Daniel J. Rader - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology

239 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Quach D, Vitali C, La FM, Xiao AX, Millar JS, Tang C, Rader DJ, Phillips MC, Lyssenko NN. Cell lipid metabolism modulators 2-bromopalmitate, D609, monensin, U18666A and probucol shift discoidal HDL formation to the smaller-sized particles: implications for the mechanism of HDL assembly. Biochimica Et Biophysica Acta. PMID 27671775 DOI: 10.1016/j.bbalip.2016.09.017  0.76
2016 Joshi AA, Lerman JB, Aberra TM, Afshar M, Teague HL, Rodante JA, Krishnamoorthy P, Ng Q, Aridi TZ, Salahuddin T, Natarajan B, Lockshin BN, Ahlman MA, Chen MY, Rader DJ, et al. GlycA Is a Novel Biomarker of Inflammation and Subclinical Cardiovascular Disease in Psoriasis. Circulation Research. PMID 27654120 DOI: 10.1161/CIRCRESAHA.116.309637  0.76
2016 Khetarpal SA, Schjoldager KT, Christoffersen C, Raghavan A, Edmondson AC, Reutter HM, Ahmed B, Ouazzani R, Peloso GM, Vitali C, Zhao W, Somasundara AV, Millar JS, Park Y, Fernando G, ... ... Rader DJ, et al. Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents. Cell Metabolism. 24: 234-245. PMID 27508872 DOI: 10.1016/j.cmet.2016.07.012  0.76
2016 Hsieh J, Koseki M, Molusky MM, Yakushiji E, Ichi I, Westerterp M, Iqbal J, Chan RB, Abramowicz S, Tascau L, Takiguchi S, Yamashita S, Welch CL, Di Paolo G, Hussain MM, ... ... Rader DJ, et al. TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis. Nature. PMID 27383786 DOI: 10.1038/nature18628  0.76
2016 Daugherty A, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C. Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 1303-4. PMID 27335467 DOI: 10.1161/ATVBAHA.116.307906  0.76
2016 Lin J, Hu Y, Nunez S, Foulkes AS, Cieply B, Xue C, Gerelus M, Li W, Zhang H, Rader DJ, Musunuru K, Li M, Reilly MP. Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27230130 DOI: 10.1161/ATVBAHA.116.307573  0.76
2016 Patel AP, Peloso GM, Pirruccello JP, Johansen CT, Dubé JB, Larach DB, Ban MR, Dallinge-Thie GM, Gupta N, Boehnke M, Abecasis GR, Kastelein JJ, Hovingh GK, Hegele RA, Rader DJ, et al. Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution. Atherosclerosis. 250: 63-68. PMID 27182959 DOI: 10.1016/j.atherosclerosis.2016.04.011  0.76
2016 Khera AV, Won HH, Peloso GM, Lawson KS, Bartz TM, Deng X, van Leeuwen EM, Natarajan P, Emdin CA, Bick AG, Morrison AC, Brody JA, Gupta N, Nomura A, Kessler T, ... ... Rader DJ, et al. Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia. Journal of the American College of Cardiology. PMID 27050191 DOI: 10.1016/j.jacc.2016.03.520  0.76
2016 deGoma EM, Ahmad ZS, O'Brien EC, Kindt I, Shrader P, Newman CB, Pokharel Y, Baum SJ, Hemphill LC, Hudgins LC, Ahmed CD, Gidding SS, Duffy D, Neal W, Wilemon K, ... ... Rader DJ, et al. Treatment Gaps in Adults with Heterozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE-FH Registry. Circulation. Cardiovascular Genetics. PMID 27013694 DOI: 10.1161/CIRCGENETICS.116.001381  0.76
2016 Bauer RC, Khetarpal SA, Hand NJ, Rader DJ. Therapeutic Targets of Triglyceride Metabolism as Informed by Human Genetics. Trends in Molecular Medicine. PMID 26988439 DOI: 10.1016/j.molmed.2016.02.005  0.76
2016 Reyes-Soffer G, Millar JS, Ngai C, Jumes P, Coromilas E, Asztalos B, Johnson-Levonas AO, Wagner JA, Donovan DS, Karmally W, Ramakrishnan R, Holleran S, Thomas T, Dunbar RL, deGoma EM, ... ... Rader DJ, et al. Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Increases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26966279 DOI: 10.1161/ATVBAHA.115.306680  0.76
2016 Zanoni P, Khetarpal SA, Larach DB, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A, Surendran P, Saleheen D, Trompet S, Jukema JW, De Craen A, Deloukas P, Sattar N, ... ... Rader DJ, et al. Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science (New York, N.Y.). 351: 1166-71. PMID 26965621 DOI: 10.1126/science.aad3517  0.76
2016 Goettsch C, Hutcheson JD, Aikawa M, Iwata H, Pham T, Nykjaer A, Kjolby M, Rogers M, Michel T, Shibasaki M, Hagita S, Kramann R, Rader DJ, Libby P, Singh SA, et al. Sortilin mediates vascular calcification via its recruitment into extracellular vesicles. The Journal of Clinical Investigation. PMID 26950419 DOI: 10.1172/JCI80851  0.76
2016 Clapham KR, Chu AY, Wessel J, Natarajan P, Flannick J, Rivas MA, Sartori S, Mehran R, Baber U, Fuster V, Scott RA, Rader DJ, Boehnke M, McCarthy MI, Altshuler DM, et al. A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans. Bmc Endocrine Disorders. 16: 7. PMID 26822414 DOI: 10.1186/s12902-016-0088-8  0.76
2016 Keenan T, Zhao W, Rasheed A, Ho WK, Malik R, Felix JF, Young R, Shah N, Samuel M, Sheikh N, Mucksavage ML, Shah O, Li J, Morley M, Laser A, ... ... Rader DJ, et al. Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study. Journal of the American College of Cardiology. 67: 407-16. PMID 26821629 DOI: 10.1016/j.jacc.2015.10.086  0.76
2016 Ibrahim S, Somanathan S, Billheimer J, Wilson JM, Rader DJ. Stable Liver-specific Expression of Human IDOL in Humanized Mice Raises Plasma Cholesterol. Cardiovascular Research. PMID 26786161 DOI: 10.1093/cvr/cvw010  0.76
2016 Kastelein JJ, Nissen SE, Rader DJ, Hovingh GK, Wang MD, Shen T, Krueger KA. Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study. European Heart Journal. PMID 26757788 DOI: 10.1093/eurheartj/ehv707  0.76
2015 Voight BF, Rader DJ. Human genetics shines a light on ischaemic stroke. The Lancet. Neurology. PMID 26708677 DOI: 10.1016/S1474-4422(15)00400-7  0.76
2015 Herzog E, Pragst I, Waelchli M, Gille A, Schenk S, Mueller-Cohrs J, Diditchenko S, Zanoni P, Cuchel M, Seubert A, Rader DJ, Wright SD. Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component. Journal of Applied Toxicology : Jat. PMID 26651060 DOI: 10.1002/jat.3264  0.76
2015 Nicholls SJ, Ruotolo G, Brewer HB, Kane JP, Wang MD, Krueger KA, Adelman SJ, Nissen SE, Rader DJ. Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib. Journal of the American College of Cardiology. 66: 2201-10. PMID 26564598 DOI: 10.1016/j.jacc.2015.09.013  0.76
2015 Bauer RC, Yenilmez BO, Rader DJ. Tribbles-1: a novel regulator of hepatic lipid metabolism in humans. Biochemical Society Transactions. 43: 1079-84. PMID 26517927 DOI: 10.1042/BST20150101  0.76
2015 Natarajan P, Kohli P, Baber U, Nguyen KD, Sartori S, Reilly DF, Mehran R, Muntendam P, Fuster V, Rader DJ, Kathiresan S. Association of APOC3 Loss-of-Function Mutations With Plasma Lipids and Subclinical Atherosclerosis: The Multi-Ethnic BioImage Study. Journal of the American College of Cardiology. 66: 2053-5. PMID 26516010 DOI: 10.1016/j.jacc.2015.08.866  0.76
2015 Hegele RA, Gidding SS, Ginsberg HN, McPherson R, Raal FJ, Rader DJ, Robinson JG, Welty FK. Nonstatin Low-Density Lipoprotein-Lowering Therapy and Cardiovascular Risk Reduction-Statement From ATVB Council. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2269-80. PMID 26376908 DOI: 10.1161/ATVBAHA.115.306442  0.76
2015 Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, et al. Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. The Journal of Clinical Investigation. PMID 26368306 DOI: 10.1172/JCI79048  0.76
2015 Rader DJ. Lysosomal Acid Lipase Deficiency--A New Therapy for a Genetic Lipid Disease. The New England Journal of Medicine. 373: 1071-3. PMID 26352819 DOI: 10.1056/NEJMe1509055  0.76
2015 Peloso GM, Rader DJ, Gabriel S, Kathiresan S, Daly MJ, Neale BM. Phenotypic extremes in rare variant study designs. European Journal of Human Genetics : Ejhg. PMID 26350511 DOI: 10.1038/ejhg.2015.197  0.76
2015 Iqbal J, Walsh MT, Hammad SM, Cuchel M, Tarugi P, Hegele RA, Davidson NO, Rader DJ, Klein RL, Hussain MM. Microsomal triglyceride transfer protein transfers and determines plasma concentrations of ceramide and sphingomyelin, but not glycosylceramide. The Journal of Biological Chemistry. PMID 26350457 DOI: 10.1074/jbc.M115.659110  0.76
2015 Bauer RC, Sasaki M, Cohen DM, Cui J, Smith MA, Yenilmez BO, Steger DJ, Rader DJ. Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα. The Journal of Clinical Investigation. PMID 26348894 DOI: 10.1172/JCI77095  0.76
2015 Asch DA, Rader DJ, Merchant RM. Mining the social mediome. Trends in Molecular Medicine. 21: 528-9. PMID 26341614 DOI: 10.1016/j.molmed.2015.06.004  0.76
2015 Yang W, Liu Y, Slovik KJ, Wu JC, Duncan SA, Rader DJ, Morrisey EE. Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells. Plos One. 10: e0134995. PMID 26281015 DOI: 10.1371/journal.pone.0134995  0.76
2015 Hovingh GK, Kastelein JJ, van Deventer SJ, Round P, Ford J, Saleheen D, Rader DJ, Brewer HB, Barter PJ. Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial. Lancet (London, England). 386: 452-60. PMID 26047975 DOI: 10.1016/S0140-6736(15)60158-1  0.76
2015 Millar JS, Reyes-Soffer G, Jumes P, Dunbar RL, deGoma EM, Baer AL, Karmally W, Donovan DS, Rafeek H, Pollan L, Tohyama J, Johnson-Levonas AO, Wagner JA, Holleran S, Obunike J, ... ... Rader DJ, et al. Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects. The Journal of Clinical Investigation. 125: 2510-22. PMID 25961461 DOI: 10.1172/JCI80025  0.76
2015 Zhang H, Xue C, Shah R, Bermingham K, Hinkle CC, Li W, Rodrigues A, Tabita-Martinez J, Millar JS, Cuchel M, Pashos EE, Liu Y, Yan R, Yang W, Gosai SJ, ... ... Rader DJ, et al. Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease. Circulation Research. 117: 17-28. PMID 25904599 DOI: 10.1161/CIRCRESAHA.117.305860  0.76
2015 Agarwala AP, Rodrigues A, Risman M, McCoy M, Trindade K, Qu L, Cuchel M, Billheimer J, Rader DJ. High-Density Lipoprotein (HDL) Phospholipid Content and Cholesterol Efflux Capacity Are Reduced in Patients With Very High HDL Cholesterol and Coronary Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1515-9. PMID 25838421 DOI: 10.1161/ATVBAHA.115.305504  0.76
2015 Rader DJ. Human genetics of atherothrombotic disease and its risk factors. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 741-7. PMID 25810293 DOI: 10.1161/ATVBAHA.115.305492  0.76
2015 Shah R, Matthews GJ, Shah RY, McLaughlin C, Chen J, Wolman M, Master SR, Chai B, Xie D, Rader DJ, Raj DS, Mehta NN, Budoff M, Fischer MJ, Go AS, et al. Serum Fractalkine (CX3CL1) and Cardiovascular Outcomes and Diabetes: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 25795074 DOI: 10.1053/j.ajkd.2015.01.021  0.76
2015 Bauer RC, Tohyama J, Cui J, Cheng L, Yang J, Zhang X, Ou K, Paschos GK, Zheng XL, Parmacek MS, Rader DJ, Reilly MP. Knockout of Adamts7, a novel coronary artery disease locus in humans, reduces atherosclerosis in mice. Circulation. 131: 1202-13. PMID 25712206 DOI: 10.1161/CIRCULATIONAHA.114.012669  0.76
2015 deGoma EM, Salavati A, Shinohara RT, Saboury B, Pollan L, Schoen M, Torigian DA, Mohler ER, Dunbar RL, Litt HI, Woo J, Rader DJ, Alavi A, Mehta NN. A pilot trial to examine the effect of high-dose niacin on arterial wall inflammation using fluorodeoxyglucose positron emission tomography. Academic Radiology. 22: 600-9. PMID 25708866 DOI: 10.1016/j.acra.2014.12.015  0.76
2015 Luthi AJ, Lyssenko NN, Quach D, McMahon KM, Millar JS, Vickers KC, Rader DJ, Phillips MC, Mirkin CA, Thaxton CS. Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein. Journal of Lipid Research. 56: 972-85. PMID 25652088 DOI: 10.1194/jlr.M054635  0.76
2015 Thormaehlen AS, Schuberth C, Won HH, Blattmann P, Joggerst-Thomalla B, Theiss S, Asselta R, Duga S, Merlini PA, Ardissino D, Lander ES, Gabriel S, Rader DJ, Peloso GM, Pepperkok R, et al. Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction. Plos Genetics. 11: e1004855. PMID 25647241 DOI: 10.1371/journal.pgen.1004855  0.76
2015 Stitziel NO, Peloso GM, Abifadel M, Cefalu AB, Fouchier S, Motazacker MM, Tada H, Larach DB, Awan Z, Haller JF, Pullinger CR, Varret M, Rabès JP, Noto D, Tarugi P, ... ... Rader DJ, et al. Exome sequencing in suspected monogenic dyslipidemias. Circulation. Cardiovascular Genetics. 8: 343-50. PMID 25632026 DOI: 10.1161/CIRCGENETICS.114.000776  0.76
2015 Patel KM, Strong A, Tohyama J, Jin X, Morales CR, Billheimer J, Millar J, Kruth H, Rader DJ. Macrophage sortilin promotes LDL uptake, foam cell formation, and atherosclerosis. Circulation Research. 116: 789-96. PMID 25593281 DOI: 10.1161/CIRCRESAHA.116.305811  0.76
2015 Khetarpal SA, Rader DJ. Triglyceride-rich lipoproteins and coronary artery disease risk: new insights from human genetics. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: e3-9. PMID 25573854 DOI: 10.1161/ATVBAHA.114.305172  0.76
2015 Daugherty A, Tabas I, Rader DJ. Accelerating the pace of atherosclerosis research. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 11-2. PMID 25520521 DOI: 10.1161/ATVBAHA.114.304833  0.76
2015 Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL, ... ... Rader DJ, et al. Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature. 518: 102-6. PMID 25487149 DOI: 10.1038/nature13917  0.76
2015 Khera AV, Qamar A, Reilly MP, Dunbar RL, Rader DJ. Effects of niacin, statin, and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 levels in patients with dyslipidemia. The American Journal of Cardiology. 115: 178-82. PMID 25432415 DOI: 10.1016/j.amjcard.2014.10.018  0.76
2015 Rader DJ, Khetarpal SA. Lipoprotein physiology Dyslipidemias: Pathophysiology, Evaluation and Management. 1-12. DOI: 10.1007/978-1-60761-424-1_1  0.76
2014 Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, König I, ... ... Rader DJ, et al. Inactivating mutations in NPC1L1 and protection from coronary heart disease. The New England Journal of Medicine. 371: 2072-82. PMID 25390462 DOI: 10.1056/NEJMoa1405386  0.76
2014 Tuteja S, Rader DJ. Dyslipidaemia: cardiovascular prevention--end of the road for niacin? Nature Reviews. Endocrinology. 10: 646-7. PMID 25178730 DOI: 10.1038/nrendo.2014.159  0.76
2014 Yang P, Belikova NA, Billheimer J, Rader DJ, Hill JS, Subbaiah PV. Inhibition of endothelial lipase activity by sphingomyelin in the lipoproteins. Lipids. 49: 987-96. PMID 25167836 DOI: 10.1007/s11745-014-3944-1  0.76
2014 Rader DJ, Hovingh GK. HDL and cardiovascular disease. Lancet (London, England). 384: 618-25. PMID 25131981 DOI: 10.1016/S0140-6736(14)61217-4  0.76
2014 Strong A, Patel K, Rader DJ. Sortilin and lipoprotein metabolism: making sense out of complexity. Current Opinion in Lipidology. 25: 350-7. PMID 25101658 DOI: 10.1097/MOL.0000000000000110  0.76
2014 Rader DJ. Spotlight on HDL biology: new insights in metabolism, function, and translation. Cardiovascular Research. 103: 337-40. PMID 25028388 DOI: 10.1093/cvr/cvu164  0.76
2014 Somanathan S, Jacobs F, Wang Q, Hanlon AL, Wilson JM, Rader DJ. AAV vectors expressing LDLR gain-of-function variants demonstrate increased efficacy in mouse models of familial hypercholesterolemia. Circulation Research. 115: 591-9. PMID 25023731 DOI: 10.1161/CIRCRESAHA.115.304008  0.76
2014 Anthanont P, Polisecki E, Asztalos BF, Diffenderfer MR, Barrett PH, Millar JS, Billheimer J, Cuchel M, Rader DJ, Schaefer EJ. A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production. Atherosclerosis. 235: 470-6. PMID 24950002 DOI: 10.1016/j.atherosclerosis.2014.05.935  0.76
2014 Khetarpal SA, Rader DJ. Genetics of lipid traits: Genome-wide approaches yield new biology and clues to causality in coronary artery disease. Biochimica Et Biophysica Acta. 1842: 2010-2020. PMID 24931102 DOI: 10.1016/j.bbadis.2014.06.007  0.76
2014 Chirinos JA, Gurubhagavatula I, Teff K, Rader DJ, Wadden TA, Townsend R, Foster GD, Maislin G, Saif H, Broderick P, Chittams J, Hanlon AL, Pack AI. CPAP, weight loss, or both for obstructive sleep apnea. The New England Journal of Medicine. 370: 2265-75. PMID 24918371 DOI: 10.1056/NEJMoa1306187  0.76
2014 Ding Q, Strong A, Patel KM, Ng SL, Gosis BS, Regan SN, Cowan CA, Rader DJ, Musunuru K. Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing. Circulation Research. 115: 488-92. PMID 24916110 DOI: 10.1161/CIRCRESAHA.115.304351  0.76
2014 Rader DJ. New therapies for coronary artery disease: genetics provides a blueprint. Science Translational Medicine. 6: 239ps4. PMID 24898745 DOI: 10.1126/scitranslmed.3008535  0.76
2014 Javaheri A, Rader DJ. Apolipoprotein A-I and cholesterol efflux: the good, the bad, and the modified. Circulation Research. 114: 1681-3. PMID 24855198 DOI: 10.1161/CIRCRESAHA.114.303974  0.76
2014 Rahman M, Yang W, Akkina S, Alper A, Anderson AH, Appel LJ, He J, Raj DS, Schelling J, Strauss L, Teal V, Rader DJ. Relation of serum lipids and lipoproteins with progression of CKD: The CRIC study. Clinical Journal of the American Society of Nephrology : Cjasn. 9: 1190-8. PMID 24832097 DOI: 10.2215/CJN.09320913  0.76
2014 Yang Y, Kuwano T, Lagor WR, Albert CJ, Brenton S, Rader DJ, Ford DA, Brown RJ. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. Lipids. 49: 505-15. PMID 24777581 DOI: 10.1007/s11745-014-3907-6  0.76
2014 Lassman ME, McAvoy T, Lee AY, Chappell D, Wong O, Zhou H, Reyes-Soffer G, Ginsberg HN, Millar JS, Rader DJ, Gutstein DE, Laterza O. Practical immunoaffinity-enrichment LC-MS for measuring protein kinetics of low-abundance proteins. Clinical Chemistry. 60: 1217-24. PMID 24751376 DOI: 10.1373/clinchem.2014.222455  0.76
2014 Tuteja S, Rader DJ. High-density lipoproteins in the prevention of cardiovascular disease: Changing the paradigm Clinical Pharmacology and Therapeutics. 96: 48-56. PMID 24713591 DOI: 10.1038/clpt.2014.79  0.76
2014 Hancock-Cerutti W, Rader DJ. Opposing effects of ABCG5/8 function on myocardial infarction and gallstone disease. Journal of the American College of Cardiology. 63: 2129-30. PMID 24657684 DOI: 10.1016/j.jacc.2014.02.553  0.76
2014 Rader DJ, Kastelein JJ. Lomitapide and mipomersen: two first-in-class drugs for reducing low-density lipoprotein cholesterol in patients with homozygous familial hypercholesterolemia. Circulation. 129: 1022-32. PMID 24589695 DOI: 10.1161/CIRCULATIONAHA.113.001292  0.76
2014 O'Brien EC, Roe MT, Fraulo ES, Peterson ED, Ballantyne CM, Genest J, Gidding SS, Hammond E, Hemphill LC, Hudgins LC, Kindt I, Moriarty PM, Ross J, Underberg JA, Watson K, ... ... Rader DJ, et al. Rationale and design of the familial hypercholesterolemia foundation CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia registry. American Heart Journal. 167: 342-349.e17. PMID 24576518 DOI: 10.1016/j.ahj.2013.12.008  0.76
2014 Lagor WR, Fields DW, Bauer RC, Crawford A, Abt MC, Artis D, Wherry EJ, Rader DJ. Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis. Atherosclerosis. 233: 234-41. PMID 24529150 DOI: 10.1016/j.atherosclerosis.2013.12.043  0.76
2014 Brown WV, Rader DJ, Goldberg AC. JCL roundtable: drug treatment of severe forms of familial hypercholesterolemia. Journal of Clinical Lipidology. 8: 10-7. PMID 24528683 DOI: 10.1016/j.jacl.2013.09.004  0.76
2014 Javaheri A, Rader DJ, Javaheri S. Statin therapy in heart failure: is it time for a second look? Hypertension. 63: 909-10. PMID 24516102 DOI: 10.1161/HYPERTENSIONAHA.113.02703  0.76
2014 Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, ... ... Rader DJ, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. American Journal of Human Genetics. 94: 223-32. PMID 24507774 DOI: 10.1016/j.ajhg.2014.01.009  0.76
2014 Fruchart JC, Davignon J, Hermans MP, Al-Rubeaan K, Amarenco P, Assmann G, Barter P, Betteridge J, Bruckert E, Cuevas A, Farnier M, Ferrannini E, Fioretto P, Genest J, Ginsberg HN, ... ... Rader DJ, et al. Residual macrovascular risk in 2013: what have we learned? Cardiovascular Diabetology. 13: 26. PMID 24460800 DOI: 10.1186/1475-2840-13-26  0.76
2014 Miksztowicz V, Schreier L, McCoy M, Lucero D, Fassio E, Billheimer J, Rader DJ, Berg G. Role of SN1 lipases on plasma lipids in metabolic syndrome and obesity. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 669-75. PMID 24458708 DOI: 10.1161/ATVBAHA.113.303027  0.76
2014 Rader DJ, deGoma EM. Future of cholesteryl ester transfer protein inhibitors. Annual Review of Medicine. 65: 385-403. PMID 24422575 DOI: 10.1146/annurev-med-050311-163305  0.76
2014 Mehta NN, Matthews GJ, Krishnamoorthy P, Shah R, McLaughlin C, Patel P, Budoff M, Chen J, Wolman M, Go A, He J, Kanetsky PA, Master SR, Rader DJ, Raj D, et al. Higher plasma CXCL12 levels predict incident myocardial infarction and death in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort study. European Heart Journal. 35: 2115-22. PMID 24306482 DOI: 10.1093/eurheartj/eht481  0.76
2013 Larach DB, Cuchel M, Rader DJ. Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics. Clinical Lipidology. 8: 635-648. PMID 25374625 DOI: 10.2217/clp.13.73  0.76
2013 Brown WV, Rader DJ, Kane J. JCL Roundtable: diagnosis of severe familial hypercholesterolemia. Journal of Clinical Lipidology. 7: 540-5. PMID 24314353 DOI: 10.1016/j.jacl.2013.08.003  0.76
2013 Javaheri A, Rader DJ. High-density lipoprotein: NO failure in heart failure. Circulation Research. 113: 1275-7. PMID 24311613 DOI: 10.1161/CIRCRESAHA.113.302667  0.76
2013 Hurt-Camejo E, Gautier T, Rosengren B, Dikkers A, Behrendt M, Grass DS, Rader DJ, Tietge UJ. Expression of type IIA secretory phospholipase A2 inhibits cholesteryl ester transfer protein activity in transgenic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2707-14. PMID 24115030 DOI: 10.1161/ATVBAHA.113.301410  0.76
2013 Toth PP, Barter PJ, Rosenson RS, Boden WE, Chapman MJ, Cuchel M, D'Agostino RB, Davidson MH, Davidson WS, Heinecke JW, Karas RH, Kontush A, Krauss RM, Miller M, Rader DJ. High-density lipoproteins: a consensus statement from the National Lipid Association. Journal of Clinical Lipidology. 7: 484-525. PMID 24079290 DOI: 10.1016/j.jacl.2013.08.001  0.76
2013 Stitziel NO, Fouchier SW, Sjouke B, Peloso GM, Moscoso AM, Auer PL, Goel A, Gigante B, Barnes TA, Melander O, Orho-Melander M, Duga S, Sivapalaratnam S, Nikpay M, Martinelli N, ... ... Rader DJ, et al. Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2909-14. PMID 24072694 DOI: 10.1161/ATVBAHA.113.302426  0.76
2013 Chen SJ, Sanmiguel J, Lock M, McMenamin D, Draper C, Limberis MP, Kassim SH, Somanathan S, Bell P, Johnston JC, Rader DJ, Wilson JM. Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia. Human Gene Therapy. Clinical Development. 24: 154-60. PMID 24070336 DOI: 10.1089/humc.2013.082  0.76
2013 Lagor WR, Johnston JC, Lock M, Vandenberghe LH, Rader DJ. Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism. Methods in Molecular Biology (Clifton, N.J.). 1027: 273-307. PMID 23912992 DOI: 10.1007/978-1-60327-369-5_13  0.76
2013 Keenan TE, Rader DJ. Genetics of lipid traits and relationship to coronary artery disease. Current Cardiology Reports. 15: 396. PMID 23881580 DOI: 10.1007/s11886-013-0396-9  0.76
2013 Khera AV, Rader DJ. Cholesterol efflux capacity: full steam ahead or a bump in the road? Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1449-51. PMID 23766382 DOI: 10.1161/ATVBAHA.113.301519  0.76
2013 Vickers KC, Rader DJ. Nuclear receptors and microRNA-144 coordinately regulate cholesterol efflux. Circulation Research. 112: 1529-31. PMID 23743223 DOI: 10.1161/CIRCRESAHA.113.301422  0.76
2013 Ferguson JF, Matthews GJ, Townsend RR, Raj DS, Kanetsky PA, Budoff M, Fischer MJ, Rosas SE, Kanthety R, Rahman M, Master SR, Qasim A, Li M, Mehta NN, Shen H, ... ... Rader DJ, et al. Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort). Journal of the American College of Cardiology. 62: 789-98. PMID 23727086 DOI: 10.1016/j.jacc.2013.01.103  0.76
2013 Tatematsu S, Francis SA, Natarajan P, Rader DJ, Saghatelian A, Brown JD, Michel T, Plutzky J. Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1788-94. PMID 23723371 DOI: 10.1161/ATVBAHA.113.301300  0.76
2013 Picataggi A, Lim GF, Kent AP, Millar JS, Rader DJ, Stylianou IM. A coding variant in SR-BI (I179N) significantly increases atherosclerosis in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 257-65. PMID 23722970 DOI: 10.1007/s00335-013-9459-x  0.76
2013 Zhou H, Castro-Perez J, Lassman ME, Thomas T, Li W, McLaughlin T, Dan X, Jumes P, Wagner JA, Gutstein DE, Hubbard BK, Rader DJ, Millar JS, Ginsberg HN, Reyes-Soffer G, et al. Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 27: 1294-302. PMID 23681806 DOI: 10.1002/rcm.6572  0.76
2013 Kahn ML, Rader DJ. Lymphatics as a new active player in reverse cholesterol transport. Cell Metabolism. 17: 627-8. PMID 23663731 DOI: 10.1016/j.cmet.2013.04.017  0.76
2013 Cuchel M, Rader DJ. Microsomal transfer protein inhibition in humans. Current Opinion in Lipidology. 24: 246-50. PMID 23594709 DOI: 10.1097/MOL.0b013e32836139df  0.76
2013 Cuchel M, Rader DJ. Lipid-lowering treatment for homozygous familial hypercholesterolaemia--authors' reply. Lancet (London, England). 381: 1183. PMID 23561998 DOI: 10.1016/S0140-6736(13)60798-9  0.76
2013 Bose S, Krishnamoorthy P, Varanasi A, Nair J, Schutta M, Braunstein S, Iqbal N, Schwartz S, St Clair C, Master SR, Rader DJ, Reilly MP, Mehta NN. Measurement of waist circumference predicts coronary atherosclerosis beyond plasma adipokines. Obesity (Silver Spring, Md.). 21: E118-23. PMID 23505191 DOI: 10.1002/oby.20086  0.76
2013 Master SR, Rader DJ. Beyond LDL cholesterol in assessing cardiovascular risk: apo B or LDL-P? Clinical Chemistry. 59: 723-5. PMID 23487171 DOI: 10.1373/clinchem.2013.203208  0.76
2013 Agarwala A, Billheimer J, Rader DJ. Atherosclerosis: Mighty minipig in fight against cardiovascular disease Science Translational Medicine. 5. PMID 23283365 DOI: 10.1126/scitranslmed.3005369  0.76
2013 Cuchel M, Rader DJ. Authors' reply The Lancet. 381: 1183.  0.76
2012 Qamar A, Rader DJ. Effect of interleukin 1β inhibition in cardiovascular disease Current Opinion in Lipidology. 23: 548-553. PMID 23069985 DOI: 10.1097/MOL.0b013e328359b0a6  0.76
2012 Rader DJ, DeGoma EM. Approach to the patient with extremely low HDL-cholesterol Journal of Clinical Endocrinology and Metabolism. 97: 3399-3407. PMID 23043194 DOI: 10.1210/jc.2012-2185  0.76
2012 Rader DJ, Tall AR. The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis? Nature Medicine. 18: 1344-6. PMID 22961164 DOI: 10.1038/nm.2937  0.76
2012 Degoma EM, Rader DJ. High-density lipoprotein particle number: A better measure to quantify high-density lipoprotein? Journal of the American College of Cardiology. 60: 517-520. PMID 22796252 DOI: 10.1016/j.jacc.2012.03.058  0.76
2012 Strong A, Ding Q, Edmondson AC, Millar JS, Sachs KV, Li X, Kumaravel A, Wang MY, Ai D, Guo L, Alexander ET, Nguyen D, Lund-Katz S, Phillips MC, Morales CR, ... ... Rader DJ, et al. Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. The Journal of Clinical Investigation. 122: 2807-16. PMID 22751103 DOI: 10.1172/JCI63563  0.76
2012 Strong A, Rader DJ. Sortilin as a regulator of lipoprotein metabolism. Current Atherosclerosis Reports. 14: 211-8. PMID 22538429 DOI: 10.1007/s11883-012-0248-x  0.76
2012 Rader DJ, Parmacek MS. Secreted miRNAs suppress atherogenesis Nature Cell Biology. 14: 233-235. PMID 22373869 DOI: 10.1038/ncb2452  0.76
2012 Rader DJ. IL-1 and atherosclerosis: A murine twist to an evolving human story Journal of Clinical Investigation. 122: 27-30. PMID 22201674 DOI: 10.1172/JCI61163  0.76
2012 He J, Li H, Edmondson AC, Rader DJ, Li M. A Gaussian copula approach for the analysis of secondary phenotypes in case-control genetic association studies. Biostatistics (Oxford, England). 13: 497-508. PMID 21933777 DOI: 10.1093/biostatistics/kxr025  0.76
2012 Nakaya K, Ikewaki K, Rader DJ. HDL, ABC transporters, and cholesterol efflux as therapeutic targets in atherosclerosis Atherosclerosis: Treatment and Prevention. 169-184. DOI: 10.4032/9789814364263  0.76
2012 Tuteja S, Rader DJ. Genomic medicine in the prevention and treatment of atherosclerotic cardiovascular disease Personalized Medicine. 9: 395-404. DOI: 10.2217/pme.12.34  0.76
2011 Wang K, Edmondson AC, Li M, Gao F, Qasim AN, Devaney JM, Burnett MS, Waterworth DM, Mooser V, Grant SF, Epstein SE, Reilly MP, Hakonarson H, Rader DJ. Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation. Frontiers in Genetics. 2: 41. PMID 22303337 DOI: 10.3389/fgene.2011.00041  0.76
2011 Khetarpal SA, Edmondson AC, Raghavan A, Neeli H, Jin W, Badellino KO, Demissie S, Manning AK, DerOhannessian SL, Wolfe ML, Cupples LA, Li M, Kathiresan S, Rader DJ. Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol. Plos Genetics. 7: e1002393. PMID 22174694 DOI: 10.1371/journal.pgen.1002393  0.76
2011 Mehta NN, Rader DJ. Fluorescent green plaques: Light at the end of the catheter? Cell Metabolism. 14: 7-8. PMID 21723499 DOI: 10.1016/j.cmet.2011.06.005  0.76
2011 Rak K, Rader DJ. Cardiovascular disease: The diet-microbe morbid union Nature. 472: 40-41. PMID 21475185 DOI: 10.1038/472040a  0.76
2011 Edmondson AC, Braund PS, Stylianou IM, Khera AV, Nelson CP, Wolfe ML, Derohannessian SL, Keating BJ, Qu L, He J, Tobin MD, Tomaszewski M, Baumert J, Klopp N, Döring A, ... ... Rader DJ, et al. Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol. Circulation. Cardiovascular Genetics. 4: 145-55. PMID 21303902 DOI: 10.1161/CIRCGENETICS.110.957563  0.76
2011 Degoma EM, Rader DJ. Novel HDL-directed pharmacotherapeutic strategies Nature Reviews Cardiology. 8: 266-277. PMID 21243009 DOI: 10.1038/nrcardio.2010.200  0.76
2011 Lagor WR, Rader DJ. Phospholipidation of HDL-how much is too much? Clinical Chemistry. 57: 4-6. PMID 21078838 DOI: 10.1373/clinchem.2010.156224  0.76
2011 He J, Wang K, Edmondson AC, Rader DJ, Li C, Li M. Gene-based interaction analysis by incorporating external linkage disequilibrium information. European Journal of Human Genetics : Ejhg. 19: 164-72. PMID 20924406 DOI: 10.1038/ejhg.2010.164  0.76
2011 Toh SA, Levin M, Rader DJ. Atherogenic lipid metabolism in obesity Metabolic Basis of Obesity. 293-309. DOI: 10.1007/978-1-4419-1607-5_15  0.76
2011 Khera AV, Cuchel M, Rader DJ. To authors reply New England Journal of Medicine. 364: 1474-1475.  0.76
2010 Kassim SH, Wilson JM, Rader DJ. Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies. Clinical Lipidology. 5: 793-809. PMID 22505953 DOI: 10.2217/clp.10.73  0.76
2010 Strong A, Rader DJ. Clinical Implications of Lipid Genetics for Cardiovascular Disease. Current Cardiovascular Risk Reports. 4: 461-468. PMID 21853159 DOI: 10.1007/s12170-010-0131-7  0.76
2010 Yasuda T, Ishida T, Rader DJ. Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis. Circulation Journal : Official Journal of the Japanese Circulation Society. 74: 2263-70. PMID 20962428 DOI: JST.JSTAGE/circj/CJ-10-0934  0.76
2010 Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, ... ... Rader DJ, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 466: 707-13. PMID 20686565 DOI: 10.1038/nature09270  0.76
2010 Khera AV, Rader DJ. Future therapeutic directions in reverse cholesterol transport Current Atherosclerosis Reports. 12: 73-81. PMID 20425274 DOI: 10.1007/s11883-009-0080-0  0.76
2010 Shah A, Rader DJ, Millar JS. The effect of PPAR-α agonism on apolipoprotein metabolism in humans Atherosclerosis. 210: 35-40. PMID 20005515 DOI: 10.1016/j.atherosclerosis.2009.11.010  0.76
2010 Kathiresan S, Rader DJ. Lipoprotein Disorders Essentials of Genomic and Personalized Medicine. 269-288. DOI: 10.1016/B978-0-12-374934-5.00023-4  0.76
2009 Khera AV, Rader DJ. Discovery and Validation of New Molecular Targets in Treating Dyslipidemia: The Role of Human Genetics Trends in Cardiovascular Medicine. 19: 195-201. PMID 20211435 DOI: 10.1016/j.tcm.2009.12.003  0.76
2009 Rader DJ. Lecithin: Cholesterol acyltransferase and atherosclerosis: Another high-density lipoprotein story that doesn't quite follow the script Circulation. 120: 549-552. PMID 19652089 DOI: 10.1161/CIRCULATIONAHA.109.881979  0.76
2009 Duffy D, Rader DJ. Update on strategies to increase HDL quantity and function Nature Reviews. Cardiology. 6: 455-463. PMID 19488077 DOI: 10.1038/nrcardio.2009.94  0.76
2009 Brown RJ, Edmondson AC, Griffon N, Hill TB, Fuki IV, Badellino KO, Li M, Wolfe ML, Reilly MP, Rader DJ. A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis. Journal of Lipid Research. 50: 1910-6. PMID 19411705 DOI: 10.1194/jlr.P900020-JLR200  0.76
2009 Jensen MK, Rimm EB, Mukamal KJ, Edmondson AC, Rader DJ, Vogel U, Tjønneland A, Sørensen TI, Schmidt EB, Overvad K. The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. European Heart Journal. 30: 1584-9. PMID 19411665 DOI: 10.1093/eurheartj/ehp145  0.76
2009 Edmondson AC, Brown RJ, Kathiresan S, Cupples LA, Demissie S, Manning AK, Jensen MK, Rimm EB, Wang J, Rodrigues A, Bamba V, Khetarpal SA, Wolfe ML, Derohannessian S, Li M, ... ... Rader DJ, et al. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. The Journal of Clinical Investigation. 119: 1042-50. PMID 19287092 DOI: 10.1172/JCI37176  0.76
2009 Neeli H, Gadi R, Rader DJ. Managing diabetic dyslipidemia: Beyond statin therapy Current Diabetes Reports. 9: 11-17. PMID 19192419 DOI: 10.1007/s11892-009-0004-y  0.76
2009 Movva R, Rader DJ. [Laboratory assessment of HDL heterogeneity and function]. Annales De Biologie Clinique. 67: 7-21. PMID 19189882 DOI: 10.1684/abc.2008.0284  0.76
2009 Gordon RY, Becker DJ, Rader DJ. Reduced efficacy of rosuvastatin by St. John's Wort. The American Journal of Medicine. 122: e1-2. PMID 19185075 DOI: 10.1016/j.amjmed.2008.09.033  0.76
2009 Bays HE, Rader DJ. Does nicotinic acid (niacin) lower blood pressure? International Journal of Clinical Practice. 63: 151-159. PMID 19054161 DOI: 10.1111/j.1742-1241.2008.01934.x  0.76
2009 Rader DJ. Therapeutic Targeting of High-Density Lipoprotein Metabolism Clinical Lipidology: a Companion to Braunwald's Heart Disease. 544-552. DOI: 10.1016/B978-141605469-6.50049-4  0.76
2008 Edmondson AC, Rader DJ. Genome-wide approaches to finding novel genes for lipid traits: the start of a long road. Circulation. Cardiovascular Genetics. 1: 3-6. PMID 20031536 DOI: 10.1161/CIRCGENETICS.108.815530  0.76
2008 Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, ... ... Rader DJ, et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. Plos One. 3: e3583. PMID 18974833 DOI: 10.1371/journal.pone.0003583  0.76
2008 Neeli H, Rader DJ. Cholesteryl Ester Transfer Protein (CETP) Inhibitors: Is There Life After Torcetrapib? Cardiology Clinics. 26: 537-546. PMID 18929230 DOI: 10.1016/j.ccl.2008.06.005  0.76
2008 Toh SA, Rader DJ. Dyslipidemia in insulin resistance: Clinical challenges and adipocentric therapeutic frontiers Expert Review of Cardiovascular Therapy. 6: 1007-1022. PMID 18666851 DOI: 10.1586/14779072.6.7.1007  0.76
2008 Brown RJ, Rader DJ. When HDL gets fat.. Circulation Research. 103: 131-132. PMID 18635830 DOI: 10.1161/CIRCRESAHA.108.180638  0.76
2008 Hunter DJ, Altshuler D, Rader DJ. From Darwin's finches to canaries in the coal mine--mining the genome for new biology. The New England Journal of Medicine. 358: 2760-3. PMID 18579810 DOI: 10.1056/NEJMp0804318  0.76
2008 Movva R, Rader DJ. Laboratory assessment of HDL heterogeneity and function. Clinical Chemistry. 54: 788-800. PMID 18375481 DOI: 10.1373/clinchem.2007.101923  0.76
2008 Rader DJ, Daugherty A. Translating molecular discoveries into new therapies for atherosclerosis Nature. 451: 904-913. PMID 18288179 DOI: 10.1038/nature06796  0.76
2008 Glassberg H, Rader DJ. Management of lipids in the prevention of cardiovascular events Annual Review of Medicine. 59: 79-94. PMID 17937591 DOI: 10.1146/annurev.med.59.121206.112237  0.76
2008 Rader DJ. Therapeutic Targeting of High-Density Lipoproteins High-Density Lipoproteins: From Basic Biology to Clinical Aspects. 507-522. DOI: 10.1002/9783527625178.ch21  0.76
2008 Rader DJ. The editorialist replies New England Journal of Medicine. 358: 1864.  0.76
2007 Brown RJ, Rader DJ. Lipases as modulators of atherosclerosis in murine models Current Drug Targets. 8: 1307-1319. PMID 18220707 DOI: 10.2174/138945007783220614  0.76
2007 Rader DJ. Liver X Receptor and Farnesoid X Receptor as Therapeutic Targets American Journal of Cardiology. 100. PMID 18047847 DOI: 10.1016/j.amjcard.2007.08.008  0.76
2007 Cuchel M, Rader DJ. Is the Cholesteryl Ester Transfer Protein Proatherogenic or Antiatherogenic in Humans?**Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology Journal of the American College of Cardiology. 50: 1956-1958. PMID 17996560 DOI: 10.1016/j.jacc.2007.07.059  0.76
2007 Lilly SM, Rader DJ. New targets and emerging therapies for reducing LDL cholesterol Current Opinion in Lipidology. 18: 650-655. PMID 17993811 DOI: 10.1097/MOL.0b013e3282f169c6  0.76
2007 Rader DJ. Illuminating HDL - Is it still a viable therapeutic target? New England Journal of Medicine. 357: 2180-2183. PMID 17984168 DOI: 10.1056/NEJMe0707210  0.76
2007 Rader DJ, Ischiropoulos H. 'Multipurpose oxidase' in atherogenesis. Nature Medicine. 13: 1146-7. PMID 17917660 DOI: 10.1038/nm1007-1146b  0.76
2007 Wang X, Rader DJ. Molecular regulation of macrophage reverse cholesterol transport Current Opinion in Cardiology. 22: 368-372. PMID 17556891 DOI: 10.1097/HCO.0b013e3281ec5113  0.76
2007 Bamba V, Rader DJ. Obesity and Atherogenic Dyslipidemia Gastroenterology. 132: 2181-2190. PMID 17498511 DOI: 10.1053/j.gastro.2007.03.056  0.76
2007 Wang X, Jin W, Rader DJ. Upregulation of macrophage endothelial lipase by toll-like receptors 4 and 3 modulates macrophage interleukin-10 and -12 production Circulation Research. 100: 1008-1015. PMID 17347473 DOI: 10.1161/01.RES.0000263011.34709.c5  0.76
2007 Rader DJ. Effect of Insulin Resistance, Dyslipidemia, and Intra-abdominal Adiposity on the Development of Cardiovascular Disease and Diabetes Mellitus American Journal of Medicine. 120. PMID 17320517 DOI: 10.1016/j.amjmed.2007.01.003  0.76
2007 Rader DJ. Mechanisms of Disease: HDL metabolism as a target for novel therapies Nature Clinical Practice Cardiovascular Medicine. 4: 102-109. PMID 17245404 DOI: 10.1038/ncpcardio0768  0.76
2007 Cuchel M, Rader DJ. The authors reply [2] New England Journal of Medicine. 356: 1779-1780. DOI: 10.1056/NEJMc070300  0.76
2006 Rader DJ. Molecular regulation of HDL metabolism and function: Implications for novel therapies Journal of Clinical Investigation. 116: 3090-3100. PMID 17143322 DOI: 10.1172/JCI30163  0.76
2006 Cuchel M, Rader DJ. Macrophage reverse cholesterol transport: Key to the regression of atherosclerosis? Circulation. 113: 2548-2555. PMID 16735689 DOI: 10.1161/CIRCULATIONAHA.104.475715  0.76
2006 Reilly M, Rader DJ. Apolipoprotein E and coronary disease: A puzzling paradox Plos Medicine. 3: 0736-0738. PMID 16729847 DOI: 10.1371/journal.pmed.0030258  0.76
2006 Duffy D, Rader DJ. High-density lipoprotein cholesterol therapies: The next frontier in lipid management Journal of Cardiopulmonary Rehabilitation. 26: 1-8. PMID 16617219 DOI: 10.1097/00008483-200601000-00001  0.76
2006 Duffy D, Rader DJ. Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport Circulation. 113: 1140-1150. PMID 16505192 DOI: 10.1161/CIRCULATIONAHA.105.593855  0.76
2005 Rader DJ. Gain-of-function mutations and therapeutic implications: Lipoprotein lipase S447X to the rescue Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2018-2019. PMID 16199757 DOI: 10.1161/01.ATV.0000183606.81315.85  0.76
2005 Dunbar RL, Rader DJ. Demystifying triglycerides: A practical approach for the clinician Cleveland Clinic Journal of Medicine. 72: 661-680. PMID 16122052  0.76
2005 Rader DJ, Puré E. Lipoproteins, macrophage function, and atherosclerosis: Beyond the foam cell? Cell Metabolism. 1: 223-230. PMID 16054067 DOI: 10.1016/j.cmet.2005.03.005  0.76
2005 Broedl UC, Rader DJ. Gene therapy for lipoprotein disorders Expert Opinion On Biological Therapy. 5: 1029-1038. PMID 16050781 DOI: 10.1517/14712598.5.8.1029  0.76
2005 Lewis GF, Rader DJ. New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circulation Research. 96: 1221-32. PMID 15976321 DOI: 10.1161/01.RES.0000170946.56981.5c  0.76
2005 Duffy D, Rader DJ. Drugs in development: Targeting high-density lipoprotein metabolism and reverse cholesterol transport Current Opinion in Cardiology. 20: 301-306. PMID 15956827 DOI: 10.1097/01.hco.0000168532.69342.26  0.76
2005 Ky B, Rader DJ. The effects of statin therapy on plasma markers of inflammation in patients without vascular disease Clinical Cardiology. 28: 67-70. PMID 15757075  0.76
2005 Rader DJ. ATVB in focus novel approaches to the treatment of dyslipidemia Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 480-481. PMID 15731488 DOI: 10.1161/01.ATV.0000154483.28595.a3  0.76
2005 Rader DJ. Gene therapy for genetic lipid disorders: Lipoprotein lipase deficiency as a paradigm Netherlands Journal of Medicine. 63: 2-3. PMID 15719845  0.76
2005 Dunbar RL, Rader DJ. Current drug options for raising HDL cholesterol Current Treatment Options in Cardiovascular Medicine. 7: 15-23.  0.76
2004 Wolfe ML, Rader DJ. Cholesteryl ester transfer protein and coronary artery disease: An observation with therapeutic implications Circulation. 110: 1338-1340. PMID 15364817 DOI: 10.1161/01.CIR.0000143047.52724.BB  0.76
2004 Szapary PO, Rader DJ. The triglyceride-high-density lipoprotein axis: An important target of therapy? American Heart Journal. 148: 211-221. PMID 15308990 DOI: 10.1016/j.ahj.2004.03.037  0.76
2004 Rader DJ. Inhibition of cholesteryl ester transfer protein activity: A new therapeutic approach to raising high-density lipoprotein Current Atherosclerosis Reports. 6: 398-405. PMID 15296707  0.76
2004 Dunbar RL, Rader DJ. Slaying the metabolic syndrome. Are we battling the Hydra or the Chimera? Minerva Endocrinologica. 29: 89-111. PMID 15282443  0.76
2004 Broedl UC, Jin W, Rader DJ. Endothelial lipase: A modulator of lipoprotein metabolism upregulated by inflammation Trends in Cardiovascular Medicine. 14: 202-206. PMID 15261893 DOI: 10.1016/j.tcm.2004.03.003  0.76
2004 Badellino KO, Rader DJ. The role of endothelial lipase in high-density lipoprotein metabolism Current Opinion in Cardiology. 19: 392-395. PMID 15218402 DOI: 10.1097/01.hco.0000130161.89169.02  0.76
2004 Jacoby DS, Mohler ER, Rader DJ. Noninvasive atherosclerosis imaging for predicting cardiovascular events and assessing therapeutic interventions Current Atherosclerosis Reports. 6: 20-26. PMID 14662104  0.76
2004 Dunbar RL, Rader DJ. Therapeutic strategies for the treatment of dyslipidemia Drug Discovery Today: Therapeutic Strategies. 1: 169-176. DOI: 10.1016/j.ddstr.2004.09.003  0.76
2003 Rader DJ. High-Density Lipoproteins as an Emerging Therapeutic Target for Atherosclerosis Journal of the American Medical Association. 290: 2322-2324. PMID 14600193 DOI: 10.1001/jama.290.17.2322  0.76
2003 Cuchel M, Rader DJ. Genetics of increased HDL cholesterol levels: Insights into the relationship between HDL metabolism and atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1710-1712. PMID 14555638 DOI: 10.1161/01.ATV.0000092947.15939.93  0.76
2003 Reilly MP, Rader DJ. The metabolic syndrome: More than the sum of its parts? Circulation. 108: 1546-1551. PMID 14517150 DOI: 10.1161/01.CIR.0000088846.10655.E0  0.76
2003 Rader DJ. Regulation of reverse cholesterol transport and clinical implications The American Journal of Cardiology. 92. PMID 12957326  0.76
2003 Rader DJ, Cohen J, Hobbs HH. Monogenic hypercholesterolemia: New insights in pathogenesis and treatment Journal of Clinical Investigation. 111: 1795-1803. PMID 12813012 DOI: 10.1172/JCI200318925  0.76
2003 Jacoby DS, Rader DJ. Renin-angiotensin system and atherothrombotic disease: From genes to treatment Archives of Internal Medicine. 163: 1155-1164. PMID 12767951 DOI: 10.1001/archinte.163.10.1155  0.76
2003 Rader DJ. Effects of nonstatin lipid drug therapy on high-density lipoprotein metabolism American Journal of Cardiology. 91. PMID 12679199 DOI: 10.1016/S0002-9149(02)03384-2  0.76
2003 Rader DJ. Therapy to reduce risk of coronary heart disease Clinical Cardiology. 26: 2-8. PMID 12539806  0.76
2003 Rader DJ. Interrelationships between the metabolic syndrome, inflammation, and HDL metabolism Cardiology Review. 20: 12-15.  0.76
2002 Cuchel M, Rader DJ. The role of high density lipoproteins in thrombosis Thescientificworldjournal [Electronic Resource]. 2: 89-95. PMID 12806041  0.76
2002 Rader DJ. High-density lipoproteins and atherosclerosis American Journal of Cardiology. 90. PMID 12419482  0.76
2002 Epstein JA, Rader DJ, S.parmacek M. Perspective: Cardiovascular disease in the postgenomic era - Lessons learned and challenges ahead Endocrinology. 143: 2045-2050. PMID 12021168 DOI: 10.1210/en.143.6.2045  0.76
2002 Jin W, Marchadier D, Rader DJ. Lipases and HDL metabolism Trends in Endocrinology and Metabolism. 13: 174-178. PMID 11943562  0.76
2002 Rader DJ. Future outlook: changing perspectives on best practice The American Journal of Managed Care. 8. PMID 11855702  0.76
2002 Rader DJ. Protective effects of HDL-C and need to raise low levels explored The American Journal of Managed Care. PMID 11833453  0.76
2002 Rader DJ, Stein, Rudel, Turley, Brewer. Issues in cholesterol management Cardiology Review. 19: 29-31.  0.76
2001 Rader DJ. Gene therapy for familial hypercholesterolemia Nutrition, Metabolism and Cardiovascular Diseases. 11: 40-44. PMID 12063775  0.76
2001 Rader DJ. A new feature on the cholesterol-lowering landscape Nature Medicine. 7: 1282-1284. PMID 11726962 DOI: 10.1038/nm1201-1282  0.76
2001 Szapary PO, Rader DJ. Pharmacological management of high triglycerides and low high-density lipoproetin cholesterol Current Opinion in Pharmacology. 1: 113-120. PMID 11714084 DOI: 10.1016/S1471-4892(01)00028-5  0.76
2001 Meagher E, Rader DJ. Antioxidant therapy and atherosclerosis: Animal and human studies Trends in Cardiovascular Medicine. 11: 162-165. PMID 11686007 DOI: 10.1016/S1050-1738(01)00105-0  0.76
2001 Thompson PD, Rader DJ. Does exercise increase HDL cholesterol in those who need it the most? Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1097-1098. PMID 11451735  0.76
2001 Reilly MP, Rader DJ. Clinical decision-making in the management of lipid disorders Disease Management and Clinical Outcomes. 3: 30-37.  0.76
2001 Rader DJ, Rosas S. Management of selected lipid abnormalities: Hypertriglyceridemia, low HDL cholesterol, lipoprotein(a), in thyroid and renal diseases, and post-transplantation Cardiology Clinics. 19: 311-325.  0.76
2000 Rader DJ, Dugi KA. The endothelium and lipoproteins: Insights from recent cell biology and animal studies Seminars in Thrombosis and Hemostasis. 26: 521-528. PMID 11129408  0.76
2000 Dugi KA, Rader DJ. Lipoproteins and the endothelium: Insights from clinical research Seminars in Thrombosis and Hemostasis. 26: 513-519. PMID 11129407  0.76
2000 Kawashiri MA, Maugeais C, Rader DJ. High-density lipoprotein metabolism: molecular targets for new therapies for atherosclerosis Current Atherosclerosis Reports. 2: 363-372. PMID 11122767  0.76
2000 Rader DJ. Inflammatory markers of coronary risk New England Journal of Medicine. 343: 1179-1182. PMID 11036126 DOI: 10.1056/NEJM200010193431609  0.76
2000 Rader DJ. Role of coronary calcification assessment: Overview Journal of Cardiovascular Risk. 7: 89-91. PMID 10879410  0.76
2000 Rader DJ, Puré E. Genetic susceptibility to atherosclerosis insights from mice Circulation Research. 86: 1013-1015. PMID 10827128  0.76
2000 Rader DJ, Jaye M. Endothelial lipase: A new member of the triglyceride lipase gene family Current Opinion in Lipidology. 11: 141-147. PMID 10787175 DOI: 10.1097/00041433-200004000-00006  0.76
2000 Rader DJ, Maugeais C. Genes influencing HDL metabolism: New perspectives and implications for atherosclerosis prevention Molecular Medicine Today. 6: 170-175. PMID 10740256 DOI: 10.1016/S1357-4310(00)01673-7  0.76
2000 Rader DJ, Rosas S. Management of selected lipid abnormalities: Hypertriglyceridemia, low HDL cholesterol, lipoprotein(a), in thyroid and renal diseases, and post- transplantation Medical Clinics of North America. 84: 43-61. PMID 10685127  0.76
2000 Kawashiri MA, Rader DJ. Gene therapy for lipid disorders Current Controlled Trials in Cardiovascular Medicine. 1: 120-127. DOI: 10.1186/CVM-1-2-120  0.76
2000 Rader DJ. Role of coronary calcification scanning in risk factor assessment European Journal of Preventive Cardiology. 7: 89-91. DOI: 10.1177/204748730000700201  0.76
2000 Mohler ER, Rader DJ. Lipoprotein(a): A molecular vignette of an evolving risk factor Acc Current Journal Review. 9: 37-38. DOI: 10.1016/S1062-1458(00)00156-2  0.76
2000 Kirschner R, Rader DJ. Variations in cholesterol values Consultant. 40: 2009.  0.76
1999 Rader DJ, Tietge UJ. Gene therapy for dyslipidemia: clinical prospects Current Atherosclerosis Reports. 1: 58-69. PMID 11122693  0.76
1999 Hobbs HH, Rader DJ. ABC1: Connecting yellow tonsils, neuropathy, and very low HDL Journal of Clinical Investigation. 104: 1015-1017. PMID 10525038  0.76
1999 Rader DJ. Noninvasive procedures for subclinical atherosclerosis risk assessment American Journal of Medicine. 107: 25-27. PMID 10484235 DOI: 10.1016/S0002-9343(99)00142-4  0.76
1999 Friedrich CA, Rader DJ. Management of lipid disorders Rheumatic Disease Clinics of North America. 25: 507-520. PMID 10467626 DOI: 10.1016/S0889-857X(05)70084-3  0.76
1999 Rader DJ, Haffner SM. Role of fibrates in the management of hypertriglyceridemia American Journal of Cardiology. 83. PMID 10357573  0.76
1999 Rader DJ. Pathophysiology and management of low high-density lipoprotein cholesterol American Journal of Cardiology. 83. PMID 10357571  0.76
1999 Mohler ER, Rader DJ. Clinical utility of coronary calcification scanning in primary prevention Acc Current Journal Review. 8: 76-78. DOI: 10.1016/S1062-1458(99)00039-2  0.76
1998 Rader DJ. Atherosclerosis, Acute Coronary Events, and Cholesterol-Lowering: A New Paradigm Value in Health. 1: 101-104. PMID 16674355  0.76
1998 Rader DJ, FitzGerald GA. State of the art: atherosclerosis in a limited edition. Nature Medicine. 4: 899-900. PMID 9701240 DOI: 10.1038/nm0898-899  0.76
1998 Kindy MS, Rader DJ. Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice American Journal of Pathology. 152: 1387-1395. PMID 9588907  0.76
1998 Rader DJ. Mechanisms of acute coronary events American Journal of Managed Care. 4.  0.76
1997 Rader DJ. Gene therapy for atherosclerosis International Journal of Clinical and Laboratory Research. 27: 35-43. PMID 9144025  0.76
1996 Rader DJ, Ikewaki K. Unravelling high density lipoprotein-apolipoprotein metabolism in human mutants and animal models Current Opinion in Lipidology. 7: 117-123. PMID 8818507  0.76
1995 Jamieson DG, Usher DC, Rader DJ, Lavi E. Apolipoprotein(a) deposition in atherosclerotic plaques of cerebral vessels. A potential role for endothelial cells in lesion formation. The American Journal of Pathology. 147: 1567-74. PMID 7495281  0.76
1994 Rader DJ, Hoeg JM, Brewer HB. Quantitation of plasma apolipoproteins in the primary and secondary prevention of coronary artery disease Annals of Internal Medicine. 120: 1012-1025. PMID 8185133  0.76
1994 Rader DJ. Low HDL and coronary heart disease Biomedicine and Pharmacotherapy. 48: 175.  0.76
1993 Rader DJ, Brewer HB. Abetalipoproteinemia: New Insights Into Lipoprotein Assembly and Vitamin E Metabolism From a Rare Genetic Disease Jama: the Journal of the American Medical Association. 270: 865-869. PMID 8340987 DOI: 10.1001/jama.1993.03510070087042  0.76
1992 Rader DJ, Brewer HB. Lipoprotein(a): Clinical Approach to a Unique Atherogenic Lipoprotein Jama: the Journal of the American Medical Association. 267: 1109-1112. PMID 1531241 DOI: 10.1001/jama.1992.03480080079031  0.76
1992 Lohse P, Rader DJ, Brewer HB. Heterozygosity for apolipoprotein E-4Philadelphia(Glu13 → lys, arg145 → Cys) is associated with incomplete dominance of type III hyperlipoproteinemia Journal of Biological Chemistry. 267: 13642-13646. PMID 1352296  0.76
1992 Schaefer JR, Rader DJ, Brewer HB. Investigation of lipoprotein kinetics using endogenous labeling with stable isotopes Current Opinion in Lipidology. 3: 227-232. DOI: 10.1097/00041433-199206000-00011  0.76
1991 Bryan Brewer H, Rader DJ. HDL: Structure, function and metabolism Progress in Lipid Research. 30: 139-144. PMID 1823933 DOI: 10.1016/0163-7827(91)90009-T  0.76
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