Daniel T. Starczynowski, Ph.D. - Publications

Affiliations: 
2006 Boston University, Boston, MA, United States 
Area:
Molecular Biology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Shimizu R, Muto T, Aoyama K, Choi K, Takeuchi M, Koide S, Hasegawa N, Isshiki Y, Togasaki E, Kawajiri-Manako C, Nagao Y, Tsukamoto S, Sakai S, Takeda Y, Mimura N, ... ... Starczynowski DT, et al. Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia. Leukemia Research. 50: 85-94. PMID 27697661 DOI: 10.1016/j.leukres.2016.09.018  1
2015 Adams AK, Bolanos LC, Dexheimer PJ, Karns RA, Aronow BJ, Komurov K, Jegga AG, Casper KA, Patil YJ, Wilson KM, Starczynowski DT, Wells SI. IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival. Oncotarget. PMID 26527316 DOI: 10.18632/oncotarget.6028  1
2015 Varney ME, Niederkorn M, Konno H, Matsumura T, Gohda J, Yoshida N, Akiyama T, Christie S, Fang J, Miller D, Jerez A, Karsan A, Maciejewski JP, Meetei RA, Inoue J, ... Starczynowski DT, et al. Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling. The Journal of Experimental Medicine. 212: 1967-85. PMID 26458771 DOI: 10.1084/jem.20141898  1
2015 Gentner B, Pochert N, Rouhi A, Boccalatte F, Plati T, Berg T, Sun SM, Mah SM, Mirkovic-Hösle M, Ruschmann J, Muranyi A, Leierseder S, Argiropoulos B, Starczynowski DT, Karsan A, et al. MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia. Experimental Hematology. 43: 858-868.e7. PMID 26163797 DOI: 10.1016/j.exphem.2015.05.018  1
2015 Varney ME, Melgar K, Niederkorn M, Smith M, Barreyro L, Starczynowski DT. Deconstructing innate immune signaling in Myelodysplastic Syndromes. Experimental Hematology. PMID 26143580 DOI: 10.1016/j.exphem.2015.05.016  1
2015 Gañán-Gómez I, Wei Y, Starczynowski DT, Colla S, Yang H, Cabrero-Calvo M, Bohannan ZS, Verma A, Steidl U, Garcia-Manero G. Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes. Leukemia. 29: 1458-69. PMID 25761935 DOI: 10.1038/leu.2015.69  1
2015 Rhyasen GW, Starczynowski DT. IRAK signalling in cancer British Journal of Cancer. 112: 232-237. PMID 25290089 DOI: 10.1038/bjc.2014.513  1
2014 Chang KH, Sengupta A, Nayak RC, Duran A, Lee SJ, Pratt RG, Wellendorf AM, Hill SE, Watkins M, Gonzalez-Nieto D, Aronow BJ, Starczynowski DT, Civitelli R, Diaz-Meco MT, Moscat J, et al. p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche. Cell Reports. 9: 2084-97. PMID 25533346 DOI: 10.1016/j.celrep.2014.11.031  1
2014 Fang J, Barker B, Bolanos L, Liu X, Jerez A, Makishima H, Christie S, Chen X, Rao DS, Grimes HL, Komurov K, Weirauch MT, Cancelas JA, Maciejewski JP, Starczynowski DT. Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network. Cell Reports. 8: 1328-38. PMID 25199827 DOI: 10.1016/j.celrep.2014.07.062  1
2014 Starczynowski DT. Errant innate immune signaling in del(5q) MDS. Blood. 124: 669-71. PMID 25082861 DOI: 10.1182/blood-2014-06-581728  1
2014 Zhao JL, Starczynowski DT. Role of microRNA-146a in normal and malignant hematopoietic stem cell function. Frontiers in Genetics. 5: 219. PMID 25071842 DOI: 10.3389/fgene.2014.00219  1
2014 Beverly LJ, Starczynowski DT. IRAK1: oncotarget in MDS and AML. Oncotarget. 5: 1699-700. PMID 24880611 DOI: 10.18632/oncotarget.1880  1
2014 Rhyasen GW, Wunderlich M, Tohyama K, Garcia-Manero G, Mulloy JC, Starczynowski DT. An MDS xenograft model utilizing a patient-derived cell line Leukemia. 28: 1142-1145. PMID 24326684 DOI: 10.1038/leu.2013.372  1
2014 Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, et al. EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene. 33: 4464-73. PMID 24096489 DOI: 10.1038/onc.2013.396  1
2013 Rhyasen GW, Bolanos L, Starczynowski DT. Differential IRAK signaling in hematologic malignancies. Experimental Hematology. 41: 1005-7. PMID 24084080 DOI: 10.1016/j.exphem.2013.09.008  1
2013 Rhyasen GW, Bolanos L, Fang J, Jerez A, Wunderlich M, Rigolino C, Mathews L, Ferrer M, Southall N, Guha R, Keller J, Thomas C, Beverly LJ, Cortelezzi A, Oliva EN, ... ... Starczynowski DT, et al. Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome. Cancer Cell. 24: 90-104. PMID 23845443 DOI: 10.1016/j.ccr.2013.05.006  1
2013 Guo F, Zhang S, Grogg M, Cancelas JA, Varney ME, Starczynowski DT, Du W, Yang JQ, Liu W, Thomas G, Kozma S, Pang Q, Zheng Y. Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis. Haematologica. 98: 1353-8. PMID 23716557 DOI: 10.3324/haematol.2012.080424  1
2012 Vercauteren SM, Starczynowski DT, Sung S, McNeil K, Salski C, Jensen CL, Bruyere H, Lam WL, Karsan A. T cells of patients with myelodysplastic syndrome are frequently derived from the malignant clone. British Journal of Haematology. 156: 409-12. PMID 25289412 DOI: 10.1111/j.1365-2141.2011.08872.x  1
2012 Fang J, Rhyasen G, Bolanos L, Rasch C, Varney M, Wunderlich M, Goyama S, Jansen G, Cloos J, Rigolino C, Cortelezzi A, Mulloy JC, Oliva EN, Cuzzola M, Starczynowski DT. Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1. Blood. 120: 858-67. PMID 22685174 DOI: 10.1182/blood-2012-02-407999  1
2012 Fang J, Varney M, Starczynowski DT. Implication of microRNAs in the pathogenesis of MDS. Current Pharmaceutical Design. 18: 3170-9. PMID 22571695  1
2012 Rhyasen GW, Starczynowski DT. Deregulation of microRNAs in myelodysplastic syndrome Leukemia. 26: 13-22. PMID 21852786 DOI: 10.1038/leu.2011.221  1
2011 Starczynowski DT, Lockwood WW, Deléhouzée S, Chari R, Wegrzyn J, Fuller M, Tsao MS, Lam S, Gazdar AF, Lam WL, Karsan A. TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. The Journal of Clinical Investigation. 121: 4095-105. PMID 21911935 DOI: 10.1172/JCI58818  1
2011 Kuchenbauer F, Mah SM, Heuser M, McPherson A, Rüschmann J, Rouhi A, Berg T, Bullinger L, Argiropoulos B, Morin RD, Lai D, Starczynowski DT, Karsan A, Eaves CJ, Watahiki A, et al. Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells. Blood. 118: 3350-8. PMID 21628414 DOI: 10.1182/blood-2010-10-312454  1
2011 Starczynowski DT, Morin R, McPherson A, Lam J, Chari R, Wegrzyn J, Kuchenbauer F, Hirst M, Tohyama K, Humphries RK, Lam WL, Marra M, Karsan A. Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations. Blood. 117: 595-607. PMID 20962326 DOI: 10.1182/blood-2010-03-277012  1
2011 Starczynowski DT, Kuchenbauer F, Wegrzyn J, Rouhi A, Petriv O, Hansen CL, Humphries RK, Karsan A. MicroRNA-146a disrupts hematopoietic differentiation and survival. Experimental Hematology. 39: 167-178.e4. PMID 20933052 DOI: 10.1016/j.exphem.2010.09.011  1
2011 Starczynowski DT, Vercauteren S, Sung S, Brooks-Wilson A, Lam WL, Karsan A. Copy number alterations at polymorphic loci may be acquired somatically in patients with myelodysplastic syndromes. Leukemia Research. 35: 444-7. PMID 20801506 DOI: 10.1016/j.leukres.2010.08.003  1
2010 Vercauteren SM, Sung S, Starczynowski DT, Lam WL, Bruyere H, Horsman DE, Tsang P, Leitch H, Karsan A. Array comparative genomic hybridization of peripheral blood granulocytes of patients with myelodysplastic syndrome detects karyotypic abnormalities. American Journal of Clinical Pathology. 134: 119-26. PMID 20551276 DOI: 10.1309/AJCPH27ZIZEJLORF  1
2010 Starczynowski DT, Karsan A. Innate immune signaling in the myelodysplastic syndromes. Hematology/Oncology Clinics of North America. 24: 343-59. PMID 20359630 DOI: 10.1016/j.hoc.2010.02.008  1
2010 Starczynowski DT, Karsan A. Deregulation of innate immune signaling in myelodysplastic syndromes is associated with deletion of chromosome arm 5q. Cell Cycle (Georgetown, Tex.). 9: 855-6. PMID 20160505  1
2010 Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A, Hirst M, Hogge D, Marra M, Wells RA, Buckstein R, Lam W, Humphries RK, Karsan A. Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nature Medicine. 16: 49-58. PMID 19898489 DOI: 10.1038/nm.2054  1
2008 Starczynowski DT, Vercauteren S, Telenius A, Sung S, Tohyama K, Brooks-Wilson A, Spinelli JJ, Eaves CJ, Eaves AC, Horsman DE, Lam WL, Karsan A. High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival. Blood. 112: 3412-24. PMID 18663149 DOI: 10.1182/blood-2007-11-122028  1
2007 Starczynowski DT, Trautmann H, Pott C, Harder L, Arnold N, Africa JA, Leeman JR, Siebert R, Gilmore TD. Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity. Oncogene. 26: 2685-94. PMID 17072339 DOI: 10.1038/sj.onc.1210089  1
2005 Starczynowski DT, Reynolds JG, Gilmore TD. Mutations of tumor necrosis factor alpha-responsive serine residues within the C-terminal transactivation domain of human transcription factor REL enhance its in vitro transforming ability. Oncogene. 24: 7355-68. PMID 16027730 DOI: 10.1038/sj.onc.1208902  1
2004 Kalaitzidis D, Ok J, Sulak L, Starczynowski DT, Gilmore TD. Characterization of a human REL-estrogen receptor fusion protein with a reverse conditional transforming activity in chicken spleen cells. Oncogene. 23: 7580-7. PMID 15326488 DOI: 10.1038/sj.onc.1207912  1
2004 Gilmore TD, Starczynowski DT, Kalaitzidis D. RELevant gene amplification in B-cell lymphomas? Blood. 103: 3243-4; author reply. PMID 15070712 DOI: 10.1182/blood-2003-11-4019  1
2004 Gilmore TD, Kalaitzidis D, Liang MC, Starczynowski DT. The c-Rel transcription factor and B-cell proliferation: a deal with the devil. Oncogene. 23: 2275-86. PMID 14755244 DOI: 10.1038/sj.onc.1207410  1
2003 Starczynowski DT, Reynolds JG, Gilmore TD. Deletion of either C-terminal transactivation subdomain enhances the in vitro transforming activity of human transcription factor REL in chicken spleen cells. Oncogene. 22: 6928-36. PMID 14534540 DOI: 10.1038/sj.onc.1206801  1
2003 Leonida MD, Starczynowski DT, Waldman R, Aurian-Blajeni B. Polymeric FAD used as enzyme-friendly mediator in lactate detection. Analytical and Bioanalytical Chemistry. 376: 832-7. PMID 12811450 DOI: 10.1007/s00216-003-1991-1  1
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