| Year |
Citation |
Score |
| 2024 |
Majer AD, Hua X, Katona BW. Menin in Cancer. Genes. 15. PMID 39336822 DOI: 10.3390/genes15091231 |
0.362 |
|
| 2023 |
Nyul TE, Beyries K, Hojnacki T, Glynn R, Paulosky KE, Gedela A, Majer A, Altman L, Buckley KH, Feng Z, Sun K, Peng Z, Tobias JW, Hua X, Katona BW. Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription. Cancers. 15. PMID 37627154 DOI: 10.3390/cancers15164126 |
0.301 |
|
| 2020 |
Katona BW, Hojnacki T, Glynn RA, Paulosky KE, Szigety KM, Cao Y, Zhang X, Feng Z, He X, Ma J, Hua X. Menin-mediated repression of glycolysis in combination with autophagy protects colon cancer against small molecule EGFR inhibitors. Molecular Cancer Therapeutics. PMID 32879052 DOI: 10.1158/1535-7163.Mct-20-0101 |
0.395 |
|
| 2020 |
He X, Feng Z, Ma J, Ling S, Cao Y, Gurung B, Wu Y, Katona BW, O'Dwyer KP, Siegel DL, June CH, Hua X. Bi-specific and Split CAR T Cells Targeting CD13 and TIM3 Eradicate Acute Myeloid Leukemia. Blood. PMID 31951650 DOI: 10.1182/Blood.2019002779 |
0.315 |
|
| 2019 |
Ma J, He X, Cao Y, O'dwyer K, Szigety KM, Wu Y, Gurung B, Feng Z, Kanota BW, Hua X. Islet-Specific Prmt5 Excision Leads to Reduced Insulin Expression and Glucose Intolerance in Mice. The Journal of Endocrinology. PMID 31539871 DOI: 10.1530/Joe-19-0268 |
0.403 |
|
| 2019 |
Wu Y, Doepner M, Hojnacki T, Feng Z, Katona BW, He X, Ma J, Cao Y, Busino L, Zhou F, Hua X. Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway. American Journal of Cancer Research. 9: 1682-1694. PMID 31497350 |
0.409 |
|
| 2019 |
Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J. Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish. Stem Cells (Dayton, Ohio). PMID 31116894 DOI: 10.1002/Stem.3040 |
0.388 |
|
| 2019 |
Katona BW, Glynn RA, Paulosky KE, Feng Z, Davis CI, Ma J, Berry CT, Szigety KM, Matkar S, Liu Y, Wang H, Wu Y, He X, Freedman BD, Brady DC, ... Hua X, et al. Combined menin and EGFR inhibitors synergize to suppress colorectal cancer via EGFR-independent and calcium-mediated repression of SKP2 transcription. Cancer Research. PMID 30877106 DOI: 10.1158/0008-5472.Can-18-2133 |
0.382 |
|
| 2019 |
Xing B, Ma J, Jiang Z, Feng Z, Ling S, Szigety K, Su W, Zhang L, Jia R, Sun Y, Zhang L, Kong X, Ma X, Hua X. GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in β cells. The Journal of Cell Biology. PMID 30792230 DOI: 10.1083/Jcb.201805049 |
0.483 |
|
| 2019 |
Jiang Z, Xing B, Feng Z, Ma J, Ma X, Hua X. Menin Upregulates FOXO1 Protein Stability by Repressing Skp2-Mediated Degradation in β Cells. Pancreas. PMID 30629029 DOI: 10.1097/Mpa.0000000000001239 |
0.466 |
|
| 2018 |
Jiang Z, Shi D, Tu Y, Tian J, Zhang W, Xing B, Wang J, Liu S, Lou J, Gustafsson JÅ, Hua X, Ma X. Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes via FOXO1/Menin-Mediated Epigenetic Regulation. Diabetes. PMID 29716892 DOI: 10.2337/Db17-0885 |
0.422 |
|
| 2018 |
Ma J, Matkar S, He X, Hua X. FOXO Family in regulating Cancer and Metabolism. Seminars in Cancer Biology. PMID 29410116 DOI: 10.1016/J.Semcancer.2018.01.018 |
0.37 |
|
| 2017 |
Li JWY, Hua X, Reidy-Lagunes D, Untch BR. MENIN loss as a tissue-specific driver of tumorigenesis. Molecular and Cellular Endocrinology. PMID 28965973 DOI: 10.1016/J.Mce.2017.09.032 |
0.431 |
|
| 2017 |
Feng Z, Ma J, Hua X. Epigenetic regulation by the menin pathway. Endocrine-Related Cancer. PMID 28811300 DOI: 10.1530/ERC-17-0298 |
0.437 |
|
| 2017 |
Wang L, Matkar S, Xie G, An C, He X, Kong X, Liu X, Hua X. BRD4 Inhibitor IBET Upregulates p27kip/cip Protein Stability in Neuroendocrine Tumor Cells. Cancer Biology & Therapy. 0. PMID 28281917 DOI: 10.1080/15384047.2017.1294291 |
0.458 |
|
| 2017 |
Muhammad AB, Xing B, Liu C, Naji A, Ma X, Simmons RA, Hua X. Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00241.2016. PMID 28270438 DOI: 10.1152/Ajpendo.00241.2016 |
0.475 |
|
| 2016 |
Feng Z, Wang L, Sun Y, Jiang Z, Domsic J, An C, Xing B, Tian J, Liu X, Metz DC, Yang X, Marmorstein R, Ma X, Hua X. Menin and Daxx Interact to Control Neuroendocrine Tumors via Epigenetic Regulation of Membrane Metallo-Endopeptidase. Cancer Research. PMID 27872097 DOI: 10.1158/0008-5472.Can-16-1567 |
0.57 |
|
| 2015 |
He X, Wang L, Yan J, Yuan C, Witze ES, Hua X. Menin Localization In Cell Membrane Compartment. Cancer Biology & Therapy. 0. PMID 26560942 DOI: 10.1080/15384047.2015.1108497 |
0.374 |
|
| 2015 |
Matkar S, Sharma P, Gao S, Gurung B, Katona BW, Liao J, Muhammad AB, Kong XC, Wang L, Jin G, Dang CV, Hua X. An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis. Cancer Cell. 28: 472-85. PMID 26461093 DOI: 10.1016/J.Ccell.2015.09.005 |
0.396 |
|
| 2015 |
Zhu J, Sammons MA, Donahue G, Dou Z, Vedadi M, Getlik M, Barsyte-Lovejoy D, Al-awar R, Katona BW, Shilatifard A, Huang J, Hua X, Arrowsmith CH, Berger SL. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 525: 206-11. PMID 26331536 DOI: 10.1038/Nature15251 |
0.388 |
|
| 2015 |
Kong X, Zhang L, Hua X, Ma X. Squamosamide Derivative FLZ Protects Pancreatic β-Cells from Glucotoxicity by Stimulating Akt-FOXO1 Pathway. Journal of Diabetes Research. 2015: 803986. PMID 26167511 DOI: 10.1155/2015/803986 |
0.334 |
|
| 2015 |
Gurung B, Hua X, Runske M, Bennett B, LiVolsi V, Roses R, Fraker DA, Metz DC. PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target. Cancer Biology & Therapy. 16: 219-24. PMID 25482929 DOI: 10.4161/15384047.2014.987574 |
0.392 |
|
| 2014 |
Gurung B, Katona BW, Hua X. Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells. Oncoscience. 1: 562-6. PMID 25594065 DOI: 10.18632/oncoscience.79 |
0.402 |
|
| 2014 |
Katona BW, Liu Y, Ma A, Jin J, Hua X. EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells. Cancer Biology & Therapy. 15: 1677-87. PMID 25535899 DOI: 10.4161/15384047.2014.972776 |
0.339 |
|
| 2014 |
Matkar S, Katona BW, Hua X. Harnessing the hidden antitumor power of the MLL-AF4 oncogene to fight leukemia. Cancer Cell. 25: 411-3. PMID 24735921 DOI: 10.1016/J.Ccr.2014.03.028 |
0.357 |
|
| 2014 |
Gurung B, Muhammad AB, Hua X. Menin is required for optimal processing of the microRNA let-7a. The Journal of Biological Chemistry. 289: 9902-8. PMID 24563463 DOI: 10.1074/Jbc.M113.520692 |
0.372 |
|
| 2014 |
Katona B, Sholomskas L, Hua X. Mo1648 Enhancing the Efficacy of EGFR Inhibitors in Colon Cancer Cells Through Targeted Disruption of Menin-MLL1 Gastroenterology. 146: S-626-S-627. DOI: 10.1016/S0016-5085(14)62265-4 |
0.311 |
|
| 2013 |
Sun D, Zhang Y, Wang C, Hua X, Zhang XA, Yan J. Sox9-related signaling controls zebrafish juvenile ovary–testis transformation Cell Death and Disease. 4. PMID 24263104 DOI: 10.1038/Cddis.2013.456 |
0.397 |
|
| 2013 |
Gurung B, Hua X. Menin/PRMT5/hedgehog signaling: a potential target for the treatment of multiple endocrine neoplasia type 1 tumors. Epigenomics. 5: 469-71. PMID 24059791 DOI: 10.2217/Epi.13.47 |
0.336 |
|
| 2013 |
Gurung B, Feng Z, Hua X. Menin directly represses Gli1 expression independent of canonical Hedgehog signaling. Molecular Cancer Research : McR. 11: 1215-22. PMID 23928057 DOI: 10.1158/1541-7786.Mcr-13-0170 |
0.589 |
|
| 2013 |
Matkar S, Thiel A, Hua X. Menin: a scaffold protein that controls gene expression and cell signaling. Trends in Biochemical Sciences. 38: 394-402. PMID 23850066 DOI: 10.1016/J.Tibs.2013.05.005 |
0.802 |
|
| 2013 |
Gurung B, Feng Z, Iwamoto DV, Thiel A, Jin G, Fan CM, Ng JM, Curran T, Hua X. Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome. Cancer Research. 73: 2650-8. PMID 23580576 DOI: 10.1158/0008-5472.Can-12-3158 |
0.807 |
|
| 2013 |
Thiel AT, Feng Z, Pant DK, Chodosh LA, Hua X. The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia. Haematologica. 98: 918-27. PMID 23349306 DOI: 10.3324/Haematol.2012.074195 |
0.802 |
|
| 2012 |
Wang X, He H, Tang W, Zhang XA, Hua X, Yan J. Two origins of blastemal progenitors define blastemal regeneration of zebrafish lower jaw. Plos One. 7: e45380. PMID 23028974 DOI: 10.1371/Journal.Pone.0045380 |
0.394 |
|
| 2012 |
Wu Y, Feng ZJ, Gao SB, Matkar S, Xu B, Duan HB, Lin X, Li SH, Hua X, Jin GH. Interplay between menin and K-Ras in regulating lung adenocarcinoma. The Journal of Biological Chemistry. 287: 40003-11. PMID 23027861 DOI: 10.1074/Jbc.M112.382416 |
0.373 |
|
| 2012 |
Thiel AT, Huang J, Lei M, Hua X. Menin as a hub controlling mixed lineage leukemia Bioessays. 34: 771-780. PMID 22829075 DOI: 10.1002/Bies.201200007 |
0.783 |
|
| 2012 |
Huang J, Gurung B, Wan B, Matkar S, Veniaminova NA, Wan K, Merchant JL, Hua X, Lei M. The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature. 482: 542-6. PMID 22327296 DOI: 10.1038/Nature10806 |
0.508 |
|
| 2012 |
Thiel AT, Hua X. Abstract 4093: Investigating a role for menin and MLL-AF9 in suppressing C/EBPβ-mediated mixed lineage leukemia cell differentiation Cancer Research. 72: 4093-4093. DOI: 10.1158/1538-7445.Am2012-4093 |
0.794 |
|
| 2011 |
Zhang H, Liu ZG, Hua XX. Menin expression is regulated by transforming growth factor beta signaling in leukemia cells. Chinese Medical Journal. 124: 1556-62. PMID 21740816 |
0.344 |
|
| 2011 |
Xu B, Zeng DQ, Wu Y, Zheng R, Gu L, Lin X, Hua X, Jin GH. Tumor suppressor menin represses paired box gene 2 expression via Wilms tumor suppressor protein-polycomb group complex. The Journal of Biological Chemistry. 286: 13937-44. PMID 21378168 DOI: 10.1074/Jbc.M110.197830 |
0.545 |
|
| 2011 |
Gao SB, Feng ZJ, Xu B, Chen Y, Zheng HH, Yin P, Hua X, Jin GH. Menin represses malignant phenotypes of melanoma through regulating multiple pathways. Journal of Cellular and Molecular Medicine. 15: 2353-63. PMID 21129151 DOI: 10.1111/J.1582-4934.2010.01222.X |
0.499 |
|
| 2011 |
He H, Hua X, Yan J. Epigenetic regulations in hematopoietic Hox code. Oncogene. 30: 379-388. PMID 20972460 DOI: 10.1038/Onc.2010.484 |
0.466 |
|
| 2010 |
Yang Y, Wang H, Hua X. Deletion of the Men1 gene prevents streptozotocin-induced hyperglycemia in mice. Experimental Diabetes Research. 2010: 876701. PMID 21318185 DOI: 10.1155/2010/876701 |
0.403 |
|
| 2010 |
Yang Y, Gurung B, Wu T, Wang H, Stoffers DA, Hua X. Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene. Proceedings of the National Academy of Sciences of the United States of America. 107: 20358-63. PMID 21059956 DOI: 10.1073/Pnas.1012257107 |
0.356 |
|
| 2010 |
Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell. 18: 329-40. PMID 20951943 DOI: 10.1016/J.Ccr.2010.08.012 |
0.394 |
|
| 2010 |
Wu T, Zhang X, Huang X, Yang Y, Hua X. Regulation of cyclin B2 expression and cell cycle G2/m transition by menin. The Journal of Biological Chemistry. 285: 18291-300. PMID 20404349 DOI: 10.1074/Jbc.M110.106575 |
0.449 |
|
| 2010 |
Thiel AT, Blessington P, Zou T, Feather D, Wu X, Yan J, Zhang H, Liu Z, Ernst P, Koretzky GA, Hua X. MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele. Cancer Cell. 17: 148-59. PMID 20159607 DOI: 10.1016/J.Ccr.2009.12.034 |
0.778 |
|
| 2009 |
Maillard I, Chen YX, Friedman A, Yang Y, Tubbs AT, Shestova O, Pear WS, Hua X. Menin regulates the function of hematopoietic stem cells and lymphoid progenitors. Blood. 113: 1661-9. PMID 19228930 DOI: 10.1182/Blood-2008-01-135012 |
0.476 |
|
| 2009 |
Yan J, Yang Y, Zhang H, King C, Kan HM, Cai Y, Yuan CX, Bloom GS, Hua X. Menin interacts with IQGAP1 to enhance intercellular adhesion of beta-cells. Oncogene. 28: 973-82. PMID 19079338 DOI: 10.1038/Onc.2008.435 |
0.45 |
|
| 2008 |
Wu X, Hua X. Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective. Current Molecular Medicine. 8: 805-15. PMID 19075677 DOI: 10.2174/156652408786733702 |
0.461 |
|
| 2008 |
Gao SB, Hua X, Jin GH. Menin regulates endocrine diseases by controlling histone modification and gene transcription Annales D Endocrinologie. 69: 426-432. PMID 18752793 DOI: 10.1016/J.Ando.2008.06.001 |
0.386 |
|
| 2007 |
La P, Yang Y, Karnik SK, Silva AC, Schnepp RW, Kim SK, Hua X. Menin-mediated caspase 8 expression in suppressing multiple endocrine neoplasia type 1. The Journal of Biological Chemistry. 282: 31332-40. PMID 17766243 DOI: 10.1074/Jbc.M609555200 |
0.742 |
|
| 2007 |
Yang Y, Hua X. In search of tumor suppressing functions of menin. Molecular and Cellular Endocrinology. 265: 34-41. PMID 17222504 DOI: 10.1016/J.Mce.2006.12.032 |
0.505 |
|
| 2007 |
Maillard I, Chen Y, Tubbs AT, Shestova O, Pear WS, Hua X. Menin Regulates the Function of Lymphoid Progenitors and Hematopoietic Stem Cells. Blood. 110: 1257-1257. DOI: 10.1182/Blood.V110.11.1257.1257 |
0.493 |
|
| 2006 |
Yan J, Chen YX, Desmond A, Silva A, Yang Y, Wang H, Hua X. Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cells. Plos One. 1: e47. PMID 17183676 DOI: 10.1371/Journal.Pone.0000047 |
0.459 |
|
| 2006 |
Andl CD, Fargnoli BB, Okawa T, Bowser M, Takaoka M, Nakagawa H, Klein-Szanto A, Hua X, Herlyn M, Rustgi AK. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. Cancer Research. 66: 9878-85. PMID 17047049 DOI: 10.1158/0008-5472.Can-05-4157 |
0.353 |
|
| 2006 |
Schnepp RW, Chen YX, Wang H, Cash T, Silva A, Diehl JA, Brown E, Hua X. Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells. Cancer Research. 66: 5707-15. PMID 16740708 DOI: 10.1158/0008-5472.Can-05-4518 |
0.747 |
|
| 2006 |
La P, Desmond A, Hou Z, Silva AC, Schnepp RW, Hua X. Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression. Oncogene. 25: 3537-46. PMID 16449969 DOI: 10.1038/Sj.Onc.1209400 |
0.791 |
|
| 2006 |
Chen YX, Yan J, Keeshan K, Tubbs AT, Wang H, Silva A, Brown EJ, Hess JL, Pear WS, Hua X. The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression. Proceedings of the National Academy of Sciences of the United States of America. 103: 1018-23. PMID 16415155 DOI: 10.1073/Pnas.0510347103 |
0.556 |
|
| 2005 |
Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 102: 749-54. PMID 15640349 DOI: 10.1073/Pnas.0408836102 |
0.775 |
|
| 2005 |
Hess JL, Yang Z, Wang H, Chen Y, Milne TA, Martin ME, Slany RK, Hua X. Interaction of MLL Amino Terminal Sequences with Menin Is Required for Transformation. Blood. 106: 664-664. DOI: 10.1182/Blood.V106.11.664.664 |
0.509 |
|
| 2004 |
Schnepp RW, Hou Z, Wang H, Petersen C, Silva A, Masai H, Hua X. Functional interaction between tumor suppressor menin and activator of S-phase kinase. Cancer Research. 64: 6791-6. PMID 15374998 DOI: 10.1158/0008-5472.Can-04-0724 |
0.756 |
|
| 2004 |
La P, Silva AC, Hou Z, Wang H, Schnepp RW, Yan N, Shi Y, Hua X. Direct binding of DNA by tumor suppressor menin. The Journal of Biological Chemistry. 279: 49045-54. PMID 15331604 DOI: 10.1074/Jbc.M409358200 |
0.72 |
|
| 2004 |
La P, Schnepp RW, D Petersen C, C Silva A, Hua X. Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2. Endocrinology. 145: 3443-50. PMID 15044367 DOI: 10.1210/En.2004-0124 |
0.798 |
|
| 2004 |
Schnepp RW, Mao H, Sykes SM, Zong WX, Silva A, La P, Hua X. Menin induces apoptosis in murine embryonic fibroblasts. The Journal of Biological Chemistry. 279: 10685-91. PMID 14688275 DOI: 10.1074/Jbc.M308073200 |
0.736 |
|
| 2003 |
Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X. Menin associates with FANCD2, a protein involved in repair of DNA damage. Cancer Research. 63: 4204-10. PMID 12874027 |
0.718 |
|
| 2003 |
Schnepp R, Hua X. A tumor-suppressing duo: TGFbeta and activin modulate a similar transcriptome. Cancer Biology & Therapy. 2: 171-2. PMID 12750557 DOI: 10.4161/Cbt.2.2.334 |
0.705 |
|
| 2003 |
La P, Morgan TA, Sykes SM, Mao H, Schnepp RW, Petersen CD, Hua X. Fusion proteins of retinoid receptors antagonize TGF-beta-induced growth inhibition of lung epithelial cells. Oncogene. 22: 198-210. PMID 12527889 DOI: 10.1038/Sj.Onc.1206100 |
0.702 |
|
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