Paloma H. Giangrande - Publications

Molecular & Cell Biology University of Iowa, Iowa City, IA 
Molecular Biology, Cell Biology, Oncology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Urak KT, Blanco GN, Shubham S, Lin LH, Dassie JP, Thiel WH, Chen Y, Sonkar VK, Lei B, Murthy S, Gutierrez WR, Wilson ME, Stiber JA, Klesney-Tait J, Dayal S, ... ... Giangrande PH, et al. RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome. Nature Communications. 10: 116. PMID 30631065 DOI: 10.1038/S41467-018-08030-Y  0.6
2016 Thiel WH, Esposito CL, Dickey DD, Dassie JP, Long ME, Adam J, Streeter J, Schickling B, Takapoo M, Flenker KS, Klesney-Tait J, Franciscis V, Miller FJ, Giangrande PH. Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 779-787. PMID 28135581 DOI: 10.1038/mt.2015.235  0.6
2016 Xu X, Dickey DD, Chen SJ, Giangrande PH. Structural Computational Modeling of RNA Aptamers. Methods (San Diego, Calif.). PMID 26972787 DOI: 10.1016/J.Ymeth.2016.03.004  0.6
2016 Urak KT, Shore S, Rockey WM, Chen SJ, McCaffrey AP, Giangrande PH. In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs. Methods (San Diego, Calif.). PMID 26972786 DOI: 10.1016/J.Ymeth.2016.03.003  0.6
2016 Thiel WH, Giangrande PH. AFBI assay - Aptamer Fluorescence Binding and Internalization assay for cultured adherent cells. Methods (San Diego, Calif.). PMID 26972784 DOI: 10.1016/J.Ymeth.2016.03.005  0.6
2016 Thiel WH, Esposito CL, Dickey DD, Dassie JP, Long ME, Adam J, Streeter J, Schickling B, Takapoo M, Flenker KS, Klesney-Tait J, de Franciscis V, Miller FJ, Giangrande PH. Smooth Muscle Cell-Targeted RNA Aptamer Inhibits Neointimal Formation. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26732878 DOI: 10.1038/Mt.2015.235  0.6
2016 Dickey DD, Thomas GS, Dassie JP, Giangrande PH. Method for Confirming Cytoplasmic Delivery of RNA Aptamers. Methods in Molecular Biology (Clifton, N.J.). 1364: 209-17. PMID 26472453 DOI: 10.1007/978-1-4939-3112-5_17  0.6
2015 Dickey DD, Giangrande PH. Oligonucleotide aptamers: A next-generation technology for the capture and detection of circulating tumor cells. Methods (San Diego, Calif.). PMID 26631715 DOI: 10.1016/J.Ymeth.2015.11.020  0.6
2015 Thiel WH, Giangrande PH. Analyzing HT-SELEX data with the Galaxy Project tools - A web based bioinformatics platform for biomedical research. Methods (San Diego, Calif.). PMID 26481156 DOI: 10.1016/J.Ymeth.2015.10.008  0.6
2015 Condorelli G, Giangrande PH, de Franciscis V. Arresting the colonial destiny of metastatic seeds with DNA aptamers. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 982-4. PMID 26022626 DOI: 10.1038/Mt.2015.85  0.6
2014 Dassie JP, Hernandez LI, Thomas GS, Long ME, Rockey WM, Howell CA, Chen Y, Hernandez FJ, Liu XY, Wilson ME, Allen LA, Vaena DA, Meyerholz DK, Giangrande PH. Targeted inhibition of prostate cancer metastases with an RNA aptamer to prostate-specific membrane antigen. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1910-22. PMID 24954476 DOI: 10.1038/Mt.2014.117  0.6
2014 Esposito CL, Cerchia L, Catuogno S, De Vita G, Dassie JP, Santamaria G, Swiderski P, Condorelli G, Giangrande PH, de Franciscis V. Multifunctional aptamer-miRNA conjugates for targeted cancer therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1151-63. PMID 24441398 DOI: 10.1038/Mt.2014.5  0.6
2013 Dassie JP, Giangrande PH. Current progress on aptamer-targeted oligonucleotide therapeutics. Therapeutic Delivery. 4: 1527-46. PMID 24304250 DOI: 10.4155/Tde.13.118  0.6
2013 Gourronc FA, Rockey WM, Thiel WH, Giangrande PH, Klingelhutz AJ. Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells. Virology. 446: 325-33. PMID 24074596 DOI: 10.1016/j.virol.2013.08.015  0.6
2013 Hernandez LI, Flenker KS, Hernandez FJ, Klingelhutz AJ, McNamara JO, Giangrande PH. Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers. Pharmaceuticals (Basel, Switzerland). 6: 295-319. PMID 23894227 DOI: 10.3390/Ph6030295  0.6
2012 Thiel WH, Bair T, Peek AS, Liu X, Dassie J, Stockdale KR, Behlke MA, Miller FJ, Giangrande PH. Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection. Plos One. 7: e43836. PMID 22962591 DOI: 10.1371/Journal.Pone.0043836  0.6
2012 Huang YZ, Hernandez FJ, Gu B, Stockdale KR, Nanapaneni K, Scheetz TE, Behlke MA, Peek AS, Bair T, Giangrande PH, McNamara JO. RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB. Molecular Pharmacology. 82: 623-35. PMID 22752556 DOI: 10.1124/Mol.112.078220  0.6
2012 Thiel KW, Hernandez LI, Dassie JP, Thiel WH, Liu X, Stockdale KR, Rothman AM, Hernandez FJ, McNamara JO, Giangrande PH. Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers. Nucleic Acids Research. 40: 6319-37. PMID 22467215 DOI: 10.1093/Nar/Gks294  0.6
2012 Berezhnoy A, Stewart CA, Mcnamara JO, Thiel W, Giangrande P, Trinchieri G, Gilboa E. Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1242-50. PMID 22434135 DOI: 10.1038/Mt.2012.18  0.6
2011 Rockey WM, Hernandez FJ, Huang SY, Cao S, Howell CA, Thomas GS, Liu XY, Lapteva N, Spencer DM, McNamara JO, Zou X, Chen SJ, Giangrande PH. Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling. Nucleic Acid Therapeutics. 21: 299-314. PMID 22004414 DOI: 10.1089/Nat.2011.0313  0.6
2011 Thiel WH, Bair T, Wyatt Thiel K, Dassie JP, Rockey WM, Howell CA, Liu XY, Dupuy AJ, Huang L, Owczarzy R, Behlke MA, McNamara JO, Giangrande PH. Nucleotide bias observed with a short SELEX RNA aptamer library. Nucleic Acid Therapeutics. 21: 253-63. PMID 21793789 DOI: 10.1089/Nat.2011.0288  0.6
2011 Rockey WM, Huang L, Kloepping KC, Baumhover NJ, Giangrande PH, Schultz MK. Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging. Bioorganic & Medicinal Chemistry. 19: 4080-90. PMID 21658962 DOI: 10.1016/J.Bmc.2011.05.010  0.6
2010 Thiel KW, Giangrande PH. Intracellular delivery of RNA-based therapeutics using aptamers. Therapeutic Delivery. 1: 849-61. PMID 21643487 DOI: 10.4155/Tde.10.61  0.6
2010 Pastor F, Kolonias D, Giangrande PH, Gilboa E. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay. Nature. 465: 227-30. PMID 20463739 DOI: 10.1038/Nature08999  0.6
2009 Dassie JP, Liu XY, Thomas GS, Whitaker RM, Thiel KW, Stockdale KR, Meyerholz DK, McCaffrey AP, McNamara JO, Giangrande PH. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nature Biotechnology. 27: 839-49. PMID 19701187 DOI: 10.1038/Nbt.1560  0.6
2009 Thiel KW, Giangrande PH. Therapeutic applications of DNA and RNA aptamers. Oligonucleotides. 19: 209-22. PMID 19653880 DOI: 10.1089/Oli.2009.0199  0.6
2009 Cerchia L, Giangrande PH, McNamara JO, de Franciscis V. Cell-specific aptamers for targeted therapies. Methods in Molecular Biology (Clifton, N.J.). 535: 59-78. PMID 19377980 DOI: 10.1007/978-1-59745-557-2_5  0.6
2008 Leung JY, Ehmann GL, Giangrande PH, Nevins JR. A role for Myc in facilitating transcription activation by E2F1. Oncogene. 27: 4172-9. PMID 18345030 DOI: 10.1038/Onc.2008.55  0.6
2008 McNamara JO, Kolonias D, Pastor F, Mittler RS, Chen L, Giangrande PH, Sullenger B, Gilboa E. Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice. The Journal of Clinical Investigation. 118: 376-86. PMID 18060045 DOI: 10.1172/Jci33365  0.6
2008 Mi J, Zhang X, Rabbani ZN, Liu Y, Reddy SK, Su Z, Salahuddin FK, Viles K, Giangrande PH, Dewhirst MW, Sullenger BA, Kontos CD, Clary BM. RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 66-73. PMID 17912235 DOI: 10.1038/Sj.Mt.6300320  0.6
2007 Giangrande PH, Zhang J, Tanner A, Eckhart AD, Rempel RE, Andrechek ER, Layzer JM, Keys JR, Hagen PO, Nevins JR, Koch WJ, Sullenger BA. Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 104: 12988-93. PMID 17652516 DOI: 10.1073/Pnas.0704754104  0.6
2006 McNamara JO, Andrechek ER, Wang Y, Viles KD, Rempel RE, Gilboa E, Sullenger BA, Giangrande PH. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nature Biotechnology. 24: 1005-15. PMID 16823371 DOI: 10.1016/J.Ymthe.2006.08.101  0.6
2005 Mi J, Zhang X, Giangrande PH, McNamara JO, Nimjee SM, Sarraf-Yazdi S, Sullenger BA, Clary BM. Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. Biochemical and Biophysical Research Communications. 338: 956-63. PMID 16256939 DOI: 10.1016/J.Bbrc.2005.10.043  0.6
2005 Zhu W, Giangrande PH, Nevins JR. Temporal control of cell cycle gene expression mediated by E2F transcription factors. Cell Cycle (Georgetown, Tex.). 4: 633-6. PMID 15876877 DOI: 10.4161/Cc.4.5.1650  0.6
2004 Giangrande PH, Zhu W, Schlisio S, Sun X, Mori S, Gaubatz S, Nevins JR. A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. Genes & Development. 18: 2941-51. PMID 15574595 DOI: 10.1101/Gad.1239304  0.6
2004 Zhu W, Giangrande PH, Nevins JR. E2Fs link the control of G1/S and G2/M transcription. The Embo Journal. 23: 4615-26. PMID 15510213 DOI: 10.1038/Sj.Emboj.7600459  0.6
2004 Giangrande PH, Zhu W, Rempel RE, Laakso N, Nevins JR. Combinatorial gene control involving E2F and E Box family members. The Embo Journal. 23: 1336-47. PMID 15014447 DOI: 10.1038/Sj.Emboj.7600134  0.6
2003 Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR. Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor. Molecular and Cellular Biology. 23: 3707-20. PMID 12748276 DOI: 10.1128/Mcb.23.11.3707-3720.2003  0.6
2001 Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 414: 457-62. PMID 11719808 DOI: 10.1038/35106593  0.6
2000 Giangrande PH, Kimbrel EA, Edwards DP, McDonnell DP. The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Molecular and Cellular Biology. 20: 3102-15. PMID 10757795 DOI: 10.1128/Mcb.20.9.3102-3115.2000  0.6
1999 Giangrande PH, Mcdonnell DP. The A and B isoforms of the human progesterone receptor: Two functionally different transcription factors encoded by a single gene Recent Progress in Hormone Research. 54: 291-314. PMID 10548881  0.6
1999 Tetel MJ, Giangrande PH, Leonhardt SA, McDonnell DP, Edwards DP. Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo. Molecular Endocrinology (Baltimore, Md.). 13: 910-24. PMID 10379890 DOI: 10.1210/Mend.13.6.0300  0.6
1997 Giangrande PH, Pollio G, McDonnell DP. Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor Journal of Biological Chemistry. 272: 32889-32900. PMID 9407067 DOI: 10.1074/Jbc.272.52.32889  0.6
1995 Stearns DM, Kennedy LJ, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Reduction of chromium(VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro. Biochemistry. 34: 910-9. PMID 7827049 DOI: 10.1021/Bi00003A025  0.6
1994 Stearns DM, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Chromium(VI) reduction by ascorbate: role of reactive intermediates in DNA damage in vitro. Environmental Health Perspectives. 102: 21-5. PMID 7843100 DOI: 10.1289/Ehp.94102S321  0.6
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