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Una O'Doherty - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Virology Biology, Microbiology Biology, Molecular Biology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lee SA, Bacchetti P, Chomont N, Fromentin R, Lewin SR, O'Doherty U, Palmer S, Richman DD, Siliciano JD, Yukl SA, Deeks SG, Burbelo PD. Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy. Plos One. 11: e0160192. PMID 27483366 DOI: 10.1371/journal.pone.0160192  0.68
2016 Imamichi H, Dewar RL, Adelsberger JW, Rehm CA, O'Doherty U, Paxinos EE, Fauci AS, Lane HC. Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27432972 DOI: 10.1073/pnas.1609057113  0.68
2015 Pasternak AO, DeMaster LK, Kootstra NA, Reiss P, O'Doherty U, Berkhout B. Minor Contribution of Chimeric Host-HIV Readthrough Transcripts to the Level of HIV Cell-Associated gag RNA. Journal of Virology. 90: 1148-51. PMID 26559833 DOI: 10.1128/JVI.02597-15  0.68
2015 DeMaster LK, Liu X, VanBelzen DJ, Trinité B, Zheng L, Agosto LM, Migueles SA, Connors M, Sambucetti L, Levy DN, Pasternak AO, O'Doherty U. A subset of CD4/CD8 double negative T cells expresses HIV proteins in patients on ART. Journal of Virology. PMID 26537682 DOI: 10.1128/JVI.01913-15  0.68
2015 Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJO, Miller MD, Hazuda DJ, Deeks SG, et al. A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals Ebiomedicine. DOI: 10.1016/j.ebiom.2015.06.019  0.68
2014 Aqui N, O'Doherty U. Leukocytapheresis for the treatment of hyperleukocytosis secondary to acute leukemia. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2014: 457-60. PMID 25696894 DOI: 10.1182/asheducation-2014.1.457  0.68
2014 Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. Plos One. 9: e110731. PMID 25340755 DOI: 10.1371/journal.pone.0110731  0.68
2014 Garfall AL, Dougherty AL, Vogl DT, Weiss BM, Cohen AD, Mick R, O'Doherty U, Stadtmauer EA. Association between mobilization regimen and PFS after auto-SCT for multiple myeloma. Bone Marrow Transplantation. 49: 1439-41. PMID 25046220 DOI: 10.1038/bmt.2014.153  0.68
2014 De Spiegelaere W, Malatinkova E, Lynch L, Van Nieuwerburgh F, Messiaen P, O'Doherty U, Vandekerckhove L. Quantification of integrated HIV DNA by repetitive-sampling Alu-HIV PCR on the basis of poisson statistics. Clinical Chemistry. 60: 886-95. PMID 24664400 DOI: 10.1373/clinchem.2013.219378  0.68
2013 Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, et al. Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. Plos Pathogens. 9: e1003691. PMID 24130489 DOI: 10.1371/journal.ppat.1003691  0.68
2013 Sherrill-Mix S, Lewinski MK, Famiglietti M, Bosque A, Malani N, Ocwieja KE, Berry CC, Looney D, Shan L, Agosto LM, Pace MJ, Siliciano RF, O'Doherty U, Guatelli J, Planelles V, et al. HIV latency and integration site placement in five cell-based models. Retrovirology. 10: 90. PMID 23953889 DOI: 10.1186/1742-4690-10-90  0.68
2013 Graf EH, Pace MJ, Peterson BA, Lynch LJ, Chukwulebe SB, Mexas AM, Shaheen F, Martin JN, Deeks SG, Connors M, Migueles SA, O'Doherty U. Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected]. Plos One. 8: e71879. PMID 23951263 DOI: 10.1371/journal.pone.0071879  0.68
2013 Azzoni L, Foulkes AS, Papasavvas E, Mexas AM, Lynn KM, Mounzer K, Tebas P, Jacobson JM, Frank I, O'Doherty U, Kostman J, Montaner LJ. Improved treatment for primary HIV infection by interferon-alfa therapy? Does HCV treatment in HIV/HCV coinfected patients help us to test this hypothesis? Reply to zur Wiesch and van Lunzen. The Journal of Infectious Diseases. 208: 363. PMID 23570845 DOI: 10.1093/infdis/jit160  0.68
2013 Pace M, O'Doherty U. Hematopoietic stem cells and HIV infection. The Journal of Infectious Diseases. 207: 1790-2. PMID 23554379 DOI: 10.1093/infdis/jit120  0.68
2013 Pace MJ, Graf EH, O'Doherty U. HIV 2-long terminal repeat circular DNA is stable in primary CD4+T Cells. Virology. 441: 18-21. PMID 23537959 DOI: 10.1016/j.virol.2013.02.028  0.68
2013 Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, et al. Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. Plos Pathogens. 9: e1003174. PMID 23459007 DOI: 10.1371/journal.ppat.1003174  0.68
2013 Tanhehco YC, Vogl DT, Stadtmauer EA, O'Doherty U. The evolving role of plerixafor in hematopoietic progenitor cell mobilization. Transfusion. 53: 2314-26. PMID 23362980 DOI: 10.1111/trf.12102  0.68
2013 Brady T, Kelly BJ, Male F, Roth S, Bailey A, Malani N, Gijsbers R, O'Doherty U, Bushman FD. Quantitation of HIV DNA integration: effects of differential integration site distributions on Alu-PCR assays. Journal of Virological Methods. 189: 53-7. PMID 23348058 DOI: 10.1016/j.jviromet.2013.01.004  0.68
2013 Graf EH, O'Doherty U. Quantitation of integrated proviral DNA in viral reservoirs. Current Opinion in Hiv and Aids. 8: 100-5. PMID 23340051 DOI: 10.1097/COH.0b013e32835d8132  0.68
2013 Azzoni L, Foulkes AS, Papasavvas E, Mexas AM, Lynn KM, Mounzer K, Tebas P, Jacobson JM, Frank I, Busch MP, Deeks SG, Carrington M, O'Doherty U, Kostman J, Montaner LJ. Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration. The Journal of Infectious Diseases. 207: 213-22. PMID 23105144 DOI: 10.1093/infdis/jis663  0.68
2012 Andrzejewski C, Linz W, Hofmann J, O'Doherty U, Robinson RS, Arepally GM, Golden P. American Society for Apheresis white paper: considerations for medical staff apheresis medicine physician credentialing and privileging. Journal of Clinical Apheresis. 27: 330-5. PMID 23124963 DOI: 10.1002/jca.21250  0.68
2012 Mexas AM, Graf EH, Pace MJ, Yu JJ, Papasavvas E, Azzoni L, Busch MP, Di Mascio M, Foulkes AS, Migueles SA, Montaner LJ, O'Doherty U. Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials. Aids (London, England). 26: 2295-306. PMID 23014521 DOI: 10.1097/QAD.0b013e32835a5c2f  0.68
2012 Pace MJ, Graf EH, Agosto LM, Mexas AM, Male F, Brady T, Bushman FD, O'Doherty U. Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency. Plos Pathogens. 8: e1002818. PMID 22911005 DOI: 10.1371/journal.ppat.1002818  0.68
2012 Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A, Lederman M, Lewin SR, et al. Towards an HIV cure: a global scientific strategy. Nature Reviews. Immunology. 12: 607-14. PMID 22814509 DOI: 10.1038/nri3262  0.68
2012 Mendoza D, Johnson SA, Peterson BA, Natarajan V, Salgado M, Dewar RL, Burbelo PD, Doria-Rose NA, Graf EH, Greenwald JH, Hodge JN, Thompson WL, Cogliano NA, Chairez CL, Rehm CA, et al. Comprehensive analysis of unique cases with extraordinary control over HIV replication. Blood. 119: 4645-55. PMID 22490332 DOI: 10.1182/blood-2011-10-381996  0.68
2011 Graf EH, Mexas AM, Yu JJ, Shaheen F, Liszewski MK, Di Mascio M, Migueles SA, Connors M, O'Doherty U. Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART. Plos Pathogens. 7: e1001300. PMID 21383972 DOI: 10.1371/journal.ppat.1001300  0.68
2011 Pace MJ, Agosto L, Graf EH, O'Doherty U. HIV reservoirs and latency models. Virology. 411: 344-54. PMID 21284992 DOI: 10.1016/j.virol.2010.12.041  0.68
2011 Pace MJ, Agosto L, O'Doherty U. R5 HIV env and vesicular stomatitis virus G protein cooperate to mediate fusion to naive CD4+ T Cells. Journal of Virology. 85: 644-8. PMID 20980513 DOI: 10.1128/JVI.01851-10  0.68
2011 Agosto LM, Liszewski MK, Mexas A, Graf E, Pace M, Yu JJ, Bhandoola A, O'Doherty U. Patients on HAART often have an excess of unintegrated HIV DNA: implications for monitoring reservoirs. Virology. 409: 46-53. PMID 20970154 DOI: 10.1016/j.virol.2010.08.024  0.68
2011 Nazha A, Cook R, Vogl DT, Mangan PA, Gardler M, Hummel K, Cunningham K, Luger SM, Porter DL, Schuster S, O'Doherty U, Siegel D, Stadtmauer EA. Stem cell collection in patients with multiple myeloma: impact of induction therapy and mobilization regimen. Bone Marrow Transplantation. 46: 59-63. PMID 20421869 DOI: 10.1038/bmt.2010.63  0.68
2010 Tanhehco YC, Adamski J, Sell M, Cunningham K, Eisenmann C, Magee D, Stadtmauer EA, O'Doherty U. Plerixafor mobilization leads to a lower ratio of CD34+ cells to total nucleated cells which results in greater storage costs. Journal of Clinical Apheresis. 25: 202-8. PMID 20818715 DOI: 10.1002/jca.20239  0.68
2009 Brady T, Agosto LM, Malani N, Berry CC, O'Doherty U, Bushman F. HIV integration site distributions in resting and activated CD4+ T cells infected in culture. Aids (London, England). 23: 1461-71. PMID 19550285 DOI: 10.1097/QAD.0b013e32832caf28  0.68
2009 Agosto LM, Yu JJ, Liszewski MK, Baytop C, Korokhov N, Humeau LM, O'Doherty U. The CXCR4-tropic human immunodeficiency virus envelope promotes more-efficient gene delivery to resting CD4+ T cells than the vesicular stomatitis virus glycoprotein G envelope. Journal of Virology. 83: 8153-62. PMID 19493998 DOI: 10.1128/JVI.00220-09  0.68
2009 Dai J, Agosto LM, Baytop C, Yu JJ, Pace MJ, Liszewski MK, O'Doherty U. Human immunodeficiency virus integrates directly into naive resting CD4+ T cells but enters naive cells less efficiently than memory cells. Journal of Virology. 83: 4528-37. PMID 19211752 DOI: 10.1128/JVI.01910-08  0.68
2009 Liszewski MK, Yu JJ, O'Doherty U. Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR. Methods (San Diego, Calif.). 47: 254-60. PMID 19195495 DOI: 10.1016/j.ymeth.2009.01.002  0.68
2008 Yu JJ, Wu TL, Liszewski MK, Dai J, Swiggard WJ, Baytop C, Frank I, Levine BL, Yang W, Theodosopoulos T, O'Doherty U. A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients. Virology. 379: 78-86. PMID 18649912 DOI: 10.1016/j.virol.2008.05.030  0.68
2007 Plesa G, Dai J, Baytop C, Riley JL, June CH, O'Doherty U. Addition of deoxynucleosides enhances human immunodeficiency virus type 1 integration and 2LTR formation in resting CD4+ T cells. Journal of Virology. 81: 13938-42. PMID 17928354 DOI: 10.1128/JVI.01745-07  0.68
2007 Nelson PT, De Planell-Saguer M, Lamprinaki S, Kiriakidou M, Zhang P, O'Doherty U, Mourelatos Z. A novel monoclonal antibody against human Argonaute proteins reveals unexpected characteristics of miRNAs in human blood cells. Rna (New York, N.Y.). 13: 1787-92. PMID 17720879 DOI: 10.1261/rna.646007  0.68
2007 Agosto LM, Yu JJ, Dai J, Kaletsky R, Monie D, O'Doherty U. HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration. Virology. 368: 60-72. PMID 17631931 DOI: 10.1016/j.virol.2007.06.001  0.68
2005 Swiggard WJ, Baytop C, Yu JJ, Dai J, Li C, Schretzenmair R, Theodosopoulos T, O'Doherty U. Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli. Journal of Virology. 79: 14179-88. PMID 16254353 DOI: 10.1128/JVI.79.22.14179-14188.2005  0.68
2005 O'Doherty U. Mechanisms of human immunodeficiency virus-1 latency. Transfusion. 45: 88S-91S. PMID 16086794 DOI: 10.1111/j.1537-2995.2005.00538.x  0.68
2004 Swiggard WJ, O'Doherty U, McGain D, Jeyakumar D, Malim MH. Long HIV type 1 reverse transcripts can accumulate stably within resting CD4+ T cells while short ones are degraded. Aids Research and Human Retroviruses. 20: 285-95. PMID 15117452 DOI: 10.1089/088922204322996527  0.68
2002 O'Doherty U, Swiggard WJ, Jeyakumar D, McGain D, Malim MH. A sensitive, quantitative assay for human immunodeficiency virus type 1 integration. Journal of Virology. 76: 10942-50. PMID 12368337 DOI: 10.1128/JVI.76.21.10942-10950.2002  0.68
2001 Lee B, Leslie G, Soilleux E, O'Doherty U, Baik S, Levroney E, Flummerfelt K, Swiggard W, Coleman N, Malim M, Doms RW. cis expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor Journal of Virology. 75: 12028-12038. PMID 11711593 DOI: 10.1128/JVI.75.24.12028-12038.2001  0.68
2000 O'Doherty U, Swiggard WJ, Malim MH. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding Journal of Virology. 74: 10074-10080. PMID 11024136 DOI: 10.1128/JVI.74.21.10074-10080.2000  0.68
1999 Hu J, Miller CJ, O'Doherty U, Marx PA, Pope M. The dendritic cell-T cell milieu of the lymphoid tissue of the tonsil provides a locale in which SIV can reside and propagate at chronic stages of infection. Aids Research and Human Retroviruses. 15: 1305-14. PMID 10505679 DOI: 10.1089/088922299310205  0.68
1998 Ignatius R, Isdell F, O'Doherty U, Pope M. Dendritic cells from skin and blood of macaques both promote SIV replication with T cells from different anatomical sites Journal of Medical Primatology. 27: 121-128. PMID 9747953  0.68
1998 Hu J, Pope M, Brown C, O'Doherty U, Miller CJ. Immunophenotypic characterization of simian immunodeficiency virus-infected dendritic cells in cervix, vagina, and draining lymph nodes of rhesus monkeys. Laboratory Investigation; a Journal of Technical Methods and Pathology. 78: 435-51. PMID 9564888  0.68
1997 O'Doherty U, Ignatius R, Bhardwaj N, Pope M. Generation of monocyte-derived dendritic cells from precursors in rhesus macaque blood Journal of Immunological Methods. 207: 185-194. PMID 9368645 DOI: 10.1016/S0022-1759(97)00119-1  0.68
1996 Granelli-Piperno A, Moser B, Pope M, Chen D, Wei Y, Isdell F, O'Doherty U, Paxton W, Koup R, Mojsov S, Bhardwaj N, Clark-Lewis I, Baggiolini M, Steinman RM. Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors. The Journal of Experimental Medicine. 184: 2433-8. PMID 8976200 DOI: 10.1084/jem.184.6.2433  0.68
1995 Yamaguchi Y, O'Doherty U, Peng M, Steinman RM. Difficulties in obtaining monoclonal antibodies to subsets of human leukocytes, using neonatal tolerance induction in mice. Journal of Immunological Methods. 181: 115-24. PMID 7730660  0.68
1994 Cameron PU, Lowe MG, Crowe SM, O'Doherty U, Pope M, Gezelter S, Steinman RM. Susceptibility of dendritic cells to HIV-1 infection in vitro. Journal of Leukocyte Biology. 56: 257-65. PMID 8083598  0.68
1994 O'Doherty U, Peng M, Gezelter S, Swiggard WJ, Betjes M, Bhardwaj N, Steinman RM. Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature. Immunology. 82: 487-93. PMID 7525461  0.68
1993 O'Doherty U, Swiggard WJ, Inaba K, Yamaguchi Y, Kopeloff I, Bhardwaj N, Steinman RM. Tolerizing mice to human leukocytes: a step toward the production of monoclonal antibodies specific for human dendritic cells. Advances in Experimental Medicine and Biology. 329: 165-72. PMID 8379367  0.68
1993 O'Doherty U, Steinman RM, Peng M, Cameron PU, Gezelter S, Kopeloff I, Swiggard WJ, Pope M, Bhardwaj N. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. The Journal of Experimental Medicine. 178: 1067-76. PMID 8102389  0.68
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