Anne S. Hutchins, Ph.D. - Related publications

2003 University of Pennsylvania, Philadelphia, PA, United States 
Cell Biology, Genetics, Molecular Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Yang X, Bam M, Becker W, Nagarkatti PS, Nagarkatti M. Long Noncoding RNA AW112010 Promotes the Differentiation of Inflammatory T Cells by Suppressing IL-10 Expression through Histone Demethylation. Journal of Immunology (Baltimore, Md. : 1950). PMID 32690657 DOI: 10.4049/jimmunol.2000330   
2020 Shin MS, Kim D, Yim K, Park HJ, You S, Dong X, Koumpouras F, Shaw AC, Fan R, Krishnaswamy S, Kang I. IL-7 receptor alpha defines heterogeneity and signature of human effector memory CD8 T cells in high dimensional analysis. Cellular Immunology. 355: 104155. PMID 32619811 DOI: 10.1016/j.cellimm.2020.104155   
2020 Knochelmann HM, Dwyer CJ, Smith AS, Bowers JS, Wyatt MM, Nelson MH, Rangel Rivera GO, Horton JD, Krieg C, Armeson K, Lesinski GB, Rubinstein MP, Li Z, Paulos CM. IL-6 fuels durable memory for Th17 cell-mediated responses to tumors. Cancer Research. PMID 32561531 DOI: 10.1158/0008-5472.CAN-19-3685   
2020 Yan J, Hedl M, Abraham C. Myeloid Cell-Intrinsic IRF5 Promotes T Cell Responses through Multiple Distinct Checkpoints In Vivo, and Immune-Mediated Disease Risk Variants Modulate These Myeloid Cell Functions. Journal of Immunology (Baltimore, Md. : 1950). PMID 32690658 DOI: 10.4049/jimmunol.1900743   
2020 Inoue T, Aoyama-Ishikawa M, Uemura M, Yamashita H, Koga Y, Terashima M, Usami M, Kotani J, Hirata J. Interleukin-18 levels and mouse Leydig cell apoptosis during lipopolysaccharide-induced acute inflammatory conditions. Journal of Reproductive Immunology. 141: 103167. PMID 32629316 DOI: 10.1016/j.jri.2020.103167   
2020 De Biasi S, Meschiari M, Gibellini L, Bellinazzi C, Borella R, Fidanza L, Gozzi L, Iannone A, Lo Tartaro D, Mattioli M, Paolini A, Menozzi M, Milić J, Franceschi G, Fantini R, et al. Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia. Nature Communications. 11: 3434. PMID 32632085 DOI: 10.1038/s41467-020-17292-4   
2020 Kostrzewa-Nowak D, Nowak R. Differential Th Cell-Related Immune Responses in Young Physically Active Men after an Endurance Effort. Journal of Clinical Medicine. 9. PMID 32526904 DOI: 10.3390/jcm9061795   
2020 Aparicio-Domingo P, Cannelle H, Buechler MB, Nguyen S, Kallert SM, Favre S, Alouche N, Papazian N, Ludewig B, Cupedo T, Pinschewer DD, Turley SJ, Luther SA. Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T cell responses to acute and chronic viral infection. European Journal of Immunology. PMID 32700362 DOI: 10.1002/eji.201948413   
2020 Peng L, Zhong J, Xiao Y, Wang B, Li S, Deng Y, He D, Yuan J. Therapeutic effects of an anti-IL-6 antibody in fungal keratitis: Macrophage inhibition and T cell subset regulation. International Immunopharmacology. 85: 106649. PMID 32504999 DOI: 10.1016/j.intimp.2020.106649   
2020 Luo P, Deng S, Ye H, Yu X, Deng Q, Zhang Y, Jiang L, Li J, Yu Y, Han W. The IL-33/ST2 pathway suppresses murine colon cancer growth and metastasis by upregulating CD40 L signaling. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 127: 110232. PMID 32559854 DOI: 10.1016/j.biopha.2020.110232   
2020 Onishi K, Mochizuki J, Sato A, Goto A, Sashihara T. Total RNA and genomic DNA of Lactobacillus gasseri OLL2809 induce interleukin-12 production in the mouse macrophage cell line J774.1 via toll-like receptors 7 and 9. Bmc Microbiology. 20: 217. PMID 32689952 DOI: 10.1186/s12866-020-01900-w   
2020 Gao Y, Zeng Y, Xue W, Chen Y, Li Q, Bian Z, Tang L, Tang T, Chen C, Gao X, Guo W. Anti-IL-12/23 p40 antibody attenuates chronic graft-versus-host disease with lupus nephritis via inhibiting Tfh cell in mice. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 129: 110396. PMID 32580046 DOI: 10.1016/j.biopha.2020.110396   
2020 Kajiwara C, Kimura S, Tanaka Y, Akasaka Y, Ishii Y, Tateda K. Tissue Damage Caused by Impaired Phagocytosis of Dead Cells: A Previously Unrecognized Adverse Effect Contributing to the Pathogenesis of γδ T Cells in Pneumonia. Immunohorizons. 4: 402-414. PMID 32665299 DOI: 10.4049/immunohorizons.2000054   
2020 Li T, Zhou Y, Sun X, Bian Y, Wang K, Guo Q, Wang Q, Qiu F. Interleukin-2 maintains the survival of interleukin-17 gamma/delta T cells in inflammation and autoimmune diseases. International Immunopharmacology. 86: 106721. PMID 32615450 DOI: 10.1016/j.intimp.2020.106721   
2020 Hong H, Gao M, Wu Q, Yang P, Liu S, Li H, Burrows PD, Cua D, Chen JY, Hsu HC, Mountz JD. IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32554431 DOI: 10.4049/jimmunol.2000280   
2020 De Trez C, Stijlemans B, Bockstal V, Cnops J, Korf H, Van Snick J, Caljon G, Muraille E, Humphreys IR, Boon L, Van Ginderachter JA, Magez S. A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Infection. Frontiers in Immunology. 11: 1085. PMID 32655552 DOI: 10.3389/fimmu.2020.01085   
2020 Lu L, Wang P, Zou Y, Zha Z, Huang H, Guan M, Wu Y, Liu G. IL-1β Promotes Stemness of Tumor Cells by Activating Smad/ID1 Signaling Pathway. International Journal of Medical Sciences. 17: 1257-1268. PMID 32547321 DOI: 10.7150/ijms.44285   
2020 Rahman MA, Kanda Y, Ozawa M, Kawamura T, Takeuchi A, Katakai T. Transdermal entry of yeast components elicits transient B cell-associated responses in skin-draining lymph nodes. Cellular Immunology. 355: 104159. PMID 32711170 DOI: 10.1016/j.cellimm.2020.104159   
2020 Frangieh M, McHenry A, Phillips R, Ye C, Bernier A, Laffell L, Elyaman W, Bradshaw EM. IL-27: An endogenous constitutive repressor of human monocytes. Clinical Immunology (Orlando, Fla.). 108498. PMID 32531345 DOI: 10.1016/j.clim.2020.108498   
2020 Zhou Q, Zhang H, Wang Z, Zeng H, Liu Z, Huang Q, Lin Z, Qu Y, Xiong Y, Wang J, Chang Y, Bai Q, Xia Y, Wang Y, Liu L, et al. Poor clinical outcomes and immunoevasive contexture in interleukin-9 abundant muscle-invasive bladder cancer. International Journal of Cancer. PMID 32734613 DOI: 10.1002/ijc.33237   
2020 Giuffrida L, Sek K, Henderson MA, House IG, Lai J, Chen AXY, Todd KL, Petley EV, Mardiana S, Todorovski I, Gruber E, Kelly MJ, Solomon BJ, Vervoort SJ, Johnstone RW, et al. IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32735774 DOI: 10.1016/j.ymthe.2020.07.018   
2020 Rosenstock P, Bork K, Massa C, Selke P, Seliger B, Horstkorte R. Sialylation of Human Natural Killer (NK) Cells is Regulated by IL-2. Journal of Clinical Medicine. 9. PMID 32545211 DOI: 10.3390/jcm9061816   
2020 Qiao J, Fu YX. Cytokines that target immune killer cells against tumors. Cellular & Molecular Immunology. PMID 32523115 DOI: 10.1038/s41423-020-0481-0   
2020 Jackson ND, Everman JL, Chioccioli M, Feriani L, Goldfarbmuren KC, Sajuthi SP, Rios CL, Powell R, Armstrong M, Gomez J, Michel C, Eng C, Oh SS, Rodriguez-Santana J, Cicuta P, et al. Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma. Cell Reports. 32: 107872. PMID 32640237 DOI: 10.1016/j.celrep.2020.107872   
2020 Hegde M, Guruprasad KP, Ramachandra L, Satyamoorthy K, Joshi MB. Interleukin-6-mediated epigenetic control of the VEGFR2 gene induces disorganized angiogenesis in human breast tumors. The Journal of Biological Chemistry. PMID 32636303 DOI: 10.1074/jbc.RA120.012590   
2020 Xiao S, Bod L, Pochet N, Kota SB, Hu D, Madi A, Kilpatrick J, Shi J, Ho A, Zhang H, Sobel R, Weiner HL, Strom TB, Quintana FJ, Joller N, et al. Checkpoint Receptor TIGIT Expressed on Tim-1 B Cells Regulates Tissue Inflammation. Cell Reports. 32: 107892. PMID 32668241 DOI: 10.1016/j.celrep.2020.107892   
2020 Liao Y, Li X, Mou T, Zhou X, Li D, Wang L, Zhang Y, Dong X, Zheng H, Guo L, Liang Y, Jiang G, Fan S, Xu X, Xie Z, et al. Distinct infection process of SARS-CoV-2 in human bronchial epithelial cells line. Journal of Medical Virology. PMID 32558946 DOI: 10.1002/jmv.26200   
2020 Zogbi C, Oliveira NC, Levy D, Bydlowski SP, Bassaneze V, Neri EA, Krieger JE. Beneficial effects of IL-4 and IL-6 on rat neonatal target cardiac cells. Scientific Reports. 10: 12350. PMID 32704142 DOI: 10.1038/s41598-020-69413-0   
2020 Carpio VH, Aussenac F, Puebla-Clark L, Wilson KD, Villarino AV, Dent AL, Stephens R. T Helper Plasticity Is Orchestrated by STAT3, Bcl6, and Blimp-1 Balancing Pathology and Protection in Malaria. Iscience. 23: 101310. PMID 32634740 DOI: 10.1016/j.isci.2020.101310   
2020 Kang L, Tang X, Zhang J, Li M, Xu N, Qi W, Tan J, Lou X, Yu Z, Sun J, Wang Z, Dai H, Chen J, Lin G, Wu D, et al. Interleukin-6-knockdown of chimeric antigen receptor-modified T cells significantly reduces IL-6 release from monocytes. Experimental Hematology & Oncology. 9: 11. PMID 32523801 DOI: 10.1186/s40164-020-00166-2   
2020 Flores GA, Sandoval Pacheco CM, Sosa Ochoa WH, Gomes C, Zúniga C, Corbett C, Laurenti MW. Th17 lymphocytes in atypical cutaneous leishmaniasis caused by Leishmania (L.) infantum chagasi in Central America. Parasite Immunology. e12772. PMID 32603482 DOI: 10.1111/pim.12772   
2020 Liu H, Qiu F, Wang Y, Liang F, Liang J, Lin C, Liang J, Gong B, Chan S, De Zhang Z, Lai X, Hou S, Dai Z. A recombinant protein rLZ-8, originally extracted from Ganoderma lucidum, ameliorates OVA-induced lung inflammation by regulating Th17/Treg balance. Journal of Leukocyte Biology. PMID 32578901 DOI: 10.1002/JLB.5MA0420-453R   
2020 Shimba A, Ikuta K. Immune-enhancing effects of glucocorticoids in response to day-night cycles and stress. International Immunology. PMID 32710629 DOI: 10.1093/intimm/dxaa048   
2020 Danaii S, Ghorbani F, Ahmadi M, Abbaszadeh H, Koushaeian L, Soltani-Zangbar MS, Mehdizadeh A, Hojjat-Farsangi M, Kafil HS, Aghebati-Maleki L, Yousefi M. IL-10-producing B cells play important role in the pathogenesis of recurrent pregnancy loss. International Immunopharmacology. 87: 106806. PMID 32693358 DOI: 10.1016/j.intimp.2020.106806   
2020 Barros S, Ribeiro APD, Offenbacher S, Loewy ZG. Anti-Inflammatory Effects of Vitamin E in Response to . Microorganisms. 8. PMID 32466609 DOI: 10.3390/microorganisms8060804   
2020 Han J, Jiang Z, Wang C, Chen X, Li R, Sun N, Liu X, Wang H, Hong L, Zheng K, Yang J, Ikezoe T. Inhibition of Aurora-A promotes CD8+ T cell infiltration by mediating IL-10 production in cancer cells. Molecular Cancer Research : McR. PMID 32591441 DOI: 10.1158/1541-7786.MCR-19-1226   
2020 Pereira Neto TA, Gonçalves-Pereira MH, de Queiroz CP, Ramos MF, de Oliveira FFS, Oliveira-Prado R, do Nascimento VA, Abdalla LF, Santos JHA, Martins-Filho OA, Naveca FG, Teixeira-Carvalho A, Santiago HDC. Multifunctional T cell response in convalescent patients two years after ZIKV infection. Journal of Leukocyte Biology. PMID 32726884 DOI: 10.1002/JLB.4MA0520-708R   
2020 Tung SL, Fanelli G, Matthews RI, Bazoer J, Letizia M, Vizcay-Barrena G, Faruqu FN, Philippeos C, Hannen R, Al-Jamal KT, Lombardi G, Smyth LA. Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage. Frontiers in Cell and Developmental Biology. 8: 317. PMID 32509778 DOI: 10.3389/fcell.2020.00317   
2020 Hrabos D, Hnizdilova T, Tomala J, Uhlik J, Kovar M. IL-7/αIL-7 mAb M25 immunocomplexes expand CD8 T cells but paradoxically abrogate the antitumor activity of CTLA-4 and PD-1 blockage. Cytokine. 133: 155174. PMID 32599539 DOI: 10.1016/j.cyto.2020.155174   
2020 Zhang H, Yan X, Yang C, Zhan Q, Fu Y, Luo H, Luo H. Intrahepatic T helper 17 cells recruited by hepatitis B virus X antigen-activated hepatic stellate cells exacerbate the progression of chronic hepatitis B virus infection. Journal of Viral Hepatitis. PMID 32559002 DOI: 10.1111/jvh.13352   
2020 Çebi M, Durmus H, Aysal F, Özkan B, Gül GE, Çakar A, Hocaoglu M, Mercan M, Yentür SP, Tütüncü M, Yayla V, Akan O, Dogan Ö, Parman Y, Saruhan-Direskeneli G. CD4 T Cells of Myasthenia Gravis Patients Are Characterized by Increased IL-21, IL-4, and IL-17A Productions and Higher Presence of PD-1 and ICOS. Frontiers in Immunology. 11: 809. PMID 32508812 DOI: 10.3389/fimmu.2020.00809   
2020 Goll JB, Li S, Edwards JL, Bosinger SE, Jensen TL, Wang Y, Hooper WF, Gelber CE, Sanders KL, Anderson EJ, Rouphael N, Natrajan MS, Johnson RA, Sanz P, Hoft D, et al. Transcriptomic and Metabolic Responses to a Live-Attenuated Vaccine. Vaccines. 8. PMID 32722194 DOI: 10.3390/vaccines8030412   
2020 Waldmann TA, Dubois S, Miljkovic MD, Conlon KC. IL-15 in the Combination Immunotherapy of Cancer. Frontiers in Immunology. 11: 868. PMID 32508818 DOI: 10.3389/fimmu.2020.00868   
2020 Sato K, Yamamoto H, Nomura T, Kasamatsu J, Miyasaka T, Tanno D, Matsumoto I, Kagesawa T, Miyahara A, Zong T, Oniyama A, Kawamura K, Yokoyama R, Kitai Y, Ishizuka S, et al. Production of IL-17A at Innate Immune Phase Leads to Decreased Th1 Immune Response and Attenuated Host Defense against Infection with . Journal of Immunology (Baltimore, Md. : 1950). PMID 32561568 DOI: 10.4049/jimmunol.1901238   
2020 Lee GA, Liao NS. CD8CD122 T cell homeostasis is controlled by different levels of IL-15 trans-presentation. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. PMID 32616380 DOI: 10.1016/j.jmii.2020.06.005   
2020 Ghelani A, Bates D, Conner K, Wu MZ, Lu J, Hu YL, Li CM, Chaudhry A, Sohn SJ. Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using Engineered IL-2 Muteins. Frontiers in Immunology. 11: 1106. PMID 32582190 DOI: 10.3389/fimmu.2020.01106   
2020 Tang Z, Wang Y, Xing R, Zeng S, Di J, Xing F. Deltex-1 is indispensible for the IL-6 and TGF-β treatment-triggered differentiation of Th17 cells. Cellular Immunology. 356: 104176. PMID 32736174 DOI: 10.1016/j.cellimm.2020.104176   
2020 Robinson KF, Narasipura SD, Wallace J, Ritz EM, Al-Harthi L. β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes. Cell Communication and Signaling : Ccs. 18: 93. PMID 32546183 DOI: 10.1186/s12964-020-00565-2   
2020 Zhou T, Damsky W, Weizman OE, McGeary MK, Hartmann KP, Rosen CE, Fischer S, Jackson R, Flavell RA, Wang J, Sanmamed MF, Bosenberg MW, Ring AM. IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy. Nature. PMID 32581358 DOI: 10.1038/s41586-020-2422-6   
2020 Engel JA, Lee HJ, Williams CG, Kuns RD, Olver S, Lansink LI, Soon MS, Andersen SB, Powell JE, Svensson V, Teichmann SA, Hill GR, Varelias A, Koyama M, Haque A. Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD. Jci Insight. PMID 32484791 DOI: 10.1172/jci.insight.137990