Keith P. Klugman - Publications

Affiliations: 
Epidemiology Emory University, Atlanta, GA 
Area:
Epidemiology, Public Health

386 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Egorova E, Kumar N, Gladstone RA, Urban Y, Voropaeva E, Chaplin AV, Rumiantseva E, Svistunova TS, Hawkins PA, Klugman KP, Breiman RF, McGee L, Bentley SD, Lo SW. Key features of pneumococcal isolates recovered in Central and Northwestern Russia in 2011-2018 determined through whole-genome sequencing. Microbial Genomics. 8. PMID 36112007 DOI: 10.1099/mgen.0.000851  0.381
2021 Almeida SCG, Lo SW, Hawkins PA, Gladstone RA, Cassiolato AP, Klugman KP, Breiman RF, Bentley SD, McGee L, Brandileone MC. Genomic surveillance of invasive isolates in the period pre-PCV10 and post-PCV10 introduction in Brazil. Microbial Genomics. 7. PMID 34609274 DOI: 10.1099/mgen.0.000635  0.329
2021 Gagetti P, Lo SW, Hawkins PA, Gladstone RA, Regueira M, Faccone D, Sireva-Argentina Group, Klugman KP, Breiman RF, McGee L, Bentley SD, Corso A. Population genetic structure, serotype distribution and antibiotic resistance of causing invasive disease in children in Argentina. Microbial Genomics. 7. PMID 34586054 DOI: 10.1099/mgen.0.000636  0.366
2021 Nagaraj G, Govindan V, Ganaie F, Venkatesha VT, Hawkins PA, Gladstone RA, McGee L, Breiman RF, Bentley SD, Klugman KP, Lo SW, Ravikumar KL. genomic datasets from an Indian population describing pre-vaccine evolutionary epidemiology using a whole genome sequencing approach. Microbial Genomics. 7. PMID 34494953 DOI: 10.1099/mgen.0.000645  0.354
2021 Senghore M, Tientcheu PE, Worwui AK, Jarju S, Okoi C, Suso SMS, Foster-Nyarko E, Ebruke C, Sonko M, Kourna MH, Agossou J, Tsolenyanu E, Renner LA, Ansong D, Sanneh B, ... ... Klugman KP, et al. Phylogeography and resistome of pneumococcal meningitis in West Africa before and after vaccine introduction. Microbial Genomics. 7. PMID 34328412 DOI: 10.1099/mgen.0.000506  0.37
2020 Klugman KP, Rodgers GL. Time for a third-generation pneumococcal conjugate vaccine. The Lancet. Infectious Diseases. PMID 32702301 DOI: 10.1016/S1473-3099(20)30513-2  0.363
2020 Chaguza C, Senghore M, Bojang E, Gladstone RA, Lo SW, Tientcheu PE, Bancroft RE, Worwui A, Foster-Nyarko E, Ceesay F, Okoi C, McGee L, Klugman KP, Breiman RF, Barer MR, et al. Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation. Nature Communications. 11: 3442. PMID 32651390 DOI: 10.1038/S41467-020-17327-W  0.322
2020 Sobanjo-Ter Meulen A, Liljestrand J, Lawn JE, Hombach J, Smith J, Dickson KE, Munoz FM, Omer SB, Williams BA, Klugman KP. Preparing to introduce new maternal immunizations in low- and lower-middle-income countries: A report from the Bill & Melinda Gates Foundation convening "Allies in Maternal and Newborn Care"; May 3-4, 2018. Vaccine. PMID 32418791 DOI: 10.1016/J.Vaccine.2020.04.075  0.324
2019 Alderson MR, LaForce FM, Sobanjo-Ter Meulen A, Hwang A, Preziosi MP, Klugman KP. Eliminating Meningococcal Epidemics From the African Meningitis Belt: The Case for Advanced Prevention and Control Using Next-Generation Meningococcal Conjugate Vaccines. The Journal of Infectious Diseases. 220: S274-S278. PMID 31671447 DOI: 10.1093/Infdis/Jiz297  0.4
2019 Howard LM, Zhu Y, Griffin MR, Edwards KM, Williams JV, Gil AI, Vidal JE, Klugman KP, Lanata CF, Grijalva CG. Nasopharyngeal Pneumococcal Density during Asymptomatic Respiratory Virus Infection and Risk for Subsequent Acute Respiratory Illness. Emerging Infectious Diseases. 25: 2040-2047. PMID 31625844 DOI: 10.3201/Eid2511.190157  0.327
2019 Simões EAF, Nunes MC, Carosone-Link P, Madimabe R, Ortiz JR, Neuzil KM, Klugman KP, Cutland CL, Madhi SA. Trivalent influenza vaccination randomized control trial of pregnant women and adverse fetal outcomes. Vaccine. PMID 31331777 DOI: 10.1016/J.Vaccine.2019.07.024  0.316
2019 Lo SW, Gladstone RA, van Tonder AJ, Lees JA, du Plessis M, Benisty R, Givon-Lavi N, Hawkins PA, Cornick JE, Kwambana-Adams B, Law PY, Ho PL, Antonio M, Everett DB, Dagan R, ... ... Klugman KP, et al. Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study. The Lancet. Infectious Diseases. PMID 31196809 DOI: 10.1016/S1473-3099(19)30297-X  0.438
2019 Johnstone SL, Moore DP, Klugman KP, Madhi SA, Groome MJ. Epidemiology of invasive bacterial infections in pneumococcal conjugate vaccine-vaccinated and -unvaccinated children under 5 years of age in Soweto, South Africa: a cohort study from a high-HIV burden setting. Paediatrics and International Child Health. 1-8. PMID 31156062 DOI: 10.1080/20469047.2019.1623572  0.422
2019 Gladstone RA, Lo SW, Lees JA, Croucher NJ, van Tonder AJ, Corander J, Page AJ, Marttinen P, Bentley LJ, Ochoa TJ, Ho PL, du Plessis M, Cornick JE, Kwambana-Adams B, Benisty R, ... ... Klugman KP, et al. International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact. Ebiomedicine. PMID 31003929 DOI: 10.1016/J.Ebiom.2019.04.021  0.444
2019 Klugman KP, Rodgers GL. Population versus individual protection by pneumococcal conjugate vaccination. Lancet (London, England). PMID 31000193 DOI: 10.1016/S0140-6736(19)30039-X  0.356
2019 Sobanjo-Ter Meulen A, Munoz FM, Kaslow DC, Klugman KP, Omer SB, Vora P, Stergachis A. Maternal interventions vigilance harmonization in low- and middle-income countries: Stakeholder meeting report; Amsterdam, May 1-2, 2018. Vaccine. PMID 30955981 DOI: 10.1016/J.Vaccine.2019.03.060  0.351
2019 Bresee JS, McKinlay MA, Abramson J, Klugman KP, Wairagkar N. Global Funders Consortium for Universal Influenza Vaccine Development. Vaccine. 37: 211-213. PMID 30503660 DOI: 10.1016/J.Vaccine.2018.11.037  0.373
2019 Howard LM, Zhu Y, Griffin M, Edwards K, Williams JV, Gil A, Vidal JE, Klugman K, Lanata C, Grijalva CG. 2617. Increased Nasopharyngeal Pneumococcal Density During Asymptomatic Respiratory Virus Infection Is Associated with Subsequent Development of Acute Respiratory Illness Open Forum Infectious Diseases. 6: S910-S911. DOI: 10.1093/Ofid/Ofz360.2295  0.329
2018 Klugman KP, Black S. Impact of existing vaccines in reducing antibiotic resistance: Primary and secondary effects. Proceedings of the National Academy of Sciences of the United States of America. 115: 12896-12901. PMID 30559195 DOI: 10.1073/Pnas.1721095115  0.491
2018 Klugman KP, Madhi SA, Ginsburg AS, Rodgers GL. The role of bacterial vaccines in the prevention of influenza mortality. The Lancet. Global Health. 6: e1268-e1269. PMID 30420025 DOI: 10.1016/S2214-109X(18)30445-5  0.398
2018 Althouse BM, Flasche S, Minh LN, Thiem VD, Hashizume M, Ariyoshi K, Anh DD, Rodgers GL, Klugman KP, Hu H, Yoshida LM. Seasonality of respiratory viruses causing hospitalizations for acute respiratory infections in children in Nha Trang, Vietnam. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. PMID 30118916 DOI: 10.1016/J.Ijid.2018.08.001  0.339
2018 Klugman KP, Izadnegahdar R. Antibiotic prophylaxis-Preventing severe infections and saving lives in poor countries with very high mortality risk. Plos Medicine. 15: e1002594. PMID 29944649 DOI: 10.1371/Journal.Pmed.1002594  0.379
2018 Lattar SM, Wu X, Brophy J, Sakai F, Klugman KP, Vidal JE. A Mechanism of Unidirectional Transformation, Leading to Antibiotic Resistance, Occurs within Nasopharyngeal Pneumococcal Biofilm Consortia. Mbio. 9. PMID 29764945 DOI: 10.1128/Mbio.00561-18  0.376
2018 Lo SW, Gladstone RA, van Tonder AJ, Hawkins PA, Kwambana-Adams B, Cornick JE, Madhi SA, Nzenze SA, du Plessis M, Kandasamy R, Carter PE, Köseoglu Eser Ö, Ho PL, Elmdaghri N, Shakoor S, ... ... Klugman KP, et al. Global distribution of invasive serotype 35D post-PCV13 introduction. Journal of Clinical Microbiology. PMID 29720431 DOI: 10.1128/Jcm.00228-18  0.329
2018 Nelson KN, Grijalva CG, Chochua S, Hawkins PA, Gil AI, Lanata CF, Griffin MR, Edwards KM, Klugman KP, Vidal JE. Dynamics of Colonization ofStrains in Healthy Peruvian Children. Open Forum Infectious Diseases. 5: ofy039. PMID 29588913 DOI: 10.1093/Ofid/Ofy039  0.401
2017 Ginsburg AS, Klugman KP. Vaccination to reduce antimicrobial resistance. The Lancet. Global Health. 5: e1176-e1177. PMID 29128252 DOI: 10.1016/S2214-109X(17)30364-9  0.444
2017 Ndlangisa K, du Plessis M, Allam M, Wolter N, de Gouveia L, Klugman KP, Cohen C, Gladstone RA, von Gottberg A. Invasive disease caused simultaneously by dual serotypes of Streptococcus pneumoniae. Journal of Clinical Microbiology. PMID 29118167 DOI: 10.1128/Jcm.01149-17  0.427
2017 Wright MS, McCorrison J, Gomez AM, Beck E, Harkins D, Shankar J, Mounaud S, Segubre-Mercado E, Mojica AMR, Bacay B, Nzenze SA, Kimaro SZM, Adrian P, Klugman KP, Lucero MG, et al. Strain Level Streptococcus Colonization Patterns during the First Year of Life. Frontiers in Microbiology. 8: 1661. PMID 28932211 DOI: 10.3389/Fmicb.2017.01661  0.378
2017 Althouse BM, Hammitt LL, Grant L, Wagner BG, Reid R, Larzelere-Hinton F, Weatherholtz R, Klugman KP, Rodgers GL, O'Brien KL, Hu H. Identifying transmission routes of Streptococcus pneumoniae and sources of acquisitions in high transmission communities. Epidemiology and Infection. 1-9. PMID 28847317 DOI: 10.1017/S095026881700125X  0.375
2017 von Mollendorf C, Tempia S, von Gottberg A, Meiring S, Quan V, Feldman C, Cloete J, Madhi SA, O'Brien KL, Klugman KP, Whitney CG, Cohen C. Estimated severe pneumococcal disease cases and deaths before and after pneumococcal conjugate vaccine introduction in children younger than 5 years of age in South Africa. Plos One. 12: e0179905. PMID 28671978 DOI: 10.1371/Journal.Pone.0179905  0.422
2017 Wu X, Jacobs NT, Bozio C, Palm P, Lattar SM, Hanke CR, Watson DM, Sakai F, Levin BR, Klugman KP, Vidal JE. Competitive Dominance within Biofilm Consortia Regulate the Relative Distribution of Pneumococcal Nasopharyngeal Density. Applied and Environmental Microbiology. PMID 28576759 DOI: 10.1128/Aem.00953-17  0.363
2017 Klugman KP, Rodgers GL. PERCH in Perspective: What Can It Teach Us About Pneumonia Etiology in Children? Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 64: S185-S187. PMID 28575353 DOI: 10.1093/Cid/Cix075  0.352
2017 Nunes MC, Cutland CL, Jones S, Downs S, Weinberg A, Ortiz JR, Neuzil KM, Simões EAF, Klugman KP, Madhi SA. Efficacy of maternal influenza vaccination against all-cause lower respiratory tract infection hospitalizations in young infants: Results from a randomized controlled trial. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 28575286 DOI: 10.1093/Cid/Cix497  0.386
2017 Nzenze SA, Madhi SA, Shiri T, Klugman KP, de Gouveia L, Moore DP, Karstaedt AS, Tempia S, Nunes MC, von Gottberg A. Imputing direct and indirect vaccine effectiveness of childhood pneumococcal conjugate vaccine against invasive disease by surveying temporal changes in nasopharyngeal pneumococcal colonization. American Journal of Epidemiology. PMID 28482004 DOI: 10.1093/Aje/Kwx048  0.428
2017 Rodgers GL, Klugman KP. A new paradigm in pneumococcal conjugate vaccination: moving from individual to herd protection. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. PMID 28450197 DOI: 10.1016/J.Ijid.2017.04.015  0.362
2017 Madhi SA, Nunes M, Weinberg A, Kuwanda L, Hugo A, Jones S, van Niekerk N, Ortiz JR, Neuzil KM, Klugman KP, Simoes EA, Cutland CL. Contribution of serology assays in the evaluation of influenza virus infection rates and vaccine efficacy in pregnant women: Report from randomized controlled trials. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 28369198 DOI: 10.1093/Cid/Cix241  0.383
2017 Klugman KP, Rodgers GL. The future of paediatric pneumococcal conjugate vaccines. The Lancet. Respiratory Medicine. PMID 28359797 DOI: 10.1016/S2213-2600(17)30111-X  0.376
2017 Keddy KH, Musekiwa A, Sooka A, Karstaedt A, Nana T, Seetharam S, Nchabaleng M, Lekalakala R, Angulo FJ, Klugman KP. Clinical and microbiological features of invasive nontyphoidal Salmonella associated with HIV-infected patients, Gauteng Province, South Africa. Medicine. 96: e6448. PMID 28353576 DOI: 10.1097/Md.0000000000006448  0.321
2017 Cohen C, von Mollendorf C, de Gouveia L, Lengana S, Meiring S, Quan V, Nguweneza A, Moore DP, Reubenson G, Moshe M, Madhi SA, Eley B, Hallbauer U, Finlayson H, Varughese S, ... ... Klugman KP, et al. Effectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children: a case-control study. The Lancet. Global Health. PMID 28139443 DOI: 10.1016/S2214-109X(17)30043-8  0.316
2017 Cornick JE, Tastan Bishop Ö, Yalcin F, Kiran AM, Kumwenda B, Chaguza C, Govindpershad S, Ousmane S, Senghore M, du Plessis M, Pluschke G, Ebruke C, McGee L, Sigaùque B, Collard JM, ... ... Klugman KP, et al. The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1. Vaccine. PMID 28081968 DOI: 10.1016/J.Vaccine.2016.12.037  0.362
2016 Chochua S, D'Acremont V, Hanke C, Alfa D, Shak J, Kilowoko M, Kyungu E, Kaiser L, Genton B, Klugman KP, Vidal JE. Increased Nasopharyngeal Density and Concurrent Carriage of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Are Associated with Pneumonia in Febrile Children. Plos One. 11: e0167725. PMID 27907156 DOI: 10.1371/Journal.Pone.0167725  0.753
2016 Albrich WC, Pride MW, Madhi SA, Callahan J, Adrian PV, French R, van Niekerk N, Sebastian S, Souza V, Telles JN, Paranhos-Baccalà G, Jansen KU, Klugman KP. Multiplex urinary antigen detection for 13 Streptococcus pneumoniae serotypes improves diagnosis of pneumococcal pneumonia in South African HIV-infected adults. Journal of Clinical Microbiology. PMID 27847374 DOI: 10.1128/Jcm.01573-16  0.38
2016 Sobanjo-Ter Meulen A, Duclos P, McIntyre P, Lewis KD, Van Damme P, O'Brien KL, Klugman KP. Assessing the Evidence for Maternal Pertussis Immunization: A Report From the Bill & Melinda Gates Foundation Symposium on Pertussis Infant Disease Burden in Low- and Lower-Middle-Income Countries. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 63: S123-S133. PMID 27838664 DOI: 10.1093/Cid/Ciw530  0.336
2016 Chaguza C, Cornick JE, Harris SR, Andam CP, Bricio-Moreno L, Yang M, Yalcin F, Ousmane S, Govindpersad S, Senghore M, Ebruke C, Du Plessis M, Kiran AM, Pluschke G, Sigauque B, ... ... Klugman KP, et al. Understanding pneumococcal serotype 1 biology through population genomic analysis. Bmc Infectious Diseases. 16: 649. PMID 27821148 DOI: 10.1186/S12879-016-1987-Z  0.349
2016 Keddy KH, Sooka A, Smith AM, Musekiwa A, Tau NP, Klugman KP, Angulo FJ. Typhoid Fever in South Africa in an Endemic HIV Setting. Plos One. 11: e0164939. PMID 27780232 DOI: 10.1371/Journal.Pone.0164939  0.349
2016 Fan RR, Howard LM, Griffin MR, Edwards KM, Zhu Y, Williams JV, Vidal JE, Klugman KP, Gil AI, Lanata CF, Grijalva CG. Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009-2011. Emerging Infectious Diseases. 22: 1996-1999. PMID 27767919 DOI: 10.3201/Eid2211.160902  0.319
2016 Ndlangisa KM, du Plessis M, Allam M, Wolter N, Mohale T, de Gouveia L, Birkhead M, Klugman KP, von Gottberg A. Two cases of serotypeable and non-serotypeable variants of Streptococcus pneumoniae detected simultaneously during invasive disease. Bmc Microbiology. 16: 126. PMID 27342074 DOI: 10.1186/S12866-016-0745-0  0.355
2016 Keenan JD, Sahlu I, McGee L, Cevallos V, Vidal JE, Chochua S, Hawkins P, Gebre T, Tadesse Z, Emerson PM, Gaynor BD, Lietman TM, Klugman KP. Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma. Journal of the Pediatric Infectious Diseases Society. 5: 222-6. PMID 27199475 DOI: 10.1093/Jpids/Piu143  0.335
2016 Messaoudi M, Milenkov M, Albrich WC, van der Linden MP, Bénet T, Chou M, Sylla M, Barreto Costa P, Richard N, Klugman KP, Endtz HP, Paranhos-Baccalà G, Telles JN. The Relevance of a Novel Quantitative Assay to Detect up to 40 Major Streptococcus pneumoniae Serotypes Directly in Clinical Nasopharyngeal and Blood Specimens. Plos One. 11: e0151428. PMID 26986831 DOI: 10.1371/Journal.Pone.0151428  0.354
2016 Hanke CR, Grijalva CG, Chochua S, Pletz MW, Hornberg C, Edwards KM, Griffin MR, Verastegui H, Gil AI, Lanata CF, Klugman KP, Vidal JE. Bacterial Density, Serotype Distribution and Antibiotic Resistance of Pneumococcal Strains from the Nasopharynx of Peruvian Children Before and After Pneumococcal Conjugate Vaccine 7. The Pediatric Infectious Disease Journal. 35: 432-439. PMID 26974749 DOI: 10.1097/Inf.0000000000001030  0.474
2016 du Plessis M, Allam M, Tempia S, Wolter N, de Gouveia L, Mollendorf CV, Jolley KA, Mbelle N, Wadula J, Cornick JE, Everett DB, McGee L, Breiman RF, Gladstone RA, Bentley SD, ... Klugman KP, et al. Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989-2013. Journal of Clinical Microbiology. PMID 26962082 DOI: 10.1128/Jcm.00055-16  0.356
2016 Meiring S, Cohen C, Quan V, de Gouveia L, Feldman C, Karstaedt A, Klugman KP, Madhi SA, Rabie H, Sriruttan C, von Gottberg A. HIV Infection and the Epidemiology of Invasive Pneumococcal Disease (IPD) in South African Adults and Older Children Prior to the Introduction of a Pneumococcal Conjugate Vaccine (PCV). Plos One. 11: e0149104. PMID 26863135 DOI: 10.1371/Journal.Pone.0149104  0.422
2016 von Mollendorf C, Cohen C, Tempia S, Meiring S, de Gouveia L, Quan V, Lengana S, Karstaedt A, Dawood H, Seetharam S, Lekalakala R, Madhi SA, Klugman KP, von Gottberg A. Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003-2013. Emerging Infectious Diseases. 22: 261-70. PMID 26812214 DOI: 10.3201/Eid2202.150967  0.412
2016 Rodgers GL, Klugman KP. Surveillance of the impact of pneumococcal conjugate vaccines in developing countries. Human Vaccines & Immunotherapeutics. 12: 417-20. PMID 26309055 DOI: 10.1080/21645515.2015.1057671  0.418
2016 Nelson K, Grijalva CG, Chochua S, Hawkins P, Gil A, Lanata C, Griffin MR, Edwards K, Klugman K, Vidal J. Dynamics of Colonization and Recolonization of Streptococcus pneumoniae Strains in Healthy Peruvian Children Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.543  0.328
2015 Laxminarayan R, Matsoso P, Pant S, Brower C, Røttingen JA, Klugman K, Davies S. Access to effective antimicrobials: a worldwide challenge. Lancet (London, England). PMID 26603918 DOI: 10.1016/S0140-6736(15)00474-2  0.376
2015 Satzke C, Dunne EM, Porter BD, Klugman KP, Mulholland EK. The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage in Vaccine Evaluation Studies. Plos Medicine. 12: e1001903. PMID 26575033 DOI: 10.1371/Journal.Pmed.1001903  0.322
2015 Cohen C, Naidoo N, Meiring S, de Gouveia L, von Mollendorf C, Walaza S, Naicker P, Madhi SA, Feldman C, Klugman KP, Dawood H, von Gottberg A. Streptococcus pneumoniae Serotypes and Mortality in Adults and Adolescents in South Africa: Analysis of National Surveillance Data, 2003 - 2008. Plos One. 10: e0140185. PMID 26460800 DOI: 10.1371/Journal.Pone.0140185  0.376
2015 Sobanjo-Ter Meulen A, Abramson J, Mason E, Rees H, Schwalbe N, Bergquist S, Klugman KP. Path to impact: A report from the Bill and Melinda Gates Foundation convening on maternal immunization in resource-limited settings; Berlin - January 29-30, 2015. Vaccine. 33: 6388-95. PMID 26314626 DOI: 10.1016/J.Vaccine.2015.08.047  0.371
2015 Geno KA, Gilbert GL, Song JY, Skovsted IC, Klugman KP, Jones C, Konradsen HB, Nahm MH. Pneumococcal Capsules and Their Types: Past, Present, and Future. Clinical Microbiology Reviews. 28: 871-899. PMID 26085553 DOI: 10.1128/Cmr.00024-15  0.38
2015 Madhi SA, Izu A, Nunes MC, Violari A, Cotton MF, Jean-Philippe P, Klugman KP, von Gottberg A, van Niekerk N, Adrian PV. Longitudinal study on Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonization in HIV-infected and -uninfected infants vaccinated with pneumococcal conjugate vaccine. Vaccine. 33: 2662-9. PMID 25910923 DOI: 10.1016/j.vaccine.2015.04.024  0.341
2015 Sakai F, Chochua S, Satzke C, Dunne EM, Mulholland K, Klugman KP, Vidal JE. Single-plex quantitative assays for the detection and quantification of most pneumococcal serotypes. Plos One. 10: e0121064. PMID 25798884 DOI: 10.1371/Journal.Pone.0121064  0.378
2015 Memish ZA, Assiri A, Almasri M, Alhakeem RF, Turkestani A, Al Rabeeah AA, Akkad N, Yezli S, Klugman KP, O'Brien KL, van der Linden M, Gessner BD. Impact of the Hajj on pneumococcal transmission. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 21: 77.e11-8. PMID 25636939 DOI: 10.1016/J.Cmi.2014.07.005  0.433
2015 Weinberger DM, Klugman KP, Steiner CA, Simonsen L, Viboud C. Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data. Plos Medicine. 12: e1001776. PMID 25562317 DOI: 10.1371/Journal.Pmed.1001776  0.375
2015 Mina MJ, Klugman KP, Rosch JW, McCullers JA. Live attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear. The Journal of Infectious Diseases. 212: 195-201. PMID 25505300 DOI: 10.1093/Infdis/Jiu804  0.41
2015 Keenan JD, Klugman KP, McGee L, Vidal JE, Chochua S, Hawkins P, Cevallos V, Gebre T, Tadesse Z, Emerson PM, Jorgensen JH, Gaynor BD, Lietman TM. Evidence for clonal expansion after antibiotic selection pressure: pneumococcal multilocus sequence types before and after mass azithromycin treatments. The Journal of Infectious Diseases. 211: 988-94. PMID 25293366 DOI: 10.1093/Infdis/Jiu552  0.338
2015 von Mollendorf C, Cohen C, de Gouveia L, Naidoo N, Meiring S, Quan V, Lindani S, Moore DP, Reubenson G, Moshe M, Eley B, Hallbauer UM, Finlayson H, Madhi SA, Conklin L, ... ... Klugman KP, et al. Risk factors for invasive pneumococcal disease among children less than 5 years of age in a high HIV prevalence setting, South Africa, 2010 to 2012. The Pediatric Infectious Disease Journal. 34: 27-34. PMID 24992122 DOI: 10.1097/Inf.0000000000000484  0.353
2015 Chochua S, Sheets A, Keedy K, Jamieson B, Oldach D, Fernandes P, Das A, Klugman K, Vidal J. Detection of Pneumococcal Pneumonia in a Phase 3 Trial Comparing Oral Solithromycin Versus Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia in Adults Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.611  0.371
2015 Simões EAF, Cutland C, Carosone-Link P, Hugo A, Jones S, Madimabe R, Ortiz J, Neuzil K, Klugman K, Nunes M, Madhi S, Team M. Lack of Efficacy of Trivalent Influenza Vaccination of HIV-Negative Pregnant Women Against Adverse Fetal Outcomes: A Randomized Clinical Trial Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.1446  0.33
2015 Simões EAF, Cutland C, Carosone-Link P, Hugo A, Jones S, Klugman K, Nunes M, Madhi S, Team M. Impact of Trivalent Influenza Vaccination of Pregnant Women on Recurrent Respiratory Infections and Weight Gain in the First 6 Months of Life Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.1444  0.355
2014 Cremers AJ, Zomer AL, Gritzfeld JF, Ferwerda G, van Hijum SA, Ferreira DM, Shak JR, Klugman KP, Boekhorst J, Timmerman HM, de Jonge MI, Gordon SB, Hermans PW. The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition. Microbiome. 2: 44. PMID 25671106 DOI: 10.1186/2049-2618-2-44  0.754
2014 Nunes MC, Kuschner Z, Rabede Z, Cutland CL, Madimabe R, Kuwanda L, Klugman KP, Adrian PV, Madhi SA. Polyomaviruses-associated respiratory infections in HIV-infected and HIV-uninfected children. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 61: 571-8. PMID 25467863 DOI: 10.1016/J.Jcv.2014.10.013  0.319
2014 von Gottberg A, de Gouveia L, Tempia S, Quan V, Meiring S, von Mollendorf C, Madhi SA, Zell ER, Verani JR, O'Brien KL, Whitney CG, Klugman KP, Cohen C. Effects of vaccination on invasive pneumococcal disease in South Africa. The New England Journal of Medicine. 371: 1889-99. PMID 25386897 DOI: 10.1056/Nejmoa1401914  0.395
2014 Ndlangisa KM, du Plessis M, Wolter N, de Gouveia L, Klugman KP, von Gottberg A. Population snapshot of Streptococcus pneumoniae causing invasive disease in South Africa prior to introduction of pneumococcal conjugate vaccines. Plos One. 9: e107666. PMID 25233455 DOI: 10.1371/Journal.Pone.0107666  0.428
2014 Madhi SA, Cutland CL, Kuwanda L, Weinberg A, Hugo A, Jones S, Adrian PV, van Niekerk N, Treurnicht F, Ortiz JR, Venter M, Violari A, Neuzil KM, Simões EA, Klugman KP, et al. Influenza vaccination of pregnant women and protection of their infants. The New England Journal of Medicine. 371: 918-31. PMID 25184864 DOI: 10.1056/NEJMoa1401480  0.352
2014 Mina MJ, Klugman KP. The role of influenza in the severity and transmission of respiratory bacterial disease. The Lancet. Respiratory Medicine. 2: 750-63. PMID 25131494 DOI: 10.1016/S2213-2600(14)70131-6  0.39
2014 Albrich WC, Madhi SA, Adrian PV, van Niekerk N, Telles JN, Ebrahim N, Messaoudi M, Paranhos-Baccalà G, Giersdorf S, Vernet G, Mueller B, Klugman KP. Pneumococcal colonisation density: a new marker for disease severity in HIV-infected adults with pneumonia. Bmj Open. 4: e005953. PMID 25113557 DOI: 10.1136/Bmjopen-2014-005953  0.35
2014 Klugman KP. Herd protection induced by pneumococcal conjugate vaccine. The Lancet. Global Health. 2: e365-6. PMID 25103373 DOI: 10.1016/S2214-109X(14)70241-4  0.366
2014 Nzenze SA, Shiri T, Nunes MC, Klugman KP, Kahn K, Twine R, de Gouveia L, von Gottberg A, Madhi SA. Temporal association of infant immunisation with pneumococcal conjugate vaccine on the ecology of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonisation in a rural South African community. Vaccine. 32: 5520-30. PMID 25101982 DOI: 10.1016/J.Vaccine.2014.06.091  0.45
2014 Croucher NJ, Klugman KP. The emergence of bacterial "hopeful monsters". Mbio. 5: e01550-14. PMID 25073645 DOI: 10.1128/Mbio.01550-14  0.403
2014 Croucher NJ, Hanage WP, Harris SR, McGee L, van der Linden M, de Lencastre H, Sá-Leão R, Song JH, Ko KS, Beall B, Klugman KP, Parkhill J, Tomasz A, Kristinsson KG, Bentley SD. Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone. Bmc Biology. 12: 49. PMID 24957517 DOI: 10.1186/1741-7007-12-49  0.398
2014 Cohen C, von Mollendorf C, de Gouveia L, Naidoo N, Meiring S, Quan V, Nokeri V, Fortuin-de Smit M, Malope-Kgokong B, Moore D, Reubenson G, Moshe M, Madhi SA, Eley B, Hallbauer U, ... ... Klugman K, et al. Effectiveness of 7-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in HIV-infected and -uninfected children in south africa: a matched case-control study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 59: 808-18. PMID 24917657 DOI: 10.1093/Cid/Ciu431  0.416
2014 Croucher NJ, Chewapreecha C, Hanage WP, Harris SR, McGee L, van der Linden M, Song JH, Ko KS, de Lencastre H, Turner C, Yang F, Sá-Leão R, Beall B, Klugman KP, Parkhill J, et al. Evidence for soft selective sweeps in the evolution of pneumococcal multidrug resistance and vaccine escape. Genome Biology and Evolution. 6: 1589-602. PMID 24916661 DOI: 10.1093/Gbe/Evu120  0.44
2014 Shak JR, Cremers AJ, Gritzfeld JF, de Jonge MI, Hermans PW, Vidal JE, Klugman KP, Gordon SB. Impact of experimental human pneumococcal carriage on nasopharyngeal bacterial densities in healthy adults. Plos One. 9: e98829. PMID 24915552 DOI: 10.1371/Journal.Pone.0098829  0.761
2014 Wolter N, Tempia S, Cohen C, Madhi SA, Venter M, Moyes J, Walaza S, Malope-Kgokong B, Groome M, du Plessis M, Magomani V, Pretorius M, Hellferscee O, Dawood H, Kahn K, ... ... Klugman KP, et al. High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia. The Journal of Infectious Diseases. 210: 1649-57. PMID 24907383 DOI: 10.1093/Infdis/Jiu326  0.341
2014 Mina MJ, Klugman KP. Reply to "no clinical association of live attenuated influenza vaccine with nasal carriage of bacteria or acute otitis media": specific recommendations for future studies. Mbio. 5: e01173-14. PMID 24825014 DOI: 10.1128/Mbio.01173-14  0.444
2014 Talekar SJ, Chochua S, Nelson K, Klugman KP, Quave CL, Vidal JE. 220D-F2 from Rubus ulmifolius kills Streptococcus pneumoniae planktonic cells and pneumococcal biofilms. Plos One. 9: e97314. PMID 24823499 DOI: 10.1371/Journal.Pone.0097314  0.341
2014 Simonsen L, Taylor RJ, Schuck-Paim C, Lustig R, Haber M, Klugman KP. Effect of 13-valent pneumococcal conjugate vaccine on admissions to hospital 2 years after its introduction in the USA: a time series analysis. The Lancet. Respiratory Medicine. 2: 387-94. PMID 24815804 DOI: 10.1016/S2213-2600(14)70032-3  0.389
2014 Mina MJ, Burke RM, Klugman KP. Estimating the prevalence of coinfection with influenza virus and the atypical bacteria Bordetella pertussis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 33: 1585-9. PMID 24789653 DOI: 10.1007/S10096-014-2120-0  0.35
2014 von Mollendorf C, Cohen C, de Gouveia L, Quan V, Meiring S, Feldman C, Klugman KP, von Gottberg A. Factors associated with ceftriaxone nonsusceptibility of Streptococcus pneumoniae: analysis of South African national surveillance data, 2003 to 2010. Antimicrobial Agents and Chemotherapy. 58: 3293-305. PMID 24687499 DOI: 10.1128/Aac.02580-13  0.337
2014 Szu SC, Klugman KP, Hunt S. Re-examination of immune response and estimation of anti-Vi IgG protective threshold against typhoid fever-based on the efficacy trial of Vi conjugate in young children. Vaccine. 32: 2359-63. PMID 24630869 DOI: 10.1016/J.Vaccine.2014.02.050  0.341
2014 Grijalva CG, Griffin MR, Edwards KM, Williams JV, Gil AI, Verastegui H, Hartinger SM, Vidal JE, Klugman KP, Lanata CF. The role of influenza and parainfluenza infections in nasopharyngeal pneumococcal acquisition among young children. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 1369-76. PMID 24621951 DOI: 10.1093/Cid/Ciu148  0.359
2014 Vernet G, Mary C, Altmann DM, Doumbo O, Morpeth S, Bhutta ZA, Klugman KP. Surveillance for antimicrobial drug resistance in under-resourced countries. Emerging Infectious Diseases. 20: 434-41. PMID 24564906 DOI: 10.3201/Eid2003.121157  0.357
2014 Mina MJ, McCullers JA, Klugman KP. Live attenuated influenza vaccine enhances colonization of Streptococcus pneumoniae and Staphylococcus aureus in mice. Mbio. 5. PMID 24549845 DOI: 10.1128/Mbio.01040-13  0.446
2014 Ali A, Jafri RZ, Messonnier N, Tevi-Benissan C, Durrheim D, Eskola J, Fermon F, Klugman KP, Ramsay M, Sow S, Zhujun S, Bhutta Z, Abramson J. Global practices of meningococcal vaccine use and impact on invasive disease. Pathogens and Global Health. 108: 11-20. PMID 24548156 DOI: 10.1179/2047773214Y.0000000126  0.393
2014 Klugman KP. A tale of 2 pneumococcal vaccines. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 925-7. PMID 24532545 DOI: 10.1093/Cid/Ciu007  0.444
2014 Nunes MC, Kuschner Z, Rabede Z, Madimabe R, Van Niekerk N, Moloi J, Kuwanda L, Rossen JW, Klugman KP, Adrian PV, Madhi SA. Clinical epidemiology of bocavirus, rhinovirus, two polyomaviruses and four coronaviruses in HIV-infected and HIV-uninfected South African children. Plos One. 9: e86448. PMID 24498274 DOI: 10.1371/Journal.Pone.0086448  0.328
2014 Dong W, Chochua S, McGee L, Jackson D, Klugman KP, Vidal JE. Mutations within the rplD Gene of Linezolid-Nonsusceptible Streptococcus pneumoniae Strains Isolated in the United States. Antimicrobial Agents and Chemotherapy. 58: 2459-62. PMID 24492357 DOI: 10.1128/Aac.02630-13  0.323
2014 Klugman KP, Bentley SD, McGee L. Determinants of invasiveness beneath the capsule of the pneumococcus Journal of Infectious Diseases. 209: 321-322. PMID 24009157 DOI: 10.1093/Infdis/Jit483  0.412
2014 Wolter N, Cohen C, Tempia S, Madhi SA, Venter M, Moyes J, Walaza S, Malope Kgokong B, Groome M, du Plessis M, Pretorius M, Dawood H, Kahn K, Variava E, Klugman KP, et al. HIV and influenza virus infections are associated with increased blood pneumococcal load: a prospective, hospital-based observational study in South Africa, 2009-2011. The Journal of Infectious Diseases. 209: 56-65. PMID 23922370 DOI: 10.1093/Infdis/Jit427  0.335
2014 Grijalva CG, Griffin MR, Edwards KM, Williams JV, Gil AI, Verastegui H, Hartinger SM, Vidal JE, Klugman KP, Lanata CF. Cohort profile: The study of respiratory pathogens in Andean children. International Journal of Epidemiology. 43: 1021-30. PMID 23771719 DOI: 10.1093/Ije/Dyt065  0.403
2014 Madhi S, Cutland C, Jones S, Hugo A, Treurnicht F, Kuwanda L, Klugman K, Ortiz J, Neuzil K, Simoes EF, Venter M, Weinberg A, Nunes M. Randomized, placebo-controlled trial on safety and efficacy of inactivated influenza vaccination of pregnant women in preventing illness in their infants International Journal of Infectious Diseases. 21: 32. DOI: 10.1016/J.Ijid.2014.03.480  0.32
2014 Madhi S, Cutland C, Hugo A, Jones S, Kuwanda L, Dighero B, Treurnicht F, Klugman K, Venter M, Simoes E, Neuzil K, Ortiz J, Weinberg A, Nunes M. Efficacy and immunogenicity of inactivated influenza vaccine in pregnant women: A randomized, double-blind, placebo controlled trial International Journal of Infectious Diseases. 21: 430-431. DOI: 10.1016/J.Ijid.2014.03.1308  0.325
2013 Izadnegahdar R, Cohen AL, Klugman KP, Qazi SA. Childhood pneumonia in developing countries. The Lancet. Respiratory Medicine. 1: 574-84. PMID 24461618 DOI: 10.1016/S2213-2600(13)70075-4  0.374
2013 Satzke C, Turner P, Virolainen-Julkunen A, Adrian PV, Antonio M, Hare KM, Henao-Restrepo AM, Leach AJ, Klugman KP, Porter BD, Sá-Leão R, Scott JA, Nohynek H, O'Brien KL. Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group. Vaccine. 32: 165-79. PMID 24331112 DOI: 10.1016/J.Vaccine.2013.08.062  0.325
2013 Schuck-Paim C, Taylor R, Lindley D, Klugman KP, Simonsen L. Use of near-real-time medical claims data to generate timely vaccine coverage estimates in the US: the dynamics of PCV13 vaccine uptake. Vaccine. 31: 5983-8. PMID 24144470 DOI: 10.1016/J.Vaccine.2013.10.038  0.383
2013 Ginsburg AS, Tinkham L, Riley K, Kay NA, Klugman KP, Gill CJ. Antibiotic non-susceptibility among Streptococcus pneumoniae and Haemophilus influenzae isolates identified in African cohorts: A meta-analysis of three decades of published studies International Journal of Antimicrobial Agents. 42: 482-491. PMID 24139883 DOI: 10.1016/J.Ijantimicag.2013.08.012  0.469
2013 Shiri T, Nunes MC, Adrian PV, Van Niekerk N, Klugman KP, Madhi SA. Interrelationship of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus colonization within and between pneumococcal-vaccine naïve mother-child dyads. Bmc Infectious Diseases. 13: 483. PMID 24134472 DOI: 10.1186/1471-2334-13-483  0.434
2013 Shiri T, Auranen K, Nunes MC, Adrian PV, van Niekerk N, de Gouveia L, von Gottberg A, Klugman KP, Madhi SA. Dynamics of pneumococcal transmission in vaccine-naive children and their HIV-infected or HIV-uninfected mothers during the first 2 years of life. American Journal of Epidemiology. 178: 1629-37. PMID 24091888 DOI: 10.1093/Aje/Kwt200  0.375
2013 Nzenze SA, Shiri T, Nunes MC, Klugman KP, Kahn K, Twine R, de Gouveia L, von Gottberg A, Madhi SA. Temporal changes in pneumococcal colonization in a rural African community with high HIV prevalence following routine infant pneumococcal immunization. The Pediatric Infectious Disease Journal. 32: 1270-8. PMID 24061271 DOI: 10.1097/01.Inf.0000435805.25366.64  0.404
2013 Shak JR, Ludewick HP, Howery KE, Sakai F, Yi H, Harvey RM, Paton JC, Klugman KP, Vidal JE. Novel role for the Streptococcus pneumoniae toxin pneumolysin in the assembly of biofilms. Mbio. 4: e00655-13. PMID 24023386 DOI: 10.1128/Mbio.00655-13  0.762
2013 Jafri RZ, Ali A, Messonnier NE, Tevi-Benissan C, Durrheim D, Eskola J, Fermon F, Klugman KP, Ramsay M, Sow S, Zhujun S, Bhutta ZA, Abramson J. Global epidemiology of invasive meningococcal disease. Population Health Metrics. 11: 17. PMID 24016339 DOI: 10.1186/1478-7954-11-17  0.367
2013 Johri AK, Lata H, Yadav P, Dua M, Yang Y, Xu X, Homma A, Barocchi MA, Bottomley MJ, Saul A, Klugman KP, Black S. Epidemiology of Group B Streptococcus in developing countries. Vaccine. 31: D43-5. PMID 23973346 DOI: 10.1016/J.Vaccine.2013.05.094  0.328
2013 Mina MJ, Klugman KP, McCullers JA. Live attenuated influenza vaccine, but not pneumococcal conjugate vaccine, protects against increased density and duration of pneumococcal carriage after influenza infection in pneumococcal colonized mice. The Journal of Infectious Diseases. 208: 1281-5. PMID 23852122 DOI: 10.1093/Infdis/Jit317  0.427
2013 Sakai F, Talekar SJ, Klugman KP, Vidal JE. Expression of Streptococcus pneumoniae Virulence-Related Genes in the Nasopharynx of Healthy Children. Plos One. 8: e67147. PMID 23825636 DOI: 10.1371/Journal.Pone.0067147  0.314
2013 McGarry LJ, Gilmore KE, Rubin JL, Klugman KP, Strutton DR, Weinstein MC. Impact of 13-valent pneumococcal conjugate vaccine (PCV13) in a pandemic similar to the 2009 H1N1 in the United States. Bmc Infectious Diseases. 13: 229. PMID 23687999 DOI: 10.1186/1471-2334-13-229  0.386
2013 von Gottberg A, Cohen C, de Gouveia L, Meiring S, Quan V, Whitelaw A, Crowther-Gibson P, Madhi SA, Whitney CG, Klugman KP. Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003-2008. Vaccine. 31: 4200-8. PMID 23684826 DOI: 10.1016/J.Vaccine.2013.04.077  0.455
2013 Pletz MW, Michaylov N, Schumacher U, van der Linden M, Duesberg CB, Fuehner T, Klugman KP, Welte T, Makarewicz O. Antihypertensives suppress the emergence of fluoroquinolone-resistant mutants in pneumococci: an in vitro study. International Journal of Medical Microbiology : Ijmm. 303: 176-81. PMID 23545281 DOI: 10.1016/J.Ijmm.2013.02.014  0.321
2013 Vidal JE, Howery KE, Ludewick HP, Nava P, Klugman KP. Quorum-sensing systems LuxS/autoinducer 2 and Com regulate Streptococcus pneumoniae biofilms in a bioreactor with living cultures of human respiratory cells. Infection and Immunity. 81: 1341-53. PMID 23403556 DOI: 10.1128/Iai.01096-12  0.31
2013 Nunes MC, Shiri T, van Niekerk N, Cutland CL, Groome MJ, Koen A, von Gottberg A, de Gouveia L, Klugman KP, Adrian PV, Madhi SA. Acquisition of Streptococcus pneumoniae in pneumococcal conjugate vaccine-naïve South African children and their mothers. The Pediatric Infectious Disease Journal. 32: e192-205. PMID 23340555 DOI: 10.1097/Inf.0B013E31828683A3  0.335
2013 Shak JR, Vidal JE, Klugman KP. Influence of bacterial interactions on pneumococcal colonization of the nasopharynx. Trends in Microbiology. 21: 129-35. PMID 23273566 DOI: 10.1016/J.Tim.2012.11.005  0.768
2013 Wyres KL, Lambertsen LM, Croucher NJ, McGee L, Von Gottberg A, Liñares J, Jacobs MR, Kristinsson KG, Beall BW, Klugman KP, Parkhill J, Hakenbeck R, Bentley SD, Brueggemann AB. Pneumococcal capsular switching: A historical perspective Journal of Infectious Diseases. 207: 439-449. PMID 23175765 DOI: 10.1093/Infdis/Jis703  0.334
2013 Muhammad RD, Oza-Frank R, Zell E, Link-Gelles R, Narayan KM, Schaffner W, Thomas A, Lexau C, Bennett NM, Farley MM, Harrison LH, Reingold A, Hadler J, Beall B, Klugman KP, et al. Epidemiology of invasive pneumococcal disease among high-risk adults since the introduction of pneumococcal conjugate vaccine for children. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 56: e59-67. PMID 23155149 DOI: 10.1093/Cid/Cis971  0.4
2013 Chien YW, Vidal JE, Grijalva CG, Bozio C, Edwards KM, Williams JV, Griffin MR, Verastegui H, Hartinger SM, Gil AI, Lanata CF, Klugman KP. Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children. The Pediatric Infectious Disease Journal. 32: 72-7. PMID 22935873 DOI: 10.1097/Inf.0B013E318270D850  0.621
2012 Wyres KL, Lambertsen LM, Croucher NJ, McGee L, von Gottberg A, Liñares J, Jacobs MR, Kristinsson KG, Beall BW, Klugman KP, Parkhill J, Hakenbeck R, Bentley SD, Brueggemann AB. The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success Genome Biology. 13. PMID 23158461 DOI: 10.1186/Gb-2012-13-11-R103  0.388
2012 Trück J, Lazarus R, Jonsdottir I, Klugman KP, Pollard AJ. Pneumococcal polysaccharide vaccine efficacy and routine use of conjugate vaccines in infants: there is no need for a vaccine program in older adults at present. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 55: 1577-9; author reply. PMID 22903769 DOI: 10.1093/Cid/Cis700  0.368
2012 Grabenstein JD, Klugman KP. A century of pneumococcal vaccination research in humans Clinical Microbiology and Infection. 18: 15-24. PMID 22882735 DOI: 10.1111/J.1469-0691.2012.03943.X  0.435
2012 Strutton DR, Farkouh RA, Rubin JL, McGarry LJ, Loiacono PM, Klugman KP, Pelton SI, Gilmore KE, Weinstein MC. Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data. Bmc Infectious Diseases. 12: 175. PMID 22863074 DOI: 10.1186/1471-2334-12-175  0.374
2012 Crowther-Gibson P, Cohen C, Klugman KP, de Gouveia L, von Gottberg A. Risk factors for multidrug-resistant invasive pneumococcal disease in South Africa, a setting with high HIV prevalence, in the prevaccine era from 2003 to 2008. Antimicrobial Agents and Chemotherapy. 56: 5088-95. PMID 22802256 DOI: 10.1128/Aac.06463-11  0.424
2012 Bottomley MJ, Serruto D, Sáfadi MA, Klugman KP. Future challenges in the elimination of bacterial meningitis. Vaccine. 30: B78-86. PMID 22607903 DOI: 10.1016/J.Vaccine.2011.12.099  0.46
2012 Sinha A, Kim S, Ginsberg G, Franklin H, Kohberger R, Strutton D, Madhi SA, Griffiths UK, Klugman KP. Economic burden of acute lower respiratory tract infection in South African children. Paediatrics and International Child Health. 32: 65-73. PMID 22595212 DOI: 10.1179/2046905512Y.0000000010  0.309
2012 du Plessis M, Moodley C, Mothibeli KM, Fali A, Klugman KP, von Gottberg A. Population snapshot of invasive serogroup B meningococci in South Africa from 2005 to 2008. Journal of Clinical Microbiology. 50: 2577-84. PMID 22593593 DOI: 10.1128/Jcm.00401-12  0.354
2012 Song JH, Dagan R, Klugman KP, Fritzell B. The relationship between pneumococcal serotypes and antibiotic resistance. Vaccine. 30: 2728-37. PMID 22330126 DOI: 10.1016/J.Vaccine.2012.01.091  0.46
2012 Zhou H, Haber M, Ray S, Farley MM, Panozzo CA, Klugman KP. Invasive pneumococcal pneumonia and respiratory virus co-infections. Emerging Infectious Diseases. 18: 294-7. PMID 22305270 DOI: 10.3201/Eid1802.102025  0.347
2012 Chien YW, Levin BR, Klugman KP. The anticipated severity of a "1918-like" influenza pandemic in contemporary populations: the contribution of antibacterial interventions. Plos One. 7: e29219. PMID 22291887 DOI: 10.1371/Journal.Pone.0029219  0.656
2012 Omer SB, Bednarczyk R, Madhi SA, Klugman KP. Benefits to mother and child of influenza vaccination during pregnancy. Human Vaccines & Immunotherapeutics. 8: 130-7. PMID 22251998 DOI: 10.4161/Hv.8.1.18601  0.401
2012 Reed C, Madhi SA, Klugman KP, Kuwanda L, Ortiz JR, Finelli L, Fry AM. Development of the Respiratory Index of Severity in Children (RISC) score among young children with respiratory infections in South Africa. Plos One. 7: e27793. PMID 22238570 DOI: 10.1371/Journal.Pone.0027793  0.355
2012 Soeters HM, von Gottberg A, Cohen C, Quan V, Klugman KP. Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease. Antimicrobial Agents and Chemotherapy. 56: 1602-5. PMID 22232291 DOI: 10.1128/Aac.05813-11  0.414
2012 von Gottberg A, Cohen C, Whitelaw A, Chhagan M, Flannery B, Cohen AL, de Gouveia L, Plessis Md, Madhi SA, Klugman KP. Invasive disease due to Haemophilus influenzae serotype b ten years after routine vaccination, South Africa, 2003-2009. Vaccine. 30: 565-71. PMID 22119925 DOI: 10.1016/J.Vaccine.2011.11.066  0.432
2012 Plessis M, Smith AM, Klugman KP. Detection of Penicillin Resistance in Streptococcus pneumoniae by a Seminested PCR Strategy. Methods in Molecular Medicine. 48: 65-75. PMID 21374406 DOI: 10.1385/1-59259-077-2:65  0.401
2011 Albrich WC, Madhi SA, Adrian PV, van Niekerk N, Mareletsi T, Cutland C, Wong M, Khoosal M, Karstaedt A, Zhao P, Deatly A, Sidhu M, Jansen KU, Klugman KP. Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 54: 601-9. PMID 22156852 DOI: 10.1093/Cid/Cir859  0.307
2011 Nunes MC, von Gottberg A, de Gouveia L, Cohen C, Kuwanda L, Karstaedt AS, Klugman KP, Madhi SA. Persistent high burden of invasive pneumococcal disease in South African HIV-infected adults in the era of an antiretroviral treatment program. Plos One. 6: e27929. PMID 22140487 DOI: 10.1371/Journal.Pone.0027929  0.314
2011 Laxminarayan R, Klugman KP. Communicating trends in resistance using a drug resistance index. Bmj Open. 1: e000135. PMID 22102636 DOI: 10.1136/Bmjopen-2011-000135  0.374
2011 Nair H, Brooks WA, Katz M, Roca A, Berkley JA, Madhi SA, Simmerman JM, Gordon A, Sato M, Howie S, Krishnan A, Ope M, Lindblade KA, Carosone-Link P, Lucero M, ... ... Klugman KP, et al. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. Lancet. 378: 1917-30. PMID 22078723 DOI: 10.1016/S0140-6736(11)61051-9  0.359
2011 Rodgers GL, Klugman KP. The future of pneumococcal disease prevention. Vaccine. 29: C43-8. PMID 21896352 DOI: 10.1016/J.Vaccine.2011.07.047  0.415
2011 Klugman KP. Contribution of vaccines to our understanding of pneumococcal disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2790-8. PMID 21893542 DOI: 10.1098/Rstb.2011.0032  0.49
2011 Hicks LA, Chien YW, Taylor TH, Haber M, Klugman KP. Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996-2003. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 53: 631-9. PMID 21890767 DOI: 10.1093/Cid/Cir443  0.633
2011 Rudolf D, Michaylov N, van der Linden M, Hoy L, Klugman KP, Welte T, Pletz MW. International pneumococcal clones match or exceed the fitness of other strains despite the accumulation of antibiotic resistance. Antimicrobial Agents and Chemotherapy. 55: 4915-7. PMID 21825290 DOI: 10.1128/Aac.00250-11  0.408
2011 Vidal JE, Ludewick HP, Kunkel RM, Zähner D, Klugman KP. The LuxS-dependent quorum-sensing system regulates early biofilm formation by Streptococcus pneumoniae strain D39. Infection and Immunity. 79: 4050-60. PMID 21825061 DOI: 10.1128/Iai.05186-11  0.326
2011 Nyasulu P, Cohen C, De Gouveia L, Feldman C, Klugman KP, von Gottberg A. Increased risk of death in human immunodeficiency virus-infected children with pneumococcal meningitis in South Africa, 2003-2005. The Pediatric Infectious Disease Journal. 30: 1075-80. PMID 21799459 DOI: 10.1097/Inf.0B013E31822Cca05  0.382
2011 Madhi SA, Violari A, Klugman KP, Lin G, McIntyre JA, von Gottberg A, Jean-Philippe P, Cotton MF, Adrian P. Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization Vaccine. 29: 6994-7001. PMID 21787822 DOI: 10.1016/J.Vaccine.2011.07.035  0.369
2011 Omer SB, Goodman D, Steinhoff MC, Rochat R, Klugman KP, Stoll BJ, Ramakrishnan U. Maternal influenza immunization and reduced likelihood of prematurity and small for gestational age births: a retrospective cohort study. Plos Medicine. 8: e1000441. PMID 21655318 DOI: 10.1371/Journal.Pmed.1000441  0.351
2011 Grundmann H, Klugman KP, Walsh T, Ramon-Pardo P, Sigauque B, Khan W, Laxminarayan R, Heddini A, Stelling J. A framework for global surveillance of antibiotic resistance. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 14: 79-87. PMID 21482177 DOI: 10.1016/J.Drup.2011.02.007  0.341
2011 Vernet G, Saha S, Satzke C, Burgess DH, Alderson M, Maisonneuve JF, Beall BW, Steinhoff MC, Klugman KP. Laboratory-based diagnosis of pneumococcal pneumonia: state of the art and unmet needs. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 17: 1-13. PMID 21457174 DOI: 10.1111/J.1469-0691.2011.03496.X  0.405
2011 Rouphael N, Steyn S, Bangert M, Sampson JS, Adrian P, Madhi SA, Klugman KP, Ades EW. Use of 2 pneumococcal common protein real-time polymerase chain reaction assays in healthy children colonized with Streptococcus pneumoniae Diagnostic Microbiology and Infectious Disease. 70: 452-454. PMID 21397430 DOI: 10.1016/J.Diagmicrobio.2010.09.006  0.302
2011 Klugman KP, Madhi SA, Adegbola RA, Cutts F, Greenwood B, Hausdorff WP. Timing of serotype 1 pneumococcal disease suggests the need for evaluation of a booster dose. Vaccine. 29: 3372-3373. PMID 21396901 DOI: 10.1016/J.Vaccine.2011.02.089  0.358
2011 Croucher NJ, Harris SR, Fraser C, Quail MA, Burton J, van der Linden M, McGee L, von Gottberg A, Song JH, Ko KS, Pichon B, Baker S, Parry CM, Lambertsen LM, Shahinas D, ... ... Klugman KP, et al. Rapid pneumococcal evolution in response to clinical interventions. Science (New York, N.Y.). 331: 430-4. PMID 21273480 DOI: 10.1126/Science.1198545  0.435
2011 Simonsen L, Taylor RJ, Young-Xu Y, Haber M, May L, Klugman KP. Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United States. Mbio. 2: e00309-10. PMID 21264063 DOI: 10.1128/Mbio.00309-10  0.396
2011 Nunes MC, von Gottberg A, de Gouveia L, Cohen C, Moore DP, Klugman KP, Madhi SA. The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis. Aids (London, England). 25: 453-62. PMID 21178754 DOI: 10.1097/Qad.0B013E328341B7F1  0.379
2011 Mothibeli KM, Plessis Md, Gottberg Av, Murphy E, Hoiseth SK, Zlotnick G, Klugman KP. Distribution of factor H binding protein beyond serogroup B: variation among five serogroups of invasive Neisseria meningitidis in South Africa. Vaccine. 29: 2187-2192. PMID 21144918 DOI: 10.1016/J.Vaccine.2010.11.072  0.358
2011 Dagan R, Bhutta ZA, de Quadros CA, Garau J, Klugman KP, Khuri-Bulos N, Levine O, Saha SK, Sow S, Were F, Yang Y. The remaining challenge of pneumonia: the leading killer of children. The Pediatric Infectious Disease Journal. 30: 1-2. PMID 21076365 DOI: 10.1097/Inf.0B013E3182005389  0.317
2011 Pletz MW, van der Linden M, von Baum H, Duesberg CB, Klugman KP, Welte T. Low prevalence of fluoroquinolone resistant strains and resistance precursor strains in Streptococcus pneumoniae from patients with community-acquired pneumonia despite high fluoroquinolone usage. International Journal of Medical Microbiology : Ijmm. 301: 53-7. PMID 20692869 DOI: 10.1016/J.Ijmm.2010.05.004  0.427
2011 Nzenze S, Klugman K, Madhi S. The potential impact of the 13-valent conjugate pneumococcal vaccine on antibiotic resistance in pneumococci Southern African Journal of Epidemiology and Infection. 26: 253-258. DOI: 10.1080/10158782.2011.11441462  0.468
2011 Klugman KP, Hayden Smith SW, Koornhof HJ. Evidence that prevention of carriage by pneumococcal capsular vaccines may be the mechanism of protection from pneumococcal pneumonia Southern African Journal of Epidemiology and Infection. 26: 221-224. DOI: 10.1080/10158782.2011.11441456  0.403
2010 Moore DP, Klugman KP, Madhi SA. Role of Streptococcus pneumoniae in hospitalization for acute community-acquired pneumonia associated with culture-confirmed Mycobacterium tuberculosis in children: a pneumococcal conjugate vaccine probe study. The Pediatric Infectious Disease Journal. 29: 1099-04. PMID 21155174 DOI: 10.1097/Inf.0B013E3181Eaefff  0.42
2010 Dagan R, de Quadros CA, Garau J, Klugman KP, Khuri-Bulos N, Levine O, Sow S, Yang Y. Marking November 12, 2010 - World Pneumonia Day: where are we, where are vaccines? Human Vaccines. 6: 922-5. PMID 21045539 DOI: 10.4161/Hv.6.11.13599  0.332
2010 Chien YW, Klugman KP, Morens DM. Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic. The Journal of Infectious Diseases. 202: 1639-48. PMID 21028954 DOI: 10.1086/657144  0.644
2010 Pletz MW, Welte T, Klugman KP. The paradox in pneumococcal serotypes: Highly invasive does not mean highly lethal European Respiratory Journal. 36: 712-713. PMID 20889457 DOI: 10.1183/09031936.00041210  0.436
2010 Rubin JL, McGarry LJ, Strutton DR, Klugman KP, Pelton SI, Gilmore KE, Weinstein MC. Public health and economic impact of the 13-valent pneumococcal conjugate vaccine (PCV13) in the United States. Vaccine. 28: 7634-43. PMID 20883739 DOI: 10.1016/J.Vaccine.2010.09.049  0.404
2010 Fali A, Plessis Md, Wolter N, von Gottberg A, Klugman KP. Single report of β-lactam resistance in an invasive Haemophilus influenzae isolate from South Africa mediated by mutations in penicillin-binding protein 3, 2003-2008 International Journal of Antimicrobial Agents. 36: 480-482. PMID 20846827 DOI: 10.1016/J.Ijantimicag.2010.07.017  0.342
2010 Ramakrishnan M, Moïsi JC, Etame MM, Klugman KP, Feris JM, Levine OS. Invasive infections and sickle-cell disease - Authors' reply The Lancet Infectious Diseases. 10: 593-594. PMID 20797638 DOI: 10.1016/S1473-3099(10)70181-X  0.315
2010 Weinberger DM, Harboe ZB, Sanders EA, Ndiritu M, Klugman KP, Rückinger S, Dagan R, Adegbola R, Cutts F, Johnson HL, O'Brien KL, Scott JA, Lipsitch M. Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 51: 692-9. PMID 20715907 DOI: 10.1086/655828  0.338
2010 du Plessis M, de Gouveia L, Skosana H, Thomas J, Blumberg L, Klugman KP, von Gottberg A. Invasive Neisseria meningitidis with decreased susceptibility to fluoroquinolones in South Africa, 2009. The Journal of Antimicrobial Chemotherapy. 65: 2258-60. PMID 20688769 DOI: 10.1093/Jac/Dkq291  0.318
2010 Madhi SA, Schoub B, Klugman KP. Interaction between influenza virus and Streptococcus pneumoniae in severe pneumonia. Expert Review of Respiratory Medicine. 2: 663-72. PMID 20477301 DOI: 10.1586/17476348.2.5.663  0.303
2010 Madhi SA, Schoub B, Klugman KP. Interaction between influenza virus and Streptococcus pneumoniae in severe pneumonia. Expert Review of Respiratory Medicine. 2: 663-72. PMID 20477301 DOI: 10.1586/17476348.2.5.663  0.303
2010 Ramakrishnan M, Moïsi JC, Klugman KP, Iglesias JM, Grant LR, Mpoudi-Etame M, Levine OS. Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis. The Lancet. Infectious Diseases. 10: 329-37. PMID 20417415 DOI: 10.1016/S1473-3099(10)70055-4  0.334
2010 Feldman C, Brink AJ, von Gottberg A, Wolter N, de Gouveia L, Perovic O, Klugman KP. Antimicrobial susceptibility of pneumococcal isolates causing bacteraemic pneumococcal pneumonia: analysis using current breakpoints and fluoroquinolone pharmacodynamics. International Journal of Antimicrobial Agents. 36: 95-7. PMID 20378315 DOI: 10.1016/J.Ijantimicag.2010.02.021  0.42
2010 Rubin JL, McGarry LJ, Klugman KP, Strutton DR, Gilmore KE, Weinstein MC. Public health and economic impact of vaccination with 7-valent pneumococcal vaccine (PCV7) in the context of the annual influenza epidemic and a severe influenza pandemic. Bmc Infectious Diseases. 10: 14. PMID 20092638 DOI: 10.1186/1471-2334-10-14  0.376
2010 Mothibeli KM, du Plessis M, von Gottberg A, de Gouveia L, Adrian P, Madhi SA, Klugman KP. An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South Africa. Journal of Clinical Microbiology. 48: 184-91. PMID 19889905 DOI: 10.1128/Jcm.01011-09  0.394
2010 Feldman C, Cockeran R, Steel H, Wolter N, Gouveia Ld, Gottberg Av, Klugman KP, Leanord A, Inverarity D, Mitchell TJ, Anderson R. Effects of Clarithromycin, at Sub-MIC Concentrations, on the Growth of Macrolide-Resistant Streptococcus pneumoniae Chest. 138: 7-8. DOI: 10.1378/Chest.9504  0.337
2010 Klugman K. Pneumococcal infection and colonization in children and its impact on pneumococcal disease in adults International Journal of Infectious Diseases. 14: e313. DOI: 10.1016/J.Ijid.2010.02.2182  0.357
2010 Berkelman RL, Klugman KP. Emergence and Resurgence of Bacterial Infectious Diseases Topley and Wilson's Microbiology and Microbial Infections. DOI: 10.1002/9780470688618.Taw0015  0.303
2009 Chien YW, Klugman KP, Morens DM. Bacterial pathogens and death during the 1918 influenza pandemic. The New England Journal of Medicine. 361: 2582-3. PMID 20032332 DOI: 10.1056/Nejmc0908216  0.594
2009 Klugman KP, Dagan R. Pneumonia vaccines for all who need them Human Vaccines. 5: 779-780. PMID 19901523 DOI: 10.4161/Hv.5.11.10100  0.397
2009 Levine OS, Klugman KP. Editorial: Breathing new life into pneumonia epidemiology. American Journal of Epidemiology. 170: 1067-8. PMID 19808633 DOI: 10.1093/Aje/Kwp316  0.369
2009 Ray GT, Pelton SI, Klugman KP, Strutton DR, Moore MR. Cost-effectiveness of pneumococcal conjugate vaccine: an update after 7 years of use in the United States. Vaccine. 27: 6483-94. PMID 19720366 DOI: 10.1016/J.Vaccine.2009.08.045  0.378
2009 Klugman KP, Chien YW, Madhi SA. Pneumococcal pneumonia and influenza: a deadly combination. Vaccine. 27: C9-C14. PMID 19683658 DOI: 10.1016/J.Vaccine.2009.06.007  0.658
2009 Whitney AM, Coulson GB, von Gottberg A, Block C, Keller N, Mayer LW, Messonnier NE, Klugman KP. Genotypic comparison of invasive Neisseria meningitidis serogroup Y isolates from the United States, South Africa, and Israel, isolated from 1999 through 2002. Journal of Clinical Microbiology. 47: 2787-93. PMID 19571028 DOI: 10.1128/Jcm.00091-09  0.328
2009 Murphy E, Andrew L, Lee KL, Dilts DA, Nunez L, Fink PS, Ambrose K, Borrow R, Findlow J, Taha MK, Deghmane AE, Kriz P, Musilek M, Kalmusova J, Caugant DA, ... ... Klugman KP, et al. Sequence diversity of the factor H binding protein vaccine candidate in epidemiological relevant strains of serogroup B neisseria meningitidis Journal of Infectious Diseases. 200: 379-389. PMID 19534597 DOI: 10.1086/600141  0.353
2009 Weinstein MP, Klugman KP, Jones RN. Rationale for Revised Penicillin Susceptibility Breakpoints versus Streptococcus pneumoniae: Coping with Antimicrobial Susceptibility in an Era of Resistance Clinical Infectious Diseases. 48: 1596-1600. PMID 19400744 DOI: 10.1086/598975  0.389
2009 Klugman KP. The significance of serotype replacement for pneumococcal disease and antibiotic resistance Advances in Experimental Medicine and Biology. 634: 121-128. PMID 19280854 DOI: 10.1007/978-0-387-79838-7_11  0.391
2009 Madhi SA, Klugman KP, Kuwanda L, Cutland C, Käyhty H, Adrian P. Quantitative and qualitative anamnestic immune responses to pneumococcal conjugate vaccine in HIV-infected and HIV-uninfected children 5 years after vaccination Journal of Infectious Diseases. 199: 1168-1176. PMID 19265481 DOI: 10.1086/597388  0.388
2009 Wolter N, du Plessis M, von Gottberg A, de Gouveia L, Klugman KP. Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa. Journal of Clinical Microbiology. 47: 1319-24. PMID 19261799 DOI: 10.1128/Jcm.02280-08  0.408
2009 Grant GB, Campbell H, Dowell SF, Graham SM, Klugman KP, Mulholland EK, Steinhoff M, Weber MW, Qazi S. Recommendations for treatment of childhood non-severe pneumonia. The Lancet. Infectious Diseases. 9: 185-96. PMID 19246022 DOI: 10.1016/S1473-3099(09)70044-1  0.368
2009 Klugman KP, Astley CM, Lipsitch M. Time from illness onset to death, 1918 influenza and pneumococcal pneumonia Emerging Infectious Diseases. 15: 346-347. PMID 19193293 DOI: 10.3201/Eid1502.081208  0.346
2009 McGee L, Biek D, Ge Y, Klugman M, Du Plessis M, Smith AM, Beall B, Whitney CG, Klugman KP. In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 53: 552-556. PMID 19015339 DOI: 10.1128/Aac.01324-08  0.421
2009 File TM, Monte SV, Schentag JJ, Paladino JA, Klugman KP, Lavin B, Yu VL, Singer ME, Adelman MH. A disease model descriptive of progression between chronic obstructive pulmonary disease exacerbations and community-acquired pneumonia: roles for underlying lung disease and the pharmacokinetics/pharmacodynamics of the antibiotic. International Journal of Antimicrobial Agents. 33: 58-64. PMID 18835762 DOI: 10.1016/J.Ijantimicag.2008.07.019  0.315
2008 Dagan R, Klugman KP. Impact of conjugate pneumococcal vaccines on antibiotic resistance The Lancet Infectious Diseases. 8: 785-795. PMID 19022193 DOI: 10.1016/S1473-3099(08)70281-0  0.436
2008 Klugman KP, Madhi SA, Albrich WC. Novel approaches to the identification of Streptococcus pneumoniae as the cause of community-acquired pneumonia Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 47. PMID 18986290 DOI: 10.1086/591405  0.37
2008 Duesberg CB, Malhotra-Kumar S, Goossens H, McGee L, Klugman KP, Welte T, Pletz MWR. Interspecies recombination occurs frequently in quinolone resistance-determining regions of clinical isolates of Streptococcus pyogenes Antimicrobial Agents and Chemotherapy. 52: 4191-4193. PMID 18765693 DOI: 10.1128/Aac.00518-08  0.38
2008 du Plessis M, von Gottberg A, Madhi SA, Hattingh O, de Gouveia L, Klugman KP. Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South Africa. International Journal of Antimicrobial Agents. 32: S66-70. PMID 18723328 DOI: 10.1016/J.Ijantimicag.2008.06.002  0.416
2008 Yang F, Xu XG, Yang MJ, Zhang YY, Klugman KP, McGee L. Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China International Journal of Antimicrobial Agents. 32: 386-391. PMID 18723327 DOI: 10.1016/J.Ijantimicag.2008.05.004  0.412
2008 du Plessis M, von Gottberg A, Cohen C, de Gouveia L, Klugman KP. Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005. Journal of Clinical Microbiology. 46: 3208-14. PMID 18650361 DOI: 10.1128/Jcm.00221-08  0.399
2008 Klugman KP, Walsh AL, Phiri A, Molyneux EM. Mortality in penicillin-resistant pneumococcal meningitis Pediatric Infectious Disease Journal. 27: 671-672. PMID 18520964 DOI: 10.1097/Inf.0B013E31817709Cf  0.362
2008 von Gottberg A, Klugman KP, Cohen C, Wolter N, de Gouveia L, du Plessis M, Mpembe R, Quan V, Whitelaw A, Hoffmann R, Govender N, Meiring S, Smith AM, Schrag S. Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance study. Lancet (London, England). 371: 1108-13. PMID 18359074 DOI: 10.1016/S0140-6736(08)60350-5  0.444
2008 Wolter N, von Gottberg A, du Plessis M, de Gouveia L, Klugman KP. Molecular basis and clonal nature of increasing pneumococcal macrolide resistance in South Africa, 2000-2005. International Journal of Antimicrobial Agents. 32: 62-7. PMID 18339522 DOI: 10.1016/J.Ijantimicag.2008.01.013  0.431
2008 Pemba L, Charalambous S, von Gottberg A, Magadla B, Moloi V, Seabi O, Wasas A, Klugman KP, Chaisson RE, Fielding K, Churchyard GJ, Grant AD. Impact of cotrimoxazole on non-susceptibility to antibiotics in Streptococcus pneumoniae carriage isolates among HIV-infected mineworkers in South Africa. The Journal of Infection. 56: 171-8. PMID 18262281 DOI: 10.1016/J.Jinf.2007.12.003  0.384
2007 Klugman KP. Risk factors for antibiotic resistance in Streptococcus pneumoniae South African Medical Journal. 97: 1129-1132. PMID 18250923 DOI: 10.7196/Samj.256  0.489
2007 Yu VL, Hansen DS, Ko WC, Sagnimeni A, Klugman KP, von Gottberg A, Goossens H, Wagener MM, Benedi VJ. Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections. Emerging Infectious Diseases. 13: 986-93. PMID 18214169 DOI: 10.3201/Eid1307.070187  0.357
2007 Wolter N, Smith AM, Farrell DJ, Northwood JB, Douthwaite S, Klugman KP. Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. Antimicrobial Agents and Chemotherapy. 52: 435-40. PMID 18056269 DOI: 10.1128/Aac.01074-07  0.337
2007 Madhi SA, Adrian P, Kuwanda L, Cutland C, Albrich WC, Klugman KP. Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae - and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization - in HIV-infected and HIV-uninfected children Journal of Infectious Diseases. 196: 1662-1666. PMID 18008250 DOI: 10.1086/522164  0.414
2007 Geddes AM, Klugman KP, Rolinson GN. Introduction: historical perspective and development of amoxicillin/clavulanate International Journal of Antimicrobial Agents. 30: 109-112. PMID 17900874 DOI: 10.1016/J.Ijantimicag.2007.07.015  0.38
2007 Madhi SA, Ludewick H, Kuwanda L, van Niekerk N, Cutland C, Klugman KP. Seasonality, incidence, and repeat human metapneumovirus lower respiratory tract infections in an area with a high prevalence of human immunodeficiency virus type-1 infection. The Pediatric Infectious Disease Journal. 26: 693-9. PMID 17848880 DOI: 10.1097/Inf.0B013E3180621192  0.34
2007 Albrich WC, Madhi SA, Lafond KE, Klugman KP. Herd immunity after pneumococcal conjugate vaccination Lancet. 370: 218-219. PMID 17658389 DOI: 10.1016/S0140-6736(07)61119-2  0.356
2007 Schentag JJ, Klugman KP, Yu VL, Adelman MH, Wilton GJ, Chiou CC, Patel M, Lavin B, Paladino JA. Streptococcus pneumoniae bacteraemia: pharmacodynamic correlations with outcome and macrolide resistance--a controlled study. International Journal of Antimicrobial Agents. 30: 264-9. PMID 17587549 DOI: 10.1016/J.Ijantimicag.2007.04.013  0.315
2007 Alanee SR, McGee L, Jackson D, Chiou CC, Feldman C, Morris AJ, Ortqvist A, Rello J, Luna CM, Baddour LM, Ip M, Yu VL, Klugman KP. Association of serotypes of Streptococcus pneumoniae with disease severity and outcome in adults: an international study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 45: 46-51. PMID 17554699 DOI: 10.1086/518538  0.401
2007 Coulson GB, von Gottberg A, du Plessis M, Smith AM, de Gouveia L, Klugman KP. Meningococcal disease in South Africa, 1999-2002. Emerging Infectious Diseases. 13: 273-81. PMID 17479891 DOI: 10.3201/Eid1302.051553  0.322
2007 Klugman KP, Madhi SA. Pneumococcal vaccines and flu preparedness [2] Science. 316: 49-50. PMID 17412937 DOI: 10.1126/Science.316.5821.49C  0.419
2007 Siber GR, Chang I, Baker S, Fernsten P, O'Brien KL, Santosham M, Klugman KP, Madhi SA, Paradiso P, Kohberger R. Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies. Vaccine. 25: 3816-26. PMID 17368878 DOI: 10.1016/J.Vaccine.2007.01.119  0.348
2007 Klugman KP. Clinical impact of antibiotic resistance in respiratory tract infections International Journal of Antimicrobial Agents. 29. PMID 17307654 DOI: 10.1016/S0924-8579(07)70004-3  0.402
2007 Farrell DJ, Klugman KP, Pichichero M. Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States Pediatric Infectious Disease Journal. 26: 123-128. PMID 17259873 DOI: 10.1097/01.Inf.0000253059.84602.C3  0.426
2007 Anderson R, Steel HC, Cockeran R, Smith AM, von Gottberg A, de Gouveia L, Brink A, Klugman KP, Mitchell TJ, Feldman C. Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae. The Journal of Antimicrobial Chemotherapy. 59: 224-9. PMID 17218449 DOI: 10.1093/Jac/Dkl479  0.332
2007 Wolter N, Smith AM, Low DE, Klugman KP. High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 51: 1092-1095. PMID 17210764 DOI: 10.1128/Aac.01153-06  0.35
2007 Klugman KP, Madhi SA, Feldman C. HIV and pneumococcal disease Current Opinion in Infectious Diseases. 20: 11-15. PMID 17197876 DOI: 10.1097/Qco.0B013E328012C5F1  0.361
2007 Rozen DE, McGee L, Levin BR, Klugman KP. Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy. 51: 412-6. PMID 17116668 DOI: 10.1128/Aac.01161-06  0.373
2007 Madhi SA, Adrian P, Kuwanda L, Jassat W, Jones S, Little T, Soininen A, Cutland C, Klugman KP. Long-term immunogenicity and efficacy of a 9-valent conjugate pneumococcal vaccine in human immunodeficient virus infected and non-infected children in the absence of a booster dose of vaccine Vaccine. 25: 2451-2457. PMID 17023095 DOI: 10.1016/J.Vaccine.2006.09.019  0.412
2007 Madhi SA, Klugman KP. World Health Organisation definition of "radiologically-confirmed pneumonia" may under-estimate the true public health value of conjugate pneumococcal vaccines Vaccine. 25: 2413-2419. PMID 17005301 DOI: 10.1016/J.Vaccine.2006.09.010  0.396
2007 Vaughan DJ, Tillotson GS, Klugman KP. Streptococcus pneumoniae: Review of factors relevant to development and management of fluoroquinolone resistance in a nursing home setting Infectious Diseases in Clinical Practice. 15: 92-99. DOI: 10.1097/01.Idc.0000239722.78078.17  0.451
2006 Tillotson GS, Carroll J, Klugman KP. Antimicrobial resistance-fluoroquinolones and the tiger's tail Journal of Chemotherapy. 18: 328-330. PMID 17129847 DOI: 10.1179/Joc.2006.18.3.328  0.353
2006 von Gottberg A, de Gouveia L, Madhi SA, du Plessis M, Quan V, Soma K, Huebner R, Flannery B, Schuchat A, Klugman K. Impact of conjugate Haemophilus influenzae type b (Hib) vaccine introduction in South Africa. Bulletin of the World Health Organization. 84: 811-8. PMID 17128361 DOI: 10.2471/Blt.06.030361  0.393
2006 Pletz MW, Fugit RV, McGee L, Glasheen JJ, Keller DL, Welte T, Klugman KP. Fluoroquinolone-resistant Streptococcus pneumoniae. Emerging Infectious Diseases. 12: 1462-3. PMID 17073107 DOI: 10.3201/Eid1209.051400  0.366
2006 Klugman KP, Yu VL. No impact of penicillin resistance on mortality. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 43: 261; author reply 26. PMID 16779757 DOI: 10.1086/505305  0.333
2006 Levine OS, O'Brien KL, Knoll M, Adegbola RA, Black S, Cherian T, Dagan R, Goldblatt D, Grange A, Greenwood B, Hennessy T, Klugman KP, Madhi SA, Mulholland K, Nohynek H, et al. Pneumococcal vaccination in developing countries. Lancet. 367: 1880-2. PMID 16765742 DOI: 10.1016/S0140-6736(06)68703-5  0.424
2006 Madhi SA, Kuwanda L, Cutland C, Klugman KP. Five-year cohort study of hospitalization for respiratory syncytial virus associated lower respiratory tract infection in African children Journal of Clinical Virology. 36: 215-221. PMID 16678480 DOI: 10.1016/J.Jcv.2006.03.010  0.338
2006 Madhi SA, Ludewick H, Kuwanda L, Niekerk Nv, Cutland C, Little T, Klugman KP. Pneumococcal coinfection with human metapneumovirus. The Journal of Infectious Diseases. 193: 1236-43. PMID 16586360 DOI: 10.1086/503053  0.328
2006 Pletz MW, Shergill AP, McGee L, Beall B, Whitney CG, Klugman KP. Prevalence of first-step mutants among levofloxacin-susceptible invasive isolates of Streptococcus pneumoniae in the United States. Antimicrobial Agents and Chemotherapy. 50: 1561-3. PMID 16569885 DOI: 10.1128/Aac.50.4.1561-1563.2006  0.335
2006 Pletz MW, McGee L, Van Beneden CA, Petit S, Bardsley M, Barlow M, Klugman KP. Fluoroquinolone resistance in invasive Streptococcus pyogenes isolates due to spontaneous mutation and horizontal gene transfer. Antimicrobial Agents and Chemotherapy. 50: 943-8. PMID 16495255 DOI: 10.1128/Aac.50.3.943-948.2006  0.359
2006 Klugman KP, Levin BR. One enzyme inactivates two antibiotics. Nature Medicine. 12: 19-20. PMID 16397547 DOI: 10.1038/Nm0106-19  0.303
2006 Madhi SA, Kohler M, Kuwanda L, Cutland C, Klugman KP. Usefulness of C-reactive protein to define pneumococcal conjugate vaccine efficacy in the prevention of pneumonia. The Pediatric Infectious Disease Journal. 25: 30-6. PMID 16395099 DOI: 10.1097/01.Inf.0000195787.99199.4A  0.4
2006 Wolter N, Smith AM, Farrell DJ, Klugman KP. Heterogeneous macrolide resistance and gene conversion in the pneumococcus Antimicrobial Agents and Chemotherapy. 50: 359-361. PMID 16377711 DOI: 10.1128/Aac.50.1.359-361.2006  0.373
2006 Klugman KP. Fluoroquinolone treatment of pneumococcal infections The Southern African Journal of Epidemiology and Infection. 21: 34-35. DOI: 10.1080/10158782.2006.11441259  0.328
2005 Smith AM, Klugman KP. Amino acid mutations essential to production of an altered PBP 2X: Conferring high-level β-lactam resistance in a clinical isolate of Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 49: 4622-4627. PMID 16251304 DOI: 10.1128/Aac.49.11.4622-4627.2005  0.349
2005 Okeke IN, Klugman KP, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, Pablos-Mendez A, Laxminarayan R. Antimicrobial resistance in developing countries. Part II: strategies for containment. The Lancet. Infectious Diseases. 5: 568-80. PMID 16122680 DOI: 10.1016/S1473-3099(05)70217-6  0.4
2005 Madhi SA, Kuwanda L, Saarinen L, Cutland C, Mothupi R, Käyhty H, Klugman KP. Immunogenicity and effectiveness of Haemophilus influenzae type b conjugate vaccine in HIV infected and uninfected African children. Vaccine. 23: 5517-25. PMID 16107294 DOI: 10.1016/J.Vaccine.2005.07.038  0.34
2005 Wolter N, Smith AM, Farrell DJ, Schaffner W, Moore M, Whitney CG, Jorgensen JH, Klugman KP. Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus. Antimicrobial Agents and Chemotherapy. 49: 3554-7. PMID 16048983 DOI: 10.1128/Aac.49.8.3554-3557.2005  0.365
2005 Okeke IN, Laxminarayan R, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, Pablos-Mendez A, Klugman KP. Antimicrobial resistance in developing countries. Part I: recent trends and current status. The Lancet. Infectious Diseases. 5: 481-93. PMID 16048717 DOI: 10.1016/S1473-3099(05)70189-4  0.392
2005 Feikin DR, Klugman KP, Facklam RR, Zell ER, Schuchat A, Whitney CG. Increased prevalence of pediatric pneumococcal serotypes in elderly adults Clinical Infectious Diseases. 41: 481-487. PMID 16028155 DOI: 10.1086/432015  0.394
2005 Farrell DJ, Jenkins SG, Brown SD, Patel M, Lavin BS, Klugman KP. Emergence and spread of Streptococcus pneumoniae with erm(B) and mef(A) resistance. Emerging Infectious Diseases. 11: 851-8. PMID 15963279 DOI: 10.3201/Eid1106.050222  0.416
2005 Klugman KP, Lonks JR. Hidden epidemic of macrolide-resistant pneumococci Emerging Infectious Diseases. 11: 802-807. PMID 15963272 DOI: 10.3201/Eid1106.050147  0.396
2005 Madhi SA, Kuwanda L, Cutland C, Holm A, Käyhty H, Klugman KP. Quantitative and qualitative antibody response to pneumococcal conjugate vaccine among African human immunodeficiency virus-infected and uninfected children. The Pediatric Infectious Disease Journal. 24: 410-6. PMID 15876939 DOI: 10.1097/01.Inf.0000160942.84169.14  0.391
2005 Klugman KP, Welsh KJ. Nasopharyngeal carriage of pneumococcal pediatric serotypes: A risk for acute and recurrent otitis media in children and for invasive disease in susceptible adults Journal of Infectious Diseases. 191: 1790-1792. PMID 15871109 DOI: 10.1086/429924  0.346
2005 Smith AM, Feldman C, Massidda O, McCarthy K, Ndiweni D, Klugman KP. Altered PBP 2A and its role in the development of penicillin, cefotaxime, and ceftriaxone resistance in a clinical isolate of Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy. 49: 2002-7. PMID 15855525 DOI: 10.1128/Aac.49.5.2002-2007.2005  0.4
2005 Madhi SA, Kuwanda L, Cutland C, Klugman KP. The impact of a 9-valent pneumococcal conjugate vaccine on the public health burden of pneumonia in HIV-infected and -uninfected children Clinical Infectious Diseases. 40: 1511-1518. PMID 15844075 DOI: 10.1086/429828  0.444
2005 Trzciński K, MacNeil A, Klugman KP, Lipsitch M. Capsule homology does not increase the frequency of transformation of linked penicillin binding proteins PBP 1a and PBP 2x in Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 49: 1591-1592. PMID 15793147 DOI: 10.1128/Aac.49.4.1591-1592.2005  0.304
2005 Madhi SA, Heera JR, Kuwanda L, Klugman KP. Use of procalcitonin and C-reactive protein to evaluate vaccine efficacy against pneumonia Plos Medicine. 2: 0147-0151. PMID 15736995 DOI: 10.1371/Journal.Pmed.0020038  0.434
2005 Hausdorff WP, Feikin DR, Klugman KP. Epidemiological differences among pneumococcal serotypes Lancet Infectious Diseases. 5: 83-93. PMID 15680778 DOI: 10.1016/S1473-3099(05)01280-6  0.439
2005 Pletz MW, McGee L, Beall B, Whitney CG, Klugman KP. Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States. Antimicrobial Agents and Chemotherapy. 49: 779-80. PMID 15673766 DOI: 10.1128/Aac.49.2.779-780.2005  0.373
2005 Pletz MWR, McGee L, Burkhardt O, Lode H, Klugman KP. Ciprofloxacin treatment failure in a patient with resistant Streptococcus pneumoniae infection following prior ciprofloxacin therapy European Journal of Clinical Microbiology & Infectious Diseases. 24: 58-60. PMID 15592904 DOI: 10.1007/S10096-004-1254-X  0.381
2005 Huebner RE, Nicol M, Mothupi R, Käyhty H, Mbelle N, Khomo E, Klugman KP. Dose response of CRM197 and tetanus toxoid-conjugated Haemophilus influenzae type b vaccines. Vaccine. 23: 802-6. PMID 15542205 DOI: 10.1016/J.Vaccine.2004.06.052  0.376
2005 Klugman KP, Low DE, Metlay J, Pechere JC, Weiss K. Community-acquired pneumonia: new management strategies for evolving pathogens and antimicrobial susceptibilities. International Journal of Antimicrobial Agents. 24: 411-22. PMID 15519470 DOI: 10.1016/J.Ijantimicag.2004.08.006  0.4
2005 Frean J, Arntzen L, Klugman K. Susceptibility of Bacillus anthracis to moxifloxacin The Southern African Journal of Epidemiology and Infection. 20: 119-120. DOI: 10.1080/10158782.2005.11441247  0.305
2004 Ball AP, Bartlett JG, Craig WA, Drusano GL, Felmingham D, Garau JA, Klugman KP, Low DE, Mandell LA, Rubinstein E, Tillotson GS. Future trends in antimicrobial chemotherapy: expert opinion on the 43rd ICAAC. Journal of Chemotherapy (Florence, Italy). 16: 419-36. PMID 15565907 DOI: 10.1179/Joc.2004.16.5.419  0.347
2004 Ambrose PG, Bast D, Doern GV, Iannini PB, Jones RN, Klugman KP, Low DE. Fluoroquinolone-resistant Streptococcus pneumoniae, an emerging but unrecognized public health concern: is it time to resight the goalposts? Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 39: 1554-6; author reply. PMID 15546106 DOI: 10.1086/425508  0.331
2004 Klugman KP, Madhi SA. Oral antibiotics for the treatment of severe pneumonia in children Lancet. 364: 1104-1105. PMID 15451204 DOI: 10.1016/S0140-6736(04)17116-X  0.338
2004 Martin M, Casellas JM, Madhi SA, Urquhart TJ, Delport SD, Ferrero F, Chamany S, Dayan GH, Rose CE, Levine OS, Klugman KP, Feikin DR. Impact of haemophilus influenzae type b conjugate vaccine in South Africa and Argentina. The Pediatric Infectious Disease Journal. 23: 842-7. PMID 15361724 DOI: 10.1097/01.Inf.0000137575.82874.0C  0.41
2004 Klugman KP. Vaccination: A novel approach to reduce antibiotic resistance Clinical Infectious Diseases. 39: 649-651. PMID 15356777 DOI: 10.1086/422655  0.439
2004 Pletz MW, McGee L, Jorgensen J, Beall B, Facklam RR, Whitney CG, Klugman KP. Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine. Antimicrobial Agents and Chemotherapy. 48: 3491-7. PMID 15328116 DOI: 10.1128/Aac.48.9.3491-3497.2004  0.461
2004 Schrag SJ, McGee L, Whitney CG, Beall B, Craig AS, Choate ME, Jorgensen JH, Facklam RR, Klugman KP. Emergence of Streptococcus pneumoniae with very-high-level resistance to penicillin. Antimicrobial Agents and Chemotherapy. 48: 3016-23. PMID 15273115 DOI: 10.1128/Aac.48.8.3016-3023.2004  0.451
2004 Madhi SA, Klugman KP. A role for Streptococcus pneumoniae in virus-associated pneumonia Nature Medicine. 10: 811-813. PMID 15247911 DOI: 10.1038/Nm1077  0.415
2004 Huebner RE, Mbelle N, Forrest B, Madore DV, Klugman KP. Long-term antibody levels and booster responses in South African children immunized with nonavalent pneumococcal conjugate vaccine. Vaccine. 22: 2696-700. PMID 15246599 DOI: 10.1016/J.Vaccine.2003.03.001  0.401
2004 Paterson DL, Ko WC, Von Gottberg A, Mohapatra S, Casellas JM, Goossens H, Mulazimoglu L, Trenholme G, Klugman KP, Bonomo RA, Rice LB, Wagener MM, McCormack JG, Yu VL. Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 39: 31-7. PMID 15206050 DOI: 10.1086/420816  0.352
2004 Whitney CG, Klugman KP. Vaccines as tools against resistance: The example of pneumococcal conjugate vaccine Seminars in Pediatric Infectious Diseases. 15: 86-93. PMID 15185191 DOI: 10.1053/J.Spid.2004.01.011  0.49
2004 Baddour LM, Yu VL, Klugman KP, Feldman C, Ortqvist A, Rello J, Morris AJ, Luna CM, Snydman DR, Wen CK, Chedid MBF, Hui DS, Andremont A, Chiou CCC, Mosquera R, et al. Combination Antibiotic Therapy Lowers Mortality among Severely III Patients with Pneumococcal Bacteremia American Journal of Respiratory and Critical Care Medicine. 170: 440-444. PMID 15184200 DOI: 10.1164/Rccm.200311-1578Oc  0.332
2004 Buie KA, Klugman KP, von Gottberg A, Perovic O, Karstaedt A, Crewe-Brown HH, Madhi SA, Feldman C. Gender as a risk factor for both antibiotic resistance and infection with pediatric serogroups/serotypes, in HIV-infected and -uninfected adults with pneumococcal bacteremia. The Journal of Infectious Diseases. 189: 1996-2000. PMID 15143465 DOI: 10.1086/386548  0.391
2004 File TM, Garau J, Blasi F, Chidiac C, Klugman K, Lode H, Lonks JR, Mandell L, Ramirez J, Yu V. Guidelines for empiric antimicrobial prescribing in community-acquired pneumonia. Chest. 125: 1888-901. PMID 15136404 DOI: 10.1378/Chest.125.5.1888  0.364
2004 Jódar L, Butler J, Carlone G, Dagan R, Goldblatt D, Käyhty H, Klugman K, Plikaytis B, Siber G, Kohberger R, Chang I, Cherian T. Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants. Vaccine. 21: 3265-72. PMID 12804857 DOI: 10.1016/S0264-410X(03)00230-5  0.377
2003 von Gottberg A, Ludewick H, Bamber S, Govind C, Sturm AW, Klugman KP. Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in a South African child in a tuberculosis treatment facility. The Pediatric Infectious Disease Journal. 22: 1020-1. PMID 14628774 DOI: 10.1097/01.Inf.0000095430.29265.7F  0.358
2003 Klugman KP, Madhi SA, Huebner RE, Kohberger R, Mbelle N, Pierce N. A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. The New England Journal of Medicine. 349: 1341-8. PMID 14523142 DOI: 10.1056/Nejmoa035060  0.435
2003 Huebner RE, Wasas AD, Klugman KP. Antibiotic prescribing practices for common childhood illnesses in South Africa South African Medical Journal. 93: 505-508. PMID 12939920 DOI: 10.7196/Samj.2245  0.313
2003 Frean J, Klugman KP, Arntzen L, Bukofzer S. Susceptibility of Yersinia pestis to novel and conventional antimicrobial agents Journal of Antimicrobial Chemotherapy. 52: 294-296. PMID 12865386 DOI: 10.1093/Jac/Dkg363  0.311
2003 Frean J, Klugman KP, Arntzen L, Bukofzer S. Susceptibility of Bacillus anthracis to eleven antimicrobial agents including novel fluoroquinolones and a ketolide Journal of Antimicrobial Chemotherapy. 52: 297-299. PMID 12865385 DOI: 10.1093/Jac/Dkg364  0.387
2003 Yu VL, Chiou CC, Feldman C, Ortqvist A, Rello J, Morris AJ, Baddour LM, Luna CM, Snydman DR, Ip M, Ko WC, Chedid MB, Andremont A, Klugman KP. An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: 230-7. PMID 12856216 DOI: 10.1086/377534  0.402
2003 Klugman KP. Implications for antimicrobial prescribing of strategies based on bacterial eradication International Journal of Infectious Diseases. 7. PMID 12839705 DOI: 10.1016/S1201-9712(03)90068-3  0.397
2003 Feikin DR, Davis M, Nwanyanwu OC, Kazembe PN, Barat LM, Wasas A, Bloland PB, Ziba C, Capper T, Huebner RE, Schwartz B, Klugman KP, Dowell SF. Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children. The Pediatric Infectious Disease Journal. 22: 564-7. PMID 12828156  0.33
2003 Huebner RE, Wasas AD, Hockman M, Klugman KP. Bacterial aetiology of non-resolving otitis media in South African children Journal of Laryngology and Otology. 117: 169-172. PMID 12648369 DOI: 10.1258/002221503321192430  0.428
2003 Pelton SI, Dagan R, Gaines BM, Klugman KP, Laufer D, O'Brien K, Schmitt HJ. Pneumococcal conjugate vaccines: proceedings from an interactive symposium at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Vaccine. 21: 1562-71. PMID 12639477 DOI: 10.1016/S0264-410X(02)00681-3  0.453
2003 Klugman KP. The role of clonality in the global spread of fluoroquinolone-resistant bacteria Clinical Infectious Diseases. 36: 783-785. PMID 12627363 DOI: 10.1086/367935  0.43
2003 Smith AM, Klugman KP. Site-specific mutagenesis analysis of PBP 1A from a penicillin-cephalosporin-resistant pneumococcal isolate Antimicrobial Agents and Chemotherapy. 47: 387-389. PMID 12499220 DOI: 10.1128/Aac.47.1.387-389.2003  0.323
2003 Wasas AD, Huebner RE, Hockman M, Klugman KP. Correlation between erythromycin and azithromycin resistance in Streptococcus pneumoniae. South African Medical Journal. 93: 283. DOI: 10.7196/Samj.2139  0.374
2003 Feikin DR, Davis M, Nwanyanwu OC, Kazembe PN, Barat LM, Wasas A, Bloland PB, Ziba C, Capper T, Huebner RE, Schwartz B, Klugman KP, Dowell SF. Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children The Pediatric Infectious Disease Journal. 22: 564-567. DOI: 10.1097/01.Inf.0000069787.33960.D6  0.44
2002 Klugman KP. The successful clone: The vector of dissemination of resistance in Streptococcus pneumoniae Journal of Antimicrobial Chemotherapy. 50: 1-5. PMID 12556427 DOI: 10.1093/Jac/Dkf500  0.382
2002 Huebner RE, Mbelle N, Forrest B, Madore DV, Klugman KP. Immunogenicity after one, two or three doses and impact on the antibody response to coadministered antigens of a nonavalent pneumococcal conjugate vaccine in infants of Soweto, South Africa. Pediatric Infectious Disease Journal. 21: 1004-1007. PMID 12442020 DOI: 10.1097/00006454-200211000-00006  0.335
2002 Felmingham D, Feldman C, Hryniewicz W, Klugman K, Kohno S, Low DE, Mendes C, Rodloff AC. Surveillance of resistance in bacteria causing community‐acquired respiratory tract infections Clinical Microbiology and Infection. 8: 12-42. PMID 12427206 DOI: 10.1046/J.1469-0691.8.S.2.5.X  0.441
2002 Madhi SA, Cutland C, Ismail K, O'Reilly C, Mancha A, Klugman KP. Ineffectiveness of trimethoprim-sulfamethoxazole prophylaxis and the importance of bacterial and viral coinfections in African children with Pneumocystis carinii pneumonia. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 35: 1120-6. PMID 12384847 DOI: 10.1086/343049  0.366
2002 Mandell LA, Peterson LR, Wise R, Hooper D, Low DE, Schaad UB, Klugman KP, Courvalin P. The battle against emerging antibiotic resistance: should fluoroquinolones be used to treat children? Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 35: 721-7. PMID 12203170 DOI: 10.1086/341900  0.419
2002 Feikin DR, Klugman KP. Historical changes in pneumococcal serogroup distribution: Implications for the era of pneumococcal conjugate vaccines Clinical Infectious Diseases. 35: 547-555. PMID 12173128 DOI: 10.1086/341896  0.425
2002 Madhi SA, Cumin E, Klugman KP. Defining the potential impact of conjugate bacterial polysaccharide-protein vaccines in reducing the burden of pneumonia in human immunodeficiency virus type 1-infected and -uninfected children Pediatric Infectious Disease Journal. 21: 393-399. PMID 12150175 DOI: 10.1097/00006454-200205000-00009  0.375
2002 Du Plessis M, Bingen E, Klugman KP. Analysis of penicillin-binding protein genes of clinical isolates of Streptococcus pneumoniae with reduced susceptibility to amoxicillin Antimicrobial Agents and Chemotherapy. 46: 2349-2357. PMID 12121904 DOI: 10.1128/Aac.46.8.2349-2357.2002  0.389
2002 Madhi SA, Petersen K, Khoosal M, Huebner RE, Mbelle N, Mothupi R, Saloojee H, Crewe-Brown H, Klugman KP. Reduced effectiveness of Haemophilus influenzae type b conjugate vaccine in children with a high prevalence of human immunodeficiency virus type 1 infection. The Pediatric Infectious Disease Journal. 21: 315-21. PMID 12075763 DOI: 10.1097/00006454-200204000-00011  0.421
2002 Madhi SA, Ramasamy N, Bessellar TG, Saloojee H, Klugman KP. Lower respiratory tract infections associated with influenza A and B viruses in an area with a high prevalence of pediatric human immunodeficiency type 1 infection. The Pediatric Infectious Disease Journal. 21: 291-7. PMID 12075759 DOI: 10.1097/00006454-200204000-00007  0.359
2002 Nicol M, Huebner R, Mothupi R, Käyhty H, Mbelle N, Khomo E, Klugman KP. Haemophilus influenzae type b conjugate vaccine diluted tenfold in diphtheria-tetanus-whole cell pertussis vaccine: a randomized trial. The Pediatric Infectious Disease Journal. 21: 138-41. PMID 11840081 DOI: 10.1097/00006454-200202000-00010  0.398
2002 Sáez-Llorens X, McCoig C, Feris JM, Vargas SL, Klugman KP, Hussey GD, Frenck RW, Falleiros-Carvalho LH, Arguedas AG, Bradley J, Arrieta AC, Wald ER, Pancorbo S, McCracken GH, Marques SR, et al. Quinolone treatment for pediatric bacterial meningitis: a comparative study of trovafloxacin and ceftriaxone with or without vancomycin. The Pediatric Infectious Disease Journal. 21: 14-22. PMID 11791092 DOI: 10.1097/00006454-200201000-00004  0.364
2002 McGee L, Goldsmith CE, Klugman KP. Flouroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones Journal of Antimicrobial Chemotherapy. 49: 173-176. PMID 11751784 DOI: 10.1093/Jac/49.1.173  0.39
2002 Ball P, Baquero F, Cars O, File T, Garau J, Klugman K, Low DE, Rubinstein E, Wise R. Antibiotic therapy of community respiratory tract infections: strategies for optimal outcomes and minimized resistance emergence Journal of Antimicrobial Chemotherapy. 49: 31-40. PMID 11751764 DOI: 10.1093/Jac/49.1.31  0.406
2001 Klugman KP, Feldman C. Streptococcus pneumoniae respiratory tract infections Current Opinion in Infectious Diseases. 14: 173-179. PMID 11979129 DOI: 10.1097/00019048-200202000-00007  0.414
2001 Klugman KP. Efficacy of pneumococcal conjugate vaccines and their effect on carriage and antimicrobial resistance Lancet Infectious Diseases. 1: 85-91. PMID 11871480 DOI: 10.1016/S1473-3099(01)00063-9  0.455
2001 Madhi SA, Madhi A, Petersen K, Khoosal M, Klugman KP. Impact of human immunodeficiency virus type 1 infection on the epidemiology and outcome of bacterial meningitis in South African children International Journal of Infectious Diseases. 5: 119-125. PMID 11724667 DOI: 10.1016/S1201-9712(01)90085-2  0.373
2001 Smith AM, Botha RF, Koornhof HJ, Klugman KP. Emergence of a pneumococcal clone with cephalosporin resistance and penicillin susceptibility Antimicrobial Agents and Chemotherapy. 45: 2648-2650. PMID 11502545 DOI: 10.1128/Aac.45.9.2648-2650.2001  0.38
2001 Klugman KP. Antibiotic selection of multiply resistant pneumococci Clinical Infectious Diseases. 33: 489-491. PMID 11462185 DOI: 10.1086/322736  0.405
2001 Smith AM, Klugman KP. Alterations in MurM, a cell wall muropeptide branching enzyme, increase high-level penicillin and cephalosporin resistance in Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 45: 2393-2396. PMID 11451707 DOI: 10.1128/Aac.45.8.2393-2396.2001  0.326
2001 McGee L, McDougal L, Zhou J, Spratt BG, Tenover FC, George R, Hakenbeck R, Hryniewicz W, Lefévre JC, Tomasz A, Klugman KP. Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. Journal of Clinical Microbiology. 39: 2565-71. PMID 11427569 DOI: 10.1128/Jcm.39.7.2565-2571.2001  0.382
2001 Paterson DL, Ko WC, Von Gottberg A, Casellas JM, Mulazimoglu L, Klugman KP, Bonomo RA, Rice LB, McCormack JG, Yu VL. Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory. Journal of Clinical Microbiology. 39: 2206-12. PMID 11376058 DOI: 10.1128/Jcm.39.6.2206-2212.2001  0.37
2001 McGee L, Wang H, Wasas A, Huebner R, Chen M, Klugman KP. Prevalence of serotypes and molecular epidemiology of Streptococcus pneumoniae strains isolated from children in Beijing, China: identification of two novel multiply-resistant clones. Microbial Drug Resistance (Larchmont, N.Y.). 7: 55-63. PMID 11310804 DOI: 10.1089/107662901750152800  0.45
2001 McGee L, Klugman KP, Wasas A, Capper T, Brink A. Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa. Antimicrobial Agents and Chemotherapy. 45: 1595-8. PMID 11302838 DOI: 10.1128/Aac.45.5.1595-1598.2001  0.37
2001 Madhi SA, Venter M, Madhi A, Petersen K, Klugman KP. Differing manifestations of respiratory syncytial virus-associated severe lower respiratory tract infections in human immunodeficiency virus type 1-infected and uninfected children Pediatric Infectious Disease Journal. 20: 164-170. PMID 11224836 DOI: 10.1097/00006454-200102000-00010  0.336
2001 Dagan R, Klugman KP, Craig WA, Baquero F. Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy Journal of Antimicrobial Chemotherapy. 47: 129-140. PMID 11157895 DOI: 10.1093/Jac/47.2.129  0.378
2001 Huebner RE, Dagan R, Porath N, Wasas AD, Klugman KP. Lack of utility of serotyping multiple colonies for detection of simultaneous nasopharyngeal carriage of different pneumococcal serotypes. The Pediatric Infectious Disease Journal. 19: 1017-20. PMID 11055610 DOI: 10.1097/00006454-200010000-00019  0.31
2001 Klugman K, Tam JS. Pneumococcal conjugate vaccines in Asia and the Pacific, Singapore, 9–11 October 2000. Report of an Asia Pacific Advisory Board Meeting1For the Asia Pacific Advisory Board (see Appendix for faculty listing).1 Vaccine. 19: 4579-4587. DOI: 10.1016/S0264-410X(01)00256-0  0.361
2000 Smego RA, Genovese G, Klugman KP. Rationale for a hospital-based pneumococcal vaccine trial for HIV-seropositive South Africans International Journal of Infectious Diseases. 4: 231-232. PMID 11231189 DOI: 10.1016/S1201-9712(00)90116-4  0.348
2000 Madhi SA, Petersen K, Madhi A, Wasas A, Klugman KP. Impact of human immunodeficiency virus type 1 on the disease spectrum of Streptococcus pneumoniae in South African children Pediatric Infectious Disease Journal. 19: 1141-1147. PMID 11144373 DOI: 10.1097/00006454-200012000-00004  0.359
2000 Adrian PV, Mendrick C, Loebenberg D, McNicholas P, Shaw KJ, Klugman KP, Hare RS, Black TA. Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants. Antimicrobial Agents and Chemotherapy. 44: 3101-6. PMID 11036030 DOI: 10.1128/Aac.44.11.3101-3106.2000  0.38
2000 Du Plessis M, Smith AM, Klugman KP. Analysis of penicillin-binding protein 1b and 2a genes from Streptococcus pneumoniae Microbial Drug Resistance. 6: 127-131. PMID 10990267 DOI: 10.1089/107662900419438  0.341
2000 Smith AM, Klugman KP. Non-penicillin-binding protein mediated high-level penicillin and cephalosporin resistance in a Hungarian clone of Streptococcus pneumoniae Microbial Drug Resistance. 6: 105-110. PMID 10990264 DOI: 10.1089/107662900419401  0.349
2000 Klugman KP, Wortmann G. Levofloxacin-resistant pneumococcus [6] (multiple letters) Clinical Infectious Diseases. 31: 626-627. PMID 10987743 DOI: 10.1086/313958  0.331
2000 Heffelfinger JD, Dowell SF, Jorgensen JH, Klugman KP, Mabry LR, Musher DM, Plouffe JF, Rakowsky A, Schuchat A, Whitney CG. Management of community-acquired pneumonia in the era of pneumococcal resistance: a report from the Drug-Resistant Streptococcus pneumoniae Therapeutic Working Group. Archives of Internal Medicine. 160: 1399-408. PMID 10826451 DOI: 10.1001/Archinte.160.10.1399  0.349
2000 Rowe AK, Deming MS, Schwartz B, Wasas A, Rolka D, Rolka H, Ndoyo J, Klugman KP. Antimicrobial resistance of nasopharyngeal isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in the Central African Republic. The Pediatric Infectious Disease Journal. 19: 438-44. PMID 10819340 DOI: 10.1097/00006454-200005000-00009  0.436
2000 Adrian PV, Zhao W, Black TA, Shaw KJ, Hare RS, Klugman KP. Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action. Antimicrobial Agents and Chemotherapy. 44: 732-8. PMID 10681347 DOI: 10.1128/Aac.44.3.732-738.2000  0.326
2000 Adrian PV, Thomson CJ, Klugman KP, Amyes SG. New gene cassettes for trimethoprim resistance, dfr13, and Streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron. Antimicrobial Agents and Chemotherapy. 44: 355-61. PMID 10639362 DOI: 10.1128/Aac.44.2.355-361.2000  0.337
2000 Rowe AK, Schwartz B, Wasas A, Klugman KP. Evaluation of the Etest as a means of determining the antibiotic susceptibilities of isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in the Central African Republic [3] Journal of Antimicrobial Chemotherapy. 45: 132-134. PMID 10629028 DOI: 10.1093/Jac/45.1.132  0.431
1999 Madhi SA, Klugman KP. Pneumococcal conjugate vaccine - Prospects for intervention in children Seminars in Respiratory Infections. 14: 285-294. PMID 10501316  0.386
1999 Mbelle N, Huebner RE, Wasas AD, Kimura A, Chang I, Klugman KP. Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine. The Journal of Infectious Diseases. 180: 1171-6. PMID 10479145 DOI: 10.1086/315009  0.424
1999 Padayachee T, Klugman KP. Novel expansions of the gene encoding dihydropteroate synthase in trimethoprim-sulfamethoxazole-resistant Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 43: 2225-2230. PMID 10471569 DOI: 10.1128/Aac.43.9.2225  0.363
1999 Klugman KP, Madhi SA. Emergence of drug resistance: Impact on Bacterial meningitis Infectious Disease Clinics of North America. 13: 637-646. PMID 10470559 DOI: 10.1016/S0891-5520(05)70098-2  0.403
1999 Muhe L, Klugman KP. Pneumococcal and Haemophilus influenzae meningitis in a children's hospital in Ethiopia: Serotypes and susceptibility patterns Tropical Medicine and International Health. 4: 421-427. PMID 10444317 DOI: 10.1046/j.1365-3156.1999.00417.x  0.361
1999 Klugman KP, Feldman C. Penicillin- and cephalosporin-resistant Streptococcus pneumoniae Drugs. 58: 1-4. PMID 10439925 DOI: 10.2165/00003495-199958010-00001  0.388
1999 Wasas AD, Huebner RE, Klugman KP. Use of Dorset egg medium for maintenance and transport of Neisseria meningitidis and Haemophilus influenzae type B Journal of Clinical Microbiology. 37: 2045-2046. PMID 10325376 DOI: 10.1128/Jcm.37.6.2045-2046.1999  0.324
1999 Klugman KP, Capper T, Widdowson CA, Koornhof HJ, Moser W. Increased activity of 16-membered lactone ring macrolides against erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae: characterization of South African isolates. The Journal of Antimicrobial Chemotherapy. 42: 729-34. PMID 10052895 DOI: 10.1093/Jac/42.6.729  0.398
1999 Keddy KH, Klugman KP, Hansford CF, Blondeau C, Bouveret Le Cam NN. Persistence of antibodies to the Salmonella typhi Vi capsular polysaccharide vaccine in South African school children ten years after immunization Vaccine. 17: 110-113. PMID 9987143 DOI: 10.1016/S0264-410X(98)00160-1  0.375
1999 Du Plessis M, Smith AM, Klugman KP. Application of pbp1A PCR in identification of penicillin-resistant Streptococcus pneumoniae Journal of Clinical Microbiology. 37: 628-632. PMID 9986824 DOI: 10.1128/Jcm.37.3.628-632.1999  0.354
1999 Jones N, Huebner R, Khoosal M, Crewe-Brown H, Klugman K. The impact of HIV on Streptococcus pneumoniae bacteraemia in a South African population. Aids (London, England). 12: 2177-84. PMID 9833859 DOI: 10.1097/00002030-199816000-00013  0.368
1999 Huebner RE, Wasas A, Mushi A, Mazhani L, Klugman K. Nasopharyngeal carriage and antimicrobial resistance in isolates of Streptococcus pneumoniae and Haemophilus influenzae type b in children under 5 years of age in Botswana. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 3: 18-25. PMID 9831671 DOI: 10.1016/S1201-9712(98)90090-X  0.423
1999 Kanra G, Erdem G, Ceyhan M, Klugman KP, Vasas A. Serotypes and antibacterial susceptibility of pneumococci isolated from children with infections in Ankara in relation to proposed pneumococcal vaccine coverage. Acta Paediatrica Japonica : Overseas Edition. 40: 437-40. PMID 9821702 DOI: 10.1111/j.1442-200X.1998.tb01964.x  0.357
1998 Keddy KH, Klugman KP, Robbins JB. Efficacy of Vi polysaccharide vaccine against strains of Salmonella typhi: Reply Vaccine. 16: 871-872. PMID 9682329 DOI: 10.1016/S0264-410X(98)80024-8  0.382
1998 Yagupsky P, Porat N, Fraser D, Prajgrod F, Merires M, McGee L, Klugman KP, Dagan R. Acquisition, carriage, and transmission of pneumococci with decreased antibiotic susceptibility in young children attending a day care facility in southern Israel. The Journal of Infectious Diseases. 177: 1003-12. PMID 9534975 DOI: 10.1086/515239  0.407
1998 Du Plessis M, Smith AM, Klugman KP. Rapid detection of penicillin-resistant Streptococcus pneumoniae in cerebrospinal fluid by a seminested-PCR strategy Journal of Clinical Microbiology. 36: 453-457. PMID 9466757 DOI: 10.1128/Jcm.36.2.453-457.1998  0.383
1998 Crewe-Brown HH, Karstaedt AS, Saunders GL, Khoosal M, Jones N, Wasas A, Klugman KP. Streptococcus pneumoniae blood culture isolates from patients with and without human immunodeficiency virus infection: alterations in penicillin susceptibilities and in serogroups or serotypes. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 25: 1165-72. PMID 9402377 DOI: 10.1086/516104  0.397
1998 Klugman KP, Keddy K, Cam NBL, Hansford F. Long term serological response to Vi vaccine and protective immunity Medical Journal of Indonesia. 7: 88-88. DOI: 10.13181/Mji.V7Isupp1.1045  0.321
1998 Wang H, Huebner R, Chen M, Klugman K. Antibiotic Susceptibility Patterns ofStreptococcus pneumoniae in China and Comparison of MICs by Agar Dilution and E-Test Methods Antimicrobial Agents and Chemotherapy. 42: 2633-2636. DOI: 10.1128/Aac.42.10.2633  0.402
1997 Klugman KP, Capper T. Concentration-dependent killing of antibiotic-resistant pneumococci by the methoxyquinolone moxifloxacin Journal of Antimicrobial Chemotherapy. 40: 797-802. PMID 9462430 DOI: 10.1093/Jac/40.6.797  0.35
1997 Smith AM, Klugman KP. Three predominant clones identified within penicillin-resistant South African isolates of Streptococcus pneumoniae Microbial Drug Resistance. 3: 385-389. PMID 9442492 DOI: 10.1089/Mdr.1997.3.385  0.412
1997 Adrian PV, Klugman KP. Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 41: 2406-2413. PMID 9371341 DOI: 10.1128/Aac.41.11.2406  0.385
1997 Friedland IR, Klugman KP. Cerebrospinal fluid bactericidal activity against cephalosporin- resistant Streptococcus pneumoniae in children with meningitis treated with high-dosage cefotaxime Antimicrobial Agents and Chemotherapy. 41: 1888-1891. PMID 9303379 DOI: 10.1128/Aac.41.9.1888  0.349
1997 McGee L, Klugman KP, Friedland D, Lee HJ. Spread of the Spanish multi-resistant serotype 23F clone of Streptococcus pneumoniae to Seoul, Korea Microbial Drug Resistance. 3: 253-257. PMID 9270994 DOI: 10.1089/Mdr.1997.3.253  0.319
1997 Klugman KP, Gootz TD. In-vitro and in-vivo activity of trovafloxacin against Streptococcus pneumoniae Journal of Antimicrobial Chemotherapy. 39: 51-55. PMID 9222070 DOI: 10.1093/Jac/39.Suppl_2.51  0.348
1997 Klugman K, Goldstein F, Kohno S, Baquero F. The role of fourth-generation cephalosporins in the treatment of infections caused by penicillin-resistant streptococci Clinical Microbiology and Infection. 3. DOI: 10.1111/J.1469-0691.1997.Tb00646.X  0.423
1997 Klugman KP, Feldman C. The clinical relevance of antibiotic resistance in the management of pneumococcal pneumonia Clinical Pulmonary Medicine. 4: 190-193. DOI: 10.1097/00019048-199805000-00006  0.408
1997 Klugman KP. Pneumococcal resistance - The challenge of childhood infection Research and Clinical Forums. 19.  0.311
1996 Widdowson CA, Klugman KP, Hanslo D. Identification of the tetracycline resistance gene, tet(O), in Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 40: 2891-2893. PMID 9124862 DOI: 10.1128/Aac.40.12.2891  0.327
1996 Klugman KP, Capper T, Bryskier A. In vitro susceptibility of penicillin-resistant Streptococcus pneumoniae to levofloxacin, selection of resistant mutants, and time-kill synergy studies of levofloxacin combined with vancomycin, teicoplanin, fusidic acid, and rifampin Antimicrobial Agents and Chemotherapy. 40: 2802-2804. PMID 9124844 DOI: 10.1128/Aac.40.12.2802  0.375
1996 Klugman KP. The clinical relevance of in-vitro resistance to penicillin, ampicillin, amoxycillin and alternative agents, for the treatment of community-acquired pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzas and Moraxella catarrhalis Journal of Antimicrobial Chemotherapy. 38: 133-140. PMID 8858479 DOI: 10.1093/Jac/38.Suppl_A.133  0.395
1996 Klugman KP, Koornhof HJ, Robbins JB, Le Cam NN. Immunogenicity, efficacy and serological correlate of protection of Salmonella typhi Vi capsular polysaccharide vaccine three years after immunization Vaccine. 14: 435-438. PMID 8735556 DOI: 10.1016/0264-410X(95)00186-5  0.364
1996 Klugman K, Wasas A. In-vitro activity of the fluoroquinolone trovafloxacin against penicillin-susceptible and -resistant Streptococcus pneumoniae. The Journal of Antimicrobial Chemotherapy. 36: 873-4. PMID 8626270 DOI: 10.1093/Jac/36.5.873  0.38
1995 Klugman KP, Friedland IR. Antibiotic-resistant pneumococci in pediatric disease Microbial Drug Resistance (Larchmont, N.Y.). 1: 5-8. PMID 9156379 DOI: 10.1089/Mdr.1995.1.5  0.464
1995 Klugman KP, Friedland IR, Bradley JS. Bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in cerebrospinal fluid of children with acute bacterial meningitis Antimicrobial Agents and Chemotherapy. 39: 1988-1992. PMID 8540704 DOI: 10.1128/Aac.39.9.1988  0.398
1995 Smith AM, Klugman KP. Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. 39: 859-867. PMID 7785985 DOI: 10.1128/Aac.39.4.859  0.354
1995 Adrian PV, Klugman KP, Amyes SGB. Prevalence of trimethoprim resistant dihydrofolate reductase genes identified with oligonucleotide probes in plasmids from isolates of commensal faecal flora Journal of Antimicrobial Chemotherapy. 35: 497-508. PMID 7628984 DOI: 10.1093/Jac/35.4.497  0.343
1995 Adrian PV, Thomson CJ, Klugman KP, Amyes SG. Prevalence and genetic location of non-transferable trimethoprim resistant dihydrofolate reductase genes in South African commensal faecal isolates. Epidemiology and Infection. 115: 255-67. PMID 7589265 DOI: 10.1017/S0950268800058386  0.323
1995 Sniadack DH, Schwartz B, Lipman H, Bogaerts J, Butler JC, Dagan R, Echaniz-Aviles G, Lloyd-Evans N, Fenoll A, Girgis NI, Henrichsen J, Klugman K, Lehmann D, Takala AK, Vandepitte J, et al. Potential interventions for the prevention of childhood pneumonia: geographic and temporal differences in serotype and serogroup distribution of sterile site pneumococcal isolates from children--implications for vaccine strategies. Pediatric Infectious Disease Journal. 14: 503-509. DOI: 10.1097/00006454-199506000-00007  0.422
1994 Blumberg LH, Klugman KP. Control of methicillin-resistant Staphylococcus aureus bacteraemia in high-risk areas European Journal of Clinical Microbiology &Amp; Infectious Diseases. 13: 82-85. PMID 8168568 DOI: 10.1007/Bf02026131  0.319
1994 Klugman KP. Activity of teicoplanin and vancomycin against penicillin-resistant pneumococci European Journal of Clinical Microbiology &Amp; Infectious Diseases. 13: 1-2. PMID 8168552 DOI: 10.1007/Bf02026115  0.395
1994 Klugman KP, Coffey TJ, Smith A, Wasas A, Meyers M, Spratt BG. Cluster of an erythromycin-resistant variant of the Spanish multiply resistant 23F clone of Streptococcus pneumoniae in South Africa. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 13: 171-4. PMID 8013492 DOI: 10.1007/Bf01982193  0.377
1994 Dagan R, Yagupsky P, Goldbart A, Wasas A, Klugman K. Increasing Prevalence Of Penicillin-Resistant Pneumococcal Infections In Children In Southern Israel: Implications For Future Immunization Policies Pediatric Infectious Disease Journal. 13: 782-786. PMID 7808846 DOI: 10.1097/00006454-199409000-00006  0.489
1994 Reed RP, Klugman KP. Neonatal typhoid fever Pediatric Infectious Disease Journal. 13: 774-777. PMID 7808844 DOI: 10.1097/00006454-199409000-00004  0.352
1994 Klugman KP. Pneumococcal resistance to the third-generation cephalosporins: clinical, laboratory and molecular aspects International Journal of Antimicrobial Agents. 4: 63-67. DOI: 10.1016/0924-8579(94)90063-9  0.363
1993 Walkden D, Klugman KP, Vally S, Naidoo P. Urinary tract infection with Corynebacterium urealyticum in South Africa European Journal of Clinical Microbiology &Amp; Infectious Diseases. 12: 18-24. PMID 8462556 DOI: 10.1007/Bf01997051  0.358
1993 Smith AM, Klugman KP, Coffey TJ, Spratt BG. Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa. Antimicrobial Agents and Chemotherapy. 37: 1938-44. PMID 8239609 DOI: 10.1128/Aac.37.9.1938  0.317
1992 Friedland IR, Klugman KP. Antibiotic-Resistant Pneumococcal Disease in South African Children American Journal of Diseases of Children. 146: 920-923. PMID 1636657 DOI: 10.1001/Archpedi.1992.02160200042023  0.442
1992 Koornhof HJ, Wasas A, Klugman K. Antimicrobial resistance in Streptococcus pneumoniae: a South African perspective. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 15: 84-94. PMID 1617077 DOI: 10.1093/Clinids/15.1.84  0.405
1992 Friedland IR, Funk E, Khoosal M, Klugman KP. Increased resistance to amikacin in a neonatal unit following intensive amikacin usage Antimicrobial Agents and Chemotherapy. 36: 1596-1600. PMID 1416839 DOI: 10.1128/Aac.36.8.1596  0.395
1992 Friedland IR, Klugman KP. Failure of chloramphenicol therapy in penicillin-resistant pneumococcal meningitis The Lancet. 339: 405-408. PMID 1346668 DOI: 10.1016/0140-6736(92)90087-J  0.303
1990 Klugman KP. Pneumococcal resistance to antibiotics Clinical Microbiology Reviews. 3: 171-196. PMID 2187594 DOI: 10.1128/Cmr.3.2.171  0.409
1988 Klugman KP, Koornhof HJ. Drug resistance patterns and serogroups or serotypes of pneumococcal isolates from cerebrospinal fluid or blood, 1979-1986 Journal of Infectious Diseases. 158: 956-964. PMID 3183429 DOI: 10.1093/Infdis/158.5.956  0.438
1988 Klugman KP, Koornhof HJ, Kuhnle V. In Reply American Journal of Diseases of Children. 142: 254. DOI: 10.1001/Archpedi.1988.02150030019009  0.365
1987 Sacho H, Klugman KP, Koornhof HJ, Ruff P. Community-acquired pneumonia in an adult due to a multiply-resistant pneumococcus Journal of Infection. 14: 188-189. PMID 3572020 DOI: 10.1016/S0163-4453(87)92127-X  0.328
1986 Klugman KP, Koornhof HJ, Kuhnle V. Clinical and Nasopharyngeal Isolates of Unusual Multiply Resistant Pneumococci American Journal of Diseases of Children. 140: 1186-1190. PMID 3766492 DOI: 10.1001/Archpedi.1986.02140250112045  0.426
1986 Klugman KP, Koornhof HJ, Wasas A, Storey K, Gilbertson I. Carriage of penicillin resistant pneumococci Archives of Disease in Childhood. 61: 377-381. PMID 3707189 DOI: 10.1136/Adc.61.4.377  0.415
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