| Year |
Citation |
Score |
| 2023 |
Reeves MQ, Balmain A. Mutations, Bottlenecks, and Clonal Sweeps: How Environmental Carcinogens and Genomic Changes Shape Clonal Evolution during Tumor Progression. Cold Spring Harbor Perspectives in Medicine. PMID 38052482 DOI: 10.1101/cshperspect.a041388 |
0.301 |
|
| 2020 |
Balmain A. The critical roles of somatic mutations and environmental tumor-promoting agents in cancer risk. Nature Genetics. 52: 1139-1143. PMID 33106632 DOI: 10.1038/s41588-020-00727-5 |
0.317 |
|
| 2020 |
Ku AA, Hu HM, Zhao X, Shah KN, Kongara S, Wu D, McCormick F, Balmain A, Bandyopadhyay S. Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibility. Nature Communications. 11: 2375. PMID 32398776 DOI: 10.1038/S41467-020-16078-Y |
0.352 |
|
| 2020 |
Rose Li Y, Halliwill KD, Adams CJ, Iyer V, Riva L, Mamunur R, Jen KY, Del Rosario R, Fredlund E, Hirst G, Alexandrov LB, Adams D, Balmain A. Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice. Nature Communications. 11: 394. PMID 31959748 DOI: 10.1038/S41467-019-14261-4 |
0.33 |
|
| 2020 |
Mahaffety JP, Amendola CR, Chen W, Kimmelman A, Balmain A, Philips MR. Abstract A13: KRAS4A directly regulates hexokinase 1 Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Ras18-A13 |
0.353 |
|
| 2019 |
Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, ... Balmain A, et al. KRAS4A directly regulates hexokinase 1. Nature. PMID 31827279 DOI: 10.1038/S41586-019-1832-9 |
0.352 |
|
| 2019 |
Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, ... ... Balmain A, et al. α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas. Journal For Immunotherapy of Cancer. 7: 62. PMID 30832732 DOI: 10.1186/S40425-018-0493-9 |
0.344 |
|
| 2019 |
Li YR, Halliwill K, Adams C, Iyer V, Riva L, Rosario Rd, Fredlund E, Adams D, Balmain A. Genomic Mutational Signatures in Tumors Induced By High and Low Energy Radiation in Trp53-deficient Mouse Models International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.1048 |
0.342 |
|
| 2019 |
Tee P, Balmain A. Critical behavior of spatial networks as a model of paracrine signaling in tumorigenesis Applied Network Science. 4: 47. DOI: 10.1007/S41109-019-0167-7 |
0.344 |
|
| 2018 |
Li S, Balmain A, Counter CM. A model for RAS mutation patterns in cancers: finding the sweet spot. Nature Reviews. Cancer. PMID 30420765 DOI: 10.1038/S41568-018-0076-6 |
0.375 |
|
| 2018 |
Reeves MQ, Kandyba E, Harris S, Del Rosario R, Balmain A. Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis. Nature Cell Biology. 20: 699-709. PMID 29802408 DOI: 10.1038/S41556-018-0109-0 |
0.329 |
|
| 2018 |
Balmain A. Abstract IA15: Normal and cancer stem cells in multistage carcinogenesis Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-Ia15 |
0.49 |
|
| 2017 |
Quigley DA, Tahiri A, Lüders T, Riis MH, Balmain A, Børresen-Dale AL, Bukholm I, Kristensen V. Age, estrogen, and immune response in breast adenocarcinoma and adjacent normal tissue. Oncoimmunology. 6: e1356142. PMID 29147603 DOI: 10.1080/2162402X.2017.1356142 |
0.345 |
|
| 2017 |
Huang PY, Kandyba E, Jabouille A, Sjolund J, Kumar A, Halliwill K, McCreery M, DelRosario R, Kang HC, Wong CE, Seibler J, Beuger V, Pellegrino M, Sciambi A, Eastburn DJ, ... Balmain A, et al. Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma. Nature Genetics. PMID 28945253 DOI: 10.1038/Ng.3957 |
0.388 |
|
| 2016 |
Halliwill KD, Quigley DA, Kang HC, Del Rosario R, Ginzinger D, Balmain A. Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer. Genome Medicine. 8: 83. PMID 27506198 DOI: 10.1186/S13073-016-0334-8 |
0.306 |
|
| 2016 |
Quigley DA, Kandyba E, Huang P, Halliwill KD, Sjölund J, Pelorosso F, Wong CE, Hirst GL, Wu D, Delrosario R, Kumar A, Balmain A. Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer. Cell Reports. PMID 27425619 DOI: 10.1016/J.Celrep.2016.06.061 |
0.405 |
|
| 2016 |
Quigley DA, Tahiri A, Lüders T, Riis MH, Balmain A, Børresen-Dale A, Bukholm IR, Kristensen V. Abstract B59: Age and estrogen-dependent inflammation in breast adenocarcinoma and normal breast tissue Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B59 |
0.338 |
|
| 2016 |
McCreery MQ, Balmain A. Abstract 2376: Clonal evolution of skin carcinomas during tumor progression and metastasis Cancer Research. 76: 2376-2376. DOI: 10.1158/1538-7445.Am2016-2376 |
0.405 |
|
| 2015 |
Wang MT, Holderfield M, Galeas J, Delrosario R, To MD, Balmain A, McCormick F. K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling. Cell. 163: 1237-51. PMID 26590425 DOI: 10.1016/J.Cell.2015.10.041 |
0.332 |
|
| 2015 |
McCreery MQ, Halliwill KD, Chin D, Delrosario R, Hirst G, Vuong P, Jen KY, Hewinson J, Adams DJ, Balmain A. Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers. Nature Medicine. PMID 26523969 DOI: 10.1038/Nm.3979 |
0.444 |
|
| 2015 |
Adams CJ, Yu JS, Mao JH, Jen KY, Costes SV, Wade M, Shoemake J, Aina OH, Del Rosario R, Menchavez PT, Cardiff RD, Wahl GM, Balmain A. The Trp53 delta proline (Trp53ΔP) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development. Molecular Carcinogenesis. PMID 26310697 DOI: 10.1002/Mc.22377 |
0.408 |
|
| 2015 |
Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, et al. Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate. Nature Communications. 6: 6706. PMID 25913614 DOI: 10.1038/Ncomms7706 |
0.36 |
|
| 2015 |
Letteboer TG, Benzinou M, Merrick CB, Quigley DA, Zhau K, Kim IJ, To MD, Jablons DM, van Amstel JK, Westermann CJ, Giraud S, Dupuis-Girod S, Lesca G, Berg JH, Balmain A, et al. Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14. Frontiers in Genetics. 6: 67. PMID 25815003 DOI: 10.3389/Fgene.2015.00067 |
0.34 |
|
| 2015 |
Chen J, Hackett CS, Zhang S, Song YK, Bell RJ, Molinaro AM, Quigley DA, Balmain A, Song JS, Costello JF, Gustafson WC, Van Dyke T, Kwok PY, Khan J, Weiss WA. The genetics of splicing in neuroblastoma. Cancer Discovery. 5: 380-95. PMID 25637275 DOI: 10.1158/2159-8290.Cd-14-0892 |
0.39 |
|
| 2015 |
Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, Delrosario R, Jen KY, Gurley KE, Kemp CJ, Fredlund E, Quigley DA, Adams DJ, Balmain A. The mutational landscapes of genetic and chemical models of Kras-driven lung cancer. Nature. 517: 489-92. PMID 25363767 DOI: 10.1038/Nature13898 |
0.383 |
|
| 2015 |
Quigley D, Silwal-Pandit L, Dannenfelser R, Langerød A, Vollan HK, Vaske C, Siegel JU, Troyanskaya O, Chin SF, Caldas C, Balmain A, Børresen-Dale AL, Kristensen V. Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53. Molecular Cancer Research : McR. 13: 493-501. PMID 25351767 DOI: 10.1158/1541-7786.Mcr-14-0387 |
0.349 |
|
| 2015 |
Song IY, Balmain A. Cellular reprogramming in skin cancer. Seminars in Cancer Biology. 32: 32-39. PMID 24721247 DOI: 10.1016/J.Semcancer.2014.03.006 |
0.381 |
|
| 2015 |
Westcott PM, To MD, Delrosario R, Halliwill KD, Balmain A. Abstract A1-20: Genetic control of Kras mutation specificity in mice Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-20 |
0.414 |
|
| 2015 |
Quigley DA, Vaske C, Silwa-Pandit L, Dannenfelser R, Langerød A, Vollan HKM, Troyanskaya O, Chin S, Caldas C, Balmain A, Børresen-Dale A, Kristensen V. Abstract PR06: Lymphocyte invasion of basal breast tumors is associated with wild-type p53 Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-Pr06 |
0.385 |
|
| 2015 |
Westcott PM, To MD, Delrosario R, Halliwill KD, Vuong P, McCreery MQ, Balmain A. Abstract LB-134: A novel model to investigate Kras mutation specificity in the skin Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-134 |
0.307 |
|
| 2014 |
Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, ... ... Balmain A, et al. Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. Cell Reports. 9: 1034-46. PMID 25437558 DOI: 10.1016/J.Celrep.2014.09.046 |
0.314 |
|
| 2014 |
Balmain A, Yuspa SH. Milestones in skin carcinogenesis: the biology of multistage carcinogenesis. The Journal of Investigative Dermatology. 134: E2-7. PMID 25302469 DOI: 10.1038/Skinbio.2014.2 |
0.387 |
|
| 2014 |
Huang PY, Balmain A. Modeling cutaneous squamous carcinoma development in the mouse. Cold Spring Harbor Perspectives in Medicine. 4: a013623. PMID 25183851 DOI: 10.1101/Cshperspect.A013623 |
0.45 |
|
| 2014 |
Sjölund J, Pelorosso FG, Quigley DA, DelRosario R, Balmain A. Identification of Hipk2 as an essential regulator of white fat development. Proceedings of the National Academy of Sciences of the United States of America. 111: 7373-8. PMID 24785298 DOI: 10.1073/Pnas.1322275111 |
0.362 |
|
| 2014 |
Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V. The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors. Molecular Oncology. 8: 273-84. PMID 24388359 DOI: 10.1016/J.Molonc.2013.11.008 |
0.383 |
|
| 2014 |
Chen J, Hackett CS, Zhang S, Song YK, Molinaro A, Quigley DA, Balmain A, Gustafson WC, Dyke TAV, Kwok P, Khan J, Weiss WA. Abstract 3413: A genetic analysis of splicing in neuroblastoma identifies opposing functions for FUBP1 splice variants in MYC regulation Cancer Research. 74: 3413-3413. DOI: 10.1158/1538-7445.Am2014-3413 |
0.387 |
|
| 2014 |
Barcellos-Hoff MH, Adams C, Balmain A, Costes SV, Demaria S, Illa-Bochaca I, Mao JH, Ouyang H, Sebastiano C, Tang J. Systems biology perspectives on the carcinogenic potential of radiation Journal of Radiation Research. 55. DOI: 10.1093/Jrr/Rrt211 |
0.341 |
|
| 2013 |
Lessard JC, Piña-Paz S, Rotty JD, Hickerson RP, Kaspar RL, Balmain A, Coulombe PA. Keratin 16 regulates innate immunity in response to epidermal barrier breach Proceedings of the National Academy of Sciences of the United States of America. 110: 19537-19542. PMID 24218583 DOI: 10.1073/Pnas.1309576110 |
0.345 |
|
| 2013 |
Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, et al. Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. The Journal of Allergy and Clinical Immunology. 132: 1121-9. PMID 24084074 DOI: 10.1016/J.Jaci.2013.08.046 |
0.339 |
|
| 2013 |
Kim IJ, Quigley D, To MD, Pham P, Lin K, Jo B, Jen KY, Raz D, Kim J, Mao JH, Jablons D, Balmain A. Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas. Nature Communications. 4: 1701. PMID 23591868 DOI: 10.1038/Ncomms2660 |
0.316 |
|
| 2013 |
Wong CE, Yu JS, Quigley DA, To MD, Jen KY, Huang PY, Del Rosario R, Balmain A. Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression. Genes & Development. 27: 670-82. PMID 23512660 DOI: 10.1101/Gad.210427.112 |
0.419 |
|
| 2013 |
Kang HC, Quigley DA, Kim IJ, Wakabayashi Y, Ferguson-Smith MA, D'Alessandro M, Birgitte Lane E, Akhurst RJ, Goudie DR, Balmain A. Multiple self-healing squamous epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology. The Journal of Investigative Dermatology. 133: 1907-10. PMID 23358096 DOI: 10.1038/Jid.2013.45 |
0.347 |
|
| 2013 |
Nguyen DH, Fredlund E, Zhao W, Perou CM, Balmain A, Mao JH, Barcellos-Hoff MH. Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1353-62. PMID 23339125 DOI: 10.1158/1078-0432.Ccr-12-3554 |
0.373 |
|
| 2013 |
Kang HC, Wakabayashi Y, Jen KY, Mao JH, Zoumpourlis V, Del Rosario R, Balmain A. Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice. The Journal of Investigative Dermatology. 133: 1311-20. PMID 23223138 DOI: 10.1038/Jid.2012.419 |
0.411 |
|
| 2013 |
To MD, Rosario RD, Westcott PM, Banta KL, Balmain A. Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis. Oncogene. 32: 4028-33. PMID 22945650 DOI: 10.1038/Onc.2012.404 |
0.409 |
|
| 2013 |
Song IY, Kumar A, Delrosario R, Mao J, Balmain A. Abstract LB-258: The human Aurora-A kinase Phe31Ile polymorphism affects cancer susceptibility in a knock-in mouse model. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-258 |
0.367 |
|
| 2012 |
Kwon YW, Kim IJ, Wu D, Lu J, Stock WA, Liu Y, Huang Y, Kang HC, DelRosario R, Jen KY, Perez-Losada J, Wei G, Balmain A, Mao JH. Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development. Molecular Cancer Research : McR. 10: 834-44. PMID 22513362 DOI: 10.1158/1541-7786.Mcr-12-0025 |
0.385 |
|
| 2012 |
Perez-Losada J, Wu D, DelRosario R, Balmain A, Mao JH. Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility. Plos One. 7: e31301. PMID 22348067 DOI: 10.1371/Journal.Pone.0031301 |
0.441 |
|
| 2012 |
Jen KY, Song IY, Banta KL, Wu D, Mao JH, Balmain A. Sequential mutations in Notch1, Fbxw7, and Tp53 in radiation-induced mouse thymic lymphomas. Blood. 119: 805-9. PMID 22117044 DOI: 10.1182/Blood-2011-01-327619 |
0.352 |
|
| 2012 |
Nguyen DH, Fredlund E, Zhao W, Perou CM, Balmain A, Mao J, Barcellos-Hoff MH. Abstract 4268: Gene signature of host irradiation from Trp53 null mammary tumors detects radiation-preceded human cancers and has prognostic value for sporadic human breast cancer Cancer Research. 72: 4268-4268. DOI: 10.1158/1538-7445.Am2012-4268 |
0.403 |
|
| 2012 |
Quigley D, Loo PV, Alnæs G, Tost J, Zelenika D, Balmain A, Børresen-Dale A, Kristensen V. Abstract P5-05-03: The 5p12 breast cancer susceptibility locus is associated with MRPS30 expression in estrogen receptor - positive tumors Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P5-05-03 |
0.367 |
|
| 2011 |
To MD, Quigley DA, Mao JH, Del Rosario R, Hsu J, Hodgson G, Jacks T, Balmain A. Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer. Molecular Cancer Research : McR. 9: 1339-45. PMID 21807965 DOI: 10.1158/1541-7786.Mcr-11-0219 |
0.392 |
|
| 2011 |
Wang YV, Leblanc M, Fox N, Mao JH, Tinkum KL, Krummel K, Engle D, Piwnica-Worms D, Piwnica-Worms H, Balmain A, Kaushansky K, Wahl GM. Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes & Development. 25: 1426-38. PMID 21724834 DOI: 10.1101/Gad.2024411 |
0.342 |
|
| 2011 |
Quigley DA, To MD, Kim IJ, Lin KK, Albertson DG, Sjolund J, Pérez-Losada J, Balmain A. Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility. Genome Biology. 12: R5. PMID 21244661 DOI: 10.1186/Gb-2011-12-1-R5 |
0.435 |
|
| 2010 |
Pelorosso FG, Balmain A. C/EBPδ: friend or foe? a novel role for C/EBPδ in metastasis. The Embo Journal. 29: 4063-5. PMID 21157479 DOI: 10.1038/Emboj.2010.308 |
0.338 |
|
| 2010 |
Chun MG, Mao JH, Chiu CW, Balmain A, Hanahan D. Polymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17268-73. PMID 20855625 DOI: 10.1073/Pnas.1012705107 |
0.406 |
|
| 2010 |
Climent J, Perez-Losada J, Quigley DA, Kim IJ, Delrosario R, Jen KY, Bosch A, Lluch A, Mao JH, Balmain A. Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 3770-8. PMID 20625127 DOI: 10.1200/Jco.2009.27.0215 |
0.33 |
|
| 2010 |
Workman P, Aboagye EO, Balkwill F, Balmain A, Bruder G, Chaplin DJ, Double JA, Everitt J, Farningham DAH, Glennie MJ, Kelland LR, Robinson V, Stratford IJ, Tozer GM, Watson S, et al. Guidelines for the welfare and use of animals in cancer research British Journal of Cancer. 102: 1555-1577. PMID 20502460 DOI: 10.1038/Sj.Bjc.6605642 |
0.31 |
|
| 2010 |
Li Z, Zhang Q, Mao JH, Weise A, Mrasek K, Fan X, Zhang X, Liehr T, Lu KH, Balmain A, Cai WW. An HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesis Oncogene. 29: 2659-2671. PMID 20154723 DOI: 10.1038/Onc.2010.19 |
0.34 |
|
| 2010 |
Li Z, Zhang Q, Mao J, Weise A, Mrasek K, Fan X, Zhang X, Liehr T, Lu KH, Balmain A, Cai W. Abstract 254: A HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesis Cancer Research. 70: 254-254. DOI: 10.1158/1538-7445.Am10-254 |
0.36 |
|
| 2010 |
To M, Quigley D, Sjolund J, Balmain A. 606 Evolution of genetic and gene expression networks during tumour development Ejc Supplements. 8: 155. DOI: 10.1016/S1359-6349(10)71407-5 |
0.305 |
|
| 2010 |
Yu J, Mao J, Wade M, Del Rosario R, Wu D, Cardiff R, Wahl G, Balmain A. Mice Lacking the Proline-rich Domain of p53 Are Exquisitely Sensitive to Epithelial Tumor Development after Gamma-Irradiation International Journal of Radiation Oncology*Biology*Physics. 78: S88-S89. DOI: 10.1016/J.Ijrobp.2010.07.236 |
0.328 |
|
| 2009 |
Quigley D, Balmain A. Systems genetics analysis of cancer susceptibility: from mouse models to humans. Nature Reviews. Genetics. 10: 651-7. PMID 19636343 DOI: 10.1038/Nrg2617 |
0.352 |
|
| 2009 |
Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B, Solari A, Bobisse S, Rondina MB, Guzzardo V, Parenti AR, Rosato A, Bicciato S, Balmain A, Piccolo S. A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell. 137: 87-98. PMID 19345189 DOI: 10.1016/J.Cell.2009.01.039 |
0.366 |
|
| 2009 |
Quigley DA, To MD, Pérez-Losada J, Pelorosso FG, Mao JH, Nagase H, Ginzinger DG, Balmain A. Genetic architecture of mouse skin inflammation and tumour susceptibility. Nature. 458: 505-8. PMID 19136944 DOI: 10.1038/Nature07683 |
0.4 |
|
| 2008 |
Mahler KL, Fleming JL, Dworkin AM, Gladman N, Cho HY, Mao JH, Balmain A, Toland AE. Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus Bmc Genomics. 9. PMID 19105829 DOI: 10.1186/1471-2164-9-626 |
0.307 |
|
| 2008 |
Mao JH, Kim IJ, Wu D, Climent J, Kang HC, DelRosario R, Balmain A. FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. Science (New York, N.Y.). 321: 1499-502. PMID 18787170 DOI: 10.1126/Science.1162981 |
0.398 |
|
| 2008 |
To MD, Wong CE, Karnezis AN, Del Rosario R, Di Lauro R, Balmain A. Kras regulatory elements and exon 4A determine mutation specificity in lung cancer. Nature Genetics. 40: 1240-4. PMID 18758463 DOI: 10.1038/Ng.211 |
0.408 |
|
| 2008 |
Mao JH, Wu D, DelRosario R, Castellanos A, Balmain A, Perez-Losada J. Atm heterozygosity does not increase tumor susceptibility to ionizing radiation alone or in a p53 heterozygous background Oncogene. 27: 6596-6600. PMID 18679420 DOI: 10.1038/Onc.2008.280 |
0.429 |
|
| 2008 |
Chiaverotti T, Couto SS, Donjacour A, Mao JH, Nagase H, Cardiff RD, Cunha GR, Balmain A. Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer. The American Journal of Pathology. 172: 236-46. PMID 18156212 DOI: 10.2353/Ajpath.2008.070602 |
0.319 |
|
| 2007 |
Wei G, Ku S, Ma GK, Saito S, Tang AA, Zhang J, Mao JH, Appella E, Balmain A, Huang EJ. HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 13040-5. PMID 17666529 DOI: 10.1073/Pnas.0703213104 |
0.375 |
|
| 2007 |
De Koning JP, Wakabayashi Y, Nagase H, Mao JH, Balmain A. Convergence of congenic mapping and allele-specific alterations in tumors for the resolution of the Skts1 skin tumor susceptibility locus Oncogene. 26: 4171-4178. PMID 17311004 DOI: 10.1038/Sj.Onc.1210206 |
0.439 |
|
| 2007 |
Mao JH, Wu D, Perez-Losada J, Jiang T, Li Q, Neve RM, Gray JW, Cai WW, Balmain A. Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice. Cancer Cell. 11: 161-73. PMID 17292827 DOI: 10.1016/J.Ccr.2006.11.025 |
0.41 |
|
| 2007 |
Wakabayashi Y, Mao JH, Brown K, Girardi M, Balmain A. Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice. Nature. 445: 761-5. PMID 17230190 DOI: 10.1038/Nature05489 |
0.412 |
|
| 2006 |
To MD, Perez-Losada J, Mao JH, Hsu J, Jacks T, Balmain A. A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice. Nature Genetics. 38: 926-30. PMID 16823377 DOI: 10.1038/Ng1836 |
0.39 |
|
| 2006 |
Mao JH, Saunier EF, de Koning JP, McKinnon MM, Higgins MN, Nicklas K, Yang HT, Balmain A, Akhurst RJ. Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 103: 8125-30. PMID 16702541 DOI: 10.1073/Pnas.0602581103 |
0.404 |
|
| 2006 |
Lacher MD, Tiirikainen MI, Saunier EF, Christian C, Anders M, Oft M, Balmain A, Akhurst RJ, Korn WM. Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition. Cancer Research. 66: 1648-57. PMID 16452224 DOI: 10.1158/0008-5472.Can-05-2328 |
0.33 |
|
| 2006 |
Balmain A, Montell D. Oncogenes and cell proliferation: Shifting paradigms in the understanding and treatment of cancer Current Opinion in Genetics and Development. 16: 1-3. DOI: 10.1016/J.Gde.2005.12.013 |
0.335 |
|
| 2005 |
To MD, Perez-Losada J, Mao JH, Balmain A. Crosstalk between Pten and Ras signaling pathways in tumor development. Cell Cycle (Georgetown, Tex.). 4: 1185-8. PMID 16123588 DOI: 10.4161/Cc.4.9.2039 |
0.422 |
|
| 2005 |
Mao JH, Li J, Jiang T, Li Q, Wu D, Perez-Losada J, DelRosario R, Peterson L, Balmain A, Cai WW. Genomic instability in radiation-induced mouse lymphoma from p53 heterozygous mice. Oncogene. 24: 7924-34. PMID 16116484 DOI: 10.1038/Sj.Onc.1208926 |
0.364 |
|
| 2005 |
Perez-Losada J, Mao JH, Balmain A. Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway. Cancer Research. 65: 6488-92. PMID 16061623 DOI: 10.1158/0008-5472.Can-05-1294 |
0.431 |
|
| 2005 |
Perez-Losada J, Wu D, DelRosario R, Balmain A, Mao JH. p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo. Oncogene. 24: 5521-4. PMID 16007185 DOI: 10.1038/Sj.Onc.1208799 |
0.349 |
|
| 2005 |
Ewart-Toland A, Dai Q, Gao YT, Nagase H, Dunlop MG, Farrington SM, Barnetson RA, Anton-Culver H, Peel D, Ziogas A, Lin D, Miao X, Sun T, Ostrander EA, Stanford JL, ... ... Balmain A, et al. Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types. Carcinogenesis. 26: 1368-73. PMID 15802297 DOI: 10.1093/Carcin/Bgi085 |
0.342 |
|
| 2004 |
Mao JH, Perez-Losada J, Wu D, Delrosario R, Tsunematsu R, Nakayama KI, Brown K, Bryson S, Balmain A. Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene. Nature. 432: 775-9. PMID 15592418 DOI: 10.1038/Nature03155 |
0.413 |
|
| 2004 |
Hsu SJ, Nagase H, Balmain A. Identification of Fetuin-B as a member of a cystatin-like gene family on mouse chromosome 16 with tumor suppressor activity. Genome / National Research Council Canada = GéNome / Conseil National De Recherches Canada. 47: 931-46. PMID 15499407 DOI: 10.1139/G04-043 |
0.413 |
|
| 2004 |
Hirst GL, Balmain A. Forty years of cancer modelling in the mouse European Journal of Cancer. 40: 1974-1980. PMID 15315806 DOI: 10.1016/J.Ejca.2004.05.013 |
0.368 |
|
| 2004 |
Fraga MF, Herranz M, Espada J, Ballestar E, Paz MF, Ropero S, Erkek E, Bozdogan O, Peinado H, Niveleau A, Mao JH, Balmain A, Cano A, Esteller M. A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors. Cancer Research. 64: 5527-34. PMID 15313885 DOI: 10.1158/0008-5472.Can-03-4061 |
0.308 |
|
| 2004 |
Mao JH, To MD, Perez-Losada J, Wu D, Del Rosario R, Balmain A. Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression. Genes & Development. 18: 1800-5. PMID 15289454 DOI: 10.1101/Gad.1213804 |
0.425 |
|
| 2004 |
Ewart-Toland A, Balmain A. The genetics of cancer susceptibility: from mouse to man. Toxicologic Pathology. 32: 26-30. PMID 15209400 DOI: 10.1080/01926230490424716 |
0.419 |
|
| 2004 |
Girardi M, Oppenheim D, Glusac EJ, Filler R, Balmain A, Tigelaar RE, Hayday AC. Characterizing the protective component of the alphabeta T cell response to transplantable squamous cell carcinoma. The Journal of Investigative Dermatology. 122: 699-706. PMID 15086556 DOI: 10.1111/J.0022-202X.2004.22342.X |
0.357 |
|
| 2003 |
Mao JH, Wu D, Perez-Losada J, Nagase H, DelRosario R, Balmain A. Genetic interactions between Pten and p53 in radiation-induced lymphoma development. Oncogene. 22: 8379-85. PMID 14627978 DOI: 10.1038/Sj.Onc.1207083 |
0.415 |
|
| 2003 |
Hann B, Balmain A. Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants. Journal of Virology. 77: 11588-95. PMID 14557644 DOI: 10.1128/Jvi.77.21.11588-11595.2003 |
0.374 |
|
| 2003 |
Nagase H, Mao JH, Balmain A. Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice. Cancer Research. 63: 4849-53. PMID 12941805 |
0.318 |
|
| 2003 |
de Koning JP, Mao JH, Balmain A. Novel approaches to identify low-penetrance cancer susceptibility genes using mouse models. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 163: 19-27; discussion 26. PMID 12903840 DOI: 10.1007/978-3-642-55647-0_3 |
0.414 |
|
| 2003 |
Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan J, Chan F, MacCarthy-Morrogh L, Ponder BA, Nagase H, Burn J, Ball S, Almeida M, Linardopoulos S, Balmain A. Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nature Genetics. 34: 403-12. PMID 12881723 DOI: 10.1038/Ng1220 |
0.442 |
|
| 2003 |
Perez-Losada J, Balmain A. Stem-cell hierarchy in skin cancer. Nature Reviews. Cancer. 3: 434-43. PMID 12778133 DOI: 10.1038/Nrc1095 |
0.346 |
|
| 2003 |
Balmain A, Gray J, Ponder B. The genetics and genomics of cancer. Nature Genetics. 33: 238-44. PMID 12610533 DOI: 10.1038/Ng1107 |
0.425 |
|
| 2003 |
Mao JH, Balmain A. Genomic approaches to identification of tumour-susceptibility genes using mouse models. Current Opinion in Genetics & Development. 13: 14-9. PMID 12573430 DOI: 10.1016/S0959-437X(03)00005-4 |
0.386 |
|
| 2003 |
Yan W, Kitzes G, Dormishian F, Hawkins L, Sampson-Johannes A, Watanabe J, Holt J, Lee V, Dubensky T, Fattaey A, Hermiston T, Balmain A, Shen Y. Developing novel oncolytic adenoviruses through bioselection. Journal of Virology. 77: 2640-50. PMID 12552003 DOI: 10.1128/Jvi.77.4.2640-2650.2003 |
0.347 |
|
| 2003 |
Hodgson G, Hager J, Chin K, Lapuk C, Volik S, Collins C, Balmain A, Waldman F, Hanahan D, Gray J. The comparative genetics and genomics of cancer: of mice and men. Breast Cancer Research. 5: 24-24. DOI: 10.1186/Bcr683 |
0.41 |
|
| 2002 |
Oft M, Akhurst RJ, Balmain A. Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nature Cell Biology. 4: 487-94. PMID 12105419 DOI: 10.1038/Ncb807 |
0.341 |
|
| 2002 |
Psichari E, Balmain A, Plows D, Zoumpourlis V, Pintzas A. High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling. The Journal of Biological Chemistry. 277: 29490-5. PMID 12039949 DOI: 10.1074/Jbc.M112368200 |
0.345 |
|
| 2002 |
Balmain A. Cancer: new-age tumour suppressors. Nature. 417: 235-7. PMID 12015584 DOI: 10.1038/417235A |
0.379 |
|
| 2002 |
Cai WW, Mao JH, Chow CW, Damani S, Balmain A, Bradley A. Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays. Nature Biotechnology. 20: 393-6. PMID 11923847 DOI: 10.1038/Nbt0402-393 |
0.326 |
|
| 2002 |
Balmain A. Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models. Cell. 108: 145-52. PMID 11832205 DOI: 10.1016/S0092-8674(02)00622-0 |
0.379 |
|
| 2002 |
Bergo MO, Ambroziak P, Gregory C, George A, Otto JC, Kim E, Nagase H, Casey PJ, Balmain A, Young SG. Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. Molecular and Cellular Biology. 22: 171-81. PMID 11739732 DOI: 10.1128/Mcb.22.1.171-181.2002 |
0.359 |
|
| 2002 |
Koning JPd, Ewart-Toland A, Mao J, Nagase H, Balmain A. Session 2 S3. Approaches to identify low penetrance cancer susceptibility genes using mouse models European Journal of Cancer. 38. DOI: 10.1016/S0959-8049(02)80611-6 |
0.353 |
|
| 2001 |
Hann B, Balmain A. Building 'validated' mouse models of human cancer Current Opinion in Cell Biology. 13: 778-784. PMID 11698196 DOI: 10.1016/S0955-0674(00)00283-0 |
0.366 |
|
| 2001 |
Derynck R, Akhurst RJ, Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nature Genetics. 29: 117-29. PMID 11586292 DOI: 10.1038/Ng1001-117 |
0.352 |
|
| 2001 |
Balmain A. Cancer genetics: From Boveri and Mendel to microarrays Nature Reviews Cancer. 1: 77-82. DOI: 10.1038/35094086 |
0.328 |
|
| 2000 |
Linardopoulos S, Silva S, Klein G, Balmain A. Allele-specific loss or imbalance of chromosomes 9, 15, and 16 in B-cell tumors from interspecific F1 hybrid mice carrying Eμ-c-myc or N-myc transgenes International Journal of Cancer. 88: 920-927. PMID 11093815 DOI: 10.1002/1097-0215(20001215)88:6<920::Aid-Ijc13>3.0.Co;2-# |
0.352 |
|
| 2000 |
Zoumpourlis V, Papassava P, Linardopoulos S, Gillespie D, Balmain A, Pintzas A. High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model Oncogene. 19: 4011-4021. PMID 10962557 DOI: 10.1038/Sj.Onc.1203732 |
0.347 |
|
| 2000 |
Balmain A, Harris CC. Carcinogenesis in mouse and human cells: Parallels and paradoxes Carcinogenesis. 21: 371-377. PMID 10688857 DOI: 10.1093/Carcin/21.3.371 |
0.403 |
|
| 2000 |
Ganly I, Mautner V, Balmain A. Productive replication of human adenoviruses in mouse epidermal cells Journal of Virology. 74: 2895-2899. PMID 10684307 DOI: 10.1128/Jvi.74.6.2895-2899.2000 |
0.341 |
|
| 2000 |
Frame S, Balmain A. Integration of positive and negative growth signals during ras pathway activation in vivo Current Opinion in Genetics and Development. 10: 106-113. PMID 10679397 DOI: 10.1016/S0959-437X(99)00052-0 |
0.311 |
|
| 2000 |
Zhu J, Gao B, Zhao J, Balmain A. Targeting gene expression to tumor cells with loss of wild-type p53 function Cancer Gene Therapy. 7: 4-12. PMID 10678350 DOI: 10.1038/Sj.Cgt.7700091 |
0.388 |
|
| 1999 |
Nagase H, Mao JH, Balmain A. A subset of skin tumor modifier loci determines survival time of tumor- bearing mice Proceedings of the National Academy of Sciences of the United States of America. 96: 15032-15037. PMID 10611333 DOI: 10.1073/Pnas.96.26.15032 |
0.428 |
|
| 1999 |
Akhurst RJ, Balmain A. Genetic events and the role of TGFβ in epithelial tumour progression Journal of Pathology. 187: 82-90. PMID 10341708 DOI: 10.1002/(Sici)1096-9896(199901)187:1<82::Aid-Path248>3.0.Co;2-8 |
0.455 |
|
| 1999 |
Dyson N, Balmain A. Oncogenes and cell proliferation: Editorial overview Current Opinion in Genetics and Development. 9: 11-14. PMID 10206674 DOI: 10.1016/S0959-437X(99)80002-1 |
0.305 |
|
| 1998 |
Frame S, Crombie R, Liddell J, Stuart D, Linardopoulos S, Nagase H, Portella G, Brown K, Street A, Akhurst R, Balmain A. Epithelial carcinogenesis in the mouse: Correlating the genetics and the biology Philosophical Transactions of the Royal Society B: Biological Sciences. 353: 839-845. PMID 9684281 DOI: 10.1098/Rstb.1998.0248 |
0.439 |
|
| 1998 |
Balmain A, Nagase H. Cancer resistance genes in mice: Models for the study of tumour modifiers Trends in Genetics. 14: 139-144. PMID 9594661 DOI: 10.1016/S0168-9525(98)01422-X |
0.346 |
|
| 1998 |
Brown K, Strathdee D, Bryson S, Lambie W, Balmain A. The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted. Current Biology : Cb. 8: 516-24. PMID 9560338 DOI: 10.1016/S0960-9822(98)70203-9 |
0.411 |
|
| 1998 |
Mao JH, Lindsay KA, Balmain A, Wheldon TE. Stochastic modelling of tumorigenesis in p53 deficient mice British Journal of Cancer. 77: 243-252. PMID 9460995 DOI: 10.1038/Bjc.1998.40 |
0.326 |
|
| 1997 |
Gause PR, Lluria-Prevatt M, Keith WN, Balmain A, Linardopolous S, Warneke J, Powell MB. Chromosomal and genetic alterations of 7,12-dimethylbenz[a]anthracene- induced melanoma from TP-ras transgenic mice Molecular Carcinogenesis. 20: 78-87. PMID 9328438 DOI: 10.1002/(Sici)1098-2744(199709)20:1<78::Aid-Mc9>3.0.Co;2-E |
0.418 |
|
| 1997 |
Holden PR, McGuire B, Stoler A, Balmain A, Pitts JD. Changes in gap junctional intercellular communication in mouse skin carcinogenesis. Carcinogenesis. 18: 15-21. PMID 9054584 DOI: 10.1093/Carcin/18.1.15 |
0.344 |
|
| 1996 |
Cui W, Fowlis DJ, Bryson S, Duffie E, Ireland H, Balmain A, Akhurst RJ. TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell. 86: 531-42. PMID 8752208 DOI: 10.1016/S0092-8674(00)80127-0 |
0.417 |
|
| 1996 |
Cano A, Gamallo C, Kemp CJ, Benito N, Palacios J, Quintanilla M, Balmain A. Expression pattern of the cell adhesion molecules. E-cadherin, P-cadherin and alpha 6 beta 4 intergrin is altered in pre-malignant skin tumors of p53-deficient mice. International Journal of Cancer. Journal International Du Cancer. 65: 254-62. PMID 8567126 DOI: 10.1002/(Sici)1097-0215(19960117)65:2<254::Aid-Ijc21>3.0.Co;2-C |
0.351 |
|
| 1995 |
Brown K, Burns PA, Balmain A. Transgenic approaches to understanding the mechanisms of chemical carcinogenesis in mouse skin Toxicology Letters. 82: 123-130. PMID 8597039 DOI: 10.1016/0378-4274(95)03549-4 |
0.388 |
|
| 1995 |
Telliez JB, Plumb M, Balmain A, Bailleul B. Regulatory elements in the first intron of the mouse Ha-ras gene Molecular Carcinogenesis. 12: 137-145. PMID 7893367 DOI: 10.1002/Mc.2940120305 |
0.35 |
|
| 1995 |
Nagase H, Bryson S, Cordell H, Kemp CJ, Fee F, Balmain A. Distinct genetic loci control development of benign and malignant skin tumours in mice. Nature Genetics. 10: 424-9. PMID 7670492 DOI: 10.1038/Ng0895-424 |
0.37 |
|
| 1995 |
Linardopoulos S, Street AJ, Quelle DE, Parry D, Peters G, Sherr CJ, Balmain A. Deletion and altered regulation p16INK4a and p15INK4b in undifferentiated mouse skin tumors Cancer Research. 55: 5168-5172. PMID 7585567 |
0.328 |
|
| 1995 |
Brown K, Balmain A. Transgenic mice and squamous multistage skin carcinogenesis Cancer and Metastasis Reviews. 14: 113-124. PMID 7554029 DOI: 10.1007/Bf00665795 |
0.377 |
|
| 1994 |
Brown K, Kemp C, Burns P, Balmain A. Importance of genetic alterations in tumour development. Archives of Toxicology. Supplement. = Archiv Fã¼R Toxikologie. Supplement. 16: 253-60. PMID 8192588 DOI: 10.1007/978-3-642-78640-2_28 |
0.355 |
|
| 1994 |
Wright JH, McDonnell S, Portella G, Bowden GT, Balmain A, Matrisian LM. A switch from stromal to tumor cell expression of stromelysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression. Molecular Carcinogenesis. 10: 207-15. PMID 8068181 DOI: 10.1002/Mc.2940100405 |
0.386 |
|
| 1994 |
Kemp CJ, Wheldon T, Balmain A. p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis. Nature Genetics. 8: 66-9. PMID 7987394 DOI: 10.1038/Ng0994-66 |
0.336 |
|
| 1994 |
Bremner R, Kemp CJ, Balmain A. Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors. Molecular Carcinogenesis. 11: 90-7. PMID 7916997 DOI: 10.1002/Mc.2940110206 |
0.43 |
|
| 1994 |
Portella G, Liddell J, Crombie R, Haddow S, Clarke M, Stoler AB, Balmain A. Molecular mechanisms of invasion and metastasis during mouse skin tumour progression Invasion and Metastasis. 14: 7-16. PMID 7657534 |
0.309 |
|
| 1994 |
Kemp CJ, Burns PA, Brown K, Nagase H, Balmain A. Transgenic approaches to the analysis of ras and p53 function in multistage carcinogenesis Cold Spring Harbor Symposia On Quantitative Biology. 59: 427-434. PMID 7587097 DOI: 10.1101/Sqb.1994.059.01.048 |
0.302 |
|
| 1993 |
Fowlis DJ, Balmain A. Oncogenes and tumour suppressor genes in transgenic mouse models of neoplasia European Journal of Cancer. 29: 638-645. PMID 8435223 DOI: 10.1016/S0959-8049(05)80170-4 |
0.361 |
|
| 1993 |
Kemp CJ, Donehower LA, Bradley A, Balmain A. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors Cell. 74: 813-822. PMID 8374952 DOI: 10.1016/0092-8674(93)90461-X |
0.431 |
|
| 1993 |
Brown K, Kemp CJ, Burns PA, Stoler AB, Fowlis DJ, Akhurst RJ, Balmain A. Positive and negative growth control in multistage skin carcinogenesis Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 128: 309-321. PMID 8356328 DOI: 10.1007/978-3-642-84881-0_23 |
0.377 |
|
| 1993 |
Kemp CJ, Bremner R, Balmain A. A revised map position for the Ha-ras gene on mouse chromosome 7: Implications for analysis of genetic alterations in rodent tumors Molecular Carcinogenesis. 7: 147-150. PMID 8098216 DOI: 10.1002/Mc.2940070304 |
0.395 |
|
| 1993 |
Stoler AB, Stenback F, Balmain A. The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event Journal of Cell Biology. 122: 1103-1117. PMID 7689080 DOI: 10.1083/Jcb.122.5.1103 |
0.393 |
|
| 1991 |
Plumb M, Telliez JB, Fee F, Daubersies P, Bailleul B, Balmain A. Structural analysis of the mouse c-Ha-ras gene promoter Molecular Carcinogenesis. 4: 103-110. PMID 2043251 DOI: 10.1002/Mc.2940040205 |
0.339 |
|
| 1991 |
Quintanilla M, Haddow S, Jones D, Jaffe D, Bowden GT, Balmain A. Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo Carcinogenesis. 12: 1875-1881. PMID 1934268 DOI: 10.1093/Carcin/12.10.1875 |
0.391 |
|
| 1991 |
Buchmann A, Ruggeri B, Klein-Szanto AJP, Balmain A. Progression of Squamous Carcinoma Cells to Spindle Carcinomas of Mouse Skin Is Associated with an Imbalance of H-ras Alleles on Chromosome 7 Cancer Research. 51: 4097-4101. PMID 1855225 |
0.327 |
|
| 1991 |
Balmain A, Kemp CJ, Burns PA, Stoler AB, Fowlis DJ, Akhurst RJ. Functional loss of tumour suppressor genes in multistage chemical carcinogenesis Princess Takamatsu Symposia. 22: 97-108. PMID 1844254 |
0.328 |
|
| 1991 |
Burns PA, Kemp CJ, Gannon JV, Lane DP, Bremner R, Balmain A. Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice Oncogene. 6: 2363-2369. PMID 1766680 |
0.35 |
|
| 1991 |
Burns PA, Bremner R, Balmain A. Genetic changes during mouse skin tumorigenesis Environmental Health Perspectives. 93: 41-44. PMID 1685445 DOI: 10.1289/Ehp.919341 |
0.414 |
|
| 1990 |
Bremner R, Balmain A. Genetic changes in skin tumor progression: Correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7 Cell. 61: 407-417. PMID 2185890 DOI: 10.1016/0092-8674(90)90523-H |
0.432 |
|
| 1990 |
Brown K, Buchmann A, Balmain A. Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression Proceedings of the National Academy of Sciences of the United States of America. 87: 538-542. PMID 2105486 DOI: 10.1073/Pnas.87.2.538 |
0.383 |
|
| 1990 |
Bailleul B, Surani MA, White S, Barton SC, Brown K, Blessing M, Jorcano J, Balmain A. Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter Cell. 62: 697-708. PMID 1696852 DOI: 10.1016/0092-8674(90)90115-U |
0.422 |
|
| 1989 |
Bailleul B, Brown K, Ramsden M, Akhurst RJ, Fee F, Balmain A. Chemical induction of oncogene mutations and growth factor activity in mouse skin carcinogenesis Environmental Health Perspectives. 81: 23-27. PMID 2667981 DOI: 10.1289/Ehp.898123 |
0.45 |
|
| 1988 |
Brown K, Bailleul B, Ramsden M, Fee F, Krumlauf R, Balmain A. Isolation and characterization of the 5' flanking region of the mouse c-Harvey-ras gene Molecular Carcinogenesis. 1: 161-170. PMID 3074812 DOI: 10.1002/Mc.2940010304 |
0.361 |
|
| 1988 |
Bailleul B, Lang J, Wilkie N, Balmain A. A human T24 ha-ras cassette suitable for expression studies in eukaryotic cells Nucleic Acids Research. 16: 359. PMID 2829123 DOI: 10.1093/Nar/16.1.359 |
0.308 |
|
| 1988 |
Balmain A, Brown K. Oncogene Activation in Chemical Carcinogenesis Advances in Cancer Research. 51: 147-182. DOI: 10.1016/S0065-230X(08)60222-5 |
0.399 |
|
| 1986 |
Brown K, Quintanilla M, Ramsden M, Kerr IB, Young S, Balmain A. v-ras genes from harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis Cell. 46: 447-456. PMID 3015415 DOI: 10.1016/0092-8674(86)90665-3 |
0.395 |
|
| 1986 |
Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis Nature. 322: 78-80. PMID 3014349 DOI: 10.1038/322078A0 |
0.39 |
|
| 1986 |
Balmain A, Quintanilla M, Brown K, Ramsden M, Fee F, Young S. The role of ras gene mutations in initiation of chemical carcinogenesis Leukemia Research. 10: 737-738. DOI: 10.1016/0145-2126(86)90284-5 |
0.344 |
|
| 1985 |
Ramsden M, Cole G, Smith J, Balmain A. Differential methylation of the c-H-ras gene in normal mouse cells and during skin tumour progression Embo Journal. 4: 1449-1454. PMID 4029120 DOI: 10.1002/J.1460-2075.1985.Tb03801.X |
0.352 |
|
| 1985 |
Kerr IB, Lee FD, Quintanilla M, Balmain A. Immunocytochemical demonstration of p21 ras family oncogene product in normal mucosa and in premalignant and malignant tumours of the colorectum British Journal of Cancer. 52: 695-700. PMID 3904802 DOI: 10.1038/Bjc.1985.245 |
0.353 |
|
| 1984 |
Balmain A, Ramsden M, Bowden GT, Smith J. Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas Nature. 307: 658-660. PMID 6694757 DOI: 10.1038/307658A0 |
0.401 |
|
| 1983 |
Balmain A, Pragnell IB. Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene Nature. 303: 72-74. PMID 6843661 DOI: 10.1038/303072A0 |
0.387 |
|
| 1983 |
Koury MJ, Balmain A, Pragnell IB. Induction of granulocyte-macrophage colony-stimulating activity in mouse skin by inflammatory agents and tumor promoters Embo Journal. 2: 1877-1882. PMID 6605850 DOI: 10.1002/J.1460-2075.1983.Tb01674.X |
0.329 |
|
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