Thomas A. Jongens - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neuroscience Biology, Aging, Genetics

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, ... ... Jongens TA, et al. Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models. Frontiers in Behavioral Neuroscience. 10: 136. PMID 27445731 DOI: 10.3389/fnbeh.2016.00136  1
2016 Monyak RE, Emerson D, Schoenfeld BP, Zheng X, Chambers DB, Rosenfelt C, Langer S, Hinchey P, Choi CH, McDonald TV, Bolduc FV, Sehgal A, McBride SM, Jongens TA. Insulin signaling misregulation underlies circadian and cognitive deficits in a Drosophila fragile X model. Molecular Psychiatry. PMID 27090306 DOI: 10.1038/mp.2016.51  1
2015 Wu Y, Gause M, Xu D, Misulovin Z, Schaaf CA, Mosarla RC, Mannino E, Shannon M, Jones E, Shi M, Chen WF, Katz OL, Sehgal A, Jongens TA, Krantz ID, et al. Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior. Plos Genetics. 11: e1005655. PMID 26544867 DOI: 10.1371/journal.pgen.1005655  1
2015 Weisz ED, Monyak RE, Jongens TA. Deciphering discord: How Drosophila research has enhanced our understanding of the importance of FMRP in different spatial and temporal contexts. Experimental Neurology. PMID 26026973 DOI: 10.1016/j.expneurol.2015.05.015  1
2015 Gross C, Chang CW, Kelly SM, Bhattacharya A, McBride SM, Danielson SW, Jiang MQ, Chan CB, Ye K, Gibson JR, Klann E, Jongens TA, Moberg KH, Huber KM, Bassell GJ. Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome. Cell Reports. 11: 727-36. PMID 25921541 DOI: 10.1016/j.celrep.2015.03.060  1
2015 Choi CH, Schoenfeld BP, Weisz ED, Bell AJ, Chambers DB, Hinchey J, Choi RJ, Hinchey P, Kollaros M, Gertner MJ, Ferrick NJ, Terlizzi AM, Yohn N, Koenigsberg E, Liebelt DA, ... ... Jongens TA, et al. PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 396-408. PMID 25568131 DOI: 10.1523/JNEUROSCI.1356-12.2015  1
2014 Wolman MA, de Groh ED, McBride SM, Jongens TA, Granato M, Epstein JA. Modulation of cAMP and ras signaling pathways improves distinct behavioral deficits in a zebrafish model of neurofibromatosis type 1. Cell Reports. 8: 1265-70. PMID 25176649 DOI: 10.1016/j.celrep.2014.07.054  1
2013 McBride SM, Holloway SL, Jongens TA. Using Drosophila as a tool to identify pharmacological therapies for fragile X syndrome. Drug Discovery Today. Technologies. 10: e129-36. PMID 24050241 DOI: 10.1016/j.ddtec.2012.09.005  1
2013 Schoenfeld BP, Choi RJ, Choi CH, Terlizzi AM, Hinchey P, Kollaros M, Ferrick NJ, Koenigsberg E, Ferreiro D, Leibelt DA, Siegel SJ, Bell AJ, McDonald TV, Jongens TA, McBride SM. The Drosophila DmGluRA is required for social interaction and memory. Frontiers in Pharmacology. 4: 64. PMID 23720628 DOI: 10.3389/fphar.2013.00064  1
2012 Berkowitz KM, Sowash AR, Koenig LR, Urcuyo D, Khan F, Yang F, Wang PJ, Jongens TA, Kaestner KH. Disruption of CHTF18 causes defective meiotic recombination in male mice. Plos Genetics. 8: e1002996. PMID 23133398 DOI: 10.1371/journal.pgen.1002996  1
2012 McBride SM, Bell AJ, Jongens TA. Behavior in a Drosophila model of fragile X. Results and Problems in Cell Differentiation. 54: 83-117. PMID 22009349 DOI: 10.1007/978-3-642-21649-7_6  1
2011 Bhogal B, Jepson JE, Savva YA, Pepper AS, Reenan RA, Jongens TA. Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein. Nature Neuroscience. 14: 1517-24. PMID 22037499 DOI: 10.1038/nn.2950  1
2011 Beerman RW, Jongens TA. A non-canonical start codon in the Drosophila fragile X gene yields two functional isoforms. Neuroscience. 181: 48-66. PMID 21333716 DOI: 10.1016/j.neuroscience.2011.02.029  1
2011 Choi CH, Schoenfeld BP, Bell AJ, Hinchey P, Kollaros M, Gertner MJ, Woo NH, Tranfaglia MR, Bear MF, Zukin RS, McDonald TV, Jongens TA, McBride SM. Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment. Brain Research. 1380: 106-19. PMID 21078304 DOI: 10.1016/j.brainres.2010.11.032  1
2010 Bhogal B, Jongens TA. Fragile X syndrome and model organisms: identifying potential routes of therapeutic intervention. Disease Models & Mechanisms. 3: 693-700. PMID 20682752 DOI: 10.1242/dmm.002006  1
2010 McBride SM, Choi CH, Schoenfeld BP, Bell AJ, Liebelt DA, Ferreiro D, Choi RJ, Hinchey P, Kollaros M, Terlizzi AM, Ferrick NJ, Koenigsberg E, Rudominer RL, Sumida A, Chiorean S, ... ... Jongens TA, et al. Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9510-22. PMID 20631179 DOI: 10.1523/JNEUROSCI.1017-10.2010  1
2010 Kirino Y, Vourekas A, Kim N, de Lima Alves F, Rappsilber J, Klein PS, Jongens TA, Mourelatos Z. Arginine methylation of vasa protein is conserved across phyla. The Journal of Biological Chemistry. 285: 8148-54. PMID 20080973 DOI: 10.1074/jbc.M109.089821  1
2010 Choi CH, McBride SM, Schoenfeld BP, Liebelt DA, Ferreiro D, Ferrick NJ, Hinchey P, Kollaros M, Rudominer RL, Terlizzi AM, Koenigsberg E, Wang Y, Sumida A, Nguyen HT, Bell AJ, ... ... Jongens TA, et al. Age-dependent cognitive impairment in a Drosophila fragile X model and its pharmacological rescue. Biogerontology. 11: 347-62. PMID 20039205 DOI: 10.1007/s10522-009-9259-6  1
2010 Kirino Y, Vourekas A, Sayed N, de Lima Alves F, Thomson T, Lasko P, Rappsilber J, Jongens TA, Mourelatos Z. Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. Rna (New York, N.Y.). 16: 70-8. PMID 19926723 DOI: 10.1261/rna.1869710  1
2009 Pepper AS, Beerman RW, Bhogal B, Jongens TA. Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects. Plos One. 4: e7618. PMID 19888420 DOI: 10.1371/journal.pone.0007618  1
2009 Kirino Y, Kim N, de Planell-Saguer M, Khandros E, Chiorean S, Klein PS, Rigoutsos I, Jongens TA, Mourelatos Z. Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nature Cell Biology. 11: 652-8. PMID 19377467 DOI: 10.1038/ncb1872  1
2008 Berkowitz KM, Kaestner KH, Jongens TA. Germline expression of mammalian CTF18, an evolutionarily conserved protein required for germ cell proliferation in the fly and sister chromatid cohesion in yeast. Molecular Human Reproduction. 14: 143-50. PMID 18250106 DOI: 10.1093/molehr/gan005  1
2005 McBride SM, Choi CH, Wang Y, Liebelt D, Braunstein E, Ferreiro D, Sehgal A, Siwicki KK, Dockendorff TC, Nguyen HT, McDonald TV, Jongens TA. Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome. Neuron. 45: 753-64. PMID 15748850 DOI: 10.1016/j.neuron.2005.01.038  1
2005 Costa A, Wang Y, Dockendorff TC, Erdjument-Bromage H, Tempst P, Schedl P, Jongens TA. The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway. Developmental Cell. 8: 331-42. PMID 15737929 DOI: 10.1016/j.devcel.2005.01.011  1
2005 Zarnescu DC, Jin P, Betschinger J, Nakamoto M, Wang Y, Dockendorff TC, Feng Y, Jongens TA, Sisson JC, Knoblich JA, Warren ST, Moses K. Fragile X protein functions with lgl and the par complex in flies and mice. Developmental Cell. 8: 43-52. PMID 15621528 DOI: 10.1016/j.devcel.2004.10.020  1
2004 Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA, Nelson DL, Moses K, Warren ST. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nature Neuroscience. 7: 113-7. PMID 14703574 DOI: 10.1038/nn1174  1
2003 Leatherman JL, Jongens TA. Transcriptional silencing and translational control: key features of early germline development. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 25: 326-35. PMID 12655640 DOI: 10.1002/bies.10247  1
2002 Leatherman JL, Levin L, Boero J, Jongens TA. germ cell-less acts to repress transcription during the establishment of the Drosophila germ cell lineage. Current Biology : Cb. 12: 1681-5. PMID 12361572 DOI: 10.1016/S0960-9822(02)01182-X  1
2002 Dockendorff TC, Su HS, McBride SM, Yang Z, Choi CH, Siwicki KK, Sehgal A, Jongens TA. Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest. Neuron. 34: 973-84. PMID 12086644 DOI: 10.1016/S0896-6273(02)00724-9  1
2001 Jaffe AB, Jongens TA. Structure-specific abnormalities associated with mutations in a DNA replication accessory factor in Drosophila. Developmental Biology. 230: 161-76. PMID 11161570 DOI: 10.1006/dbio.2000.0117  1
2000 Wan L, Dockendorff TC, Jongens TA, Dreyfuss G. Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Molecular and Cellular Biology. 20: 8536-47. PMID 11046149 DOI: 10.1128/MCB.20.22.8536-8547.2000  1
2000 Dockendorff TC, Robertson SE, Faulkner DL, Jongens TA. Genetic characterization of the 44D-45B region of the Drosophila melanogaster genome based on an F2 lethal screen. Molecular & General Genetics : Mgg. 263: 137-43. PMID 10732682  1
2000 Leatherman JL, Kaestner KH, Jongens TA. Identification of a mouse germ cell-less homologue with conserved activity in Drosophila. Mechanisms of Development. 92: 145-53. PMID 10727854 DOI: 10.1016/S0925-4773(99)00335-4  1
1999 Dockendorff TC, Tang Z, Jongens TA. Cloning of karyopherin-alpha3 from Drosophila through its interaction with the nuclear localization sequence of germ cell-less protein. Biological Chemistry. 380: 1263-72. PMID 10614818 DOI: 10.1515/BC.1999.161  1
1999 Robertson SE, Dockendorff TC, Leatherman JL, Faulkner DL, Jongens TA. germ cell-less is required only during the establishment of the germ cell lineage of Drosophila and has activities which are dependent and independent of its localization to the nuclear envelope. Developmental Biology. 215: 288-97. PMID 10545238 DOI: 10.1006/dbio.1999.9453  1
1998 Faulkner DL, Dockendorff TC, Jongens TA. Clonal analysis of cmp44E, which encodes a conserved putative transmembrane protein, indicates a requirement for cell viability in Drosophila. Developmental Genetics. 23: 264-74. PMID 9883579 DOI: 10.1002/(SICI)1520-6408(1998)23:4<264::AID-DVG2>3.0.CO;2-6  1
1994 Jongens TA, Ackerman LD, Swedlow JR, Jan LY, Jan YN. Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila. Genes & Development. 8: 2123-36. PMID 7958883  1
1993 Siegel V, Jongens TA, Jan LY, Jan YN. pipsqueak, an early acting member of the posterior group of genes, affects vasa level and germ cell-somatic cell interaction in the developing egg chamber. Development (Cambridge, England). 119: 1187-202. PMID 8306882  1
1993 Theurkauf WE, Alberts BM, Jan YN, Jongens TA. A central role for microtubules in the differentiation of Drosophila oocytes. Development (Cambridge, England). 118: 1169-80. PMID 8269846  1
1992 Jongens TA, Hay B, Jan LY, Jan YN. The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila. Cell. 70: 569-84. PMID 1380406 DOI: 10.1016/0092-8674(92)90427-E  1
1988 Jongens TA, Fowler T, Shermoen AW, Beckendorf SK. Functional redundancy in the tissue-specific enhancer of the Drosophila Sgs-4 gene. The Embo Journal. 7: 2559-67. PMID 3142764  1
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