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Paloma H. Giangrande - Publications

Affiliations: 
Molecular & Cell Biology University of Iowa, Iowa City, IA 
Area:
Molecular Biology, Cell Biology, Oncology
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Year Citation  Score
2023 Lei B, Liu LB, Stokes L, Giangrande PH, Miller FJ, Yazdani SK. Smooth muscle cell-targeted RNA ligand promotes accelerated reendothelialization in a swine peripheral injury model. Molecular Therapy. Nucleic Acids. 34: 102023. PMID 37727270 DOI: 10.1016/j.omtn.2023.08.025  0.355
2023 Kolovskaya OS, Zyuzyukina AV, Dassie JP, Zamay GS, Zamay TN, Boyakova NV, Khorzhevskii VA, Kirichenko DA, Lapin IN, Shchugoreva IA, Artyushenko PV, Tomilin FN, Veprintsev DV, Glazyrin YE, Minic Z, ... ... Giangrande PH, et al. Monitoring of breast cancer progression via aptamer-based detection of circulating tumor cells in clinical blood samples. Frontiers in Molecular Biosciences. 10: 1184285. PMID 37363395 DOI: 10.3389/fmolb.2023.1184285  0.766
2023 Santana-Viera L, Dassie JP, Rosàs-Lapeña M, Garcia-Monclús S, Chicón-Bosch M, Pérez-Capó M, Pozo LD, Sanchez-Serra S, Almacellas-Rabaiget O, Maqueda-Marcos S, López-Alemany R, Thiel WH, Giangrande PH, Tirado OM. Combination of protein and cell internalization SELEX identifies a potential RNA therapeutic and delivery platform to treat EphA2-expressing tumors. Molecular Therapy. Nucleic Acids. 32: 758-772. PMID 37251690 DOI: 10.1016/j.omtn.2023.05.003  0.773
2023 Liu W, Iwamoto N, Marappan S, Luu K, Tripathi S, Purcell-Estabrook E, Shelke JD, Shah H, Lamattina A, Pan Q, Schrand B, Favaloro F, Bedekar M, Chatterjee A, Desai J, ... ... Giangrande PH, et al. Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference. Nucleic Acids Research. PMID 37070173 DOI: 10.1093/nar/gkad268  0.341
2022 Yazdani SK, Lei B, Cawthon CV, Cooper K, Huett C, Giangrande PH, Miller FJ. Local intraluminal delivery of a smooth muscle-targeted RNA ligand inhibits neointima growth in a porcine model of peripheral vascular disease. Molecular Therapy. Nucleic Acids. 29: 577-583. PMID 36090749 DOI: 10.1016/j.omtn.2022.08.007  0.334
2021 Shigdar S, Schrand B, Giangrande PH, de Franciscis V. Aptamers: cutting edge of cancer therapies. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34146729 DOI: 10.1016/j.ymthe.2021.06.010  0.373
2021 Catuogno S, Esposito CL, Giangrande PH. Stick-Based Methods for Aptamer-Mediated siRNA Targeted Delivery. Methods in Molecular Biology (Clifton, N.J.). 2282: 31-42. PMID 33928568 DOI: 10.1007/978-1-0716-1298-9_3  0.402
2020 Ptacek J, Zhang D, Qiu L, Kruspe S, Motlova L, Kolenko P, Novakova Z, Shubham S, Havlinova B, Baranova P, Chen SJ, Zou X, Giangrande P, Barinka C. Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer. Nucleic Acids Research. PMID 32525981 DOI: 10.1093/Nar/Gkaa494  0.45
2020 Almacellas-Rabaiget O, Monaco P, Huertas-Martinez J, García-Monclús S, Chicón-Bosch M, Maqueda-Marcos S, Fabra-Heredia I, Herrero-Martín D, Rello-Varona S, de Alava E, López-Alemany R, Giangrande PH, Tirado OM. LOXL2 Promotes Oncogenic Progression in Alveolar Rhabdomyosarcoma Independently of its Catalytic Activity. Cancer Letters. PMID 31911079 DOI: 10.1016/J.Canlet.2019.12.040  0.375
2019 Veeramani S, Blackwell SE, Thiel WH, Yang ZZ, Ansell SM, Giangrande PH, Weiner GJ. An RNA aptamer-based biomarker platform demonstrates high soluble CD25 occupancy by IL2 in the serum of follicular lymphoma patients. Cancer Immunology Research. PMID 31383650 DOI: 10.1158/2326-6066.Cir-18-0821  0.33
2019 Udofot O, Lin LH, Thiel WH, Erwin M, Turner E, Miller FJ, Giangrande PH, Yazdani SK. Delivery of Cell-Specific Aptamers to the Arterial Wall with an Occlusion Perfusion Catheter. Molecular Therapy. Nucleic Acids. 16: 360-366. PMID 30986697 DOI: 10.1016/J.Omtn.2019.03.005  0.516
2019 Urak KT, Blanco GN, Shubham S, Lin LH, Dassie JP, Thiel WH, Chen Y, Sonkar VK, Lei B, Murthy S, Gutierrez WR, Wilson ME, Stiber JA, Klesney-Tait J, Dayal S, ... ... Giangrande PH, et al. RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome. Nature Communications. 10: 116. PMID 30631065 DOI: 10.1038/S41467-018-08030-Y  0.752
2018 Ruiz Ciancio D, Vargas MR, Thiel WH, Bruno MA, Giangrande PH, Mestre MB. Aptamers as Diagnostic Tools in Cancer. Pharmaceuticals (Basel, Switzerland). 11. PMID 30208607 DOI: 10.3390/Ph11030086  0.446
2018 Garcia-Monclús S, López-Alemany R, Almacellas-Rabaiget O, Herrero-Martín D, Huertas-Martinez J, Lagares-Te L, Alba-Pavón P, Hontecillas-Prieto L, Mora J, de Álava E, Rello-Varona S, Giangrande PH, Tirado OM. EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma. International Journal of Cancer. PMID 29582409 DOI: 10.1002/Ijc.31405  0.379
2017 Kruspe S, Dickey DD, Urak KT, Blanco GN, Miller MJ, Clark KC, Burghardt E, Gutierrez WR, Phadke SD, Kamboj S, Ginader T, Smith BJ, Grimm SK, Schappet J, Ozer H, ... ... Giangrande PH, et al. Rapid and Sensitive Detection of Breast Cancer Cells in Patient Blood with Nuclease-Activated Probe Technology. Molecular Therapy. Nucleic Acids. 8: 542-557. PMID 28918054 DOI: 10.1016/J.Omtn.2017.08.004  0.439
2017 Kruspe S, Giangrande PH. Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects. Biomedicines. 5. PMID 28792479 DOI: 10.3390/Biomedicines5030045  0.523
2017 Kruspe S, Giangrande PH. Design and Preparation of Aptamer-siRNA Chimeras (AsiCs) for Targeted Cancer Therapy. Methods in Molecular Biology (Clifton, N.J.). 1632: 175-186. PMID 28730439 DOI: 10.1007/978-1-4939-7138-1_11  0.533
2017 Toulmé JJ, Giangrande PH, Mayer G, Suess B, Ducongé F, Sullenger B, de Franciscis V, Darfeuille F, Peyrin E. Aptamers in Bordeaux, 24-25 June 2016. Pharmaceuticals (Basel, Switzerland). 10. PMID 28117671 DOI: 10.3390/Ph10010014  0.374
2017 Giangrande P, Kruspe S, Dickey D, Kamboj S, Clark K, Urak K, Burghardt E, Smith B, Thomas A, McNamara J. Abstract P1-01-14: Nuclease-activated oligonucleotide probes for detection of breast cancer circulating tumor cells (CTCs): Early clinical results Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-01-14  0.396
2017 Veeramani S, Blackwell SE, Thiel WH, Giangrande PH, Weiner GJ. Abstract 1606: Targeting human T regulatory cells with novel Interleukin 2 alpha - IL2 complex-specific RNA aptamer Immunology. 77: 1606-1606. DOI: 10.1158/1538-7445.Am2017-1606  0.396
2016 Thiel WH, Esposito CL, Dickey DD, Dassie JP, Long ME, Adam J, Streeter J, Schickling B, Takapoo M, Flenker KS, Klesney-Tait J, Franciscis V, Miller FJ, Giangrande PH. Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 779-787. PMID 28135581 DOI: 10.1038/mt.2015.235  0.787
2016 Huertas-Martínez J, Court F, Rello-Varona S, Herrero-Martín D, Almacellas-Rabaiget O, Sáinz-Jaspeado M, Garcia-Monclús S, Lagares-Tena L, Buj R, Hontecillas-Prieto L, Sastre A, Azorin D, Sanjuan X, López-Alemany R, Moran S, ... ... Giangrande PH, et al. DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with Caveolin-1. Cancer Letters. PMID 27894957 DOI: 10.1016/J.Canlet.2016.11.020  0.309
2016 Iaboni M, Russo V, Fontanella R, Roscigno G, Fiore D, Donnarumma E, Esposito CL, Quintavalle C, Giangrande PH, de Franciscis V, Condorelli G. Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL. Molecular Therapy. Nucleic Acids. 5: e289. PMID 27111415 DOI: 10.1038/Mtna.2016.5  0.387
2016 Xu X, Dickey DD, Chen SJ, Giangrande PH. Structural Computational Modeling of RNA Aptamers. Methods (San Diego, Calif.). PMID 26972787 DOI: 10.1016/J.Ymeth.2016.03.004  0.457
2016 Urak KT, Shore S, Rockey WM, Chen SJ, McCaffrey AP, Giangrande PH. In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs. Methods (San Diego, Calif.). PMID 26972786 DOI: 10.1016/J.Ymeth.2016.03.003  0.472
2016 Thiel WH, Giangrande PH. AFBI assay - Aptamer Fluorescence Binding and Internalization assay for cultured adherent cells. Methods (San Diego, Calif.). PMID 26972784 DOI: 10.1016/J.Ymeth.2016.03.005  0.47
2016 Thiel WH, Esposito CL, Dickey DD, Dassie JP, Long ME, Adam J, Streeter J, Schickling B, Takapoo M, Flenker KS, Klesney-Tait J, de Franciscis V, Miller FJ, Giangrande PH. Smooth Muscle Cell-Targeted RNA Aptamer Inhibits Neointimal Formation. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26732878 DOI: 10.1038/Mt.2015.235  0.792
2016 Dickey DD, Thomas GS, Dassie JP, Giangrande PH. Method for Confirming Cytoplasmic Delivery of RNA Aptamers. Methods in Molecular Biology (Clifton, N.J.). 1364: 209-17. PMID 26472453 DOI: 10.1007/978-1-4939-3112-5_17  0.811
2016 Veeramani S, Blackwell SE, Thiel WH, Giangrande PH, Weiner GJ. Novel IL-2Ralpha (CD25)-Binding RNA Aptamer to Target T Regulatory Cells Blood. 128: 3697-3697. DOI: 10.1182/Blood.V128.22.3697.3697  0.464
2016 Dickey DD, Giangrande PH, Thiel WH. 744. Optimizing Conditions for Aptamer Folding Using a High-Throughput Aptamer Fluorescence Binding and Internalization (AFBI) Assay Molecular Therapy. 24: S293. DOI: 10.1016/S1525-0016(16)33552-3  0.398
2016 Dickey DD, Kruspe S, Urak KT, Thiel WH, Clark KC, Burghardt E, Dassie JP, Thomas A, McNamara JO, Giangrande PH. 263. Nuclease-Activated Oligonucleotide Probes for the Rapid and Robust Detection of Breast Cancer Circulating Tumor Cells (CTCs) Molecular Therapy. 24: S104. DOI: 10.1016/S1525-0016(16)33072-6  0.764
2015 Dickey DD, Giangrande PH. Oligonucleotide aptamers: A next-generation technology for the capture and detection of circulating tumor cells. Methods (San Diego, Calif.). PMID 26631715 DOI: 10.1016/J.Ymeth.2015.11.020  0.442
2015 Condorelli G, Giangrande PH, de Franciscis V. Arresting the colonial destiny of metastatic seeds with DNA aptamers. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 982-4. PMID 26022626 DOI: 10.1038/Mt.2015.85  0.44
2015 Thiel WH, Thiel KW, Flenker KS, Bair T, Dupuy AJ, McNamara JO, Miller FJ, Giangrande PH. Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cells. Methods in Molecular Biology (Clifton, N.J.). 1218: 187-99. PMID 25319652 DOI: 10.1007/978-1-4939-1538-5_11  0.55
2015 Veeramani S, Blackwell SE, Thiel WH, Giangrande PH, Weiner GJ. Abstract 5022: Generation of T regulatory-cell specific RNA aptamers Cancer Research. 75: 5022-5022. DOI: 10.1158/1538-7445.Am2015-5022  0.464
2015 Bair T, Miller RJ, Schappet J, Giangrande PH, Thiel WH. 67. AptmR: A High Throughput Rational Aptamer Truncation Algorithm Molecular Therapy. 23: S29. DOI: 10.1016/S1525-0016(16)33672-3  0.323
2015 Dickey DD, Thiel WH, Clard KC, Burghardt E, Dassie JP, McNamara II JO, Giangrande PH. 63. Rapid and Sensitive Detection of Circulating Tumor Cells with Nuclease-Activated Oligonucleotide Probes Molecular Therapy. 23: S28. DOI: 10.1016/S1525-0016(16)33668-1  0.764
2015 Thiel WH, Esposito CL, Dickey DD, Dassie JP, Long ME, Adam J, Streeter J, Schickling B, Takapoo M, Flenker KS, Klesney-Tait J, de Franciscis V, Miller FJ, Giangrande PH. 61. Vascular Smooth Muscle Cell RNA Aptamers for the Treatment of Cardiovascular Disease Molecular Therapy. 23: S27. DOI: 10.1016/S1525-0016(16)33666-8  0.778
2014 Dassie JP, Hernandez LI, Thomas GS, Long ME, Rockey WM, Howell CA, Chen Y, Hernandez FJ, Liu XY, Wilson ME, Allen LA, Vaena DA, Meyerholz DK, Giangrande PH. Targeted inhibition of prostate cancer metastases with an RNA aptamer to prostate-specific membrane antigen. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1910-22. PMID 24954476 DOI: 10.1038/Mt.2014.117  0.788
2014 Esposito CL, Cerchia L, Catuogno S, De Vita G, Dassie JP, Santamaria G, Swiderski P, Condorelli G, Giangrande PH, de Franciscis V. Multifunctional aptamer-miRNA conjugates for targeted cancer therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1151-63. PMID 24441398 DOI: 10.1038/Mt.2014.5  0.753
2013 Dassie JP, Giangrande PH. Current progress on aptamer-targeted oligonucleotide therapeutics. Therapeutic Delivery. 4: 1527-46. PMID 24304250 DOI: 10.4155/Tde.13.118  0.778
2013 Hernandez LI, Flenker KS, Hernandez FJ, Klingelhutz AJ, McNamara JO, Giangrande PH. Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers. Pharmaceuticals (Basel, Switzerland). 6: 295-319. PMID 23894227 DOI: 10.3390/Ph6030295  0.547
2012 Thiel WH, Bair T, Peek AS, Liu X, Dassie J, Stockdale KR, Behlke MA, Miller FJ, Giangrande PH. Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection. Plos One. 7: e43836. PMID 22962591 DOI: 10.1371/Journal.Pone.0043836  0.789
2012 Huang YZ, Hernandez FJ, Gu B, Stockdale KR, Nanapaneni K, Scheetz TE, Behlke MA, Peek AS, Bair T, Giangrande PH, McNamara JO. RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB. Molecular Pharmacology. 82: 623-35. PMID 22752556 DOI: 10.1124/Mol.112.078220  0.409
2012 Thiel KW, Hernandez LI, Dassie JP, Thiel WH, Liu X, Stockdale KR, Rothman AM, Hernandez FJ, McNamara JO, Giangrande PH. Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers. Nucleic Acids Research. 40: 6319-37. PMID 22467215 DOI: 10.1093/Nar/Gks294  0.808
2012 Berezhnoy A, Stewart CA, Mcnamara JO, Thiel W, Giangrande P, Trinchieri G, Gilboa E. Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1242-50. PMID 22434135 DOI: 10.1038/Mt.2012.18  0.313
2011 Rockey WM, Hernandez FJ, Huang SY, Cao S, Howell CA, Thomas GS, Liu XY, Lapteva N, Spencer DM, McNamara JO, Zou X, Chen SJ, Giangrande PH. Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling. Nucleic Acid Therapeutics. 21: 299-314. PMID 22004414 DOI: 10.1089/Nat.2011.0313  0.488
2011 Thiel WH, Bair T, Wyatt Thiel K, Dassie JP, Rockey WM, Howell CA, Liu XY, Dupuy AJ, Huang L, Owczarzy R, Behlke MA, McNamara JO, Giangrande PH. Nucleotide bias observed with a short SELEX RNA aptamer library. Nucleic Acid Therapeutics. 21: 253-63. PMID 21793789 DOI: 10.1089/Nat.2011.0288  0.771
2011 Rockey WM, Huang L, Kloepping KC, Baumhover NJ, Giangrande PH, Schultz MK. Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging. Bioorganic & Medicinal Chemistry. 19: 4080-90. PMID 21658962 DOI: 10.1016/J.Bmc.2011.05.010  0.462
2010 Thiel KW, Giangrande PH. Intracellular delivery of RNA-based therapeutics using aptamers. Therapeutic Delivery. 1: 849-61. PMID 21643487 DOI: 10.4155/Tde.10.61  0.508
2010 Pastor F, Kolonias D, Giangrande PH, Gilboa E. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay. Nature. 465: 227-30. PMID 20463739 DOI: 10.1038/Nature08999  0.377
2009 Dassie JP, Liu XY, Thomas GS, Whitaker RM, Thiel KW, Stockdale KR, Meyerholz DK, McCaffrey AP, McNamara JO, Giangrande PH. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nature Biotechnology. 27: 839-49. PMID 19701187 DOI: 10.1038/Nbt.1560  0.778
2009 Thiel KW, Giangrande PH. Therapeutic applications of DNA and RNA aptamers. Oligonucleotides. 19: 209-22. PMID 19653880 DOI: 10.1089/Oli.2009.0199  0.471
2009 Cerchia L, Giangrande PH, McNamara JO, de Franciscis V. Cell-specific aptamers for targeted therapies. Methods in Molecular Biology (Clifton, N.J.). 535: 59-78. PMID 19377980 DOI: 10.1007/978-1-59745-557-2_5  0.456
2008 Mi J, Zhang X, Rabbani ZN, Liu Y, Reddy SK, Su Z, Salahuddin FK, Viles K, Giangrande PH, Dewhirst MW, Sullenger BA, Kontos CD, Clary BM. RNA Aptamer-targeted Inhibition of NF-κB Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 66-73. PMID 28192708 DOI: 10.1038/sj.mt.6300320  0.301
2008 Leung JY, Ehmann GL, Giangrande PH, Nevins JR. A role for Myc in facilitating transcription activation by E2F1. Oncogene. 27: 4172-9. PMID 18345030 DOI: 10.1038/Onc.2008.55  0.306
2008 McNamara JO, Kolonias D, Pastor F, Mittler RS, Chen L, Giangrande PH, Sullenger B, Gilboa E. Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice. The Journal of Clinical Investigation. 118: 376-86. PMID 18060045 DOI: 10.1172/Jci33365  0.4
2008 Mi J, Zhang X, Rabbani ZN, Liu Y, Reddy SK, Su Z, Salahuddin FK, Viles K, Giangrande PH, Dewhirst MW, Sullenger BA, Kontos CD, Clary BM. RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 66-73. PMID 17912235 DOI: 10.1038/Sj.Mt.6300320  0.413
2007 Giangrande PH, Zhang J, Tanner A, Eckhart AD, Rempel RE, Andrechek ER, Layzer JM, Keys JR, Hagen PO, Nevins JR, Koch WJ, Sullenger BA. Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 104: 12988-93. PMID 17652516 DOI: 10.1073/Pnas.0704754104  0.425
2006 McNamara JO, Andrechek ER, Wang Y, Viles KD, Rempel RE, Gilboa E, Sullenger BA, Giangrande PH. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nature Biotechnology. 24: 1005-15. PMID 16823371 DOI: 10.1038/Nbt1223  0.573
2006 Catron DJ, Giangrande PH, Sullenger BA. 1028. Use of Antisense Oligonucleotides To Restore Activity in Mutant p53 Molecular Therapy. 13: S395. DOI: 10.1016/J.Ymthe.2006.08.1123  0.369
2006 Giangrande PH, McNamara JO, Andrecheck E, Gilboa E, Sullenger BA. 83. Cell_Type Specific Delivery of siRNAs with Aptamer_siRNA Chimeras Molecular Therapy. 13: S35. DOI: 10.1016/j.ymthe.2006.08.101  0.321
2005 Mi J, Zhang X, Giangrande PH, McNamara JO, Nimjee SM, Sarraf-Yazdi S, Sullenger BA, Clary BM. Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. Biochemical and Biophysical Research Communications. 338: 956-63. PMID 16256939 DOI: 10.1016/J.Bbrc.2005.10.043  0.465
2005 Zhu W, Giangrande PH, Nevins JR. Temporal control of cell cycle gene expression mediated by E2F transcription factors. Cell Cycle (Georgetown, Tex.). 4: 633-6. PMID 15876877 DOI: 10.4161/Cc.4.5.1650  0.316
2005 Giangrande PH, Zhang J, Layzer J, Hagen O, Nevins JR, Sullenger BA. 377. Developing siRNAs to the E2Fs to Control Vascular Growth and Remodeling Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.380  0.356
2004 Giangrande PH, Zhu W, Schlisio S, Sun X, Mori S, Gaubatz S, Nevins JR. A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. Genes & Development. 18: 2941-51. PMID 15574595 DOI: 10.1101/Gad.1239304  0.319
2003 Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR. Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor. Molecular and Cellular Biology. 23: 3707-20. PMID 12748276 DOI: 10.1128/Mcb.23.11.3707-3720.2003  0.304
2001 Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 414: 457-62. PMID 11719808 DOI: 10.1038/35106593  0.353
2000 Giangrande PH, Kimbrel EA, Edwards DP, McDonnell DP. The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Molecular and Cellular Biology. 20: 3102-15. PMID 10757795 DOI: 10.1128/Mcb.20.9.3102-3115.2000  0.313
1997 Giangrande PH, Pollio G, McDonnell DP. Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor Journal of Biological Chemistry. 272: 32889-32900. PMID 9407067 DOI: 10.1074/Jbc.272.52.32889  0.32
Low-probability matches (unlikely to be authored by this person)
2019 Cao J, An D, Galduroz M, Zhuo J, Liang S, Eybye M, Frassetto A, Kuroda E, Funahashi A, Santana J, Mihai C, Benenato KE, Kumarasinghe ES, Sabnis S, Salerno T, ... ... Giangrande PH, et al. mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31056400 DOI: 10.1016/J.Ymthe.2019.04.017  0.298
2001 Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, et al. Myc requires distinct E2F activities to induce S phase and apoptosis. Molecular Cell. 8: 105-13. PMID 11511364 DOI: 10.1016/S1097-2765(01)00275-1  0.297
1999 Wagner BL, Pollio G, Giangrande P, Webster JC, Breslin M, Mais DE, Cook CE, Vedeckis WV, Cidlowski JA, McDonnell DP. The novel progesterone receptor antagonists RTI 3021-012 and RTI 3021-022 exhibit complex glucocorticoid receptor antagonist activities: implications for the development of dissociated antiprogestins. Endocrinology. 140: 1449-58. PMID 10067874 DOI: 10.1210/Endo.140.3.6581  0.289
2023 Ruiz-Ciancio D, Lin LH, Veeramani S, Barros MN, Sanchez D, Di Bartolo AL, Masone D, Giangrande PH, Mestre MB, Thiel WH. Selection of a novel cell-internalizing RNA aptamer specific for CD22 antigen in B cell acute lymphoblastic leukemia. Molecular Therapy. Nucleic Acids. 33: 698-712. PMID 37662970 DOI: 10.1016/j.omtn.2023.07.028  0.284
2016 Bair T, Wertz JS, Miller RJ, Schappet J, Giangrande PH, Thiel WH. 148. AptaMetrics: A Web-Based Aptamer Bioinformatics Platform Molecular Therapy. 24: S59. DOI: 10.1016/S1525-0016(16)32957-4  0.279
2004 Giangrande PH, Zhu W, Rempel RE, Laakso N, Nevins JR. Combinatorial gene control involving E2F and E Box family members. The Embo Journal. 23: 1336-47. PMID 15014447 DOI: 10.1038/Sj.Emboj.7600134  0.266
2021 Ibba ML, Ciccone G, Esposito CL, Catuogno S, Giangrande PH. Advances in mRNA non-viral delivery approaches. Advanced Drug Delivery Reviews. 177: 113930. PMID 34403751 DOI: 10.1016/j.addr.2021.113930  0.26
2004 Zhu W, Giangrande PH, Nevins JR. E2Fs link the control of G1/S and G2/M transcription. The Embo Journal. 23: 4615-26. PMID 15510213 DOI: 10.1038/Sj.Emboj.7600459  0.258
2015 Thiel WH, Giangrande PH. Analyzing HT-SELEX data with the Galaxy Project tools - A web based bioinformatics platform for biomedical research. Methods (San Diego, Calif.). PMID 26481156 DOI: 10.1016/J.Ymeth.2015.10.008  0.253
1999 Tetel MJ, Giangrande PH, Leonhardt SA, McDonnell DP, Edwards DP. Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo. Molecular Endocrinology (Baltimore, Md.). 13: 910-24. PMID 10379890 DOI: 10.1210/Mend.13.6.0300  0.247
2010 Rockey W, Walsh S, Liu X, Sunderland J, Meyerholz D, Thedens D, McNamara J, Schultz M, Giangrande P. Development of an RNA-based SPECT/CT Imaging Agent for Prostate Cancer International Journal of Radiation Oncology*Biology*Physics. 78: S163. DOI: 10.1016/J.Ijrobp.2010.07.402  0.237
1994 Stearns DM, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Chromium(VI) reduction by ascorbate: role of reactive intermediates in DNA damage in vitro. Environmental Health Perspectives. 102: 21-5. PMID 7843100 DOI: 10.1289/Ehp.94102S321  0.215
1995 Stearns DM, Kennedy LJ, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Reduction of chromium(VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro. Biochemistry. 34: 910-9. PMID 7827049 DOI: 10.1021/Bi00003A025  0.214
2023 Zhao XJ, Mohsen AI, Mihalik S, Solo K, Basu S, Aliu E, Shi H, Kochersberger C, Karunanidhi A, Van't Land C, Coughlan KA, Siddiqui S, Rice LM, Hillier S, Guadagnin E, ... ... Giangrande PH, et al. Messenger RNA rescues medium-chain acyl-CoA dehydrogenase deficiency in fibroblasts from patients and a murine model. Human Molecular Genetics. PMID 37162351 DOI: 10.1093/hmg/ddad076  0.18
1993 Wetterhahn K, Stearns D, Giangrande P, Phieffer L, Courtney K. The role of ascorbate in metabolism and genotoxicity of chromium(VI). Journal of Inorganic Biochemistry. 51: 551. DOI: 10.1016/0162-0134(93)85577-U  0.171
2023 Lei B, Wang C, Snow K, Graton ME, Tighe RM, Fager AM, Hoffman MR, Giangrande PH, Miller FJ. Inhalation of an RNA aptamer that selectively binds extracellular histones protects from acute lung injury. Molecular Therapy. Nucleic Acids. 31: 662-673. PMID 36910716 DOI: 10.1016/j.omtn.2023.02.021  0.17
2013 Gourronc FA, Rockey WM, Thiel WH, Giangrande PH, Klingelhutz AJ. Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells. Virology. 446: 325-33. PMID 24074596 DOI: 10.1016/j.virol.2013.08.015  0.17
1999 Giangrande PH, Mcdonnell DP. The A and B isoforms of the human progesterone receptor: Two functionally different transcription factors encoded by a single gene Recent Progress in Hormone Research. 54: 291-314. PMID 10548881  0.156
2023 Cao J, Markel A, Hanahoe E, Ketova T, Mihai C, Zalinger Z, Marquardt D, Amato NJ, Cheng YM, Reid DW, Dousis A, Giangrande PH, Schultz JR, Martini PGV, Finn PF. Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells. Amino Acids. PMID 36944899 DOI: 10.1007/s00726-023-03263-8  0.15
2021 Cao J, Choi M, Guadagnin E, Soty M, Silva M, Verzieux V, Weisser E, Markel A, Zhuo J, Liang S, Yin L, Frassetto A, Graham AR, Burke K, Ketova T, ... ... Giangrande PH, et al. mRNA therapy restores euglycemia and prevents liver tumors in murine model of glycogen storage disease. Nature Communications. 12: 3090. PMID 34035281 DOI: 10.1038/s41467-021-23318-2  0.141
2022 Zhao XJ, Mohsen AW, Mihalik S, Solo K, Aliu E, Shi H, Basu S, Kochersperger C, Van't Land C, Karunanidhi A, Coughlan KA, Siddiqui S, Rice LM, Hillier S, Guadagnin E, ... Giangrande PH, et al. Synthetic mRNA rescues very long-chain acyl-CoA dehydrogenase deficiency in patient fibroblasts and a murine model. Molecular Genetics and Metabolism. 138: 106982. PMID 36580829 DOI: 10.1016/j.ymgme.2022.106982  0.129
2020 Wei G, Cao J, Huang P, An P, Badlani D, Vaid K, Zhao S, Q-H Wang D, Zhuo J, Yin L, Frassetto A, Markel A, Presnyak V, Gandham S, Hua S, ... ... Giangrande PH, et al. Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4 mouse model of PFIC3. Journal of Hepatology. PMID 33340584 DOI: 10.1016/j.jhep.2020.12.010  0.084
2023 Herzog RW, Giangrande PH. The Nobel Prize awarded to pioneers of mRNA vaccines. Molecular Therapy : the Journal of the American Society of Gene Therapy. 31: 3105-3106. PMID 37863063 DOI: 10.1016/j.ymthe.2023.10.006  0.033
2022 Bricker-Anthony C, Giangrande PH. On integrity. Molecular Therapy. Nucleic Acids. 30: 595. PMID 36514355 DOI: 10.1016/j.omtn.2022.11.011  0.01
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