Jeffrey N. Weiser - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Microbiology Biology, Pathology

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shen P, Lees JA, Bee GCW, Brown SP, Weiser JN. Pneumococcal quorum sensing drives an asymmetric owner-intruder competitive strategy during carriage via the competence regulon. Nature Microbiology. 4: 198-208. PMID 30546100 DOI: 10.1038/s41564-018-0314-4  0.52
2015 Siegel SJ, Weiser JN. Mechanisms of Bacterial Colonization of the Respiratory Tract. Annual Review of Microbiology. 69: 425-44. PMID 26488280 DOI: 10.1146/annurev-micro-091014-104209  0.84
2015 Hergott CB, Roche AM, Naidu NA, Mesaros C, Blair IA, Weiser JN. Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection. The Journal of Clinical Investigation. 125: 3878-90. PMID 26426079 DOI: 10.1172/JCI81888  0.84
2015 Siegel SJ, Tamashiro E, Weiser JN. Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking. Plos Pathogens. 11: e1005004. PMID 26107875 DOI: 10.1371/journal.ppat.1005004  0.84
2015 Lemon JK, Miller MR, Weiser JN. Sensing of interleukin-1 cytokines during Streptococcus pneumoniae colonization contributes to macrophage recruitment and bacterial clearance. Infection and Immunity. 83: 3204-12. PMID 26034210 DOI: 10.1128/IAI.00224-15  0.84
2015 Weiser JN, Roche AM, Hergott CB, LaRose MI, Connolly T, Jorgensen WL, Leng L, Bucala R, Das R. Macrophage Migration Inhibitory Factor Is Detrimental in Pneumococcal Pneumonia and a Target for Therapeutic Immunomodulation. The Journal of Infectious Diseases. PMID 25943202 DOI: 10.1093/infdis/jiv262  0.84
2015 Lemon JK, Weiser JN. Degradation products of the extracellular pathogen Streptococcus pneumoniae access the cytosol via its pore-forming toxin. Mbio. 6. PMID 25604786 DOI: 10.1128/mBio.02110-14  0.84
2015 Roche AM, Richard AL, Rahkola JT, Janoff EN, Weiser JN. Antibody blocks acquisition of bacterial colonization through agglutination. Mucosal Immunology. 8: 176-85. PMID 24962092 DOI: 10.1038/mi.2014.55  0.84
2014 Singh AK, Pluvinage B, Higgins MA, Dalia AB, Woodiga SA, Flynn M, Lloyd AR, Weiser JN, Stubbs KA, Boraston AB, King SJ. Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae β-galactosidase, BgaA. Plos Pathogens. 10: e1004364. PMID 25210925 DOI: 10.1371/journal.ppat.1004364  0.84
2014 Richard AL, Siegel SJ, Erikson J, Weiser JN. TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model. Plos Pathogens. 10: e1004339. PMID 25166617 DOI: 10.1371/journal.ppat.1004339  0.84
2014 Wolf AI, Strauman MC, Mozdzanowska K, Whittle JR, Williams KL, Sharpe AH, Weiser JN, Caton AJ, Hensley SE, Erikson J. Coinfection with Streptococcus pneumoniae modulates the B cell response to influenza virus. Journal of Virology. 88: 11995-2005. PMID 25100838 DOI: 10.1128/JVI.01833-14  0.84
2014 Langereis JD, de Jonge MI, Weiser JN. Binding of human factor H to outer membrane protein P5 of non-typeable Haemophilus influenzae contributes to complement resistance. Molecular Microbiology. 94: 89-106. PMID 25091181 DOI: 10.1111/mmi.12741  0.84
2014 Langereis JD, Weiser JN. Shielding of a lipooligosaccharide IgM epitope allows evasion of neutrophil-mediated killing of an invasive strain of nontypeable Haemophilus influenzae. Mbio. 5: e01478-14. PMID 25053788 DOI: 10.1128/mBio.01478-14  0.84
2014 Siegel SJ, Roche AM, Weiser JN. Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source. Cell Host & Microbe. 16: 55-67. PMID 25011108 DOI: 10.1016/j.chom.2014.06.005  0.84
2014 Wolf AI, Strauman MC, Mozdzanowska K, Williams KL, Osborne LC, Shen H, Liu Q, Garlick D, Artis D, Hensley SE, Caton AJ, Weiser JN, Erikson J. Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease. Virology. 462: 254-65. PMID 24999050 DOI: 10.1016/j.virol.2014.06.019  0.84
2014 Das R, LaRose MI, Hergott CB, Leng L, Bucala R, Weiser JN. Macrophage migration inhibitory factor promotes clearance of pneumococcal colonization. Journal of Immunology (Baltimore, Md. : 1950). 193: 764-72. PMID 24928996 DOI: 10.4049/jimmunol.1400133  0.84
2014 DeBardeleben HK, Lysenko ES, Dalia AB, Weiser JN. Tolerance of a phage element by Streptococcus pneumoniae leads to a fitness defect during colonization. Journal of Bacteriology. 196: 2670-80. PMID 24816604 DOI: 10.1128/JB.01556-14  0.84
2014 Deshmukh HS, Liu Y, Menkiti OR, Mei J, Dai N, O'Leary CE, Oliver PM, Kolls JK, Weiser JN, Worthen GS. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nature Medicine. 20: 524-30. PMID 24747744 DOI: 10.1038/nm.3542  0.84
2014 Janoff EN, Rubins JB, Fasching C, Charboneau D, Rahkola JT, Plaut AG, Weiser JN. Pneumococcal IgA1 protease subverts specific protection by human IgA1 Mucosal Immunology. 7: 249-256. PMID 23820749 DOI: 10.1038/mi.2013.41  0.84
2013 Jen FE, Warren MJ, Schulz BL, Power PM, Swords WE, Weiser JN, Apicella MA, Edwards JL, Jennings MP. Dual pili post-translational modifications synergize to mediate meningococcal adherence to platelet activating factor receptor on human airway cells. Plos Pathogens. 9: e1003377. PMID 23696740 DOI: 10.1371/journal.ppat.1003377  0.84
2013 Clark SE, Eichelberger KR, Weiser JN. Evasion of killing by human antibody and complement through multiple variations in the surface oligosaccharide of Haemophilus influenzae. Molecular Microbiology. 88: 603-18. PMID 23577840 DOI: 10.1111/mmi.12214  0.84
2013 Weiser JN. The battle with the host over microbial size. Current Opinion in Microbiology. 16: 59-62. PMID 23395472 DOI: 10.1016/j.mib.2013.01.001  0.84
2013 Clark SE, Weiser JN. Microbial modulation of host immunity with the small molecule phosphorylcholine. Infection and Immunity. 81: 392-401. PMID 23230294 DOI: 10.1128/IAI.01168-12  0.84
2013 Dorrington MG, Roche AM, Chauvin SE, Tu Z, Mossman KL, Weiser JN, Bowdish DM. MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx. Journal of Immunology (Baltimore, Md. : 1950). 190: 250-8. PMID 23197261 DOI: 10.4049/jimmunol.1202113  0.84
2012 Bachman MA, Lenio S, Schmidt L, Oyler JE, Weiser JN. Interaction of lipocalin 2, transferrin, and siderophores determines the replicative niche of Klebsiella pneumoniae during pneumonia. Mbio. 3. PMID 23169997 DOI: 10.1128/mBio.00224-11  0.84
2012 Mukerji R, Mirza S, Roche AM, Widener RW, Croney CM, Rhee DK, Weiser JN, Szalai AJ, Briles DE. Pneumococcal surface protein A inhibits complement deposition on the pneumococcal surface by competing with the binding of C-reactive protein to cell-surface phosphocholine. Journal of Immunology (Baltimore, Md. : 1950). 189: 5327-35. PMID 23105137 DOI: 10.4049/jimmunol.1201967  0.84
2012 Lijek RS, Luque SL, Liu Q, Parker D, Bae T, Weiser JN. Protection from the acquisition of Staphylococcus aureus nasal carriage by cross-reactive antibody to a pneumococcal dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 109: 13823-8. PMID 22869727 DOI: 10.1073/pnas.1208075109  0.84
2012 Rodriguez JL, Dalia AB, Weiser JN. Increased chain length promotes pneumococcal adherence and colonization. Infection and Immunity. 80: 3454-9. PMID 22825449 DOI: 10.1128/IAI.00587-12  0.84
2012 Lijek RS, Weiser JN. Co-infection subverts mucosal immunity in the upper respiratory tract. Current Opinion in Immunology. 24: 417-23. PMID 22658762 DOI: 10.1016/j.coi.2012.05.005  0.84
2012 Clark SE, Snow J, Li J, Zola TA, Weiser JN. Phosphorylcholine allows for evasion of bactericidal antibody by Haemophilus influenzae. Plos Pathogens. 8: e1002521. PMID 22396641 DOI: 10.1371/journal.ppat.1002521  0.84
2012 Weiser JN. Pneumococcus and bacterial pneumonia Schaechter's Mechanisms of Microbial Disease: Fifth Edition. 169-177.  0.84
2011 Dalia AB, Weiser JN. Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody. Cell Host & Microbe. 10: 486-96. PMID 22100164 DOI: 10.1016/j.chom.2011.09.009  0.84
2011 Pluvinage B, Higgins MA, Abbott DW, Robb C, Dalia AB, Deng L, Weiser JN, Parsons TB, Fairbanks AJ, Vocadlo DJ, Boraston AB. Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis. Structure (London, England : 1993). 19: 1603-14. PMID 22078560 DOI: 10.1016/j.str.2011.08.011  0.84
2011 Son MR, Shchepetov M, Adrian PV, Madhi SA, de Gouveia L, von Gottberg A, Klugman KP, Weiser JN, Dawid S. Conserved mutations in the pneumococcal bacteriocin transporter gene, blpA, result in a complex population consisting of producers and cheaters. Mbio. 2. PMID 21896678 DOI: 10.1128/mBio.00179-11  0.84
2011 Clarke TB, Weiser JN. Intracellular sensors of extracellular bacteria. Immunological Reviews. 243: 9-25. PMID 21884164 DOI: 10.1111/j.1600-065X.2011.01039.x  0.84
2011 Davis KM, Nakamura S, Weiser JN. Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice. The Journal of Clinical Investigation. 121: 3666-76. PMID 21841315 DOI: 10.1172/JCI57761  0.84
2011 Nakamura S, Davis KM, Weiser JN. Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice. The Journal of Clinical Investigation. 121: 3657-65. PMID 21841308 DOI: 10.1172/JCI57762  0.84
2011 Bachman MA, Oyler JE, Burns SH, Caza M, Lépine F, Dozois CM, Weiser JN. Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2. Infection and Immunity. 79: 3309-16. PMID 21576334 DOI: 10.1128/IAI.05114-11  0.84
2011 Clarke TB, Francella N, Huegel A, Weiser JN. Invasive bacterial pathogens exploit TLR-mediated downregulation of tight junction components to facilitate translocation across the epithelium. Cell Host & Microbe. 9: 404-14. PMID 21575911 DOI: 10.1016/j.chom.2011.04.012  0.84
2011 Nakamura S, Shchepetov M, Dalia AB, Clark SE, Murphy TF, Sethi S, Gilsdorf JR, Smith AL, Weiser JN. Molecular basis of increased serum resistance among pulmonary isolates of non-typeable Haemophilus influenzae. Plos Pathogens. 7: e1001247. PMID 21253576 DOI: 10.1371/journal.ppat.1001247  0.84
2011 Davis KM, Weiser JN. Modifications to the peptidoglycan backbone help bacteria to establish infection. Infection and Immunity. 79: 562-70. PMID 21041496 DOI: 10.1128/IAI.00651-10  0.84
2010 Lysenko ES, Lijek RS, Brown SP, Weiser JN. Within-host competition drives selection for the capsule virulence determinant of Streptococcus pneumoniae. Current Biology : Cb. 20: 1222-6. PMID 20619820 DOI: 10.1016/j.cub.2010.05.051  0.84
2010 Roche AM, Weiser JN. Identification of the targets of cross-reactive antibodies induced by Streptococcus pneumoniae colonization. Infection and Immunity. 78: 2231-9. PMID 20231407 DOI: 10.1128/IAI.01058-09  0.84
2010 Dalia AB, Standish AJ, Weiser JN. Three surface exoglycosidases from Streptococcus pneumoniae, NanA, BgaA, and StrH, promote resistance to opsonophagocytic killing by human neutrophils. Infection and Immunity. 78: 2108-16. PMID 20160017 DOI: 10.1128/IAI.01125-09  0.84
2010 Clarke TB, Davis KM, Lysenko ES, Zhou AY, Yu Y, Weiser JN. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nature Medicine. 16: 228-31. PMID 20081863 DOI: 10.1038/nm.2087  0.84
2010 Hyams C, Yuste J, Bax K, Camberlein E, Weiser JN, Brown JS. Streptococcus pneumoniae resistance to complement-mediated immunity is dependent on the capsular serotype. Infection and Immunity. 78: 716-25. PMID 19948838 DOI: 10.1128/IAI.01056-09  0.84
2010 Weiser JN. The pneumococcus: why a commensal misbehaves. Journal of Molecular Medicine (Berlin, Germany). 88: 97-102. PMID 19898768 DOI: 10.1007/s00109-009-0557-x  0.84
2009 Bachman MA, Miller VL, Weiser JN. Mucosal lipocalin 2 has pro-inflammatory and iron-sequestering effects in response to bacterial enterobactin. Plos Pathogens. 5: e1000622. PMID 19834550 DOI: 10.1371/journal.ppat.1000622  0.84
2009 Standish AJ, Weiser JN. Human neutrophils kill Streptococcus pneumoniae via serine proteases. Journal of Immunology (Baltimore, Md. : 1950). 183: 2602-9. PMID 19620298 DOI: 10.4049/jimmunol.0900688  0.84
2009 Zhang Z, Clarke TB, Weiser JN. Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice. The Journal of Clinical Investigation. 119: 1899-909. PMID 19509469 DOI: 10.1172/JCI36731  0.84
2009 Zola TA, Lysenko ES, Weiser JN. Natural antibody to conserved targets of Haemophilus influenzae limits colonization of the murine nasopharynx. Infection and Immunity. 77: 3458-65. PMID 19451240 DOI: 10.1128/IAI.01564-08  0.84
2009 Beisswenger C, Lysenko ES, Weiser JN. Early bacterial colonization induces toll-like receptor-dependent transforming growth factor beta signaling in the epithelium. Infection and Immunity. 77: 2212-20. PMID 19255194 DOI: 10.1128/IAI.01224-08  0.84
2009 Dawid S, Sebert ME, Weiser JN. Bacteriocin activity of Streptococcus pneumoniae is controlled by the serine protease HtrA via posttranscriptional regulation. Journal of Bacteriology. 191: 1509-18. PMID 19103930 DOI: 10.1128/JB.01213-08  0.84
2008 Davis KM, Akinbi HT, Standish AJ, Weiser JN. Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae. Plos Pathogens. 4: e1000241. PMID 19079576 DOI: 10.1371/journal.ppat.1000241  0.84
2008 Zola TA, Lysenko ES, Weiser JN. Mucosal clearance of capsule-expressing bacteria requires both TLR and nucleotide-binding oligomerization domain 1 signaling. Journal of Immunology (Baltimore, Md. : 1950). 181: 7909-16. PMID 19017981  0.84
2008 Matthias KA, Roche AM, Standish AJ, Shchepetov M, Weiser JN. Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae. Journal of Immunology (Baltimore, Md. : 1950). 180: 6246-54. PMID 18424747  0.84
2008 Kadioglu A, Weiser JN, Paton JC, Andrew PW. The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nature Reviews. Microbiology. 6: 288-301. PMID 18340341 DOI: 10.1038/nrmicro1871  0.84
2007 Lysenko ES, Clarke TB, Shchepetov M, Ratner AJ, Roper DI, Dowson CG, Weiser JN. Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing. Plos Pathogens. 3: e118. PMID 17722978 DOI: 10.1371/journal.ppat.0030118  0.84
2007 Gould CV, Sniegowski PD, Shchepetov M, Metlay JP, Weiser JN. Identifying mutator phenotypes among fluoroquinolone-resistant strains of Streptococcus pneumoniae using fluctuation analysis. Antimicrobial Agents and Chemotherapy. 51: 3225-9. PMID 17664329 DOI: 10.1128/AAC.00336-07  0.84
2007 Beisswenger C, Coyne CB, Shchepetov M, Weiser JN. Role of p38 MAP kinase and transforming growth factor-beta signaling in transepithelial migration of invasive bacterial pathogens. The Journal of Biological Chemistry. 282: 28700-8. PMID 17650505 DOI: 10.1074/jbc.M703576200  0.84
2007 Ratner AJ, Aguilar JL, Shchepetov M, Lysenko ES, Weiser JN. Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria. Cellular Microbiology. 9: 1343-51. PMID 17474907 DOI: 10.1111/j.1462-5822.2006.00878.x  0.84
2007 Nelson AL, Ratner AJ, Barasch J, Weiser JN. Interleukin-8 secretion in response to aferric enterobactin is potentiated by siderocalin. Infection and Immunity. 75: 3160-8. PMID 17420239 DOI: 10.1128/IAI.01719-06  0.84
2007 Weiser JN, Austrian R. Effect of pneumococcal polysaccharide vaccine on nonbacteremic pneumococcal pneumonia. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 44: 1139-40; author repl. PMID 17366469 DOI: 10.1086/513032  0.84
2007 Roche AM, King SJ, Weiser JN. Live attenuated Streptococcus pneumoniae strains induce serotype-independent mucosal and systemic protection in mice. Infection and Immunity. 75: 2469-75. PMID 17339359 DOI: 10.1128/IAI.01972-06  0.84
2007 Fasching CE, Grossman T, Corthésy B, Plaut AG, Weiser JN, Janoff EN. Impact of the molecular form of immunoglobulin A on functional activity in defense against Streptococcus pneumoniae. Infection and Immunity. 75: 1801-10. PMID 17261616 DOI: 10.1128/IAI.01758-06  0.84
2007 Nelson AL, Roche AM, Gould JM, Chim K, Ratner AJ, Weiser JN. Capsule enhances pneumococcal colonization by limiting mucus-mediated clearance. Infection and Immunity. 75: 83-90. PMID 17088346 DOI: 10.1128/IAI.01475-06  0.84
2007 Dawid S, Roche AM, Weiser JN. The blp bacteriocins of Streptococcus pneumoniae mediate intraspecies competition both in vitro and in vivo. Infection and Immunity. 75: 443-51. PMID 17074857 DOI: 10.1128/IAI.01775-05  0.84
2006 Bender MH, Weiser JN. The atypical amino-terminal LPNTG-containing domain of the pneumococcal human IgA1-specific protease is required for proper enzyme localization and function. Molecular Microbiology. 61: 526-43. PMID 16776657 DOI: 10.1111/j.1365-2958.2006.05256.x  0.84
2006 Ratner AJ, Hippe KR, Aguilar JL, Bender MH, Nelson AL, Weiser JN. Epithelial cells are sensitive detectors of bacterial pore-forming toxins. The Journal of Biological Chemistry. 281: 12994-8. PMID 16520379 DOI: 10.1074/jbc.M511431200  0.84
2006 King SJ, Hippe KR, Weiser JN. Deglycosylation of human glycoconjugates by the sequential activities of exoglycosidases expressed by Streptococcus pneumoniae. Molecular Microbiology. 59: 961-74. PMID 16420364 DOI: 10.1111/j.1365-2958.2005.04984.x  0.84
2005 van Rossum AM, Lysenko ES, Weiser JN. Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model. Infection and Immunity. 73: 7718-26. PMID 16239576 DOI: 10.1128/IAI.73.11.7718-7726.2005  0.84
2005 Lysenko ES, Ratner AJ, Nelson AL, Weiser JN. The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfaces. Plos Pathogens. 1: e1. PMID 16201010 DOI: 10.1371/journal.ppat.0010001  0.84
2005 Nelson AL, Barasch JM, Bunte RM, Weiser JN. Bacterial colonization of nasal mucosa induces expression of siderocalin, an iron-sequestering component of innate immunity. Cellular Microbiology. 7: 1404-17. PMID 16153241 DOI: 10.1111/j.1462-5822.2005.00566.x  0.84
2005 Sebert ME, Patel KP, Plotnick M, Weiser JN. Pneumococcal HtrA protease mediates inhibition of competence by the CiaRH two-component signaling system Journal of Bacteriology. 187: 3969-3979. PMID 15937159 DOI: 10.1128/JB.187.12.3969-3979.2005  0.84
2005 Ratner AJ, Lysenko ES, Paul MN, Weiser JN. Synergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfaces. Proceedings of the National Academy of Sciences of the United States of America. 102: 3429-34. PMID 15728393 DOI: 10.1073/pnas.0500599102  0.84
2004 King SJ, Hippe KR, Gould JM, Bae D, Peterson S, Cline RT, Fasching C, Janoff EN, Weiser JN. Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway. Molecular Microbiology. 54: 159-71. PMID 15458413 DOI: 10.1111/j.1365-2958.2004.04252.x  0.84
2004 McCool TL, Weiser JN. Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization. Infection and Immunity. 72: 5807-13. PMID 15385481 DOI: 10.1128/IAI.72.10.5807-5813.2004  0.84
2004 Goldenberg HB, McCool TL, Weiser JN. Cross-reactivity of human immunoglobulin G2 recognizing phosphorylcholine and evidence for protection against major bacterial pathogens of the human respiratory tract. The Journal of Infectious Diseases. 190: 1254-63. PMID 15346335 DOI: 10.1086/424517  0.84
2003 Pericone CD, Park S, Imlay JA, Weiser JN. Factors contributing to hydrogen peroxide resistance in Streptococcus pneumoniae include pyruvate oxidase (SpxB) and avoidance of the toxic effects of the fenton reaction. Journal of Bacteriology. 185: 6815-25. PMID 14617646 DOI: 10.1128/JB.185.23.6815-6825.2003  0.84
2003 Fan X, Pericone CD, Lysenko E, Goldfine H, Weiser JN. Multiple mechanisms for choline transport and utilization in Haemophilus influenzae. Molecular Microbiology. 50: 537-48. PMID 14617177 DOI: 10.1046/j.1365-2958.2003.03703.x  0.84
2003 McCool TL, Cate TR, Tuomanen EI, Adrian P, Mitchell TJ, Weiser JN. Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization. Infection and Immunity. 71: 5724-32. PMID 14500493  0.6
2003 Weiser JN, Bae D, Fasching C, Scamurra RW, Ratner AJ, Janoff EN. Antibody-enhanced pneumococcal adherence requires IgA1 protease. Proceedings of the National Academy of Sciences of the United States of America. 100: 4215-20. PMID 12642661 DOI: 10.1073/pnas.0637469100  0.84
2003 Hong RW, Shchepetov M, Weiser JN, Axelsen PH. Transcriptional profile of the Escherichia coli response to the antimicrobial insect peptide cecropin A. Antimicrobial Agents and Chemotherapy. 47: 1-6. PMID 12499161 DOI: 10.1128/AAC.47.1.1-6.2003  0.84
2003 Weiser JN, Tuomanen EI. Disease-Oriented Approach to the Discovery of Novel Vaccines The Vaccine Book. 139-147. DOI: 10.1016/B978-012107258-2/50012-3  0.84
2002 Shakhnovich EA, King SJ, Weiser JN. Neuraminidase expressed by Streptococcus pneumoniae desialylates the lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzae: a paradigm for interbacterial competition among pathogens of the human respiratory tract. Infection and Immunity. 70: 7161-4. PMID 12438402 DOI: 10.1128/IAI.70.12.7161-7164.2002  0.84
2002 Pericone CD, Bae D, Shchepetov M, McCool T, Weiser JN. Short-sequence tandem and nontandem DNA repeats and endogenous hydrogen peroxide production contribute to genetic instability of Streptococcus pneumoniae. Journal of Bacteriology. 184: 4392-9. PMID 12142409 DOI: 10.1128/JB.184.16.4392-4399.2002  0.84
2002 Gould JM, Weiser JN. The inhibitory effect of C-reactive protein on bacterial phosphorylcholine platelet-activating factor receptor-mediated adherence is blocked by surfactant. The Journal of Infectious Diseases. 186: 361-71. PMID 12134232 DOI: 10.1086/341658  0.84
2002 Sebert ME, Palmer LM, Rosenberg M, Weiser JN. Microarray-based identification of htrA, a Streptococcus pneumoniae gene that is regulated by the CiaRH two-component system and contributes to nasopharyngeal colonization Infection and Immunity. 70: 4059-4067. PMID 12117912 DOI: 10.1128/IAI.70.8.4059-4067.2002  0.84
2002 Moser C, Weiner DJ, Lysenko E, Bals R, Weiser JN, Wilson JM. beta-Defensin 1 contributes to pulmonary innate immunity in mice. Infection and Immunity. 70: 3068-72. PMID 12010999 DOI: 10.1128/IAI.70.6.3068-3072.2002  0.84
2002 McCool TL, Cate TR, Moy G, Weiser JN. The immune response to pneumococcal proteins during experimental human carriage. The Journal of Experimental Medicine. 195: 359-65. PMID 11828011 DOI: 10.1084/jem.20011576  0.84
2002 Wang X, Moser C, Louboutin JP, Lysenko ES, Weiner DJ, Weiser JN, Wilson JM. Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung. Journal of Immunology (Baltimore, Md. : 1950). 168: 810-5. PMID 11777976  0.84
2001 Fan X, Goldfine H, Lysenko E, Weiser JN. The transfer of choline from the host to the bacterial cell surface requires glpQ in Haemophilus influenzae Molecular Microbiology. 41: 1029-1036. PMID 11555284 DOI: 10.1046/j.1365-2958.2001.02571.x  0.84
2001 Weiser JN, Bae D, Epino H, Gordon SB, Kapoor M, Zenewicz LA, Shchepetov M. Changes in availability of oxygen accentuate differences in capsular polysaccharide expression by phenotypic variants and clinical isolates of Streptococcus pneumoniae Infection and Immunity. 69: 5430-5439. PMID 11500414 DOI: 10.1128/IAI.69.9.5430-5439.2001  0.84
2001 Swords WE, Ketterer MR, Shao J, Campbell CA, Weiser JN, Apicella MA. Binding of the non-typeable Haemophilus influenzae lipooligosaccharide to the PAF receptor initiates host cell signalling Cellular Microbiology. 3: 525-536. PMID 11488814 DOI: 10.1046/j.1462-5822.2001.00132.x  0.84
2001 Gould JM, Weiser JN. Expression of C-reactive protein in the human respiratory tract Infection and Immunity. 69: 1747-1754. PMID 11179352 DOI: 10.1128/IAI.69.3.1747-1754.2001  0.84
2001 Tong HH, Weiser JN, James MA, DeMaria TF. Effect of influenza A virus infection on nasopharyngeal colonization and otitis media induced by transparent or opaque phenotype variants of Streptococcus pneumoniae in the chinchilla model. Infection and Immunity. 69: 602-6. PMID 11119562 DOI: 10.1128/IAI.69.1.602-606.2001  0.84
2000 Howard MD, Cox AD, Weiser JN, Schurig GG, Inzana TJ. Antigenic diversity of Haemophilus somnus lipooligosaccharide: Phase-variable accessibility of the phosphorylcholine epitope Journal of Clinical Microbiology. 38: 4412-4419. PMID 11101573  0.84
2000 Weiser JN. The generation of diversity by Haemophilus influenzae Trends in Microbiology. 8: 433-435. PMID 11044669 DOI: 10.1016/S0966-842X(00)01839-4  0.84
2000 Swords WE, Buscher BA, Ver Steeg Ii K, Preston A, Nichols WA, Weiser JN, Gibson BW, Apicella MA. Non-typeable Haemophilus influenzae adhere to and invade human bronchial epithelial cells via an interaction of lipooligosaccharide with the PAF receptor. Molecular Microbiology. 37: 13-27. PMID 10931302 DOI: 10.1046/j.1365-2958.2000.01952.x  0.84
2000 Overweg K, Pericone CD, Verhoef GG, Weiser JN, Meiring HD, De Jong AP, De Groot R, Hermans PW. Differential protein expression in phenotypic variants of Streptococcus pneumoniae. Infection and Immunity. 68: 4604-10. PMID 10899862 DOI: 10.1128/IAI.68.8.4604-4610.2000  0.84
2000 Pericone CD, Overweg K, Hermans PW, Weiser JN. Inhibitory and bactericidal effects of hydrogen peroxide production by Streptococcus pneumoniae on other inhabitants of the upper respiratory tract. Infection and Immunity. 68: 3990-7. PMID 10858213 DOI: 10.1128/IAI.68.7.3990-3997.2000  0.84
2000 Schweda EKH, Brisson JR, Alvelius G, Martin A, Weiser JN, Hood DW, Moxon ER, Richards JC. Characterization of the phosphocholine-substituted oligosaccharide in lipopolysaccharides of type b Haemophilus influenzae European Journal of Biochemistry. 267: 3902-3913. PMID 10849010 DOI: 10.1046/j.1432-1327.2000.01426.x  0.84
2000 Erwin AL, Brewah YA, Couchenour DA, Barren PR, Burke SJ, Choi GH, Lathigra R, Hanson MS, Weiser JN. Role of lipopolysaccharide phase variation in susceptibility of Haemophilus influenzae to bactericidal immunoglobulin M antibodies in rabbit sera Infection and Immunity. 68: 2804-2807. PMID 10768976 DOI: 10.1128/IAI.68.5.2804-2807.2000  0.84
2000 Silvestro L, Weiser JN, Axelsen PH. Antibacterial and antimembrane activities of cecropin A in Escherichia coli Antimicrobial Agents and Chemotherapy. 44: 602-607. PMID 10681325 DOI: 10.1128/AAC.44.3.602-607.2000  0.84
2000 Lysenko ES, Gould J, Bals R, Wilson JM, Weiser JN. Bacterial phosphorylcholine decreases susceptibility to the antimicrobial peptide LL-37/hCAP18 expressed in the upper respiratory tract Infection and Immunity. 68: 1664-1671. PMID 10678986 DOI: 10.1128/IAI.68.3.1664-1671.2000  0.84
2000 Lysenko E, Richards JC, Cox AD, Stewart A, Martin A, Kapoor M, Weiser JN. The position of phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae affects binding and sensitivity to C-reactive protein-mediated killing Molecular Microbiology. 35: 234-245. PMID 10632893 DOI: 10.1046/j.1365-2958.2000.01707.x  0.84
1999 Prasadarao NV, Lysenko E, Wass CA, Kim KS, Weiser JN. Opacity-associated protein A contributes to the binding of Haemophilus influenzae to chang epithelial cells Infection and Immunity. 67: 4153-4160. PMID 10417187  0.84
1999 Weiser JN, Kapoor M. Effect of intrastrain variation in the amount of capsular polysaccharide on genetic transformation of Streptococcus pneumoniae: Implications for virulence studies of encapsulated strains Infection and Immunity. 67: 3690-3692. PMID 10377162  0.84
1999 Kim JO, Romero-Steiner S, Sørensen UB, Blom J, Carvalho M, Barnard S, Carlone G, Weiser JN. Relationship between cell surface carbohydrates and intrastrain variation on opsonophagocytosis of Streptococcus pneumoniae. Infection and Immunity. 67: 2327-33. PMID 10225891  0.84
1999 Weiser JN. Adaptation of respiratory tract pathogens to innate and acquired immunity Pediatric Pulmonology. 28: 126-127.  0.84
1998 Weiser JN, Pan N. Adaptation of Haemophilus influenzae to acquired and innate humoral immunity based on phase variation of lipopolysaccharide Molecular Microbiology. 30: 767-775. PMID 10094625 DOI: 10.1046/j.1365-2958.1998.01108.x  0.84
1998 Weiser JN, Goldberg JB, Pan N, Wilson L, Virji M. The phosphorylcholine epitope undergoes phase variation on a 43- kilodalton protein in Pseudomonas aeruginosa and on pili of Neisseria meningitidis and Neisseria gonorrhoeae Infection and Immunity. 66: 4263-4267. PMID 9712776  0.84
1998 Ring A, Weiser JN, Tuomanen EI. Pneumococcal trafficking across the blood-brain barrier molecular analysis of a novel bidirectional pathway Journal of Clinical Investigation. 102: 347-360. PMID 9664076  0.84
1998 Weiser JN. Phase variation in colony opacity by Streptococcus pneumoniae Microbial Drug Resistance. 4: 129-135. PMID 9651000  0.84
1998 Kim JO, Weiser JN. Association of intrastrain phase variation in quantity of capsular polysaccharide and teichoic acid with the virulence of Streptococcus pneumoniae Journal of Infectious Diseases. 177: 368-377. PMID 9466523  0.84
1998 Weiser JN, Pan N, McGowan KL, Musher D, Martin A, Richards J. Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killing mediated by C-reactive protein Journal of Experimental Medicine. 187: 631-640. PMID 9463413 DOI: 10.1084/jem.187.4.631  0.84
1997 Rosenow C, Ryan P, Weiser JN, Johnson S, Fontan P, Ortqvist A, Masure HR. Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae Molecular Microbiology. 25: 819-829. PMID 9364908  0.84
1997 Silvestro L, Gupta K, Weiser JN, Axelsen PH. The concentration-dependent membrane activity of cecropin A Biochemistry. 36: 11452-11460. PMID 9298965 DOI: 10.1021/bi9630826  0.84
1997 Weiser JN, Shchepetov M, Chong STH. Decoration of lipopolysaccharide with phosphorylcholine: A phase- variable characteristic of Haemophilus influenzae Infection and Immunity. 65: 943-950. PMID 9038301  0.84
1997 Kim JO, Shchepetov M, Weiser JN. Association of intrastrain phase variation in quantity of capsular polysaccharide and teichoic acid with the virulence of Streptococcus pneumonioe Clinical Infectious Diseases. 25: 427.  0.84
1996 Wani JH, Gilbert JV, Plaut AG, Weiser JN. Identification, cloning, and sequencing of the immunoglobulin A1 protease gene of Streptococcus pneumoniae Infection and Immunity. 64: 3967-3974. PMID 8926056  0.84
1996 Weiser JN, Markiewicz Z, Tuomanen EI, Wani JH. Relationship between phase variation in colony morphology, intrastrain variation in cell wall physiology, and nasopharyngeal colonization by Streptococcus pneumoniae Infection and Immunity. 64: 2240-2245. PMID 8675333  0.84
1996 Prasadarao NV, Wass CA, Weiser JN, Stins MF, Huang SHE, Kim KS. Outer membrane protein A of Escherichia coli contributes to invasion of brain microvascular endothelial cells Infection and Immunity. 64: 146-153. PMID 8557332  0.84
1995 Weiser JN, Chong STH, Greenberg D, Fong W. Identification and characterization of a cell envelope protein of Haemophilus influenzae contributing to phase variation in colony opacity and nasopharyngeal colonization Molecular Microbiology. 17: 555-564. PMID 8559074 DOI: 10.1111/j.1365-2958.1995.mmi_17030555.x  0.84
1995 Cundell DR, Weiser JN, Shen J, Young A, Tuomanen EI. Relationship between colonial morphology and adherence of Streptococcus pneumoniae Infection and Immunity. 63: 757-761. PMID 7868244  0.84
1995 Saluja SK, Weiser JN. The genetic basis of colony opacity in Streptococcus pneumoniae: Evidence for the effect of box elements on the frequency of phenotypic variation Molecular Microbiology. 16: 215-227. PMID 7565084 DOI: 10.1111/j.1365-2958.1995.tb02294.x  0.84
1994 Weiser JN, Austrian R, Sreenivasan PK, Masure HR. Phase variation in pneumococcal opacity: Relationship between colonial morphology and nasopharyngeal colonization Infection and Immunity. 62: 2582-2589. PMID 8188381  0.84
1994 Lee W, Austrian R, Weiser JN. Recurrent pneumococcal bacteremia in normal children Pediatric Infectious Disease Journal. 13: 231-233. PMID 8177634  0.84
1993 Schweda EKH, Hegedus OE, Borrelli S, Lindberg AA, Weiser JN, Maskell DJ, Richard Moxon E. Structural studies of the saccharide part of the cell envelope lipopolysaccharide from Haemophilus influenzae strain AH1-3 (lic3 +) Carbohydrate Research. 246: 319-330. PMID 8370043 DOI: 10.1016/0008-6215(93)84043-6  0.84
1993 Weiser JN. Relationship between Colony Morphology and the Life Cycle of Haemophilus influenzae: The Contribution of Lipopolysaccharide Phase Variation to Pathogenesis Journal of Infectious Diseases. 168: 672-680. PMID 8102630 DOI: 10.1093/infdis/168.3.672  0.84
1992 Weiser JN. The oligosaccharide of Haemophilus influenzae Microbial Pathogenesis. 13: 335-342. PMID 1297912 DOI: 10.1016/0882-4010(92)90077-2  0.84
1991 Weiser JN, Gotschlich EC. The role of outer membrane protein A in Escherichia coli K-1 pathogenesis Transactions of the Association of American Physicians. 104: 278-284. PMID 1845152  0.84
1991 Weiser JN, Gotschlich EC. Outer membrane protein A (OmpA) contributes to serum resistance and pathogenicity of Escherichia coli K-1 Infection and Immunity. 59: 2252-2258. PMID 1646768  0.84
1990 Weiser JN, Williams A, Moxon ER. Phase-variable lipopolysaccharide structures enhance the invasive capacity of Haemophilus influenzae Infection and Immunity. 58: 3455-3457. PMID 2401571  0.84
1990 Rubens CE, Wessels MR, Kuypers JM, Kasper DL, Weiser JN. Molecular analysis of two group B streptococcal virulence factors Seminars in Perinatology. 14: 22-29. PMID 2173147  0.84
1990 Virji M, Weiser JN, Lindberg AA, Moxon ER. Antigenic similarities in lipopolysaccharides of Haemophilus and Neisseria and expression of a digalactoside structure also present on human cells Microbial Pathogenesis. 9: 441-450. PMID 1711142 DOI: 10.1016/0882-4010(90)90062-U  0.84
1990 Weiser JN, Maskell DJ, Butler PD, Lindberg AA, Moxon ER. Characterization of repetitive sequences controlling phase variation of Haemophilus influenzae lipopolysaccharide. Journal of Bacteriology. 172: 3304-9. PMID 1693145  0.84
1989 Weiser JN, Love JM, Moxon ER. The molecular mechanism of phase variation of H. influenzae lipopolysaccharide Cell. 59: 657-665. PMID 2479481 DOI: 10.1016/0092-8674(89)90011-1  0.84
1989 Weiser JN, Lindberg AA, Manning EJ, Hansen EJ, Moxon ER. Identification of a chromosomal locus for expression of lipopolysaccharide epitopes in Haemophilus influenzae Infection and Immunity. 57: 3045-3052. PMID 2476397  0.84
1989 Moxon ER, Kroll JS, Weiser JN. Haemophilus influenzae gene expression and bacterial invasion Current Topics in Infectious Diseases and Clinical Microbiology. 2: 95-98.  0.84
1987 Weiser JN, Rubens CE. Transposon mutagenesis group B streptococcus beta-hemolysin biosynthesis Infection and Immunity. 55: 2314-2316. PMID 3040595  0.84
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