Christina Chan - Publications

Affiliations: 
Cell and Molecular Biology Michigan State University, East Lansing, MI 
Area:
Molecular Biology, Bioinformatics Biology, System Science Engineering

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Angart PA, Adu-Berchie K, Carlson RJ, Vocelle DB, Chan C, Walton SP. Relative Quantification of siRNA Strand Loading into Ago2 for Design of Highly Active siRNAs. Methods in Molecular Biology (Clifton, N.J.). 1974: 41-56. PMID 31098994 DOI: 10.1007/978-1-4939-9220-1_4  0.72
2019 Chan C, Guo N, Duan X, Han W, Xue L, Bryan D, Wightman SC, Khodarev NN, Weichselbaum RR, Lin W. Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer. Biomaterials. PMID 31060867 DOI: 10.1016/j.biomaterials.2019.04.028  0.44
2019 Duan X, Chan C, Han W, Guo N, Weichselbaum RR, Lin W. Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors. Nature Communications. 10: 1899. PMID 31015397 DOI: 10.1038/s41467-019-09221-x  0.44
2019 Cho H, Stanzione F, Oak A, Kim GH, Yerneni S, Qi L, Sum AK, Chan C. Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation. Cell Reports. 27: 307-320.e5. PMID 30943411 DOI: 10.1016/j.celrep.2019.03.017  0.72
2019 Thompson R, Casali C, Chan C. Forskolin and IBMX Induce Neural Transdifferentiation of MSCs Through Downregulation of the NRSF. Scientific Reports. 9: 2969. PMID 30814572 DOI: 10.1038/s41598-019-39544-0  0.52
2018 Lu K, He C, Guo N, Chan C, Ni K, Lan G, Tang H, Pelizzari C, Fu YX, Spiotto MT, Weichselbaum RR, Lin W. Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy. Nature Biomedical Engineering. 2: 600-610. PMID 31015630 DOI: 10.1038/s41551-018-0203-4  0.44
2018 Liu C, Kray J, Chan C. Schwann Cells Enhance Penetration of Regenerated Axons into Three-Dimensional Microchannels. Tissue Engineering and Regenerative Medicine. 15: 351-361. PMID 30603560 DOI: 10.1007/s13770-018-0115-0  1
2018 Thompson R, Chan C. NRSF and Its Epigenetic Effectors: New Treatments for Neurological Disease. Brain Sciences. 8. PMID 30572571 DOI: 10.3390/brainsci8120226  0.52
2018 Lee EY, Cui K, Trope GE, Buys YM, Chan CH, Thavorn K, Jin YP. Eye care utilisation in Newfoundland and Labrador: access barriers and vision health outcomes. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 53: 342-348. PMID 30119787 DOI: 10.1016/j.jcjo.2017.11.012  0.36
2018 Duan X, Chan C, Lin W. Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy. Angewandte Chemie (International Ed. in English). PMID 30016571 DOI: 10.1002/anie.201804882  0.44
2018 Ni K, Lan G, Chan C, Quigley B, Lu K, Aung T, Guo N, La Riviere P, Weichselbaum RR, Lin W. Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy. Nature Communications. 9: 2351. PMID 29907739 DOI: 10.1038/s41467-018-04703-w  0.44
2017 Lan G, Ni K, Xu R, Lu K, Lin Z, Chan C, Lin W. Nanoscale Metal-Organic Layers for Deeply Penetrating X-ray Induced Photodynamic Therapy. Angewandte Chemie (International Ed. in English). PMID 28804945 DOI: 10.1002/anie.201704828  0.44
2016 Duan X, Chan C, Guo N, Han W, Weichselbaum RR, Lin W. Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer. Journal of the American Chemical Society. PMID 27976881 DOI: 10.1021/jacs.6b09538  0.44
2016 Thompson R, Chan C. Signal transduction of the physical environment in the neural differentiation of stem cells. Technology. 4: 1-8. PMID 27785459 DOI: 10.1142/S2339547816400070  0.52
2016 Vocelle D, Chesniak OM, Malefyt AP, Comiskey G, Adu-Berchie K, Smith MR, Chan C, Walton SP. Dextran functionalization enhances nanoparticle-mediated siRNA delivery and silencing. Technology. 4. PMID 27774502 DOI: 10.1142/S2339547816400100  0.72
2016 Poon C, Duan X, Chan C, Han W, Lin W. Nanoscale coordination polymers co-deliver carboplatin and gemcitabine for highly effective treatment of platinum-resistant ovarian cancer. Molecular Pharmaceutics. PMID 27712076 DOI: 10.1021/acs.molpharmaceut.6b00466  0.44
2016 Dong B, Chen S, Zhou F, Chan CH, Yi J, Zhang HF, Sun C. Real-time Functional Analysis of Inertial Microfluidic Devices via Spectral Domain Optical Coherence Tomography. Scientific Reports. 6: 33250. PMID 27619202 DOI: 10.1038/srep33250  0.4
2016 Liu C, Chan C. An Approach to Enhance Alignment and Myelination of Dorsal Root Ganglion Neurons. Journal of Visualized Experiments : Jove. PMID 27585118 DOI: 10.3791/54085  1
2016 Lu K, He C, Guo N, Chan C, Ni K, Weichselbaum RR, Lin W. A Chlorin-based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy. Journal of the American Chemical Society. PMID 27575718 DOI: 10.1021/jacs.6b06663  0.44
2016 Bilgin B, Nath A, Chan C, Walton SP. Characterization of transcription factor response kinetics in parallel. Bmc Biotechnology. 16: 62. PMID 27557669 DOI: 10.1186/s12896-016-0293-6  0.72
2016 He C, Duan X, Guo N, Chan C, Poon C, Weichselbaum RR, Lin W. Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy. Nature Communications. 7: 12499. PMID 27530650 DOI: 10.1038/ncomms12499  0.44
2016 Wang T, Srivastava S, Hartman M, Buhari SA, Chan CW, Iau P, Khin LW, Wong A, Tan SH, Goh BC, Lee SC. High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer. Oncotarget. PMID 27487140 DOI: 10.18632/oncotarget.10894  1
2016 Liu C, Kray J, Toomajian V, Chan C. Schwann Cell Migration on Patterned PDMS Microgrooved Surface. Tissue Engineering. Part C, Methods. PMID 27216726 DOI: 10.1089/ten.TEC.2015.0539  1
2016 He C, Poon C, Chan C, Yamada SD, Lin W. Nanoscale Coordination Polymers Co-deliver Chemotherapeutics and siRNAs to Eradicate Tumors of Cisplatin-Resistant Ovarian Cancer. Journal of the American Chemical Society. PMID 27088560 DOI: 10.1021/jacs.6b02486  0.44
2016 Stapleton JA, Kim J, Hamilton JP, Wu M, Irber LC, Maddamsetti R, Briney B, Newton L, Burton DR, Brown CT, Chan C, Buell CR, Whitehead TA. Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing. Plos One. 11: e0147229. PMID 26789840 DOI: 10.1371/journal.pone.0147229  0.72
2016 Nath A, Chan C. Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers. Scientific Reports. 6: 18669. PMID 26725848 DOI: 10.1038/srep18669  0.68
2015 Liu C, Pyne R, Kim J, Wright NT, Baek S, Chan C. The impact of pre-stretch induced surface anisotropy on axon regeneration. Tissue Engineering. Part C, Methods. PMID 26563431 DOI: 10.1089/ten.TEC.2015.0328  1
2015 Nath A, Li I, Roberts LR, Chan C. Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma. Scientific Reports. 5: 14752. PMID 26424075 DOI: 10.1038/srep14752  1
2015 Zhang L, Bell BA, Yu M, Chan CC, Peachey NS, Fung J, Zhang X, Caspi RR, Lin F. Complement anaphylatoxin receptors C3aR and C5aR are required in the pathogenesis of experimental autoimmune uveitis. Journal of Leukocyte Biology. PMID 26394814 DOI: 10.1189/jlb.3A0415-157R  0.44
2015 Vocelle D, Chan C, Walton SP. How can novel microscopic approaches shed light on the function of nucleic acid-based drugs? Future Medicinal Chemistry. 7: 1623-5. PMID 26381477 DOI: 10.4155/fmc.15.110  0.72
2015 Kowalsky CA, Faber MS, Nath A, Dann HE, Kelly VW, Liu L, Shanker P, Wagner EK, Maynard JA, Chan C, Whitehead TA. Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing. The Journal of Biological Chemistry. PMID 26296891 DOI: 10.1074/jbc.M115.676635  0.68
2015 Chan CK, Tüysüz H, Braun A, Ranjan C, La Mantia F, Miller BK, Zhang L, Crozier PA, Haber JA, Gregoire JM, Park HS, Batchellor AS, Trotochaud L, Boettcher SW. Advanced and In Situ Analytical Methods for Solar Fuel Materials. Topics in Current Chemistry. PMID 26267386 DOI: 10.1007/128_2015_650  1
2015 He C, Chan C, Weichselbaum RR, Fleming GF, Yamada SD, Lin W. Nanomedicine for Combination Therapy of Cancer. Ebiomedicine. 2: 366-7. PMID 26137577 DOI: 10.1016/j.ebiom.2015.05.013  0.44
2015 Duan X, Liu D, Chan C, Lin W. Polymeric Micelle-Mediated Delivery of DNA-Targeting Organometallic Complexes for Resistant Ovarian Cancer Treatment. Small (Weinheim An Der Bergstrasse, Germany). PMID 25963931 DOI: 10.1002/smll.201500288  0.44
2015 Lynam DA, Shahriari D, Wolf KJ, Angart PA, Koffler J, Tuszynski MH, Chan C, Walton P, Sakamoto J. Brain derived neurotrophic factor release from layer-by-layer coated agarose nerve guidance scaffolds. Acta Biomaterialia. 18: 128-31. PMID 25712385 DOI: 10.1016/j.actbio.2015.02.014  1
2015 Zhao H, Chiaro CR, Zhang L, Smith PB, Chan CY, Pedley AM, Pugh RJ, French JB, Patterson AD, Benkovic SJ. Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis. The Journal of Biological Chemistry. 290: 6705-13. PMID 25605736 DOI: 10.1074/jbc.M114.628701  1
2014 Chan CH, Trope GE, Badley EM, Buys YM, Jin YP. The impact of lack of government-insured routine eye examinations on the incidence of self-reported glaucoma, cataracts, and vision loss. Investigative Ophthalmology & Visual Science. 55: 8544-9. PMID 25491296 DOI: 10.1167/iovs.14-15361  0.36
2014 Zhang L, Liu L, Thompson R, Chan C. CREB modulates calcium signaling in cAMP-induced bone marrow stromal cells (BMSCs). Cell Calcium. 56: 257-68. PMID 25154887 DOI: 10.1016/j.ceca.2014.07.013  1
2014 Fang L, Cho HJ, Chan C, Feig M. Binding site multiplicity with fatty acid ligands: implications for the regulation of PKR kinase autophosphorylation with palmitate. Proteins. 82: 2429-42. PMID 24862841 DOI: 10.1002/prot.24607  1
2014 Huang C, Wu M, Du J, Liu D, Chan C. Systematic modeling for the insulin signaling network mediated by IRS(1) and IRS(2). Journal of Theoretical Biology. 355: 40-52. PMID 24703981 DOI: 10.1016/j.jtbi.2014.03.030  1
2014 Liu L, Chan C. The role of inflammasome in Alzheimer's disease. Ageing Research Reviews. 15: 6-15. PMID 24561250 DOI: 10.1016/j.arr.2013.12.007  0.56
2014 Lynam D, Peterson C, Maloney R, Shahriari D, Garrison A, Saleh S, Mehrotra S, Chan C, Sakamoto J. Augmenting protein release from layer-by-layer functionalized agarose hydrogels. Carbohydrate Polymers. 103: 377-84. PMID 24528743 DOI: 10.1016/j.carbpol.2013.12.069  1
2014 Cao Z, Zhang L, Chan CY, Ong HC. Interplay between absorption and radiative decay rates of surface plasmon polaritons for field enhancement in periodic arrays. Optics Letters. 39: 501-4. PMID 24487850 DOI: 10.1364/OL.39.000501  0.56
2014 Wu M, Chan C. Prediction of therapeutic microRNA based on the human metabolic network. Bioinformatics (Oxford, England). PMID 24403541 DOI: 10.1093/bioinformatics/btt751  0.72
2014 Malefyt AP, Wu M, Vocelle DB, Kappes SJ, Lindeman SD, Chan C, Walton SP. Improved asymmetry prediction for short interfering RNAs. The Febs Journal. 281: 320-30. PMID 24393396 DOI: 10.1111/febs.12599  1
2014 Liu L, Chan C. IPAF inflammasome is involved in interleukin-1β production from astrocytes, induced by palmitate; implications for Alzheimer's Disease. Neurobiology of Aging. 35: 309-21. PMID 24054992 DOI: 10.1016/j.neurobiolaging.2013.08.016  0.56
2013 Patil SP, Tran N, Geekiyanage H, Liu L, Chan C. Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons. Neuroscience Letters. 554: 121-5. PMID 24035895 DOI: 10.1016/j.neulet.2013.09.008  1
2013 Angart P, Vocelle D, Chan C, Walton SP. Design of siRNA Therapeutics from the Molecular Scale. Pharmaceuticals (Basel, Switzerland). 6: 440-68. PMID 23976875 DOI: 10.3390/ph6040440  0.72
2013 Liu L, Martin R, Kohler G, Chan C. Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes. Experimental Neurology. 248: 482-90. PMID 23968646 DOI: 10.1016/j.expneurol.2013.08.004  0.56
2013 Pan X, Whitten DA, Wu M, Chan C, Wilkerson CG, Pestka JJ. Early phosphoproteomic changes in the mouse spleen during deoxynivalenol-induced ribotoxic stress. Toxicological Sciences : An Official Journal of the Society of Toxicology. 135: 129-43. PMID 23811945 DOI: 10.1093/toxsci/kft145  0.72
2013 Wu M, Liu L, Hijazi H, Chan C. A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics (Oxford, England). 29: 1541-52. PMID 23610368 DOI: 10.1093/bioinformatics/btt186  0.72
2013 Geekiyanage H, Upadhye A, Chan C. Inhibition of serine palmitoyltransferase reduces Aβ and tau hyperphosphorylation in a murine model: a safe therapeutic strategy for Alzheimer's disease. Neurobiology of Aging. 34: 2037-51. PMID 23528227 DOI: 10.1016/j.neurobiolaging.2013.02.001  1
2013 Bilgin B, Liu L, Chan C, Walton SP. Quantitative, solution-phase profiling of multiple transcription factors in parallel. Analytical and Bioanalytical Chemistry. 405: 2461-8. PMID 23361227 DOI: 10.1007/s00216-013-6712-9  0.72
2013 Pan X, Whitten DA, Wu M, Chan C, Wilkerson CG, Pestka JJ. Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage. Toxicology and Applied Pharmacology. 268: 201-11. PMID 23352502 DOI: 10.1016/j.taap.2013.01.007  0.72
2013 Cho H, Wu M, Zhang L, Thompson R, Nath A, Chan C. Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells. Bmc Systems Biology. 7: 9. PMID 23339444 DOI: 10.1186/1752-0509-7-9  1
2013 Liu L, Martin R, Chan C. Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases. Neurobiology of Aging. 34: 540-50. PMID 22727944 DOI: 10.1016/j.neurobiolaging.2012.05.017  0.56
2012 Hijazi H, Wu M, Nath A, Chan C. Ensemble Classification of Cancer Types and Biomarker Identification. Drug Development Research. 73: 414-419. PMID 25221378 DOI: 10.1002/ddr.21032  0.72
2012 Wu M, Chan C. Human metabolic network: reconstruction, simulation, and applications in systems biology. Metabolites. 2: 242-53. PMID 24957377 DOI: 10.3390/metabo2010242  0.72
2012 Malefyt AP, Walton SP, Chan C. ENDOCYTOSIS PATHWAYS FOR NUCLEIC ACID THERAPEUTICS. Nano Life. 2: 1241005. PMID 23956796 DOI: 10.1142/S179398441241005X  0.72
2012 Cho H, Lamarca R, Chan C. Oligomerization of the transmembrane domain of IRE1α in SDS micelles. Biochemical and Biophysical Research Communications. 427: 764-7. PMID 23041190 DOI: 10.1016/j.bbrc.2012.09.135  0.72
2012 Cho H, Wu M, Bilgin B, Walton SP, Chan C. Latest developments in experimental and computational approaches to characterize protein-lipid interactions. Proteomics. 12: 3273-85. PMID 22997137 DOI: 10.1002/pmic.201200255  0.72
2012 Yang X, Chan C, Lam D, Schipper D, Stanley JM, Chen X, Jones RA, Holliday BJ, Wong WK, Chen S, Chen Q. Anion-dependent construction of two hexanuclear 3d-4f complexes with a flexible Schiff base ligand. Dalton Transactions (Cambridge, England : 2003). 41: 11449-53. PMID 22892983 DOI: 10.1039/c2dt31268a  0.4
2012 Zhang L, Chan CY, Li J, Ong HC. Rational design of high performance surface plasmon resonance sensors based on two-dimensional metallic hole arrays. Optics Express. 20: 12610-21. PMID 22714248 DOI: 10.1364/OE.20.012610  0.56
2012 Wu J, Zhang X, Zhang L, Wu CY, Rezaeian AH, Chan CH, Li JM, Wang J, Gao Y, Han F, Jeong YS, Yuan X, Khanna KK, Jin J, Zeng YX, et al. Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1. Molecular Cell. 46: 351-61. PMID 22464731 DOI: 10.1016/j.molcel.2012.02.018  1
2012 Geekiyanage H, Jicha GA, Nelson PT, Chan C. Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease. Experimental Neurology. 235: 491-6. PMID 22155483 DOI: 10.1016/j.expneurol.2011.11.026  1
2012 Wu M, Chan C. Learning transcriptional regulation on a genome scale: a theoretical analysis based on gene expression data. Briefings in Bioinformatics. 13: 150-61. PMID 21622543 DOI: 10.1093/bib/bbr029  0.72
2012 Mehrotra S, Lynam D, Liu C, Shahriari D, Lee I, Tuszynski M, Sakamoto J, Chan C. Time controlled release of arabinofuranosylcytosine (Ara-C) from agarose hydrogels using layer-by-layer assembly: an in vitro study. Journal of Biomaterials Science. Polymer Edition. 23: 439-63. PMID 21294967 DOI: 10.1163/092050610X552221  1
2011 Wang X, Nath A, Yang X, Portis A, Walton SP, Chan C. Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells. Plos One. 6: e28138. PMID 22132232 DOI: 10.1371/journal.pone.0028138  1
2011 Wu M, Liu L, Chan C. Identification of novel targets for breast cancer by exploring gene switches on a genome scale. Bmc Genomics. 12: 547. PMID 22053771 DOI: 10.1186/1471-2164-12-547  0.72
2011 Powell DA, Black WC, Bleasby K, Chan CC, Deschenes D, Gagnon M, Gordon R, Guay J, Guiral S, Hafey MJ, Huang Z, Isabel E, Leblanc Y, Styhler A, Xu LJ, et al. Nicotinic acids: liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy. Bioorganic & Medicinal Chemistry Letters. 21: 7281-6. PMID 22047692 DOI: 10.1016/j.bmcl.2011.10.040  0.4
2011 Geekiyanage H, Chan C. MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid β, novel targets in sporadic Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14820-30. PMID 21994399 DOI: 10.1523/JNEUROSCI.3883-11.2011  1
2011 Yang X, Lam D, Chan C, Stanley JM, Jones RA, Holliday BJ, Wong WK. Construction of 1-D 4f and 3d-4f coordination polymers with flexible Schiff base ligands. Dalton Transactions (Cambridge, England : 2003). 40: 9795-801. PMID 21874186 DOI: 10.1039/c1dt11036e  0.4
2011 Mehrotra S, Lee I, Liu C, Chan C. POLYELECTROLYTE MULTILAYER STAMPING IN AQUEOUS PHASE AND NON-CONTACT MODE. Industrial & Engineering Chemistry Research. 50: 8851-8858. PMID 21860540 DOI: 10.1021/ie102011m  1
2011 Oballa RM, Belair L, Black WC, Bleasby K, Chan CC, Desroches C, Du X, Gordon R, Guay J, Guiral S, Hafey MJ, Hamelin E, Huang Z, Kennedy B, Lachance N, et al. Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia. Journal of Medicinal Chemistry. 54: 5082-96. PMID 21661758 DOI: 10.1021/jm200319u  0.4
2011 Landry F, Chan CC, Huang Z, Leclair G, Li CS, Oballa R, Zhang L, Bateman K. Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors. Journal of Lipid Research. 52: 1494-9. PMID 21642745 DOI: 10.1194/jlr.M013177  1
2011 Cho H, Mukherjee S, Palasuberniam P, Pillow L, Bilgin B, Nezich C, Walton SP, Feig M, Chan C. Molecular mechanism by which palmitate inhibits PKR autophosphorylation. Biochemistry. 50: 1110-9. PMID 21192654 DOI: 10.1021/bi101923r  1
2011 Isabel E, Powell DA, Black WC, Chan CC, Crane S, Gordon R, Guay J, Guiral S, Huang Z, Robichaud J, Skorey K, Tawa P, Xu L, Zhang L, Oballa R. Biological activity and preclinical efficacy of azetidinyl pyridazines as potent systemically-distributed stearoyl-CoA desaturase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 479-83. PMID 21074991 DOI: 10.1016/j.bmcl.2010.10.107  0.4
2011 Zhang L, Seitz LC, Abramczyk AM, Liu L, Chan C. cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells. Cellular and Molecular Life Sciences : Cmls. 68: 863-76. PMID 20725762 DOI: 10.1007/s00018-010-0497-1  1
2010 Chan C, Yang X, Jones RA, Holliday BJ, Stanley JM. {μ-6,6'-Dimeth-oxy-2,2'-[butane-1,4-diylbis(nitrilo-methyl-idyne)]diphenolato-1:2κO,O,O,O:O,N,N',O}tris-(nitrato-1κO,O')copper(II)gadolinium(III). Acta Crystallographica. Section E, Structure Reports Online. 66: m576-7. PMID 21579057 DOI: 10.1107/S1600536810014716  0.4
2010 Walton SP, Wu M, Gredell JA, Chan C. Designing highly active siRNAs for therapeutic applications. The Febs Journal. 277: 4806-13. PMID 21078115 DOI: 10.1111/j.1742-4658.2010.07903.x  0.72
2010 Portis AM, Carballo G, Baker GL, Chan C, Walton SP. Confocal microscopy for the analysis of siRNA delivery by polymeric nanoparticles. Microscopy Research and Technique. 73: 878-85. PMID 20803695 DOI: 10.1002/jemt.20861  1
2010 Yang X, Nath A, Opperman MJ, Chan C. The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells. Molecular Biology of the Cell. 21: 3449-58. PMID 20685959 DOI: 10.1091/mbc.E10-06-0481  1
2010 Mehrotra S, Hunley SC, Pawelec KM, Zhang L, Lee I, Baek S, Chan C. Cell adhesive behavior on thin polyelectrolyte multilayers: cells attempt to achieve homeostasis of its adhesion energy. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 12794-802. PMID 20604583 DOI: 10.1021/la101689z  1
2010 Patil SP, Maki S, Khedkar SA, Rigby AC, Chan C. Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance. Journal of Natural Products. 73: 1196-202. PMID 20553006 DOI: 10.1021/np900633j  0.4
2010 Dalkic E, Wang X, Wright N, Chan C. Cancer-drug associations: a complex system. Plos One. 5: e10031. PMID 20368808 DOI: 10.1371/journal.pone.0010031  1
2010 Zhang L, Chan C. Isolation and enrichment of rat mesenchymal stem cells (MSCs) and separation of single-colony derived MSCs. Journal of Visualized Experiments : Jove. PMID 20308982 DOI: 10.3791/1852  1
2010 Mehrotra S, Lynam D, Maloney R, Pawelec KM, Tuszynski MH, Lee I, Chan C, Sakamoto J. Time Controlled Protein Release from Layer-by-Layer Assembled Multilayer Functionalized Agarose Hydrogels. Advanced Functional Materials. 20: 247-258. PMID 20200599 DOI: 10.1002/adfm.200901172  1
2010 Gredell JA, Dittmer MJ, Wu M, Chan C, Walton SP. Recognition of siRNA asymmetry by TAR RNA binding protein. Biochemistry. 49: 3148-55. PMID 20184375 DOI: 10.1021/bi902189s  0.72
2010 Ramtohul YK, Black C, Chan CC, Crane S, Guay J, Guiral S, Huang Z, Oballa R, Xu LJ, Zhang L, Li CS. SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 1593-7. PMID 20137926 DOI: 10.1016/j.bmcl.2010.01.083  0.4
2010 Zhang LS, Wong KH, Yip HY, Hu C, Yu JC, Chan CY, Wong PK. Effective photocatalytic disinfection of E. coli K-12 using AgBr-Ag-Bi2WO6 nanojunction system irradiated by visible light: the role of diffusing hydroxyl radicals. Environmental Science & Technology. 44: 1392-8. PMID 20085257 DOI: 10.1021/es903087w  0.64
2010 Zhang L, Seitz LC, Abramczyk AM, Chan C. Synergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells. Experimental Cell Research. 316: 716-27. PMID 20026039 DOI: 10.1016/j.yexcr.2009.12.008  1
2009 Williams P, Chan CC, Buggage R, Srivastava S, Callanan D. Pituitary adenoma presenting as bilateral bullous exudative retinal detachments: a clinicopathologic report. Retinal Cases & Brief Reports. 3: 230-2. PMID 25391084 DOI: 10.1097/ICB.0b013e31815f3cac  1
2009 Dalkic E, Nash DE, Fassia MK, Chan C. Integrative analysis of cancer pathway progression and coherence. Proteomics. Clinical Applications. 3: 473-85. PMID 21136972 DOI: 10.1002/prca.200800074  1
2009 Wu M, Yang X, Chan C. A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach. Plos One. 4: e8040. PMID 19956598 DOI: 10.1371/journal.pone.0008040  1
2009 Zhang LS, Wong KH, Zhang DQ, Hu C, Yu JC, Chan CY, Wong PK. Zn:In(OH)ySz solid solution nanoplates: synthesis, characterization, and photocatalytic mechanism. Environmental Science & Technology. 43: 7883-8. PMID 19921909 DOI: 10.1021/es902013d  0.64
2009 Yang X, Zhou Y, Jin R, Chan C. Reconstruct modular phenotype-specific gene networks by knowledge-driven matrix factorization. Bioinformatics (Oxford, England). 25: 2236-43. PMID 19542155 DOI: 10.1093/bioinformatics/btp376  1
2009 Leekumjorn S, Cho HJ, Wu Y, Wright NT, Sum AK, Chan C. The role of fatty acid unsaturation in minimizing biophysical changes on the structure and local effects of bilayer membranes. Biochimica Et Biophysica Acta. 1788: 1508-16. PMID 19371719 DOI: 10.1016/j.bbamem.2009.04.002  1
2009 Li Z, Chan C. Systems biology for identifying liver toxicity pathways. Bmc Proceedings. 3: S2. PMID 19278558  1
2009 Yang X, Chan C. Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2. Cell Research. 19: 469-86. PMID 19259124 DOI: 10.1038/cr.2009.25  1
2009 Mehrotra S, Lee I, Chan C. Multilayer mediated forward and patterned siRNA transfection using linear-PEI at extended N/P ratios. Acta Biomaterialia. 5: 1474-88. PMID 19217360 DOI: 10.1016/j.actbio.2009.01.004  0.68
2009 Li Z, He ML, Yao H, Dong QM, Chen YC, Chan CY, Zheng BJ, Yuen KY, Peng Y, Sun Q, Yang X, Lin MC, Sung JJ, Kung HF. Inhibition of HBV replication and gene expression in vitro and in vivo with a single AAV vector delivering two shRNA molecules. Bmb Reports. 42: 59-64. PMID 19192395  1
2008 Kidambi S, Lee I, Chan C. Primary Neuron/Astrocyte Co-Culture on Polyelectrolyte Multilayer Films: A Template for Studying Astrocyte-Mediated Oxidative Stress in Neurons. Advanced Functional Materials. 18: 294-301. PMID 25400537 DOI: 10.1002/adfm.200601237  1
2008 Srivastava S, Zhang L, Jin R, Chan C. A novel method incorporating gene ontology information for unsupervised clustering and feature selection. Plos One. 3: e3860. PMID 19052637 DOI: 10.1371/journal.pone.0003860  1
2008 Jin R, Si L, Chan C. A Bayesian framework for knowledge driven regression model in micro-array data analysis. International Journal of Data Mining and Bioinformatics. 2: 250-67. PMID 19024497  0.92
2008 Wang X, Dalkic E, Wu M, Chan C. Gene module level analysis: identification to networks and dynamics. Current Opinion in Biotechnology. 19: 482-91. PMID 18725293 DOI: 10.1016/j.copbio.2008.07.011  1
2008 Patil S, Balu D, Melrose J, Chan C. Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease. Bmc Research Notes. 1: 20. PMID 18710535 DOI: 10.1186/1756-0500-1-20  0.52
2008 Wang X, Wu M, Li Z, Chan C. Short time-series microarray analysis: methods and challenges. Bmc Systems Biology. 2: 58. PMID 18605994 DOI: 10.1186/1752-0509-2-58  1
2008 Li Z, Srivastava S, Findlan R, Chan C. Using dynamic gene module map analysis to identify targets that modulate free fatty acid induced cytotoxicity. Biotechnology Progress. 24: 29-37. PMID 18052188 DOI: 10.1021/bp070120b  1
2008 Kidambi S, Chan C, Lee I. Tunable resistive m-dPEG acid patterns on polyelectrolyte multilayers at physiological conditions: template for directed deposition of biomacromolecules. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 224-30. PMID 18052083 DOI: 10.1021/la702925r  1
2008 Srivastava S, Chan C. Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnology and Bioengineering. 99: 399-410. PMID 17615559 DOI: 10.1002/bit.21568  1
2007 Srivastava S, Li Z, Yang X, Yedwabnick M, Shaw S, Chan C. Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells. Bmc Genomics. 8: 364. PMID 17925029 DOI: 10.1186/1471-2164-8-364  1
2007 Patil S, Melrose J, Chan C. Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons. The European Journal of Neuroscience. 26: 2131-41. PMID 17908174 DOI: 10.1111/j.1460-9568.2007.05797.x  0.52
2007 Zhang X, Kong B, Tsui OK, Yang X, Mi Y, Chan CM, Xu B. Effect of pattern topology on the self-cleaning properties of textured surfaces. The Journal of Chemical Physics. 127: 014703. PMID 17627360 DOI: 10.1063/1.2748383  0.4
2007 Li Z, Srivastava S, Mittal S, Yang X, Sheng L, Chan C. A Three Stage Integrative Pathway Search (TIPS) framework to identify toxicity relevant genes and pathways. Bmc Bioinformatics. 8: 202. PMID 17570844 DOI: 10.1186/1471-2105-8-202  1
2007 Kidambi S, Udpa N, Schroeder SA, Findlan R, Lee I, Chan C. Cell adhesion on polyelectrolyte multilayer coated polydimethylsiloxane surfaces with varying topographies. Tissue Engineering. 13: 2105-17. PMID 17518734 DOI: 10.1089/ten.2006.0151  1
2007 Li Z, Srivastava S, Yang X, Mittal S, Norton P, Resau J, Haab B, Chan C. A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells. Bmc Systems Biology. 1: 21. PMID 17498300 DOI: 10.1186/1752-0509-1-21  1
2007 Kidambi S, Sheng L, Yarmush ML, Toner M, Lee I, Chan C. Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates. Macromolecular Bioscience. 7: 344-53. PMID 17370273 DOI: 10.1002/mabi.200600205  1
2007 Srivastava S, Chan C. Hydrogen peroxide and hydroxyl radicals mediate palmitate-induced cytotoxicity to hepatoma cells: relation to mitochondrial permeability transition. Free Radical Research. 41: 38-49. PMID 17164177 DOI: 10.1080/10715760600943900  1
2006 Jin R, Si L, Srivastava S, Li Z, Chan C. A knowledge driven regression model for gene expression and microarray analysis. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 5326-9. PMID 17945892 DOI: 10.1109/IEMBS.2006.260347  1
2006 Patil S, Li Z, Chan C. Cellular to tissue informatics: approaches to optimizing cellular function of engineered tissue. Advances in Biochemical Engineering/Biotechnology. 102: 139-59. PMID 17089789  1
2006 Patil S, Sheng L, Masserang A, Chan C. Palmitic acid-treated astrocytes induce BACE1 upregulation and accumulation of C-terminal fragment of APP in primary cortical neurons. Neuroscience Letters. 406: 55-9. PMID 16904262 DOI: 10.1016/j.neulet.2006.07.015  0.64
2006 Huang Z, Liu S, Zhang L, Salem M, Greig GM, Chan CC, Natsumeda Y, Noguchi K. Preferential inhibition of human phosphodiesterase 4 by ibudilast. Life Sciences. 78: 2663-8. PMID 16313925 DOI: 10.1016/j.lfs.2005.10.026  1
2004 Kidambi S, Lee I, Chan C. Controlling primary hepatocyte adhesion and spreading on protein-free polyelectrolyte multilayer films. Journal of the American Chemical Society. 126: 16286-7. PMID 15600306 DOI: 10.1021/ja046188u  1
2004 Kidambi S, Chan C, Lee I. Selective depositions on polyelectrolyte multilayers: self-assembled monolayers of m-dPEG acid as molecular template. Journal of the American Chemical Society. 126: 4697-703. PMID 15070388 DOI: 10.1021/ja039359o  1
2003 Nussenblatt RB, Thompson DJ, Li Z, Chan CC, Peterson JS, Robinson RR, Shames RS, Nagarajan S, Tang MT, Mailman M, Velez G, Roy C, Levy-Clarke GA, Suhler EB, Djalilian A, et al. Humanized anti-interleukin-2 (IL-2) receptor alpha therapy: long-term results in uveitis patients and preliminary safety and activity data for establishing parameters for subcutaneous administration. Journal of Autoimmunity. 21: 283-93. PMID 14599854 DOI: 10.1016/S0896-8411(03)00113-6  1
2003 Chan CC. In vivo assays for COX-2 Methods in Molecular Biology (Clifton, N.J.). 225: 321-328. PMID 12769499  0.4
2003 Chan CW, Kay LS, Khadaroo RG, Chan MW, Lakatoo S, Young KJ, Zhang L, Gorczynski RM, Cattral M, Rotstein O, Levy GA. Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: suppressing T cell proliferation and inhibiting maturation of bone marrow-derived dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4036-44. PMID 12682232  1
2002 Mehta S, Yang XM, Chan CS, Dobson MJ, Jayaram M, Velmurugan S. The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation? The Journal of Cell Biology. 158: 625-37. PMID 12177044 DOI: 10.1083/jcb.200204136  0.4
2001 Tang ZK, Zhang L, Wang N, Zhang XX, Wen GH, Li GD, Wang JN, Chan CT, Sheng P. Superconductivity in 4 angstrom single-walled carbon nanotubes. Science (New York, N.Y.). 292: 2462-5. PMID 11431560 DOI: 10.1126/science.1060470  1
2001 Xin B, He Z, Yang X, Chan CP, Ng MH, Cao L. TRADD domain of Epstein-Barr virus transforming protein LMP1 is essential for inducing immortalization and suppressing senescence of primary rodent fibroblasts. Journal of Virology. 75: 3010-5. PMID 11222727 DOI: 10.1128/JVI.75.6.3010-3015.2001  0.36
2000 Velmurugan S, Yang XM, Chan CS, Dobson M, Jayaram M. Partitioning of the 2-microm circle plasmid of Saccharomyces cerevisiae. Functional coordination with chromosome segregation and plasmid-encoded rep protein distribution. The Journal of Cell Biology. 149: 553-66. PMID 10791970 DOI: 10.1083/jcb.149.3.553  0.4
2000 He Z, Xin B, Yang X, Chan C, Cao L. Nuclear factor-kappaB activation is involved in LMP1-mediated transformation and tumorigenesis of rat-1 fibroblasts. Cancer Research. 60: 1845-8. PMID 10766170  0.36
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