Oliver Fiehn - Publications

Affiliations: 
Biochemistry and Molecular Biology University of California, Davis, Davis, CA 
Area:
Biochemistry, Analytical Chemistry, Molecular Biology, Cell Biology, Nutrition

243 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Barupal DK, Fiehn O. Generating the Blood Exposome Database Using a Comprehensive Text Mining and Database Fusion Approach. Environmental Health Perspectives. 127: 97008. PMID 31557052 DOI: 10.1289/EHP4713  0.4
2019 Grapov D, Fiehn O, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Hoppel CL, Harper ME, Adams SH. Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: impact of a fitness and weight loss intervention. American Journal of Physiology. Endocrinology and Metabolism. PMID 31526287 DOI: 10.1152/ajpendo.00091.2019  0.52
2019 Barupal DK, Baillie R, Fan S, Saykin AJ, Meikle PJ, Arnold M, Nho K, Fiehn O, Kaddurah-Daouk R. Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 619-627. PMID 31517024 DOI: 10.1016/j.dadm.2019.07.002  0.4
2019 Barupal DK, Gao B, Budczies J, Phinney BS, Perroud B, Denkert C, Fiehn O. Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining. Oncotarget. 10: 3894-3909. PMID 31231467 DOI: 10.18632/oncotarget.26995  0.4
2019 Barupal DK, Zhang Y, Shen T, Fan S, Roberts BS, Fitzgerald P, Wancewicz B, Valdiviez L, Wohlgemuth G, Byram G, Choy YY, Haffner B, Showalter MR, Vaniya A, Bloszies CS, ... ... Fiehn O, et al. A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium. Metabolites. 9. PMID 31121816 DOI: 10.3390/metabo9050101  0.4
2019 Fan S, Kind T, Cajka T, Hazen SL, Tang WHW, Kaddurah-Daouk R, Irvin MR, Arnett DK, Barupal DK, Fiehn O. Systematic Error Removal using Random Forest (SERRF) for Normalizing Large-Scale Untargeted Lipidomics Data. Analytical Chemistry. PMID 30758187 DOI: 10.1021/acs.analchem.8b05592  0.4
2019 Hook V, Kind T, Podvin S, Palazoglu M, Tran C, Toneff T, Samra S, Lietz C, Fiehn O. Metabolomics Analyses of 14 Classical Neurotransmitters by GC-TOF with LC-MS Illustrates Secretion of 9 Cell-Cell Signaling Molecules from Sympathoadrenal Chromaffin Cells in the Presence of Lithium. Acs Chemical Neuroscience. PMID 30698015 DOI: 10.1021/acschemneuro.8b00432  0.4
2019 Blaženović I, Kind T, Sa MR, Ji J, Vaniya A, Wancewicz B, Roberts BS, Torbasinovic H, Lee T, Mehta SS, Showalter MR, Song H, Kwok JF, Jahn D, Kim J, ... Fiehn O, et al. Structure annotation of all mass spectra in untargeted metabolomics. Analytical Chemistry. PMID 30608141 DOI: 10.1021/acs.analchem.8b04698  0.4
2018 Barupal DK, Fan S, Wancewicz B, Cajka T, Sa M, Showalter MR, Baillie R, Tenenbaum JD, Louie G, Kaddurah-Daouk R, Fiehn O. Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort. Scientific Data. 5: 180263. PMID 31745199 DOI: 10.1038/sdata.2018.263  0.4
2018 Barupal DK, Fan S, Wancewicz B, Cajka T, Sa M, Showalter MR, Baillie R, Tenenbaum JD, Louie G, Kaddurah-Daouk R, Fiehn O. Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort. Scientific Data. 5: 180263. PMID 30457571 DOI: 10.1038/sdata.2018.263  0.4
2018 Zhang J, Bhattacharyya S, Hickner RC, Light AR, Lambert CJ, Gale BK, Fiehn O, Adams SH. Skeletal muscle interstitial fluid metabolomics at rest and associated with an exercise bout: application in rats and humans. American Journal of Physiology. Endocrinology and Metabolism. PMID 30398905 DOI: 10.1152/ajpendo.00156.2018  0.52
2018 Blaženović I, Shen T, Mehta SS, Kind T, Ji J, Piparo M, Cacciola F, Mondello L, Fiehn O. Increasing Compound Identification Rates in Untargeted Lipidomics Research with Liquid Chromatography Drift Time-Ion Mobility Mass Spectrometry. Analytical Chemistry. PMID 30096227 DOI: 10.1021/acs.analchem.8b01527  0.4
2018 Nagy-Szakal D, Barupal DK, Lee B, Che X, Williams BL, Kahn EJR, Ukaigwe JE, Bateman L, Klimas NG, Komaroff AL, Levine S, Montoya JG, Peterson DL, Levin B, Hornig M, ... Fiehn O, et al. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific Reports. 8: 10056. PMID 29968805 DOI: 10.1038/s41598-018-28477-9  0.4
2018 Blaženović I, Kind T, Ji J, Fiehn O. Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics. Metabolites. 8. PMID 29748461 DOI: 10.3390/metabo8020031  0.4
2018 Barupal DK, Fan S, Fiehn O. Integrating bioinformatics approaches for a comprehensive interpretation of metabolomics datasets. Current Opinion in Biotechnology. 54: 1-9. PMID 29413745 DOI: 10.1016/j.copbio.2018.01.010  0.4
2017 Kind T, Fiehn O. Strategies for dereplication of natural compounds using high-resolution tandem mass spectrometry. Phytochemistry Letters. 21: 313-319. PMID 29225718 DOI: 10.1016/j.phytol.2016.11.006  0.4
2017 Lai Z, Tsugawa H, Wohlgemuth G, Mehta S, Mueller M, Zheng Y, Ogiwara A, Meissen J, Showalter M, Takeuchi K, Kind T, Beal P, Arita M, Fiehn O. Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics. Nature Methods. PMID 29176591 DOI: 10.1038/nmeth.4512  0.4
2017 Fong LY, Jing R, Smalley KJ, Taccioli C, Fahrmann J, Barupal DK, Alder H, Farber JL, Fiehn O, Croce CM. Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia. Oncotarget. 8: 81910-81925. PMID 29137232 DOI: 10.18632/oncotarget.18434  0.4
2017 Barupal DK, Fiehn O. Chemical Similarity Enrichment Analysis (ChemRICH) as alternative to biochemical pathway mapping for metabolomic datasets. Scientific Reports. 7: 14567. PMID 29109515 DOI: 10.1038/s41598-017-15231-w  0.4
2017 Schymanski EL, Ruttkies C, Krauss M, Brouard C, Kind T, Dührkop K, Allen F, Vaniya A, Verdegem D, Böcker S, Rousu J, Shen H, Tsugawa H, Sajed T, Fiehn O, et al. Critical Assessment of Small Molecule Identification 2016: automated methods. Journal of Cheminformatics. 9: 22. PMID 29086042 DOI: 10.1186/s13321-017-0207-1  0.4
2017 Blaženović I, Kind T, Torbašinović H, Obrenović S, Mehta SS, Tsugawa H, Wermuth T, Schauer N, Jahn M, Biedendieck R, Jahn D, Fiehn O. Comprehensive comparison of in silico MS/MS fragmentation tools of the CASMI contest: database boosting is needed to achieve 93% accuracy. Journal of Cheminformatics. 9: 32. PMID 29086039 DOI: 10.1186/s13321-017-0219-x  0.4
2017 Lai Z, Kind T, Fiehn O. Using Accurate Mass Gas Chromatography - Mass Spectrometry with the MINE Database for Epimetabolite Annotation. Analytical Chemistry. PMID 28876899 DOI: 10.1021/acs.analchem.7b01134  0.4
2017 Fong LY, Jing R, Smalley KJ, Taccioli C, Fahrmann J, Barupal DK, Alder H, Farber JL, Fiehn O, Croce CM. Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia. Oncotarget. PMID 28622688 DOI: 10.18632/oncotarget.18434  0.4
2017 Kind T, Tsugawa H, Cajka T, Ma Y, Lai Z, Mehta SS, Wohlgemuth G, Barupal DK, Showalter MR, Arita M, Fiehn O. Identification of small molecules using accurate mass MS/MS search. Mass Spectrometry Reviews. PMID 28436590 DOI: 10.1002/mas.21535  0.4
2017 Wanichthanarak K, Fan S, Grapov D, Barupal DK, Fiehn O. Metabox: A Toolbox for Metabolomic Data Analysis, Interpretation and Integrative Exploration. Plos One. 12: e0171046. PMID 28141874 DOI: 10.1371/journal.pone.0171046  0.4
2016 Kind T, Cho E, Park TD, Deng N, Liu Z, Lee T, Fiehn O, Kim J. Interstitial Cystitis-Associated Urinary Metabolites Identified by Mass-Spectrometry Based Metabolomics Analysis. Scientific Reports. 6: 39227. PMID 27976711 DOI: 10.1038/srep39227  0.4
2016 Aguer C, Piccolo BD, Fiehn O, Adams SH, Harper ME. A novel amino acid and metabolomics signature in mice overexpressing muscle uncoupling protein 3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27871066 DOI: 10.1096/fj.201600914R  0.52
2016 Barupal DK, Pinkerton KE, Hood C, Kind T, Fiehn O. Environmental tobacco smoke alters metabolic systems in adult rats. Chemical Research in Toxicology. PMID 27788581 DOI: 10.1021/acs.chemrestox.6b00187  0.4
2016 Zhang J, Light AR, Hoppel CL, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Hughen RW, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, ... Fiehn O, et al. Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons. Experimental Physiology. PMID 27730694 DOI: 10.1113/EP086019  0.52
2016 Lai Z, Fiehn O. Mass spectral fragmentation of trimethylsilylated small molecules. Mass Spectrometry Reviews. PMID 27580014 DOI: 10.1002/mas.21518  0.92
2016 Tsugawa H, Kind T, Nakabayashi R, Yukihira D, Tanaka W, Cajka T, Saito K, Fiehn O, Arita M. Hydrogen rearrangement rules: computational MS/MS fragmentation and structure elucidation using MS-FINDER software. Analytical Chemistry. PMID 27419259 DOI: 10.1021/acs.analchem.6b00770  0.4
2016 Shahin MH, Gong Y, McDonough CW, Rotroff DM, Beitelshees AL, Garrett TJ, Gums JG, Motsinger-Reif A, Chapman AB, Turner ST, Boerwinkle E, Frye RF, Fiehn O, Cooper-DeHoff RM, Kaddurah-Daouk R, et al. A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. Hypertension. PMID 27381900 DOI: 10.1161/HYPERTENSIONAHA.116.07328  0.92
2016 Huang L, Khusnutdinova A, Nocek B, Brown G, Xu X, Cui H, Petit P, Flick R, Zallot R, Balmant K, Ziemak MJ, Shanklin J, de Crécy-Lagard V, Fiehn O, Gregory JF, et al. A family of metal-dependent phosphatases implicated in metabolite damage-control. Nature Chemical Biology. PMID 27322068 DOI: 10.1038/nchembio.2108  0.92
2016 Thiaville JJ, Flood J, Yurgel S, Prunetti L, Elbadawi-Sidhu M, Hutinet G, Forouhar F, Zhang X, Ganesan V, Reddy P, Fiehn O, Gerlt JA, Hunt JF, Copley SD, De Crecy-Lagard V. Members of a novel kinase family (DUF1537) can recycle toxic intermediates into an essential metabolite. Acs Chemical Biology. PMID 27294475 DOI: 10.1021/acschembio.6b00279  0.92
2016 Albrecht U, Fiehn O, Bowman KD. Metabolic variations in different citrus rootstock cultivars associated with different responses to Huanglongbing. Plant Physiology and Biochemistry : Ppb / Societe Francaise De Physiologie Vegetale. 107: 33-44. PMID 27236226 DOI: 10.1016/j.plaphy.2016.05.030  0.92
2016 Karakas SE, Perroud B, Kind T, Palazoglu M, Fiehn O. Changes in plasma metabolites and glucose homeostasis during omega-3 polyunsaturated fatty acid supplementation in women with polycystic ovary syndrome. Bba Clinical. 5: 179-85. PMID 27182493 DOI: 10.1016/j.bbacli.2016.04.003  0.92
2016 Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fienh O, Xu J, Kung HJ, Murphy L, Chen HW. Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes. Cancer Letters. PMID 27164560 DOI: 10.1016/j.canlet.2016.05.004  0.92
2016 Yui Y, Miyazaki S, Ma Y, Ohira M, Fiehn O, Ikegami T, McCalley DV, Tanaka N. Distinction of synthetic dl-α-tocopherol from natural vitamin E (d-α-tocopherol) by reversed-phase liquid chromatography. Enhanced selectivity of a polymeric C18 stationary phase at low temperature and/or at high pressure. Journal of Chromatography. A. PMID 27157422 DOI: 10.1016/j.chroma.2016.04.076  0.92
2016 Piccolo BD, Graham JL, Stanhope KL, Fiehn O, Havel PJ, Adams SH. Plasma amino acid and metabolite signatures tracking diabetes progression in the UCD-T2DM Rat model of type 2 diabetes. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00052.2016. PMID 27094034 DOI: 10.1152/ajpendo.00052.2016  0.52
2016 Garay LA, Sitepu IR, Cajka T, Chandra I, Shi S, Lin T, German JB, Fiehn O, Boundy-Mills KL. Eighteen new oleaginous yeast species. Journal of Industrial Microbiology & Biotechnology. PMID 27072563 DOI: 10.1007/s10295-016-1765-3  0.92
2016 Fahrmann JF, Grapov DD, DeFelice BC, Taylor S, Kim K, Kelly K, Wikoff WR, Pass H, Rom WN, Fiehn O, Miyamoto S. Serum phosphatidylethanolamine levels distinguish benign from malignant solitary pulmonary nodules and represent a potential diagnostic biomarker for lung cancer. Cancer Biomarkers : Section a of Disease Markers. PMID 27002763 DOI: 10.3233/CBM-160602  0.92
2016 Venkatesh TV, Chassy AW, Fiehn O, Flint-Garcia S, Zeng Q, Skogerson K, Harrigan GG. Metabolomic assessment of key maize resources: GC-MS and NMR profiling of grain from B73 hybrids of the nested association mapping (NAM) founders and of geographically diverse landraces. Journal of Agricultural and Food Chemistry. PMID 26923484 DOI: 10.1021/acs.jafc.5b04901  0.92
2016 Prunetti L, El Yacoubi B, Schiavon CR, Kirkpatrick E, Huang L, Bailly M, ElBadawi-Sidhu M, Harrison K, Gregory JF, Fiehn O, Hanson AD, de Crécy-Lagard V. Evidence That COG0325 Proteins are involved in PLP Homeostasis. Microbiology (Reading, England). PMID 26872910 DOI: 10.1099/mic.0.000255  0.92
2016 Cajka T, Fiehn O. Toward Merging Untargeted and Targeted Methods in Mass Spectrometry-Based Metabolomics and Lipidomics. Analytical Chemistry. 88: 524-45. PMID 26637011 DOI: 10.1021/acs.analchem.5b04491  0.92
2016 Higgins BT, Gennity I, Samra S, Kind T, Fiehn O, VanderGheynst JS. Cofactor symbiosis for enhanced algal growth, biofuel production, and wastewater treatment Algal Research. 17: 308-315. DOI: 10.1016/j.algal.2016.05.024  0.92
2016 Cajka T, Fiehn O. Increasing lipidomic coverage by selecting optimal mobile-phase modifiers in LC–MS of blood plasma Metabolomics. 12: 1-11. DOI: 10.1007/s11306-015-0929-x  0.92
2015 Ma Y, Tanaka N, Vaniya A, Kind T, Fiehn O. Ultrafast polyphenol metabolomics of red wines using microLC-MS/MS. Journal of Agricultural and Food Chemistry. PMID 26698107 DOI: 10.1021/acs.jafc.5b04890  0.92
2015 Hanson AD, Henry CS, Fiehn O, de Crécy-Lagard V. Metabolite Damage and Metabolite Damage Control in Plants. Annual Review of Plant Biology. PMID 26667673 DOI: 10.1146/annurev-arplant-043015-111648  0.92
2015 Ma Y, Kind T, Vaniya A, Gennity I, Fahrmann JF, Fiehn O. An in silico MS/MS library for automatic annotation of novel FAHFA lipids. Journal of Cheminformatics. 7: 53. PMID 26579213 DOI: 10.1186/s13321-015-0104-4  0.92
2015 Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, ... ... Fiehn O, et al. The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nature Cell Biology. PMID 26571212 DOI: 10.1038/ncb3264  0.92
2015 Sud M, Fahy E, Cotter D, Azam K, Vadivelu I, Burant C, Edison A, Fiehn O, Higashi R, Nair KS, Sumner S, Subramaniam S. Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools. Nucleic Acids Research. PMID 26467476 DOI: 10.1093/nar/gkv1042  0.92
2015 Yang D, Song D, Kind T, Ma Y, Hoefkens J, Fiehn O. Lipidomic Analysis of Chlamydomonas reinhardtii under Nitrogen and Sulfur Deprivation. Plos One. 10: e0137948. PMID 26375463 DOI: 10.1371/journal.pone.0137948  0.92
2015 Jeffryes JG, Colastani RL, Elbadawi-Sidhu M, Kind T, Niehaus TD, Broadbelt LJ, Hanson AD, Fiehn O, Tyo KE, Henry CS. MINEs: open access databases of computationally predicted enzyme promiscuity products for untargeted metabolomics. Journal of Cheminformatics. 7: 44. PMID 26322134 DOI: 10.1186/s13321-015-0087-1  0.92
2015 Abate-Pella D, Freund DM, Ma Y, Simón-Manso Y, Hollender J, Broeckling CD, Huhman DV, Krokhin OV, Stoll DR, Hegeman AD, Kind T, Fiehn O, Schymanski EL, Prenni JE, Sumner LW, et al. Retention projection enables accurate calculation of liquid chromatographic retention times across labs and methods. Journal of Chromatography. A. 1412: 43-51. PMID 26292625 DOI: 10.1016/j.chroma.2015.07.108  0.92
2015 Wikoff WR, Hanash S, DeFelice B, Miyamoto S, Barnett M, Zhao Y, Goodman G, Feng Z, Gandara D, Fiehn O, Taguchi A. Diacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26282655 DOI: 10.1200/JCO.2015.61.7779  0.92
2015 Fahrmann JF, Kim K, DeFelice BC, Taylor SL, Gandara DR, Yoneda KY, Cooke DT, Fiehn O, Kelly K, Miyamoto S. Investigation of Metabolomic Blood Biomarkers for Detection of Adenocarcinoma Lung Cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26282632 DOI: 10.1158/1055-9965.EPI-15-0427  0.92
2015 Vaniya A, Fiehn O. Using fragmentation trees and mass spectral trees for identifying unknown compounds in metabolomics. Trends in Analytical Chemistry : Trac. 69: 52-61. PMID 26213431 DOI: 10.1016/j.trac.2015.04.002  0.92
2015 Meissen JK, Hirahatake KM, Adams SH, Fiehn O. Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures. Metabolomics : Official Journal of the Metabolomic Society. 11: 707-721. PMID 26190955 DOI: 10.1007/s11306-014-0729-8  0.92
2015 Solloway MJ, Madjidi A, Gu C, Eastham-Anderson J, Clarke HJ, Kljavin N, Zavala-Solorio J, Kates L, Friedman B, Brauer M, Wang J, Fiehn O, Kolumam G, Stern H, Lowe JB, et al. Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass. Cell Reports. PMID 26166562 DOI: 10.1016/j.celrep.2015.06.034  0.92
2015 Liesenfeld DB, Grapov D, Fahrmann JF, Salou M, Scherer D, Toth R, Habermann N, Böhm J, Schrotz-King P, Gigic B, Schneider M, Ulrich A, Herpel E, Schirmacher P, Fiehn O, et al. Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study. The American Journal of Clinical Nutrition. 102: 433-43. PMID 26156741 DOI: 10.3945/ajcn.114.103804  0.92
2015 Niehaus TD, Gerdes S, Hodge-Hanson K, Zhukov A, Cooper AJ, ElBadawi-Sidhu M, Fiehn O, Downs DM, Hanson AD. Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family. Bmc Genomics. 16: 382. PMID 25975565 DOI: 10.1186/s12864-015-1584-3  0.92
2015 Tsugawa H, Cajka T, Kind T, Ma Y, Higgins B, Ikeda K, Kanazawa M, VanderGheynst J, Fiehn O, Arita M. MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis. Nature Methods. 12: 523-6. PMID 25938372 DOI: 10.1038/nmeth.3393  0.92
2015 Miyamoto S, Taylor SL, Barupal DK, Taguchi A, Wohlgemuth G, Wikoff WR, Yoneda KY, Gandara DR, Hanash SM, Kim K, Fiehn O. Systemic Metabolomic Changes in Blood Samples of Lung Cancer Patients Identified by Gas Chromatography Time-of-Flight Mass Spectrometry. Metabolites. 5: 192-210. PMID 25859693 DOI: 10.3390/metabo5020192  0.4
2015 Fahrmann J, Grapov D, Yang J, Hammock B, Fiehn O, Bell GI, Hara M. Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia. American Journal of Physiology. Endocrinology and Metabolism. 308: E978-89. PMID 25852003 DOI: 10.1152/ajpendo.00019.2015  0.92
2015 Grapov D, Wanichthanarak K, Fiehn O. MetaMapR: pathway independent metabolomic network analysis incorporating unknowns. Bioinformatics (Oxford, England). 31: 2757-60. PMID 25847005 DOI: 10.1093/bioinformatics/btv194  0.92
2015 Piccolo BD, Comerford KB, Karakas SE, Knotts TA, Fiehn O, Adams SH. Whey protein supplementation does not alter plasma branched-chained amino acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial. The Journal of Nutrition. 145: 691-700. PMID 25833773 DOI: 10.3945/jn.114.203943  0.92
2015 Piccolo BD, Keim NL, Fiehn O, Adams SH, Van Loan MD, Newman JW. Habitual physical activity and plasma metabolomic patterns distinguish individuals with low vs. high weight loss during controlled energy restriction. The Journal of Nutrition. 145: 681-90. PMID 25833772 DOI: 10.3945/jn.114.201574  0.92
2015 Kaysen GA, Johansen KL, Chertow GM, Dalrymple LS, Kornak J, Grimes B, Dwyer T, Chassy AW, Fiehn O. Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis. Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation. 25: 351-6. PMID 25802017 DOI: 10.1053/j.jrn.2015.02.006  0.92
2015 Grapov D, Fahrmann J, Hwang J, Poudel A, Jo J, Periwal V, Fiehn O, Hara M. Diabetes Associated Metabolomic Perturbations in NOD Mice. Metabolomics : Official Journal of the Metabolomic Society. 11: 425-437. PMID 25755629 DOI: 10.1007/s11306-014-0706-2  0.92
2015 Kim T, Dreher K, Nilo-Poyanco R, Lee I, Fiehn O, Lange BM, Nikolau BJ, Sumner L, Welti R, Wurtele ES, Rhee SY. Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis using a genome-scale metabolic network. Plant Physiology. 167: 1685-98. PMID 25670818 DOI: 10.1104/pp.114.252361  0.92
2015 Wikoff WR, Grapov D, Fahrmann JF, DeFelice B, Rom WN, Pass HI, Kim K, Nguyen U, Taylor SL, Gandara DR, Kelly K, Fiehn O, Miyamoto S. Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma. Cancer Prevention Research (Philadelphia, Pa.). 8: 410-8. PMID 25657018 DOI: 10.1158/1940-6207.CAPR-14-0329  0.92
2015 Ma Y, Chassy AW, Miyazaki S, Motokawa M, Morisato K, Uzu H, Ohira M, Furuno M, Nakanishi K, Minakuchi H, Mriziq K, Farkas T, Fiehn O, Tanaka N. Efficiency of short, small-diameter columns for reversed-phase liquid chromatography under practical operating conditions. Journal of Chromatography. A. 1383: 47-57. PMID 25648581 DOI: 10.1016/j.chroma.2015.01.014  0.92
2015 Glenn DJ, Cardema MC, Ni W, Zhang Y, Yeghiazarians Y, Grapov D, Fiehn O, Gardner DG. Cardiac steatosis potentiates angiotensin II effects in the heart. American Journal of Physiology. Heart and Circulatory Physiology. 308: H339-50. PMID 25485904 DOI: 10.1152/ajpheart.00742.2014  0.92
2015 Budczies J, Pfitzner BM, Györffy B, Winzer KJ, Radke C, Dietel M, Fiehn O, Denkert C. Glutamate enrichment as new diagnostic opportunity in breast cancer. International Journal of Cancer. 136: 1619-28. PMID 25155347 DOI: 10.1002/ijc.29152  0.92
2015 Higgins BT, Nobles D, Ma Y, Wikoff W, Kind T, Fiehn O, Brand J, VanderGheynst JS. Informatics for improved algal taxonomic classification and research: A case study of UTEX 2341 Algal Research. 12: 545-549. DOI: 10.1016/j.algal.2015.10.016  0.92
2015 Fiehn O, Putri SP, Saito K, Salek RM, Creek DJ. Metabolomics continues to expand: highlights from the 2015 metabolomics conference Metabolomics. 11: 1036-1040. DOI: 10.1007/s11306-015-0846-z  0.92
2015 Cheung WHK, Pasamontes A, Peirano DJ, Zhao W, Grafton-Cardwell EE, Kapaun T, Yokomi RK, Simmons J, Doll M, Fiehn O, Dandekar AM, Davis CE. Volatile organic compound (VOC) profiling of citrus tristeza virus infection in sweet orange citrus varietals using thermal desorption gas chromatography time of flight mass spectrometry (TD-GC/TOF-MS) Metabolomics. DOI: 10.1007/s11306-015-0807-6  0.92
2014 Armstrong AW, Wu J, Johnson MA, Grapov D, Azizi B, Dhillon J, Fiehn O. Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. F1000research. 3: 248. PMID 25580230 DOI: 10.12688/f1000research.4709.1  0.92
2014 Tay-Sontheimer J, Shireman LM, Beyer RP, Senn T, Witten D, Pearce RE, Gaedigk A, Gana Fomban CL, Lutz JD, Isoherranen N, Thummel KE, Fiehn O, Leeder JS, Lin YS. Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics. Pharmacogenomics. 15: 1947-62. PMID 25521354 DOI: 10.2217/pgs.14.155  0.92
2014 Snowden SG, Grapov D, Settergren M, D'Alexandri FL, Haeggström JZ, Fiehn O, Hyötyläinen T, Pedersen TL, Newman JW, Oreši? M, Pernow J, Wheelock CE. High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy. Circulation. Cardiovascular Genetics. 7: 955-64. PMID 25516625 DOI: 10.1161/CIRCGENETICS.114.000606  0.92
2014 Su LJ, Fiehn O, Maruvada P, Moore SC, O'Keefe SJ, Wishart DS, Zanetti KA. The use of metabolomics in population-based research. Advances in Nutrition (Bethesda, Md.). 5: 785-8. PMID 25398741 DOI: 10.3945/an.114.006494  0.92
2014 He Y, Hogrefe CE, Grapov D, Palazoglu M, Fiehn O, Turck CW, Golub MS. Identifying individual differences of fluoxetine response in juvenile rhesus monkeys by metabolite profiling. Translational Psychiatry. 4: e478. PMID 25369145 DOI: 10.1038/tp.2014.116  0.92
2014 Kind T, Okazaki Y, Saito K, Fiehn O. LipidBlast templates as flexible tools for creating new in-silico tandem mass spectral libraries. Analytical Chemistry. 86: 11024-7. PMID 25340521 DOI: 10.1021/ac502511a  0.92
2014 Cajka T, Fiehn O. Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry. Trends in Analytical Chemistry : Trac. 61: 192-206. PMID 25309011 DOI: 10.1016/j.trac.2014.04.017  0.92
2014 Fiehn O, Kim J. Metabolomics insights into pathophysiological mechanisms of interstitial cystitis. International Neurourology Journal. 18: 106-14. PMID 25279237 DOI: 10.5213/inj.2014.18.3.106  0.92
2014 Ma Y, Kind T, Yang D, Leon C, Fiehn O. MS2Analyzer: A software for small molecule substructure annotations from accurate tandem mass spectra. Analytical Chemistry. 86: 10724-31. PMID 25263576 DOI: 10.1021/ac502818e  0.92
2014 Lee do Y, Kind T, Yoon YR, Fiehn O, Liu KH. Comparative evaluation of extraction methods for simultaneous mass-spectrometric analysis of complex lipids and primary metabolites from human blood plasma. Analytical and Bioanalytical Chemistry. 406: 7275-86. PMID 25171832 DOI: 10.1007/s00216-014-8124-x  0.92
2014 Niehaus TD, Nguyen TN, Gidda SK, ElBadawi-Sidhu M, Lambrecht JA, McCarty DR, Downs DM, Cooper AJ, Fiehn O, Mullen RT, Hanson AD. Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids. The Plant Cell. 26: 3010-22. PMID 25070638 DOI: 10.1105/tpc.114.126854  0.92
2014 Blekhman R, Perry GH, Shahbaz S, Fiehn O, Clark AG, Gilad Y. Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. Scientific Reports. 4: 5809. PMID 25069065 DOI: 10.1038/srep05809  0.92
2014 Bradbury LM, Ziemak MJ, El Badawi-Sidhu M, Fiehn O, Hanson AD. Plant-driven repurposing of the ancient S-adenosylmethionine repair enzyme homocysteine S-methyltransferase. The Biochemical Journal. 463: 279-86. PMID 25046177 DOI: 10.1042/BJ20140753  0.92
2014 Ogawa T, Furuhashi T, Okazawa A, Nakai R, Nakazawa M, Kind T, Fiehn O, Kanaya S, Arita M, Ohta D. Exploration of polar lipid accumulation profiles in Euglena gracilis using LipidBlast, an MS/MS spectral library constructed in silico. Bioscience, Biotechnology, and Biochemistry. 78: 14-8. PMID 25036478 DOI: 10.1080/09168451.2014.877826  0.92
2014 Wu J, Fiehn O, Armstrong AW. Metabolomic analysis using porcine skin: a pilot study of analytical techniques. Dermatology Online Journal. 20. PMID 24945638  0.92
2014 Cooper-Dehoff RM, Hou W, Weng L, Baillie RA, Beitelshees AL, Gong Y, Shahin MH, Turner ST, Chapman A, Gums JG, Boyle SH, Zhu H, Wikoff WR, Boerwinkle E, Fiehn O, et al. Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose? Circulation. Cardiovascular Genetics. 7: 199-205. PMID 24627569 DOI: 10.1161/CIRCGENETICS.113.000421  0.92
2014 Niehaus TD, Richardson LG, Gidda SK, ElBadawi-Sidhu M, Meissen JK, Mullen RT, Fiehn O, Hanson AD. Plants utilize a highly conserved system for repair of NADH and NADPH hydrates. Plant Physiology. 165: 52-61. PMID 24599492 DOI: 10.1104/pp.114.236539  0.92
2014 Aksenov AA, Pasamontes A, Peirano DJ, Zhao W, Dandekar AM, Fiehn O, Ehsani R, Davis CE. Detection of huanglongbing disease using differential mobility spectrometry Analytical Chemistry. 86: 2481-2488. PMID 24484549 DOI: 10.1021/ac403469y  0.92
2014 Campbell C, Grapov D, Fiehn O, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Gustafson MB, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, Hoppel CL, et al. Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin. Plos One. 9: e84260. PMID 24416208 DOI: 10.1371/journal.pone.0084260  0.92
2014 Yang D, Zhang Y, Barupal DK, Fan X, Gustafson R, Guo R, Fiehn O. Metabolomics of photobiological hydrogen production induced by CCCP in Chlamydomonas reinhardtii International Journal of Hydrogen Energy. 39: 150-158. DOI: 10.1016/j.ijhydene.2013.09.116  0.92
2014 Creek DJ, Dunn WB, Fiehn O, Griffin JL, Hall RD, Lei Z, Mistrik R, Neumann S, Schymanski EL, Sumner LW, Trengove R, Wolfender JL. Metabolite identification: are you sure? And how do your peers gauge your confidence? Metabolomics. 10: 350-353. DOI: 10.1007/s11306-014-0656-8  0.92
2013 Motsinger-Reif AA, Zhu H, Kling MA, Matson W, Sharma S, Fiehn O, Reif DM, Appleby DH, Doraiswamy PM, Trojanowski JQ, Kaddurah-Daouk R, Arnold SE. Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging. Acta Neuropathologica Communications. 1: 28. PMID 24252434 DOI: 10.1186/2051-5960-1-28  0.92
2013 Budczies J, Brockmöller SF, Müller BM, Barupal DK, Richter-Ehrenstein C, Kleine-Tebbe A, Griffin JL, OreÅ¡ič M, Dietel M, Denkert C, Fiehn O. Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: alterations in glutamine and beta-alanine metabolism. Journal of Proteomics. 94: 279-88. PMID 24125731 DOI: 10.1016/j.jprot.2013.10.002  0.4
2013 Perroud B, Jafar-Nejad P, Wikoff WR, Gatchel JR, Wang L, Barupal DK, Crespo-Barreto J, Fiehn O, Zoghbi HY, Kaddurah-Daouk R. Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects. Plos One. 8: e70610. PMID 23936457 DOI: 10.1371/journal.pone.0070610  0.92
2013 Zhu H, Bogdanov MB, Boyle SH, Matson W, Sharma S, Matson S, Churchill E, Fiehn O, Rush JA, Krishnan RR, Pickering E, Delnomdedieu M, Kaddurah-Daouk R. Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway. Plos One. 8: e68283. PMID 23874572 DOI: 10.1371/journal.pone.0068283  0.92
2013 Yerges-Armstrong LM, Ellero-Simatos S, Georgiades A, Zhu H, Lewis JP, Horenstein RB, Beitelshees AL, Dane A, Reijmers T, Hankemeier T, Fiehn O, Shuldiner AR, Kaddurah-Daouk R. Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics. Clinical Pharmacology and Therapeutics. 94: 525-32. PMID 23839601 DOI: 10.1038/clpt.2013.119  0.92
2013 Ibáñez C, Simó C, Barupal DK, Fiehn O, Kivipelto M, Cedazo-Mínguez A, Cifuentes A. A new metabolomic workflow for early detection of Alzheimer's disease. Journal of Chromatography. A. 1302: 65-71. PMID 23827464 DOI: 10.1016/j.chroma.2013.06.005  0.92
2013 Aguer C, Fiehn O, Seifert EL, Bézaire V, Meissen JK, Daniels A, Scott K, Renaud JM, Padilla M, Bickel DR, Dysart M, Adams SH, Harper ME. Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4213-25. PMID 23825224 DOI: 10.1096/fj.13-234302  0.92
2013 Kind T, Liu KH, Lee do Y, DeFelice B, Meissen JK, Fiehn O. LipidBlast in silico tandem mass spectrometry database for lipid identification. Nature Methods. 10: 755-8. PMID 23817071 DOI: 10.1038/nmeth.2551  0.92
2013 Lee do Y, Fiehn O. Metabolomic response of Chlamydomonas reinhardtii to the inhibition of target of rapamycin (TOR) by rapamycin. Journal of Microbiology and Biotechnology. 23: 923-31. PMID 23727803 DOI: 10.4014/jmb.1304.04057  0.92
2013 Sudre D, Gutierrez-Carbonell E, Lattanzio G, Rellán-Álvarez R, Gaymard F, Wohlgemuth G, Fiehn O, Alvarez-Fernández A, Zamarreño AM, Bacaicoa E, Duy D, García-Mina JM, Abadía J, Philippar K, López-Millán AF, et al. Iron-dependent modifications of the flower transcriptome, proteome, metabolome, and hormonal content in an Arabidopsis ferritin mutant. Journal of Experimental Botany. 64: 2665-88. PMID 23682113 DOI: 10.1093/jxb/ert112  0.92
2013 Wikoff WR, Frye RF, Zhu H, Gong Y, Boyle S, Churchill E, Cooper-Dehoff RM, Beitelshees AL, Chapman AB, Fiehn O, Johnson JA, Kaddurah-Daouk R. Pharmacometabolomics reveals racial differences in response to atenolol treatment. Plos One. 8: e57639. PMID 23536766 DOI: 10.1371/journal.pone.0057639  0.92
2013 Davis MC, Fiehn O, Durnford DG. Metabolic acclimation to excess light intensity in Chlamydomonas reinhardtii. Plant, Cell & Environment. 36: 1391-405. PMID 23346954 DOI: 10.1111/pce.12071  0.92
2013 Kaddurah-Daouk R, Bogdanov MB, Wikoff WR, Zhu H, Boyle SH, Churchill E, Wang Z, Rush AJ, Krishnan RR, Pickering E, Delnomdedieu M, Fiehn O. Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo Translational Psychiatry. 3. PMID 23340506 DOI: 10.1038/tp.2012.142  0.92
2013 Kim S, Lee do Y, Wohlgemuth G, Park HS, Fiehn O, Kim KH. Evaluation and optimization of metabolome sample preparation methods for Saccharomyces cerevisiae. Analytical Chemistry. 85: 2169-76. PMID 23289506 DOI: 10.1021/ac302881e  0.92
2013 Pedersen HA, Kudsk P, Fiehn O, Fomsgaard IS. The response of arabidopsis to co-cultivation with clover: Investigating plant-plant interactions with metabolomics Acs Symposium Series. 1141: 189-201. DOI: 10.1021/bk-2013-1141.ch013  0.92
2012 Botanga CJ, Bethke G, Chen Z, Gallie DR, Fiehn O, Glazebrook J. Metabolite profiling of Arabidopsis inoculated with Alternaria brassicicola reveals that ascorbate reduces disease severity. Molecular Plant-Microbe Interactions : Mpmi. 25: 1628-38. PMID 23134520 DOI: 10.1094/MPMI-07-12-0179-R  0.92
2012 Meissen JK, Yuen BT, Kind T, Riggs JW, Barupal DK, Knoepfler PS, Fiehn O. Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism. Plos One. 7: e46770. PMID 23077522 DOI: 10.1371/journal.pone.0046770  0.92
2012 Trupp M, Zhu H, Wikoff WR, Baillie RA, Zeng ZB, Karp PD, Fiehn O, Krauss RM, Kaddurah-Daouk R. Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. Plos One. 7: e38386. PMID 22808006 DOI: 10.1371/journal.pone.0038386  0.92
2012 Lee do Y, Park JJ, Barupal DK, Fiehn O. System response of metabolic networks in Chlamydomonas reinhardtii to total available ammonium. Molecular & Cellular Proteomics : McP. 11: 973-88. PMID 22787274 DOI: 10.1074/mcp.M111.016733  0.92
2012 Ho PP, Kanter JL, Johnson AM, Srinagesh HK, Chang EJ, Purdy TM, van Haren K, Wikoff WR, Kind T, Khademi M, Matloff LY, Narayana S, Hur EM, Lindstrom TM, He Z, ... Fiehn O, et al. Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation. Science Translational Medicine. 4: 137ra73. PMID 22674551 DOI: 10.1126/scitranslmed.3003831  0.92
2012 Quanbeck SM, Brachova L, Campbell AA, Guan X, Perera A, He K, Rhee SY, Bais P, Dickerson JA, Dixon P, Wohlgemuth G, Fiehn O, Barkan L, Lange I, Lange BM, et al. Metabolomics as a Hypothesis-Generating Functional Genomics Tool for the Annotation of Arabidopsis thaliana Genes of "Unknown Function". Frontiers in Plant Science. 3: 15. PMID 22645570 DOI: 10.3389/fpls.2012.00015  0.92
2012 Kind T, Meissen JK, Yang D, Nocito F, Vaniya A, Cheng YS, Vandergheynst JS, Fiehn O. Qualitative analysis of algal secretions with multiple mass spectrometric platforms. Journal of Chromatography. A. 1244: 139-47. PMID 22608776 DOI: 10.1016/j.chroma.2012.04.074  0.92
2012 Barupal DK, Haldiya PK, Wohlgemuth G, Kind T, Kothari SL, Pinkerton KE, Fiehn O. MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity. Bmc Bioinformatics. 13: 99. PMID 22591066 DOI: 10.1186/1471-2105-13-99  0.92
2012 Song IS, Lee do Y, Shin MH, Kim H, Ahn YG, Park I, Kim KH, Kind T, Shin JG, Fiehn O, Liu KH. Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. Plos One. 7: e36637. PMID 22590580 DOI: 10.1371/journal.pone.0036637  0.92
2012 Wilmarth PA, Short KK, Fiehn O, Lutsenko S, David LL, Burkhead JL. A systems approach implicates nuclear receptor targeting in the Atp7b -/- mouse model of Wilson's disease Metallomics. 4: 660-668. PMID 22565294 DOI: 10.1039/c2mt20017a  0.92
2012 Denkert C, Bucher E, Hilvo M, Salek R, Oreši? M, Griffin J, Brockmöller S, Klauschen F, Loibl S, Barupal DK, Budczies J, Iljin K, Nekljudova V, Fiehn O. Metabolomics of human breast cancer: new approaches for tumor typing and biomarker discovery. Genome Medicine. 4: 37. PMID 22546809 DOI: 10.1186/gm336  0.4
2012 Meyer RC, Witucka-Wall H, Becher M, Blacha A, Boudichevskaia A, Dörmann P, Fiehn O, Friedel S, von Korff M, Lisec J, Melzer M, Repsilber D, Schmidt R, Scholz M, Selbig J, et al. Heterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids. The Plant Journal : For Cell and Molecular Biology. 71: 669-83. PMID 22487254 DOI: 10.1111/j.1365-313X.2012.05021.x  0.92
2012 Eckert AJ, Wegrzyn JL, Cumbie WP, Goldfarb B, Huber DA, Tolstikov V, Fiehn O, Neale DB. Association genetics of the loblolly pine (Pinus taeda, Pinaceae) metabolome. The New Phytologist. 193: 890-902. PMID 22129444 DOI: 10.1111/j.1469-8137.2011.03976.x  0.92
2012 Tushingham S, Ardura D, Eerkens JW, Palazoglu M, Shahbaz S, Fiehn O. Hunter-gatherer tobacco smoking: earliest evidence from the Pacific Northwest Coast of North America Journal of Archaeological Science. DOI: 10.1016/j.jas.2012.09.019  0.92
2012 Fiehn O. The 27th asilomar conference on mass spectrometry, metabolomics, October 2011 Journal of the American Society For Mass Spectrometry. 23: 1000-1002. DOI: 10.1007/s13361-012-0364-4  0.92
2011 Rellán-Álvarez R, El-Jendoubi H, Wohlgemuth G, Abadía A, Fiehn O, Abadía J, Alvarez-Fernández A. Metabolite profile changes in xylem sap and leaf extracts of strategy I plants in response to iron deficiency and resupply. Frontiers in Plant Science. 2: 66. PMID 22645546 DOI: 10.3389/fpls.2011.00066  0.92
2011 Brosnan RJ, Steffey EP, Escobar A, Palazoglu M, Fiehn O. Anesthetic induction with guaifenesin and propofol in adult horses. American Journal of Veterinary Research. 72: 1569-75. PMID 22126682 DOI: 10.2460/ajvr.72.12.1569  0.92
2011 Hirahatake KM, Meissen JK, Fiehn O, Adams SH. Comparative effects of fructose and glucose on lipogenic gene expression and intermediary metabolism in HepG2 liver cells. Plos One. 6: e26583. PMID 22096489 DOI: 10.1371/journal.pone.0026583  0.92
2011 Skogerson K, Wohlgemuth G, Barupal DK, Fiehn O. The volatile compound BinBase mass spectral database. Bmc Bioinformatics. 12: 321. PMID 21816034 DOI: 10.1186/1471-2105-12-321  0.92
2011 Kumari S, Stevens D, Kind T, Denkert C, Fiehn O. Applying in-silico retention index and mass spectra matching for identification of unknown metabolites in accurate mass GC-TOF mass spectrometry. Analytical Chemistry. 83: 5895-902. PMID 21678983 DOI: 10.1021/ac2006137  0.92
2011 Fiehn O, Barupal DK, Kind T. Extending biochemical databases by metabolomic surveys. The Journal of Biological Chemistry. 286: 23637-43. PMID 21566124 DOI: 10.1074/jbc.R110.173617  0.92
2011 Wu D, Nishimura N, Kuo V, Fiehn O, Shahbaz S, Van Winkle L, Matsumura F, Vogel CF. Activation of aryl hydrocarbon receptor induces vascular inflammation and promotes atherosclerosis in apolipoprotein E-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1260-7. PMID 21441140 DOI: 10.1161/ATVBAHA.110.220202  0.92
2011 Robertson DG, Ruepp SU, Stryker SA, Hnatyshyn SY, Shipkova PA, Aranibar N, Mcnaney CA, Fiehn O, Reily MD. Metabolomic and transcriptomic changes induced by overnight (16 h) fasting in male and female Sprague-Dawley rats. Chemical Research in Toxicology. 24: 481-7. PMID 21381695 DOI: 10.1021/tx200074f  0.92
2011 Buckendahl AC, Budczies J, Fiehn O, Darb-Esfahani S, Kind T, Noske A, Weichert W, Sehouli J, Braicu E, Dietel M, Denkert C. Prognostic impact of AMP-activated protein kinase expression in ovarian carcinoma: correlation of protein expression and GC/TOF-MS-based metabolomics. Oncology Reports. 25: 1005-12. PMID 21271224 DOI: 10.3892/or.2011.1162  0.92
2011 Reichenbach SE, Tian X, Tao Q, Ledford EB, Wu Z, Fiehn O. Informatics for cross-sample analysis with comprehensive two-dimensional gas chromatography and high-resolution mass spectrometry (GCxGC-HRMS). Talanta. 83: 1279-88. PMID 21215864 DOI: 10.1016/j.talanta.2010.09.057  0.92
2011 Ji Y, Hebbring S, Zhu H, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Zeng Z, Schaid D, Mrazek DA, Kaddurah-Daouk R, Weinshilboum RM. Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics. Clinical Pharmacology and Therapeutics. 89: 97-104. PMID 21107318 DOI: 10.1038/clpt.2010.250  0.92
2011 Fiehn O, Barupal DK, Kind T. Extending biochemical databases by metabolomic surveys (Journal of Biological Chemistry (2011) 286, (23637-23643)) Journal of Biological Chemistry. 286: 30244. DOI: 10.1074/jbc.A110.173617  0.92
2011 Fiehn O, Kind T, Barupal DK. Data Processing, Metabolomic Databases and Pathway Analysis Annual Plant Reviews Volume 43: Biology of Plant Metabolomics. 43: 367-406. DOI: 10.1002/9781444339956.ch12  0.92
2010 Kind T, Fiehn O. Advances in structure elucidation of small molecules using mass spectrometry. Bioanalytical Reviews. 2: 23-60. PMID 21289855 DOI: 10.1007/s12566-010-0015-9  0.92
2010 Fiehn O, Garvey WT, Newman JW, Lok KH, Hoppel CL, Adams SH. Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. Plos One. 5: e15234. PMID 21170321 DOI: 10.1371/journal.pone.0015234  0.92
2010 Luengwilai K, Fiehn OE, Beckles DM. Comparison of leaf and fruit metabolism in two tomato (Solanum lycopersicum L.) genotypes varying in total soluble solids. Journal of Agricultural and Food Chemistry. 58: 11790-800. PMID 21033662 DOI: 10.1021/jf102562n  0.92
2010 Wohlgemuth G, Haldiya PK, Willighagen E, Kind T, Fiehn O. The Chemical Translation Service--a web-based tool to improve standardization of metabolomic reports. Bioinformatics (Oxford, England). 26: 2647-8. PMID 20829444 DOI: 10.1093/bioinformatics/btq476  0.92
2010 Sana TR, Fischer S, Wohlgemuth G, Katrekar A, Jung KH, Ronald PC, Fiehn O. Metabolomic and transcriptomic analysis of the rice response to the bacterial blight pathogen Xanthomonas oryzae pv. oryzae. Metabolomics : Official Journal of the Metabolomic Society. 6: 451-465. PMID 20676379 DOI: 10.1007/s11306-010-0218-7  0.92
2010 Shin MH, Lee do Y, Liu KH, Fiehn O, Kim KH. Evaluation of sampling and extraction methodologies for the global metabolic profiling of Saccharophagus degradans. Analytical Chemistry. 82: 6660-6. PMID 20669998 DOI: 10.1021/ac1012656  0.92
2010 Zhang B, Tolstikov V, Turnbull C, Hicks LM, Fiehn O. Divergent metabolome and proteome suggest functional independence of dual phloem transport systems in cucurbits. Proceedings of the National Academy of Sciences of the United States of America. 107: 13532-7. PMID 20566864 DOI: 10.1073/pnas.0910558107  0.92
2010 Rellán-Alvarez R, Andaluz S, Rodríguez-Celma J, Wohlgemuth G, Zocchi G, Alvarez-Fernández A, Fiehn O, López-Millán AF, Abadía J. Changes in the proteomic and metabolic profiles of Beta vulgaris root tips in response to iron deficiency and resupply. Bmc Plant Biology. 10: 120. PMID 20565974 DOI: 10.1186/1471-2229-10-120  0.92
2010 Barupal DK, Kind T, Kothari SL, Lee do Y, Fiehn O. Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. Bmc Biotechnology. 10: 40. PMID 20492649 DOI: 10.1186/1472-6750-10-40  0.92
2010 Dandekar AM, Martinelli F, Davis CE, Bhushan A, Zhao W, Fiehn O, Skogerson K, Wohlgemuth G, D'Souza R, Roy S, Reagan RL, Lin D, Cary R, Pardington P, Gupta G. Analysis of early host responses for asymptomatic disease detection and management of specialty crops. Critical Reviews in Immunology. 30: 277-89. PMID 20370635  0.92
2010 Seifert EL, Fiehn O, Bezaire V, Bickel DR, Wohlgemuth G, Adams SH, Harper ME. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. Plos One. 5: e9834. PMID 20352092 DOI: 10.1371/journal.pone.0009834  0.92
2010 Abate S, Ahn YG, Kind T, Cataldi TR, Fiehn O. Determination of elemental compositions by gas chromatography/time-of-flight mass spectrometry using chemical and electron ionization. Rapid Communications in Mass Spectrometry : Rcm. 24: 1172-80. PMID 20301109 DOI: 10.1002/rcm.4482  0.92
2010 Shin MH, Lee do Y, Wohlgemuth G, Choi IG, Fiehn O, Kim KH. Global metabolite profiling of agarose degradation by Saccharophagus degradans 2-40. New Biotechnology. 27: 156-68. PMID 20215059 DOI: 10.1016/j.nbt.2010.02.023  0.92
2010 Skogerson K, Harrigan GG, Reynolds TL, Halls SC, Ruebelt M, Iandolino A, Pandravada A, Glenn KC, Fiehn O. Impact of genetics and environment on the metabolite composition of maize grain. Journal of Agricultural and Food Chemistry. 58: 3600-10. PMID 20158212 DOI: 10.1021/jf903705y  0.92
2010 Bais P, Moon SM, He K, Leitao R, Dreher K, Walk T, Sucaet Y, Barkan L, Wohlgemuth G, Roth MR, Wurtele ES, Dixon P, Fiehn O, Lange BM, Shulaev V, et al. PlantMetabolomics.org: a web portal for plant metabolomics experiments. Plant Physiology. 152: 1807-16. PMID 20147492 DOI: 10.1104/pp.109.151027  0.92
2010 Taylor SL, Ganti S, Bukanov NO, Chapman A, Fiehn O, Osier M, Kim K, Weiss RH. A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease. American Journal of Physiology. Renal Physiology. 298: F909-22. PMID 20130118 DOI: 10.1152/ajprenal.00722.2009  0.92
2010 Burke G, Fiehn O, Moran N. Effects of facultative symbionts and heat stress on the metabolome of pea aphids Isme Journal. 4: 242-252. PMID 19907504 DOI: 10.1038/ismej.2009.114  0.92
2010 Shin MH, Lee DY, Skogerson K, Wohlgemuth G, Choi IG, Fiehn O, Kim KH. Global metabolic profiling of plant cell wall polysaccharide degradation by Saccharophagus degradans. Biotechnology and Bioengineering. 105: 477-88. PMID 19806675 DOI: 10.1002/bit.22557  0.92
2010 Budczies J, Denkert C, Müller BM, Brockmöller SF, Dietel M, Griffin JL, Oresic M, Fiehn O. METAtarget-Extracting key enzymes of metabolic regulation from high-throughput metabolomics data using KEGG REACTION information Gcb 2010 - German Conference On Bioinformatics 2010. 103-112.  0.92
2009 Kind T, Fiehn O. What are the obstacles for an integrated system for comprehensive interpretation of cross-platform metabolic profile data? Bioanalysis. 1: 1511-4. PMID 21083097 DOI: 10.4155/bio.09.141  0.92
2009 Kind T, Leamy T, Leary JA, Fiehn O. Software platform virtualization in chemistry research and university teaching. Journal of Cheminformatics. 1: 18. PMID 20150997 DOI: 10.1186/1758-2946-1-18  0.92
2009 Scalbert A, Brennan L, Fiehn O, Hankemeier T, Kristal BS, van Ommen B, Pujos-Guillot E, Verheij E, Wishart D, Wopereis S. Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research. Metabolomics : Official Journal of the Metabolomic Society. 5: 435-458. PMID 20046865 DOI: 10.1007/s11306-009-0168-0  0.92
2009 Kind T, Wohlgemuth G, Lee DY, Lu Y, Palazoglu M, Shahbaz S, Fiehn O. FiehnLib: mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry. Analytical Chemistry. 81: 10038-48. PMID 19928838 DOI: 10.1021/ac9019522  0.92
2009 Hartman AL, Lough DM, Barupal DK, Fiehn O, Fishbein T, Zasloff M, Eisen JA. Human gut microbiome adopts an alternative state following small bowel transplantation. Proceedings of the National Academy of Sciences of the United States of America. 106: 17187-92. PMID 19805153 DOI: 10.1073/pnas.0904847106  0.92
2009 Martinelli F, Uratsu SL, Reagan RL, Chen Y, Tricoli D, Fiehn O, Rocke DM, Gasser CS, Dandekar AM. Gene regulation in parthenocarpic tomato fruit. Journal of Experimental Botany. 60: 3873-90. PMID 19700496 DOI: 10.1093/jxb/erp227  0.92
2009 Skogerson K, Runnebaum R, Wohlgemuth G, de Ropp J, Heymann H, Fiehn O. Comparison of gas chromatography-coupled time-of-flight mass spectrometry and 1H nuclear magnetic resonance spectroscopy metabolite identification in white wines from a sensory study investigating wine body. Journal of Agricultural and Food Chemistry. 57: 6899-907. PMID 19588931 DOI: 10.1021/jf9019322  0.92
2009 Kind T, Scholz M, Fiehn O. How Large Is the Metabolome? A Critical Analysis of Data Exchange Practices in Chemistry Plos One. 4. PMID 19415114 DOI: 10.1371/journal.pone.0005440  0.92
2008 Ulu A, Davis BB, Tsai HJ, Kim IH, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH. Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model. Journal of Cardiovascular Pharmacology. 52: 314-23. PMID 18791465 DOI: 10.1097/FJC.0b013e318185fa3c  0.92
2008 Lee DY, Fiehn O. High quality metabolomic data for Chlamydomonas reinhardtii. Plant Methods. 4: 7. PMID 18442406 DOI: 10.1186/1746-4811-4-7  0.92
2008 Ikegami T, Horie K, Saad N, Hosoya K, Fiehn O, Tanaka N. Highly efficient analysis of underivatized carbohydrates using monolithic-silica-based capillary hydrophilic interaction (HILIC) HPLC Analytical and Bioanalytical Chemistry. 391: 2533-2542. PMID 18415087 DOI: 10.1007/s00216-008-2060-6  0.92
2008 Fiehn O, Wohlgemuth G, Scholz M, Kind T, Lee DY, Lu Y, Moon S, Nikolau B. Quality control for plant metabolomics: reporting MSI-compliant studies. The Plant Journal : For Cell and Molecular Biology. 53: 691-704. PMID 18269577 DOI: 10.1111/j.1365-313X.2007.03387.x  0.92
2008 Lisec J, Meyer RC, Steinfath M, Redestig H, Becher M, Witucka-Wall H, Fiehn O, Törjék O, Selbig J, Altmann T, Willmitzer L. Identification of metabolic and biomass QTL in Arabidopsis thaliana in a parallel analysis of RIL and IL populations. The Plant Journal : For Cell and Molecular Biology. 53: 960-72. PMID 18047556 DOI: 10.1111/j.1365-313X.2007.03383.x  0.92
2008 Fiehn O. Extending the breadth of metabolite profiling by gas chromatography coupled to mass spectrometry Trac - Trends in Analytical Chemistry. 27: 261-269. DOI: 10.1016/j.trac.2008.01.007  0.92
2008 Kind T, Fiehn O. Hardware and software challenges for the near future: Structure elucidation concepts via hyphenated chromatographic techniques Lcgc North America. 26: 176-187.  0.92
2007 Scholz M, Fiehn O. Setup X-a public study design database for metabolomic projects Pacific Symposium On Biocomputing 2007, Psb 2007. 169-180. PMID 17990490  0.92
2007 Horie K, Ikegami T, Hosoya K, Saad N, Fiehn O, Tanaka N. Highly efficient monolithic silica capillary columns modified with poly(acrylic acid) for hydrophilic interaction chromatography Journal of Chromatography A. 1164: 198-205. PMID 17689542 DOI: 10.1016/j.chroma.2007.07.012  0.92
2007 Kose F, Budczies J, Holschneider M, Fiehn O. Robust detection and verification of linear relationships to generate metabolic networks using estimates of technical errors Bmc Bioinformatics. 8. PMID 17517139 DOI: 10.1186/1471-2105-8-162  0.92
2007 Horie K, Kimura H, Ikegami T, Iwatsuka A, Saad N, Fiehn O, Tanaka N. Calculating optimal modulation periods to maximize the peak capacity in two-dimensional HPLC Analytical Chemistry. 79: 3764-3770. PMID 17437330 DOI: 10.1021/ac062002t  0.92
2007 Kind T, Fiehn O. Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry Bmc Bioinformatics. 8. PMID 17389044 DOI: 10.1186/1471-2105-8-105  0.92
2007 Meyer RC, Steinfath M, Lisec J, Becher M, Witucka-Wall H, Törjék O, Fiehn O, Eckardt A, Willmitzer L, Selbig J, Altmann T. The metabolic signature related to high plant growth rate in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 104: 4759-64. PMID 17360597 DOI: 10.1073/pnas.0609709104  0.92
2007 Kind T, Tolstikov V, Fiehn O, Weiss RH. A comprehensive urinary metabolomic approach for identifying kidney cancerr Analytical Biochemistry. 363: 185-195. PMID 17316536 DOI: 10.1016/j.ab.2007.01.028  0.92
2007 Huster D, Purnat TD, Burkhead JL, Ralle M, Fiehn O, Stuckert F, Olson NE, Teupser D, Lutsenko S. High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease. The Journal of Biological Chemistry. 282: 8343-55. PMID 17205981 DOI: 10.1074/jbc.M607496200  0.92
2007 Frey IM, Rubio-Aliaga I, Siewert A, Sailer D, Drobyshev A, Beckers J, De Angelis MH, Aubert J, Hen AB, Fiehn O, Eichinger HM, Daniel H. Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice Physiological Genomics. 28: 301-310. PMID 17077276 DOI: 10.1152/physiolgenomics.00193.2006  0.92
2007 Tolstikov VV, Fiehn O, Tanaka N. Application of liquid chromatography-mass spectrometry analysis in metabolomics: reversed-phase monolithic capillary chromatography and hydrophilic chromatography coupled to electrospray ionization-mass spectrometry Methods in Molecular Biology (Clifton, N.J.). 358: 141-155. PMID 17035685  0.92
2007 Fiehn O, Kind T. Metabolite profiling in blood plasma Methods in Molecular Biology (Clifton, N.J.). 358: 3-17. PMID 17035677  0.92
2007 Fiehn O. Cellular Metabolimics: The Quest for Pathway Structure The Handbook of Metabonomics and Metabolomics. 35-54. DOI: 10.1016/B978-044452841-4/50003-5  0.92
2007 Sansone SA, Schober D, Atherton HJ, Fiehn O, Jenkins H, Rocca-Serra P, Rubtsov DV, Spasic I, Soldatova L, Taylor C, Tseng A, Viant MR. Metabolomics standards initiative: Ontology working group work in progress Metabolomics. 3: 249-256. DOI: 10.1007/s11306-007-0069-z  0.92
2007 Fiehn O, Sumner LW, Rhee SY, Ward J, Dickerson J, Lange BM, Lane G, Roessner U, Last R, Nikolau B. Minimum reporting standards for plant biology context information in metabolomic studies Metabolomics. 3: 195-201. DOI: 10.1007/s11306-007-0068-0  0.92
2007 Fiehn O. Study of Metabolic Control in Plants by Metabolomics Annual Plant Reviews. 22: 60-84. DOI: 10.1002/9780470988640.ch3  0.92
2006 Perroud B, Lee J, Valkova N, Dhirapong A, Lin PY, Fiehn O, Kültz D, Weiss RH. Pathway analysis of kidney cancer using proteomics and metabolic profiling Molecular Cancer. 5. PMID 17123452 DOI: 10.1186/1476-4598-5-64  0.92
2006 Dixon RA, Gang DR, Charlton AJ, Fiehn O, Kuiper HA, Reynolds TL, Tjeerdema RS, Jeffery EH, German JB, Ridley WP, Seiber JN. Applications of metabolomics in agriculture. Journal of Agricultural and Food Chemistry. 54: 8984-94. PMID 17117782 DOI: 10.1021/jf061218t  0.92
2006 Denkert C, Budczies J, Kind T, Weichert W, Tablack P, Sehouli J, Niesporek S, Könsgen D, Dietel M, Fiehn O. Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors Cancer Research. 66: 10795-10804. PMID 17108116 DOI: 10.1158/0008-5472.CAN-06-0755  0.92
2006 Fiehn O, Kristal B, Van Ommen B, Sumner LW, Sansone SA, Taylor C, Hardy N, Kaddurah-Daouk R. Establishing reporting standards for metabolomic and metabonomic studies: A call for participation Omics a Journal of Integrative Biology. 10: 158-163. PMID 16901221 DOI: 10.1089/omi.2006.10.158  0.92
2006 Hannah MA, Wiese D, Freund S, Fiehn O, Heyer AG, Hincha DK. Natural genetic variation of freezing tolerance in Arabidopsis. Plant Physiology. 142: 98-112. PMID 16844837 DOI: 10.1104/pp.106.081141  0.92
2006 Castle AL, Fiehn O, Kaddurah-Daouk R, Lindon JC. Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results Briefings in Bioinformatics. 7: 159-165. PMID 16772263 DOI: 10.1093/bib/bbl008  0.92
2006 Fiehn O. Metabolite profiling in Arabidopsis Methods in Molecular Biology (Clifton, N.J.). 323: 439-447. PMID 16739598  0.92
2006 Kind T, Fiehn O. Metabolomic database annotations via query of elemental compositions: Mass accuracy is insufficient even at less than 1 ppm Bmc Bioinformatics. 7. PMID 16646969 DOI: 10.1186/1471-2105-7-234  0.92
2005 Tagashira N, Plader W, Filipecki M, Yin Z, Wiśniewska A, Gaj P, Szwacka M, Fiehn O, Hoshi Y, Kondo K, Malepszy S. The metabolic profiles of transgenic cucumber lines vary with different chromosomal locations of the transgene Cellular and Molecular Biology Letters. 10: 697-710. PMID 16341278  0.92
2005 Bölling C, Fiehn O. Metabolite profiling of Chlamydomonas reinhardtii under nutrient deprivation Plant Physiology. 139: 1995-2005. PMID 16306140 DOI: 10.1104/pp.105.071589  0.92
2005 Schad M, Mungur R, Fiehn O, Kehr J. Metabolic profiling of laser microdissected vascular bundles of Arabidopsis thaliana. Plant Methods. 1: 2. PMID 16270917 DOI: 10.1186/1746-4811-1-2  0.92
2005 Catchpole GS, Beckmann M, Enot DP, Mondhe M, Zywicki B, Taylor J, Hardy N, Smith A, King RD, Kell DB, Fiehn O, Draper J. Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops. Proceedings of the National Academy of Sciences of the United States of America. 102: 14458-62. PMID 16186495 DOI: 10.1073/pnas.0503955102  0.92
2005 Shellie RA, Welthagen W, Zrostliková J, Spranger J, Ristow M, Fiehn O, Zimmermann R. Statistical methods for comparing comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry results: Metabolomic analysis of mouse tissue extracts Journal of Chromatography A. 1086: 83-90. PMID 16130658 DOI: 10.1016/j.chroma.2005.05.088  0.92
2005 Nikiforova VJ, Kopka J, Tolstikov V, Fiehn O, Hopkins L, Hawkesford MJ, Hesse H, Hoefgen R. Systems rebalancing of metabolism in response to sulfur deprivation, as revealed by metabolome analysis of arabidopsis plants Plant Physiology. 138: 304-318. PMID 15834012 DOI: 10.1104/pp.104.053793  0.92
2005 Zywicki B, Catchpole G, Draper J, Fiehn O. Comparison of rapid liquid chromatography-electrospray ionization-tandem mass spectrometry methods for determination of glycoalkaloids in transgenic field-grown potatoes Analytical Biochemistry. 336: 178-186. PMID 15620882 DOI: 10.1016/j.ab.2004.10.013  0.92
2005 Welthagen W, Shellie RA, Spranger J, Ristow M, Zimmermann R, Fiehn O. Comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC × GC-TOF) for high resolution metabolomics: Biomarker discovery on spleen tissue extracts of obese NZO compared to lean C57BL/6 mice Metabolomics. 1: 65-73. DOI: 10.1007/s11306-005-1108-2  0.92
2005 Ikegami T, Kobayashi H, Kimura H, Tolstikov VV, Fiehn O, Tanaka N. High-performance liquid chromatography for metabolomics: High-efficiency separations utilizing monolithic silica columns Metabolomics: the Frontier of Systems Biology. 107-126. DOI: 10.1007/4-431-28055-3_8  0.92
2005 Fiehn O, Wohlgemuth G, Scholz M. Setup and annotation of metabolomic experiments by integrating biological and mass spectrometric metadata Lecture Notes in Bioinformatics (Subseries of Lecture Notes in Computer Science). 3615: 224-239.  0.92
2004 Cook D, Fowler S, Fiehn O, Thomashow MF. A prominent role for the CBF cold response pathway in configuring the low-temperature metabolome of Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America. 101: 15243-8. PMID 15383661 DOI: 10.1073/pnas.0406069101  0.92
2004 Bino RJ, Hall RD, Fiehn O, Kopka J, Saito K, Draper J, Nikolau BJ, Mendes P, Roessner-Tunali U, Beale MH, Trethewey RN, Lange BM, Wurtele ES, Sumner LW. Potential of metabolomics as a functional genomics tool. Trends in Plant Science. 9: 418-25. PMID 15337491 DOI: 10.1016/j.tplants.2004.07.004  0.92
2004 Weckwerth W, Loureiro ME, Wenzel K, Fiehn O. Differential metabolic networks unravel the effects of silent plant phenotypes Proceedings of the National Academy of Sciences of the United States of America. 101: 7809-7814. PMID 15136733 DOI: 10.1073/pnas.0303415101  0.92
2004 Scholz M, Gatzek S, Sterling A, Fiehn O, Selbig J. Metabolite fingerprinting: Detecting biological features by independent component analysis Bioinformatics. 20: 2447-2454. PMID 15087312 DOI: 10.1093/bioinformatics/bth270  0.92
2004 Wienkoop S, Glinski M, Tanaka N, Tolstikov V, Fiehn O, Weckwerth W. Linking protein fractionation with multidimensional monolithic reversed-phase peptide chromatography/mass spectrometry enhances protein identification from complex mixtures even in the presence of abundant proteins Rapid Communications in Mass Spectrometry. 18: 643-650. PMID 15052571  0.92
2004 Weckwerth W, Wenzel K, Fiehn O. Process for the integrated extraction, identification and quantification of metabolites, proteins and RNA to reveal their co-regulation in biochemical networks Proteomics. 4: 78-83. PMID 14730673 DOI: 10.1002/pmic.200200500  0.92
2003 Steuer R, Kurths J, Fiehn O, Weckwerth W. Interpreting correlations in metabolomic networks Biochemical Society Transactions. 31: 1476-1478. PMID 14641093  0.92
2003 Tolstikov VV, Lommen A, Nakanishi K, Tanaka N, Fiehn O. Monolithic Silica-Based Capillary Reversed-Phase Liquid Chromatography/Electrospray Mass Spectrometry for Plant Metabolomics Analytical Chemistry. 75: 6737-6740. PMID 14640754 DOI: 10.1021/ac034716z  0.92
2003 Steuer R, Kurths J, Fiehn O, Weckwerth W. Observing and interpreting correlations in metabolomic networks Bioinformatics. 19: 1019-1026. PMID 12761066 DOI: 10.1093/bioinformatics/btg120  0.92
2003 Fiehn O. Metabolic networks of Cucurbita maxima phloem Phytochemistry. 62: 875-886. PMID 12590115 DOI: 10.1016/S0031-9422(02)00715-X  0.92
2003 Fiehn O, Weckwerth W. Deciphering metabolic networks European Journal of Biochemistry. 270: 579-588. PMID 12581198 DOI: 10.1046/j.1432-1033.2003.03427.x  0.92
2002 Taylor J, King RD, Altmann T, Fiehn O. Application of metabolomics to plant genotype discrimination using statistics and machine learning. Bioinformatics (Oxford, England). 18: S241-8. PMID 12386008  0.92
2002 Hall R, Beale M, Fiehn O, Hardy N, Sumner L, Bino R. Plant metabolomics: The missing link in functional genomics strategies Plant Cell. 14: 1437-1440. PMID 12119365 DOI: 10.1105/tpc.140720  0.92
2002 Weckwerth W, Fiehn O. Can we discover novel pathways using metabolomic analysis? Current Opinion in Biotechnology. 13: 156-160. PMID 11950569 DOI: 10.1016/S0958-1669(02)00299-9  0.92
2002 Fiehn O. Metabolomics - The link between genotypes and phenotypes Plant Molecular Biology. 48: 155-171. PMID 11860207 DOI: 10.1023/A:1013713905833  0.92
2002 Tolstikov VV, Fiehn O. Analysis of highly polar compounds of plant origin: Combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry Analytical Biochemistry. 301: 298-307. PMID 11814300 DOI: 10.1006/abio.2001.5513  0.92
2002 Kose F, Weckwerth W, Linke T, Fiehn O. Visualizing plant metabolomic correlation networks using clique-metabolite matrices Bioinformatics. 17: 1198-1208. PMID 11751228  0.92
2002 Fiehn O, Spranger J. Can metabolomics be used for assessing nutritive-dependent human diseases? Phytochemistry Reviews. 1: 223-230. DOI: 10.1023/A:1022567619029  0.92
2002 Tolstikov V, Costisella B, Weckwerth W, Zhang B, Fiehn O. Accurate mass QTOF and MS∧n Ion trap measurements require additional NMR data for plant metabolites de-novo identification Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 417-418.  0.92
2001 Szopa J, Wilczyński G, Fiehn O, Wenczel A, Willmitzer L. Identification and quantification of catecholamines in potato plants (Solanum tuberosum) by GC-MS Phytochemistry. 58: 315-320. PMID 11551557 DOI: 10.1016/S0031-9422(01)00232-1  0.92
2001 Vogel G, Fiehn O, Jean-Richard-Dit-Bressel L, Boller T, Wiemken A, Aeschbacher RA, Wingler A. Trehalose metabolism in Arabidopsis: Occurrence of trehalose and molecular cloning and characterization of trehalose-6-phosphate synthase homologues Journal of Experimental Botany. 52: 1817-1826. PMID 11520870  0.92
2001 Fiehn O, Kloska S, Altmann T. Integrated studies on plant biology using multiparallel techniques Current Opinion in Biotechnology. 12: 82-86. PMID 11167078 DOI: 10.1016/S0958-1669(00)00165-8  0.92
2001 Roessner U, Luedemann A, Brust D, Fiehn O, Linke T, Willmitzer L, Fernie AR. Metabolic profiling allows comprehensive phenotyping of genetically or environmentally modified plant systems Plant Cell. 13: 11-29. PMID 11158526 DOI: 10.1105/tpc.13.1.11  0.92
2001 Fiehn O. Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks Comparative and Functional Genomics. 2: 155-168. DOI: 10.1002/cfg.82  0.92
2000 Fiehn O, Kopka J, Dörmann P, Altmann T, Trethewey RN, Willmitzer L. Metabolite profiling for plant functional genomics Nature Biotechnology. 18: 1157-1161. PMID 11062433 DOI: 10.1038/81137  0.92
2000 Fiehn O, Kopka J, Trethewey RN, Willmitzer L. Identification of uncommon plant metabolites based on calculation of elemental compositions using gas chromatography and quadrupole mass spectrometry Analytical Chemistry. 72: 3573-3580. PMID 10952545  0.92
2000 Goodlett DR, Bruce JE, Anderson GA, Rist B, Pasa-Tolic L, Fiehn O, Smith RD, Aebersold R. Protein identification with a single accurate mass of a cysteine- containing peptide and constrained database searching Analytical Chemistry. 72: 1112-1118. PMID 10740847 DOI: 10.1021/ac9913210  0.92
1999 Reemtsma T, Fiehn O, Jekel M. A modified method for the analysis of organics in industrial wastewater as directed by their toxicity to Vibrio fischeri Fresenius' Journal of Analytical Chemistry. 363: 771-776.  0.92
1998 Fiehn O, Wegener G, Jochimsen J, Jekel M. Analysis of the ozonation of 2-mercaptobenzothiazole in water and tannery wastewater using sum parameters, liquid- and gas chromatography and capillary electrophoresis Water Research. 32: 1075-1084. DOI: 10.1016/S0043-1354(97)00332-1  0.92
1998 Fiehn O, Wegener G, Jekel M. Capillary electrophoretic analysis of organic anions in tannery wastewater including high contents of chloride and sulfate International Journal of Environmental Analytical Chemistry. 69: 257-271.  0.92
1997 Fiehn O, Jekel M. Analysis of phenolic compounds in industrial wastewater with high-performance liquid chromatography and post-column reaction detection Journal of Chromatography A. 769: 189-200. DOI: 10.1016/S0021-9673(97)00057-5  0.92
1997 Fiehn O, Vigelahn L, Kalnowski G, Reemtsma T, Jekel M. Toxicity-directed fractionation of tannery wastewater using solid-phase extraction and luminescence inhibition in microtiter plates Acta Hydrochimica Et Hydrobiologica. 25: 11-16.  0.92
1996 Fiehn O, Jekel M. Comparison of Sorbents Using Semipolar to Highly Hydrophilic Compounds for a Sequential Solid-Phase Extraction Procedure of Industrial Wastewaters Analytical Chemistry. 68: 3083-3089.  0.92
1995 Reemtsma T, Fiehn O, Kalnowski G, Jekel M. Microbial transformations and biological effects of fungicide- derived benzothiazoles determined in industrial wastewater Environmental Science &Amp; Technology. 29: 478-485.  0.92
1994 Fiehn O, Reemtsma T, Jekel M. Extraction and analysis of various benzothiazoles from industrial wastewater Analytica Chimica Acta. 295: 297-305. DOI: 10.1016/0003-2670(94)80235-1  0.92
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