Gerd A. Blobel - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Genetics

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA. Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription. Cell Reports. 27: 400-415.e5. PMID 30970245 DOI: 10.1016/j.celrep.2019.03.057  0.4
2018 Bartman CR, Hamagami N, Keller CA, Giardine B, Hardison RC, Blobel GA, Raj A. Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation. Molecular Cell. PMID 30554946 DOI: 10.1016/j.molcel.2018.11.004  0.4
2018 Grevet JD, Lan X, Hamagami N, Edwards CR, Sankaranarayanan L, Ji X, Bhardwaj SK, Face CJ, Posocco DF, Abdulmalik O, Keller CA, Giardine B, Sidoli S, Garcia BA, Chou ST, ... ... Blobel GA, et al. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells. Science (New York, N.Y.). 361: 285-290. PMID 30026227 DOI: 10.1126/science.aao0932  0.4
2018 Wai DC, Szyszka TN, Campbell AE, Kwong C, Wilkinson-White LE, Silva APG, Low JKK, Kwan AH, Gamsjaeger R, Chalmers JN, Patrick WM, Lu B, Vakoc CR, Blobel G, Mackay JP. The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators. The Journal of Biological Chemistry. PMID 29567837 DOI: 10.1074/jbc.RA117.000678  0.92
2018 Behera V, Evans P, Face CJ, Hamagami N, Sankaranarayanan L, Keller CA, Giardine B, Tan K, Hardison RC, Shi J, Blobel GA. Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility. Nature Communications. 9: 782. PMID 29472540 DOI: 10.1038/s41467-018-03082-6  0.4
2017 Huang P, Keller CA, Giardine B, Grevet JD, Davies JOJ, Hughes JR, Kurita R, Nakamura Y, Hardison RC, Blobel GA. Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element. Genes & Development. PMID 28916711 DOI: 10.1101/gad.303461.117  0.4
2017 Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA. The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Molecular Cell. 66: 102-116.e7. PMID 28388437 DOI: 10.1016/j.molcel.2017.02.027  0.4
2017 Deng W, Blobel GA. Detecting Long-Range Enhancer-Promoter Interactions by Quantitative Chromosome Conformation Capture. Methods in Molecular Biology (Clifton, N.J.). 1468: 51-62. PMID 27662870 DOI: 10.1007/978-1-4939-4035-6_6  0.96
2016 Stonestrom AJ, Hsu SC, Werner MT, Blobel GA. Erythropoiesis provides a BRD's eye view of BET protein function. Drug Discovery Today. Technologies. 19: 23-28. PMID 27769353 DOI: 10.1016/j.ddtec.2016.05.004  0.32
2016 Xia Q, Chesi A, Manduchi E, Johnston BT, Lu S, Leonard ME, Parlin UW, Rappaport EF, Huang P, Wells AD, Blobel GA, Johnson ME, Grant SF. The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5. Diabetologia. PMID 27539148 DOI: 10.1007/s00125-016-4077-2  1
2016 Traxler EA, Yao Y, Wang YD, Woodard KJ, Kurita R, Nakamura Y, Hughes JR, Hardison RC, Blobel GA, Li C, Weiss MJ. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition. Nature Medicine. PMID 27525524 DOI: 10.1038/nm.4170  0.4
2016 Breda L, Motta I, Lourenco S, Gemmo C, Deng W, Rupon JW, Abdulmalik OY, Manwani D, Blobel GA, Rivella S. Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers. Blood. PMID 27405777 DOI: 10.1182/blood-2016-01-691089  0.96
2016 Hsiung CC, Bartman CR, Huang P, Ginart P, Stonestrom AJ, Keller CA, Face C, Jahn KS, Evans P, Sankaranarayanan L, Giardine B, Hardison RC, Raj A, Blobel GA. A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition. Genes & Development. 30: 1423-39. PMID 27340175 DOI: 10.1101/gad.280859.116  1
2016 Bartman CR, Hsu SC, Hsiung CC, Raj A, Blobel GA. Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping. Molecular Cell. PMID 27067601 DOI: 10.1016/j.molcel.2016.03.007  1
2016 Paralkar VR, Taborda CC, Huang P, Yao Y, Kossenkov AV, Prasad R, Luan J, Davies JO, Hughes JR, Hardison RC, Blobel GA, Weiss MJ. Unlinking an lncRNA from Its Associated cis Element. Molecular Cell. PMID 27041223 DOI: 10.1016/j.molcel.2016.02.029  1
2016 Naraparaju K, Kolla V, Zhuang T, Higashi M, Iyer R, Kolla S, Okawa ER, Blobel GA, Brodeur GM. Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas. Oncotarget. PMID 26895110 DOI: 10.18632/oncotarget.7434  1
2015 Lee K, Hsiung CC, Huang P, Raj A, Blobel GA. Dynamic enhancer-gene body contacts during transcription elongation. Genes & Development. 29: 1992-7. PMID 26443845 DOI: 10.1101/gad.255265.114  1
2015 Blobel G, Bodine D, Brand M, Crispino J, De Bruijn M, Nathan D, Pappayannopoulou T, Porcher C, Strouboulis J, Zon L, Higgs DR, Stamatoyannopoulos G, Engel JD. An International Effort to Cure a Global Health Problem: A report on the 19th Hemoglobin Switching Conference. Experimental Hematology. PMID 26143582 DOI: 10.1016/j.exphem.2015.06.008  1
2015 Dogan N, Wu W, Morrissey CS, Chen KB, Stonestrom A, Long M, Keller CA, Cheng Y, Jain D, Visel A, Pennacchio LA, Weiss MJ, Blobel GA, Hardison RC. Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility. Epigenetics & Chromatin. 8: 16. PMID 25984238 DOI: 10.1186/s13072-015-0009-5  1
2015 Kolla V, Naraparaju K, Zhuang T, Higashi M, Kolla S, Blobel GA, Brodeur GM. The tumour suppressor CHD5 forms a NuRD-type chromatin remodelling complex. The Biochemical Journal. 468: 345-52. PMID 25825869 DOI: 10.1042/BJ20150030  1
2015 Stonestrom AJ, Hsu SC, Jahn KS, Huang P, Keller CA, Giardine BM, Kadauke S, Campbell AE, Evans P, Hardison RC, Blobel GA. Functions of BET proteins in erythroid gene expression. Blood. 125: 2825-34. PMID 25696920 DOI: 10.1182/blood-2014-10-607309  1
2015 Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL. Characterization of BRD4 during mammalian postmeiotic sperm development. Molecular and Cellular Biology. 35: 1433-48. PMID 25691659 DOI: 10.1128/MCB.01328-14  1
2015 Byrska-Bishop M, VanDorn D, Campbell AE, Betensky M, Arca PR, Yao Y, Gadue P, Costa FF, Nemiroff RL, Blobel GA, French DL, Hardison RC, Weiss MJ, Chou ST. Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus. The Journal of Clinical Investigation. 125: 993-1005. PMID 25621499 DOI: 10.1172/JCI75714  1
2015 Hsiung CC, Morrissey CS, Udugama M, Frank CL, Keller CA, Baek S, Giardine B, Crawford GE, Sung MH, Hardison RC, Blobel GA. Genome accessibility is widely preserved and locally modulated during mitosis. Genome Research. 25: 213-25. PMID 25373146 DOI: 10.1101/gr.180646.114  1
2014 Grevet JD, Blobel GA. Keeping fetal hemoglobin in the loop. Cell Cycle (Georgetown, Tex.). 13: 3153-4. PMID 25485488 DOI: 10.4161/15384101.2014.969995  1
2014 Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, ... ... Blobel GA, et al. A comparative encyclopedia of DNA elements in the mouse genome. Nature. 515: 355-64. PMID 25409824 DOI: 10.1038/nature13992  0.4
2014 Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, et al. Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 111: E4946-53. PMID 25369933 DOI: 10.1073/pnas.1407079111  1
2014 Pimkin M, Kossenkov AV, Mishra T, Morrissey CS, Wu W, Keller CA, Blobel GA, Lee D, Beer MA, Hardison RC, Weiss MJ. Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis. Genome Research. 24: 1932-44. PMID 25319996 DOI: 10.1101/gr.164178.113  1
2014 Wu W, Morrissey CS, Keller CA, Mishra T, Pimkin M, Blobel GA, Weiss MJ, Hardison RC. Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis. Genome Research. 24: 1945-62. PMID 25319994 DOI: 10.1101/gr.164830.113  1
2014 Clifton MK, Westman BJ, Thong SY, O'Connell MR, Webster MW, Shepherd NE, Quinlan KG, Crossley M, Blobel GA, Mackay JP. The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. Plos One. 9: e106011. PMID 25162672 DOI: 10.1371/journal.pone.0106011  1
2014 Deng W, Rupon JW, Krivega I, Breda L, Motta I, Jahn KS, Reik A, Gregory PD, Rivella S, Dean A, Blobel GA. Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell. 158: 849-60. PMID 25126789 DOI: 10.1016/j.cell.2014.05.050  1
2014 Alqarni SS, Murthy A, Zhang W, Przewloka MR, Silva AP, Watson AA, Lejon S, Pei XY, Smits AH, Kloet SL, Wang H, Shepherd NE, Stokes PH, Blobel GA, Vermeulen M, et al. Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex. The Journal of Biological Chemistry. 289: 21844-55. PMID 24920672 DOI: 10.1074/jbc.M114.558940  1
2014 Deng W, Blobel GA. Manipulating nuclear architecture. Current Opinion in Genetics & Development. 25: 1-7. PMID 24584091 DOI: 10.1016/j.gde.2013.10.014  1
2014 Campbell AE, Hsiung CC, Blobel GA. Comparative analysis of mitosis-specific antibodies for bulk purification of mitotic populations by fluorescence-activated cell sorting. Biotechniques. 56: 90-1, 93-4. PMID 24502799 DOI: 10.2144/000114137  1
2013 Zheng R, Rebolledo-Jaramillo B, Zong Y, Wang L, Russo P, Hancock W, Stanger BZ, Hardison RC, Blobel GA. Function of GATA factors in the adult mouse liver. Plos One. 8: e83723. PMID 24367609 DOI: 10.1371/journal.pone.0083723  1
2013 Shi J, Whyte WA, Zepeda-Mendoza CJ, Milazzo JP, Shen C, Roe JS, Minder JL, Mercan F, Wang E, Eckersley-Maslin MA, Campbell AE, Kawaoka S, Shareef S, Zhu Z, Kendall J, ... ... Blobel GA, et al. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes & Development. 27: 2648-62. PMID 24285714 DOI: 10.1101/gad.232710.113  1
2013 Hardison RC, Blobel GA. Genetics. GWAS to therapy by genome edits? Science (New York, N.Y.). 342: 206-7. PMID 24115432 DOI: 10.1126/science.1245813  1
2013 Blobel GA, Hardison RC. A cluster to remember. Cell. 154: 718-20. PMID 23953105 DOI: 10.1016/j.cell.2013.07.041  1
2013 Campbell AE, Wilkinson-White L, Mackay JP, Matthews JM, Blobel GA. Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood. 121: 5218-27. PMID 23704091 DOI: 10.1182/blood-2013-03-488080  1
2013 Kadauke S, Blobel GA. Mitotic bookmarking by transcription factors. Epigenetics & Chromatin. 6: 6. PMID 23547918 DOI: 10.1186/1756-8935-6-6  1
2013 Lai F, Orom UA, Cesaroni M, Beringer M, Taatjes DJ, Blobel GA, Shiekhattar R. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature. 494: 497-501. PMID 23417068 DOI: 10.1038/nature11884  1
2012 Kadauke S, Blobel GA. "Remembering" tissue-specific transcription patterns through mitosis. Cell Cycle (Georgetown, Tex.). 11: 3911-2. PMID 23032269 DOI: 10.4161/cc.22237  1
2012 Kadauke S, Udugama MI, Pawlicki JM, Achtman JC, Jain DP, Cheng Y, Hardison RC, Blobel GA. Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell. 150: 725-37. PMID 22901805 DOI: 10.1016/j.cell.2012.06.038  1
2012 Stamatoyannopoulos JA, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert DM, Groudine M, Bender M, Kaul R, Canfield T, Giste E, Johnson A, Zhang M, Balasundaram G, ... ... Blobel GA, et al. An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biology. 13: 418. PMID 22889292 DOI: 10.1186/gb-2012-13-8-418  1
2012 Deng W, Lee J, Wang H, Miller J, Reik A, Gregory PD, Dean A, Blobel GA. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell. 149: 1233-44. PMID 22682246 DOI: 10.1016/j.cell.2012.03.051  1
2012 Stamatoyannopoulos JA, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert DM, Groudine M, Bender M, Kaul R, Canfield T, Giste E, Johnson A, Zhang M, Balasundaram G, Byron R, ... ... Blobel GA, et al. An encyclopedia of mouse DNA elements (Mouse ENCODE) Genome Biology. 418. DOI: 10.1186/gb4035  1
2011 Wang Y, Meng R, Hayes V, Fuentes R, Yu X, Abrams CS, Heijnen HF, Blobel GA, Marks MS, Poncz M. Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction. Blood. 118: 6183-91. PMID 21989988 DOI: 10.1182/blood-2011-06-363580  1
2011 Blobel GA, Kalota A, Sanchez PV, Carroll M. Short hairpin RNA screen reveals bromodomain proteins as novel targets in acute myeloid leukemia. Cancer Cell. 20: 287-8. PMID 21907920 DOI: 10.1016/j.ccr.2011.08.019  1
2011 Wu W, Cheng Y, Keller CA, Ernst J, Kumar SA, Mishra T, Morrissey C, Dorman CM, Chen KB, Drautz D, Giardine B, Shibata Y, Song L, Pimkin M, Crawford GE, ... ... Blobel GA, et al. Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Research. 21: 1659-71. PMID 21795386 DOI: 10.1101/gr.125088.111  1
2011 Gamsjaeger R, Webb SR, Lamonica JM, Billin A, Blobel GA, Mackay JP. Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Molecular and Cellular Biology. 31: 2632-40. PMID 21555453 DOI: 10.1128/MCB.05413-11  1
2011 Lamonica JM, Deng W, Kadauke S, Campbell AE, Gamsjaeger R, Wang H, Cheng Y, Billin AN, Hardison RC, Mackay JP, Blobel GA. Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proceedings of the National Academy of Sciences of the United States of America. 108: E159-68. PMID 21536911 DOI: 10.1073/pnas.1102140108  1
2011 Lejon S, Thong SY, Murthy A, AlQarni S, Murzina NV, Blobel GA, Laue ED, Mackay JP. Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. The Journal of Biological Chemistry. 286: 1196-203. PMID 21047798 DOI: 10.1074/jbc.M110.195842  1
2010 Zheng R, Blobel GA. GATA Transcription Factors and Cancer. Genes & Cancer. 1: 1178-88. PMID 21779441 DOI: 10.1177/1947601911404223  1
2010 Deng W, Blobel GA. Do chromatin loops provide epigenetic gene expression states? Current Opinion in Genetics & Development. 20: 548-54. PMID 20598523 DOI: 10.1016/j.gde.2010.06.007  1
2010 Bersenev A, Wu C, Balcerek J, Jing J, Kundu M, Blobel GA, Chikwava KR, Tong W. Lnk constrains myeloproliferative diseases in mice. The Journal of Clinical Investigation. 120: 2058-69. PMID 20458146 DOI: 10.1172/JCI42032  1
2010 Miccio A, Blobel GA. Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes. Molecular and Cellular Biology. 30: 3460-70. PMID 20439494 DOI: 10.1128/MCB.00001-10  1
2010 Ye Y, Pringle LM, Lau AW, Riquelme DN, Wang H, Jiang T, Lev D, Welman A, Blobel GA, Oliveira AM, Chou MM. TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB. Oncogene. 29: 3619-29. PMID 20418905 DOI: 10.1038/onc.2010.116  1
2010 Gregory GD, Miccio A, Bersenev A, Wang Y, Hong W, Zhang Z, Poncz M, Tong W, Blobel GA. FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood. 115: 2156-66. PMID 20065294 DOI: 10.1182/blood-2009-10-251280  1
2010 Miccio A, Wang Y, Hong W, Gregory GD, Wang H, Yu X, Choi JK, Shelat S, Tong W, Poncz M, Blobel GA. NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. The Embo Journal. 29: 442-56. PMID 19927129 DOI: 10.1038/emboj.2009.336  1
2009 Blobel GA, Kadauke S, Wang E, Lau AW, Zuber J, Chou MM, Vakoc CR. A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Molecular Cell. 36: 970-83. PMID 20064463 DOI: 10.1016/j.molcel.2009.12.001  1
2009 Cheng Y, Wu W, Kumar SA, Yu D, Deng W, Tripic T, King DC, Chen KB, Zhang Y, Drautz D, Giardine B, Schuster SC, Miller W, Chiaromonte F, Zhang Y, ... Blobel GA, et al. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Research. 19: 2172-84. PMID 19887574 DOI: 10.1101/gr.098921.109  1
2009 Chou ST, Khandros E, Bailey LC, Nichols KE, Vakoc CR, Yao Y, Huang Z, Crispino JD, Hardison RC, Blobel GA, Weiss MJ. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood. 114: 983-94. PMID 19491391 DOI: 10.1182/blood-2009-03-207944  1
2009 Vakoc CR, Wen YY, Gibbs RA, Johnstone CN, Rustgi AK, Blobel GA. Low frequency of MLL3 mutations in colorectal carcinoma. Cancer Genetics and Cytogenetics. 189: 140-1. PMID 19215798 DOI: 10.1016/j.cancergencyto.2008.10.014  1
2009 Tripic T, Deng W, Cheng Y, Zhang Y, Vakoc CR, Gregory GD, Hardison RC, Blobel GA. SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood. 113: 2191-201. PMID 19011221 DOI: 10.1182/blood-2008-07-169417  1
2009 Kadauke S, Blobel GA. Chromatin loops in gene regulation. Biochimica Et Biophysica Acta. 1789: 17-25. PMID 18675948 DOI: 10.1016/j.bbagrm.2008.07.002  1
2009 Blobel GA, Weiss MJ. Nuclear factors that regulate erythropoiesis Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management, Second Edition. 62-85. DOI: 10.1017/CBO9780511596582.008  1
2008 Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Molecular and Cellular Biology. 28: 2825-39. PMID 18285465 DOI: 10.1128/MCB.02076-07  1
2008 Jing H, Vakoc CR, Ying L, Mandat S, Wang H, Zheng X, Blobel GA. Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus. Molecular Cell. 29: 232-42. PMID 18243117 DOI: 10.1016/j.molcel.2007.11.020  1
2008 Roche AE, Bassett BJ, Samant SA, Hong W, Blobel GA, Svensson EC. The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex. Journal of Molecular and Cellular Cardiology. 44: 352-60. PMID 18067919 DOI: 10.1016/j.yjmcc.2007.10.023  1
2007 Gregory GD, Vakoc CR, Rozovskaia T, Zheng X, Patel S, Nakamura T, Canaani E, Blobel GA. Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes. Molecular and Cellular Biology. 27: 8466-79. PMID 17923682 DOI: 10.1128/MCB.00993-07  1
2007 Kim SI, Bultman SJ, Jing H, Blobel GA, Bresnick EH. Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation. Molecular and Cellular Biology. 27: 4551-65. PMID 17438135 DOI: 10.1128/MCB.00235-07  1
2007 Muntean AG, Pang L, Poncz M, Dowdy SF, Blobel GA, Crispino JD. Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood. 109: 5199-207. PMID 17317855 DOI: 10.1182/blood-2006-11-059378  1
2007 Blobel GA. Krüppeling megakaryopoiesis Blood. 110: 3823-3824. DOI: 10.1182/blood-2007-09-110999  1
2006 Zeng PY, Vakoc CR, Chen ZC, Blobel GA, Berger SL. In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. Biotechniques. 41: 694, 696, 698. PMID 17191611 DOI: 10.2144/000112297  1
2006 Vakoc CR, Sachdeva MM, Wang H, Blobel GA. Profile of histone lysine methylation across transcribed mammalian chromatin. Molecular and Cellular Biology. 26: 9185-95. PMID 17030614 DOI: 10.1128/MCB.01529-06  1
2006 Grass JA, Jing H, Kim SI, Martowicz ML, Pal S, Blobel GA, Bresnick EH. Distinct functions of dispersed GATA factor complexes at an endogenous gene locus. Molecular and Cellular Biology. 26: 7056-67. PMID 16980610 DOI: 10.1128/MCB.01033-06  1
2006 Lamonica JM, Vakoc CR, Blobel GA. Acetylation of GATA-1 is required for chromatin occupancy. Blood. 108: 3736-8. PMID 16888089 DOI: 10.1182/blood-2006-07-032847  1
2006 Pang L, Xue HH, Szalai G, Wang X, Wang Y, Watson DK, Leonard WJ, Blobel GA, Poncz M. Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins. Blood. 108: 2198-206. PMID 16757682 DOI: 10.1182/blood-2006-04-019760  1
2006 Blobel GA. GATA-1 caught in the AKT Blood. 107: 851-852. DOI: 10.1182/blood-2005-11-4504  1
2005 Vakoc CR, Mandat SA, Olenchock BA, Blobel GA. Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Molecular Cell. 19: 381-91. PMID 16061184 DOI: 10.1016/j.molcel.2005.06.011  1
2005 Hong W, Nakazawa M, Chen YY, Kori R, Vakoc CR, Rakowski C, Blobel GA. FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. The Embo Journal. 24: 2367-78. PMID 15920470 DOI: 10.1038/sj.emboj.7600703  1
2005 Vakoc CR, Letting DL, Gheldof N, Sawado T, Bender MA, Groudine M, Weiss MJ, Dekker J, Blobel GA. Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Molecular Cell. 17: 453-62. PMID 15694345 DOI: 10.1016/j.molcel.2004.12.028  1
2004 Patel JH, Du Y, Ard PG, Phillips C, Carella B, Chen CJ, Rakowski C, Chatterjee C, Lieberman PM, Lane WS, Blobel GA, McMahon SB. The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. Molecular and Cellular Biology. 24: 10826-34. PMID 15572685 DOI: 10.1128/MCB.24.24.10826-10834.2004  1
2004 Bayly R, Chuen L, Currie RA, Hyndman BD, Casselman R, Blobel GA, LeBrun DP. E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells. The Journal of Biological Chemistry. 279: 55362-71. PMID 15507449 DOI: 10.1074/jbc.M408654200  1
2004 Song S, Cooperman J, Letting DL, Blobel GA, Choi JK. Identification of cyclin D3 as a direct target of E2A using DamID. Molecular and Cellular Biology. 24: 8790-802. PMID 15367695 DOI: 10.1128/MCB.24.19.8790-8802.2004  1
2004 Welch JJ, Watts JA, Vakoc CR, Yao Y, Wang H, Hardison RC, Blobel GA, Chodosh LA, Weiss MJ. Global regulation of erythroid gene expression by transcription factor GATA-1. Blood. 104: 3136-47. PMID 15297311 DOI: 10.1182/blood-2004-04-1603  1
2004 Anguita E, Hughes J, Heyworth C, Blobel GA, Wood WG, Higgs DR. Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2. The Embo Journal. 23: 2841-52. PMID 15215894 DOI: 10.1038/sj.emboj.7600274  1
2004 Letting DL, Chen YY, Rakowski C, Reedy S, Blobel GA. Context-dependent regulation of GATA-1 by friend of GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 101: 476-81. PMID 14695898 DOI: 10.1073/pnas.0306315101  1
2003 Rylski M, Welch JJ, Chen YY, Letting DL, Diehl JA, Chodosh LA, Blobel GA, Weiss MJ. GATA-1-mediated proliferation arrest during erythroid maturation. Molecular and Cellular Biology. 23: 5031-42. PMID 12832487 DOI: 10.1128/MCB.23.14.5031-5042.2003  1
2003 Deng Z, Chen CJ, Chamberlin M, Lu F, Blobel GA, Speicher D, Cirillo LA, Zaret KS, Lieberman PM. The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation. Molecular and Cellular Biology. 23: 2633-44. PMID 12665567 DOI: 10.1128/MCB.23.8.2633-2644.2003  1
2003 Letting DL, Rakowski C, Weiss MJ, Blobel GA. Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1. Molecular and Cellular Biology. 23: 1334-40. PMID 12556492 DOI: 10.1128/MCB.23.4.1334-1340.2003  1
2002 Hong W, Resnick RJ, Rakowski C, Shalloway D, Taylor SJ, Blobel GA. Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68. Molecular Cancer Research : McR. 1: 48-55. PMID 12496368  1
2002 Wang X, Crispino JD, Letting DL, Nakazawa M, Poncz M, Blobel GA. Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors. The Embo Journal. 21: 5225-34. PMID 12356738 DOI: 10.1093/emboj/cdf527  1
2002 Johnson KD, Grass JA, Boyer ME, Kiekhaefer CM, Blobel GA, Weiss MJ, Bresnick EH. Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 11760-5. PMID 12193659 DOI: 10.1073/pnas.192285999  1
2002 Kihm AJ, Kong Y, Hong W, Russell JE, Rouda S, Adachl K, Simon MC, Blobel GA, Weiss MJ. An abundant erythroid protein that stabilizes free α-haemoglobin Nature. 417: 758-763. PMID 12066189 DOI: 10.1038/nature00803  1
2002 Hong W, Kim AY, Ky S, Rakowski C, Seo SB, Chakravarti D, Atchison M, Blobel GA. Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1 Molecular and Cellular Biology. 22: 3729-3743. PMID 11997509 DOI: 10.1128/MCB.22.11.3729-3743.2002  1
2002 Blobel GA. CBP and p300: Versatile coregulators with important roles in hematopoietic gene expression Journal of Leukocyte Biology. 71: 545-556. PMID 11927640  1
2001 Chen CJ, Deng Z, Kim AY, Blobel GA, Lieberman PM. Stimulation of CREB binding protein nucleosomal histone acetyltransferase activity by a class of transcriptional activators Molecular and Cellular Biology. 21: 476-487. PMID 11134336 DOI: 10.1128/MCB.21.2.476-487.2001  1
2001 Hung HL, Kim AY, Hong W, Rakowski C, Blobel GA. Stimulation of NF-E2 DNA Binding by CREB-binding Protein (CBP)-mediated Acetylation Journal of Biological Chemistry. 276: 10715-10721. DOI: 10.1074/jbc.M007846200  1
2000 Blobel GA. CREB-binding protein and p300: Molecular integrators of hematopoietic transcription Blood. 95: 745-755. PMID 10648382  1
1999 Gregory T, Yu C, Ma A, Orkin SH, Blobel GA, Weiss MJ. GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-x(L) expression Blood. 94: 87-96. PMID 10381501  1
1999 Hung HL, Lau J, Kim AY, Weiss MJ, Blobel GA. CREB-Binding protein acetylates hematopoietic transcription factor GATA- 1 at functionally important sites Molecular and Cellular Biology. 19: 3496-3505. PMID 10207073  1
1998 Blobel GA, Nakajima T, Eckner R, Montminy M, Orkin SH. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation Proceedings of the National Academy of Sciences of the United States of America. 95: 2061-2066. PMID 9482838 DOI: 10.1073/pnas.95.5.2061  1
1996 Blobel GA, Orkin SH. Estrogen-induced apoptosis by inhibition of the erythroid transcription factor GATA-1 Molecular and Cellular Biology. 16: 1687-1694. PMID 8657144  1
1995 Blobel GA, Simon MC, Orkin SH. Rescue of GATA-1-deficient embryonic stem cells by heterologous GATA- binding proteins Molecular and Cellular Biology. 15: 626-633. PMID 7823931  1
1995 Blobel GA, Sieff CA, Orkin SH. Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor Molecular and Cellular Biology. 15: 3147-3153. PMID 7760810  1
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