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Bradley T. Scroggins, Ph.D. - Publications

Affiliations: 
2002 Oklahoma State University, Stillwater, OK, United States 
Area:
Biochemistry
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Sourbier C, Liao PJ, Ricketts CJ, Wei D, Yang Y, Baranes SM, Gibbs BK, Ohanjanian L, Spencer Krane L, Scroggins BT, Keith Killian J, Wei MH, Kijima T, Meltzer PS, Citrin DE, et al. Targeting loss of the Hippo signaling pathway in-deficient papillary kidney cancers. Oncotarget. 9: 10723-10733. PMID 29535838 DOI: 10.18632/Oncotarget.24112  0.341
2015 Chung EJ, McKay-Corkum G, Chung S, White A, Scroggins BT, Mitchell JB, Mulligan-Kehoe MJ, Citrin D. Truncated Plasminogen Activator Inhibitor-1 Protein Protects From Pulmonary Fibrosis Mediated by Irradiation in a Murine Model. International Journal of Radiation Oncology, Biology, Physics. PMID 26883561 DOI: 10.1016/J.Ijrobp.2015.11.044  0.346
2015 Prince TL, Kijima T, Tatokoro M, Lee S, Tsutsumi S, Yim K, Rivas C, Alarcon S, Schwartz H, Khamit-Kush K, Scroggins BT, Beebe K, Trepel JB, Neckers L. Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants. Plos One. 10: e0141786. PMID 26517842 DOI: 10.1371/Journal.Pone.0141786  0.533
2015 Sourbier C, Scroggins BT, Mannes PZ, Liao PJ, Siems K, Wolf D, Beutler JA, Linehan WM, Neckers L. Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent. Oncotarget. 6: 29963-74. PMID 26298773 DOI: 10.18632/Oncotarget.4676  0.327
2013 Beebe K, Mollapour M, Scroggins B, Prodromou C, Xu W, Tokita M, Taldone T, Pullen L, Zierer BK, Lee MJ, Trepel J, Buchner J, Bolon D, Chiosis G, Neckers L. Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitors. Oncotarget. 4: 1065-74. PMID 23867252 DOI: 10.18632/Oncotarget.1099  0.492
2013 Sourbier C, Scroggins BT, Ratnayake R, Prince TL, Lee S, Lee MJ, Nagy PL, Lee YH, Trepel JB, Beutler JA, Linehan WM, Neckers L. Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality. Cancer Cell. 23: 228-37. PMID 23352416 DOI: 10.1016/J.Ccr.2012.12.007  0.339
2012 Solier S, Kohn KW, Scroggins B, Xu W, Trepel J, Neckers L, Pommier Y. Heat shock protein 90α (HSP90α), a substrate and chaperone of DNA-PK necessary for the apoptotic response Proceedings of the National Academy of Sciences of the United States of America. 109: 12866-12872. PMID 22753480 DOI: 10.1073/Pnas.1203617109  0.345
2012 Xu W, Mollapour M, Prodromou C, Wang S, Scroggins BT, Palchick Z, Beebe K, Siderius M, Lee MJ, Couvillon A, Trepel JB, Miyata Y, Matts R, Neckers L. Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine. Molecular Cell. 47: 434-43. PMID 22727666 DOI: 10.1016/J.Molcel.2012.05.015  0.715
2012 Sun L, Prince T, Manjarrez JR, Scroggins BT, Matts RL. Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins. Biochimica Et Biophysica Acta. 1823: 1092-101. PMID 22504172 DOI: 10.1016/J.Bbamcr.2012.03.014  0.666
2010 Mollapour M, Tsutsumi S, Donnelly AC, Beebe K, Tokita MJ, Lee MJ, Lee S, Morra G, Bourboulia D, Scroggins BT, Colombo G, Blagg BS, Panaretou B, Stetler-Stevenson WG, Trepel JB, et al. Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function. Molecular Cell. 37: 333-43. PMID 20159553 DOI: 10.1016/J.Molcel.2010.01.005  0.585
2009 Tsutsumi S, Mollapour M, Graf C, Lee CT, Scroggins BT, Xu W, Haslerova L, Hessling M, Konstantinova AA, Trepel JB, Panaretou B, Buchner J, Mayer MP, Prodromou C, Neckers L. Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain. Nature Structural & Molecular Biology. 16: 1141-7. PMID 19838189 DOI: 10.1038/Nsmb.1682  0.432
2009 Scroggins BT, Neckers L. Just say NO: nitric oxide regulation of Hsp90. Embo Reports. 10: 1093-4. PMID 19763143 DOI: 10.1038/Embor.2009.212  0.516
2007 Scroggins BT, Neckers L. Post-translational modification of heat-shock protein 90: impact on chaperone function. Expert Opinion On Drug Discovery. 2: 1403-14. PMID 23484535 DOI: 10.1517/17460441.2.10.1403  0.533
2007 Scroggins BT, Robzyk K, Wang D, Marcu MG, Tsutsumi S, Beebe K, Cotter RJ, Felts S, Toft D, Karnitz L, Rosen N, Neckers L. An acetylation site in the middle domain of Hsp90 regulates chaperone function. Molecular Cell. 25: 151-9. PMID 17218278 DOI: 10.1016/J.Molcel.2006.12.008  0.471
2004 Eustace BK, Sakurai T, Stewart JK, Yimlamai D, Unger C, Zehetmeier C, Lain B, Torella C, Henning SW, Beste G, Scroggins BT, Neckers L, Ilag LL, Jay DG. Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness. Nature Cell Biology. 6: 507-14. PMID 15146192 DOI: 10.1038/Ncb1131  0.401
2003 Scroggins BT, Prince T, Shao J, Uma S, Huang W, Guo Y, Yun BG, Hedman K, Matts RL, Hartson SD. High affinity binding of Hsp90 is triggered by multiple discrete segments of its kinase clients. Biochemistry. 42: 12550-61. PMID 14580201 DOI: 10.1021/Bi035001T  0.732
2002 Thulasiraman V, Yun BG, Uma S, Gu Y, Scroggins BT, Matts RL. Differential inhibition of Hsc70 activities by two Hsc70-binding peptides. Biochemistry. 41: 3742-53. PMID 11888292 DOI: 10.1021/Bi012137N  0.647
2001 Shao J, Grammatikakis N, Scroggins BT, Uma S, Huang W, Chen JJ, Hartson SD, Matts RL. Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase. The Journal of Biological Chemistry. 276: 206-14. PMID 11036079 DOI: 10.1074/Jbc.M007583200  0.73
2000 Hartson SD, Irwin AD, Shao J, Scroggins BT, Volk L, Huang W, Matts RL. p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules. Biochemistry. 39: 7631-44. PMID 10858314 DOI: 10.1021/Bi000315R  0.733
2000 Yorgin PD, Hartson SD, Fellah AM, Scroggins BT, Huang W, Katsanis E, Couchman JM, Matts RL, Whitesell L. Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases. Journal of Immunology (Baltimore, Md. : 1950). 164: 2915-23. PMID 10706677 DOI: 10.4049/Jimmunol.164.6.2915  0.629
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