Robert W. Doms - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Virology Biology, Cell Biology, Microbiology Biology

227 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, ... ... Doms RW, et al. Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247400 DOI: 10.1073/pnas.1606636113  1
2016 Riblett AM, Doms RW. Making Bunyaviruses Talk: Interrogation Tactics to Identify Host Factors Required for Infection. Viruses. 8. PMID 27187446 DOI: 10.3390/v8050130  1
2016 Parker ZF, Rux AH, Riblett AM, Lee FH, Rauova L, Cines DB, Poncz M, Sachais BS, Doms RW. Platelet-Factor 4 (PF4) inhibits and enhances HIV-1 infection in a concentration-dependent manner by modulating viral attachment. Aids Research and Human Retroviruses. PMID 26847431 DOI: 10.1089/AID.2015.0344  1
2016 Doms RW. Basic Concepts: A Step-by-Step Guide to Viral Infection Viral Pathogenesis: From Basics to Systems Biology: Third Edition. 29-40. DOI: 10.1016/B978-0-12-800964-2.00003-3  1
2015 Riblett AM, Blomen VA, Jae LT, Altamura LA, Doms RW, Brummelkamp TR, Wojcechowskyj JA. A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection. Journal of Virology. 90: 1414-23. PMID 26581979 DOI: 10.1128/JVI.02055-15  1
2015 Zhang H, Fu H, Luallen RJ, Liu B, Lee FH, Doms RW, Geng Y. Antibodies elicited by yeast glycoproteins recognize HIV-1 virions and potently neutralize virions with high mannose N-glycans. Vaccine. 33: 5140-7. PMID 26277072 DOI: 10.1016/j.vaccine.2015.08.012  1
2014 Petersen J, Drake MJ, Bruce EA, Riblett AM, Didigu CA, Wilen CB, Malani N, Male F, Lee FH, Bushman FD, Cherry S, Doms RW, Bates P, Briley K. The major cellular sterol regulatory pathway is required for Andes virus infection. Plos Pathogens. 10: e1003911. PMID 24516383 DOI: 10.1371/journal.ppat.1003911  1
2014 Didigu CA, Wilen CB, Wang J, Duong J, Secreto AJ, Danet-Desnoyers GA, Riley JL, Gregory PD, June CH, Holmes MC, Doms RW. Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection. Blood. 123: 61-9. PMID 24162716 DOI: 10.1182/blood-2013-08-521229  1
2013 Wojcechowskyj JA, Didigu CA, Lee JY, Parrish NF, Sinha R, Hahn BH, Bushman FD, Jensen ST, Seeholzer SH, Doms RW. Quantitative phosphoproteomics reveals extensive cellular reprogramming during HIV-1 entry. Cell Host & Microbe. 13: 613-23. PMID 23684312 DOI: 10.1016/j.chom.2013.04.011  1
2013 Parrish NF, Gao F, Li H, Giorgi EE, Barbian HJ, Parrish EH, Zajic L, Iyer SS, Decker JM, Kumar A, Hora B, Berg A, Cai F, Hopper J, Denny TN, ... ... Doms RW, et al. Phenotypic properties of transmitted founder HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 110: 6626-33. PMID 23542380 DOI: 10.1073/pnas.1304288110  1
2013 Parker ZF, Iyer SS, Wilen CB, Parrish NF, Chikere KC, Lee FH, Didigu CA, Berro R, Klasse PJ, Lee B, Moore JP, Shaw GM, Hahn BH, Doms RW. Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5. Journal of Virology. 87: 2401-11. PMID 23269796 DOI: 10.1128/JVI.02964-12  0.32
2012 Richardson MW, Jadlowsky J, Didigu CA, Doms RW, Riley JL. Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 189: 3815-21. PMID 22988032 DOI: 10.4049/jimmunol.1201431  1
2012 Wilen CB, Tilton JC, Doms RW. HIV: cell binding and entry. Cold Spring Harbor Perspectives in Medicine. 2. PMID 22908191 DOI: 10.1101/cshperspect.a006866  1
2012 Parrish NF, Wilen CB, Banks LB, Iyer SS, Pfaff JM, Salazar-Gonzalez JF, Salazar MG, Decker JM, Parrish EH, Berg A, Hopper J, Hora B, Kumar A, Mahlokozera T, Yuan S, ... ... Doms RW, et al. Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7 Plos Pathogens. 8. PMID 22693444 DOI: 10.1371/journal.ppat.1002686  1
2012 Didigu CA, Doms RW. Novel approaches to inhibit HIV entry. Viruses. 4: 309-24. PMID 22470838 DOI: 10.3390/v4020309  1
2012 Wilen CB, Tilton JC, Doms RW. Molecular mechanisms of HIV entry. Advances in Experimental Medicine and Biology. 726: 223-42. PMID 22297516 DOI: 10.1007/978-1-4614-0980-9_10  1
2012 Higa MM, Petersen J, Hooper J, Doms RW. Efficient production of Hantaan and Puumala pseudovirions for viral tropism and neutralization studies. Virology. 423: 134-42. PMID 22209230 DOI: 10.1016/j.virol.2011.08.012  1
2011 Wojcechowskyj JA, Lee JY, Seeholzer SH, Doms RW. Quantitative phosphoproteomics of CXCL12 (SDF-1) signaling. Plos One. 6: e24918. PMID 21949786 DOI: 10.1371/journal.pone.0024918  1
2011 Jiang C, Parrish NF, Wilen CB, Li H, Chen Y, Pavlicek JW, Berg A, Lu X, Song H, Tilton JC, Pfaff JM, Henning EA, Decker JM, Moody MA, Drinker MS, ... ... Doms RW, et al. Primary infection by a human immunodeficiency virus with atypical coreceptor tropism. Journal of Virology. 85: 10669-81. PMID 21835785 DOI: 10.1128/JVI.05249-11  1
2011 Wilen CB, Parrish NF, Pfaff JM, Decker JM, Henning EA, Haim H, Petersen JE, Wojcechowskyj JA, Sodroski J, Haynes BF, Montefiori DC, Tilton JC, Shaw GM, Hahn BH, Doms RW. Phenotypic and immunologic comparison of clade B transmitted/founder and chronic HIV-1 envelope glycoproteins. Journal of Virology. 85: 8514-27. PMID 21715507 DOI: 10.1128/JVI.00736-11  1
2011 Doms RW. Fusing HIV and chemokine receptors. Journal of Immunology (Baltimore, Md. : 1950). 186: 6073-5. PMID 21597039 DOI: 10.4049/jimmunol.1100982  1
2011 Wilen CB, Wang J, Tilton JC, Miller JC, Kim KA, Rebar EJ, Sherrill-Mix SA, Patro SC, Secreto AJ, Jordan AP, Lee G, Kahn J, Aye PP, Bunnell BA, Lackner AA, ... ... Doms RW, et al. Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases. Plos Pathogens. 7: e1002020. PMID 21533216 DOI: 10.1371/journal.ppat.1002020  1
2011 Agrawal-Gamse C, Luallen RJ, Liu B, Fu H, Lee FH, Geng Y, Doms RW. Yeast-elicited cross-reactive antibodies to HIV Env glycans efficiently neutralize virions expressing exclusively high-mannose N-linked glycans. Journal of Virology. 85: 470-80. PMID 20962094 DOI: 10.1128/JVI.01349-10  1
2010 Wojcechowskyj JA, Doms RW. A Potent, Broad-Spectrum Antiviral Agent that Targets Viral Membranes. Viruses. 2: 1106-9. PMID 21994673 DOI: 10.3390/v2051106  1
2010 Filone CM, Hanna SL, Caino MC, Bambina S, Doms RW, Cherry S. Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon. Plos One. 5: e15483. PMID 21124804 DOI: 10.1371/journal.pone.0015483  1
2010 Doms RW. Immunology. Prime, boost, and broaden. Science (New York, N.Y.). 329: 1021-2. PMID 20798304 DOI: 10.1126/science.1195116  1
2010 Tilton JC, Wilen CB, Didigu CA, Sinha R, Harrison JE, Agrawal-Gamse C, Henning EA, Bushman FD, Martin JN, Deeks SG, Doms RW. A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5. Journal of Virology. 84: 10863-76. PMID 20702642 DOI: 10.1128/JVI.01109-10  1
2010 Pfaff JM, Wilen CB, Harrison JE, Demarest JF, Lee B, Doms RW, Tilton JC. HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells. Journal of Virology. 84: 6505-14. PMID 20410277 DOI: 10.1128/JVI.00374-10  1
2010 Tilton JC, Amrine-Madsen H, Miamidian JL, Kitrinos KM, Pfaff J, Demarest JF, Ray N, Jeffrey JL, Labranche CC, Doms RW. HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry. Aids Research and Human Retroviruses. 26: 13-24. PMID 20055594 DOI: 10.1089/aid.2009.0132  1
2010 Luallen RJ, Agrawal-Gamse C, Fu H, Smith DF, Doms RW, Geng Y. Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strains. Glycobiology. 20: 280-6. PMID 19920089 DOI: 10.1093/glycob/cwp184  1
2010 Tilton JC, Doms RW. Entry inhibitors in the treatment of HIV-1 infection. Antiviral Research. 85: 91-100. PMID 19683546 DOI: 10.1016/j.antiviral.2009.07.022  1
2009 Agrawal-Gamse C, Lee FH, Haggarty B, Jordan AP, Yi Y, Lee B, Collman RG, Hoxie JA, Doms RW, Laakso MM. Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4. Journal of Virology. 83: 11005-15. PMID 19692476 DOI: 10.1128/JVI.01238-09  1
2009 Pugach P, Ray N, Klasse PJ, Ketas TJ, Michael E, Doms RW, Lee B, Moore JP. Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities. Virology. 387: 296-302. PMID 19303620 DOI: 10.1016/j.virol.2009.02.044  1
2009 Luallen RJ, Fu H, Agrawal-Gamse C, Mboudjeka I, Huang W, Lee FH, Wang LX, Doms RW, Geng Y. A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN. Journal of Virology. 83: 4861-70. PMID 19264785 DOI: 10.1128/JVI.02537-08  1
2009 Wu L, Zhou T, Yang ZY, Svehla K, O'Dell S, Louder MK, Xu L, Mascola JR, Burton DR, Hoxie JA, Doms RW, Kwong PD, Nabel GJ. Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain. Journal of Virology. 83: 5077-86. PMID 19264769 DOI: 10.1128/JVI.02600-08  1
2009 Ray N, Blackburn LA, Doms RW. HR-2 mutations in human immunodeficiency virus type 1 gp41 restore fusion kinetics delayed by HR-1 mutations that cause clinical resistance to enfuvirtide. Journal of Virology. 83: 2989-95. PMID 19153234 DOI: 10.1128/JVI.02496-08  1
2008 Harrison JE, Lynch JB, Sierra LJ, Blackburn LA, Ray N, Collman RG, Doms RW. Baseline resistance of primary human immunodeficiency virus type 1 strains to the CXCR4 inhibitor AMD3100. Journal of Virology. 82: 11695-704. PMID 18799588 DOI: 10.1128/JVI.01303-08  1
2008 Luallen RJ, Lin J, Fu H, Cai KK, Agrawal C, Mboudjeka I, Lee FH, Montefiori D, Smith DF, Doms RW, Geng Y. An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies. Journal of Virology. 82: 6447-57. PMID 18434410 DOI: 10.1128/JVI.00412-08  1
2008 Selvarajah S, Puffer BA, Lee FH, Zhu P, Li Y, Wyatt R, Roux KH, Doms RW, Burton DR. Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. Aids Research and Human Retroviruses. 24: 301-14. PMID 18284327 DOI: 10.1089/aid.2007.0158  1
2008 Dey AK, David KB, Ray N, Ketas TJ, Klasse PJ, Doms RW, Moore JP. N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus. Virology. 372: 187-200. PMID 18031785 DOI: 10.1016/j.virol.2007.10.018  1
2007 Laakso MM, Lee FH, Haggarty B, Agrawal C, Nolan KM, Biscone M, Romano J, Jordan AP, Leslie GJ, Meissner EG, Su L, Hoxie JA, Doms RW. V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies. Plos Pathogens. 3: e117. PMID 17722977 DOI: 10.1371/journal.ppat.0030117  1
2007 Marzi A, Mitchell DA, Chaipan C, Fisch T, Doms RW, Carrington M, Desrosiers RC, Pöhlmann S. Modulation of HIV and SIV neutralization sensitivity by DC-SIGN and mannose-binding lectin. Virology. 368: 322-30. PMID 17659761 DOI: 10.1016/j.virol.2007.07.004  1
2007 Lin G, Bertolotti-Ciarlet A, Haggarty B, Romano J, Nolan KM, Leslie GJ, Jordan AP, Huang CC, Kwong PD, Doms RW, Hoxie JA. Replication-competent variants of human immunodeficiency virus type 2 lacking the V3 loop exhibit resistance to chemokine receptor antagonists. Journal of Virology. 81: 9956-66. PMID 17609282 DOI: 10.1128/JVI.00385-07  1
2007 Dhillon AK, Donners H, Pantophlet R, Johnson WE, Decker JM, Shaw GM, Lee FH, Richman DD, Doms RW, Vanham G, Burton DR. Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors. Journal of Virology. 81: 6548-62. PMID 17409160 DOI: 10.1128/JVI.02749-06  1
2007 Altamura LA, Bertolotti-Ciarlet A, Teigler J, Paragas J, Schmaljohn CS, Doms RW. Identification of a novel C-terminal cleavage of Crimean-Congo hemorrhagic fever virus PreGN that leads to generation of an NSM protein. Journal of Virology. 81: 6632-42. PMID 17409136 DOI: 10.1128/JVI.02730-06  1
2007 Ray N, Harrison JE, Blackburn LA, Martin JN, Deeks SG, Doms RW. Clinical resistance to enfuvirtide does not affect susceptibility of human immunodeficiency virus type 1 to other classes of entry inhibitors. Journal of Virology. 81: 3240-50. PMID 17251281 DOI: 10.1128/JVI.02413-06  1
2007 Pöhlmann S, Münch J, Aziz S, Reeves JD, Otto C, Leslie GJ, Hofmann H, Puffer BA, Baribaud F, Marzi A, Gramberg T, Chen Z, Stolte N, Haaft PT, Heeney JL, ... ... Doms RW, et al. A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo. Virology. 360: 275-85. PMID 17126374 DOI: 10.1016/j.virol.2006.10.020  1
2007 Sánchez MD, Pierson TC, Degrace MM, Mattei LM, Hanna SL, Del Piero F, Doms RW. The neutralizing antibody response against West Nile virus in naturally infected horses. Virology. 359: 336-48. PMID 17055550 DOI: 10.1016/j.virol.2006.08.047  1
2006 Gallo SA, Reeves JD, Garg H, Foley B, Doms RW, Blumenthal R. Kinetic studies of HIV-1 and HIV-2 envelope glycoprotein-mediated fusion. Retrovirology. 3: 90. PMID 17144914 DOI: 10.1186/1742-4690-3-90  1
2006 Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, et al. A plea for justice for jailed medical workers. Science (New York, N.Y.). 314: 924-5. PMID 17062652 DOI: 10.1126/science.1136578  1
2006 Davis CW, Mattei LM, Nguyen HY, Ansarah-Sobrinho C, Doms RW, Pierson TC. The location of asparagine-linked glycans on West Nile virions controls their interactions with CD209 (dendritic cell-specific ICAM-3 grabbing nonintegrin). The Journal of Biological Chemistry. 281: 37183-94. PMID 17001080 DOI: 10.1074/jbc.M605429200  1
2006 Filone CM, Heise M, Doms RW, Bertolotti-Ciarlet A. Development and characterization of a Rift Valley fever virus cell-cell fusion assay using alphavirus replicon vectors. Virology. 356: 155-64. PMID 16945399 DOI: 10.1016/j.virol.2006.07.035  1
2006 Morais VA, Brito C, Pijak DS, Crystal AS, Fortna RR, Li T, Wong PC, Doms RW, Costa J. N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53. Biochimica Et Biophysica Acta. 1762: 802-10. PMID 16938437 DOI: 10.1016/j.bbadis.2006.06.018  1
2006 Biscone MJ, Miamidian JL, Muchiri JM, Baik SS, Lee FH, Doms RW, Reeves JD. Functional impact of HIV coreceptor-binding site mutations. Virology. 351: 226-36. PMID 16631222 DOI: 10.1016/j.virol.2006.03.017  1
2006 Ray N, Doms RW. HIV-1 coreceptors and their inhibitors Current Topics in Microbiology and Immunology. 303: 97-120. PMID 16570858 DOI: 10.1007/3-540-33247-2_12  1
2006 Davis CW, Nguyen HY, Hanna SL, Sánchez MD, Doms RW, Pierson TC. West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection. Journal of Virology. 80: 1290-301. PMID 16415006 DOI: 10.1128/JVI.80.3.1290-1301.2006  1
2006 Pierson TC, Sánchez MD, Puffer BA, Ahmed AA, Geiss BJ, Valentine LE, Altamura LA, Diamond MS, Doms RW. A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection. Virology. 346: 53-65. PMID 16325883 DOI: 10.1016/j.virol.2005.10.030  1
2006 Haskell CA, Horuk R, Liang M, Rosser M, Dunning L, Islam I, Kremer L, Gutiérrez J, Marquez G, Martinez-A C, Biscone MJ, Doms RW, Ribeiro S. Identification and characterization of a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8. Molecular Pharmacology. 69: 309-16. PMID 16221874 DOI: 10.1124/mol.105.014779  1
2005 Ahmed AA, McFalls JM, Hoffmann C, Filone CM, Stewart SM, Paragas J, Khodjaev S, Shermukhamedova D, Schmaljohn CS, Doms RW, Bertolotti-Ciarlet A. Presence of broadly reactive and group-specific neutralizing epitopes on newly described isolates of Crimean-Congo hemorrhagic fever virus. The Journal of General Virology. 86: 3327-36. PMID 16298978 DOI: 10.1099/vir.0.81175-0  1
2005 Hanna SL, Pierson TC, Sanchez MD, Ahmed AA, Murtadha MM, Doms RW. N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity. Journal of Virology. 79: 13262-74. PMID 16227249 DOI: 10.1128/JVI.79.21.13262-13274.2005  1
2005 Selvarajah S, Puffer B, Pantophlet R, Law M, Doms RW, Burton DR. Comparing antigenicity and immunogenicity of engineered gp120. Journal of Virology. 79: 12148-63. PMID 16160142 DOI: 10.1128/JVI.79.19.12148-12163.2005  1
2005 Whitby K, Pierson TC, Geiss B, Lane K, Engle M, Zhou Y, Doms RW, Diamond MS. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. Journal of Virology. 79: 8698-706. PMID 15994763 DOI: 10.1128/JVI.79.14.8698-8706.2005  1
2005 Sánchez MD, Pierson TC, McAllister D, Hanna SL, Puffer BA, Valentine LE, Murtadha MM, Hoxie JA, Doms RW. Characterization of neutralizing antibodies to West Nile virus. Virology. 336: 70-82. PMID 15866072 DOI: 10.1016/j.virol.2005.02.020  1
2005 Bertolotti-Ciarlet A, Smith J, Strecker K, Paragas J, Altamura LA, McFalls JM, Frias-Stäheli N, García-Sastre A, Schmaljohn CS, Doms RW. Cellular localization and antigenic characterization of crimean-congo hemorrhagic fever virus glycoproteins. Journal of Virology. 79: 6152-61. PMID 15858000 DOI: 10.1128/JVI.79.10.6152-6161.2005  1
2005 Reeves JD, Lee FH, Miamidian JL, Jabara CB, Juntilla MM, Doms RW. Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization. Journal of Virology. 79: 4991-9. PMID 15795284 DOI: 10.1128/JVI.79.8.4991-4999.2005  1
2005 Pierson TC, Diamond MS, Ahmed AA, Valentine LE, Davis CW, Samuel MA, Hanna SL, Puffer BA, Doms RW. An infectious West Nile virus that expresses a GFP reporter gene. Virology. 334: 28-40. PMID 15749120 DOI: 10.1016/j.virol.2005.01.021  1
2005 Lee EB, Zhang B, Liu K, Greenbaum EA, Doms RW, Trojanowski JQ, Lee VM. BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo. The Journal of Cell Biology. 168: 291-302. PMID 15642747 DOI: 10.1083/jcb.200407070  1
2004 Doms RW. Unwelcome guests with master keys: how HIV enters cells and how it can be stopped. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 12: 100-3. PMID 15516706  1
2004 Puffer BA, Altamura LA, Pierson TC, Doms RW. Determinants within gp120 and gp41 contribute to CD4 independence of SIV Envs. Virology. 327: 16-25. PMID 15327894 DOI: 10.1016/j.virol.2004.03.016  1
2004 Doms RW. Viral entry denied. The New England Journal of Medicine. 351: 743-4. PMID 15317885 DOI: 10.1056/NEJMp048058  1
2004 Pierson TC, Doms RW, Pöhlmann S. Prospects of HIV-1 entry inhibitors as novel therapeutics. Reviews in Medical Virology. 14: 255-70. PMID 15248253 DOI: 10.1002/rmv.435  1
2004 Swanson CM, Puffer BA, Ahmad KM, Doms RW, Malim MH. Retroviral mRNA nuclear export elements regulate protein function and virion assembly. The Embo Journal. 23: 2632-40. PMID 15201866 DOI: 10.1038/sj.emboj.7600270  1
2004 Yuste E, Reeves JD, Doms RW, Desrosiers RC. Modulation of Env content in virions of simian immunodeficiency virus: correlation with cell surface expression and virion infectivity. Journal of Virology. 78: 6775-85. PMID 15194752 DOI: 10.1128/JVI.78.13.6775-6785.2004  1
2004 Reeves JD, Miamidian JL, Biscone MJ, Lee FH, Ahmad N, Pierson TC, Doms RW. Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity. Journal of Virology. 78: 5476-85. PMID 15113926 DOI: 10.1128/JVI.78.10.5476-5485.2004  1
2004 Davis CW, Doms RW. HIV transmission: closing all the doors. The Journal of Experimental Medicine. 199: 1037-40. PMID 15078894 DOI: 10.1084/jem.20040426  1
2004 Crystal AS, Morais VA, Fortna RR, Carlin D, Pierson TC, Wilson CA, Lee VM, Doms RW. Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. Biochemistry. 43: 3555-63. PMID 15035625 DOI: 10.1021/bi0361214  1
2004 Pöhlmann S, Davis C, Meister S, Leslie GJ, Otto C, Reeves JD, Puffer BA, Papkalla A, Krumbiegel M, Marzi A, Lorenz S, Münch J, Doms RW, Kirchhoff F. Amino acid 324 in the simian immunodeficiency virus SIVmac V3 loop can confer CD4 independence and modulate the interaction with CCR5 and alternative coreceptors. Journal of Virology. 78: 3223-32. PMID 15016843 DOI: 10.1128/JVI.78.7.3223-3232.2004  1
2004 Burton DR, Desrosiers RC, Doms RW, Koff WC, Kwong PD, Moore JP, Nabel GJ, Sodroski J, Wilson IA, Wyatt RT. HIV vaccine design and the neutralizing antibody problem. Nature Immunology. 5: 233-6. PMID 14985706 DOI: 10.1038/ni0304-233  1
2004 Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science (New York, N.Y.). 303: 316. PMID 14726576 DOI: 10.1126/science.1094620  1
2004 Fortna RR, Crystal AS, Morais VA, Pijak DS, Lee VM, Doms RW. Membrane topology and nicastrin-enhanced endoproteolysis of APH-1, a component of the gamma-secretase complex. The Journal of Biological Chemistry. 279: 3685-93. PMID 14593096 DOI: 10.1074/jbc.M310505200  1
2003 Veazey RS, Klasse PJ, Ketas TJ, Reeves JD, Piatak M, Kunstman K, Kuhmann SE, Marx PA, Lifson JD, Dufour J, Mefford M, Pandrea I, Wolinsky SM, Doms RW, DeMartino JA, et al. Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection. The Journal of Experimental Medicine. 198: 1551-62. PMID 14623909 DOI: 10.1084/jem.20031266  1
2003 Vödrös D, Thorstensson R, Doms RW, Fenyö EM, Reeves JD. Evolution of coreceptor use and CD4-independence in envelope clones derived from SIVsm-infected macaques. Virology. 316: 17-28. PMID 14599787 DOI: 10.1016/S0042-6822(03)00579-8  1
2003 Wilson CA, Doms RW, Lee VM. Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production. Journal of Neuroscience Research. 74: 361-9. PMID 14598312 DOI: 10.1002/jnr.10776  1
2003 Otto C, Puffer BA, Pöhlmann S, Doms RW, Kirchhoff F. Mutations in the C3 region of human and simian immunodeficiency virus envelope have differential effects on viral infectivity, replication, and CD4-dependency. Virology. 315: 292-302. PMID 14585332 DOI: 10.1016/S0042-6822(03)00513-0  1
2003 Moore JP, Doms RW. The entry of entry inhibitors: a fusion of science and medicine. Proceedings of the National Academy of Sciences of the United States of America. 100: 10598-602. PMID 12960367 DOI: 10.1073/pnas.1932511100  1
2003 Pierson TC, Doms RW. HIV-1 entry and its inhibition. Current Topics in Microbiology and Immunology. 281: 1-27. PMID 12932074  1
2003 Morais VA, Crystal AS, Pijak DS, Carlin D, Costa J, Lee VM, Doms RW. The transmembrane domain region of nicastrin mediates direct interactions with APH-1 and the gamma-secretase complex. The Journal of Biological Chemistry. 278: 43284-91. PMID 12917438 DOI: 10.1074/jbc.M305685200  1
2003 Chalasani SH, Baribaud F, Coughlan CM, Sunshine MJ, Lee VM, Doms RW, Littman DR, Raper JA. The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4601-12. PMID 12805300  1
2003 Dehghani H, Puffer BA, Doms RW, Hirsch VM. Unique pattern of convergent envelope evolution in simian immunodeficiency virus-infected rapid progressor macaques: association with CD4-independent usage of CCR5. Journal of Virology. 77: 6405-18. PMID 12743298 DOI: 10.1128/JVI.77.11.6405-6418.2003  1
2003 Crystal AS, Morais VA, Pierson TC, Pijak DS, Carlin D, Lee VM, Doms RW. Membrane topology of gamma-secretase component PEN-2. The Journal of Biological Chemistry. 278: 20117-23. PMID 12639958 DOI: 10.1074/jbc.M213107200  1
2003 Huse JT, Byant D, Yang Y, Pijak DS, D'Souza I, Lah JJ, Lee VM, Doms RW, Cook DG. Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation. The Journal of Biological Chemistry. 278: 17141-9. PMID 12551920 DOI: 10.1074/jbc.M213303200  1
2003 Pierson TC, Doms RW. HIV-1 entry inhibitors: new targets, novel therapies. Immunology Letters. 85: 113-8. PMID 12527216 DOI: 10.1016/S0165-2478(02)00235-3  1
2003 Simmons G, Reeves JD, Grogan CC, Vandenberghe LH, Baribaud F, Whitbeck JC, Burke E, Buchmeier MJ, Soilleux EJ, Riley JL, Doms RW, Bates P, Pöhlmann S. DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells. Virology. 305: 115-23. PMID 12504546 DOI: 10.1006/viro.2002.1730  1
2003 Lin G, Simmons G, Pöhlmann S, Baribaud F, Ni H, Leslie GJ, Haggarty BS, Bates P, Weissman D, Hoxie JA, Doms RW. Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR. Journal of Virology. 77: 1337-46. PMID 12502850 DOI: 10.1128/JVI.77.2.1337-1346.2003  1
2003 Lin G, Baribaud F, Romano J, Doms RW, Hoxie JA. Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins. Journal of Virology. 77: 931-42. PMID 12502809 DOI: 10.1128/JVI.77.2.931-942.2003  1
2003 Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM. Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons. The Journal of Biological Chemistry. 278: 4458-66. PMID 12480937 DOI: 10.1074/jbc.M210105200  1
2003 Blanpain C, Doranz BJ, Bondue A, Govaerts C, De Leener A, Vassart G, Doms RW, Proudfoot A, Parmentier M. The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle. The Journal of Biological Chemistry. 278: 5179-87. PMID 12466283 DOI: 10.1074/jbc.M205684200  1
2003 Reeves JD, Doms RW. The Role of Chemokine Receptors in HIV Infection of Host Cells Handbook of Cell Signaling. 1: 191-196. DOI: 10.1016/B978-012124546-7/50393-4  1
2002 Pöhlmann S, Doms RW. Evaluation of current approaches to inhibit HIV entry Current Drug Targets - Infectious Disorders. 2: 9-16. PMID 12462149  1
2002 Reeves JD, Gallo SA, Ahmad N, Miamidian JL, Harvey PE, Sharron M, Pohlmann S, Sfakianos JN, Derdeyn CA, Blumenthal R, Hunter E, Doms RW. Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proceedings of the National Academy of Sciences of the United States of America. 99: 16249-54. PMID 12444251 DOI: 10.1073/pnas.252469399  1
2002 Turville SG, Cameron PU, Handley A, Lin G, Pöhlmann S, Doms RW, Cunningham AL. Diversity of receptors binding HIV on dendritic cell subsets. Nature Immunology. 3: 975-83. PMID 12352970 DOI: 10.1038/ni841  1
2002 Biscone MJ, Pierson TC, Doms RW. Opportunities and challenges in targeting HIV entry. Current Opinion in Pharmacology. 2: 529-33. PMID 12324254 DOI: 10.1016/S1471-4892(02)00200-X  1
2002 Baribaud F, Doms RW, Pöhlmann S. The role of DC-SIGN and DC-SIGNR in HIV and Ebola virus infection: can potential therapeutics block virus transmission and dissemination? Expert Opinion On Therapeutic Targets. 6: 423-31. PMID 12223058 DOI: 10.1517/14728222.6.4.423  1
2002 Baribaud F, Pöhlmann S, Leslie G, Mortari F, Doms RW. Quantitative expression and virus transmission analysis of DC-SIGN on monocyte-derived dendritic cells. Journal of Virology. 76: 9135-42. PMID 12186897 DOI: 10.1128/JVI.76.18.9135-9142.2002  1
2002 Wilson CA, Doms RW, Zheng H, Lee VM. Presenilins are not required for A beta 42 production in the early secretory pathway. Nature Neuroscience. 5: 849-55. PMID 12145638 DOI: 10.1038/nn898  1
2002 Goldsmith MA, Doms RW. HIV entry: are all receptors created equal? Nature Immunology. 3: 709-10. PMID 12089511 DOI: 10.1038/ni819  1
2002 Reeves JD, Doms RW. Human immunodeficiency virus type 2. The Journal of General Virology. 83: 1253-65. PMID 12029140 DOI: 10.1099/0022-1317-83-6-1253  1
2002 Shattock RJ, Doms RW. AIDS models: microbicides could learn from vaccines. Nature Medicine. 8: 425. PMID 11984565 DOI: 10.1038/nm0502-425  1
2002 Münch J, Ständker L, Pöhlmann S, Baribaud F, Papkalla A, Rosorius O, Stauber R, Sass G, Heveker N, Adermann K, Escher S, Klüver E, Doms RW, Forssmann WG, Kirchhoff F. Hemofiltrate CC chemokine 1[9-74] causes effective internalization of CCR5 and is a potent inhibitor of R5-tropic human immunodeficiency virus type 1 strains in primary T cells and macrophages. Antimicrobial Agents and Chemotherapy. 46: 982-90. PMID 11897579 DOI: 10.1128/AAC.46.4.982-990.2002  1
2002 Soilleux EJ, Morris LS, Leslie G, Chehimi J, Luo Q, Levroney E, Trowsdale J, Montaner LJ, Doms RW, Weissman D, Coleman N, Lee B. Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro. Journal of Leukocyte Biology. 71: 445-57. PMID 11867682  1
2002 Liu K, Doms RW, Lee VM. Glu11 site cleavage and N-terminally truncated A beta production upon BACE overexpression. Biochemistry. 41: 3128-36. PMID 11863452 DOI: 10.1021/bi015800g  1
2002 Edwards TG, Wyss S, Reeves JD, Zolla-Pazner S, Hoxie JA, Doms RW, Baribaud F. Truncation of the cytoplasmic domain induces exposure of conserved regions in the ectodomain of human immunodeficiency virus type 1 envelope protein. Journal of Virology. 76: 2683-91. PMID 11861835 DOI: 10.1128/JVI.76.6.2683-2691.2002  1
2002 Puffer BA, Pöhlmann S, Edinger AL, Carlin D, Sanchez MD, Reitter J, Watry DD, Fox HS, Desrosiers RC, Doms RW. CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity. Journal of Virology. 76: 2595-605. PMID 11861825 DOI: 10.1128/JVI.76.6.2595-2605.2002  1
2002 Huse JT, Liu K, Pijak DS, Carlin D, Lee VM, Doms RW. Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain. The Journal of Biological Chemistry. 277: 16278-84. PMID 11847218 DOI: 10.1074/jbc.M111141200  1
2002 Johnson WE, Morgan J, Reitter J, Puffer BA, Czajak S, Doms RW, Desrosiers RC. A replication-competent, neutralization-sensitive variant of simian immunodeficiency virus lacking 100 amino acids of envelope. Journal of Virology. 76: 2075-86. PMID 11836385 DOI: 10.1128/jvi.76.5.2075-2086.2002  1
2002 Jameson B, Baribaud F, Pöhlmann S, Ghavimi D, Mortari F, Doms RW, Iwasaki A. Expression of DC-SIGN by dendritic cells of intestinal and genital mucosae in humans and rhesus macaques. Journal of Virology. 76: 1866-75. PMID 11799181 DOI: 10.1128/JVI.76.4.1866-1875.2002  1
2001 Soilleux EJ, Morris LS, Lee B, Pöhlmann S, Trowsdale J, Doms RW, Coleman N. Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV. The Journal of Pathology. 195: 586-92. PMID 11745695 DOI: 10.1002/path.1026  1
2001 Pöhlmann S, Baribaud F, Doms RW. DC-SIGN and DC-SIGNR: Helping hands for HIV Trends in Immunology. 22: 643-646. PMID 11738974 DOI: 10.1016/S1471-4906(01)02081-6  1
2001 Lee B, Leslie G, Soilleux E, O'Doherty U, Baik S, Levroney E, Flummerfelt K, Swiggard W, Coleman N, Malim M, Doms RW. cis expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor Journal of Virology. 75: 12028-12038. PMID 11711593 DOI: 10.1128/JVI.75.24.12028-12038.2001  1
2001 Lin G, Lee B, Haggarty BS, Doms RW, Hoxie JA. CD4-independent use of Rhesus CCR5 by human immunodeficiency virus Type 2 implicates an electrostatic interaction between the CCR5 N terminus and the gp120 C4 domain. Journal of Virology. 75: 10766-78. PMID 11602718 DOI: 10.1128/JVI.75.22.10766-10778.2001  1
2001 Pöhlmann S, Leslie GJ, Edwards TG, Macfarlan T, Reeves JD, Hiebenthal-Millow K, Kirchhoff F, Baribaud F, Doms RW. DC-SIGN interactions with human immunodeficiency virus: virus binding and transfer are dissociable functions. Journal of Virology. 75: 10523-6. PMID 11581425 DOI: 10.1128/JVI.75.21.10523-10526.2001  1
2001 Baribaud F, Edwards TG, Sharron M, Brelot A, Heveker N, Price K, Mortari F, Alizon M, Tsang M, Doms RW. Antigenically distinct conformations of CXCR4. Journal of Virology. 75: 8957-67. PMID 11533159 DOI: 10.1128/JVI.75.19.8957-8967.2001  1
2001 Baribaud F, Doms RW. The impact of chemokine receptor conformational heterogeneity on HIV infection Cellular and Molecular Biology. 47: 653-660. PMID 11502072  1
2001 Baribaud F, Pöhlmann S, Doms RW. The role of DC-SIGN and DC-SIGNR in HIV and SIV attachment, infection, and transmission Virology. 286: 1-6. PMID 11448153 DOI: 10.1006/viro.2001.0975  1
2001 Doms RW. Chemokine receptors and HIV entry Aids. 15. PMID 11403007  1
2001 Doranz BJ, Doms RW, Filion LG, Diaz-Mitoma F, Sitar DS, Sahai J, Baribaud F, Orsini MJ, Benovic JL, Cameron W. Safe use of the CXCR4 inhibitor ALX40-4C in humans Aids Research and Human Retroviruses. 17: 475-486. PMID 11350661 DOI: 10.1089/08892220151126508  1
2001 Edwards TG, Hoffman TL, Baribaud F, Wyss S, LaBranche CC, Romano J, Adkinson J, Sharron M, Hoxie JA, Doms RW. Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein. Journal of Virology. 75: 5230-9. PMID 11333905 DOI: 10.1128/JVI.75.11.5230-5239.2001  1
2001 Pöhlmann S, Baribaud F, Lee B, Leslie GJ, Sanchez MD, Hiebenthal-Millow K, Münch J, Kirchhoff F, Doms RW. DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. Journal of Virology. 75: 4664-72. PMID 11312337 DOI: 10.1128/JVI.75.10.4664-4672.2001  1
2001 Huse JT, Doms RW. Neurotoxic traffic: uncovering the mechanics of amyloid production in Alzheimer's disease. Traffic (Copenhagen, Denmark). 2: 75-81. PMID 11247305 DOI: 10.1034/j.1600-0854.2001.020201.x  1
2001 Pöhlmann S, Soilleux EJ, Baribaud F, Leslie GJ, Morris LS, Trowsdale J, Lee B, Coleman N, Doms RW. DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans. Proceedings of the National Academy of Sciences of the United States of America. 98: 2670-5. PMID 11226297 DOI: 10.1073/pnas.051631398  1
2000 Huse JT, Doms RW. Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease. Molecular Neurobiology. 22: 81-98. PMID 11414282 DOI: 10.1385/MN:22:1-3:081  1
2000 Doms RW, Trono D. The plasma membrane as a combat zone in the HIV battlefield Genes and Development. 14: 2677-2688. PMID 11069884 DOI: 10.1101/gad.833300  1
2000 Moore JP, Doms RW. HIV: Much at stake with kidneys? Journal of the American Society of Nephrology. 11: 2138-2140. PMID 11053492  1
2000 Puffer BA, Sharron M, Coughlan CM, Baribaud F, McManus CM, Lee B, David J, Price K, Horuk R, Tsang M, Doms RW. Expression and coreceptor function of APJ for primate immunodeficiency viruses Virology. 276: 435-444. PMID 11040134 DOI: 10.1006/viro.2000.0557  1
2000 Doms RW. Beyond receptor expression: The influence of receptor conformation, density, and affinity in HIV-1 infection Virology. 276: 229-237. PMID 11040114 DOI: 10.1006/viro.2000.0612  1
2000 Doms RW, Moore JP. HIV-1 membrane fusion: Targets of opportunity Journal of Cell Biology. 151. PMID 11038194  1
2000 Hoffman TL, Canziani G, Jia L, Rucker J, Doms RW. A biosensor assay for studying ligand-membrane receptor interactions: binding of antibodies and HIV-1 Env to chemokine receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 11215-20. PMID 11005830 DOI: 10.1073/pnas.190274097  1
2000 Edinger AL, Ahuja M, Sung T, Baxter KC, Haggarty B, Doms RW, Hoxie JA. Characterization and epitope mapping of neutralizing monoclonal antibodies produced by immunization with oligomeric simian immunodeficiency virus envelope protein Journal of Virology. 74: 7922-7935. PMID 10933700 DOI: 10.1128/JVI.74.17.7922-7935.2000  1
2000 Pierson T, Hoffman TL, Blankson J, Finzi D, Chadwick K, Margolick JB, Buck C, Siliciano JD, Doms RW, Siliciano RF. Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1. Journal of Virology. 74: 7824-33. PMID 10933689 DOI: 10.1128/JVI.74.17.7824-7833.2000  1
2000 Huse JT, Pijak DS, Leslie GJ, Lee VM, Doms RW. Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase. The Journal of Biological Chemistry. 275: 33729-37. PMID 10924510 DOI: 10.1074/jbc.M004175200  1
2000 Sharron M, Pöhlmann S, Price K, Lolis E, Tsang M, Kirchhoff F, Doms RW, Lee B. Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. Blood. 96: 41-9. PMID 10891428  1
2000 McManus CM, Doms RW. Fusion mediated by the HIV-1 envelope protein Sub-Cellular Biochemistry. 34: 457-481. PMID 10808341  1
2000 Pöhlmann S, Lee B, Meister S, Krumbiegel M, Leslie G, Doms RW, Kirchhoff F. Simian immunodeficiency virus utilizes human and sooty mangabey but not rhesus macaque STRL33 for efficient entry. Journal of Virology. 74: 5075-82. PMID 10799581 DOI: 10.1128/JVI.74.11.5075-5082.2000  1
2000 Liu QH, Williams DA, McManus C, Baribaud F, Doms RW, Schols D, De Clercq E, Kotlikoff MI, Collman RG, Freedman BD. HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation Proceedings of the National Academy of Sciences of the United States of America. 97: 4832-4837. PMID 10758170 DOI: 10.1073/pnas.090521697  1
2000 Skovronsky DM, Pijak DS, Doms RW, Lee VM. A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP. Biochemistry. 39: 810-7. PMID 10651647 DOI: 10.1021/bi991728z  1
2000 Skovronsky DM, Moore DB, Milla ME, Doms RW, Lee VM. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network. The Journal of Biological Chemistry. 275: 2568-75. PMID 10644715 DOI: 10.1074/jbc.275.4.2568  1
1999 Doranz BJ, Baik SSW, Doms RW. Use of a gp120 binding assay to dissect the requirements and kinetics of human immunodeficiency virus fusion events Journal of Virology. 73: 10346-10358. PMID 10559353  1
1999 LaBranche CC, Hoffman TL, Romano J, Haggarty BS, Edwards TG, Matthews TJ, Doms RW, Hoxie JA. Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity. Journal of Virology. 73: 10310-9. PMID 10559349  1
1999 Blanpain C, Migeotte I, Lee B, Vakili J, Doranz BJ, Govaerts C, Vassart G, Doms RW, Parmentier M. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood. 94: 1899-905. PMID 10477718  1
1999 Pritsker M, Rucker J, Hoffman TL, Doms RW, Shai Y. Effect of nonpolar substitutions of the conserved Phe11 in the fusion peptide of HIV-1 gp41 on its function, structure, and organization in membranes. Biochemistry. 38: 11359-71. PMID 10471286 DOI: 10.1021/bi990232e  1
1999 Wilson CA, Doms RW, Lee VM. Intracellular APP processing and A beta production in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 58: 787-94. PMID 10446803  1
1999 Liu ZQ, Muhkerjee S, Sahni M, McCormick-Davis C, Leung K, Li Z, Gattone VH, Tian C, Doms RW, Hoffman TL, Raghavan R, Narayan O, Stephens EB. Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques. Virology. 260: 295-307. PMID 10417264 DOI: 10.1006/viro.1999.9812  1
1999 Edinger AL, Clements JE, Doms RW. Chemokine and orphan receptors in HIV-2 and SIV tropism and pathogenesis Virology. 260: 211-221. PMID 10417256 DOI: 10.1006/viro.1999.9819  1
1999 Baik SSW, Doms RW, Doranz BJ. HIV and SIV gp120 binding does not predict coreceptor function Virology. 259: 267-273. PMID 10388651 DOI: 10.1006/viro.1999.9779  1
1999 Blanpain C, Lee B, Vakili J, Doranz BJ, Govaerts C, Migeotte I, Sharron M, Dupriez V, Vassart G, Doms RW, Parmentier M. Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity. The Journal of Biological Chemistry. 274: 18902-8. PMID 10383387 DOI: 10.1074/jbc.274.27.18902  1
1999 Hoffman TL, LaBranche CC, Zhang W, Canziani G, Robinson J, Chaiken I, Hoxie JA, Doms RW. Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 6359-64. PMID 10339592 DOI: 10.1073/pnas.96.11.6359  1
1999 Hoffman TL, Doms RW. HIV-1 envelope determinants for cell tropism and chemokine receptor use. Molecular Membrane Biology. 16: 57-65. PMID 10332738  1
1999 Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW. Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages Proceedings of the National Academy of Sciences of the United States of America. 96: 5215-5220. PMID 10220446 DOI: 10.1073/pnas.96.9.5215  1
1999 Edinger AL, Blanpain C, Kunstman KJ, Wolinsky SM, Parmentier M, Doms RW. Functional dissection of CCR5 coreceptor function through the use of CD4-independent simian immunodeficiency virus strains. Journal of Virology. 73: 4062-73. PMID 10196302  1
1999 Martin V, Ronde P, Unett D, Wong A, Hoffman TL, Edinger AL, Doms RW, Funk CD. Leukotriene binding, signaling, and analysis of HIV coreceptor function in mouse and human leukotriene B4 receptor-transfected cells. The Journal of Biological Chemistry. 274: 8597-603. PMID 10085095 DOI: 10.1074/jbc.274.13.8597  1
1999 Doranz BJ, Orsini MJ, Turner JD, Hoffman TL, Berson JF, Hoxie JA, Peiper SC, Brass LF, Doms RW. Identification of CXCR4 domains that support coreceptor and chemokine receptor functions. Journal of Virology. 73: 2752-61. PMID 10074122  1
1999 Lee B, Ratajczak J, Doms RW, Gewirtz AM, Ratajczak MZ. Coreceptor/chemokine receptor expression on human hematopoietic cells: Biological implications for human immunodeficiency virus-type 1 infection Blood. 93: 1145-1156. PMID 9949156  1
1999 Albright AV, Shieh JT, Itoh T, Lee B, Pleasure D, O'Connor MJ, Doms RW, González-Scarano F. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates. Journal of Virology. 73: 205-13. PMID 9847323  1
1998 Hoxie JA, LaBranche CC, Endres MJ, Turner JD, Berson JF, Doms RW, Matthews TJ. CD4-independent utilization of the CXCR4 chemokine receptor by HIV-1 and HIV-2. Journal of Reproductive Immunology. 41: 197-211. PMID 10213311 DOI: 10.1016/S0165-0378(98)00059-X  1
1998 Rucker J, Doms RW. Chemokine receptors as HIV coreceptors: Implications and interactions Aids Research and Human Retroviruses. 14. PMID 9814950  1
1998 Edinger AL, Hoffman TL, Sharron M, Lee B, O'Dowd B, Doms RW. Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins. Virology. 249: 367-78. PMID 9791028 DOI: 10.1006/viro.1998.9306  1
1998 Hoffman TL, Stephens EB, Narayan O, Doms RW. HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors. Proceedings of the National Academy of Sciences of the United States of America. 95: 11360-5. PMID 9736741 DOI: 10.1073/pnas.95.19.11360  1
1998 Edinger AL, Hoffman TL, Sharron M, Lee B, Yi Y, Choe W, Kolson DL, Mitrovic B, Zhou Y, Faulds D, Collman RG, Hesselgesser J, Horuk R, Doms RW. An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus. Journal of Virology. 72: 7934-40. PMID 9733831  1
1998 Lee B, Doranz BJ, Rana S, Yi Y, Mellado M, Frade JMR, Martinez-A C, O'Brien SJ, Dean M, Collman RG, Doms RW. Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4 Journal of Virology. 72: 7450-7458. PMID 9696841  1
1998 Berson JF, Doms RW. Structure-function studies of the HIV-1 coreceptors. Seminars in Immunology. 10: 237-48. PMID 9653050 DOI: 10.1006/smim.1998.0130  1
1998 Hoffman TL, Doms RW. Chemokines and coreceptors in HIV/SIV-host interactions. Aids (London, England). 12: S17-26. PMID 9632980  1
1998 Skovronsky DM, Doms RW, Lee VM. Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture. The Journal of Cell Biology. 141: 1031-9. PMID 9585420 DOI: 10.1083/jcb.141.4.1031  1
1998 Shieh JT, Albright AV, Sharron M, Gartner S, Strizki J, Doms RW, González-Scarano F. Chemokine receptor utilization by human immunodeficiency virus type 1 isolates that replicate in microglia. Journal of Virology. 72: 4243-9. PMID 9557714  1
1998 Lee B, Doranz BJ, Ratajczak MZ, Doms RW. An intricate web: Chemokine receptors, HIV-1 and hematopoiesis Stem Cells. 16: 79-88. PMID 9554031  1
1998 Cho MW, Lee MK, Carney MC, Berson JF, Doms RW, Martin MA. Identification of determinants on a dualtropic human immunodeficiency virus type 1 envelope glycoprotein that confer usage of CXCR4. Journal of Virology. 72: 2509-15. PMID 9499115  1
1998 Berger EA, Doms RW, Fenyo EM, Korber BTM, Littman DR, Moore JP, Sattentau QJ, Schuitemaker H, Sodroski J, Weiss RA. A new classification for HIV-1 [6] Nature. 391: 240. PMID 9440686 DOI: 10.1038/34571  1
1998 Horuk R, Hesselgesser J, Zhou Y, Faulds D, Halks-Miller M, Harvey S, Taub D, Samson M, Parmentier M, Rucker J, Doranz BJ, Doms RW. The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains. The Journal of Biological Chemistry. 273: 386-91. PMID 9417093 DOI: 10.1074/jbc.273.1.386  1
1997 Edinger AL, Mankowski JL, Doranz BJ, Margulies BJ, Lee B, Rucker J, Sharron M, Hoffman TL, Berson JF, Zink MC, Hirsch VM, Clements JE, Doms RW. CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain. Proceedings of the National Academy of Sciences of the United States of America. 94: 14742-7. PMID 9405683 DOI: 10.1073/pnas.94.26.14742  1
1997 Forman MS, Cook DG, Leight S, Doms RW, Lee VM. Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells. The Journal of Biological Chemistry. 272: 32247-53. PMID 9405428 DOI: 10.1074/jbc.272.51.32247  1
1997 Rucker J, Doranz BJ, Edinger AL, Long D, Berson JF, Doms RW. Cell-cell fusion assay to study role of chemokine receptors in human immunodeficiency virus type 1 entry. Methods in Enzymology. 288: 118-33. PMID 9356991  1
1997 Doranz BJ, Grovit-Ferbas K, Sharron MP, Mao SH, Goetz MB, Daar ES, Doms RW, O'Brien WA. A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor Journal of Experimental Medicine. 186: 1395-1400. PMID 9334380 DOI: 10.1084/jem.186.8.1395  1
1997 Hoffman TL, MacGregor RR, Burger H, Mick R, Doms RW, Collman RG. CCR5 genotypes in sexually active couples discordant for human immunodeficiency virus type 1 infection status. The Journal of Infectious Diseases. 176: 1093-6. PMID 9333175  1
1997 Cook DG, Forman MS, Sung JC, Leight S, Kolson DL, Iwatsubo T, Lee VM, Doms RW. Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nature Medicine. 3: 1021-3. PMID 9288730 DOI: 10.1038/nm0997-1021  1
1997 Doms RW, Peiper SC. Unwelcomed guests with master keyes: How HIV uses chemokine receptors for cellular entry Virology. 235: 179-190. PMID 9281497 DOI: 10.1006/viro.1997.8703  1
1997 Chyung AS, Greenberg BD, Cook DG, Doms RW, Lee VM. Novel beta-secretase cleavage of beta-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells. The Journal of Cell Biology. 138: 671-80. PMID 9245794 DOI: 10.1083/jcb.138.3.671  1
1997 Earl PL, Broder CC, Doms RW, Moss B. Epitope map of human immunodeficiency virus type 1 gp41 derived from 47 monoclonal antibodies produced by immunization with oligomeric envelope protein Journal of Virology. 71: 2674-2684. PMID 9060620  1
1997 Doranz BJ, Berson JF, Rucker J, Doms RW. Chemokine receptors as fusion cofactors for human immunodeficiency virus type 1 (HIV-1). Immunologic Research. 16: 15-28. PMID 9048206 DOI: 10.1007/BF02786321  1
1996 Cook DG, Turner RS, Kolson DL, Lee VM, Doms RW. Vaccinia virus serves as an efficient vector for expressing heterologous proteins in human NTera 2 neurons. The Journal of Comparative Neurology. 374: 481-92. PMID 8910730 DOI: 10.1002/(SICI)1096-9861(19961028)374:4<481::AID-CNE1>3.0.CO;2-Y  1
1996 Rucker J, Samson M, Doranz BJ, Libert F, Berson JF, Yi Y, Smyth RJ, Collman RG, Broder CC, Vassart G, Doms RW, Parmentier M. Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity. Cell. 87: 437-46. PMID 8898197 DOI: 10.1016/S0092-8674(00)81364-1  1
1996 Cook DG, Sung JC, Golde TE, Felsenstein KM, Wojczyk BS, Tanzi RE, Trojanowski JQ, Lee VM, Doms RW. Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites. Proceedings of the National Academy of Sciences of the United States of America. 93: 9223-8. PMID 8799182 DOI: 10.1073/pnas.93.17.9223  1
1996 Berson JF, Long D, Doranz BJ, Rucker J, Jirik FR, Doms RW. A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. Journal of Virology. 70: 6288-95. PMID 8709256  1
1996 Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC, Parmentier M, Collman RG, Doms RW. A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell. 85: 1149-58. PMID 8674120 DOI: 10.1016/S0092-8674(00)81314-8  1
1996 Chunduru SK, Sutherland RM, Stewart GA, Doms RW, Paterson Y. Exploitation of the Vβ8.2 T cell receptor in protection against experimental autoimmune encephalomyelitis using a live vaccinia virus vector Journal of Immunology. 156: 4940-4945. PMID 8648145  1
1996 Richardson TM, Stryjewski BL, Broder CC, Hoxie JA, Mascola JR, Earl PL, Doms RW. Humoral response to oligomeric human immunodeficiency virus type 1 envelope protein Journal of Virology. 70: 753-762. PMID 8551612  1
1996 Berson JF, Doms RW, Long D. Interaction of human immunodeficiency virus type 1 envelope protein with liposomes containing galactosylceramide Perspectives in Drug Discovery and Design. 5: 169-180.  1
1995 Griffiths G, Doms RW, Mayhew T, Lucocq J. The bulk-flow hypothesis: not quite the end Trends in Cell Biology. 5: 9-13. DOI: 10.1016/S0962-8924(00)88926-6  1
1994 Sodeik B, Griffiths G, Ericsson M, Moss B, Doms RW. Assembly of vaccinia virus: Effects of rifampin on the intracellular distribution of viral protein p65 Journal of Virology. 68: 1103-1114. PMID 8289340  1
1994 Long D, Berson JF, Cook DG, Doms RW. Characterization of human immunodeficiency virus type 1 gp120 binding to liposomes containing galactosylceramide. Journal of Virology. 68: 5890-8. PMID 8057468  1
1994 Broder CC, Earl PL, Long D, Abedon ST, Moss B, Doms RW. Antigenic implications of human immunodeficiency virus type 1 envelope quaternary structure: Oligomer-specific and -sensitive monoclonal antibodies Proceedings of the National Academy of Sciences of the United States of America. 91: 11699-11703. PMID 7972127 DOI: 10.1073/pnas.91.24.11699  1
1994 Cook DG, Lee VM, Doms RW. Expression of foreign proteins in a human neuronal system Methods in Cell Biology. 43: 289-303. PMID 7823867  1
1994 Earl PL, Broder CC, Long D, Lee SA, Peterson J, Chakrabarti S, Doms RW, Moss B. Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities Journal of Virology. 68: 3015-3026. PMID 7512157  1
1993 Sodeik B, Doms RW, Ericsson M, Hiller G, Machamer CE, Van't Hof W, Van Meer G, Moss B, Griffiths G. Assembly of vaccinia virus: Role of the intermediate compartment between the endoplasmic reticulum and the Golgi stacks Journal of Cell Biology. 121: 521-542. PMID 8486734  1
1993 Doms RW, Lamb RA, Rose JK, Helenius A. Folding and assembly of viral membrane proteins. Virology. 193: 545-62. PMID 8460475 DOI: 10.1006/viro.1993.1164  1
1993 Doms RW. Protein conformational changes in virus-cell fusion Methods in Enzymology. 221: 61-72. PMID 8361386  1
1992 Earl PL, Doms RW, Moss B. Multimeric CD4 binding exhibited by human and simian immunodeficiency virus envelope protein dimers Journal of Virology. 66: 5610-5614. PMID 1501294  1
1991 Earl PL, Moss B, Doms RW. Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein Journal of Virology. 65: 2047-2055. PMID 1900540  1
1991 Doms RW, Earl PL, Moss B. The assembly of the HIV-1 env glycoprotein into dimers and tetramers Advances in Experimental Medicine and Biology. 300: 203-221. PMID 1781345  1
1990 Doms RW, Blumenthal R, Moss B. Fusion of intra- and extracellular forms of vaccinia virus with the cell membrane Journal of Virology. 64: 4884-4892. PMID 2398531  1
1990 Doms RW, Earl PL, Chakrabarti S, Moss B. Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus env proteins possess a functionally conserved assembly domain Journal of Virology. 64: 3537-3540. PMID 2352332  1
1990 Earl PL, Doms RW, Moss B. Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein Proceedings of the National Academy of Sciences of the United States of America. 87: 648-652. PMID 2300552  1
1990 Puri A, Booy FP, Doms RW, White JM, Blumenthal R. Conformational changes and fusion activity of influenza virus hemagglutinin of the H2 and H3 subtypes: Effects of acid pretreatment Journal of Virology. 64: 3824-3832. PMID 2196382  1
1990 Singh I, Doms RW, Wagner KR, Helenius A. Intracellular transport of soluble and membrane-bound glycoproteins: Folding, assembly and secretion of anchor-free influenza hemagglutinin Embo Journal. 9: 631-639. PMID 2178922  1
1990 Machamer CE, Doms RW, Bole DG, Helenius A, Rose JK. Heavy chain binding protein recognizes incompletely disulfide-bonded forms of vesicular stomatitis virus G protein. The Journal of Biological Chemistry. 265: 6879-83. PMID 2157712  1
1990 Doms RW. Oligomerization and protein transport Methods in Enzymology. 191: 841-854. PMID 2127449  1
1989 Doms RW, Russ G, Yewdell JW. Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum Journal of Cell Biology. 109: 61-72. PMID 2745557  1
1989 Stegmann T, Doms RW, Helenius A. Protein-mediated membrane fusion Annual Review of Biophysics and Biophysical Chemistry. 18: 187-211. PMID 2660823  1
1988 Boulay F, Doms RW, Webster RG, Helenius A. Posttranslational oligomerization and cooperative acid activation of mixed influenza hemagglutinin trimers Journal of Cell Biology. 106: 629-639. PMID 3279048  1
1988 Rose JK, Doms RW. Regulation of protein export from the endoplasmic reticulum. Annual Review of Cell Biology. 4: 257-88. PMID 3058161 DOI: 10.1146/annurev.cb.04.110188.001353  1
1988 Doms RW, Ruusala A, Machamer C, Helenius J, Helenius A, Rose JK. Differential effects of mutations in three domains on folding, quaternary structure, and intracellular transport of vesicular stomatitis virus G protein. The Journal of Cell Biology. 107: 89-99. PMID 2839523  1
1988 Whitt MA, Doms RW, Ruusala A, Helenius J, Helenius A, Rose JK. Dual roles for the cytoplasmic domain of the VSV G protein: Protein transport and virus assembly Virus Research. 11: 6.  1
1987 Boulay F, Doms RW, Wilson I, Helenius A. The influenza hemagglutinin precursor as an acid-sensitive probe of the biosynthetic pathway Embo Journal. 6: 2643-2650. PMID 3315651  1
1987 Doms RW, Keller DS, Helenius A, Balch WE. Role for adenosine triphosphate in regulating the assembly and transport of vesicular stomatitis virus G protein trimers Journal of Cell Biology. 105: 1957-1969. PMID 2824524  1
1986 Doms RW, Helenius A. Quaternary structure of influenza virus hemagglutinin after acid treatment Journal of Virology. 60: 833-839. PMID 3783818  1
1986 Gething MJ, Doms RW, York D, White J. Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virus. The Journal of Cell Biology. 102: 11-23. PMID 3753607  1
1986 Doms RW, Gething MJ, Henneberry J, White J, Helenius A. Variant influenza virus hemagglutinin that induces fusion at elevated pH. Journal of Virology. 57: 603-13. PMID 3003392  1
1986 Copeland CS, Doms RW, Bolzau EM, Webster RG, Helenius A. Assembly of influenza hemagglutinin trimers and its role in intracellular transport. The Journal of Cell Biology. 103: 1179-91. PMID 2429970 DOI: 10.1083/jcb.103.4.1179  1
1985 Doms RW, Helenius A, White J. Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change Journal of Biological Chemistry. 260: 2973-2981. PMID 3972812  1
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