| Year |
Citation |
Score |
| 2021 |
Kakoki M, Ramanathan PV, Hagaman JR, Grant R, Wilder JC, Taylor JM, Charles Jennette J, Smithies O, Maeda-Smithies N. Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling. Communications Biology. 4: 775. PMID 34163008 DOI: 10.1038/s42003-021-02291-y |
0.276 |
|
| 2019 |
Kakoki M, Bahnson EM, Hagaman JR, Siletzky RM, Grant R, Kayashima Y, Li F, Lee EY, Sun MT, Taylor JM, Rice JC, Almeida MF, Bahr BA, Jennette JC, Smithies O, et al. Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production. Jci Insight. 4. PMID 31217360 DOI: 10.1172/Jci.Insight.127660 |
0.43 |
|
| 2019 |
Smithies O. How It All Began: A Personal History of Gel Electrophoresis. Methods in Molecular Biology (Clifton, N.J.). 1855: 1-21. PMID 30426402 DOI: 10.1007/978-1-4939-8793-1_1 |
0.255 |
|
| 2018 |
Govindapillai A, Hotchkiss A, Baguma-Nibasheka M, Rose RA, Miquerol L, Smithies O, Maeda N, Pasumarthi KBS. Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system. Scientific Reports. 8: 6939. PMID 29720615 DOI: 10.1038/S41598-018-25292-0 |
0.562 |
|
| 2018 |
Li F, Kakoki M, Smid M, Boggess K, Wilder J, Hiller S, Bounajim C, Parnell SE, Sulik KK, Smithies O, Maeda-Smithies N. Causative Effects of Genetically Determined High Maternal/Fetal Endothelin-1 on Preeclampsia-Like Conditions in Mice. Hypertension (Dallas, Tex. : 1979). PMID 29610266 DOI: 10.1161/Hypertensionaha.117.10849 |
0.409 |
|
| 2017 |
Bai X, Mangum K, Kakoki M, Smithies O, Mack CP, Taylor JM. GRAF3 serves as a blood volume-sensitive rheostat to control smooth muscle contractility and blood pressure. Small Gtpases. 0. PMID 29099324 DOI: 10.1080/21541248.2017.1375602 |
0.42 |
|
| 2017 |
Willett JD, Lawrence MG, Wilder JC, Smithies O. A tetraethylene glycol coat gives gold nanoparticles long in vivo half-lives with minimal increase in size. International Journal of Nanomedicine. 12: 2581-2592. PMID 28408825 DOI: 10.2147/Ijn.S121486 |
0.34 |
|
| 2017 |
Lawrence MG, Altenburg MK, Sanford R, Willett JD, Bleasdale B, Ballou B, Wilder J, Li F, Miner JH, Berg UB, Smithies O. Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules. Proceedings of the National Academy of Sciences of the United States of America. PMID 28246329 DOI: 10.1073/Pnas.1616457114 |
0.351 |
|
| 2017 |
Williams PA, Harder JM, Foxworth NE, Cochran KE, Philip VM, Porciatti V, Smithies O, John SW. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science (New York, N.Y.). 355: 756-760. PMID 28209901 DOI: 10.1126/Science.Aal0092 |
0.616 |
|
| 2016 |
Li F, Fushima T, Oyanagi G, Townley-Tilson HW, Sato E, Nakada H, Oe Y, Hagaman JR, Wilder J, Li M, Sekimoto A, Saigusa D, Sato H, Ito S, Jennette JC, ... ... Smithies O, et al. Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821757 DOI: 10.1073/Pnas.1614947113 |
0.534 |
|
| 2016 |
Chang AS, Grant R, Tomita H, Kim HS, Smithies O, Kakoki M. Prolactin alters blood pressure by modulating the activity of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791173 DOI: 10.1073/Pnas.1615051113 |
0.452 |
|
| 2016 |
Lawrence M, Testen A, Koklic T, Smithies O. A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions. Journal of Visualized Experiments : Jove. PMID 26890032 DOI: 10.3791/53388 |
0.327 |
|
| 2016 |
Hathaway CK, Chang AS, Grant R, Kim HS, Madden VJ, Bagnell CR, Jennette JC, Smithies O, Kakoki M. High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858454 DOI: 10.1073/Pnas.1600511113 |
0.421 |
|
| 2015 |
Chang AS, Hathaway CK, Smithies O, Kakoki M. Transforming growth factor β1 and diabetic nephropathy. American Journal of Physiology. Renal Physiology. ajprenal.00502.2015. PMID 26719364 DOI: 10.1152/Ajprenal.00502.2015 |
0.347 |
|
| 2015 |
Smithies O, Neill US. A conversation with Oliver Smithies. The Journal of Clinical Investigation. 125: 3997-8. PMID 26524588 DOI: 10.1172/JCI84087 |
0.194 |
|
| 2015 |
Smithies O, Gitschier J. The whole of a scientific career: an interview with Oliver Smithies. Plos Genetics. 11: e1005224. PMID 26020970 DOI: 10.1371/Journal.Pgen.1005224 |
0.177 |
|
| 2015 |
Hathaway CK, Gasim AM, Grant R, Chang AS, Kim HS, Madden VJ, Bagnell CR, Jennette JC, Smithies O, Kakoki M. Low TGFβ1 expression prevents and high expression exacerbates diabetic nephropathy in mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 5815-20. PMID 25902541 DOI: 10.1073/Pnas.1504777112 |
0.423 |
|
| 2015 |
Hathaway CK, Grant R, Hagaman JR, Hiller S, Li F, Xu L, Chang AS, Madden VJ, Bagnell CR, Rojas M, Kim HS, Wu B, Zhou B, Smithies O, Kakoki M. Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade. Proceedings of the National Academy of Sciences of the United States of America. 112: 5141-6. PMID 25848038 DOI: 10.1073/Pnas.1504557112 |
0.401 |
|
| 2015 |
Smithies O, Coffman T. A conversation with Oliver Smithies. Annual Review of Physiology. 77: 1-11. PMID 25668016 DOI: 10.1146/annurev-physiol-021014-071806 |
0.281 |
|
| 2015 |
Matsuki K, Hathaway CK, Chang AS, Smithies O, Kakoki M. Transforming growth factor beta1 and aldosterone. Current Opinion in Nephrology and Hypertension. 24: 139-44. PMID 25587902 DOI: 10.1097/Mnh.0000000000000100 |
0.377 |
|
| 2015 |
Smid M, Li F, Smithies O, Boggess K. 265: Endothelin-1 overexpression mimics preeclampsia in pregnant mice American Journal of Obstetrics and Gynecology. 212. DOI: 10.1016/J.Ajog.2014.10.311 |
0.432 |
|
| 2014 |
Matsuki K, Hathaway CK, Lawrence MG, Smithies O, Kakoki M. The role of transforming growth factor β1 in the regulation of blood pressure. Current Hypertension Reviews. 10: 223-38. PMID 25801626 DOI: 10.2174/157340211004150319123313 |
0.414 |
|
| 2014 |
Smithies O, Lawrence M, Testen A, Horne LP, Wilder J, Altenburg M, Bleasdale B, Maeda N, Koklic T. Stable oligomeric clusters of gold nanoparticles: preparation, size distribution, derivatization, and physical and biological properties. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 13394-404. PMID 25317930 DOI: 10.1021/La5032637 |
0.758 |
|
| 2014 |
Allred SC, Schreiner WJ, Smithies O. Colour blindness: still too many red-green figures. Nature. 510: 340. PMID 24943948 DOI: 10.1038/510340E |
0.301 |
|
| 2014 |
Wang C, Smithies O, Takahashi N. Inhibition of angiotensin II increases hypothalamic thyroid hormone and stimulates orexigenic NPY/AgRP neurons (LB437) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.Lb437 |
0.432 |
|
| 2014 |
Matsuki K, Hathaway CK, Lawrence MG, Smithies O, Kakoki M. The role of transforming growth factor β1 in the regulation of blood pressure Current Hypertension Reviews. 10: 223-238. |
0.23 |
|
| 2013 |
Bai X, Lenhart KC, Bird KE, Suen AA, Rojas M, Kakoki M, Li F, Smithies O, Mack CP, Taylor JM. The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension. Nature Communications. 4: 2910. PMID 24335996 DOI: 10.1038/Ncomms3910 |
0.44 |
|
| 2013 |
Kakoki M, Pochynyuk OM, Hathaway CM, Tomita H, Hagaman JR, Kim HS, Zaika OL, Mamenko M, Kayashima Y, Matsuki K, Hiller S, Li F, Xu L, Grant R, Bertorello AM, ... Smithies O, et al. Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1. Proceedings of the National Academy of Sciences of the United States of America. 110: 5600-5. PMID 23503843 DOI: 10.1073/Pnas.1302641110 |
0.45 |
|
| 2012 |
Vashistha H, Singhal PC, Malhotra A, Husain M, Mathieson P, Saleem MA, Kuriakose C, Seshan S, Wilk A, Delvalle L, Peruzzi F, Giorgio M, Pelicci PG, Smithies O, Kim HS, et al. Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney. American Journal of Physiology. Renal Physiology. 303: F1629-40. PMID 23019230 DOI: 10.1152/Ajprenal.00246.2012 |
0.437 |
|
| 2012 |
Pandya K, Kohro T, Mimura I, Kobayashi M, Wada Y, Kodama T, Smithies O. Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression. Gene Expression. 15: 183-98. PMID 22783727 DOI: 10.3727/105221612X13372578119698 |
0.464 |
|
| 2012 |
Smithies O. How it all began: a personal history of gel electrophoresis. Methods in Molecular Biology (Clifton, N.J.). 869: 1-21. PMID 22585472 DOI: 10.1007/978-1-61779-821-4_1 |
0.36 |
|
| 2012 |
Tomita H, Sanford RB, Smithies O, Kakoki M. The kallikrein-kinin system in diabetic nephropathy. Kidney International. 81: 733-44. PMID 22318421 DOI: 10.1038/Ki.2011.499 |
0.398 |
|
| 2012 |
Li F, Hagaman JR, Kim HS, Maeda N, Jennette JC, Faber JE, Karumanchi SA, Smithies O, Takahashi N. eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. Journal of the American Society of Nephrology : Jasn. 23: 652-60. PMID 22282588 DOI: 10.1681/Asn.2011040369 |
0.584 |
|
| 2012 |
Zajac B, Hakim ZS, Cameron MV, Smithies O, Taylor JM. Quantification of myocyte chemotaxis: a role for FAK in regulating directional motility. Methods in Molecular Biology (Clifton, N.J.). 843: 111-23. PMID 22222526 DOI: 10.1007/978-1-61779-523-7_11 |
0.375 |
|
| 2012 |
Kayashima Y, Smithies O, Kakoki M. The kallikrein-kinin system and oxidative stress. Current Opinion in Nephrology and Hypertension. 21: 92-6. PMID 22048723 DOI: 10.1097/Mnh.0B013E32834D54B1 |
0.352 |
|
| 2012 |
Reid LH, Smithies O. Gene Targeting and Electroporation Guide to Electroporation and Electrofusion. 209-225. DOI: 10.1016/B978-0-08-091727-6.50017-4 |
0.329 |
|
| 2012 |
Takahashi N, Li F, Wang CH, Mackman N, Maeda N, Smithies O, Jennette JC. Decreased eNOS and high fat diet in diabetic nephropathy Therapeutic Research. 33: 1206-1208. |
0.212 |
|
| 2011 |
Pandya K, Smithies O. β-MyHC and cardiac hypertrophy: size does matter. Circulation Research. 109: 609-10. PMID 21885833 DOI: 10.1161/Circresaha.111.252619 |
0.414 |
|
| 2011 |
Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N. Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite. Proceedings of the National Academy of Sciences of the United States of America. 108: 8779-84. PMID 21555558 DOI: 10.1073/Pnas.1106344108 |
0.559 |
|
| 2011 |
Wang CH, Li F, Hiller S, Kim HS, Maeda N, Smithies O, Takahashi N. A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Proceedings of the National Academy of Sciences of the United States of America. 108: 2070-5. PMID 21245338 DOI: 10.1073/Pnas.1018766108 |
0.555 |
|
| 2011 |
Hatada S, Walton W, Hatada T, Wofford A, Fox R, Liu N, Lill MC, Fair JH, Kirby SL, Smithies O. Therapeutic benefits in thalassemic mice transplanted with long-term-cultured bone marrow cells. Experimental Hematology. 39: 375-83, 383.e1-4. PMID 21184801 DOI: 10.1016/J.Exphem.2010.12.007 |
0.421 |
|
| 2011 |
Kakoki M, Smithies O. Kallikrein-kinin system in diabetes Kinins. 273-287. DOI: 10.1515/9783110252354 |
0.196 |
|
| 2011 |
Wang CH, Li F, Hiller S, Kim HS, Maeda N, Smithies O, Takahashi N. A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 5, (2070-2075) DOI:10.1073/pnas.1018766108) Proceedings of the National Academy of Sciences of the United States of America. 108: 3453. DOI: 10.1073/Pnas.1101346108 |
0.534 |
|
| 2010 |
Pandya K, Pulli B, Bultman S, Smithies O. Reversible epigenetic modifications of the two cardiac myosin heavy chain genes during changes in expression. Gene Expression. 15: 51-9. PMID 21526716 DOI: 10.3727/105221611X12973615737505 |
0.445 |
|
| 2010 |
Smithies O. Science brick by brick. Nature. 467: S6. PMID 20944621 DOI: 10.1038/467S6A |
0.396 |
|
| 2010 |
Konno T, Chen D, Wang L, Wakimoto H, Teekakirikul P, Nayor M, Kawana M, Eminaga S, Gorham JM, Pandya K, Smithies O, Naya FJ, Olson EN, Seidman JG, Seidman CE. Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 107: 18097-102. PMID 20923879 DOI: 10.1073/Pnas.1012826107 |
0.435 |
|
| 2010 |
Messadi E, Vincent MP, Griol-Charhbili V, Mandet C, Colucci J, Krege JH, Bruneval P, Bouby N, Smithies O, Alhenc-Gelas F, Richer C. Genetically determined angiotensin converting enzyme level and myocardial tolerance to ischemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4691-700. PMID 20667972 DOI: 10.1096/Fj.10-165902 |
0.377 |
|
| 2010 |
Wende AR, Soto J, Olsen CD, Pires KM, Schell JC, Larrieu-Lahargue F, Litwin SE, Kakoki M, Takahashi N, Smithies O, Abel ED. Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice. Endocrinology. 151: 3536-42. PMID 20501666 DOI: 10.1210/En.2010-0256 |
0.398 |
|
| 2010 |
Kakoki M, Sullivan KA, Backus C, Hayes JM, Oh SS, Hua K, Gasim AM, Tomita H, Grant R, Nossov SB, Kim HS, Jennette JC, Feldman EL, Smithies O. Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 10190-5. PMID 20479236 DOI: 10.1073/Pnas.1005144107 |
0.451 |
|
| 2010 |
Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. Journal of Immunology (Baltimore, Md. : 1950). 184: 4592-5. PMID 20410496 |
0.536 |
|
| 2010 |
Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in β2M, MHC class I proteins, and CD8+ T cells Journal of Immunology. 184: 1227-1230. DOI: 10.1126/science.2112266 |
0.528 |
|
| 2009 |
Tsai YS, Xu L, Smithies O, Maeda N. Genetic variations in peroxisome proliferator-activated receptor gamma expression affect blood pressure. Proceedings of the National Academy of Sciences of the United States of America. 106: 19084-9. PMID 19884495 DOI: 10.1073/Pnas.0909657106 |
0.596 |
|
| 2009 |
Scott NJ, Ellmers LJ, Lainchbury JG, Maeda N, Smithies O, Richards AM, Cameron VA. Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development. Biochimica Et Biophysica Acta. 1792: 1175-84. PMID 19782130 DOI: 10.1016/J.Bbadis.2009.09.009 |
0.563 |
|
| 2009 |
Brosius FC, Alpers CE, Bottinger EP, Breyer MD, Coffman TM, Gurley SB, Harris RC, Kakoki M, Kretzler M, Leiter EH, Levi M, McIndoe RA, Sharma K, Smithies O, Susztak K, et al. Mouse models of diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 20: 2503-12. PMID 19729434 DOI: 10.1681/Asn.2009070721 |
0.344 |
|
| 2009 |
Huby AC, Rastaldi MP, Caron K, Smithies O, Dussaule JC, Chatziantoniou C. Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin. Plos One. 4: e6721. PMID 19696925 DOI: 10.1371/Journal.Pone.0006721 |
0.414 |
|
| 2009 |
Pandya K, Porter K, Rockman HA, Smithies O. Decreased beta-adrenergic responsiveness following hypertrophy occurs only in cardiomyocytes that also re-express beta-myosin heavy chain. European Journal of Heart Failure. 11: 648-52. PMID 19553396 DOI: 10.1093/Eurjhf/Hfp073 |
0.408 |
|
| 2009 |
Epple-Farmer J, Debeb BG, Smithies O, Binas B. Gender-dependent survival of allogeneic trophoblast stem cells in liver. Cell Transplantation. 18: 769-76. PMID 19523327 DOI: 10.3727/096368909X470856 |
0.4 |
|
| 2009 |
Kakoki M, Smithies O. The kallikrein-kinin system in health and in diseases of the kidney. Kidney International. 75: 1019-30. PMID 19190676 DOI: 10.1038/Ki.2008.647 |
0.467 |
|
| 2009 |
Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R. RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 1205-10. PMID 19164558 DOI: 10.1073/Pnas.0812436106 |
0.694 |
|
| 2009 |
Long D, White K, Price K, Cas AD, Hayward A, Webster Z, Bilous R, Viberti G, Woolf A, Gnudi L, Kawakami T, Inagi R, Takano H, Sato S, Ingelfinger J, ... ... Smithies O, et al. Experimental pathology - 1 Ndt Plus. 2: 0. DOI: 10.1093/Ndtplus/2.S2.9 |
0.299 |
|
| 2008 |
Smithies O. Tea with Dr Oliver Smithies, 2007 Nobel laureate in physiology and medicine. Interview by Dr. Anthony Viera. Journal of Clinical Hypertension (Greenwich, Conn.). 10: 640-3. PMID 18772647 DOI: 10.1111/j.1751-7176.2008.08472.x |
0.191 |
|
| 2008 |
Pandya K, Cowhig J, Brackhan J, Kim HS, Hagaman J, Rojas M, Carter CW, Mao L, Rockman HA, Maeda N, Smithies O. Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 13063-8. PMID 18755891 DOI: 10.1073/Pnas.0805120105 |
0.578 |
|
| 2008 |
Smithies O. Turning pages (Nobel lecture). Chembiochem : a European Journal of Chemical Biology. 9: 1342-59. PMID 18543237 DOI: 10.1002/Cbic.200800205 |
0.297 |
|
| 2008 |
Brosnihan KB, Hodgin JB, Smithies O, Maeda N, Gallagher P. Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice. Experimental Physiology. 93: 658-64. PMID 18192335 DOI: 10.1113/Expphysiol.2007.041806 |
0.573 |
|
| 2008 |
Makhanova N, Hagaman J, Kim HS, Smithies O. Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase. Hypertension. 51: 134-40. PMID 18039983 DOI: 10.1161/Hypertensionaha.107.098897 |
0.462 |
|
| 2007 |
Hakim ZS, DiMichele LA, Doherty JT, Homeister JW, Beggs HE, Reichardt LF, Schwartz RJ, Brackhan J, Smithies O, Mack CP, Taylor JM. Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Molecular and Cellular Biology. 27: 5352-64. PMID 17526730 DOI: 10.1128/Mcb.00068-07 |
0.413 |
|
| 2007 |
Dackor R, Fritz-Six K, Smithies O, Caron K. Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age. The Journal of Biological Chemistry. 282: 18094-9. PMID 17470425 DOI: 10.1074/Jbc.M703544200 |
0.468 |
|
| 2007 |
Kakoki M, McGarrah RW, Kim HS, Smithies O. Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America. 104: 7576-81. PMID 17452647 DOI: 10.1073/Pnas.0701617104 |
0.434 |
|
| 2007 |
Yamaguchi N, Takahashi N, Xu L, Smithies O, Meissner G. Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel. The Journal of Clinical Investigation. 117: 1344-53. PMID 17431507 DOI: 10.1172/Jci29515 |
0.402 |
|
| 2007 |
Caron K, Hagaman J, Nishikimi T, Kim HS, Smithies O. Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males. Proceedings of the National Academy of Sciences of the United States of America. 104: 3420-5. PMID 17360661 DOI: 10.1073/Pnas.0611365104 |
0.489 |
|
| 2007 |
Ellmers LJ, Scott NJ, Piuhola J, Maeda N, Smithies O, Frampton CM, Richards AM, Cameron VA. Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis. Journal of Molecular Endocrinology. 38: 245-57. PMID 17293444 DOI: 10.1677/Jme.1.02138 |
0.601 |
|
| 2007 |
Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, Kim H-, Smithies O, Le TH, Coffman TM. Role of Renal Angiotensin II Type 1 Receptors in the Genesis of Hypertension: Guyton Revisited Angiotensin II Causes Hypertension and Cardiac Hypertrophy through Its Receptors in the Kidney. Proc Natl Acad Sci U S A 103: 17985–17990, 2006 Journal of the American Society of Nephrology. 18: 356-363. DOI: 10.1681/Asn.2006121393 |
0.372 |
|
| 2006 |
Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, Kim HS, Smithies O, Le TH, Coffman TM. Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proceedings of the National Academy of Sciences of the United States of America. 103: 17985-90. PMID 17090678 DOI: 10.1073/Pnas.0605545103 |
0.389 |
|
| 2006 |
Makhanova N, Sequeira-Lopez ML, Gomez RA, Kim HS, Smithies O. Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption. Hypertension. 48: 1151-9. PMID 17075030 DOI: 10.1161/01.HYP.0000249902.09036.e7 |
0.352 |
|
| 2006 |
Pandya K, Kim HS, Smithies O. Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo. Proceedings of the National Academy of Sciences of the United States of America. 103: 16864-9. PMID 17068123 DOI: 10.1073/Pnas.0607700103 |
0.428 |
|
| 2006 |
Li M, Yee D, Magnuson TR, Smithies O, Caron KM. Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice. The Journal of Clinical Investigation. 116: 2653-62. PMID 16981008 DOI: 10.1172/Jci28462 |
0.411 |
|
| 2006 |
Yasuda O, Fukuo K, Sun X, Nishitani M, Yotsui T, Higuchi M, Suzuki T, Rakugi H, Smithies O, Maeda N, Ogihara T. Apop-1, a novel protein inducing cyclophilin D-dependent but Bax/Bak-related channel-independent apoptosis. The Journal of Biological Chemistry. 281: 23899-907. PMID 16782708 DOI: 10.1074/Jbc.M512610200 |
0.49 |
|
| 2006 |
Ciavatta D, Kalantry S, Magnuson T, Smithies O. A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation. Proceedings of the National Academy of Sciences of the United States of America. 103: 9958-63. PMID 16777957 DOI: 10.1073/Pnas.0603754103 |
0.393 |
|
| 2006 |
Perrino C, Naga Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA. Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. The Journal of Clinical Investigation. 116: 1547-60. PMID 16741575 DOI: 10.1172/Jci25397 |
0.395 |
|
| 2006 |
Kakoki M, Kizer CM, Yi X, Takahashi N, Kim HS, Bagnell CR, Edgell CJ, Maeda N, Jennette JC, Smithies O. Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. The Journal of Clinical Investigation. 116: 1302-9. PMID 16604193 DOI: 10.1172/Jci26958 |
0.589 |
|
| 2006 |
Kakoki M, Kim HS, Edgell CJ, Maeda N, Smithies O, Mattson DL. Amino acids as modulators of endothelium-derived nitric oxide. American Journal of Physiology. Renal Physiology. 291: F297-304. PMID 16571593 DOI: 10.1152/Ajprenal.00417.2005 |
0.485 |
|
| 2006 |
Dackor RT, Fritz-Six K, Dunworth WP, Gibbons CL, Smithies O, Caron KM. Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Molecular and Cellular Biology. 26: 2511-8. PMID 16537897 DOI: 10.1128/Mcb.26.7.2511-2518.2006 |
0.475 |
|
| 2006 |
Makhanova N, Lee G, Takahashi N, Sequeira Lopez ML, Gomez RA, Kim HS, Smithies O. Kidney function in mice lacking aldosterone. American Journal of Physiology. Renal Physiology. 290: F61-9. PMID 16118390 DOI: 10.1152/Ajprenal.00257.2005 |
0.468 |
|
| 2005 |
Hatada S, Arnold LW, Hatada T, Cowhig JE, Ciavatta D, Smithies O. Isolating gene-corrected stem cells without drug selection. Proceedings of the National Academy of Sciences of the United States of America. 102: 16357-61. PMID 16258059 DOI: 10.1073/Pnas.0508263102 |
0.427 |
|
| 2005 |
Hagaman JR, John S, Xu L, Smithies O, Maeda N. An improved technique for tail-cuff blood pressure measurements with dark-tailed mice. Contemporary Topics in Laboratory Animal Science / American Association For Laboratory Animal Science. 44: 43-6. PMID 16138782 |
0.682 |
|
| 2005 |
Smithies O. An interview with... Oliver Smithies [interviewed by Magdalena Skipper]. Nature Reviews. Genetics. 6: 350. PMID 15880879 DOI: 10.1038/nrg1627 |
0.157 |
|
| 2005 |
Smithies O. Many little things: one geneticist's view of complex diseases. Nature Reviews. Genetics. 6: 419-25. PMID 15861211 DOI: 10.1038/Nrg1605 |
0.447 |
|
| 2005 |
Crowley SD, Gurley SB, Oliverio MI, Pazmino AK, Griffiths R, Flannery PJ, Spurney RF, Kim HS, Smithies O, Le TH, Coffman TM. Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. The Journal of Clinical Investigation. 115: 1092-9. PMID 15841186 DOI: 10.1172/Jci23378 |
0.412 |
|
| 2005 |
Nishikimi T, Hagaman JR, Takahashi N, Kim HS, Matsuoka H, Smithies O, Maeda N. Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptor-A gene. Cardiovascular Research. 66: 94-103. PMID 15769452 DOI: 10.1016/J.Cardiores.2004.12.014 |
0.592 |
|
| 2005 |
Lee G, Makhanova N, Caron K, Lopez ML, Gomez RA, Smithies O, Kim HS. Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice. Endocrinology. 146: 2650-6. PMID 15731365 DOI: 10.1210/En.2004-1102 |
0.461 |
|
| 2005 |
Fair JH, Cairns BA, Lapaglia MA, Caballero M, Pleasant WA, Hatada S, Kim HS, Gui T, Pevny L, Meyer AA, Stafford DW, Smithies O, Frelinger JA. Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro. Proceedings of the National Academy of Sciences of the United States of America. 102: 2958-63. PMID 15699326 DOI: 10.1073/Pnas.0409840102 |
0.411 |
|
| 2005 |
Caron KM, James LR, Lee G, Kim HS, Smithies O. Lifelong genetic minipumps. Physiological Genomics. 20: 203-9. PMID 15585607 DOI: 10.1152/Physiolgenomics.00221.2004 |
0.419 |
|
| 2005 |
Takahashi N, Lopez ML, Cowhig JE, Taylor MA, Hatada T, Riggs E, Lee G, Gomez RA, Kim HS, Smithies O. Ren1c homozygous null mice are hypotensive and polyuric, but heterozygotes are indistinguishable from wild-type. Journal of the American Society of Nephrology : Jasn. 16: 125-32. PMID 15563565 DOI: 10.1681/Asn.2004060490 |
0.457 |
|
| 2005 |
Crowley S, Gurley S, Oliverio M, Pazmino A, Griffiths R, Flannery P, Spurney R, Kim H, Smithies O, Le T, Coffman T. Is the kidney always the cause of hypertension? Distinct roles for the kidney and systemic tissues in blood pressure regulation by the Renin-Angiotensin system. J Clin Invest 115: 1092-1099, 2005 Journal of the American Society of Nephrology. 16: 1525-1532. DOI: 10.1681/Asn.2005040379 |
0.379 |
|
| 2004 |
Cohen SM, Hatada S, Brylawski BP, Smithies O, Kaufman DG, Cordeiro-Stone M. Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences. Genomics. 84: 475-84. PMID 15498455 DOI: 10.1016/J.Ygeno.2004.04.008 |
0.433 |
|
| 2004 |
Jiang Y, Pandya K, Smithies O, Hsu EW. Three-dimensional diffusion tensor microscopy of fixed mouse hearts. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 52: 453-60. PMID 15334561 DOI: 10.1002/Mrm.20191 |
0.331 |
|
| 2004 |
Kakoki M, Takahashi N, Jennette JC, Smithies O. Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 101: 13302-5. PMID 15326315 DOI: 10.1073/Pnas.0405449101 |
0.411 |
|
| 2004 |
Le TH, Oliverio MI, Kim HS, Salzler H, Dash RC, Howell DN, Smithies O, Bronson S, Coffman TM. A gammaGT-AT1A receptor transgene protects renal cortical structure in AT1 receptor-deficient mice. Physiological Genomics. 18: 290-8. PMID 15306694 DOI: 10.1152/Physiolgenomics.00120.2003 |
0.49 |
|
| 2004 |
Goulet JL, Pace AJ, Key ML, Byrum RS, Nguyen M, Tilley SL, Morham SG, Langenbach R, Stock JL, McNeish JD, Smithies O, Coffman TM, Koller BH. E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation. Journal of Immunology (Baltimore, Md. : 1950). 173: 1321-6. PMID 15240726 DOI: 10.4049/Jimmunol.173.2.1321 |
0.726 |
|
| 2004 |
Sequeira López ML, Pentz ES, Nomasa T, Smithies O, Gomez RA. Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened. Developmental Cell. 6: 719-28. PMID 15130496 DOI: 10.1016/S1534-5807(04)00134-0 |
0.416 |
|
| 2004 |
Kakoki M, Tsai YS, Kim HS, Hatada S, Ciavatta DJ, Takahashi N, Arnold LW, Maeda N, Smithies O. Altering the expression in mice of genes by modifying their 3' regions. Developmental Cell. 6: 597-606. PMID 15068798 DOI: 10.1016/S1534-5807(04)00094-2 |
0.614 |
|
| 2004 |
Takahashi N, Smithies O. Human genetics, animal models and computer simulations for studying hypertension. Trends in Genetics : Tig. 20: 136-45. PMID 15036807 DOI: 10.1016/J.Tig.2004.01.004 |
0.426 |
|
| 2004 |
Caron KM, James LR, Kim HS, Knowles J, Uhlir R, Mao L, Hagaman JR, Cascio W, Rockman H, Smithies O. Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene. Proceedings of the National Academy of Sciences of the United States of America. 101: 3106-11. PMID 14978280 DOI: 10.1073/Pnas.0307333101 |
0.46 |
|
| 2004 |
Bushman J, Ciavatta D, Smithies O, Kirby S. TRANSGENE-INDUCED ENHANCEMENT OF HEMATO-VASCULAR DIFFERENTIATION FROM MURINE EMBRYONIC STEM CELLS Cardiovascular Pathology. 13: 23. DOI: 10.1016/J.Carpath.2004.03.061 |
0.369 |
|
| 2003 |
SMITHIES O, POULIK MD. Two-dimensional electrophoresis of serum proteins. Nature. 177: 1033. PMID 13322019 DOI: 10.1038/1771033A0 |
0.201 |
|
| 2003 |
SMITHIES O, WALKER NF. Genetic control of some serum proteins in normal humans. Nature. 176: 1265-6. PMID 13321879 DOI: 10.1038/1761265A0 |
0.259 |
|
| 2003 |
SMITHIES O. Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults. The Biochemical Journal. 61: 629-41. PMID 13276348 DOI: 10.1042/BJ0610629 |
0.237 |
|
| 2003 |
SMITHIES O. Grouped variations in the occurrence of new protein components in normal human serum. Nature. 175: 307-8. PMID 13235885 DOI: 10.1038/175307A0 |
0.232 |
|
| 2003 |
SMITHIES O. The application of four methods for assessing protein homogeneity to crystalline beta-lactoglobulin: an anomaly in phase rule solubility tests. The Biochemical Journal. 58: 31-8. PMID 13198844 DOI: 10.1042/BJ0580031 |
0.233 |
|
| 2003 |
SMITHIES O. A dynamic osmometer for accurate measurements on small quantities of material: osmotic pressures of isoelectric beta-lactoglobulin solutions. The Biochemical Journal. 55: 57-67. PMID 13093617 DOI: 10.1042/BJ0550057 |
0.235 |
|
| 2003 |
Le TH, Kim HS, Allen AM, Spurney RF, Smithies O, Coffman TM. Physiological impact of increased expression of the AT1 angiotensin receptor. Hypertension. 42: 507-14. PMID 12963678 DOI: 10.1161/01.Hyp.0000092000.07559.57 |
0.51 |
|
| 2003 |
Fair JH, Cairns BA, Lapaglia M, Wang J, Meyer AA, Kim H, Hatada S, Smithies O, Pevny L. Induction of hepatic differentiation in embryonic stem cells by co-culture with embryonic cardiac mesoderm. Surgery. 134: 189-96. PMID 12947317 DOI: 10.1067/Msy.2003.225 |
0.379 |
|
| 2003 |
Garey J, Goodwillie A, Frohlich J, Morgan M, Gustafsson JA, Smithies O, Korach KS, Ogawa S, Pfaff DW. Genetic contributions to generalized arousal of brain and behavior. Proceedings of the National Academy of Sciences of the United States of America. 100: 11019-22. PMID 12930901 DOI: 10.1073/Pnas.1633773100 |
0.456 |
|
| 2003 |
Shi SJ, Vellaichamy E, Chin SY, Smithies O, Navar LG, Pandey KN. Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion. American Journal of Physiology. Renal Physiology. 285: F694-702. PMID 12824076 DOI: 10.1152/Ajprenal.00097.2003 |
0.441 |
|
| 2003 |
Takahashi N, Hagaman JR, Kim HS, Smithies O. Minireview: computer simulations of blood pressure regulation by the renin-angiotensin system. Endocrinology. 144: 2184-90. PMID 12746272 DOI: 10.1210/En.2002-221045 |
0.423 |
|
| 2003 |
Smithies O. Why the kidney glomerulus does not clog: a gel permeation/diffusion hypothesis of renal function. Proceedings of the National Academy of Sciences of the United States of America. 100: 4108-13. PMID 12655073 DOI: 10.1073/Pnas.0730776100 |
0.379 |
|
| 2002 |
DIXON GH, SMITHIES O. Zone electrophoresis of cabbage enzymes in starch gels. Biochimica Et Biophysica Acta. 23: 198-9. PMID 13412698 DOI: 10.1016/0006-3002(57)90305-0 |
0.193 |
|
| 2002 |
SMITHIES O, WALKER NF. Notation for serum-protein groups and the genes controlling their inheritance. Nature. 178: 694-5. PMID 13369501 DOI: 10.1038/178694A0 |
0.294 |
|
| 2002 |
McDougall KE, Perry MJ, Gibson RL, Bright JM, Colley SM, Hodgin JB, Smithies O, Tobias JH. Estrogen-induced osteogenesis in intact female mice lacking ERbeta. American Journal of Physiology. Endocrinology and Metabolism. 283: E817-23. PMID 12217900 DOI: 10.1152/ajpendo.00071.2002 |
0.312 |
|
| 2002 |
Shim EH, Kim JI, Bang ES, Heo JS, Lee JS, Kim EY, Lee JE, Park WY, Kim SH, Kim HS, Smithies O, Jang JJ, Jin DI, Seo JS. Targeted disruption of hsp70.1 sensitizes to osmotic stress. Embo Reports. 3: 857-61. PMID 12189176 DOI: 10.1093/Embo-Reports/Kvf175 |
0.381 |
|
| 2002 |
Ellmers LJ, Knowles JW, Kim HS, Smithies O, Maeda N, Cameron VA. Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis. American Journal of Physiology. Heart and Circulatory Physiology. 283: H707-14. PMID 12124219 DOI: 10.1152/Ajpheart.00677.2001 |
0.58 |
|
| 2002 |
Caron KM, James LR, Kim HS, Morham SG, Sequeira Lopez ML, Gomez RA, Reudelhuber TL, Smithies O. A genetically clamped renin transgene for the induction of hypertension. Proceedings of the National Academy of Sciences of the United States of America. 99: 8248-52. PMID 12034874 DOI: 10.1073/Pnas.112222199 |
0.468 |
|
| 2002 |
Nomura M, Durbak L, Chan J, Smithies O, Gustafsson JA, Korach KS, Pfaff DW, Ogawa S. Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor beta knockout (betaERKO) male mice. Hormones and Behavior. 41: 288-96. PMID 11971662 DOI: 10.1006/Hbeh.2002.1773 |
0.45 |
|
| 2002 |
Caron KM, Smithies O. Multiple roles of adrenomedullin revealed by animal models. Microscopy Research and Technique. 57: 55-9. PMID 11921356 DOI: 10.1002/Jemt.10046 |
0.46 |
|
| 2002 |
Kim HS, Lee G, John SW, Maeda N, Smithies O. Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proceedings of the National Academy of Sciences of the United States of America. 99: 4602-7. PMID 11904385 DOI: 10.1073/Pnas.072083799 |
0.729 |
|
| 2002 |
Makino Y, Cook DN, Smithies O, Hwang OY, Neilson EG, Turka LA, Sato H, Wells AD, Danoff TM. Impaired T cell function in RANTES-deficient mice. Clinical Immunology (Orlando, Fla.). 102: 302-9. PMID 11890717 DOI: 10.1006/Clim.2001.5178 |
0.399 |
|
| 2002 |
Takahashi N, Brooks HL, Wade JB, Liu W, Kondo Y, Ito S, Knepper MA, Smithies O. Posttranscriptional compensation for heterozygous disruption of the kidney-specific NaK2Cl cotransporter gene. Journal of the American Society of Nephrology : Jasn. 13: 604-10. PMID 11856763 |
0.387 |
|
| 2002 |
Hodgin JB, Knowles JW, Kim HS, Smithies O, Maeda N. Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice. The Journal of Clinical Investigation. 109: 541-8. PMID 11854327 DOI: 10.1172/Jci14066 |
0.57 |
|
| 2002 |
Zhu Y, Bian Z, Lu P, Karas RH, Bao L, Cox D, Hodgin J, Shaul PW, Thoren P, Smithies O, Gustafsson JA, Mendelsohn ME. Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science (New York, N.Y.). 295: 505-8. PMID 11799247 DOI: 10.1126/science.1065250 |
0.367 |
|
| 2002 |
Klinger JR, Warburton RR, Pietras L, Oliver P, Fox J, Smithies O, Hill NS. Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 282: H58-65. PMID 11748047 DOI: 10.1152/Ajpheart.2002.282.1.H58 |
0.442 |
|
| 2001 |
Athirakul K, Kim HS, Audoly LP, Smithies O, Coffman TM. Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition. Kidney International. 60: 2324-9. PMID 11737606 DOI: 10.1046/j.1523-1755.2001.00072.x |
0.256 |
|
| 2001 |
Gerlofs-Nijland ME, Assmann KJ, Dijkman HB, Dieker JW, van Son JP, Mentzel S, van Kats JP, Danser AH, Smithies O, Groenen PJ, Wetzels JF. Albuminuria in mice after injection of antibodies against aminopeptidase A: role of angiotensin II. Journal of the American Society of Nephrology : Jasn. 12: 2711-20. PMID 11729240 |
0.319 |
|
| 2001 |
Huang W, Gallois Y, Bouby N, Bruneval P, Heudes D, Belair MF, Krege JH, Meneton P, Marre M, Smithies O, Alhenc-Gelas F. Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse. Proceedings of the National Academy of Sciences of the United States of America. 98: 13330-4. PMID 11687636 DOI: 10.1073/Pnas.231476798 |
0.43 |
|
| 2001 |
Smithies O. Forty years with homologous recombination. Nature Medicine. 7: 1083-6. PMID 11590419 DOI: 10.1038/nm1001-1083 |
0.226 |
|
| 2001 |
Gilmore RC, Baker J, Dempsey S, Marchan R, Corprew RN, Byrd G, Maeda N, Smithies O, Bukoski RD, Harewood KR, Chatterjee PK. Using PAC nested deletions to order contigs and microsatellite markers at the high repetitive sequence containing Npr3 gene locus. Gene. 275: 65-72. PMID 11574153 DOI: 10.1016/S0378-1119(01)00654-0 |
0.555 |
|
| 2001 |
Goy MF, Oliver PM, Purdy KE, Knowles JW, Fox JE, Mohler PJ, Qian X, Smithies O, Maeda N. Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide. The Biochemical Journal. 358: 379-87. PMID 11513736 DOI: 10.1042/0264-6021:3580379 |
0.534 |
|
| 2001 |
Pentz ES, Lopez ML, Kim HS, Carretero O, Smithies O, Gomez RA. Ren1d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1d. Physiological Genomics. 6: 45-55. PMID 11395546 DOI: 10.1152/Physiolgenomics.2001.6.1.45 |
0.414 |
|
| 2001 |
Knowles JW, Esposito G, Mao L, Hagaman JR, Fox JE, Smithies O, Rockman HA, Maeda N. Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. The Journal of Clinical Investigation. 107: 975-84. PMID 11306601 DOI: 10.1172/Jci11273 |
0.569 |
|
| 2001 |
Hodgin JB, Krege JH, Reddick RL, Korach KS, Smithies O, Maeda N. Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice. The Journal of Clinical Investigation. 107: 333-40. PMID 11160157 DOI: 10.1172/Jci11320 |
0.535 |
|
| 2001 |
Loftin CD, Trivedi DB, Tiano HF, Clark JA, Lee CA, Epstein JA, Morham SG, Breyer MD, Nguyen M, Hawkins BM, Goulet JL, Smithies O, Koller BH, Langenbach R. Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. Proceedings of the National Academy of Sciences of the United States of America. 98: 1059-64. PMID 11158594 DOI: 10.1073/Pnas.98.3.1059 |
0.616 |
|
| 2001 |
Caron KM, Smithies O. Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proceedings of the National Academy of Sciences of the United States of America. 98: 615-9. PMID 11149956 DOI: 10.1073/Pnas.98.2.615 |
0.496 |
|
| 2001 |
Smithies O. Forty years with homologous recombinations Medicina. 61: 652. |
0.226 |
|
| 2001 |
Smithies O. Mouse solutions to human problems Medicina. 61: 665. |
0.229 |
|
| 2000 |
SMITHIES O, HILLER O. The genetic control of transferrins in humans. The Biochemical Journal. 72: 121-6. PMID 13651146 DOI: 10.1042/BJ0720121 |
0.243 |
|
| 2000 |
CONNELL GE, SMITHIES O. Human haptoglobins: estimation and purification. The Biochemical Journal. 72: 115-21. PMID 13651145 DOI: 10.1042/BJ0720115 |
0.208 |
|
| 2000 |
SMITHIES O. An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals. The Biochemical Journal. 71: 585-7. PMID 13638269 DOI: 10.1042/Bj0710585 |
0.333 |
|
| 2000 |
HORSFALL WR, SMITHIES O. Genetic control of some human serum beta-globulins. Science (New York, N.Y.). 128: 35. PMID 13555927 DOI: 10.1126/SCIENCE.128.3314.35 |
0.272 |
|
| 2000 |
SMITHIES O. Third allele at the serum beta-globulin locus in humans. Nature. 181: 1203-4. PMID 13541421 DOI: 10.1038/1811203B0 |
0.276 |
|
| 2000 |
POULIK MD, SMITHIES O. Comparison and combination of the starch-gel and filter-paper electrophoretic methods applied to human sera: two-dimensional electrophoresis. The Biochemical Journal. 68: 636-43. PMID 13522673 DOI: 10.1042/BJ0680636 |
0.201 |
|
| 2000 |
SMITHIES O. Variations in human serum beta-globulins. Nature. 180: 1482-3. PMID 13493574 DOI: 10.1038/1801482A0 |
0.263 |
|
| 2000 |
Norwood VF, Morham SG, Smithies O. Postnatal development and progression of renal dysplasia in cyclooxygenase-2 null mice. Kidney International. 58: 2291-300. PMID 11115063 DOI: 10.1046/j.1523-1755.2000.00413.x |
0.307 |
|
| 2000 |
Smithies O, Kim HS, Takahashi N, Edgell MH. Importance of quantitative genetic variations in the etiology of hypertension. Kidney International. 58: 2265-80. PMID 11115061 DOI: 10.1046/J.1523-1755.2000.00411.X |
0.478 |
|
| 2000 |
Ogawa S, Chester AE, Hewitt SC, Walker VR, Gustafsson JA, Smithies O, Korach KS, Pfaff DW. Abolition of male sexual behaviors in mice lacking estrogen receptors alpha and beta (alpha beta ERKO). Proceedings of the National Academy of Sciences of the United States of America. 97: 14737-41. PMID 11114183 DOI: 10.1073/Pnas.250473597 |
0.455 |
|
| 2000 |
Hatada S, Nikkuni K, Bentley SA, Kirby S, Smithies O. Gene correction in hematopoietic progenitor cells by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 97: 13807-11. PMID 11087825 DOI: 10.1073/Pnas.240462897 |
0.464 |
|
| 2000 |
Chulada PC, Thompson MB, Mahler JF, Doyle CM, Gaul BW, Lee C, Tiano HF, Morham SG, Smithies O, Langenbach R. Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice. Cancer Research. 60: 4705-8. PMID 10987272 |
0.325 |
|
| 2000 |
Kirby S, Walton W, Smithies O. Hematopoietic stem cells with controllable tEpoR transgenes have a competitive advantage in bone marrow transplantation. Blood. 95: 3710-5. PMID 10845901 DOI: 10.1182/Blood.V95.12.3710.012K38_3710_3715 |
0.396 |
|
| 2000 |
Takahashi N, Chernavvsky DR, Gomez RA, Igarashi P, Gitelman HJ, Smithies O. Uncompensated polyuria in a mouse model of Bartter's syndrome. Proceedings of the National Academy of Sciences of the United States of America. 97: 5434-9. PMID 10779555 DOI: 10.1073/Pnas.090091297 |
0.448 |
|
| 2000 |
Morteau O, Morham SG, Sellon R, Dieleman LA, Langenbach R, Smithies O, Sartor RB. Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2. The Journal of Clinical Investigation. 105: 469-78. PMID 10683376 DOI: 10.1172/Jci6899 |
0.436 |
|
| 2000 |
Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, Maeda N. Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. The Journal of Clinical Investigation. 105: 451-8. PMID 10683374 DOI: 10.1172/Jci8376 |
0.579 |
|
| 2000 |
Oliverio MI, Best CF, Smithies O, Coffman TM. Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II. Hypertension. 35: 550-4. PMID 10679496 DOI: 10.1161/01.Hyp.35.2.550 |
0.435 |
|
| 2000 |
Oliverio MI, Delnomdedieu M, Best CF, Li P, Morris M, Callahan MF, Johnson GA, Smithies O, Coffman TM. Abnormal water metabolism in mice lacking the type 1A receptor for ANG II. American Journal of Physiology. Renal Physiology. 278: F75-82. PMID 10644657 DOI: 10.1152/Ajprenal.2000.278.1.F75 |
0.419 |
|
| 2000 |
Le TH, Fogo A, Oliverio MI, Peterson AS, Smithies O, Coffman TM. Genetic Modifiers of Mortality and Kidney Structure in Type 1a (AT1A) Angiotensin II Receptor Deficiency Hypertension. 36: 686-687. DOI: 10.1161/01.Hyp.36.Suppl_1.686-D |
0.439 |
|
| 1999 |
Pandey KN, Oliver PM, Maeda N, Smithies O. Hypertension Associated with Decreased Testosterone Levels in Natriuretic Peptide Receptor-A Gene-Knockout and Gene-Duplicated Mutant Mouse Models1. Endocrinology. 140: 5112-5119. PMID 28204268 DOI: 10.1210/endo.140.11.7121 |
0.539 |
|
| 1999 |
Smithies O. Alexander George Ogston: 30 January 1911-29 June 1996. Biographical Memoirs of Fellows of the Royal Society. Royal Society (Great Britain). 45: 351-64. PMID 11624284 |
0.164 |
|
| 1999 |
Smithies O. Quantitative genetic variations and essential hypertension. Harvey Lectures. 95: 1-20. PMID 11446106 |
0.246 |
|
| 1999 |
Karas RH, Hodgin JB, Kwoun M, Krege JH, Aronovitz M, Mackey W, Gustafsson JA, Korach KS, Smithies O, Mendelsohn ME. Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 15133-6. PMID 10611350 DOI: 10.1073/Pnas.96.26.15133 |
0.402 |
|
| 1999 |
Nataraj C, Oliverio MI, Mannon RB, Mannon PJ, Audoly LP, Amuchastegui CS, Ruiz P, Smithies O, Coffman TM. Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway. The Journal of Clinical Investigation. 104: 1693-701. PMID 10606623 DOI: 10.1172/Jci7451 |
0.382 |
|
| 1999 |
Pandey KN, Oliver PM, Maeda N, Smithies O. Hypertension associated with decreased testosterone levels in natriuretic peptide receptor-A gene-knockout and gene-duplicated mutant mouse models. Endocrinology. 140: 5112-9. PMID 10537139 DOI: 10.1210/Endo.140.11.7121 |
0.636 |
|
| 1999 |
Takahashi N, Smithies O. Gene targeting approaches to analyzing hypertension. Journal of the American Society of Nephrology : Jasn. 10: 1598-605. PMID 10405217 |
0.404 |
|
| 1999 |
Matsukawa N, Grzesik WJ, Takahashi N, Pandey KN, Pang S, Yamauchi M, Smithies O. The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system. Proceedings of the National Academy of Sciences of the United States of America. 96: 7403-8. PMID 10377427 DOI: 10.1073/Pnas.96.13.7403 |
0.408 |
|
| 1999 |
Traynor T, Yang T, Huang YG, Krege JH, Briggs JP, Smithies O, Schnermann J. Tubuloglomerular feedback in ACE-deficient mice. The American Journal of Physiology. 276: F751-7. PMID 10330057 DOI: 10.1152/Ajprenal.1999.276.5.F751 |
0.44 |
|
| 1999 |
Klinger JR, Warburton RR, Pietras LA, Smithies O, Swift R, Hill NS. Genetic disruption of atrial natriuretic peptide causes pulmonary hypertension in normoxic and hypoxic mice. The American Journal of Physiology. 276: L868-74. PMID 10330043 DOI: 10.1152/Ajplung.1999.276.5.L868 |
0.449 |
|
| 1999 |
Kim HS, Maeda N, Oh GT, Fernandez LG, Gomez RA, Smithies O. Homeostasis in mice with genetically decreased angiotensinogen is primarily by an increased number of renin-producing cells. The Journal of Biological Chemistry. 274: 14210-7. PMID 10318840 DOI: 10.1074/Jbc.274.20.14210 |
0.624 |
|
| 1999 |
Cook DN, Smithies O, Strieter RM, Frelinger JA, Serody JS. CD8+ T cells are a biologically relevant source of macrophage inflammatory protein-1 alpha in vivo. Journal of Immunology (Baltimore, Md. : 1950). 162: 5423-8. PMID 10228020 |
0.298 |
|
| 1999 |
Fern RJ, Yesko CM, Thornhill BA, Kim HS, Smithies O, Chevalier RL. Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice. The Journal of Clinical Investigation. 103: 39-46. PMID 9884332 DOI: 10.1172/Jci4236 |
0.446 |
|
| 1999 |
Hatada S, Kuziel W, Smithies O, Maeda N. The influence of chromosomal location on the expression of two transgenes in mice. The Journal of Biological Chemistry. 274: 948-55. PMID 9873036 DOI: 10.1074/Jbc.274.2.948 |
0.596 |
|
| 1998 |
Oliverio MI, Madsen K, Best CF, Ito M, Maeda N, Smithies O, Coffman TM. Renal growth and development in mice lacking ATreceptors for angiotensin II. American Journal of Physiology. Renal Physiology. 274: F43-F50. PMID 29592628 DOI: 10.1152/ajprenal.1998.274.1.F43 |
0.54 |
|
| 1998 |
SMITHIES O, CONNELL GE, DIXON GH. Chromosomal rearrangements and the evolution of haptoglobin genes. Nature. 196: 232-6. PMID 13989613 DOI: 10.1038/196232A0 |
0.311 |
|
| 1998 |
NANCE WE, SMITHIES O. New haptoglobin alleles: a prediction confirmed. Nature. 198: 869-70. PMID 13937541 DOI: 10.1038/198869A0 |
0.198 |
|
| 1998 |
CONNELL GE, DIXON GH, SMITHIES O. Subdivision of the three common haptoglobin types based on 'hidden' diffrences. Nature. 193: 505-6. PMID 13880879 DOI: 10.1038/193505A0 |
0.211 |
|
| 1998 |
SMITHIES O. Zone electrophoresis in starch gels and its application to studies of serum proteins. Advances in Protein Chemistry. 14: 65-113. PMID 13832188 DOI: 10.1016/S0065-3233(08)60609-9 |
0.208 |
|
| 1998 |
Krege JH, Hodgin JB, Couse JF, Enmark E, Warner M, Mahler JF, Sar M, Korach KS, Gustafsson JA, Smithies O. Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Proceedings of the National Academy of Sciences of the United States of America. 95: 15677-82. PMID 9861029 DOI: 10.1073/Pnas.95.26.15677 |
0.455 |
|
| 1998 |
Oliverio MI, Kim HS, Ito M, Le T, Audoly L, Best CF, Hiller S, Kluckman K, Maeda N, Smithies O, Coffman TM. Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. Proceedings of the National Academy of Sciences of the United States of America. 95: 15496-501. PMID 9860997 DOI: 10.1073/Pnas.95.26.15496 |
0.583 |
|
| 1998 |
Thomas DW, Mannon RB, Mannon PJ, Latour A, Oliver JA, Hoffman M, Smithies O, Koller BH, Coffman TM. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. The Journal of Clinical Investigation. 102: 1994-2001. PMID 9835625 DOI: 10.1172/Jci5116 |
0.624 |
|
| 1998 |
Thresher RJ, Vitaterna MH, Miyamoto Y, Kazantsev A, Hsu DS, Petit C, Selby CP, Dawut L, Smithies O, Takahashi JS, Sancar A. Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. Science (New York, N.Y.). 282: 1490-4. PMID 9822380 DOI: 10.1126/Science.282.5393.1490 |
0.389 |
|
| 1998 |
Whitney JB, Leder A, Lewis J, Popp RA, Paszty C, Rubin EM, Shehee WR, Townes TM, Smithies O. Rapid genotyping of mice with hemoglobinopathies and globin transgenes. Biochemical Genetics. 36: 65-77. PMID 9562907 DOI: 10.1023/A:1018752219810 |
0.671 |
|
| 1998 |
Tumpey TM, Cheng H, Cook DN, Smithies O, Oakes JE, Lausch RN. Absence of macrophage inflammatory protein-1alpha prevents the development of blinding herpes stromal keratitis. Journal of Virology. 72: 3705-10. PMID 9557652 DOI: 10.1128/Jvi.72.5.3705-3710.1998 |
0.409 |
|
| 1998 |
Lewis J, Yang B, Kim R, Sierakowska H, Kole R, Smithies O, Maeda N. A common human beta globin splicing mutation modeled in mice. Blood. 91: 2152-6. PMID 9490703 DOI: 10.1182/Blood.V91.6.2152.2152_2152_2156 |
0.771 |
|
| 1998 |
Hagaman JR, Moyer JS, Bachman ES, Sibony M, Magyar PL, Welch JE, Smithies O, Krege JH, O'Brien DA. Angiotensin-converting enzyme and male fertility. Proceedings of the National Academy of Sciences of the United States of America. 95: 2552-7. PMID 9482924 DOI: 10.1073/Pnas.95.5.2552 |
0.437 |
|
| 1998 |
Oliver PM, John SW, Purdy KE, Kim R, Maeda N, Goy MF, Smithies O. Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 95: 2547-51. PMID 9482923 DOI: 10.1073/Pnas.95.5.2547 |
0.706 |
|
| 1998 |
Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. The Journal of Clinical Investigation. 101: 731-6. PMID 9466966 DOI: 10.1172/Jci1699 |
0.533 |
|
| 1998 |
Oliverio MI, Madsen K, Best CF, Ito M, Maeda N, Smithies O, Coffman TM. Renal growth and development in mice lacking AT1A receptors for angiotensin II. The American Journal of Physiology. 274: F43-50. PMID 9458822 DOI: 10.1152/Ajprenal.1998.274.1.F43 |
0.589 |
|
| 1998 |
Lindsey J, Kim H, Smithies O, Gomez RA. Angiotensinogen is Necessary for Postnatal Kidney Development • 1821 Pediatric Research. 43: 310-310. DOI: 10.1203/00006450-199804001-01844 |
0.227 |
|
| 1998 |
Fern RJ, Yesko CM, Thornhill BA, Kim H, Smithies O, Chevalier RL. Interstitial Fibrosis in Chronic Hydronephrosis is Modulated by Angiotensinogen Expression |[bull]| 1797 Pediatric Research. 43: 306-306. DOI: 10.1203/00006450-199804001-01820 |
0.434 |
|
| 1998 |
Smithies O. Alexander George Ogston 1911-1996 Historical Records of Australian Science. 12: 517. DOI: 10.1071/HR9991240517 |
0.167 |
|
| 1998 |
Kirby S, Wallon W, Smithies O. Erythropoietin-induced competitive expansion of transplanted tepor transgenic hematopoietic stem cells in vivo Experimental Hematology. 26: 814. |
0.251 |
|
| 1997 |
Oliver PM, Fox JE, Kim R, Rockman HA, Kim HS, Reddick RL, Pandey KN, Milgram SL, Smithies O, Maeda N. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A. Proceedings of the National Academy of Sciences of the United States of America. 94: 14730-5. PMID 9405681 DOI: 10.1073/Pnas.94.26.14730 |
0.579 |
|
| 1997 |
Smithies O. Theodore Cooper Memorial Lecture. A mouse view of hypertension. Hypertension. 30: 1318-24. PMID 9403547 DOI: 10.1161/01.Hyp.30.6.1318 |
0.452 |
|
| 1997 |
Lin HF, Maeda N, Smithies O, Straight DL, Stafford DW. A coagulation factor IX-deficient mouse model for human hemophilia B. Blood. 90: 3962-6. PMID 9354664 DOI: 10.1182/Blood.V90.10.3962 |
0.591 |
|
| 1997 |
Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proceedings of the National Academy of Sciences of the United States of America. 94: 12053-8. PMID 9342361 DOI: 10.1073/Pnas.94.22.12053 |
0.582 |
|
| 1997 |
Morham SG, Langenbach R, Mahler J, Smithies O. Characterization of prostaglandin H synthase 2 deficient mice and implications for mechanisms of NSAID action. Advances in Experimental Medicine and Biology. 407: 131-8. PMID 9321943 DOI: 10.1007/978-1-4899-1813-0_20 |
0.338 |
|
| 1997 |
Savinova OV, Matsukawa N, Smithies O, John SW. Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 788. PMID 9321481 DOI: 10.1007/S003359900571 |
0.636 |
|
| 1997 |
Krege JH, Moyer JS, Langenbach LL, Peng L, Zhang SH, Maeda N, Reddick RL, Smithies O. Angiotensin-converting enzyme gene and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1245-50. PMID 9261253 DOI: 10.1161/Atvb.17V07.1245 |
0.567 |
|
| 1997 |
Tian B, Meng QC, Chen YF, Krege JH, Smithies O, Oparil S. Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function. Hypertension. 30: 128-33. PMID 9231832 DOI: 10.1161/01.Hyp.30.1.128 |
0.458 |
|
| 1997 |
Tsuda H, Maynard-Currie CE, Reid LH, Yoshida T, Edamura K, Maeda N, Smithies O, Jakobovits A. Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines. Genomics. 42: 413-21. PMID 9205113 DOI: 10.1006/Geno.1997.4771 |
0.594 |
|
| 1997 |
Oliverio MI, Best CF, Kim HS, Arendshorst WJ, Smithies O, Coffman TM. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation. The American Journal of Physiology. 272: F515-20. PMID 9140053 DOI: 10.1152/Ajprenal.1997.272.4.F515 |
0.417 |
|
| 1997 |
MacTaggart TE, Ito M, Smithies O, John SW. Mouse angiotensin receptor genes Agtr1a and Agtr1b map to chromosomes 13 and 3. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 294-5. PMID 9096120 DOI: 10.1007/S003359900419 |
0.643 |
|
| 1997 |
Davisson RL, Kim HS, Krege JH, Lager DJ, Smithies O, Sigmund CD. Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes. The Journal of Clinical Investigation. 99: 1258-64. PMID 9077534 DOI: 10.1172/Jci119283 |
0.465 |
|
| 1997 |
Hilgers KF, Reddi V, Krege JH, Smithies O, Gomez RA. Aberrant renal vascular morphology and renin expression in mutant mice lacking angiotensin-converting enzyme. Hypertension. 29: 216-21. PMID 9039105 DOI: 10.1161/01.Hyp.29.1.216 |
0.456 |
|
| 1997 |
Krege JH, Kim HS, Moyer JS, Jennette JC, Peng L, Hiller SK, Smithies O. Angiotensin-converting enzyme gene mutations, blood pressures, and cardiovascular homeostasis. Hypertension. 29: 150-7. PMID 9039095 DOI: 10.1161/01.Hyp.29.1.150 |
0.508 |
|
| 1997 |
Oliverio MI, Best CF, Kim HS, Arendshorst WJ, Smithies O, Coffman TM. Angiotensin II responses in at 1A receptor-deficient mice: A role for at 1B receptors in blood pressure regulation American Journal of Physiology. 272: F521-F530. |
0.316 |
|
| 1996 |
Morham SG, Kluckman KD, Voulomanos N, Smithies O. Targeted disruption of the mouse topoisomerase I gene by camptothecin selection. Molecular and Cellular Biology. 16: 6804-9. PMID 8943335 DOI: 10.1128/Mcb.16.12.6804 |
0.481 |
|
| 1996 |
Toth LR, Smith TJ, Jones C, de Silva HV, Smithies O, Maeda N. Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting. Gene. 178: 161-8. PMID 8921909 DOI: 10.1016/0378-1119(96)00360-5 |
0.6 |
|
| 1996 |
Shesely EG, Maeda N, Kim HS, Desai KM, Krege JH, Laubach VE, Sherman PA, Sessa WC, Smithies O. Elevated blood pressures in mice lacking endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 93: 13176-81. PMID 8917564 DOI: 10.1073/Pnas.93.23.13176 |
0.597 |
|
| 1996 |
Bozza PT, Payne JL, Morham SG, Langenbach R, Smithies O, Weller PF. Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin. Proceedings of the National Academy of Sciences of the United States of America. 93: 11091-6. PMID 8855314 DOI: 10.1073/Pnas.93.20.11091 |
0.339 |
|
| 1996 |
Bronson SK, Plaehn EG, Kluckman KD, Hagaman JR, Maeda N, Smithies O. Single-copy transgenic mice with chosen-site integration. Proceedings of the National Academy of Sciences of the United States of America. 93: 9067-72. PMID 8799155 DOI: 10.1073/Pnas.93.17.9067 |
0.589 |
|
| 1996 |
Kirby SL, Cook DN, Walton W, Smithies O. Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene. Proceedings of the National Academy of Sciences of the United States of America. 93: 9402-7. PMID 8790342 DOI: 10.1073/Pnas.93.18.9402 |
0.445 |
|
| 1996 |
John SW, Veress AT, Honrath U, Chong CK, Peng L, Smithies O, Sonnenberg H. Blood pressure and fluid-electrolyte balance in mice with reduced or absent ANP. The American Journal of Physiology. 271: R109-14. PMID 8760210 |
0.619 |
|
| 1996 |
Lewis J, Yang B, Detloff P, Smithies O. Gene modification via "plug and socket" gene targeting. The Journal of Clinical Investigation. 97: 3-5. PMID 8550847 DOI: 10.1172/Jci118403 |
0.777 |
|
| 1996 |
Davisson RL, Kim HS, Krege JH, Smithies O, Sigmurid CD. Development oh transgenic mice containing a functional human, but lacking a functional mouse reninangiotensin system Faseb Journal. 10: A21. |
0.347 |
|
| 1996 |
Davisson RL, Ding Y, Kirn HS, Krege JH, Hardy DO, Catterall JF, Smithies O, Siymund CD. Development of transgenic animal models for studying the renin-angiotensin system in hypertension. Renal function and renal development Journal of Investigative Medicine. 44: 321a. |
0.263 |
|
| 1995 |
Couse JF, Curtis SW, Washburn TF, Lindzey J, Golding TS, Lubahn DB, Smithies O, Korach KS. Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene. Molecular Endocrinology (Baltimore, Md.). 9: 1441-54. PMID 8584021 DOI: 10.1210/mend.9.11.8584021 |
0.344 |
|
| 1995 |
Yang B, Kirby S, Lewis J, Detloff PJ, Maeda N, Smithies O. A mouse model for beta 0-thalassemia. Proceedings of the National Academy of Sciences of the United States of America. 92: 11608-12. PMID 8524813 DOI: 10.1073/Pnas.92.25.11608 |
0.802 |
|
| 1995 |
Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, Mahler JF, Lee CA, Goulding EH, Kluckman KD, Kim HS, Smithies O. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell. 83: 483-92. PMID 8521478 DOI: 10.1016/0092-8674(95)90126-4 |
0.437 |
|
| 1995 |
Morham SG, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jennette JC, Mahler JF, Kluckman KD, Ledford A, Lee CA, Smithies O. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell. 83: 473-82. PMID 8521477 DOI: 10.1016/0092-8674(95)90125-6 |
0.444 |
|
| 1995 |
John SW, Krege JH, Oliver PM, Hagaman JR, Hodgin JB, Pang SC, Flynn TG, Smithies O. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension. Science (New York, N.Y.). 267: 679-81. PMID 7839143 DOI: 10.1126/Science.7839143 |
0.643 |
|
| 1995 |
Smithies O, Maeda N. Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension. Proceedings of the National Academy of Sciences of the United States of America. 92: 5266-72. PMID 7777495 DOI: 10.1073/Pnas.92.12.5266 |
0.585 |
|
| 1995 |
Krege JH, John SW, Langenbach LL, Hodgin JB, Hagaman JR, Bachman ES, Jennette JC, O'Brien DA, Smithies O. Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature. 375: 146-8. PMID 7753170 DOI: 10.1038/375146A0 |
0.668 |
|
| 1995 |
Krege JH, Hodgin JB, Hagaman JR, Smithies O. A noninvasive computerized tail-cuff system for measuring blood pressure in mice. Hypertension. 25: 1111-5. PMID 7737724 DOI: 10.1161/01.Hyp.25.5.1111 |
0.41 |
|
| 1995 |
Ito M, Oliverio MI, Mannon PJ, Best CF, Maeda N, Smithies O, Coffman TM. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 3521-5. PMID 7724593 DOI: 10.1073/Pnas.92.8.3521 |
0.599 |
|
| 1995 |
Bronson SK, Smithies O, Mascarello JT. High incidence of XXY and XYY males among the offspring of female chimeras from embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 3120-3. PMID 7724525 DOI: 10.1073/Pnas.92.8.3120 |
0.353 |
|
| 1995 |
Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, Jennette JC, Coffman TM, Maeda N, Smithies O. Genetic control of blood pressure and the angiotensinogen locus. Proceedings of the National Academy of Sciences of the United States of America. 92: 2735-9. PMID 7708716 DOI: 10.1073/Pnas.92.7.2735 |
0.599 |
|
| 1995 |
Smithies O. Early days of gel electrophoresis. Genetics. 139: 1-4. PMID 7705616 |
0.188 |
|
| 1995 |
Cook DN, Beck MA, Coffman TM, Kirby SL, Sheridan JF, Pragnell IB, Smithies O. Requirement of MIP-1 alpha for an inflammatory response to viral infection. Science (New York, N.Y.). 269: 1583-5. PMID 7667639 DOI: 10.1126/Science.7667639 |
0.412 |
|
| 1995 |
Laubach VE, Shesely EG, Smithies O, Sherman PA. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proceedings of the National Academy of Sciences of the United States of America. 92: 10688-92. PMID 7479866 DOI: 10.1073/Pnas.92.23.10688 |
0.448 |
|
| 1994 |
Nadeau J, Wold B, Bernstein A, Davis R, Helwig U, Hogan B, Housman D, Klausner R, Smithies O, Graham B. Technology advancement for studying gene expression and gene function: A workshop report - National Institutes of Health Mammalian Genome. 5: 127-130. PMID 8199399 DOI: 10.1007/Bf00352341 |
0.406 |
|
| 1994 |
Smithies O, Kim HS. Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 3612-5. PMID 8170956 DOI: 10.1073/Pnas.91.9.3612 |
0.5 |
|
| 1994 |
Bronson SK, Smithies O. Altering mice by homologous recombination using embryonic stem cells. The Journal of Biological Chemistry. 269: 27155-8. PMID 7961620 |
0.344 |
|
| 1994 |
Detloff PJ, Lewis J, John SW, Shehee WR, Langenbach R, Maeda N, Smithies O. Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy. Molecular and Cellular Biology. 14: 6936-43. PMID 7935410 DOI: 10.1128/Mcb.14.10.6936 |
0.801 |
|
| 1993 |
Smithies O. Animal models of human genetic diseases. Trends in Genetics : Tig. 9: 112-6. PMID 8516844 DOI: 10.1016/0168-9525(93)90204-U |
0.458 |
|
| 1993 |
Luetteke NC, Qiu TH, Peiffer RL, Oliver P, Smithies O, Lee DC. TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell. 73: 263-78. PMID 8477445 DOI: 10.1016/0092-8674(93)90228-I |
0.419 |
|
| 1993 |
Desai NM, Bassiri H, Kim J, Koller BH, Smithies O, Barker CF, Naji A, Markmann JF. Islet allograft, islet xenograft, and skin allograft survival in CD8+ T lymphocyte-deficient mice. Transplantation. 55: 718-22. PMID 8475541 DOI: 10.1097/00007890-199304000-00006 |
0.52 |
|
| 1993 |
Shehee WR, Oliver P, Smithies O. Lethal thalassemia after insertional disruption of the mouse major adult beta-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 90: 3177-81. PMID 8475058 DOI: 10.1073/Pnas.90.8.3177 |
0.487 |
|
| 1993 |
Desai NM, Bassiri H, Odorico JS, Koller BH, Smithies O, Naji A, Barker CF, Markmann JF. Pancreatic islet allograft and xenograft survival in CD8+ T-lymphocyte-deficient recipients. Transplantation Proceedings. 25: 961-2. PMID 8442280 |
0.467 |
|
| 1993 |
Kim HS, Lyons KM, Saitoh E, Azen EA, Smithies O, Maeda N. The structure and evolution of the human salivary proline-rich protein gene family. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 3-14. PMID 8422499 DOI: 10.1007/Bf00364656 |
0.587 |
|
| 1993 |
Coffman T, Geier S, Ibrahim S, Griffiths R, Spurney R, Smithies O, Koller B, Sanfilippo F. Improved renal function in mouse kidney allografts lacking MHC class I antigens. Journal of Immunology (Baltimore, Md. : 1950). 151: 425-35. PMID 8326135 |
0.538 |
|
| 1993 |
Lubahn DB, Moyer JS, Golding TS, Couse JF, Korach KS, Smithies O. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 90: 11162-6. PMID 8248223 DOI: 10.1073/Pnas.90.23.11162 |
0.425 |
|
| 1992 |
Spriggs MK, Koller BH, Sato T, Morrissey PJ, Fanslow WC, Smithies O, Voice RF, Widmer MB, Maliszewski CR. Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses. Proceedings of the National Academy of Sciences of the United States of America. 89: 6070-4. PMID 1631092 DOI: 10.1073/Pnas.89.13.6070 |
0.581 |
|
| 1992 |
Koller BH, Smithies O. Altering genes in animals by gene targeting. Annual Review of Immunology. 10: 705-30. PMID 1591000 DOI: 10.1146/Annurev.Iy.10.040192.003421 |
0.617 |
|
| 1992 |
Markmann JF, Bassiri H, Desai NM, Odorico JS, Kim JI, Koller BH, Smithies O, Barker CF. Indefinite survival of MHC class I-deficient murine pancreatic islet allografts. Transplantation. 54: 1085-9. PMID 1465773 DOI: 10.1097/00007890-199212000-00025 |
0.521 |
|
| 1992 |
Clarke LL, Grubb BR, Gabriel SE, Smithies O, Koller BH, Boucher RC. Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis. Science (New York, N.Y.). 257: 1125-8. PMID 1380724 DOI: 10.1126/Science.257.5073.1125 |
0.599 |
|
| 1992 |
Snouwaert JN, Brigman KK, Latour AM, Malouf NN, Boucher RC, Smithies O, Koller BH. An animal model for cystic fibrosis made by gene targeting. Science (New York, N.Y.). 257: 1083-8. PMID 1380723 DOI: 10.1126/Science.257.5073.1083 |
0.625 |
|
| 1991 |
Metzenberg AB, Wurzer G, Huisman TH, Smithies O. Homology requirements for unequal crossing over in humans. Genetics. 128: 143-61. PMID 2060774 |
0.77 |
|
| 1991 |
Shesely EG, Kim HS, Shehee WR, Papayannopoulou T, Smithies O, Popovich BW. Correction of a human beta S-globin gene by gene targeting. Proceedings of the National Academy of Sciences of the United States of America. 88: 4294-8. PMID 2034673 DOI: 10.1073/Pnas.88.10.4294 |
0.471 |
|
| 1991 |
Valancius V, Smithies O. Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells. Molecular and Cellular Biology. 11: 1402-8. PMID 1996101 DOI: 10.1128/Mcb.11.3.1402 |
0.429 |
|
| 1991 |
Kim HS, Popovich BW, Shehee WR, Shesely EG, Smithies O. Problems encountered in detecting a targeted gene by the polymerase chain reaction. Gene. 103: 227-33. PMID 1889748 DOI: 10.1016/0378-1119(91)90277-I |
0.465 |
|
| 1991 |
Valancius V, Smithies O. Double-strand gap repair in a mammalian gene targeting reaction. Molecular and Cellular Biology. 11: 4389-97. PMID 1875928 DOI: 10.1128/Mcb.11.9.4389 |
0.449 |
|
| 1991 |
Reid LH, Shesely EG, Kim HS, Smithies O. Cotransformation and gene targeting in mouse embryonic stem cells. Molecular and Cellular Biology. 11: 2769-77. PMID 1850104 DOI: 10.1128/Mcb.11.5.2769 |
0.436 |
|
| 1991 |
Koller BH, Kim HS, Latour AM, Brigman K, Boucher RC, Scambler P, Wainwright B, Smithies O. Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10730-4. PMID 1720548 DOI: 10.1073/Pnas.88.23.10730 |
0.611 |
|
| 1991 |
Schwartz F, Maeda N, Smithies O, Hickey R, Edelmann W, Skoultchi A, Kucherlapati R. A dominant positive and negative selectable gene for use in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10416-20. PMID 1720540 DOI: 10.1073/Pnas.88.23.10416 |
0.575 |
|
| 1990 |
Reid LH, Gregg RG, Smithies O, Koller BH. Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 4299-303. PMID 2349238 DOI: 10.1073/Pnas.87.11.4299 |
0.613 |
|
| 1990 |
Kim HS, Smithies O, Maeda N. A physical map of the human salivary proline-rich protein gene cluster covers over 700 kbp of DNA. Genomics. 6: 260-7. PMID 2307469 DOI: 10.1016/0888-7543(90)90565-C |
0.549 |
|
| 1990 |
Henthorn PS, Smithies O, Mager DL. Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints. Genomics. 6: 226-37. PMID 2307466 DOI: 10.1016/0888-7543(90)90561-8 |
0.433 |
|
| 1990 |
Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science (New York, N.Y.). 248: 1227-30. PMID 2112266 DOI: 10.1126/Science.2112266 |
0.598 |
|
| 1989 |
Koller BH, Smithies O. Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 86: 8932-5. PMID 2682666 DOI: 10.1073/Pnas.86.22.8932 |
0.624 |
|
| 1989 |
Koller BH, Hagemann LJ, Doetschman T, Hagaman JR, Huang S, Williams PJ, First NL, Maeda N, Smithies O. Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 8927-31. PMID 2573070 DOI: 10.1073/Pnas.86.22.8927 |
0.691 |
|
| 1989 |
Endean DJ, Smithies O. Replication of plasmid DNA in fertilized Xenopus eggs is sensitive to both the topology and size of the injected template. Chromosoma. 97: 307-14. PMID 2539959 |
0.235 |
|
| 1988 |
Nandi AK, Roginski RS, Gregg RG, Smithies O, Skoultchi AI. Regulated expression of genes inserted at the human chromosomal beta-globin locus by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 85: 3845-9. PMID 3375244 DOI: 10.1073/Pnas.85.11.3845 |
0.39 |
|
| 1988 |
Lyons KM, Azen EA, Goodman PA, Smithies O. Many protein products from a few loci: assignment of human salivary proline-rich proteins to specific loci. Genetics. 120: 255-65. PMID 3220251 |
0.308 |
|
| 1988 |
Saitoh E, Isemura S, Sanada K, Kim HS, Smithies O, Maeda N. Cystatin superfamily. Evidence that family II cystatin genes are evolutionarily related to family III cystatin genes. Biological Chemistry Hoppe-Seyler. 369: 191-7. PMID 3202964 |
0.348 |
|
| 1988 |
Doetschman T, Maeda N, Smithies O. Targeted mutation of the Hprt gene in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 8583-7. PMID 3186749 DOI: 10.1073/Pnas.85.22.8583 |
0.697 |
|
| 1988 |
Kim HS, Smithies O. Recombinant fragment assay for gene targetting based on the polymerase chain reaction. Nucleic Acids Research. 16: 8887-903. PMID 3174435 DOI: 10.1093/Nar/16.18.8887 |
0.458 |
|
| 1988 |
Maeda N, Ebert DL, Doers TM, Newman M, Hasler-Rapacz J, Attie AD, Rapacz J, Smithies O. Molecular genetics of the apolipoprotein B gene in pigs in relation to atherosclerosis. Gene. 70: 213-29. PMID 2905687 DOI: 10.1016/0378-1119(88)90194-1 |
0.317 |
|
| 1988 |
Lyons KM, Stein JH, Smithies O. Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over. Genetics. 120: 267-78. PMID 2851479 |
0.35 |
|
| 1987 |
Doetschman T, Gregg RG, Maeda N, Hooper ML, Melton DW, Thompson S, Smithies O. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature. 330: 576-8. PMID 3683574 DOI: 10.1038/330576A0 |
0.693 |
|
| 1987 |
Saitoh E, Kim HS, Smithies O, Maeda N. Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family. Gene. 61: 329-38. PMID 3446578 DOI: 10.1016/0378-1119(87)90196-X |
0.537 |
|
| 1987 |
Skoultchi AI, Nandi A, Roginski RS, Gregg RG, Smithies O. Expression of genes inserted at the human beta-globin locus by homologous recombination. Progress in Clinical and Biological Research. 251: 581-94. PMID 2829231 |
0.364 |
|
| 1987 |
Song KY, Schwartz F, Maeda N, Smithies O, Kucherlapati R. Accurate modification of a chromosomal plasmid by homologous recombination in human cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 6820-4. PMID 2821545 DOI: 10.1073/Pnas.84.19.6820 |
0.61 |
|
| 1986 |
Gregg RG, Smithies O. Targeted modification of human chromosomal genes. Cold Spring Harbor Symposia On Quantitative Biology. 51: 1093-9. PMID 3472754 |
0.329 |
|
| 1986 |
Boggs SS, Gregg RG, Borenstein N, Smithies O. Efficient transformation and frequent single-site, single-copy insertion of DNA can be obtained in mouse erythroleukemia cells transformed by electroporation. Experimental Hematology. 14: 988-94. PMID 3464450 |
0.27 |
|
| 1986 |
Smithies O. Direct alteration of a gene in the human genome. Journal of Inherited Metabolic Disease. 9: 92-7. PMID 3097420 |
0.319 |
|
| 1986 |
Maeda N, Smithies O. The evolution of multigene families: human haptoglobin genes. Annual Review of Genetics. 20: 81-108. PMID 2880559 DOI: 10.1146/Annurev.Ge.20.120186.000501 |
0.553 |
|
| 1986 |
Maeda N, McEvoy SM, Harris HF, Huisman TH, Smithies O. Polymorphisms in the human haptoglobin gene cluster: chromosomes with multiple haptoglobin-related (Hpr) genes. Proceedings of the National Academy of Sciences of the United States of America. 83: 7395-9. PMID 2876426 DOI: 10.1073/Pnas.83.19.7395 |
0.588 |
|
| 1986 |
Henthorn PS, Mager DL, Huisman TH, Smithies O. A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 83: 5194-8. PMID 2425363 DOI: 10.1073/Pnas.83.14.5194 |
0.444 |
|
| 1986 |
Smithies O, Powers PA. Gene conversions and their relation to homologous chromosome pairing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 312: 291-302. PMID 2421362 |
0.38 |
|
| 1986 |
Powers PA, Smithies O. Short gene conversions in the human fetal globin gene region: a by-product of chromosome pairing during meiosis? Genetics. 112: 343-58. PMID 2416635 |
0.377 |
|
| 1985 |
Li Q, Powers PA, Smithies O. Nucleotide sequence of 16-kilobase pairs of DNA 5' to the human epsilon-globin gene. The Journal of Biological Chemistry. 260: 14901-10. PMID 4066658 |
0.34 |
|
| 1985 |
Mager DL, Henthorn PS, Smithies O. A Chinese G gamma + (A gamma delta beta)zero thalassemia deletion: comparison to other deletions in the human beta-globin gene cluster and sequence analysis of the breakpoints. Nucleic Acids Research. 13: 6559-75. PMID 2997715 DOI: 10.1093/Nar/13.18.6559 |
0.445 |
|
| 1985 |
Smithies O, Gregg RG, Boggs SS, Koralewski MA, Kucherlapati RS. Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination. Nature. 317: 230-4. PMID 2995814 DOI: 10.1038/317230A0 |
0.374 |
|
| 1985 |
Maeda N, Kim HS, Azen EA, Smithies O. Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system. The Journal of Biological Chemistry. 260: 11123-30. PMID 2993301 |
0.294 |
|
| 1985 |
Henthorn PS, Smithies O, Nakatsuji T, Felice AE, Gardiner MB, Reese AL, Huisman TH. (A gamma delta beta)0-Thalassaemia in Blacks is due to a deletion of 34 kbp of DNA. British Journal of Haematology. 59: 343-56. PMID 2578804 DOI: 10.1111/j.1365-2141.1985.tb02999.x |
0.307 |
|
| 1984 |
Smithies O, Koralewski MA, Song KY, Kucherlapati RS. Homologous recombination with DNA introduced into mammalian cells. Cold Spring Harbor Symposia On Quantitative Biology. 49: 161-70. PMID 6597754 DOI: 10.1101/Sqb.1984.049.01.019 |
0.274 |
|
| 1984 |
Devereux J, Haeberli P, Smithies O. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Research. 12: 387-95. PMID 6546423 DOI: 10.1093/Nar/12.1Part1.387 |
0.324 |
|
| 1984 |
Kucherlapati RS, Eves EM, Song KY, Morse BS, Smithies O. Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA. Proceedings of the National Academy of Sciences of the United States of America. 81: 3153-7. PMID 6328502 DOI: 10.1073/Pnas.81.10.3153 |
0.431 |
|
| 1984 |
Maeda N, Yang F, Barnett DR, Bowman BH, Smithies O. Duplication within the haptoglobin Hp2 gene. Nature. 309: 131-5. PMID 6325933 DOI: 10.1038/309131A0 |
0.534 |
|
| 1984 |
Powers PA, Altay C, Huisman TH, Smithies O. Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma. Nucleic Acids Research. 12: 7023-34. PMID 6091051 DOI: 10.1093/Nar/12.18.7023 |
0.439 |
|
| 1984 |
Azen E, Lyons KM, McGonigal T, Barrett NL, Clements LS, Maeda N, Vanin EF, Carlson DM, Smithies O. Clones from the human gene complex coding for salivary proline-rich proteins. Proceedings of the National Academy of Sciences of the United States of America. 81: 5561-5. PMID 6089212 DOI: 10.1073/Pnas.81.17.5561 |
0.559 |
|
| 1983 |
Vanin EF, Henthorn PS, Kioussis D, Grosveld F, Smithies O. Unexpected relationships between four large deletions in the human beta-globin gene cluster. Cell. 35: 701-9. PMID 6652684 DOI: 10.1016/0092-8674(83)90103-4 |
0.324 |
|
| 1983 |
Roginski RS, Skoultchi AI, Henthorn P, Smithies O, Hsiung N, Kucherlapati R. Coordinate modulation of transfected HSV thymidine kinase and human globin genes. Cell. 35: 149-55. PMID 6313221 DOI: 10.1016/0092-8674(83)90217-9 |
0.375 |
|
| 1983 |
Maeda N, Bliska JB, Smithies O. Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 80: 5012-6. PMID 6308666 DOI: 10.1073/Pnas.80.16.5012 |
0.549 |
|
| 1982 |
Shen SH, Smithies O. Human globin psi B2 is not a globin-related sequence. Nucleic Acids Research. 10: 7809-18. PMID 6897566 DOI: 10.1093/Nar/10.23.7809 |
0.411 |
|
| 1982 |
Hsiung N, Roginski RS, Henthorn P, Smithies O, Kucherlapati R, Skoultchi AI. Introduction and expression of a fetal human globin gene in mouse fibroblasts. Molecular and Cellular Biology. 2: 401-11. PMID 6180305 DOI: 10.1128/Mcb.2.4.401 |
0.456 |
|
| 1982 |
Smithies O. The control of globin and other eukaryotic genes. Journal of Cellular Physiology. Supplement. 1: 137-43. PMID 6175650 |
0.329 |
|
| 1981 |
Shen SH, Slightom JL, Smithies O. A history of the human fetal globin gene duplication. Cell. 26: 191-203. PMID 7332928 |
0.343 |
|
| 1981 |
Poulik MD, Shinnick CS, Smithies O. Partial amino acid sequences of human and dog post-gamma globulins. Molecular Immunology. 18: 569-72. PMID 7311984 |
0.238 |
|
| 1981 |
Smithies O, Engels WR, Devereux JR, Slightom JL, Shen S. Base substitutions, length differences and DNA strand asymmetries in the human G gamma and A gamma fetal globin gene region. Cell. 26: 345-53. PMID 6173131 DOI: 10.1016/0092-8674(81)90203-8 |
0.344 |
|
| 1980 |
Slightom JL, Blechl AE, Smithies O. Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes. Cell. 21: 627-38. PMID 7438203 DOI: 10.1016/0092-8674(80)90426-2 |
0.354 |
|
| 1980 |
Efstratiadis A, Posakony JW, Maniatis T, Lawn RM, O'Connell C, Spritz RA, DeRiel JK, Forget BG, Weissman SM, Slightom JL, Blechl AE, Smithies O, Baralle FE, Shoulders CC, Proudfoot NJ. The structure and evolution of the human beta-globin gene family. Cell. 21: 653-68. PMID 6985477 DOI: 10.1016/0092-8674(80)90429-8 |
0.37 |
|
| 1980 |
Vanin EF, Goldberg GI, Tucker PW, Smithies O. A mouse alpha-globin-related pseudogene lacking intervening sequences. Nature. 286: 222-6. PMID 6250049 DOI: 10.1038/286222A0 |
0.644 |
|
| 1979 |
Poulik MD, Smithies O. Partial amino acid sequences of rabbit and rat beta 2-microglobulins. Molecular Immunology. 16: 731-4. PMID 93696 |
0.243 |
|
| 1978 |
Smithies O, Blechl AE, Denniston-Thompson K, Newell N, Richards JE, Slightom JL, Tucker PW, Blattner FR. Cloning human fetal gamma globin and mouse alpha-type globin DNA: characterization and partial sequencing. Science (New York, N.Y.). 202: 1284-9. PMID 725604 DOI: 10.1126/Science.725604 |
0.745 |
|
| 1978 |
Blattner FR, Blechl AE, Denniston-Thompson K, Faber HE, Richards JE, Slightom JL, Tucker PW, Smithies O. Cloning human fetal gamma globin and mouse alpha-type globin DNA: preparation and screening of shotgun collections. Science (New York, N.Y.). 202: 1279-84. PMID 725603 DOI: 10.1126/Science.725603 |
0.731 |
|
| 1978 |
Freedlender EF, Taichman L, Smithies O. Segregation of some chromosomal proteins during cell replication. Cold Spring Harbor Symposia On Quantitative Biology. 42: 417-20. PMID 277355 |
0.25 |
|
| 1978 |
Frangione B, Franklin EC, Smithies O. Unusual genes at the aminoterminus of human immunoglobulin variants. Nature. 273: 400-1. PMID 96346 |
0.347 |
|
| 1978 |
Wessels BW, McKean DJ, Lien NC, Shinnick C, DeLuca PM, Smithies O. Amino Acid Sequence Determination of Proteins Labeled in Tritium Gas by Microwave Discharge Radiation Research. 74: 35. DOI: 10.2307/3574755 |
0.316 |
|
| 1977 |
Ballou B, Smithies O. A simplified chloral hydrate electrophoresis system for analysis of biological membranes. Analytical Biochemistry. 80: 616-23. PMID 889098 |
0.185 |
|
| 1977 |
Blattner FR, Williams BG, Blechl AE, Denniston-Thompson K, Faber HE, Furlong L, Grunwald DJ, Kiefer DO, Moore DD, Schumm JW, Sheldon EL, Smithies O. Charon phages: safer derivatives of bacteriophage lambda for DNA cloning. Science (New York, N.Y.). 196: 161-9. PMID 847462 DOI: 10.1126/Science.847462 |
0.545 |
|
| 1977 |
Freedlender EF, Taichman L, Smithies O. Nonrandom distribution of chromosomal proteins during cell replication. Biochemistry. 16: 1802-8. PMID 557988 |
0.246 |
|
| 1977 |
Walker I, Smithies O, Ballou B, Freedlender E, Shinnick C. Protein sequencing with radioisotopes Trends in Biochemical Sciences. 2: N179-N184. DOI: 10.1016/0968-0004(77)90063-9 |
0.224 |
|
| 1976 |
Ballou B, McKean DJ, Freedlender EF, Smithies O. HLA membrane antigens: sequencing by intrinsic radioactivity. Proceedings of the National Academy of Sciences of the United States of America. 73: 4487-91. PMID 794879 DOI: 10.1073/Pnas.73.12.4487 |
0.364 |
|
| 1976 |
Faber HE, Kucherlapati RS, Poulik MD, Ruddle FH, Smithies O. beta2-microglobulin locus on human chromosome 15. Somatic Cell Genetics. 2: 141-53. PMID 69326 DOI: 10.1007/Bf01542627 |
0.316 |
|
| 1976 |
Kucherlapati RS, Faber HE, Poulik MD, Ruddle FH, Smithies O. Assignment of the gene for beta-2-microglobulin to human chromosome 15. Cytogenetics and Cell Genetics. 16: 178-80. PMID 61837 DOI: 10.1159/000130584 |
0.427 |
|
| 1975 |
Poulik MD, Farrah D, Malek GH, Shinnick CJ, Smithies O. Low molecular weight urinary proteins. I. Partial amino acid sequences of the retinol-binding proteins of man and dog. Biochimica Et Biophysica Acta. 412: 326-34. PMID 1103975 |
0.222 |
|
| 1975 |
Shinnick TM, Lund E, Smithies O, Blattner FR. Hybridization of labeled RNA to DNA in agarose gels. Nucleic Acids Research. 2: 1911-29. PMID 1103090 DOI: 10.1093/Nar/2.10.1911 |
0.553 |
|
| 1974 |
McKean DJ, Peters EH, Waldby JI, Smithies O. Amino acid sequence determination with radioactive proteins. Biochemistry. 13: 3048-51. PMID 4841052 |
0.22 |
|
| 1974 |
Finlayson JS, Potter M, Shinnick CS, Smithies O. Components of the major urinary protein complex of inbred mice: determination of NH2-terminal sequences and comparison with homologous components from wild mice. Biochemical Genetics. 11: 325-35. PMID 4838000 |
0.336 |
|
| 1974 |
Smithies O. Letter: Recombinant DNA molecules. Genetics. 77: 819-20. PMID 4608059 |
0.227 |
|
| 1974 |
Smithies O. Immunoglobulin genes: arranged in tandem or in parallel? Cold Spring Harbor Symposia On Quantitative Biology. 38: 725-37. PMID 4524785 |
0.336 |
|
| 1973 |
Fett JW, Deutsch HF, Smithies O. Hinge-region deletion localized in the IgG-globulin Mcg. Immunochemistry. 10: 115-8. PMID 4727433 DOI: 10.1016/0019-2791(73)90238-3 |
0.232 |
|
| 1972 |
Smithies O, Poulik MD. Initiation of protein synthesis at an unusual position in an immunoglobulin gene? Science (New York, N.Y.). 175: 187-9. PMID 5008437 |
0.302 |
|
| 1972 |
Smithies O, Poulik MD. Dog homologue of human 2 -microglobulin. Proceedings of the National Academy of Sciences of the United States of America. 69: 2914-7. PMID 4507614 |
0.228 |
|
| 1972 |
Kornguth SE, Kozel LR, Smithies O. Probable identity of tissue specific histone with encephalitogenic protein. Nature: New Biology. 237: 49-50. PMID 4503744 |
0.22 |
|
| 1971 |
Sung MT, Dixon GH, Smithies O. Phosphorylation and synthesis of histones in regenerating rat liver. The Journal of Biological Chemistry. 246: 1358-64. PMID 5547589 |
0.19 |
|
| 1971 |
Smithies O, Gibson D, Fanning EM, Goodfliesh RM, Gilman JG, Ballantyne DL. Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac. Biochemistry. 10: 4912-21. PMID 5134536 DOI: 10.1021/bi00802a013 |
0.499 |
|
| 1971 |
Poulik MD, Ballantyne DL, Shinnick CJ, Smithies O. Partial amino acid sequences of two urinary proteins characteristic of tubular proteinemia. The Journal of Laboratory and Clinical Medicine. 78: 822. PMID 5128865 |
0.223 |
|
| 1971 |
Gibson D, Levanon M, Smithies O. Heterogeneity of normal human immunoglobulin light chains. Nonallelic variation in the constant region of lambda chains. Biochemistry. 10: 3114-22. PMID 4108342 |
0.229 |
|
| 1971 |
Smithies O, Gibson DM, Fanning EM, Percy ME, Parr DM, Connell GE. Deletions in immunoglobulin polypeptide chains as evidence for breakage and repair in DNA. Science (New York, N.Y.). 172: 574-7. PMID 4101951 DOI: 10.1126/science.172.3983.574 |
0.556 |
|
| 1970 |
Smithies O. Pathways through networks of branched DNA. Science (New York, N.Y.). 169: 882-3. PMID 5432585 |
0.205 |
|
| 1969 |
Sung M, Smithies O. Differential elution of histones from gel-trapped nuclei. Biopolymers. 7: 39-58. PMID 5772420 DOI: 10.1002/bip.1969.360070105 |
0.194 |
|
| 1969 |
Azen EA, Smithies O, Hiller O. High-voltage starch-gel electrophoresis in the study of post-albumin proteins and C'3(beta 1-c-globulin) polymorphism. Biochemical Genetics. 3: 215-28. PMID 5409404 DOI: 10.1007/BF00521138 |
0.239 |
|
| 1968 |
Gilman JG, Smithies O. Fetal hemoglobin variants in mice. Science (New York, N.Y.). 160: 885-6. PMID 5647833 |
0.305 |
|
| 1968 |
Wegmann TG, Smithies O. Improvement of the microtiter hemagglutination method. Transfusion. 8: 47. PMID 4965859 |
0.181 |
|
| 1968 |
Smithies O. Genetics of variability. Brookhaven Symposia in Biology. 21: 243-58. PMID 4180687 |
0.208 |
|
| 1968 |
Azen EA, Smithies O. Genetic polymorphism of C'3(beta1C-globulin) in human serum. Science (New York, N.Y.). 162: 905-7. PMID 4176438 DOI: 10.1126/science.162.3856.905 |
0.269 |
|
| 1967 |
Claflin AJ, Smithies O. Antibody-producing cells in division. Science (New York, N.Y.). 157: 1561-2. PMID 5341450 |
0.217 |
|
| 1967 |
Smithies O. Antibody variability. Somatic recombination between the elements of "antibody gene pairs" may explain antibody variability. Science (New York, N.Y.). 157: 267-73. PMID 4165728 DOI: 10.1126/science.157.3786.267 |
0.232 |
|
| 1967 |
Crick FHC, Hood L, Smithies O, Dreyer WJ, Milstein C, Papermaster BW, Mitchison NA, Cebra JJ, Talmage DW, Baglioni C, Edelman GM, Jerne NK. General Discussion on Theories of Antibody Variability Cold Spring Harbor Symposia On Quantitative Biology. 32: 169-172. DOI: 10.1101/Sqb.1967.032.01.024 |
0.185 |
|
| 1967 |
Smithies O. The Genetic Basis of Antibody Variability Cold Spring Harbor Symposia On Quantitative Biology. 32: 161-168. DOI: 10.1101/SQB.1967.032.01.023 |
0.205 |
|
| 1966 |
Connell GE, Smithies O, Dixon GH. Gene action in the human haptoglobins. II. Isolation and physical characterization of alpha polypeptide chains. Journal of Molecular Biology. 21: 225-9. PMID 5972462 DOI: 10.1016/0022-2836(66)90093-3 |
0.292 |
|
| 1966 |
Smithies O, Connell GE, Dixon GH. Gene action in the human haptoglobins. I. Dissociation into constituent polypeptide chains. Journal of Molecular Biology. 21: 213-24. PMID 5972461 DOI: 10.1016/0022-2836(66)90092-1 |
0.328 |
|
| 1966 |
Claflin AJ, Smithies O, Meyer RK. Antibody responses in bursa-deficient chickens. Journal of Immunology (Baltimore, Md. : 1950). 97: 693-9. PMID 4959015 |
0.214 |
|
| 1966 |
Smithies O. Somatic mutations and proteins. Proceedings of the Royal Society of London. Series B, Biological Sciences. 164: 320-7. PMID 4379521 |
0.216 |
|
| 1966 |
Ceppellini R, Dray S, Fahey JL, Franklin EC, Fudenberg H, Gell PG, Goodman HC, Grubb R, Harboe M, Kirk RL, Oudin J, Ropartz C, Smithies O, Steinberg AG, Trnka Z. [Nomenclature of genetically determined characteristics of human immunoglobulins]. Humangenetik. 2: 317-22. PMID 4168284 |
0.249 |
|
| 1966 |
Wegmann TG, Smithies O. A Simple Hemagglutination System Requiring Small Amounts of Red Cells and Antibodies Transfusion. 6: 67-73. DOI: 10.1111/j.1537-2995.1966.tb04696.x |
0.22 |
|
| 1965 |
Smithies O. Antibody Induction and Tolerance. Science (New York, N.Y.). 149: 151-6. PMID 17734491 DOI: 10.1126/Science.149.3680.151 |
0.404 |
|
| 1965 |
SMITHIES O. CHARACTERIZATION OF GENETIC VARIANTS OF BLOOD PROTEINS. Vox Sanguinis. 10: 359-62. PMID 14332941 |
0.254 |
|
| 1965 |
AZEN EA, ORR S, SMITHIES O. STARCH-GEL ELECTROPHORESIS OF ERYTHROCYTE STROMA. The Journal of Laboratory and Clinical Medicine. 65: 440-9. PMID 14261325 |
0.2 |
|
| 1965 |
Smithies O. Chromosomal rearrangements and protein structure. Bibliotheca Haematologica. 23: 373-4. PMID 5867127 |
0.228 |
|
| 1965 |
Smithies O. Disulfide-bond cleavage and formation in proteins. Science (New York, N.Y.). 150: 1595-8. PMID 5866656 |
0.196 |
|
| 1965 |
Smithies O. Characterization of genetic variants of blood proteins. Bibliotheca Haematologica. 23: 1175-7. PMID 4957215 |
0.254 |
|
| 1964 |
SMITHIES O. CHROMOSOMAL REARRANGEMENTS AND PROTEIN STRUCTURE. Cold Spring Harbor Symposia On Quantitative Biology. 29: 309-19. PMID 14280817 |
0.228 |
|
| 1964 |
SMITHIES O. GEL ELECTROPHORESIS: INTRODUCTORY REMARKS. Annals of the New York Academy of Sciences. 121: 309. PMID 14240531 |
0.197 |
|
| 1964 |
SMITHIES O. STARCH-GEL ELECTROPHORESIS. Metabolism: Clinical and Experimental. 13: SUPPL:974-84. PMID 14228776 |
0.19 |
|
| 1964 |
Condliffe P, Craig L, Ferguson K, Lebovitz H, Lewis U, Li C, Meites J, Parcells A, Pierce J, Raben M, Smithies O, Steinberg D, Tiselius A. Summary of the discussion for session No. 1 of the section on methods Metabolism. 13: 1003. DOI: 10.1016/S0026-0495(64)80019-6 |
0.183 |
|
| 1963 |
SMITHIES O. GAMMA-GLOBULIN VARIABILITY: A GENETIC HYPOTHESIS. Nature. 199: 1231-6. PMID 14074584 |
0.217 |
|
| 1963 |
NANCE WE, CLAFLIN A, SMITHIES O. LACTIC DEHYDROGENASE: GENETIC CONTROL IN MAN. Science (New York, N.Y.). 142: 1075-7. PMID 14068226 |
0.22 |
|
| 1960 |
HARRIS H, LAWLER SD, ROBSON EB, SMITHIES O. The occurrence of two unusual serum protein phenotypes in a single pedigree. Annals of Human Genetics. 24: 63-9. PMID 14399953 DOI: 10.1111/j.1469-1809.1959.tb01715.x |
0.236 |
|
| 1959 |
Giblett ER, Hickman CG, Smithies O. Serum transferrins Nature. 183: 1589-1590. PMID 13666824 DOI: 10.1038/1831589a0 |
0.223 |
|
| 1948 |
OGSTON AG, SMITHIES O. Some thermodynamic and kinetic aspects of metabolic phosphorylation. Physiological Reviews. 28: 283-303. PMID 18874569 |
0.4 |
|
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