Douglas L. Black - Publications

Affiliations: 
Molecular Biology 0573 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Yeom KH, Mitchell S, Linares AJ, Zheng S, Lin CH, Wang XJ, Hoffmann A, Black DL. Polypyrimidine tract-binding protein blocks miRNA-124 biogenesis to enforce its neuronal-specific expression in the mouse. Proceedings of the National Academy of Sciences of the United States of America. PMID 30401736 DOI: 10.1073/pnas.1809609115  0.32
2018 Vuong CK, Wei W, Lee JA, Lin CH, Damianov A, de la Torre-Ubieta L, Halabi R, Otis KO, Martin KC, O'Dell TJ, Black DL. Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1. Neuron. 98: 127-141.e7. PMID 29621484 DOI: 10.1016/j.neuron.2018.03.008  0.48
2017 Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL. Correction: The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Elife. 6. PMID 28990924 DOI: 10.7554/eLife.31550  0.56
2017 Ying Y, Wang XJ, Vuong CK, Lin CH, Damianov A, Black DL. Splicing Activation by Rbfox Requires Self-Aggregation through Its Tyrosine-Rich Domain. Cell. 170: 312-323.e10. PMID 28708999 DOI: 10.1016/j.cell.2017.06.022  0.32
2017 Ke S, Pandya-Jones A, Saito Y, Fak JJ, Vågbø CB, Geula S, Hanna JH, Black DL, Darnell JE, Darnell RB. m(6)A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover. Genes & Development. 31: 990-1006. PMID 28637692 DOI: 10.1101/gad.301036.117  1
2016 Vuong JK, Lin CH, Zhang M, Chen L, Black DL, Zheng S. PTBP1 and PTBP2 Serve Both Specific and Redundant Functions in Neuronal Pre-mRNA Splicing. Cell Reports. 17: 2766-2775. PMID 27926877 DOI: 10.1016/j.celrep.2016.11.034  0.32
2016 Keppetipola NM, Yeom KH, Hernandez AL, Bui T, Sharma S, Black DL. Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2. Rna (New York, N.Y.). PMID 27288314 DOI: 10.1261/rna.057505.116  1
2016 Damianov A, Ying Y, Lin CH, Lee JA, Tran D, Vashisht AA, Bahrami-Samani E, Xing Y, Martin KC, Wohlschlegel JA, Black DL. Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR. Cell. 165: 606-619. PMID 27104978 DOI: 10.1016/j.cell.2016.03.040  1
2016 Vuong CK, Black DL, Zheng S. The neurogenetics of alternative splicing. Nature Reviews. Neuroscience. 17: 265-81. PMID 27094079 DOI: 10.1038/nrn.2016.27  1
2015 Linares AJ, Lin CH, Damianov A, Adams KL, Novitch BG, Black DL. The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation. Elife. 4. PMID 26705333 DOI: 10.7554/eLife.09268  1
2015 Lee JA, Damianov A, Lin CH, Fontes M, Parikshak NN, Anderson ES, Geschwind DH, Black DL, Martin KC. Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes. Neuron. PMID 26687839 DOI: 10.1016/j.neuron.2015.11.025  0.48
2014 Sharma S, Wongpalee SP, Vashisht A, Wohlschlegel JA, Black DL. Stem-loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly. Genes & Development. 28: 2518-31. PMID 25403181 DOI: 10.1101/gad.248625.114  1
2014 Han A, Stoilov P, Linares AJ, Zhou Y, Fu XD, Black DL. De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. Plos Computational Biology. 10: e1003442. PMID 24499931 DOI: 10.1371/journal.pcbi.1003442  1
2014 Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL. The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Elife. 3: e01201. PMID 24448406 DOI: 10.7554/eLife.01201  0.56
2014 Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL. The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation Elife. 2014. DOI: 10.7554/eLife.01201.001  1
2013 Lovci MT, Ghanem D, Marr H, Arnold J, Gee S, Parra M, Liang TY, Stark TJ, Gehman LT, Hoon S, Massirer KB, Pratt GA, Black DL, Gray JW, Conboy JG, et al. Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges. Nature Structural & Molecular Biology. 20: 1434-42. PMID 24213538 DOI: 10.1038/nsmb.2699  1
2013 Babic I, Anderson ES, Tanaka K, Guo D, Masui K, Li B, Zhu S, Gu Y, Villa GR, Akhavan D, Nathanson D, Gini B, Mareninov S, Li R, Camacho CE, ... ... Black DL, et al. EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer. Cell Metabolism. 17: 1000-8. PMID 23707073 DOI: 10.1016/j.cmet.2013.04.013  1
2013 Zheng S, Black DL. Alternative pre-mRNA splicing in neurons: growing up and extending its reach. Trends in Genetics : Tig. 29: 442-8. PMID 23648015 DOI: 10.1016/j.tig.2013.04.003  1
2013 Zheng S, Damoiseaux R, Chen L, Black DL. A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. Genome Research. 23: 998-1007. PMID 23636947 DOI: 10.1101/gr.147546.112  1
2013 Pandya-Jones A, Bhatt DM, Lin CH, Tong AJ, Smale ST, Black DL. Splicing kinetics and transcript release from the chromatin compartment limit the rate of Lipid A-induced gene expression. Rna (New York, N.Y.). 19: 811-27. PMID 23616639 DOI: 10.1261/rna.039081.113  1
2012 Bhatt DM, Pandya-Jones A, Tong AJ, Barozzi I, Lissner MM, Natoli G, Black DL, Smale ST. Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell. 150: 279-90. PMID 22817891 DOI: 10.1016/j.cell.2012.05.043  1
2012 Keppetipola N, Sharma S, Li Q, Black DL. Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2 Critical Reviews in Biochemistry and Molecular Biology. 47: 360-378. PMID 22655688 DOI: 10.3109/10409238.2012.691456  1
2012 Anderson ES, Lin CH, Xiao X, Stoilov P, Burge CB, Black DL. The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B. Rna (New York, N.Y.). 18: 1041-9. PMID 22456266 DOI: 10.1261/rna.032912.112  1
2012 Gehman LT, Meera P, Stoilov P, Shiue L, O'Brien JE, Meisler MH, Ares M, Otis TS, Black DL. The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Genes & Development. 26: 445-60. PMID 22357600 DOI: 10.1101/gad.182477.111  1
2012 Zheng S, Gray EE, Chawla G, Porse BT, O'Dell TJ, Black DL. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nature Neuroscience. 15: 381-8, S1. PMID 22246437 DOI: 10.1038/nn.3026  1
2011 Gehman LT, Stoilov P, Maguire J, Damianov A, Lin CH, Shiue L, Ares M, Mody I, Black DL. The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain. Nature Genetics. 43: 706-11. PMID 21623373 DOI: 10.1038/ng.841  1
2011 Tang ZZ, Sharma S, Zheng S, Chawla G, Nikolic J, Black DL. Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein. The Journal of Biological Chemistry. 286: 10007-16. PMID 21282112 DOI: 10.1074/jbc.M110.208116  1
2010 Black DL, Gorospe M. Tapas and RNA in Renaissance Spain. Rna Biology. 7: 130-2. PMID 20534974 DOI: 10.4161/rna.7.2.11060  1
2010 Damianov A, Black DL. Autoregulation of Fox protein expression to produce dominant negative splicing factors. Rna (New York, N.Y.). 16: 405-16. PMID 20042473 DOI: 10.1261/rna.1838210  1
2009 Xue Y, Zhou Y, Wu T, Zhu T, Ji X, Kwon YS, Zhang C, Yeo G, Black DL, Sun H, Fu XD, Zhang Y. Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Molecular Cell. 36: 996-1006. PMID 20064465 DOI: 10.1016/j.molcel.2009.12.003  1
2009 Lee JA, Tang ZZ, Black DL. An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons. Genes & Development. 23: 2284-93. PMID 19762510 DOI: 10.1101/gad.1837009  1
2009 Babic I, Sharma S, Black DL. A role for polypyrimidine tract binding protein in the establishment of focal adhesions. Molecular and Cellular Biology. 29: 5564-77. PMID 19667078 DOI: 10.1128/MCB.00590-09  1
2009 Pandya-Jones A, Black DL. Co-transcriptional splicing of constitutive and alternative exons. Rna (New York, N.Y.). 15: 1896-908. PMID 19656867 DOI: 10.1261/rna.1714509  1
2009 Tang ZZ, Zheng S, Nikolic J, Black DL. Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins. Molecular and Cellular Biology. 29: 4757-65. PMID 19564422 DOI: 10.1128/MCB.00608-09  1
2009 Chawla G, Lin CH, Han A, Shiue L, Ares M, Black DL. Sam68 regulates a set of alternatively spliced exons during neurogenesis. Molecular and Cellular Biology. 29: 201-13. PMID 18936165 DOI: 10.1128/MCB.01349-08  1
2008 Stoilov P, Lin CH, Damoiseaux R, Nikolic J, Black DL. A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators. Proceedings of the National Academy of Sciences of the United States of America. 105: 11218-23. PMID 18678901 DOI: 10.1073/pnas.0801661105  1
2008 Xing Y, Stoilov P, Kapur K, Han A, Jiang H, Shen S, Black DL, Wong WH. MADS: a new and improved method for analysis of differential alternative splicing by exon-tiling microarrays. Rna (New York, N.Y.). 14: 1470-9. PMID 18566192 DOI: 10.1261/rna.1070208  0.56
2008 Black DL, Zipursky SL. To cross or not to cross: alternatively spliced forms of the Robo3 receptor regulate discrete steps in axonal midline crossing. Neuron. 58: 297-8. PMID 18466738 DOI: 10.1016/j.neuron.2008.04.019  1
2008 Sharma S, Kohlstaedt LA, Damianov A, Rio DC, Black DL. Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome. Nature Structural & Molecular Biology. 15: 183-91. PMID 18193060 DOI: 10.1038/nsmb.1375  1
2007 Li Q, Lee JA, Black DL. Neuronal regulation of alternative pre-mRNA splicing. Nature Reviews. Neuroscience. 8: 819-31. PMID 17895907 DOI: 10.1038/nrn2237  1
2007 Boutz PL, Stoilov P, Li Q, Lin CH, Chawla G, Ostrow K, Shiue L, Ares M, Black DL. A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes & Development. 21: 1636-52. PMID 17606642 DOI: 10.1101/gad.1558107  1
2007 Lee JA, Xing Y, Nguyen D, Xie J, Lee CJ, Black DL. Depolarization and CaM kinase IV modulate NMDA receptor splicing through two essential RNA elements. Plos Biology. 5: e40. PMID 17298178 DOI: 10.1371/journal.pbio.0050040  1
2007 Boutz PL, Chawla G, Stoilov P, Black DL. MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes & Development. 21: 71-84. PMID 17210790 DOI: 10.1101/gad.1500707  1
2006 Sharma S, Black DL. Maps, codes, and sequence elements: can we predict the protein output from an alternatively spliced locus? Neuron. 52: 574-6. PMID 17114042 DOI: 10.1016/j.neuron.2006.11.005  1
2006 Black DL, Graveley BR. Splicing bioinformatics to biology. Genome Biology. 7: 317. PMID 16732900 DOI: 10.1186/gb-2006-7-5-317  1
2006 Auweter SD, Fasan R, Reymond L, Underwood JG, Black DL, Pitsch S, Allain FH. Molecular basis of RNA recognition by the human alternative splicing factor Fox-1. The Embo Journal. 25: 163-73. PMID 16362037 DOI: 10.1038/sj.emboj.7600918  1
2005 Xie J, Jan C, Stoilov P, Park J, Black DL. A consensus CaMK IV-responsive RNA sequence mediates regulation of alternative exons in neurons. Rna (New York, N.Y.). 11: 1825-34. PMID 16314456 DOI: 10.1261/rna.2171205  1
2005 Underwood JG, Boutz PL, Dougherty JD, Stoilov P, Black DL. Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals. Molecular and Cellular Biology. 25: 10005-16. PMID 16260614 DOI: 10.1128/MCB.25.22.10005-10016.2005  1
2005 Oberstrass FC, Auweter SD, Erat M, Hargous Y, Henning A, Wenter P, Reymond L, Amir-Ahmady B, Pitsch S, Black DL, Allain FH. Structure of PTB bound to RNA: specific binding and implications for splicing regulation. Science (New York, N.Y.). 309: 2054-7. PMID 16179478 DOI: 10.1126/science.1114066  0.32
2005 Sharma S, Falick AM, Black DL. Polypyrimidine tract binding protein blocks the 5' splice site-dependent assembly of U2AF and the prespliceosomal E complex. Molecular Cell. 19: 485-96. PMID 16109373 DOI: 10.1016/j.molcel.2005.07.014  1
2005 Amir-Ahmady B, Boutz PL, Markovtsov V, Phillips ML, Black DL. Exon repression by polypyrimidine tract binding protein. Rna (New York, N.Y.). 11: 699-716. PMID 15840818 DOI: 10.1261/rna.2250405  1
2005 Black DL. A simple answer for a splicing conundrum. Proceedings of the National Academy of Sciences of the United States of America. 102: 4927-8. PMID 15795368 DOI: 10.1073/pnas.0501414102  1
2004 Hall MP, Huang S, Black DL. Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA. Molecular Biology of the Cell. 15: 774-86. PMID 14657238 DOI: 10.1091/mbc.E03-09-0692  1
2003 Xie J, Lee JA, Kress TL, Mowry KL, Black DL. Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 100: 8776-81. PMID 12851456 DOI: 10.1073/pnas.1432696100  1
2003 Black DL. Mechanisms of alternative pre-messenger RNA splicing. Annual Review of Biochemistry. 72: 291-336. PMID 12626338 DOI: 10.1146/annurev.biochem.72.121801.161720  1
2003 Rooke N, Markovtsov V, Cagavi E, Black DL. Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1. Molecular and Cellular Biology. 23: 1874-84. PMID 12612063 DOI: 10.1128/MCB.23.6.1874-1884.2003  1
2003 Black DL, Grabowski PJ. Alternative pre-mRNA splicing and neuronal function. Progress in Molecular and Subcellular Biology. 31: 187-216. PMID 12494767  1
2001 Grabowski PJ, Black DL. Alternative RNA splicing in the nervous system. Progress in Neurobiology. 65: 289-308. PMID 11473790 DOI: 10.1016/S0301-0082(01)00007-7  1
2001 Xie J, Black DL. A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels Nature. 410: 936-939. PMID 11309619 DOI: 10.1038/35073593  1
2000 Black DL. Protein diversity from alternative splicing: A challenge for bioinformatics and post-genome biology Cell. 103: 367-370. PMID 11081623  1
2000 Chou MY, Underwood JG, Nikolic J, Luu MH, Black DL. Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing. Molecular Cell. 5: 949-57. PMID 10911989  1
1999 Modafferi EF, Black DL. Combinatorial control of a neuron-specific exon Rna. 5: 687-706. PMID 10334339 DOI: 10.1017/S1355838299990155  1
1999 Ring HZ, Vameghi-Meyers V, Nikolic JM, Min H, Black DL, Francke U. Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17. Genomics. 56: 350-2. PMID 10087204 DOI: 10.1006/geno.1998.5725  1
1999 Chou MY, Rooke N, Turck CW, Black DL. hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Molecular and Cellular Biology. 19: 69-77. PMID 9858532  1
1998 Black DL. Splicing in the inner ear: A familiar tune, but what are the instruments? Neuron. 20: 165-168. PMID 9491977 DOI: 10.1016/S0896-6273(00)80444-4  1
1997 Wei N, Lin CQ, Modafferi EF, Gomes WA, Black DL. A unique intronic splicing enhancer controls the inclusion of the agrin Y exon Rna. 3: 1275-1288. PMID 9409619  1
1997 Modafferi EF, Black DL. A complex intronic splicing enhancer from the c-src pre-mRNA activates inclusion of a heterologous exon Molecular and Cellular Biology. 17: 6537-6545. PMID 9343417  1
1997 Chan RC, Black DL. The polypyrimidine tract binding protein binds upstream of neural cell- specific c-src exert N1 to repress the splicing of the intron downstream Molecular and Cellular Biology. 17: 4667-4676. PMID 9234723  1
1997 Min H, Turck CW, Nikolic JM, Black DL. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer Genes and Development. 11: 1023-1036. PMID 9136930  1
1997 Chan RC, Black DL. Conserved intron elements repress splicing of a neuron-specific c-src exon in vitro Molecular and Cellular Biology. 17: 2970. PMID 9111368  1
1995 Min H, Chan RC, Black DL. The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event Genes and Development. 9: 2659-2671. PMID 7590243  1
1995 Black DL. Finding splice sites within a wilderness of RNA Rna (New York, N.Y.). 1: 763-771. PMID 7493322  1
1992 Black DL. Activation of c-src neuron-specific splicing by an unusual RNA element in vivo and in vitro Cell. 69: 795-807. PMID 1591778 DOI: 10.1016/0092-8674(92)90291-J  1
1991 Black DL. Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells? Genes and Development. 5: 389-402. PMID 2001841  1
1989 Black DL, Pinto AL. U5 small nuclear ribonucleoprotein: RNA structure analysis and ATP-dependent interaction with U4/U6 Molecular and Cellular Biology. 9: 3350-3359. PMID 2552294  1
1986 Black DL, Steitz JA. Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein. Cell. 46: 697-704. PMID 2427202 DOI: 10.1016/0092-8674(86)90345-4  1
1985 Black DL, Chabot B, Steitz JA. U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing. Cell. 42: 737-50. PMID 2996775 DOI: 10.1016/0092-8674(85)90270-3  1
1985 Chabot B, Black DL, LeMaster DM, Steitz JA. The 3' splice site of pre-messenger RNA is recognized by a small nuclear ribonucleoprotein. Science (New York, N.Y.). 230: 1344-9. PMID 2933810  1
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