Paul L. Sorgen - Publications

Affiliations: 
Biochemistry and Molecular Biology University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Biochemistry, General Biophysics, Molecular Biology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zheng L, Li H, Cannon A, Trease AJ, Spagnol G, Zheng H, Radio S, Patel K, Batra S, Sorgen PL. Phosphorylation of Cx43 residue Y313 by Src contributes to blocking the interaction with Drebrin and disassembling gap junctions. Journal of Molecular and Cellular Cardiology. PMID 30448479 DOI: 10.1016/j.yjmcc.2018.11.008  0.68
2018 Trease AJ, Li H, Spagnol G, Zheng L, Stauch KL, Sorgen PL. Regulation of Connexin32 by ephrin receptors and T-cell protein tyrosine phosphatase. The Journal of Biological Chemistry. PMID 30401746 DOI: 10.1074/jbc.RA118.003883  0.68
2018 Spagnol G, Trease AJ, Zheng L, Gutierrez M, Basu I, Sarmiento C, Moore G, Cervantes M, Sorgen PL. Connexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin. International Journal of Molecular Sciences. 19. PMID 29882937 DOI: 10.3390/ijms19061562  0.68
2018 Sorgen PL, Trease AJ, Spagnol G, Delmar M, Nielsen MS. Protein⁻Protein Interactions with Connexin 43: Regulation and Function. International Journal of Molecular Sciences. 19. PMID 29748463 DOI: 10.3390/ijms19051428  0.68
2017 Jacobsen NL, Pontifex TK, Li H, Solan JL, Lampe PD, Sorgen PL, Burt JM. Regulation of Cx37 channel and growth suppressive properties by phosphorylation. Journal of Cell Science. PMID 28818996 DOI: 10.1242/jcs.202572  0.52
2017 Trease AJ, Capuccino JMV, Contreras J, Harris AL, Sorgen PL. Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization. Journal of Molecular and Cellular Cardiology. PMID 28754342 DOI: 10.1016/j.yjmcc.2017.07.010  0.68
2017 Li H, Spagnol G, Pontifex TK, Burt JM, Sorgen PL. Chemical shift assignments of the connexin37 carboxyl terminal domain. Biomolecular Nmr Assignments. PMID 28251507 DOI: 10.1007/s12104-017-9735-x  0.52
2016 Mir RA, Lovelace J, Schafer NP, Simone PD, Kellezi A, Kolar C, Spagnol G, Sorgen PL, Band H, Band V, Borgstahl GEO. Biophysical characterization and modeling of human Ecdysoneless (ECD) protein supports a scaffolding function. Aims Biophysics. 3: 195-208. PMID 28492064 DOI: 10.3934/biophy.2016.1.195  0.52
2016 Ambrosi C, Ren C, Spagnol G, Cavin G, Cone A, Grintsevich EE, Sosinsky GE, Sorgen PL. Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1. Plos One. 11: e0157073. PMID 27280719 DOI: 10.1371/journal.pone.0157073  1
2016 Li H, Spagnol G, Zheng L, Stauch KL, Sorgen PL. Regulation of Connexin43 function and expression by Tyrosine kinase 2. The Journal of Biological Chemistry. PMID 27235399 DOI: 10.1074/jbc.M116.727008  0.52
2016 Bahl K, Xie S, Spagnol G, Sorgen PL, Naslavsky N, Caplan S. EHD3 is Required for Tubular Recycling Endosome Stabilization and an Asparagine-Glutamic Acid Residue Pair within its EH Domain Dictates its Selective Binding to NPF Peptides. The Journal of Biological Chemistry. PMID 27189942 DOI: 10.1074/jbc.M116.716407  1
2016 Spagnol G, Kieken F, Kopanic JL, Li H, Zach S, Stauch KL, Grosely R, Sorgen PL. Structural Studies of the Nedd4 WW Domains and their Selectivity for the Cx43 Carboxyl-terminus. The Journal of Biological Chemistry. PMID 26841867 DOI: 10.1074/jbc.M115.701417  1
2015 Spagnol G, Al-Mugotir M, Kopanic JL, Zach S, Li H, Trease AJ, Stauch KL, Grosely R, Cervantes M, Sorgen PL. Secondary structural analysis of the carboxyl-terminal domain from different connexin isoforms. Biopolymers. PMID 26542351 DOI: 10.1002/bip.22762  1
2015 Kopanic JL, Schlingmann B, Koval M, Lau AF, Sorgen PL, Su VF. Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75). The Biochemical Journal. 466: 571-85. PMID 25583071 DOI: 10.1042/BJ20141042  1
2014 Kopanic JL, Al-mugotir MH, Kieken F, Zach S, Trease AJ, Sorgen PL. Characterization of the connexin45 carboxyl-terminal domain structure and interactions with molecular partners. Biophysical Journal. 106: 2184-95. PMID 24853747 DOI: 10.1016/j.bpj.2014.03.045  1
2014 Li H, Spagnol G, Naslavsky N, Caplan S, Sorgen PL. TC-PTP directly interacts with connexin43 to regulate gap junction intercellular communication. Journal of Cell Science. 127: 3269-79. PMID 24849651 DOI: 10.1242/jcs.145193  1
2014 Spagnol G, Sorgen PL, Spray DC. Structural order in Pannexin 1 cytoplasmic domains. Channels (Austin, Tex.). 8: 157-66. PMID 24751934 DOI: 10.4161/chan.28854  1
2014 Spagnol G, Reiling C, Kieken F, Caplan S, Sorgen PL. Chemical shift assignments of the C-terminal Eps15 homology domain-3 EH domain. Biomolecular Nmr Assignments. 8: 263-7. PMID 23754701 DOI: 10.1007/s12104-013-9497-z  1
2013 Nelson TK, Sorgen PL, Burt JM. Carboxy terminus and pore-forming domain properties specific to Cx37 are necessary for Cx37-mediated suppression of insulinoma cell proliferation. American Journal of Physiology. Cell Physiology. 305: C1246-56. PMID 24133065 DOI: 10.1152/ajpcell.00159.2013  1
2013 Cai B, Giridharan SS, Zhang J, Saxena S, Bahl K, Schmidt JA, Sorgen PL, Guo W, Naslavsky N, Caplan S. Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes. The Journal of Biological Chemistry. 288: 30172-80. PMID 24019528 DOI: 10.1074/jbc.M113.488627  1
2013 Kopanic JL, Al-Mugotir M, Zach S, Das S, Grosely R, Sorgen PL. An Escherichia coli strain for expression of the connexin45 carboxyl terminus attached to the 4th transmembrane domain. Frontiers in Pharmacology. 4: 106. PMID 23986705 DOI: 10.3389/fphar.2013.00106  1
2013 Grosely R, Kopanic JL, Nabors S, Kieken F, Spagnol G, Al-Mugotir M, Zach S, Sorgen PL. Effects of phosphorylation on the structure and backbone dynamics of the intrinsically disordered connexin43 C-terminal domain. The Journal of Biological Chemistry. 288: 24857-70. PMID 23828237 DOI: 10.1074/jbc.M113.454389  1
2013 Grosely R, Sorgen PL. A history of gap junction structure: hexagonal arrays to atomic resolution. Cell Communication & Adhesion. 20: 11-20. PMID 23469928 DOI: 10.3109/15419061.2013.775256  1
2013 Kopanic JL, Sorgen PL. Chemical shift assignments of the connexin45 carboxyl terminal domain: monomer and dimer conformations. Biomolecular Nmr Assignments. 7: 293-7. PMID 23070843 DOI: 10.1007/s12104-012-9431-9  1
2013 Grosely R, Kieken F, Sorgen PL. ¹H, ¹³C, and ¹⁵N backbone resonance assignments of the connexin43 carboxyl terminal domain attached to the 4th transmembrane domain in detergent micelles. Biomolecular Nmr Assignments. 7: 299-303. PMID 23065337 DOI: 10.1007/s12104-012-9432-8  1
2012 Nielsen MS, Axelsen LN, Sorgen PL, Verma V, Delmar M, Holstein-Rathlou NH. Gap junctions. Comprehensive Physiology. 2: 1981-2035. PMID 23723031 DOI: 10.1002/cphy.c110051  1
2012 Dolmatova E, Spagnol G, Boassa D, Baum JR, Keith K, Ambrosi C, Kontaridis MI, Sorgen PL, Sosinsky GE, Duffy HS. Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation. American Journal of Physiology. Heart and Circulatory Physiology. 303: H1208-18. PMID 22982782 DOI: 10.1152/ajpheart.00251.2012  1
2012 Manickam DS, Brynskikh AM, Kopanic JL, Sorgen PL, Klyachko NL, Batrakova EV, Bronich TK, Kabanov AV. Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury. Journal of Controlled Release : Official Journal of the Controlled Release Society. 162: 636-45. PMID 22902590 DOI: 10.1016/j.jconrel.2012.07.044  1
2012 Zhang J, Reiling C, Reinecke JB, Prislan I, Marky LA, Sorgen PL, Naslavsky N, Caplan S. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function. Traffic (Copenhagen, Denmark). 13: 745-57. PMID 22284051 DOI: 10.1111/j.1600-0854.2012.01334.x  1
2011 Locke D, Kieken F, Tao L, Sorgen PL, Harris AL. Mechanism for modulation of gating of connexin26-containing channels by taurine. The Journal of General Physiology. 138: 321-39. PMID 21844220 DOI: 10.1085/jgp.201110634  1
2010 Grosely R, Kieken F, Sorgen PL. Optimizing the solution conditions to solve the structure of the Connexin43 carboxyl terminus attached to the 4(th) transmembrane domain in detergent micelles. Cell Communication & Adhesion. 17: 23-33. PMID 20513204 DOI: 10.3109/15419061.2010.487956  1
2010 Kieken F, Spagnol G, Su V, Lau AF, Sorgen PL. NMR structure note: UBA domain of CIP75. Journal of Biomolecular Nmr. 46: 245-50. PMID 20127391 DOI: 10.1007/s10858-010-9397-9  1
2010 Kieken F, Sharma M, Jovic M, Giridharan SS, Naslavsky N, Caplan S, Sorgen PL. Mechanism for the selective interaction of C-terminal Eps15 homology domain proteins with specific Asn-Pro-Phe-containing partners. The Journal of Biological Chemistry. 285: 8687-94. PMID 20106972 DOI: 10.1074/jbc.M109.045666  1
2009 Bouvier D, Spagnol G, Chenavas S, Kieken F, Vitrac H, Brownell S, Kellezi A, Forge V, Sorgen PL. Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains. The Journal of Biological Chemistry. 284: 34257-71. PMID 19808665 DOI: 10.1074/jbc.M109.039594  1
2009 Kieken F, Jović M, Tonelli M, Naslavsky N, Caplan S, Sorgen PL. Structural insight into the interaction of proteins containing NPF, DPF, and GPF motifs with the C-terminal EH-domain of EHD1. Protein Science : a Publication of the Protein Society. 18: 2471-9. PMID 19798736 DOI: 10.1002/pro.258  1
2009 Verma V, Larsen BD, Coombs W, Lin X, Spagnol G, Sorgen PL, Taffet SM, Delmar M. Novel pharmacophores of connexin43 based on the "RXP" series of Cx43-binding peptides. Circulation Research. 105: 176-84. PMID 19556520 DOI: 10.1161/CIRCRESAHA.109.200576  1
2009 Jović M, Kieken F, Naslavsky N, Sorgen PL, Caplan S. Eps15 homology domain 1-associated tubules contain phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate and are required for efficient recycling. Molecular Biology of the Cell. 20: 2731-43. PMID 19369419 DOI: 10.1091/mbc.E08-11-1102  1
2009 Kieken F, Mutsaers N, Dolmatova E, Virgil K, Wit AL, Kellezi A, Hirst-Jensen BJ, Duffy HS, Sorgen PL. Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarction. Circulation Research. 104: 1103-12. PMID 19342602 DOI: 10.1161/CIRCRESAHA.108.190454  1
2009 Lewandowski R, Shibayama J, Oxford EM, Joshi-Mukherjee R, Coombs W, Sorgen PL, Taffet SM, Delmar M. Chemical gating of connexin channels Connexins: a Guide. 129-142. DOI: 10.1007/978-1-59745-489-6_5  1
2008 Bouvier D, Kieken F, Kellezi A, Sorgen PL. Structural changes in the carboxyl terminus of the gap junction protein connexin 40 caused by the interaction with c-Src and zonula occludens-1. Cell Communication & Adhesion. 15: 107-18. PMID 18649183 DOI: 10.1080/15419060802014347  1
2008 Kellezi A, Grosely R, Kieken F, Borgstahl GE, Sorgen PL. Purification and reconstitution of the connexin43 carboxyl terminus attached to the 4th transmembrane domain in detergent micelles. Protein Expression and Purification. 59: 215-22. PMID 18411056 DOI: 10.1016/j.pep.2008.01.023  1
2007 Bouvier D, Kieken F, Sorgen PL. (1)H, (13)C, and (15)N backbone resonance assignments of the carboxyl terminal domain of Connexin40. Biomolecular Nmr Assignments. 1: 155-7. PMID 19636853 DOI: 10.1007/s12104-007-9044-x  1
2007 Solan JL, Marquez-Rosado L, Sorgen PL, Thornton PJ, Gafken PR, Lampe PD. Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC. The Journal of Cell Biology. 179: 1301-9. PMID 18086922 DOI: 10.1083/jcb.200707060  1
2007 Kieken F, Jović M, Naslavsky N, Caplan S, Sorgen PL. EH domain of EHD1. Journal of Biomolecular Nmr. 39: 323-9. PMID 17899392 DOI: 10.1007/s10858-007-9196-0  1
2007 Naslavsky N, Rahajeng J, Chenavas S, Sorgen PL, Caplan S. EHD1 and Eps15 interact with phosphatidylinositols via their Eps15 homology domains. The Journal of Biological Chemistry. 282: 16612-22. PMID 17412695 DOI: 10.1074/jbc.M609493200  1
2007 Duffy HS, Iacobas I, Hotchkiss K, Hirst-Jensen BJ, Bosco A, Dandachi N, Dermietzel R, Sorgen PL, Spray DC. The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1. The Journal of Biological Chemistry. 282: 9789-96. PMID 17284442 DOI: 10.1074/jbc.M605261200  1
2007 Hirst-Jensen BJ, Sahoo P, Kieken F, Delmar M, Sorgen PL. Characterization of the pH-dependent interaction between the gap junction protein connexin43 carboxyl terminus and cytoplasmic loop domains. The Journal of Biological Chemistry. 282: 5801-13. PMID 17178730 DOI: 10.1074/jbc.M605233200  1
2006 Shibayama J, Gutiérrez C, González D, Kieken F, Seki A, Carrión JR, Sorgen PL, Taffet SM, Barrio LC, Delmar M. Effect of charge substitutions at residue his-142 on voltage gating of connexin43 channels. Biophysical Journal. 91: 4054-63. PMID 16963503 DOI: 10.1529/biophysj.106.085787  1
2006 Shibayama J, Lewandowski R, Kieken F, Coombs W, Shah S, Sorgen PL, Taffet SM, Delmar M. Identification of a novel peptide that interferes with the chemical regulation of connexin43. Circulation Research. 98: 1365-72. PMID 16690883 DOI: 10.1161/01.RES.0000225911.24228.9c  1
2005 Sorgen PL. How to solve a protein structure by nuclear magnetic resonance - The Connexin43 carboxyl terminal domain Practical Methods in Cardiovascular Research. 948-958. DOI: 10.1007/3-540-26574-0_48  1
2004 Sorgen PL, Duffy HS, Sahoo P, Coombs W, Delmar M, Spray DC. Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1. The Journal of Biological Chemistry. 279: 54695-701. PMID 15492000 DOI: 10.1074/jbc.M409552200  1
2004 Sorgen PL, Duffy HS, Spray DC, Delmar M. pH-dependent dimerization of the carboxyl terminal domain of Cx43. Biophysical Journal. 87: 574-81. PMID 15240490 DOI: 10.1529/biophysj.103.039230  1
2004 Krueger-Koplin RD, Sorgen PL, Krueger-Koplin ST, Rivera-Torres IO, Cahill SM, Hicks DB, Grinius L, Krulwich TA, Girvin ME. An evaluation of detergents for NMR structural studies of membrane proteins. Journal of Biomolecular Nmr. 28: 43-57. PMID 14739638 DOI: 10.1023/B:JNMR.0000012875.80898.8f  1
2004 Delmar M, Duffy HS, Sorgen PL, Taffet SM, Spray DC. Molecular Organization and Regulation of the Cardiac Gap Junction Channel Connexin43 Cardiac Electrophysiology: Fourth Edition. 66-76. DOI: 10.1016/B0-7216-0323-8/50011-7  1
2002 Sorgen PL, Hu Y, Guan L, Kaback HR, Girvin ME. An approach to membrane protein structure without crystals. Proceedings of the National Academy of Sciences of the United States of America. 99: 14037-40. PMID 12391320 DOI: 10.1073/pnas.182552199  1
2002 Sorgen PL, Duffy HS, Cahill SM, Coombs W, Spray DC, Delmar M, Girvin ME. Sequence-specific resonance assignment of the carboxyl terminal domain of Connexin43. Journal of Biomolecular Nmr. 23: 245-6. PMID 12238598 DOI: 10.1023/A:1019892719979  1
2002 Duffy HS, Sorgen PL, Girvin ME, O'Donnell P, Coombs W, Taffet SM, Delmar M, Spray DC. pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains. The Journal of Biological Chemistry. 277: 36706-14. PMID 12151412 DOI: 10.1074/jbc.M207016200  1
2002 Sorgen PL, Cahill SM, Krueger-Koplin RD, Krueger-Koplin ST, Schenck CC, Girvin ME. Structure of the Rhodobacter sphaeroides light-harvesting 1 beta subunit in detergent micelles. Biochemistry. 41: 31-41. PMID 11772000 DOI: 10.1021/bi011576j  1
1999 Sorgen PL, Bubb MR, Cain BD. Lengthening the second stalk of F1F0 ATP synthase in Escherichia coli Journal of Biological Chemistry. 274: 36261-36266. PMID 10593914 DOI: 10.1074/jbc.274.51.36261  1
1998 Sorgen PL, Caviston TL, Perry RC, Cain BD. Deletions in the second stalk of F1F0-ATP synthase in Escherichia coli Journal of Biological Chemistry. 273: 27873-27878. PMID 9774398 DOI: 10.1074/jbc.273.43.27873  1
1998 Caviston TL, Ketchum CJ, Sorgen PL, Nakamoto RK, Cain BD. Identification of an uncoupling mutation affecting the b subunit of F1F0 ATP synthase in Escherichia coli Febs Letters. 429: 201-206. PMID 9650590 DOI: 10.1016/S0014-5793(98)00597-3  1
1998 Sorgen PL, Bubb MR, McCormick KA, Edison AS, Cain BD. Formation of the b subunit dimer is necessary for interaction with F1- ATPase Biochemistry. 37: 923-932. PMID 9454582 DOI: 10.1021/bi972309+  1
1997 Sorgen PL, McCormick KA, Cain BD. Substitutions of ALA-79 Affect dimerization of the b subunit in F1F0 ATP synthase from escherichia coli Faseb Journal. 11.  1
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