Biochemistry. 27: 3975-3982. PMID 3415968  0.76
1988 Cooke NE, Ray J, Watson MA, Estes PA, Kuo BA, Liebhaber SA. Human growth hormone gene and the highly homologous growth hormone variant gene display different splicing patterns. The Journal of Clinical Investigation. 82: 270-5. PMID 3392209 DOI: 10.1172/JCI113582  0.76
1988 Cooke NE, Ray J, Emery JG, Liebhaber SA. Two distinct species of human growth hormone-variant mRNA in the human placenta predict the expression of novel growth hormone proteins. The Journal of Biological Chemistry. 263: 9001-6. PMID 3379057  0.76
1988 Liebhaber SA, Cash FE, Cornfield DB. Evidence for posttranslational control of Hb C synthesis in an individual with Hb C trait and α-thalassemia Blood. 71: 502-504. PMID 3337909  0.76
1987 Moi P, Cash FE, Liebhaber SA, Cao A, Pirastu M. An initiation codon mutation (AUG → GUG) of the human α1-globin gene: Structural characterization and evidence for a mild thalassemic phenotype Journal of Clinical Investigation. 80: 1416-1421. PMID 3680504 DOI: 10.1172/JCI113220  0.76
1987 Liebhaber SA, Coleman MB, Adams JG, Cash FE, Steinberg MH. Molecular basis for nondeletion α-thalassemia in American blacks α2(116GAG→UAG) Journal of Clinical Investigation. 80: 154-159. PMID 3597771 DOI: 10.1172/JCI113041  0.76
1987 Shakin SH, Liebhaber SA. Opposite responses of rabbit and human globin mRNAs to translational inhibition by cap analogues Biochemistry. 26: 7188-7193. PMID 3427068  0.76
1986 Liebhaber SA, Cash FE, Ballas SK. Human α-globin gene expression. The dominant role of the α2-locus in mRNA and protein synthesis Journal of Biological Chemistry. 261: 15327-15333. PMID 3771577  0.76
1986 Shakin SH, Liebhaber SA. Translational profiles of alpha 1-, alpha 2-, and beta-globin messenger ribonucleic acids in human reticulocytes Journal of Clinical Investigation. 78: 1125-1129. PMID 3760187  0.76
1986 Shakin SH, Liebhaber SA. Destabilization of messenger RNA/complementary DNA duplexes by the elongating 80 S ribosome Journal of Biological Chemistry. 261: 16018-16025. PMID 3023338  0.76
1986 Liebhaber SA, Ray J, Cooke NE. Synthesis of growth hormone-prolactin chimeric proteins and processing mutants by the exchange and deletion of genomic exons. The Journal of Biological Chemistry. 261: 14301-6. PMID 3021735  0.76
1985 Liebhaber SA, Cash FE, Main DM. Compensatory increase in α1-globin gene expression in individuals heterozygous for the α-thalassemia-2 deletion Journal of Clinical Investigation. 76: 1057-1064. PMID 4044827 DOI: 10.1172/JCI112058  0.76
1985 Liebhaber SA, Cash FE. Locus assignment of α-globin structural mutations by hybrid-selected translation Journal of Clinical Investigation. 75: 64-70. PMID 2981252  0.76
1984 Liebhaber SA, Cash FE, Shakin SH. Translationally associated helix-destabilizing activity in rabbit reticulocyte lysate Journal of Biological Chemistry. 259: 15597-15602. PMID 6096379  0.76
1984 Liebhaber SA, Rappaport EF, Cash FE. Hemoglobin I mutation encoded at both α-globin loci on the same chromosome: Concerted evolution in the human genome Science. 226: 14491-451. DOI: 10.1126/science.6505702  0.76
1983 Liebhaber SA, Kan YW. α-Thalassemia caused by an unstable α-globin mutant Journal of Clinical Investigation. 71: 461-466. PMID 6826718 DOI: 10.1172/JCI110790  0.76
1983 Liebhaber SA, Begley KA. Structural and evolutionary analysis of the two chimpanzee α-globin mRNAs Nucleic Acids Research. 11: 8915-8929. PMID 6689503 DOI: 10.1093/nar/11.24.8915  0.76
1983 Liebhaber SA, Manno CS. Update on hemoglobinopathies Disease-a-Month. 29: 6-74. PMID 6347588 DOI: 10.1016/0011-5029(83)90029-9  0.76
1983 Anagnou NP, Ley TJ, Chesbro B, Wright G, Kitchens C, Liebhaber S, Nienhuis AW, Deisseroth AB. Acquired α-thalassemia in preleukemia is due to decreased expression of all four α-globin genes Proceedings of the National Academy of Sciences of the United States of America. 80: 6051-6055. PMID 6136971 DOI: 10.1073/pnas.80.19.6051  0.76
1982 Wagner GM, Liebhaber SA, Cutting HO, Embury SH. Hematologic improvement following splenectomy for hemoglobin-H disease Western Journal of Medicine. 137: 325-328. PMID 7179951  0.76
1982 Liebhaber SA, Kan YW. Different rates of mRNA translation balance the expression of the two human α-globin loci Journal of Biological Chemistry. 257: 11852-11855. PMID 7118914  0.76
1982 Goossens M, Lee KY, Liebhaber SA, Kan YW. Globin structural mutant α125Leu→Pro is a novel cause of α-thalassaemia Nature. 296: 864-865. PMID 7070526 DOI: 10.1038/296864a0  0.76
1982 Liebhaber SA, Kan YW. Molecular pathology of α-thalassemia Birth Defects: Original Article Series. 18: 35-44. PMID 6760927  0.76
1981 Liebhaber SA, Trecartin RF, Kan YW. Beta thalassemia in Sardinia in the result of a nonsense mutation Transactions of the Association of American Physicians. 94: 88-96. PMID 7344233  0.76
1981 Liebhaber SA, Goossens M, Kan YW. Homology and concerted evolution at the α1 and α2 loci of human α-globin Nature. 290: 26-29. PMID 7010180 DOI: 10.1038/290026a0  0.76
1981 Liebhaber SA, Wai Kan Y. Differentiation of the mRNA transcripts originating from the α1- and α2-globin loci in normals and α-thalassemics Journal of Clinical Investigation. 68: 439-446. PMID 6894931 DOI: 10.1172/JCI110273  0.76
1981 Trecartin RF, Liebhaber SA, Chang JC. β° Thalassemia in Sardinia is caused by a nonsense mutation Journal of Clinical Investigation. 68: 1012-1017. PMID 6457059 DOI: 10.1172/JCI110323  0.76
1981 Sameshima M, Liebhaber SA, Schlessinger D. Dual pathways for ribonucleic acid turnover in WI-38 but not in I-cell human diploid fibroblasts Molecular and Cellular Biology. 1: 75-81. PMID 6086007  0.76
1980 Wolf S, Sameshima M, Liebhaber SA, Schlessinger D. Regulation of ribosomal ribonucleic acid levels in growing, 3H-arrested, and crisis-phase WI-38 human diploid fibroblasts Biochemistry. 19: 3484-3490. PMID 7407055 DOI: 10.1021/bi00556a012  0.76
1980 Liebhaber SA, Goossens MJ, Kan YW. Cloning and complete nucleotide sequence of human 5'-α-globin gene Proceedings of the National Academy of Sciences of the United States of America. 77: 7054-7058. PMID 6452630 DOI: 10.1073/pnas.77.12.7054  0.76
1978 Liebhaber SA, Schlessinger D. Tritium-arrested human diploid fibroblasts maintain balanced RNA and protein metabolism Experimental Cell Research. 112: 353-359. PMID 631223 DOI: 10.1016/0014-4827(78)90218-5  0.76
1978 Liebhaber SA, Wolf S, Schlessinger D. Differences in rRNA metabolism of primary and SV40-transformed human fibroblasts Cell. 13: 121-127. PMID 202397 DOI: 10.1016/0092-8674(78)90143-5  0.76
1972 Barchilon J, Liebhaber SA, Gershon RK. Significance of cell interactions in production of graft versus host splenomegaly Yale Journal of Biology and Medicine. 45: 519-529. PMID 4404559  0.76
1972 Liebhaber SA, Barchilon J, Gershon RK. Bidirectional effects of interaction between parental thymocytes and F1 spleen cells in the production of graft vs host splenomegaly Journal of Immunology. 109: 238-243. PMID 4403057  0.76
1972 Gershon RK, Liebhaber SA. The response of T cells to histocompatibility-2 antigens. Dose-response kinetics Journal of Experimental Medicine. 136: 112-127. PMID 4402392 DOI: 10.1084/jem.136.1.112  0.76
1972 Gershon RK, Cohen P, Hencin R, Liebhaber SA. Suppressor T cells Journal of Immunology. 108: 586-590. PMID 4401006  0.76
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