Robert Farese - Publications

Affiliations: 
Cell Biology University of California, San Francisco, San Francisco, CA 
Area:
Cell Biology

393 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kumar S, Chitraju C, Farese R, Walther T, Burd CG. Conditional targeting of phosphatidylserine decarboxylase to lipid droplets. Biology Open. PMID 33593792 DOI: 10.1242/bio.058516  1
2021 Farese RV, Walther TC. The power of two: lessons from a scientific partnership. The Journal of Clinical Investigation. 131. PMID 33463550 DOI: 10.1172/JCI145966  1
2021 Sajan MP, Hansen BC, Acevedo‐Duncan M, Kindy MS, Cooper DR, Farese RV. Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin‐resistant forms of obesity and type 2 diabetes mellitus Medcomm. 2: 3-16. DOI: 10.1002/MCO2.54  0.01
2020 Christiano R, Arlt H, Kabatnik S, Mejhert N, Lai ZW, Farese RV, Walther TC. A Systematic Protein Turnover Map for Decoding Protein Degradation. Cell Reports. 33: 108378. PMID 33176155 DOI: 10.1016/j.celrep.2020.108378  1
2020 Chitraju C, Fischer AW, Farese RV, Walther TC. Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis. Cell Reports. 33: 108348. PMID 33147469 DOI: 10.1016/j.celrep.2020.108348  1
2020 Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV. FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. The Journal of Cell Biology. 219. PMID 32915949 DOI: 10.1083/Jcb.202006111  1
2020 Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, ... Farese RV, et al. Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature. PMID 32866962 DOI: 10.1038/S41586-020-2709-7  1
2020 Olarte MJ, Kim S, Sharp ME, Swanson JMJ, Farese RV, Walther TC. Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting. Developmental Cell. PMID 32730754 DOI: 10.1016/J.Devcel.2020.07.001  1
2020 Sui X, Wang K, Gluchowski NL, Elliott SD, Liao M, Walther TC, Farese RV. Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature. 581: 323-328. PMID 32433611 DOI: 10.1038/S41586-020-2289-6  1
2020 Petit CS, Lee JJ, Boland S, Swarup S, Christiano R, Lai ZW, Mejhert N, Elliott SD, McFall D, Haque S, Huang EJ, Bronson RT, Harper JW, Farese RV, Walther TC. Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant mice, a model of motor neuron degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 32345721 DOI: 10.1073/Pnas.1913956117  1
2020 Mejhert N, Kuruvilla L, Gabriel KR, Elliott SD, Guie MA, Wang H, Lai ZW, Lane EA, Christiano R, Danial NN, Farese RV, Walther TC. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Molecular Cell. PMID 32023484 DOI: 10.1016/J.Molcel.2020.01.014  1
2019 Chung J, Wu X, Lambert TJ, Lai ZW, Walther TC, Farese RV. LDAF1 and Seipin Form a Lipid Droplet Assembly Complex. Developmental Cell. PMID 31708432 DOI: 10.1016/J.Devcel.2019.10.006  1
2019 Walther TC, Farese RV. Un-phased: Lipid Droplets Modulate the Bioavailability of Antibiotics. Developmental Cell. 50: 530-532. PMID 31505174 DOI: 10.1016/J.Devcel.2019.08.009  1
2019 Gluchowski NL, Gabriel KR, Chitraju C, Bronson RT, Mejhert N, Boland S, Wang K, Lai ZW, Farese RV, Walther TC. Hepatocyte Deletion of Triglyceride-Synthesis Enzyme DGAT2 Reduces Steatosis without Increasing Inflammation or Fibrosis. Hepatology (Baltimore, Md.). PMID 31081165 DOI: 10.1002/Hep.30765  1
2019 Chitraju C, Walther TC, Farese RV. The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes. Journal of Lipid Research. 60: 1112-1120. PMID 30936184 DOI: 10.1194/Jlr.M093112  1
2019 Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, ... Farese RV, et al. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Molecular Cell. PMID 30846318 DOI: 10.1016/J.Molcel.2019.01.036  1
2018 Farese RV, Sajan MP. Atypical PKC: therapeutic target for Alzheimer's? Aging. 11: 13-14. PMID 30573704 DOI: 10.18632/aging.101730  1
2018 Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, ... ... Farese RV, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Molecular Cell. PMID 30527540 DOI: 10.1016/J.Molcel.2018.11.028  1
2018 Sui X, Arlt H, Brock KP, Lai ZW, DiMaio F, Marks DS, Liao M, Farese RV, Walther TC. Cryo-electron microscopy structure of the lipid droplet-formation protein seipin. The Journal of Cell Biology. PMID 30327422 DOI: 10.1083/Jcb.201809067  1
2018 Nguyen AD, Nguyen TA, Singh RK, Eberlé D, Zhang J, Abate JP, Robles A, Koliwad S, Huang EJ, Maxfield FR, Walther TC, Farese RV. Progranulin in the hematopoietic compartment protects mice from atherosclerosis. Atherosclerosis. 277: 145-154. PMID 30212683 DOI: 10.1016/J.Atherosclerosis.2018.08.042  1
2018 Jayson CBK, Arlt H, Fischer AW, Lai ZW, Farese RV, Walther TC. Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells. Molecular Biology of the Cell. mbcE18050282. PMID 29949452 DOI: 10.1091/Mbc.E18-05-0282  1
2018 Nguyen AD, Nguyen TA, Zhang J, Devireddy S, Zhou P, Karydas AM, Xu X, Miller BL, Rigo F, Ferguson SM, Huang EJ, Walther TC, Farese RV. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. PMID 29511098 DOI: 10.1073/Pnas.1722344115  1
2018 Li Z, Lai ZW, Christiano R, Gazos-Lopes F, Walther TC, Farese RV. Global Analyses of Selective Insulin Resistance in Hepatocytes due to Palmitate Lipotoxicity. Molecular & Cellular Proteomics : McP. PMID 29414761 DOI: 10.1074/Mcp.Ra117.000560  1
2018 Prévost C, Sharp ME, Kory N, Lin Q, Voth GA, Farese RV, Walther TC. Mechanism and Determinants of Amphipathic Helix-Containing Protein Targeting to Lipid Droplets. Developmental Cell. 44: 73-86.e4. PMID 29316443 DOI: 10.1016/J.Devcel.2017.12.011  1
2017 Inloes JM, Kiosses WB, Wang H, Walther TC, Farese RV, Cravatt BF. Functional Contribution of the Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2 to the Formation and Content of Lipid Droplets. Biochemistry. PMID 29278326 DOI: 10.1021/Acs.Biochem.7B01028  1
2017 Sajan MP, Lee MC, Foufelle F, Sajan J, Cleland C, Farese RV. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance. Cellular Signalling. PMID 29269047 DOI: 10.1016/j.cellsig.2017.12.005  1
2017 Sha SJ, Miller ZA, Min SW, Zhou Y, Brown J, Mitic LL, Karydas A, Koestler M, Tsai R, Corbetta-Rastelli C, Lin S, Hare E, Fields S, Fleischmann KE, Powers R, ... ... Farese RV, et al. An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations. Alzheimer's & Dementia (New York, N. Y.). 3: 507-512. PMID 29124108 DOI: 10.1016/J.Trci.2017.08.002  1
2017 Sajan MP, Hansen BC, Higgs MG, Kahn CR, Braun U, Leitges M, Park CR, Diamond DM, Farese RV. Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease. Neurobiology of Aging. PMID 29032894 DOI: 10.1016/J.Neurobiolaging.2017.09.001  1
2017 Walther TC, Chung J, Farese RV. Lipid Droplet Biogenesis. Annual Review of Cell and Developmental Biology. PMID 28793795 DOI: 10.1146/Annurev-Cellbio-100616-060608  1
2017 Chitraju C, Mejhert N, Haas JT, Diaz-Ramirez LG, Grueter CA, Imbriglio JE, Pinto S, Koliwad SK, Walther TC, Farese RV. Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis. Cell Metabolism. 26: 407-418.e3. PMID 28768178 DOI: 10.1016/J.Cmet.2017.07.012  1
2017 Krabbe G, Minami SS, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC, Sayed F, Merlini M, Ward ME, Perry DC, Lee SE, ... ... Farese RV, et al. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28438992 DOI: 10.1073/Pnas.1700477114  1
2017 Gluchowski NL, Becuwe M, Walther TC, Farese RV. Lipid droplets and liver disease: from basic biology to clinical implications. Nature Reviews. Gastroenterology & Hepatology. 14: 343-355. PMID 28428634 DOI: 10.1038/Nrgastro.2017.32  1
2017 Gluchowski NL, Chitraju C, Picoraro JA, Mejhert N, Pinto S, Xin W, Kamin DS, Winter HS, Chung WK, Walther TC, Farese RV. Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea. Journal of Lipid Research. PMID 28373485 DOI: 10.1194/Jlr.P075119  1
2017 Dorfman MD, Krull JE, Scarlett JM, Guyenet SJ, Sajan MP, Damian V, Nguyen HT, Leitges M, Morton GJ, Farese RV, Schwartz MW, Thaler JP. Deletion of Protein Kinase C Lambda in POMC Neurons Predisposes to Diet-Induced Obesity. Diabetes. PMID 28073831 DOI: 10.2337/Db16-0482  1
2016 Kory N, Grond S, Kamat SS, Li Z, Krahmer N, Chitraju C, Zhou P, Fröhlich F, Semova I, Ejsing C, Zechner R, Cravatt BF, Farese RV, Walther TC. Mice Lacking Lipid Droplet-Associated Hydrolase, a Gene Linked to Human Prostate Cancer, Have Normal Cholesterol Ester Metabolism. Journal of Lipid Research. PMID 27836991 DOI: 10.1194/Jlr.M072538  1
2016 Fröhlich F, Olson DK, Christiano R, Farese RV, Walther TC. Proteomic and phosphoproteomic analyses of yeast reveal the global cellular response to sphingolipid depletion. Proteomics. 16: 2759-2763. PMID 27717283 DOI: 10.1002/Pmic.201600269  1
2016 Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte MJ, Lin Q, Fröhlich F, Hannibal-Bach HK, ... ... Farese RV, et al. Seipin is required for converting nascent to mature lipid droplets. Elife. 5. PMID 27564575 DOI: 10.7554/Elife.16582  1
2016 Tsokas P, Hsieh C, Yao Y, Lesburguères E, Wallace EJ, Tcherepanov A, Jothianandan D, Hartley BR, Pan L, Rivard B, Farese RV, Sajan MP, Bergold PJ, Hernández AI, Cottrell JE, et al. Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice. Elife. 5. PMID 27187150 DOI: 10.7554/Elife.14846  1
2016 Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, ... ... Farese RV, et al. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell. PMID 27114033 DOI: 10.1016/J.Cell.2016.04.001  1
2016 Kory N, Farese RV, Walther TC. Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets. Trends in Cell Biology. 26: 535-546. PMID 26995697 DOI: 10.1016/J.Tcb.2016.02.007  1
2016 Mp S, Bc H, Ra I, Jp S, C A, S S, U B, M L, Mg FH, Rv F. Brain Insulin Signaling is Increased in Insulin-Resistant States and Decreases in FoxOs and PGC-1α and Increases in Aβ1-40.42 and Phospho-Tau May Abet Alzheimer Development. Diabetes. PMID 26895791 DOI: 10.2337/db15-1428  0.01
2016 Agarwal AK, Tunison K, Dalal JS, Yen CE, Farese RV, Horton JD, Garg A. Mogat1 deletion does not ameliorate hepatic steatosis in lipodystrophic (Agpat2-/-) or obese (ob/ob) mice. Journal of Lipid Research. PMID 26880786 DOI: 10.1194/jlr.M065896  1
2016 Farese RV, Walther TC. Lipid droplets go nuclear. The Journal of Cell Biology. 212: 7-8. PMID 26728852 DOI: 10.1083/Jcb.201512056  1
2016 Kory N, Farese RV, Walther TC. Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets Trends in Cell Biology. 26: 535-546. DOI: 10.1016/j.tcb.2016.02.007  1
2016 Taniguchi C, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley L, Kahn C. Divergent Regulation of Hepatic Glucose and Lipid Metabolism by Phosphoinositide 3-Kinase via Akt and PKCλ/ζ Cell Metabolism. 23: 386. DOI: 10.1016/J.Cmet.2016.01.016  0.01
2015 Yu H, Fujii NL, Toyoda T, An D, Farese RV, Leitges M, Hirshman MF, Mul JD, Goodyear LJ. Contraction stimulates muscle glucose uptake independent of atypical PKC. Physiological Reports. 3. PMID 26564060 DOI: 10.14814/phy2.12565  1
2015 Sajan MP, Ivey RA, Farese RV. BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans. Metabolism: Clinical and Experimental. 64: 1454-65. PMID 26386696 DOI: 10.1016/j.metabol.2015.08.011  1
2015 Fröhlich F, Petit C, Kory N, Christiano R, Hannibal-Bach HK, Graham M, Liu X, Ejsing CS, Farese RV, Walther TC. The GARP complex is required for cellular sphingolipid homeostasis. Elife. 4. PMID 26357016 DOI: 10.7554/Elife.08712  1
2015 Kory N, Thiam AR, Farese RV, Walther TC. Protein Crowding Is a Determinant of Lipid Droplet Protein Composition. Developmental Cell. 34: 351-63. PMID 26212136 DOI: 10.1016/J.Devcel.2015.06.007  1
2015 Zhang N, Liang H, Farese RV, Li J, Musi N, Hussey SE. Pharmacological TLR4 Inhibition Protects against Acute and Chronic Fat-Induced Insulin Resistance in Rats. Plos One. 10: e0132575. PMID 26196892 DOI: 10.1371/Journal.Pone.0132575  0.01
2015 Sajan MP, Ivey RA, Lee MC, Farese RV. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation. Journal of Lipid Research. 56: 70-80. PMID 25395359 DOI: 10.1194/jlr.M052977  1
2015 Sajan MP, Ivey RA, Farese RV. BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans Metabolism: Clinical and Experimental. 64: 1454-1465. DOI: 10.1016/j.metabol.2015.08.011  1
2015 Olson DK, Fröhlich F, Farese RV, Walther TC. Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. DOI: 10.1016/j.bbalip.2015.12.021  1
2014 Farese RV, Lee MC, Sajan MP. Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes Mellitus. Journal of Clinical Medicine. 3: 724-40. PMID 26237474 DOI: 10.3390/jcm3030724  1
2014 Camus G, Schweiger M, Herker E, Harris C, Kondratowicz AS, Tsou CL, Farese RV, Herath K, Previs SF, Roddy TP, Pinto S, Zechner R, Ott M. The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets. The Journal of Biological Chemistry. 289: 35770-80. PMID 25381252 DOI: 10.1074/Jbc.M114.587816  0.01
2014 Mul JD, Begg DP, Haller AM, Pressler JW, Sorrell J, Woods SC, Farese RV, Seeley RJ, Sandoval DA. MGAT2 deficiency and vertical sleeve gastrectomy have independent metabolic effects in the mouse. American Journal of Physiology. Endocrinology and Metabolism. 307: E1065-72. PMID 25315695 DOI: 10.1152/Ajpendo.00376.2014  1
2014 Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV, Gan L. Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models. Nature Medicine. 20: 1157-64. PMID 25261995 DOI: 10.1038/nm.3672  1
2014 Farese RV, Lee MC, Sajan MP. Atypical PKC: a target for treating insulin-resistant disorders of obesity, the metabolic syndrome and type 2 diabetes mellitus. Expert Opinion On Therapeutic Targets. 18: 1163-75. PMID 25213731 DOI: 10.1517/14728222.2014.944897  1
2014 Liu L, Trent CM, Fang X, Son NH, Jiang H, Blaner WS, Hu Y, Yin YX, Farese RV, Homma S, Turnbull AV, Eriksson JW, Hu SL, Ginsberg HN, Huang LS, et al. Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure. The Journal of Biological Chemistry. 289: 29881-91. PMID 25157099 DOI: 10.1074/jbc.M114.601864  1
2014 Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, ... ... Farese RV, et al. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. The Journal of Experimental Medicine. 211: 1937-45. PMID 25155018 DOI: 10.1084/Jem.20140214  1
2014 Ivey RA, Sajan MP, Farese RV. Requirements for pseudosubstrate arginine residues during autoinhibition and phosphatidylinositol 3,4,5-(POâ‚„)₃-dependent activation of atypical PKC. The Journal of Biological Chemistry. 289: 25021-30. PMID 25035426 DOI: 10.1074/jbc.M114.565671  1
2014 Sajan MP, Ivey RA, Lee M, Mastorides S, Jurczak MJ, Samuels VT, Shulman GI, Braun U, Leitges M, Farese RV. PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes. Molecular Endocrinology (Baltimore, Md.). 28: 1097-107. PMID 24877563 DOI: 10.1210/Me.2014-1025  1
2014 Fu D, Yu Y, Folick A, Currie E, Farese RV, Tsai TH, Xie XS, Wang MC. In vivo metabolic fingerprinting of neutral lipids with hyperspectral stimulated Raman scattering microscopy. Journal of the American Chemical Society. 136: 8820-8. PMID 24869754 DOI: 10.1021/Ja504199S  1
2014 Currie E, Guo X, Christiano R, Chitraju C, Kory N, Harrison K, Haas J, Walther TC, Farese RV. High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation. Journal of Lipid Research. 55: 1465-1477. PMID 24868093 DOI: 10.1194/Jlr.M050229  1
2014 Wilfling F, Haas JT, Walther TC, Farese RV. Lipid droplet biogenesis. Current Opinion in Cell Biology. 29: 39-45. PMID 24736091 DOI: 10.1016/J.Ceb.2014.03.008  1
2014 Sajan MP, Acevedo-Duncan ME, Standaert ML, Ivey RA, Lee M, Farese RV. Akt-dependent phosphorylation of hepatic FoxO1 is compartmentalized on a WD40/ProF scaffold and is selectively inhibited by aPKC in early phases of diet-induced obesity. Diabetes. 63: 2690-701. PMID 24705403 DOI: 10.2337/db13-1863  1
2014 Sajan MP, Jurzak MJ, Samuels VT, Shulman GI, Braun U, Leitges M, Farese RV. Impairment of insulin-stimulated glucose transport and ERK activation by adipocyte-specific knockout of PKC-λ produces a phenotype characterized by diminished adiposity and enhanced insulin suppression of hepatic gluconeogenesis. Adipocyte. 3: 19-29. PMID 24575365 DOI: 10.4161/adip.26305  1
2014 Wilfling F, Thiam AR, Olarte MJ, Wang J, Beck R, Gould TJ, Allgeyer ES, Pincet F, Bewersdorf J, Farese RV, Walther TC. Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting. Elife. 3: e01607. PMID 24497546 DOI: 10.7554/Elife.01607  1
2013 Thiam AR, Farese RV, Walther TC. The biophysics and cell biology of lipid droplets. Nature Reviews. Molecular Cell Biology. 14: 775-86. PMID 24220094 DOI: 10.1038/Nrm3699  1
2013 Zhang Z, Almeida S, Lu Y, Nishimura AL, Peng L, Sun D, Wu B, Karydas AM, Tartaglia MC, Fong JC, Miller BL, Farese RV, Moore MJ, Shaw CE, Gao FB. Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations. Plos One. 8: e76055. PMID 24143176 DOI: 10.1371/Journal.Pone.0076055  1
2013 Nguyen AD, Nguyen TA, Martens LH, Mitic LL, Farese RV. Progranulin: at the interface of neurodegenerative and metabolic diseases. Trends in Endocrinology and Metabolism: Tem. 24: 597-606. PMID 24035620 DOI: 10.1016/j.tem.2013.08.003  1
2013 Sajan MP, Ivey RA, Farese RV. Metformin action in human hepatocytes: coactivation of atypical protein kinase C alters 5'-AMP-activated protein kinase effects on lipogenic and gluconeogenic enzyme expression. Diabetologia. 56: 2507-16. PMID 23933835 DOI: 10.1007/s00125-013-3010-1  1
2013 Surma MA, Klose C, Peng D, Shales M, Mrejen C, Stefanko A, Braberg H, Gordon DE, Vorkel D, Ejsing CS, Farese R, Simons K, Krogan NJ, Ernst R. A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Molecular Cell. 51: 519-30. PMID 23891562 DOI: 10.1016/J.Molcel.2013.06.014  1
2013 Currie E, Schulze A, Zechner R, Walther TC, Farese RV. Cellular fatty acid metabolism and cancer. Cell Metabolism. 18: 153-61. PMID 23791484 DOI: 10.1016/J.Cmet.2013.05.017  1
2013 Krahmer N, Farese RV, Walther TC. Balancing the fat: Lipid droplets and human disease Embo Molecular Medicine. 5: 905-915. PMID 23740690 DOI: 10.1002/Emmm.201100671  1
2013 Chen X, Chang J, Deng Q, Xu J, Nguyen TA, Martens LH, Cenik B, Taylor G, Hudson KF, Chung J, Yu K, Yu P, Herz J, Farese RV, Kukar T, et al. Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9202-13. PMID 23699531 DOI: 10.1523/Jneurosci.5336-12.2013  1
2013 Klemm RW, Norton JP, Cole RA, Li CS, Park SH, Crane MM, Li L, Jin D, Boye-Doe A, Liu TY, Shibata Y, Lu H, Rapoport TA, Farese RV, Blackstone C, et al. A conserved role for atlastin GTPases in regulating lipid droplet size. Cell Reports. 3: 1465-75. PMID 23684613 DOI: 10.1016/J.Celrep.2013.04.015  1
2013 Filiano AJ, Martens LH, Young AH, Warmus BA, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang EJ, Gao FB, Farese RV, Roberson ED. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5352-61. PMID 23516300 DOI: 10.1523/Jneurosci.6103-11.2013  1
2013 Camus G, Herker E, Modi AA, Haas JT, Ramage HR, Farese RV, Ott M. Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core. The Journal of Biological Chemistry. 288: 9915-23. PMID 23420847 DOI: 10.1074/Jbc.M112.434910  0.01
2013 Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Fröhlich F, Liu X, Buhman KK, Coleman RA, Bewersdorf J, Farese RV, et al. Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. Developmental Cell. 24: 384-99. PMID 23415954 DOI: 10.1016/J.Devcel.2013.01.013  1
2013 Nguyen AD, Nguyen TA, Cenik B, Yu G, Herz J, Walther TC, Davidson WS, Farese RV. Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). The Journal of Biological Chemistry. 288: 8627-35. PMID 23364791 DOI: 10.1074/Jbc.M112.441949  1
2013 Krahmer N, Hilger M, Kory N, Wilfling F, Stoehr G, Mann M, Farese RV, Walther TC. Protein correlation profiles identify lipid droplet proteins with high confidence. Molecular & Cellular Proteomics : McP. 12: 1115-26. PMID 23319140 DOI: 10.1074/Mcp.M112.020230  1
2013 Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV, de Cabo R, Ulrich S, Akassoglou K, et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (New York, N.Y.). 339: 211-4. PMID 23223453 DOI: 10.1126/Science.1227166  1
2013 Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, ... ... Farese R, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/J.Jalz.2012.03.003  1
2013 Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, ... ... Farese R, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 176-88. PMID 23043900 DOI: 10.1016/J.Jalz.2012.03.002  1
2012 Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV. DGAT1 mutation is linked to a congenital diarrheal disorder. The Journal of Clinical Investigation. 122: 4680-4. PMID 23114594 DOI: 10.1172/Jci64873  1
2012 Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV, Gitler AD. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nature Genetics. 44: 1302-9. PMID 23104007 DOI: 10.1038/Ng.2434  1
2012 Eichmann TO, Kumari M, Haas JT, Farese RV, Zimmermann R, Lass A, Zechner R. Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases. The Journal of Biological Chemistry. 287: 41446-57. PMID 23066022 DOI: 10.1074/jbc.M112.400416  1
2012 Almeida S, Zhang Z, Coppola G, Mao W, Futai K, Karydas A, Geschwind MD, Tartaglia MC, Gao F, Gianni D, Sena-Esteves M, Geschwind DH, Miller BL, Farese RV, Gao FB. Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects. Cell Reports. 2: 789-98. PMID 23063362 DOI: 10.1016/J.Celrep.2012.09.007  1
2012 Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of Clinical Investigation. 122: 3955-9. PMID 23041626 DOI: 10.1172/Jci63113  1
2012 Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV, Mak HY. The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. The Journal of Cell Biology. 198: 895-911. PMID 22927462 DOI: 10.1083/jcb.201201139  1
2012 Haas JT, Miao J, Chanda D, Wang Y, Zhao E, Haas ME, Hirschey M, Vaitheesvaran B, Farese RV, Kurland IJ, Graham M, Crooke R, Foufelle F, Biddinger SB. Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. Cell Metabolism. 15: 873-84. PMID 22682225 DOI: 10.1016/J.Cmet.2012.05.002  1
2012 Farese RV, Zechner R, Newgard CB, Walther TC. The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance Cell Metabolism. 15: 570-573. PMID 22560209 DOI: 10.1016/J.Cmet.2012.03.004  1
2012 Walther TC, Farese RV. Lipid droplets and cellular lipid metabolism Annual Review of Biochemistry. 81: 687-714. PMID 22524315 DOI: 10.1146/Annurev-Biochem-061009-102430  1
2012 Zhang J, Kelley KL, Marshall SM, Davis MA, Wilson MD, Sawyer JK, Farese RV, Brown JM, Rudel LL. Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood. Journal of Lipid Research. 53: 1144-52. PMID 22460046 DOI: 10.1194/Jlr.M024356  1
2012 Farese RV, Sajan MP. Atypical protein kinase C in cardiometabolic abnormalities Current Opinion in Lipidology. 23: 175-181. PMID 22449812 DOI: 10.1097/MOL.0b013e328352c4c7  1
2012 Sajan MP, Farese RV. Insulin signalling in hepatocytes of humans with type 2 diabetes: Excessive production and activity of protein kinase C-ι (PKC-ι) and dependent processes and reversal by PKC-ι inhibitors Diabetologia. 55: 1446-1457. PMID 22349071 DOI: 10.1007/s00125-012-2477-5  1
2012 Streeper RS, Grueter CA, Salomonis N, Cases S, Levin MC, Koliwad SK, Zhou P, Hirschey MD, Verdin E, Farese RV. Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. Aging. 4: 13-27. PMID 22291164  1
2012 Sajan MP, Nimal S, Mastorides S, Acevedo-Duncan M, Kahn CR, Fields AP, Braun U, Leitges M, Farese RV. Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ι. Metabolism: Clinical and Experimental. 61: 459-69. PMID 22225955 DOI: 10.1016/J.Metabol.2011.12.008  1
2012 Tschöp MH, Speakman JR, Arch JR, Auwerx J, Brüning JC, Chan L, Eckel RH, Farese RV, Galgani JE, Hambly C, Herman MA, Horvath TL, Kahn BB, Kozma SC, Maratos-Flier E, et al. A guide to analysis of mouse energy metabolism. Nature Methods. 9: 57-63. PMID 22205519 DOI: 10.1038/Nmeth.1806  1
2012 Filiano A, Martens LH, Young A, Warmus B, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang E, Gao F, Farese R, Roberson E. O1-05-03: Neuronal effects of progranulin deficiency contribute to frontotemporal dementia independent of neuroinflammation Alzheimer's & Dementia. 8: P93-P93. DOI: 10.1016/J.Jalz.2012.05.228  0.01
2011 Harris C, Herker E, Farese RV, Ott M. Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis. The Journal of Biological Chemistry. 286: 42615-25. PMID 21984835 DOI: 10.1074/Jbc.M111.285148  0.01
2011 Krahmer N, Guo Y, Wilfling F, Hilger M, Lingrell S, Heger K, Newman HW, Schmidt-Supprian M, Vance DE, Mann M, Farese RV, Walther TC. Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Cell Metabolism. 14: 504-15. PMID 21982710 DOI: 10.1016/J.Cmet.2011.07.013  1
2011 Rosen EY, Wexler EM, Versano R, Coppola G, Gao F, Winden KD, Oldham MC, Martens LH, Zhou P, Farese RV, Geschwind DH. Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Neuron. 71: 1030-42. PMID 21943601 DOI: 10.1016/J.Neuron.2011.07.021  1
2011 Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stančáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, ... ... Farese RV, et al. SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Molecular Cell. 44: 177-90. PMID 21856199 DOI: 10.1016/J.Molcel.2011.07.019  1
2011 Monetti M, Levin MC, Watt MJ, Hubbard BK, Newgard C, Farese RV, Hevener AL, Farese RV. Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 108: E523; author reply E. PMID 21807991 DOI: 10.1073/Pnas.1108505108  1
2011 Cenik B, Sephton CF, Dewey CM, Xian X, Wei S, Yu K, Niu W, Coppola G, Coughlin SE, Lee SE, Dries DR, Almeida S, Geschwind DH, Gao FB, Miller BL, ... Farese RV, et al. Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. The Journal of Biological Chemistry. 286: 16101-8. PMID 21454553 DOI: 10.1074/Jbc.M110.193433  1
2011 Sharma N, Arias EB, Bhat AD, Sequea DA, Ho S, Croff KK, Sajan MP, Farese RV, Cartee GD. Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats. American Journal of Physiology. Endocrinology and Metabolism. 300: E966-78. PMID 21386065 DOI: 10.1152/ajpendo.00659.2010  1
2011 Kao AW, Eisenhut RJ, Martens LH, Nakamura A, Huang A, Bagley JA, Zhou P, de Luis A, Neukomm LJ, Cabello J, Farese RV, Kenyon C. A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 4441-6. PMID 21368173 DOI: 10.1073/Pnas.1100650108  1
2011 Harris CA, Haas JT, Streeper RS, Stone SJ, Kumari M, Yang K, Han X, Brownell N, Gross RW, Zechner R, Farese RV. DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes. Journal of Lipid Research. 52: 657-67. PMID 21317108 DOI: 10.1194/Jlr.M013003  1
2011 Pillai P, Desai S, Patel R, Sajan M, Farese R, Ostrov D, Acevedo-Duncan M. A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma. The International Journal of Biochemistry & Cell Biology. 43: 784-94. PMID 21315177 DOI: 10.1016/J.Biocel.2011.02.002  1
2011 Bewersdorf J, Farese RV, Walther TC. A new way to look at fat Nature Methods. 8: 132-133. PMID 21278725 DOI: 10.1038/Nmeth0211-132  1
2011 Ortmeyer HK, Sajan MP, Miura A, Kanoh Y, Rivas J, Li Y, Standaert ML, Ryan AS, Bodkin NL, Farese RV, Hansen BC. Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C. Antioxidants & Redox Signaling. 14: 207-19. PMID 20518698 DOI: 10.1089/ars.2010.3234  1
2011 Pillai P, Desai S, Patel R, Sajan M, Farese R, Ostrov D, Acevedo-Duncan M. Erratum to “A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma” [Int. J. Biochem. Cell Biol. 43 (5) (2011) 784–794] The International Journal of Biochemistry & Cell Biology. 43: 1412. DOI: 10.1016/J.Biocel.2011.05.015  0.01
2010 Herker E, Harris C, Hernandez C, Carpentier A, Kaehlcke K, Rosenberg AR, Farese RV, Ott M. Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. Nature Medicine. 16: 1295-8. PMID 20935628 DOI: 10.1038/Nm.2238  0.01
2010 Jiao J, Herl LD, Farese RV, Gao FB. MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia. Plos One. 5: e10551. PMID 20479936 DOI: 10.1371/Journal.Pone.0010551  1
2010 Sharma N, Arias EB, Sajan MP, MacKrell JG, Bhat AD, Farese RV, Cartee GD. Insulin resistance for glucose uptake and Akt2 phosphorylation in the soleus, but not epitrochlearis, muscles of old vs. adult rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 108: 1631-40. PMID 20339009 DOI: 10.1152/japplphysiol.01412.2009  1
2010 Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, ... ... Farese RV, et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature. 464: 121-5. PMID 20203611 DOI: 10.1038/Nature08778  1
2010 Sopasakis VR, Liu P, Suzuki R, Kondo T, Winnay J, Tran TT, Asano T, Smyth G, Sajan MP, Farese RV, Kahn CR, Zhao JJ. Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation. Cell Metabolism. 11: 220-30. PMID 20197055 DOI: 10.1016/J.Cmet.2010.02.002  1
2010 Koliwad SK, Streeper RS, Monetti M, Cornelissen I, Chan L, Terayama K, Naylor S, Rao M, Hubbard B, Farese RV. DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation. The Journal of Clinical Investigation. 120: 756-67. PMID 20124729 DOI: 10.1172/JCI36066  1
2010 Farese RV, Sajan MP. Metabolic functions of atypical protein kinase C: "Good" and "bad" as defined by nutritional status American Journal of Physiology - Endocrinology and Metabolism. 298. PMID 19996389 DOI: 10.1152/ajpendo.00608.2009  1
2009 Krahmer N, Guo Y, Farese RV, Walther TC. SnapShot: Lipid Droplets Cell. 139. PMID 19945384 DOI: 10.1016/J.Cell.2009.11.023  1
2009 Farese RV, Walther TC. Lipid Droplets Finally Get a Little R-E-S-P-E-C-T Cell. 139: 855-860. PMID 19945371 DOI: 10.1016/J.Cell.2009.11.005  1
2009 Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn R, Braun U, Leitges M, Farese RV. AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC. American Journal of Physiology. Endocrinology and Metabolism. 298: E179-92. PMID 19887597 DOI: 10.1152/ajpendo.00392.2009  0.01
2009 Thaler JP, Choi SJ, Sajan MP, Ogimoto K, Nguyen HT, Matsen M, Benoit SC, Wisse BE, Farese RV, Schwartz MW. Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses. Endocrinology. 150: 5362-72. PMID 19819945 DOI: 10.1210/En.2009-0509  1
2009 Peng Y, Rideout D, Rakita S, Sajan M, Farese R, You M, Murr MM. Downregulation of adiponectin/AdipoR2 is associated with steatohepatitis in obese mice. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 13: 2043-9. PMID 19763702 DOI: 10.1007/S11605-009-1032-2  1
2009 Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AY, Farese RV, Wang JC. Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. The Journal of Biological Chemistry. 284: 25593-601. PMID 19628874 DOI: 10.1074/Jbc.M109.025452  1
2009 Guo S, Copps KD, Dong X, Park S, Cheng Z, Pocai A, Rossetti L, Sajan M, Farese RV, White MF. The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis. Molecular and Cellular Biology. 29: 5070-83. PMID 19596788 DOI: 10.1128/Mcb.00138-09  1
2009 Villanueva CJ, Monetti M, Shih M, Zhou P, Watkins SM, Bhanot S, Farese RV. Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids. Hepatology (Baltimore, Md.). 50: 434-42. PMID 19472314 DOI: 10.1002/hep.22980  1
2009 Sajan MP, Standaert ML, Rivas J, Miura A, Kanoh Y, Soto J, Taniguchi CM, Kahn CR, Farese RV. Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFκB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance Diabetologia. 52: 1197-1207. PMID 19357831 DOI: 10.1007/S00125-009-1336-5  1
2009 Yen CL, Cheong ML, Grueter C, Zhou P, Moriwaki J, Wong JS, Hubbard B, Marmor S, Farese RV. Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Nature Medicine. 15: 442-6. PMID 19287392 DOI: 10.1038/nm.1937  1
2009 Guo Y, Cordes KR, Farese RV, Walther TC. Lipid droplets at a glance Journal of Cell Science. 122: 749-752. PMID 19261844 DOI: 10.1242/Jcs.037630  1
2009 Sajan MP, Standaert ML, Nimal S, Varanasi U, Pastoor T, Mastorides S, Braun U, Leitges M, Farese RV. The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity. Journal of Lipid Research. 50: 1133-45. PMID 19202134 DOI: 10.1194/jlr.M800520-JLR200  1
2009 Stone SJ, Levin MC, Zhou P, Han J, Walther TC, Farese RV. The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. The Journal of Biological Chemistry. 284: 5352-61. PMID 19049983 DOI: 10.1074/Jbc.M805768200  1
2009 Walther TC, Farese RV. The life of lipid droplets Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1791: 459-466. PMID 19041421 DOI: 10.1016/J.Bbalip.2008.10.009  1
2009 Shih MY, Kane MA, Zhou P, Yen CL, Streeper RS, Napoli JL, Farese RV. Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin. The Journal of Biological Chemistry. 284: 4292-9. PMID 19028692 DOI: 10.1074/Jbc.M807503200  1
2008 Temofonte N, Sajan MP, Nimal S, Pastoor T, Fumero C, Casaubon L, Powe JL, Standaert ML, Farese RV. Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle. Diabetologia. 52: 60-4. PMID 18972094 DOI: 10.1007/s00125-008-1180-z  0.01
2008 Yen CL, Stone SJ, Koliwad S, Harris C, Farese RV. Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis. Journal of Lipid Research. 49: 2283-301. PMID 18757836 DOI: 10.1194/jlr.R800018-JLR200  1
2008 Minehira K, Young SG, Villanueva CJ, Yetukuri L, Oresic M, Hellerstein MK, Farese RV, Horton JD, Preitner F, Thorens B, Tappy L. Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. Journal of Lipid Research. 49: 2038-44. PMID 18515909 DOI: 10.1194/jlr.M800248-JLR200  1
2008 Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, Terayama K, Wong JS, Vale RD, Walter P, Farese RV. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature. 453: 657-61. PMID 18408709 DOI: 10.1038/Nature06928  1
2008 Peng Y, Rideout DA, Rakita SS, Sajan M, Farese R, You M, Murr MM. 569 Downregulation of Adiponectin /Adipor2 Is Associated with Hepatic Inflammation and Steatosis in Obese Mice Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63987-6  1
2007 Levin MC, Monetti M, Watt MJ, Sajan MP, Stevens RD, Bain JR, Newgard CB, Farese RV, Farese RV. Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle. American Journal of Physiology. Endocrinology and Metabolism. 293: E1772-81. PMID 17940217 DOI: 10.1152/Ajpendo.00158.2007  1
2007 Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, ... ... Farese RV, et al. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Molecular and Cellular Biology. 27: 8807-14. PMID 17923681 DOI: 10.1128/Mcb.01636-07  1
2007 Chan LC, Peters W, Xu Y, Chun J, Farese RV, Cases S. LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA). Journal of Leukocyte Biology. 82: 1193-200. PMID 17709403 DOI: 10.1189/jlb.0407221  1
2007 Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WR, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M. Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes. The Journal of Clinical Investigation. 117: 2289-301. PMID 17641777 DOI: 10.1172/JCI31408  1
2007 Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV, Hevener AL, Farese RV. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metabolism. 6: 69-78. PMID 17618857 DOI: 10.1016/J.Cmet.2007.05.005  1
2007 Frøsig C, Sajan MP, Maarbjerg SJ, Brandt N, Roepstorff C, Wojtaszewski JF, Kiens B, Farese RV, Richter EA. Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle. The Journal of Physiology. 582: 1289-301. PMID 17540697 DOI: 10.1113/jphysiol.2007.136614  1
2007 Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WR, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M. Muscle-specific knockout of PKC-λ impairs glucose transport and induces metabolic and diabetic syndromes Journal of Clinical Investigation. 117: 3141-3141. DOI: 10.1172/Jci31408C1  0.01
2006 Stone SJ, Levin MC, Farese RV. Membrane topology and identification of key functional amino acid residues of murine Acyl-CoA:diacylglycerol acyltransferase-2 Journal of Biological Chemistry. 281: 40273-40282. PMID 17035227 DOI: 10.1074/jbc.M607986200  1
2006 Feldman BJ, Streeper RS, Farese RV, Yamamoto KR. Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects. Proceedings of the National Academy of Sciences of the United States of America. 103: 15675-80. PMID 17030820 DOI: 10.1073/Pnas.0607501103  1
2006 Casaubon L, Sajan MP, Rivas J, Powe JL, Standaert ML, Farese RV. Contrasting insulin dose-dependent defects in activation of atypical protein kinase C and protein kinase B/Akt in muscles of obese diabetic humans. Diabetologia. 49: 3000-8. PMID 17028898 DOI: 10.1007/s00125-006-0471-5  0.01
2006 Farese RV. The nine lives of ACAT inhibitors Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1684-1686. PMID 16857957 DOI: 10.1161/01.ATV.0000227511.35456.90  1
2006 Rudel LL, Farese RV. ACAT inhibition and the progression of coronary atherosclerosis. The New England Journal of Medicine. 354: 2616-7; author reply. PMID 16775245 DOI: 10.1056/Nejmc061094  1
2006 Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR. Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta. Cell Metabolism. 3: 343-53. PMID 16679292 DOI: 10.1016/J.Cmet.2006.04.005  1
2006 Yen CLE, Farese RV. Fat breakdown: A function for CGI-58 (ABHD5) provides a new piece of the puzzle Cell Metabolism. 3: 305-307. PMID 16679288 DOI: 10.1016/j.cmet.2006.04.001  1
2006 Sajan MP, Rivas J, Li P, Standaert ML, Farese RV. Repletion of atypical protein kinase C following RNA interference-mediated depletion restores insulin-stimulated glucose transport Journal of Biological Chemistry. 281: 17466-17473. PMID 16644736 DOI: 10.1074/jbc.M510803200  1
2006 Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, et al. FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. The Journal of Biological Chemistry. 281: 10105-17. PMID 16492665 DOI: 10.1074/Jbc.M600272200  1
2006 Luna V, Casauban L, Sajan MP, Gomez-Daspet J, Powe JL, Miura A, Rivas J, Standaert ML, Farese RV. Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO4)3 in muscle of diabetic subjects. Diabetologia. 49: 375-82. PMID 16395615 DOI: 10.1007/s00125-005-0112-4  0.01
2005 Longnus SL, Ségalen C, Giudicelli J, Sajan MP, Farese RV, Van Obberghen E. Insulin signalling downstream of protein kinase B is potentiated by 5'AMP-activated protein kinase in rat hearts in vivo. Diabetologia. 48: 2591-601. PMID 16283248 DOI: 10.1007/s00125-005-0016-3  0.01
2005 Farese RV, Sajan MP, Standaert ML. Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): Actions and defects in obesity and type II diabetes Experimental Biology and Medicine. 230: 593-605. PMID 16179727  1
2005 Lee S, Nakamura E, Yang H, Wei W, Linggi MS, Sajan MP, Farese RV, Freeman RS, Carter BD, Kaelin WG, Schlisio S. Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer. Cancer Cell. 8: 155-67. PMID 16098468 DOI: 10.1016/J.Ccr.2005.06.015  1
2005 Farese RV, Sajan MP, Standaert ML. Atypical protein kinase C in insulin action and insulin resistance Biochemical Society Transactions. 33: 350-353. PMID 15787604 DOI: 10.1042/BST0330350  1
2005 Chen HC, Farese RV. Inhibition of triglyceride synthesis as a treatment strategy for obesity: Lessons from DGAT1-deficient mice Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 482-486. PMID 15569818 DOI: 10.1161/01.ATV.0000151874.81059.ad  1
2005 Yen CLE, Monetti M, Burri BJ, Farese RV. The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters Journal of Lipid Research. 46: 1502-1511. DOI: 10.1194/jlr.M500036-JLR200  1
2004 Beeson M, Sajan MP, Daspet JG, Luna V, Dizon M, Grebenev D, Powe JL, Lucidi S, Miura A, Kanoh Y, Bandyopadhyay G, Standaert ML, Yeko TR, Farese RV. Defective Activation of Protein Kinase C-z in Muscle by Insulin and Phosphatidylinositol-3,4,5,-(PO(4))(3) in Obesity and Polycystic Ovary Syndrome. Metabolic Syndrome and Related Disorders. 2: 49-56. PMID 18370676 DOI: 10.1089/met.2004.2.49  1
2004 Miura A, Sajan MP, Standaert ML, Bandyopadhyay G, Kahn CR, Farese RV. Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes. Biochemistry. 43: 15503-15509. PMID 15581362 DOI: 10.1021/Bi049221Y  1
2004 Standaert ML, Sajan MP, Miura A, Bandyopadhyay G, Farese RV. Requirements for pYXXM motifs in Cbl for binding to the p85 subunit of phosphatidylinositol 3-kinase and Crk, and activation of atypical protein kinase C and glucose transport during insulin action in 3T3/L1 adipocytes Biochemistry. 43: 15494-15502. PMID 15581361 DOI: 10.1021/bi049222q  1
2004 Richter EA, Vistisen B, Maarbjerg SJ, Sajan M, Farese RV, Kiens B. Differential effect of bicycling exercise intensity on activity and phosphorylation of atypical protein kinase C and extracellular signal-regulated protein kinase in skeletal muscle. The Journal of Physiology. 560: 909-18. PMID 15297577 DOI: 10.1113/jphysiol.2004.071373  0.01
2004 Sajan MP, Standaert ML, Miura A, Bandyopadhyay G, Vollenweider P, Franklin DM, Lea-Currie R, Farese RV. Impaired activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 in cultured preadipocyte-derived adipocytes and myotubes of obese subjects. The Journal of Clinical Endocrinology and Metabolism. 89: 3994-8. PMID 15292339 DOI: 10.1210/JC.2004-0106  0.01
2004 Sajan MP, Standaert ML, Miura A, Kahn CR, Farese RV. Tissue-specific differences in activation of atypical protein kinase C and protein kinase B in muscle, liver, and adipocytes of insulin receptor substrate-1 knockout mice Molecular Endocrinology. 18: 2513-2521. PMID 15256535 DOI: 10.1210/me.2004-0045  1
2004 Chen HC, Rao M, Sajan MP, Standaert M, Kanoh Y, Miura A, Farese RV. Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking acyl CoA: diacylglycerol acyltransferase 1 Diabetes. 53: 1445-1451. PMID 15161747 DOI: 10.2337/diabetes.53.6.1445  1
2004 Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver: Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states Journal of Biological Chemistry. 279: 24929-24934. PMID 15069067 DOI: 10.1074/jbc.M402440200  1
2004 Miura A, Sajan MP, Standaert ML, Bandyopadhyay G, Franklin DM, Lea-Currie R, Farese RV. Cbl PYXXM motifs activate the P85 subunit of phosphatidylinositol 3-kinase, Crk, atypical protein kinase C, and glucose transport during thiazolidinedione action in 3T3/L1 and human adipocytes. Biochemistry. 42: 14335-41. PMID 14640702 DOI: 10.1021/BI034808I  0.01
2004 Tagliapietra F, Farese R, Busetto M. Test of a deployment control software for a space tether using a hardware emulator International Astronautical Federation - 55th International Astronautical Congress 2004. 2: 768-776.  1
2003 Nielsen JN, Frøsig C, Sajan MP, Miura A, Standaert ML, Graham DA, Wojtaszewski JFP, Farese RV, Richter EA. Increased atypical PKC activity in endurance-trained human skeletal muscle Biochemical and Biophysical Research Communications. 312: 1147-1153. PMID 14651992 DOI: 10.1016/j.bbrc.2003.11.041  1
2003 Bandyopadhyay G, Standaert ML, Sajan MP, Kanoh Y, Miura A, Braun U, Kruse F, Leitges M, Farese RV. Protein kinase C-lambda knockout in embryonic stem cells and adipocytes impairs insulin-stimulated glucose transport. Molecular Endocrinology (Baltimore, Md.). 18: 373-83. PMID 14615604 DOI: 10.1210/ME.2003-0087  0.01
2003 Gower WR, San Miguel GI, Carter GM, Hassan I, Farese RV, Vesely DL. Atrial natriuretic hormone prohormone gene expression in cardiac and extra-cardiac tissues of diabetic Goto-Kakizaki rats. Molecular and Cellular Biochemistry. 252: 263-71. PMID 14577601 DOI: 10.1023/A:1025552029296  1
2003 Beeson M, Sajan MP, Dizon M, Grebenev D, Gomez-Daspet J, Miura A, Kanoh Y, Powe J, Bandyopadhyay G, Standaert ML, Farese RV. Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise. Diabetes. 52: 1926-34. PMID 12882907 DOI: 10.2337/DIABETES.52.8.1926  0.01
2003 Yen CLE, Farese RV. MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine Journal of Biological Chemistry. 278: 18532-18537. PMID 12621063 DOI: 10.1074/jbc.M301633200  1
2003 Kanoh Y, Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Farese RV. Defective activation of atypical protein kinase C zeta and lambda by insulin and phosphatidylinositol-3,4,5-(PO4)(3) in skeletal muscle of rats following high-fat feeding and streptozotocin-induced diabetes. Endocrinology. 144: 947-54. PMID 12586772 DOI: 10.1210/EN.2002-221017  0.01
2003 Arribas M, Valverde AM, Burks D, Klein J, Farese RV, White MF, Benito M. Essential role of protein kinase C zeta in the impairment of insulin-induced glucose transport in IRS-2-deficient brown adipocytes. Febs Letters. 536: 161-6. PMID 12586357 DOI: 10.1016/S0014-5793(03)00049-8  1
2002 Standaert ML, Ortmeyer HK, Sajan MP, Kanoh Y, Bandyopadhyay G, Hansen BC, Farese RV. Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota. Diabetes. 51: 2936-43. PMID 12351430 DOI: 10.2337/DIABETES.51.10.2936  1
2002 Chen HC, Ladha Z, Farese RV. Deficiency of Acyl coenzyme a:Diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models Endocrinology. 143: 2893-2898. PMID 12130553 DOI: 10.1210/en.143.8.2893  1
2002 Chen HC, Farese RV. Fatty acids, triglycerides, and glucose metabolism: Recent insights from knockout mice Current Opinion in Clinical Nutrition and Metabolic Care. 5: 359-363. PMID 12107369 DOI: 10.1097/00075197-200207000-00002  1
2002 Farese RV. Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states American Journal of Physiology - Endocrinology and Metabolism. 283. PMID 12067836  1
2002 Chen HC, Farese RV. Determination of adipocyte size by computer image analysis Journal of Lipid Research. 43: 986-989. PMID 12032175  1
2002 Chen HC, Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert M, Farese RV. Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-β-D-riboside (AICAR)-stimulated glucose transport Journal of Biological Chemistry. 277: 23554-23562. PMID 11978788 DOI: 10.1074/jbc.M201152200  1
2002 Standaert ML, Kanoh Y, Sajan MP, Bandyopadhyay G, Farese RV. Cbl, IRS-1, and IRS-2 mediate effects of rosiglitazone on PI3K, PKC-λ, and glucose transport in 3T3/L1 adipocytes Endocrinology. 143: 1705-1716. PMID 11956152 DOI: 10.1210/en.143.5.1705  1
2002 Leitges M, Plomann M, Standaert ML, Bandyopadhyay G, Sajan MP, Kanoh Y, Farese RV, Letiges M. Knockout of PKC alpha enhances insulin signaling through PI3K. Molecular Endocrinology (Baltimore, Md.). 16: 847-58. PMID 11923480 DOI: 10.1210/MEND.16.4.0809  0.01
2002 Sajan MP, Bandyopadhyay G, Kanoh Y, Standaert ML, Quon MJ, Reed BC, Dikic I, Farese RV. Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D. The Biochemical Journal. 362: 665-74. PMID 11879194 DOI: 10.1042/0264-6021:3620665  1
2002 Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert ML, Quon MJ, Lea-Currie R, Sen A, Farese RV. PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes. The Journal of Clinical Endocrinology and Metabolism. 87: 716-23. PMID 11836310 DOI: 10.1210/jcem.87.2.8252  1
2001 Buhman KK, Chen HC, Farese RV. The Enzymes of Neutral Lipid Synthesis Journal of Biological Chemistry. 276: 40369-40372. PMID 11544264 DOI: 10.1074/jbc.R100050200  1
2001 Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert ML, Quon MJ, Reed BC, Dikic I, Farese RV. Glucose activates protein kinase C-zeta /lambda through proline-rich tyrosine kinase-2, extracellular signal-regulated kinase, and phospholipase D: a novel mechanism for activating glucose transporter translocation. The Journal of Biological Chemistry. 276: 35537-45. PMID 11463795 DOI: 10.1074/Jbc.M106042200  1
2001 Farese RV. Insulin-sensitive phospholipid signaling systems and glucose transport. Update II Experimental Biology and Medicine. 226: 283-295. PMID 11368419  1
2001 Kanoh Y, Bandyopadhyay G, Sajan MP, Standaert ML, Farese RV. Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-ζ/λ by insulin in vastus lateralis muscles and adipocytes of diabetic rats Endocrinology. 142: 1595-1605. PMID 11250941 DOI: 10.1210/en.142.4.1595  1
2001 Standaert ML, Bandyopadhyay G, Kanoh Y, Sajan MP, Farese RV. Insulin and PIP3 activate PKC-ζ by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites Biochemistry. 40: 249-255. PMID 11141077 DOI: 10.1021/bi0018234  1
2000 Chen HC, Farese RV. DGAT and triglyceride synthesis: A new target for obesity treatment? Trends in Cardiovascular Medicine. 10: 188-192. PMID 11282293 DOI: 10.1016/S1050-1738(00)00066-9  1
2000 Buhman KF, Accad M, Farese RV. Mammalian acyl-CoA:cholesterol acyltransferases Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1529: 142-154. PMID 11111084 DOI: 10.1016/S1388-1981(00)00144-X  1
2000 Bandyopadhyay G, Kanoh Y, Sajan MP, Standaert ML, Farese RV. Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-λ on insulin-stimulated glucose transport in L6 myotubes Endocrinology. 141: 4120-4127. PMID 11089544  1
2000 Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert ML, Burke TR, Quon MJ, Reed BC, Dikic I, Noel LE, Newgard CB, Farese R. Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter. The Journal of Biological Chemistry. 275: 40817-26. PMID 11007796 DOI: 10.1074/Jbc.M007920200  1
2000 Farese RV, Cases S, Smith SJ. Triglyceride synthesis: Insights from the cloning of diacylglycerol acyltransferase Current Opinion in Lipidology. 11: 229-234. PMID 10882337 DOI: 10.1097/00041433-200006000-00002  1
2000 Kanoh Y, Bandyopadhyay G, Sajan MP, Standaert ML, Farese RV. Thiazolidinedione treatment enhances insulin effects on protein kinase C-ζ/λ activation and glucose transport in adipocytes of nondiabetic and Goto-Kakizaki type II diabetic rats Journal of Biological Chemistry. 275: 16690-16696. PMID 10749857 DOI: 10.1074/jbc.M000287200  1
1999 Sajan MP, Standaert ML, Bandyopadhyay G, Quon MJ, Burke TR, Farese RV. Protein kinase C-zeta and phosphoinositide-dependent protein kinase-1 are required for insulin-induced activation of ERK in rat adipocytes. The Journal of Biological Chemistry. 274: 30495-500. PMID 10521430 DOI: 10.1074/jbc.274.43.30495  0.01
1999 Bandyopadhyay G, Standaert ML, Sajan MP, Karnitz LM, Cong L, Quon MJ, Farese RV. Dependence of insulin-stimulated glucose transporter 4 translocation on 3-phosphoinositide-dependent protein kinase-1 and its target threonine-410 in the activation loop of protein kinase C-zeta. Molecular Endocrinology (Baltimore, Md.). 13: 1766-72. PMID 10517677 DOI: 10.1210/MEND.13.10.0364  0.01
1999 Chen HC, Farese RV. Steroid hormones: Interactions with membrane-bound receptors Current Biology. 9. PMID 10395533 DOI: 10.1016/S0960-9822(99)80300-5  1
1999 Vesely DL, Gower WR, Dietz JR, Overton RM, Clark LC, Antwi EK, Farese RV. Elevated atrial natriuretic peptides and early renal failure in type 2 diabetic Goto-Kakizaki rats. Metabolism: Clinical and Experimental. 48: 771-8. PMID 10381153 DOI: 10.1016/S0026-0495(99)90178-6  1
1999 Standaert ML, Bandyopadhyay G, Sajan MP, Cong L, Quon MJ, Farese RV. Okadaic acid activates atypical protein kinase C (zeta/lambda) in rat and 3T3/L1 adipocytes. An apparent requirement for activation of Glut4 translocation and glucose transport. The Journal of Biological Chemistry. 274: 14074-8. PMID 10318822 DOI: 10.1074/JBC.274.20.14074  0.01
1999 Schrot RJ, Foulis PR, Morrison AD, Farese RV. A computerized model for home glucose monitoring proficiency testing: Efficacy of an innovative testing program Diabetes Educator. 25: 48-55. PMID 10232180  1
1999 Standaert ML, Bandyopadhyay G, Antwi EK, Farese RV. RO 31-8220 activates c-Jun N-terminal kinase and glycogen synthase in rat adipocytes and L6 myotubes. Comparison to actions of insulin Endocrinology. 140: 2145-2151. PMID 10218965  1
1999 Herz J, Farese RV. The LDL receptor gene family, apolipoprotein B and cholesterol in embryonic development Journal of Nutrition. 129. PMID 10064312 DOI: 10.1093/Jn/129.2.473S  1
1999 BANDYOPADHYAY G, STANDAERT ML, KIKKAWA U, ONO Y, MOSCAT J, FARESE RV. Effects of transiently expressed atypical (ζ, λ), conventional (α, β) and novel (δ, ε) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific interchangeable effects of protein kinases C-ζ and C-λ Biochemical Journal. 337: 461. DOI: 10.1042/0264-6021:3370461  0.01
1998 Accad M, Farese RV. Cholesterol homeostasis: A role for oxysterols Current Biology. 8. PMID 9742388  1
1998 Farese RV. Acyl CoA:cholesterol acyltransferase genes and knockout mice Current Opinion in Lipidology. 9: 119-123. PMID 9559268 DOI: 10.1097/00041433-199804000-00007  1
1998 Farese RV, Herz J. Cholesterol metabolism and embryogenesis Trends in Genetics. 14: 115-120. PMID 9540409 DOI: 10.1016/S0168-9525(97)01377-2  1
1998 Standaert M, Bandyopadhyay G, Galloway L, Ono Y, Mukai H, Farese R. Comparative effects of GTPγS and insulin on the activation of Rho, phosphatidylinositol 3-kinase, and protein kinase N in Rat adipocytes. Relationship to glucose transport Journal of Biological Chemistry. 273: 7470-7477. PMID 9516446 DOI: 10.1074/Jbc.273.13.7470  1
1997 Khovidhunkit W, Farese RV. Resolution of propylthiouracil-induced hepatic failure after treatment of thyrotoxicosis. The Western Journal of Medicine. 167: 353-6. PMID 9392993  1
1997 Standaert ML, Galloway L, Karnam P, Bandyopadhyay G, Moscat J, Farese RV. Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport. The Journal of Biological Chemistry. 272: 30075-82. PMID 9374484 DOI: 10.1074/jbc.272.48.30075  0.01
1997 Bandyopadhyay G, Standaert ML, Galloway L, Moscat J, Farese RV. Evidence for involvement of protein kinase C (PKC)-ζ and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes Endocrinology. 138: 4721-4731. PMID 9348199 DOI: 10.1210/en.138.11.4721  1
1997 Karnam P, Standaert ML, Galloway L, Farese RV. Activation and translocation of Rho (and ADP ribosylation factor) by insulin in rat adipocytes: Apparent involvement of phosphatidylinositol 3- kinase Journal of Biological Chemistry. 272: 6136-6140. PMID 9045624 DOI: 10.1074/jbc.272.10.6136  1
1996 Avignon A, Yamada K, Zhou X, Spencer B, Cardona O, Saba-Siddique S, Galloway L, Standaert ML, Farese RV. Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis. Diabetes. 45: 1396-404. PMID 8826977 DOI: 10.2337/diab.45.10.1396  1
1996 Farese RV. Insulin-sensitive phospholipid signaling systems and glucose transport: An update Proceedings of the Society For Experimental Biology and Medicine. 213: 1-12. PMID 8820818  1
1996 Standaert ML, Bandyopadhyay G, Zhou X, Galloway L, Farese RV. Insulin stimulates phospholipase D-dependent phosphatidylcholine hydrolysis, Rho translocation, de novo phospholipid synthesis, and diacylglycerol/protein kinase C signaling in L6 myotubes Endocrinology. 137: 3014-3020. PMID 8770926 DOI: 10.1210/en.137.7.3014  1
1996 Standaert ML, Bandyopadhyay G, Galloway L, Farese RV. Effects of phorbol esters on insulin-induced activation of phosphatidylinositol 3-kinase, glucose transport, and glycogen synthase in rat adipocytes Febs Letters. 388: 26-28. PMID 8654582 DOI: 10.1016/0014-5793(96)00492-9  1
1996 Standaert ML, Avignon A, Yamada K, Bandyopadhyay G, Farese RV. The phosphatidylinositol 3-kinase inhibitor, wortmannin, inhibits insulin-induced activation of phosphatidylcholine hydrolysis and associated protein kinase C translocation in rat adipocytes Biochemical Journal. 313: 1039-1046. PMID 8611143  1
1996 Standaert ML, Bandyopadhyay G, Galloway L, Farese RV. Dissociation of MAP kinase activation from insulin-induced regulation of glycogen synthase in rat adipocytes and L-6 myotubes Journal of Investigative Medicine. 44.  1
1995 Avignon A, Standaert ML, Yamada K, Mischak H, Spencer B, Farese RV. Insulin increases mRNA levels of protein kinase C-alpha and -beta in rat adipocytes and protein kinase C-alpha, -beta and -theta in rat skeletal muscle. The Biochemical Journal. 308: 181-7. PMID 7755564 DOI: 10.1042/BJ3080181  1
1995 Yamada K, Avignon A, Standaert ML, Cooper DR, Spencer B, Farese RV. Effects of insulin on the translocation of protein kinase C-theta and other protein kinase C isoforms in rat skeletal muscles. The Biochemical Journal. 308: 177-80. PMID 7755563 DOI: 10.1042/BJ3080177  1
1995 Standaert ML, Bandyopadhyay G, Farese RV. Studies with wortmannin suggest a role for phosphatidylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: Comparison of insulin and protein kinase C modulators Biochemical and Biophysical Research Communications. 209: 1082-1088. PMID 7733962 DOI: 10.1006/bbrc.1995.1608  1
1994 Farese RV, Standaert ML, Arnold TP, Yamada K, Musunuru K, Hernandez H, Mischak H, Cooper DR. Preferential activation of microsomal diacylglycerol/protein kinase C signaling during glucose treatment (De Novo phospholipid synthesis) of rat adipocytes. The Journal of Clinical Investigation. 93: 1894-9. PMID 8182122 DOI: 10.1172/JCI117180  0.01
1994 Yamada K, Standaert ML, Yu B, Mischak H, Cooper DR, Farese RV. Insulin-like effects of sodium orthovanadate on diacylglycerol-protein kinase C signaling in BC3H-1 myocytes. Archives of Biochemistry and Biophysics. 312: 167-72. PMID 8031124 DOI: 10.1006/ABBI.1994.1295  0.01
1994 Zhao L, Standaert ML, Cooper DR, Avignon A, Farese RV. Effects of Insulin on Protein Kinase-C (PKC) in HIRC-B Cells: Specific Activation of PKCe and Its Resistance to Phorbol Ester-Induced Down-Regulation Endocrinology. 135: 2504-2510. PMID 7988438  1
1994 Farese RV, Standaert ML, Yamada K, Huang LC, Zhang C, Cooper DR, Wang Z, Yang Y, Suzuki S, Toyota T. Insulin-induced activation of glycerol-3-phosphate acyltransferase by a chiro-inositol-containing insulin mediator is defective in adipocytes of insulin-resistant, type II diabetic, Goto-Kakizaki rats. Proceedings of the National Academy of Sciences of the United States of America. 91: 11040-4. PMID 7972005 DOI: 10.1073/pnas.91.23.11040  1
1994 Standaert ML, Musunuru K, Yamada K, Cooper DR, Farese RV. Insulin-stimulated phosphatidylcholine hydrolysis, diacylglycerol/protein kinase C signalling, and hexose transport in pertussis toxin-treated BC3H-1 myocytes Cellular Signalling. 6: 707-716. PMID 7857772 DOI: 10.1016/0898-6568(94)90052-3  1
1994 Villar-Palasi C, Farese RV. Impaired skeletal muscle glycogen synthase activation by insulin in the Goto-Kakizaki (G/K) rat Diabetologia. 37: 885-888. PMID 7806017 DOI: 10.1007/BF00400943  1
1993 Linton MF, Farese RV, Young SG. Familial hypobetalipoproteinemia Journal of Lipid Research. 34: 521-541. PMID 8496659  1
1993 Ishizuka T, Yamamoto M, Kajita K, Yasuda K, Miura K, Hernandez H, Farese RV. Differential effect of aging on protein kinase C activity in rat adipocytes and soleus muscle. Metabolism: Clinical and Experimental. 42: 420-5. PMID 8487663 DOI: 10.1016/0026-0495(93)90097-8  0.01
1993 Standaert ML, Cooper DR, Hernandez H, Arnold TP, Farese RV. Differential down-regulation of insulin-sensitive protein kinase-C isoforms by 12-O-tetradecanoylphorbol-13-acetate in rat adipocytes and BC3H- 1 myocytes Endocrinology. 132: 689-692. PMID 8425487 DOI: 10.1210/en.132.2.689  1
1993 Farese RV, Standaert M, Yu B, Hernandez H, Cooper DR. 2-Hydroxypropyl-β-cyclodextrin enhances phorbol ester effects on glucose transport and/or protein kinase C-β translocation to the plasma membrane in rat adipocytes and soleus muscles Journal of Biological Chemistry. 268: 19949-19955. PMID 8376357  1
1993 Yang Y, Farese RV. Insulin activates myelin basic protein (p42 MAP) kinase by a protein kinase C-independent pathway in rat adipocytes. Dissociation from glucose transport Febs Letters. 333: 287-290. PMID 8224195 DOI: 10.1016/0014-5793(93)80672-H  1
1993 Arnold TP, Standaert ML, Hernandez H, Watson J, Mischak H, Kazanietz MG, Zhao L, Cooper DR, Farese RV. Effects of insulin and phorbol esters on MARCKS (myristoylated alanine-rich C-kinase substrate) phosphorylation (and other parameters of protein kinase C activation) in rat adipocytes, rat soleus muscle and BC3H-1 myocytes. The Biochemical Journal. 155-64. PMID 8216211 DOI: 10.1042/BJ2950155  0.01
1992 Farese RV, Linton MF, Young SG. Apolipoprotein B gene mutations affecting cholesterol levels Journal of Internal Medicine. 231: 643-652. PMID 1619387  1
1992 Farese RV, Standaert ML, Arnold T, Yu B, Ishizuka T, Hoffman J, Vila M, Cooper DR. The role of protein kinase C in insulin action. Cellular Signalling. 4: 133-43. PMID 1616820 DOI: 10.1016/0898-6568(92)90077-L  0.01
1992 Yu B, Standaert M, Arnold T, Hernandez H, Watson J, Ways K, Cooper DR, Farese RV. Effects of insulin on diacylglycerol/protein kinase-C signalling and glucose transport in rat skeletal muscles in vivo and in vitro. Endocrinology. 130: 3345-55. PMID 1597146 DOI: 10.1210/ENDO.130.6.1597146  0.01
1992 Messina JL, Standaert ML, Ishizuka T, Weinstock RS, Farese RV. Role of protein kinase C in insulin's regulation of c-fos transcription Journal of Biological Chemistry. 267: 9223-9228. PMID 1577756  1
1992 Ishizuka T, Yamamoto M, Kajita K, Nagashima T, Yasuda K, Miura K, Cooper DR, Farese RV. Insulin stimulates novel protein kinase C in rat adipocytes. Biochemical and Biophysical Research Communications. 183: 814-20. PMID 1550587 DOI: 10.1016/0006-291X(92)90556-Z  0.01
1992 Farese RV, Standaert ML, Cooper DR. Protein kinase C downregulation? [12] Nature. 360: 305. PMID 1448147 DOI: 10.1038/360305C0  1
1992 Farese RV, Standaert ML, Francois AJ, Ways K, Arnold TP, Hernandez H, Cooper DR. Effects of insulin and phorbol esters on subcellular distribution of protein kinase C isoforms in rat adipocytes. The Biochemical Journal. 319-23. PMID 1445277 DOI: 10.1042/BJ2880319  0.01
1992 Cooper DR, Watson JE, Hernandez H, Yu B, Standaert ML, Ways DK, Arnold TT, Ishizuka T, Farese RV. Direct evidence for protein kinase C involvement in insulin-stimulated hexose uptake. Biochemical and Biophysical Research Communications. 188: 142-8. PMID 1417838 DOI: 10.1016/0006-291X(92)92361-Z  0.01
1992 Farese RV, Flynn LM, Young SG. Modification of the apolipoprotein B gene in HepG2 cells by gene targeting Journal of Clinical Investigation. 90: 256-261. PMID 1321843  1
1991 Hoffman JM, Ishizuka T, Farese RV. Interrelated effects of insulin and glucose on diacylglycerol-protein kinase-C signalling in rat adipocytes and solei muscle in vitro and in vivo in diabetic rats Endocrinology. 128: 2937-2948. PMID 2036970  1
1991 Standaert ML, Sasse J, Cooper DR, Farese RV. Protein kinase C(19-31) pseudosubstrate inhibition of insulin action in rat adipocytes Febs Letters. 282: 139-142. PMID 2026249 DOI: 10.1016/0014-5793(91)80463-D  1
1991 Hoffman JM, Standaert ML, Nair GP, Farese RV. Differential effects of pertussis toxin on insulin-stimulated phosphatidylcholine hydrolysis and glycerolipid synthesis de novo. Studies in BC3H-1 myocytes and rat adipocytes. Biochemistry. 30: 3315-22. PMID 2009269 DOI: 10.1021/BI00227A021  0.01
1991 Farese RV, Yost TJ, Eckel RH. Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans Metabolism. 40: 214-216. PMID 1988780 DOI: 10.1016/0026-0495(91)90178-Y  1
1991 Boggs KP, Farese RV, Buse MG. Insulin administration in vivo increases 1,2-diacylglycerol in rat skeletal muscle Endocrinology. 128: 636-638. PMID 1986947 DOI: 10.1210/endo-128-1-636  1
1991 Ishizuka T, Cooper DR, Arnold T, Hernandez H, Farese RV. Downregulation of protein kinase C and insulin-stimulated 2-deoxyglucose uptake in rat adipocytes by phorbol esters, glucose, and insulin Diabetes. 40: 1274-1281. PMID 1936590  1
1991 Farese RV, Ishizuka T, Standaert ML, Cooper DR. Sulfonylureas activate glucose transport and protein kinase C in rat adipocytes Metabolism. 40: 196-200. PMID 1899124 DOI: 10.1016/0026-0495(91)90174-U  1
1991 del Carmen Vila M, Farese RV. Insulin rapidly increases glycerol-3-phosphate acyltransferase activity in rat adipocytes Archives of Biochemistry and Biophysics. 284: 366-368. PMID 1846521 DOI: 10.1016/0003-9861(91)90309-7  1
1991 Farese RV, Standaert ML, Ishizuka T, Yu B, Hernandez H, Waldron C, Watson J, Farese JP, Cooper DR, Wickstrom E. Antisense DNA Downregulates Protein Kinase C Isozymes (β and α) and Insulin-Stimulated 2-Deoxyglucose Uptake in Rat Adipocytes Antisense Research and Development. 1: 35-42. PMID 1822247 DOI: 10.1089/Ard.1991.1.35  1
1990 Foster RH, Davis JS, Farese RV. External calcium is required for activation of phospholipase C by angiotensin II in adrenal glomerulosa cells Molecular and Cellular Biochemistry. 95: 157-166. PMID 2366756 DOI: 10.1007/BF00219974  1
1990 Russell DH, Zorn NE, Buckley AR, Crowe PD, Sauro MD, Hadden EM, Farese RV, Laird HE. Prolactin and known modulators of rat splenocytes activate nuclear protein kinase C. European Journal of Pharmacology. 188: 139-52. PMID 2318255 DOI: 10.1016/0922-4106(90)90049-4  1
1990 Farese RV. Lipid-Derived Mediators in Insulin Action Proceedings of the Society For Experimental Biology and Medicine. 195: 312-324. PMID 2259701 DOI: 10.3181/00379727-195-43150C  1
1990 Standaert ML, Buckley DJ, Ishizuka T, Hoffman JM, Cooper DR, Pollet RJ, Farese RV. Protein kinase C inhibitors block insulin and PMA-stimulated hexose transport in isolated rat adipocytes and BC3H-1 myocytes. Metabolism: Clinical and Experimental. 39: 1170-9. PMID 2233279 DOI: 10.1016/0026-0495(90)90090-Y  1
1990 Ishizuka T, Cooper DR, Hernandez H, Buckley D, Standaert M, Farese RV. Effects of insulin on diacylglycerol-protein kinase C signaling in rat diaphragm and soleus muscles and relationship to glucose transport. Diabetes. 39: 181-90. PMID 2227125 DOI: 10.2337/diab.39.2.181  0.01
1990 Cooper DR, Ishizuka T, Watson JE, Standaert ML, Nair G, Farese RV. Protein kinase C activation patterns are determined by methodological variations. Studies of insulin action in BC3H-1 myocytes and rat adipose tissue. Biochimica Et Biophysica Acta. 1054: 95-102. PMID 2200530 DOI: 10.1016/0167-4889(90)90210-5  0.01
1990 Ishizuka T, Cooper DR, Farese RV. Insulin provokes apparent increases in rat adipocyte M-kinase Biochemical and Biophysical Research Communications. 169: 966-972. PMID 2194457 DOI: 10.1016/0006-291X(90)91988-5  1
1990 Del C. Vila M, Milligan G, Standaert ML, Farese RV. Insulin activates glycerol-3-phosphate acyltransferase (de novo phosphatidic acid synthesis) through a phospholipid-derived mediator. Apparent involvement of Giα and activation of a phospholipase C Biochemistry. 29: 8735-8740. PMID 2176832  1
1990 Cozza EN, Vila MC, Acevedo-Duncan M, Farese RV, Gomez-Sanchez CE. Treatment of primary cultures of calf adrenal glomerulosa cells with adrenocorticotropin (ACTH) and phorbol esters: A comparative study of the effects on aldosterone production and ACTH signaling system Endocrinology. 126: 2169-2176. PMID 2156684 DOI: 10.1210/Endo-126-4-2169  1
1990 Cozza EN, del Carmen Vila M, Acevedo-Duncan M, Gomez-Sanchez CE, Farese RV. Acth increases de novo synthesis of diacylglycerol and translocates protein kinase C in primary cultures of calf adrenal glomerulosa cells Journal of Steroid Biochemistry. 35: 343-351. PMID 2155356 DOI: 10.1016/0022-4731(90)90294-3  1
1990 Farese RV, Vila MD, Standaert ML, Milligan G, Fox JA. Pertussis toxin-sensitive and -insensitive mechanisms for diacylglycerol-protein kinase C signalling during insulin action in BC3H-1 myocytes Transactions of the Association of American Physicians. 103: 195-201. PMID 2132531  1
1990 Cooper DR, Vila MC, Watson JE, Nair G, Pollet RJ, Standaert M, Farese RV. Sulfonylurea-stimulated glucose transport association with diacylglycerollike activation of protein kinase C in BC3H1 myocytes. Diabetes. 39: 1399-407. PMID 2121569 DOI: 10.2337/diab.39.11.1399  1
1990 Cooper DR, Hernandez H, Kuo JY, Farese RV. Insulin increases the synthesis of phospholipid and diacylglycerol and protein kinase C activity in rat hepatocytes Archives of Biochemistry and Biophysics. 276: 486-494. PMID 2106290 DOI: 10.1016/0003-9861(90)90749-O  1
1989 Cozza EN, Vila MC, Gomez-Sanchez CE, Farese RV. ACTH stimulates turnover of the phosphatidylinositol-glycan. Biochemical and Biophysical Research Communications. 157: 585-9. PMID 2849431 DOI: 10.1016/S0006-291X(88)80290-0  0.01
1989 Farese RV, Nair GP, Sierra CG, Standaert ML, Pollet RJ, Cooper DR. Insulin-like effects of epidermal growth factor and insulin-like growth factor-I on [3H]2-deoxyglucose uptake, diacylglycerol generation and protein kinase C activation in BC3H-1 myocytes. The Biochemical Journal. 261: 927-34. PMID 2803252 DOI: 10.1042/BJ2610927  1
1989 Ishizuka T, Hoffman J, Cooper DR, Watson JE, Pushkin DB, Farese RV. Glucose-induced synthesis of diacylglycerol de novo is associated with translocation (activation) of protein kinase C in rat adipocytes Febs Letters. 249: 234-238. PMID 2737282 DOI: 10.1016/0014-5793(89)80630-1  1
1989 Cooper DR, Watson JE, Acevedo-Duncan M, Pollet RJ, Standaert ML, Farese RV. Retention of specific protein kinase C isozymes following chronic phorbol ester treatment in BC3H-1 myocytes. Biochemical and Biophysical Research Communications. 161: 327-34. PMID 2730662 DOI: 10.1016/0006-291X(89)91600-8  1
1989 Ishizuka T, Cooper DR, Farese RV. Insulin stimulates the translocation of protein kinase C in rat adipocytes Febs Letters. 257: 337-340. PMID 2684690 DOI: 10.1016/0014-5793(89)81565-0  1
1989 Farese RV, Cooper DR. Potential role of phospholipid-signaling systems in insulin action and states of clinical insulin resistance Diabetes/Metabolism Reviews. 5: 455-474. PMID 2667929  1
1989 Vila MdC, Cooper DR, Davis JS, Standaert ML, Farese RV. Studies of in vivo phosphorylated proteins in BC3H-1 myocytes suggest that protein kinase C is involved in insulin action Febs Letters. 244: 177-180. PMID 2647517 DOI: 10.1016/0014-5793(89)81187-1  1
1989 Acevedo-Duncan M, Cooper DR, Standaert ML, Farese RV. Immunological evidence that insulin activates protein kinase C in BC3H-1 myocytes Febs Letters. 244: 174-176. PMID 2647516 DOI: 10.1016/0014-5793(89)81186-X  1
1989 Foster RH, Farese RV. Angiotensin II increases diacylglycerol in calf adrenal glomerulosa cells by activating de novo phospholipid synthesis Life Sciences. 45: 2015-2023. PMID 2557511 DOI: 10.1016/0024-3205(89)90576-6  1
1988 Standaert ML, Farese RV, Cooper DR, Pollet RJ. Insulin-induced glycerolipid mediators and the stimulation of glucose transport in BC3H-1 myocytes. The Journal of Biological Chemistry. 263: 8696-705. PMID 3288620  1
1988 Farese RV, Cooper DR, Konda TS, Nair G, Standaert ML, Davis JS, Pollet RJ. Mechanisms whereby insulin increases diacylglycerol in BC3H-1 myocytes. The Biochemical Journal. 256: 175-84. PMID 3146971 DOI: 10.1042/BJ2560175  1
1988 Farese RV. Phospholipid signaling systems in insulin action The American Journal of Medicine. 85: 36-43. PMID 3057893 DOI: 10.1016/0002-9343(88)90396-8  1
1988 Farese RV, Nair GP, Standaert ML, Cooper DR. Epidermal growth factor and insulin-like growth factor-I stimulate the hydrolysis of the insulin-sensitive phosphatidylinositol-glycan in BC3H-1 myocytes Biochemical and Biophysical Research Communications. 156: 1346-1352. PMID 3056411 DOI: 10.1016/S0006-291X(88)80780-0  1
1988 Nair GP, Standaert ML, Pollet RJ, Cooper DR, Farese RV. Effects of insulin and phorbol esters on diacylglycerol generation and synthesis and hydrolysis of phosphatidylcholine in BC3H-1 myocytes. Biochemical and Biophysical Research Communications. 154: 1345-9. PMID 3044366 DOI: 10.1016/0006-291X(88)90287-2  1
1988 Farese RV, Cooper DR, Konda TS, Nair G, Standaert ML, Pollet RJ. Insulin provokes co-ordinated increases in the synthesis of phosphatidylinositol, phosphatidylinositol phosphates and the phosphatidylinositol-glycan in BC3H-1 myocytes. The Biochemical Journal. 256: 185-8. PMID 2851976 DOI: 10.1042/BJ2560185  1
1988 Farese RV. Calcium as an intracellular mediator of hormone action: Intracellular phospholipid signaling systems American Journal of the Medical Sciences. 296: 223-230. PMID 2848420  1
1988 Farese RV, Fanjul LF, de Ruiz Galarreta CM, Davis JS, Cooper DR. ACTH increases diacylglycerol content and subcellular redistribution of protein kinase C in the rat adrenal in vivo. Life Sciences. 41: 2631-7. PMID 2826946 DOI: 10.1016/0024-3205(87)90277-3  0.01
1987 Davis JS, Weakland LL, Farese RV, West LA. Luteinizing hormone increases inositol trisphosphate and cytosolic free Ca2+ in isolated bovine luteal cells Journal of Biological Chemistry. 262: 8515-8521. PMID 3496333  1
1987 Standaert ML, Mojsilovic L, Farese RV, Pollet RJ. Phorbol ester inhibition of insulin-stimulated deoxyribonucleic acid synthesis in BC3H-1 myocytes. Endocrinology. 121: 941-7. PMID 3304983 DOI: 10.1210/endo-121-3-941  1
1987 Farese RV, Konda TS, Davis JS, Standaert ML, Pollet RJ, Cooper DR. Insulin rapidly increases diacylglycerol by activating de novo phosphatidic acid synthesis. Science (New York, N.Y.). 236: 586-9. PMID 3107122 DOI: 10.1126/SCIENCE.3107122  1
1987 Cooper DR, de Ruiz Galaretta CM, Fanjul LF, Mojsilovic L, Standaert ML, Pollet RJ, Farese RV. Insulin but not phorbol ester treatment increases phosphorylation of vinculin by protein kinase C in BC3H-1 myocytes. Febs Letters. 214: 122-6. PMID 3106082 DOI: 10.1016/0014-5793(87)80025-X  1
1987 Davis JS, Weakland LL, Weiland DA, Farese RV, West LA. Prostaglandin F2 alpha stimulates phosphatidylinositol 4,5-bisphosphate hydrolysis and mobilizes intracellular Ca2+ in bovine luteal cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 3728-32. PMID 3035550 DOI: 10.1073/PNAS.84.11.3728  0.01
1987 Farese RV. An update on the role of phospholipid metabolism in the action of steroidogenic agents Journal of Steroid Biochemistry. 27: 737-743. PMID 2826906 DOI: 10.1016/0022-4731(87)90144-0  1
1987 Cooper D, Konda T, Standaert M, Davis J, Pollet R, Farese R. Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes. Journal of Biological Chemistry. 262: 3633-3639. DOI: 10.1016/s0021-9258(18)61400-0  0.01
1987 Davis JS, Weakland LL, Farese RV, West LA. Luteinizing hormone increases inositol trisphosphate and cytosolic free Ca2+ in isolated bovine luteal cells. Journal of Biological Chemistry. 262: 8515-8521. DOI: 10.1016/s0021-9258(18)47444-3  0.01
1986 Farese RV, Rosic N, Standaert M, Babischkin J, Cooper DR, Davis JS, Pollet RJ. Further evidence implicating diacylglycerol generation and protein kinase C activation in agonist-induced increases in glucose uptake. Insulin-like effects of phenylephrine in BC3H-1 myocytes. Diabetes. 35: 951-7. PMID 3527826 DOI: 10.2337/diab.35.9.951  1
1986 Farese RV, Kuo JY, Babischkin JS, Davis JS. Insulin provokes a transient activation of phospholipase C in the rat epididymal fat pad Journal of Biological Chemistry. 261: 8589-8592. PMID 3522574  1
1986 Trimble ER, Bruzzone R, Biden TJ, Farese RV. Secretin induces rapid increases in inositol trisphosphate, cytosolic Ca2+ and diacylglycerol as well as cyclic AMP in rat pancreatic acini Biochemical Journal. 239: 257-261. PMID 3028367  1
1986 Davis JS, Weakland LL, West LA, Farese RV. Luteinizing hormone stimulates the formation of inositol trisphosphate and cyclic AMP in rat granulosa cells. Evidence for phospholipase C generated second messengers in the action of luteinizing hormone Biochemical Journal. 238: 597-604. PMID 3026357  1
1986 Davis JS, West LA, Weakland LL, Farese RV. Human chorionic gonadotropin activates the inositol 1,4,5-trisphosphate-Ca2+ intracellular signalling system in bovine luteal cells Febs Letters. 208: 287-291. PMID 3023139 DOI: 10.1016/0014-5793(86)81034-1  1
1986 Davis JS, West LA, Farese RV. Gonadotropin-releasing hormone (GnRH) rapidly stimulates the formation of inositol phosphates and diacylglycerol in rat granulosa cells: Further evidence for the involvement of Ca2+ and protein kinase C in the action of GnRH Endocrinology. 118: 2561-2571. PMID 3009164  1
1986 Farese RV, Rosic N, Babischkin J, Farese MG, Foster R, Davis JS. Dual activation of the inositol-triphosphate-calcium and cyclic nucleotide intracellular signaling systems by adrenocorticotropin in rat adrenal cells Biochemical and Biophysical Research Communications. 135: 742-748. PMID 3008743 DOI: 10.1016/0006-291X(86)90991-5  1
1986 Farese RV, DiMarco PE, Barnes DE, Sabir MA, Larson RE, Davis JS, Morrison AD. Rapid glucose-dependent increases in phosphatidic acid and phosphoinositides in rat pancreatic islets Endocrinology. 118: 1498-1503. PMID 3004919 DOI: 10.1210/ENDO-118-4-1498  1
1985 Smith JB, Smith L, Brown ER, Barnes D, Sabir MA, Davis JS, Farese RV. Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis and phosphoinositide hydrolysis and mobilizes intracellular calcium in cultured arterial muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 7812-6. PMID 6096858 DOI: 10.1073/PNAS.81.24.7812  0.01
1985 Farese RV, Davis JS, Barnes DE, Standaert ML, Babischkin JS, Hock R, Rosic NK, Pollet RJ. The de novo phospholipid effect of insulin is associated with increases in diacylglycerol, but not inositol phosphates or cytosolic Ca2+. The Biochemical Journal. 231: 269-78. PMID 3904739 DOI: 10.1042/BJ2310269  1
1985 Farese RV, Standaert ML, Barnes DE, Davis JS, Pollet RJ. Phorbol ester provokes insulin-like effects on glucose transport, amino acid uptake, and pyruvate dehydrogenase activity in BC3H-1 cultured myocytes. Endocrinology. 116: 2650-5. PMID 3158511 DOI: 10.1210/endo-116-6-2650  1
1985 Farese RV, Orchard JL, Larson RE, Sabir MA, Davis JS. Phosphatidylinositol hydrolysis and phosphatidylinositol 4′,5′-diphosphate hydrolysis are separable responses during secretagogue action in the rat pancreas Bba - Molecular Cell Research. 846: 296-304. PMID 2992607 DOI: 10.1016/0167-4889(85)90077-1  1
1984 Farese RV, Barnes DE, Davis JS, Standaert ML, Pollet RJ. Effects of insulin and protein synthesis inhibitors on phospholipid metabolism, diacylglycerol levels, and pyruvate dehydrogenase activity in BC3H-1 cultured myocytes. The Journal of Biological Chemistry. 259: 7094-100. PMID 6373768  1
1984 Farese RV, Sabir MA, Larson RE, Trudeau WL, Barnes D. The mechanism of action of insulin on phospholipid metabolism in rat adipose tissue. Requirement for protein synthesis and a carbohydrate source, and relationship to activation of pyruvate dehydrogenase Diabetes. 33: 648-655. PMID 6329860  1
1984 Farese RV, Sabir MA, Davis JS. Apparent increases in phospholipid degradation and turnover during combined treatment with protein synthesis inhibitors and adrenocorticotropin Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 793: 317-320. PMID 6324870 DOI: 10.1016/0005-2760(84)90336-9  1
1984 Farese RV, Larson RE, Davis JS. Rapid effects of angiotensin-II on polyphosphoinositide metabolism in rat adrenal glomerulosa Endocrinology. 114: 302-304. PMID 6317349  1
1984 Orchard JL, Davis JS, Larson RE, Farese RV. Effects of carbachol and pancreozymin (cholecystokinin-octapeptide) on polyphosphoinositide metabolism in the rat pancreas in vitro Biochemical Journal. 217: 281-287. PMID 6199018  1
1984 Farese RV. Phospholipids as intermediates in hormone action Molecular and Cellular Endocrinology. 35: 1-14. PMID 6143700 DOI: 10.1016/0303-7207(84)90024-8  1
1984 Farese RV. The role of the phosphatidate-phosphoinositide cycle in the action of steroidogenic hormones Endocrine Research. 10: 515-532. PMID 6100255 DOI: 10.1080/07435808409036514  1
1984 Davis JS, West LA, Farese RV. Effects of luteinizing hormone on phosphoinositide metabolism in rat granulosa cells Journal of Biological Chemistry. 259: 15028-15034. PMID 6096354  1
1984 Davis JS, West LA, Farese RV. Gonadotropin-releasing hormone rapidly alters polyphosphoinositide metabolism in rat granulosa cells Biochemical and Biophysical Research Communications. 122: 1289-1295. PMID 6089778 DOI: 10.1016/0006-291X(84)91232-4  1
1983 Davis JS, Farese RV, Clark MR. Stimulation of phospholipid synthesis by luteinizing hormone in isolated rat granulosa cells Endocrinology. 112: 2212-2214. PMID 6851948  1
1983 Davis JS, Farese RV, Clark MR. Gonadotropin-releasing hormone (GnRH) stimulates phosphatidylinositol metabolism in rat granulosa cell: Mechanism of action of GnRH Proceedings of the National Academy of Sciences of the United States of America. 80: 2049-2053. PMID 6340112  1
1983 Farese RV, Sabir MA, Larson RE, Trudeau WL. Insulin treatment acutely increases the concentration of phosphatidylserine in rat adipose tissue Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 750: 200-202. PMID 6337643 DOI: 10.1016/0005-2760(83)90221-7  1
1983 Elliott ME, Farese RV, Goodfriend TL. Effects of angiotensin II and dibutyryl cyclic adenosine monophosphate on phosphatidylinositol metabolism, 45Ca2+ fluxes, and aldosterone synthesis in bovine adrenal glomerulosa cells. Life Sciences. 33: 1771-8. PMID 6316048 DOI: 10.1016/0024-3205(83)90684-7  1
1983 Farese RV, Larson RE, Sabir MA, Gomez Sanchez CE. Effects of angiotensin II, K+, Adrenocorticotropin, serotonin, adenosine 3',5'-monophosphate, guanosine 3',5'-monophosphate, A23187, and EGTA on aldosterone synthesis and phospholipid metabolism in the rat adrenal zona glomerulosa Endocrinology. 113: 1377-1386. PMID 6311519  1
1983 Farese RV, Sabir MA, Larson RE, Trudeau W. Further observations on the increases in inositide phospholipids after stimulation by ACTH, cAMP and insulin, and on discrepancies in phosphatidylinositol mass and 32PO4-labeling during inhibition of hormonal effects by cycloheximide Cell Calcium. 4: 195-218. PMID 6311422 DOI: 10.1016/0143-4160(83)90033-7  1
1983 Farese RV. The role of the phosphatidate-inositide cycle in the action of steroidogenic agents Journal of Steroid Biochemistry. 19: 1029-1032. PMID 6310253 DOI: 10.1016/0022-4731(83)90049-3  1
1983 Farese RV, Ling NC, Sabir MA, Larson RE, Trudeau WL. Comparison of effects of adrenocorticotropin and Lys-gamma 3-melanocyte-stimulating hormone on steroidogenesis, adenosine 3',5'-monophosphate production, and phospholipid metabolism in rat adrenal fasciculata-reticularis cells in vitro. Endocrinology. 112: 129-32. PMID 6291913 DOI: 10.1210/ENDO-112-1-129  0.01
1983 Farese RV. The phosphatidate-phosphoinositide cycle: An intracellular messenger system in the action of hormones and neurotransmitters Metabolism. 32: 628-641. PMID 6133206 DOI: 10.1016/0026-0495(83)90035-5  1
1983 Farese RV. Phosphoinositide metabolism and hormone action Endocrine Reviews. 4: 78-95. PMID 6131819  1
1982 Farese RV, Larson RE, Sabir MA. Ca2+-dependent and Ca2+-independent mechanisms for phosphatidylinositol hydrolysis and 32P-labeling during cholinergic stimulation of the rat submaxillary gland in vitro Archives of Biochemistry and Biophysics. 219: 204-208. PMID 6817715 DOI: 10.1016/0003-9861(82)90150-3  1
1982 Farese RV. The role of inositide phospholipids in the action of steroidogenic hormones Cell Calcium. 3: 441-450. PMID 6297742 DOI: 10.1016/0143-4160(82)90029-X  1
1982 Lowitt S, Farese RV, Sabir MA, Root AW. Rat Leydig cell phospholipid content is increased by luteinizing hormone and 8-bromo-cyclic AMP Endocrinology. 111: 1415-1417. PMID 6288363  1
1982 Farese RV, Sabir MA, Larson RE. Comparison of changes in inositide and noninositide phospholipids during acute and prolonged adrenocorticotropic hormone treatment in vivo Biochemistry. 21: 3318-3321. PMID 6288071  1
1982 Farese RV, Larson RE, Sabir MA. Insulin acutely increases phospholipids in the phosphatidate-inositide cycle in rat adipose tissue Journal of Biological Chemistry. 257: 4042-4045. PMID 6279623  1
1982 Farese RV, Larson RE, Sabir MA. Ca2+-Dependent and Ca2+-independent effects of pancreatic secretagogues on phosphatidylinositol metabolism Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 710: 391-399. PMID 6176275 DOI: 10.1016/0005-2760(82)90122-9  1
1982 Farese RV, Sabir MA, Larson RE. Insulin acutely increases phospholipids in the phosphatidate-polyphosphoinositide cycle in rat adipose tissue Federation Proceedings. 41.  1
1982 Davis JS, Farese RV, Clark MR. LH and GnRH acutely increase phosphatidylinositol levels in rat granulosa cells Biology of Reproduction. 26.  1
1981 Farese RV, Larson RE, Sabir MA, Gomez-Sanchez C. Effects of angiotensin-II and potassium on phospholipid metabolism in the adrenal zona glomerulosa Journal of Biological Chemistry. 256: 11093-11097. PMID 7287754  1
1981 Farese RV, Bidot-Lopez P, Sabir MA, Larson RE. The phosphatidate-polyphosphoinositide cycle: Activation by parathyroid hormone and dibutyryl-cAMP in rabbit kidney cortex Annals of the New York Academy of Sciences. 539-551. PMID 6280554  1
1981 Farese RV, Sabir MA, Larson RE. Adrenocorticotropin and adenosine 3',5'-monophosphate stimulate de novo synthesis of adrenal phosphatidic acid by a cycloheximide-sensitive, Ca++-dependent mechanism Endocrinology. 109: 1895-1901. PMID 6273120  1
1981 Farese RV, Sabir MA, Larson RE. Effects of adrenocorticotropin and cycloheximide on adrenal diglyceride kinase Biochemistry. 20: 6047-6051. PMID 6272834  1
1981 Farese RV, Sabir MA, Larson RE. Kinetic aspects of cycloheximide-induced reversal of adrenocorticotropin effects on steroidogenesis and phospholipid metabolism in rat adrenal sections in vitro Endocrinology. 109: 1424-1427. PMID 6271529  1
1981 Farese RV, Sabir MA, Larson RE. Effects of dibutyryl cyclic AMP and theophylline on rat pancreatic phospholipids in vitro Ca2+-sensitive decrease in phosphatidylinositol and cycloheximide-sensitive increase in phosphatidic acid Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 665: 463-470. PMID 6271229 DOI: 10.1016/0005-2760(81)90259-9  1
1981 Davis JS, Farese RV, Marsh JM. Stimulation of phospholipid labeling and steroidogenesis by luteinizing hormone in isolated bovine luteal cells Endocrinology. 109: 469-475. PMID 6265190  1
1981 Bidot-Lopez P, Farese RV, Sabir MA. Parathyroid hormone and adenosine-3',5'-monophosphate acutely increase phospholipids of the phosphatidate-polyphosphoinositide pathway in rabbit kidney cortex tubules in vitro by a cycloheximide-sensitive process Endocrinology. 108: 2078-2081. PMID 6262047  1
1981 Farese RV, Sabir MA, Larson RE. A23187 inhibits adrenal protein synthesis and the effects of adrenocorticotropin (ACTH) on steroidogenesis and phospholipid metabolism in rat adrenal cells in vitro: Further evidence implicating phospholipids in the steroidogenic action of ACTH Endocrinology. 108: 1243-1246. PMID 6258900  1
1981 Farese RV, Larson RE, Sabir MA. Insulin and its secretagogues activate Ca2+ -dependent phosphatidylinositol breakdown and amylase secretion in rat pancreas in vitro Diabetes. 30: 396-401. PMID 6164587  1
1980 Farese RV, Rodriguez-Colome M, O'Malley BC. Urinary prostaglandins following frusemide treatment and salt depletion in normal subjects and subjects with diabetic hyporeninaemic hypoaldosteronism Clinical Endocrinology. 13: 447-453. PMID 7014040  1
1980 Farese RV. How to make sense out of the new thyroid tests Medical Times. 108: 95-111. PMID 6767171  1
1980 Farese RV, Sabir MA, Larson RE. Kinetic aspects of cycloheximide-induced reversal of adrenocorticotropin effects on steroidogenesis and adrenal phospholipids in vivo Proceedings of the National Academy of Sciences of the United States of America. 77: 7189-7193. PMID 6261246  1
1980 Farese RV, Sabir MA, Larson RE. Potassium and angiotensin II increase the concentrations of phosphatidic acid, phosphatidylinositol, and polyphosphoinositides in rat adrenal capsules in vitro Journal of Clinical Investigation. 66: 1428-1431. PMID 6255013  1
1980 Farese RV, Bidot-López P, Sabir A, Smith JS, Schinbeckler B, Larson R. Parathyroid hormone acutely increases polyphosphoinositides of the rabbit kidney cortex by a cycloheximide-sensitive process. The Journal of Clinical Investigation. 65: 1523-6. PMID 6251113 DOI: 10.1172/JCI109818  1
1980 Farese RV, Sabir MA, Larson RE. On the mechanism whereby ACTH and cyclic AMP increase adrenal polyphosphoinositides. Rapid stimulation of the synthesis of phosphatidic acid and derivatives of CDP ~ diacylglycerol Journal of Biological Chemistry. 255: 7232-7237. PMID 6248553  1
1980 Farese RV, Sabir AM, Vandor SL, Larson RE. Are polyphosphoinositides the cycloheximide-sensitive mediator in the steroidogenic actions of adrenocorticotropin and adenosine-3',5'-monophosphate? Journal of Biological Chemistry. 255: 5728-5734. PMID 6247344  1
1980 Farese RV, Sabir AM. Polyphosphoinositides: Stimulator of mitochondrial cholesterol side chain cleavage and possible identification as an adrenocorticotropin-induced, cycloheximide-sensitive, cytosolic, steroidogenic factor Endocrinology. 106: 1869-1879. PMID 6245854  1
1980 Farese RV, Prudente WJ, Chuang LT. Non-esterified cholesterol-rich adrenal lipid fractions: Preparation, properties and preferential utilization for cholesterol side-chain cleavage by corticotropin-stimulated adrenal mitochondria Biochemical Journal. 186: 145-152. PMID 6245638  1
1980 Farese RV, Larson RE, Sabir MA. Effects of Ca2+ ionophore A23187 and Ca2+ deficiency on pancreatic phospholipids and amylase release in vitro Bba - General Subjects. 633: 479-484. PMID 6163455 DOI: 10.1016/0304-4165(80)90205-6  1
1980 Farese RV. In Reply Archives of Internal Medicine. 140: 583-584. DOI: 10.1001/archinte.1980.00330160143057  1
1980 Farese RV, Sabir MA, Larson RE. Effects of ACTH and cycloheximide on adrenal phosphatidic acid synthesis Clinical Research. 28.  1
1979 Farese RV, Karsh SJ, Bidot-López P. Acute intermittent porphyria associated with inappropriate antidiuretic hormone secretion, Hypokalemic alkalosis, and secondary hyperaldosteronism Southern Medical Journal. 72: 1201-1203. PMID 472850  1
1979 Farese RV. Hypothyroidism: Primary or secondary? Hospital Practice. 14: 153-159. PMID 428982  1
1979 Farese RV, Sabir AM. Polyphosphorylated glycerolipids mimic adrenocorticotropin-induced stimulation of mitochondrial pregnenolone synthesis Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 575: 299-304. PMID 228742 DOI: 10.1016/0005-2760(79)90032-8  1
1979 Farese RV, Sabir AM, Vandor SL. Adrenocorticotropin acutely increases adrenal polyphosphoinositides Journal of Biological Chemistry. 254: 6842-6844. PMID 222747  1
1979 Farese RV, Rodriguez ME, O'Malley BC, Jamieson E, Pollet RJ. Combined hypothalamic hypothyroidism and secondary adrenal insufficiency. Misdiagnosed as primary hypothyroidism. Archives of Internal Medicine. 139: 99-100. PMID 104680 DOI: 10.1001/archinte.139.1.99  1
1979 Farese RV, Rodriguez ME, O'malley BC, Jamieson E, Pollet RJ. Combined Hypothalamic Hypothyroidism and Secondary Adrenal Insufficiency: Misdiagnosed as Primary Hypothyroidism Archives of Internal Medicine. 139: 99-100. DOI: 10.1001/archinte.1979.03630380077025  1
1979 Farese RV, Sabir MA, Vandor SL, Larson RE. Polyphosphoinositides: The apparent mediator for effects of ACTH on adrenal steroidogenesis Clinical Research. 27.  1
1978 Farese RF, Prudente WJ. On the role of intra-adrenal unesterified cholesterol in the steroidegenic effect of corticotropin Bba - General Subjects. 544: 77-84. PMID 214150 DOI: 10.1016/0304-4165(78)90211-8  1
1978 Farese RV, Prudente WJ. On the role of calcium in adrenocorticotropin-induced changes in mitochondrial pregnenolone synthesis Endocrinology. 103: 1264-1271. PMID 33801  1
1978 Farese RV, Prudente WJ. Corticotropin-induced changes in a soluble desmolase preparation Bba - General Subjects. 539: 142-161. PMID 24476 DOI: 10.1016/0304-4165(78)90002-8  1
1978 Farese RV, Rodriquez ME. Urinary prostaglandin levels in diabetic hyporeninemic hypoaldosteronism Clinical Research. 26.  1
1978 Farese RV, Sabir MA, Chuang LT. Studies on the mechanism of ACTH action on steroidogenesis in cell-free systems Clinical Research. 26.  1
1977 Farese RV, Prudente WJ. Localization of the metabolic processes affected by calcium during corticotropin action Bba - General Subjects. 497: 386-395. PMID 192312 DOI: 10.1016/0304-4165(77)90196-9  1
1977 Farese RV, Prudente WJ. On the requirement for protein synthesis during corticotropin induced stimulation of cholesterol side chain cleavage in rat adrenal mitochondrial and solubilized desmolase preparations Biochimica Et Biophysica Acta. 496: 567-570. PMID 189847  1
1977 Farese RV, Prudente WJ. On the requirement for protein synthesis during corticotropin-induced stimulation of cholesterol side chain cleavage in rat adrenal mitochondrial and solubilized desmolase preparations Bba - General Subjects. 496: 563-565. DOI: 10.1016/0304-4165(77)90339-7  1
1971 Farese RV. On the requirement for calcium during the steroidogenic effect of ACTH Endocrinology. 89: 1057-1063. PMID 4398394  1
1971 Farese RV. Stimulation of pregnenolone synthesis by ACTH in rat adrenal sections Endocrinology. 89: 958-962. PMID 4328499  1
1971 Farese RV. Stimulatory effects of calcium on protein synthesis in adrenal (and thyroidal) cell-free systems as related to trophic hormone action Endocrinology. 89: 1064-1074. PMID 4328496  1
1971 Farese RV. Calcium as a mediator of adrenocorticotrophic hormone action on adrenal protein synthesis Science. 173: 447-450. PMID 4326721  1
1970 Farese RV. Inhibition of cholesterol side chain cleavage by cyanoketone (2α-cyano-4,4,17α-trimethyl-17β-hydroxyandrost-5-en-3-one) Steroids. 15: 245-250. PMID 5459077 DOI: 10.1016/S0039-128X(70)80037-X  1
1970 Linarelli LG, Farese RV. The effects of imidazole on adrenal metabolism in vitro Pharmacology. 4: 33-38. PMID 4393463  1
1969 Glinsmann WH, Hern EP, Linarelli LG, Farese RV. Similarities between effects of adenosine 3',5'-monophosphate and guanosine 3' 5'-monophosphate on liver and adrenal metabolism Endocrinology. 85: 711-719. PMID 4389873  1
1969 Farese RV. Effects of ACTH and cyclic-AMP in vitro on incorporation of 3H-leucine and 14C-orotic acid into protein and RNA in the presence of an inhibitor of cholesterol side chain cleavage Endocrinology. 85: 1209-1212. PMID 4310490  1
1969 Farese RV, Linarelli LG, Glinsmann WH, Ditzion BR, Paul MI, Pauk GA. Persistence of the steroidogenic effect of adenosin-3',5'-monophosphate in vitro: evidence for a third factor during the steroidogenic effect of ACTH. Endocrinology. 85: 867-74. PMID 4309501 DOI: 10.1210/ENDO-85-5-867  0.01
1967 Farese RV. Adrenocorticotrophin-induced changes in the steroidogenic activity of adrenal cell-free preparations Biochemistry. 6: 2052-2065. PMID 4383053  1
1967 Farese RV, Schnure JJ. Effects of ACTH on adrenal RNA synthesis Endocrinology. 80: 872-882. PMID 4290300  1
1966 Farese RV. Effects of actinomycin D on ACTH-induced corticosteroidogenesis Endocrinology. 78: 929-936. PMID 4379923  1
1966 Farese RV. Early effects of ACTH on adrenal protein synthesis Endocrinology. 78: 125-136. PMID 4286050  1
1965 FARESE RV. QUANTITATIVE COMPARISON OF THE EFFECTS OF ACTH ADMINISTRATION ON THE ACTIVITIES OF SOLUBLE CELL FRACTION AND MICROSOMES FOR INCORPORATION OF AMINO ACID INTO PROTEIN Endocrinology. 76: 795-797. PMID 14289207  1
1964 FARESE RV. CHANGES IN (14C)GLYCINE-INCORPORATING ACTIVITIES OF RAT-ADRENAL Biochimica Et Biophysica Acta. 91: 515-521. PMID 14254022  1
1964 FARESE RV. FURTHER STUDIES ON THE STIMULATION OF ADRENAL PROTEIN SYNTHESIS BY Endocrinology. 74: 579-585. PMID 14183203 DOI: 10.1210/ENDO-74-4-579  1
1964 Farese RV. Inhibition of the steroidogenic effect of ACTH and incorporation of amino acid into rat adrenal protein in vitro by chloramphenicol Bba Specialized Section On Nucleic Acids and Related Subjects. 87: 699-701.  1
1964 Farese RV. Changes in [14C]glycine-incorporating activities of rat-adrenal microsomes and soluble cell fraction during prolonged adrenocorticotropin administration Bba Specialized Section On Nucleic Acids and Related Subjects. 91: 515-521.  1
1963 Farese RV, Reddy WJ. Observations on the interrelations between adrenal protein, RNA and DNA during prolonged ACTH administration Bba - Biochimica Et Biophysica Acta. 76: 145-148. PMID 14071610  1
1963 FARESE RV, REDDY WJ. EFFECT OF ADRENOCORTICOTROPHIN ON ADRENAL PROTEIN SYNTHESIS Endocrinology. 73: 294-303. PMID 14065106  1
1962 FARESE RV, PLAGER JE. The in vitro red blood cell uptake of C-14-cortisol; studies of plasma protein binding of cortisol in normal and abnormal states The Journal of Clinical Investigation. 41: 53-60. PMID 13891604  1
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