Richard Pestell - Publications

Affiliations: 
Biochemistry and Molecular Biology Thomas Jefferson University 
Area:
Molecular Biology, Biochemistry, Cell Biology, Oncology

440 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen K, Jiao X, Ashton A, Di Rocco A, Pestell TG, Sun Y, Zhao J, Casimiro MC, Li Z, Lisanti MP, McCue PA, Shen D, Achilefu S, Rui H, Pestell RG. The membrane-associated form of cyclin D1 enhances cellular invasion. Oncogenesis. 9: 83. PMID 32948740 DOI: 10.1038/s41389-020-00266-y  0.8
2020 Chen K, Jiao X, Di Rocco A, Shen D, Xu S, Ertel A, Yu Z, Di Sante G, Wang M, Li Z, Pestell TG, Casimiro MC, Skordalakes E, Achilefu S, Pestell RG. Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation. Cell Reports. 32: 108151. PMID 32937140 DOI: 10.1016/j.celrep.2020.108151  0.76
2020 Upadhyaya C, Jiao X, Ashton A, Patel K, Kossenkov AV, Pestell RG. The G protein coupled receptor CCR5 in cancer. Advances in Cancer Research. 145: 29-47. PMID 32089164 DOI: 10.1016/bs.acr.2019.11.001  0.32
2019 Jiao X, Nawab O, Patel T, Kossenkov AV, Halama N, Jaeger D, Pestell RG. Recent Advances targeting CCR5 for Cancer and its Role in Immuno-Oncology. Cancer Research. PMID 31292161 DOI: 10.1158/0008-5472.CAN-19-1167  0.32
2019 Jiao X, Nawab O, Patel T, Kossenkov AV, Halama N, Jaeger D, Pestell RG. Recent Advances targeting CCR5 for Cancer and its Role in Immuno-Oncology. Cancer Research. PMID 31292161 DOI: 10.1158/0008-5472.CAN-19-1167  0.32
2019 Di Sante G, Pagé J, Jiao X, Nawab O, Cristofanilli M, Skordalakes E, Pestell RG. Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology. Expert Review of Anticancer Therapy. 1-19. PMID 31219365 DOI: 10.1080/14737140.2019.1615889  0.32
2019 Li Z, Jiao X, Di Sante G, Ertel A, Casimiro MC, Wang M, Katiyar S, Ju X, Klopfenstein DV, Tozeren A, Dampier W, Chepelev I, Jeltsch A, Pestell RG. Cyclin D1 integrates G9a-mediated histone methylation. Oncogene. PMID 30718920 DOI: 10.1038/s41388-019-0723-8  0.76
2018 Jiao X, Li Z, Wang M, Katiyar S, Di Sante G, Farshchian M, South AP, Cocola C, Colombo D, Reinbold R, Zucchi I, Wu K, Tabas I, Spike BT, Pestell RG. Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool. Stem Cell Reports. PMID 30554919 DOI: 10.1016/j.stemcr.2018.11.010  0.4
2018 Zheng Z, Nayak L, Wang W, Yurdagul A, Wang X, Cai B, Lapping S, Ozcan L, Ramakrishnan R, Pestell RG, Jain MK, Tabas I. An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. Blood. PMID 30504459 DOI: 10.1182/blood-2018-07-864843  0.32
2018 Xu H, Bai X, Yu S, Liu Q, Pestell RG, Wu K. MAT1 correlates with molecular subtypes and predicts poor survival in breast cancer. Chinese Journal of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu. 30: 351-363. PMID 30046229 DOI: 10.21147/j.issn.1000-9604.2018.03.07  0.36
2018 Wang G, Gormley M, Qiao J, Zhao Q, Wang M, Di Sante G, Deng S, Dong L, Pestell T, Ju X, Casimiro MC, Addya S, Ertel A, Tozeren A, Li Q, ... ... Pestell RG, et al. Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome. Theranostics. 8: 2251-2263. PMID 29721077 DOI: 10.7150/thno.23877  0.76
2018 Liu Q, Li A, Yu S, Qin S, Han N, Pestell RG, Han X, Wu K. DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis. Journal of Hematology & Oncology. 11: 53. PMID 29636079 DOI: 10.1186/s13045-018-0597-1  0.36
2018 Hernández-Esquivel MA, Pérez-Torres A, Romero-Romero L, Reyes-Matute A, Loaiza B, Mellado-Sánchez G, Pavón L, Medina-Rivero E, Pestell RG, Pérez-Tapia SM, Velasco-Velázquez MA. The dialyzable leukocyte extract Transferon inhibits tumor growth and brain metastasis in a murine model of prostate cancer. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 101: 938-944. PMID 29635903 DOI: 10.1016/j.biopha.2018.03.012  0.44
2018 Jiao X, Velasco-Velázquez MA, Wang M, Li Z, Rui H, Peck AR, Korkola JE, Chen X, Xu S, DuHadaway JB, Guerrero-Rodriguez S, Addya S, Sicoli D, Mu Z, Zhang G, ... ... Pestell RG, et al. CCR5 governs DNA damage and breast cancer stem cell expansion. Cancer Research. PMID 29358169 DOI: 10.1158/0008-5472.CAN-17-0915  0.56
2017 Di Sante G, Di Rocco A, Pupo C, Casimiro MC, Pestell RG. Hormone-induced DNA damage response and repair mediated by cyclin D1 in breast and prostate cancer. Oncotarget. 8: 81803-81812. PMID 29137223 DOI: 10.18632/oncotarget.19413  0.76
2017 Pestell TG, Jiao X, Kumar M, Peck AR, Prisco M, Deng S, Li Z, Ertel A, Casimiro MC, Ju X, Di Rocco A, Di Sante G, Katiyar S, Shupp A, Lisanti MP, ... ... Pestell RG, et al. Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth. Oncotarget. 8: 81754-81775. PMID 29137220 DOI: 10.18632/oncotarget.19953  0.8
2017 Yu S, Li A, Liu Q, Yuan X, Xu H, Jiao D, Pestell RG, Han X, Wu K. Recent advances of bispecific antibodies in solid tumors. Journal of Hematology & Oncology. 10: 155. PMID 28931402 DOI: 10.1186/s13045-017-0522-z  0.36
2017 Di Sante G, Di Rocco A, Pupo C, Casimiro MC, Pestell RG. Hormone-induced DNA damage response and repair mediated by cyclin D1 in breast and prostate cancer. Oncotarget. PMID 28754843 DOI: 10.18632/oncotarget.19413  0.76
2017 Xu H, Yu S, Yuan X, Xiong J, Kuang D, Pestell RG, Wu K. DACH1 suppresses breast cancer as a negative regulator of CD44. Scientific Reports. 7: 4361. PMID 28659634 DOI: 10.1038/s41598-017-04709-2  0.36
2017 Casimiro MC, Di Sante G, Di Rocco A, Loro E, Pupo C, Pestell T, Bisetto S, Velasco-Velàzquez MA, Jiao X, Li Z, Kusminski CM, Seifert EL, Wang C, Ly D, Zheng B, ... ... Pestell RG, et al. Cyclin D1 restrains oncogene-induced autophagy by regulating the AMPK-LKB1 signaling axis. Cancer Research. PMID 28522753 DOI: 10.1158/0008-5472.CAN-16-0425  0.76
2017 Xu H, Yu S, Liu Q, Yuan X, Mani S, Pestell RG, Wu K. Recent advances of highly selective CDK4/6 inhibitors in breast cancer. Journal of Hematology & Oncology. 10: 97. PMID 28438180 DOI: 10.1186/s13045-017-0467-2  0.44
2017 Martinez-Outschoorn UE, Peiris-Pagés M, Pestell RG, Sotgia F, Lisanti MP. Cancer metabolism: a therapeutic perspective. Nature Reviews. Clinical Oncology. PMID 28094266 DOI: 10.1038/nrclinonc.2017.1  0.8
2017 Shupp A, Casimiro MC, Pestell RG. Biological functions of CDK5 and potential CDK5 targeted clinical treatments. Oncotarget. PMID 28077789 DOI: 10.18632/oncotarget.14538  0.76
2016 Marampon F, Gravina GL, Ju X, Vetuschi A, Sferra R, Casimiro MC, Pompili S, Festuccia C, Colapietro A, Gaudio E, Di Cesare E, Tombolini V, Pestell RG. Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage. Oncotarget. 7: 64526. PMID 28042139 DOI: 10.18632/oncotarget.12267  0.76
2016 Ju X, Jiao X, Ertel A, Casimiro MC, Di Sante G, Deng S, Li Z, Di Rocco A, Zhan T, Hawkins A, Stoyanova T, Ando S, Fatatis A, Lisanti MP, Gomella LG, ... ... Pestell RG, et al. SRC ONCOGENE INDUCES TROP2 PROTEOLYTIC ACTIVATION VIA CYCLIN D1. Cancer Research. PMID 27634768 DOI: 10.1158/0008-5472.CAN-15-3327  0.8
2016 Peiris-Pagès M, Martinez-Outschoorn UE, Pestell RG, Sotgia F, Lisanti MP. Cancer stem cell metabolism. Breast Cancer Research : Bcr. 18: 55. PMID 27220421 DOI: 10.1186/s13058-016-0712-6  0.72
2016 Kong D, Liu Y, Liu Q, Han N, Zhang C, Pestell RG, Wu K, Wu G. The retinal determination gene network: from developmental regulator to cancer therapeutic target. Oncotarget. PMID 27203207 DOI: 10.18632/oncotarget.9394  0.36
2016 Di Sante G, Casimiro MC, Pestell TG, Pestell RG. Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy. Journal of Visualized Experiments : Jove. PMID 27168174 DOI: 10.3791/53657  0.8
2016 Martinez-Outschoorn UE, Peiris-Pagés M, Pestell RG, Sotgia F, Lisanti MP. Cancer metabolism: a therapeutic perspective. Nature Reviews. Clinical Oncology. PMID 27141887 DOI: 10.1038/nrclinonc.2016.60  0.72
2016 Zhao Q, Deng S, Wang G, Liu C, Meng L, Qiao S, Shen L, Zhang Y, Lü J, Li W, Zhang Y, Wang M, Pestell RG, Liang C, Yu Z. A direct quantification method for measuring plasma MicroRNAs identified potential biomarkers for detecting metastatic breast cancer. Oncotarget. PMID 26967564 DOI: 10.18632/oncotarget.7990  0.72
2016 Jiao X, Rizvanov AA, Cristofanilli M, Miftakhova RR, Pestell RG. Breast Cancer Stem Cell Isolation. Methods in Molecular Biology (Clifton, N.J.). 1406: 121-35. PMID 26820950 DOI: 10.1007/978-1-4939-3444-7_10  0.32
2016 Marampon F, Gravina GL, Ju X, Vetuschi A, Sferra R, Casimiro MC, Pompili S, Festuccia C, Colapietro A, Gaudio E, Di Cesare E, Tombolini V, Pestell RG. Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage. Oncotarget. 7: 5383-400. PMID 26689991 DOI: 10.18632/oncotarget.6579  0.76
2016 Marampon F, Gravina GL, Ju X, Vetuschi A, Sferra R, Casimiro MC, Pompili S, Festuccia C, Colapietro A, Gaudio E, Di Cesare E, Tombolini V, Pestell RG. Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage Oncotarget. 7: 5383-5400. DOI: 10.18632/oncotarget.6579  0.72
2015 Xu H, Tian Y, Yuan X, Wu H, Liu Q, Pestell RG, Wu K. The role of CD44 in epithelial-mesenchymal transition and cancer development. Oncotargets and Therapy. 8: 3783-92. PMID 26719706 DOI: 10.2147/OTT.S95470  0.72
2015 Wu K, Yuan X, Pestell R. Endogenous Dach1 in cancer. Oncoscience. 2: 803-4. PMID 26682253 DOI: 10.18632/oncoscience.251  0.72
2015 Casimiro MC, Di Sante G, Ju X, Li Z, Chen K, Crosariol M, Yaman I, Gormley M, Meng H, Lisanti MP, Pestell RG. Cyclin D1 promotes androgen-dependent DNA damage repair in prostate cancer cells. Cancer Research. PMID 26582866 DOI: 10.1158/0008-5472.CAN-15-0999  0.8
2015 Pestell RG, Fatatis A, Jiao X. Mitochondrial mass and DNA repair in breast cancer stem cells. Oncotarget. PMID 26564961 DOI: 10.18632/oncotarget.6305  0.8
2015 Raman P, Purwin T, Pestell R, Tozeren A. FXYD5 is a Marker for Poor Prognosis and a Potential Driver for Metastasis in Ovarian Carcinomas. Cancer Informatics. 14: 113-9. PMID 26494976 DOI: 10.4137/CIN.S30565  0.72
2015 Zhang J, Wang C, Chen X, Takada M, Fan C, Zheng X, Wen H, Liu Y, Wang C, Pestell RG, Aird KM, Kaelin WG, Liu XS, Zhang Q. EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer. The Embo Journal. PMID 26492917 DOI: 10.15252/embj.201591437  0.72
2015 Lamb R, Ozsvari B, Bonuccelli G, Smith DL, Pestell RG, Martinez-Outschoorn UE, Clarke RB, Sotgia F, Lisanti MP. Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells. Oncotarget. 6: 21892-905. PMID 26323205  0.72
2015 Casimiro MC, Arnold A, Pestell RG. Kinase independent oncogenic cyclin D1. Aging. 7: 455-6. PMID 26187783  0.8
2015 Trerotola M, Ganguly KK, Fazli L, Fedele C, Lu H, Dutta A, Liu Q, De Angelis T, Riddell LW, Riobo NA, Gleave ME, Zoubeidi A, Pestell RG, Altieri DC, Languino LR. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts. Oncotarget. 6: 14318-28. PMID 26015409  0.8
2015 Casimiro MC, Di Sante G, Crosariol M, Loro E, Dampier W, Ertel A, Yu Z, Saria EA, Papanikolaou A, Li Z, Wang C, Addya S, Lisanti MP, Fortina P, Cardiff RD, ... ... Pestell RG, et al. Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis. Oncotarget. 6: 8525-38. PMID 25940700  0.8
2015 Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, Di Sante G, Xu S, Wang Q, Li K, Sun X, Xu C, Li Z, Casimiro MC, Ertel A, ... ... Pestell RG, et al. The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module. Cancer Research. 75: 1992-2004. PMID 25769723 DOI: 10.1158/0008-5472.CAN-14-0611  0.8
2015 Pestell RG, Rizvanov AA. Antibiotics for cancer therapy. Oncotarget. 6: 2587-8. PMID 25739117 DOI: 10.18632/oncotarget.3388  0.8
2015 Lamb R, Harrison H, Smith DL, Townsend PA, Jackson T, Ozsvari B, Martinez-Outschoorn UE, Pestell RG, Howell A, Lisanti MP, Sotgia F. Targeting tumor-initiating cells: eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction. Oncotarget. 6: 4585-601. PMID 25671304  0.8
2015 Di Sante G, Wang L, Wang C, Jiao X, Casimiro MC, Chen K, Pestell TG, Yaman I, Di Rocco A, Sun X, Horio Y, Powell MJ, He X, McBurney MW, Pestell RG. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration. Molecular Endocrinology (Baltimore, Md.). 29: 200-12. PMID 25545407 DOI: 10.1210/me.2014-1228  0.8
2015 Di Sante G, Pestell TG, Casimiro MC, Bisetto S, Powell MJ, Lisanti MP, Cordon-Cardo C, Castillo-Martin M, Bonal DM, Debattisti V, Chen K, Wang L, He X, McBurney MW, Pestell RG. Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria. The American Journal of Pathology. 185: 266-79. PMID 25529796 DOI: 10.1016/j.ajpath.2014.09.014  0.8
2015 Cekanova M, Fernando RI, Siriwardhana N, Sukhthankar M, De la Parra C, Woraratphoka J, Malone C, Ström A, Baek SJ, Wade PA, Saxton AM, Donnell RM, Pestell RG, Dharmawardhane S, Wimalasena J. BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion. Experimental Cell Research. 331: 1-10. PMID 25499972 DOI: 10.1016/j.yexcr.2014.11.016  0.8
2015 Wang C, Zhang X, Tian L, Pestell RG. Emerging roles of peroxisome proliferator-activated receptor gamma in cancer Molecular Oncology: Causes of Cancer and Targets For Treatment. 392-402. DOI: 10.1017/CBO9781139046947.034  0.72
2014 Sicoli D, Jiao X, Ju X, Velasco-Velazquez M, Ertel A, Addya S, Li Z, Andò S, Fatatis A, Paudyal B, Cristofanilli M, Thakur ML, Lisanti MP, Pestell RG. CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines. Cancer Research. 74: 7103-14. PMID 25452256 DOI: 10.1158/0008-5472.CAN-14-0612  0.8
2014 Pavlides S, Gutierrez-Pajares JL, Katiyar S, Jasmin JF, Mercier I, Walters R, Pavlides C, Pestell RG, Lisanti MP, Frank PG. Caveolin-1 regulates the anti-atherogenic properties of macrophages. Cell and Tissue Research. 358: 821-31. PMID 25322709 DOI: 10.1007/s00441-014-2008-4  0.8
2014 Ringer L, Sirajuddin P, Tricoli L, Waye S, Choudhry MU, Parasido E, Sivakumar A, Heckler M, Naeem A, Abdelgawad I, Liu X, Feldman AS, Lee RJ, Wu CL, Yenugonda V, ... ... Pestell RG, et al. The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells. Oncotarget. 5: 10678-91. PMID 25296977 DOI: 10.18632/oncotarget.2528  0.8
2014 Velasco-Velázquez M, Xolalpa W, Pestell RG. The potential to target CCL5/CCR5 in breast cancer. Expert Opinion On Therapeutic Targets. 18: 1265-75. PMID 25256399 DOI: 10.1517/14728222.2014.949238  0.8
2014 Tian L, Wang C, Hagen FK, Gormley M, Addya S, Soccio R, Casimiro MC, Zhou J, Powell MJ, Xu P, Deng H, Sauve AA, Pestell RG. Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells. Oncotarget. 5: 7303-15. PMID 25229978  0.76
2014 Jin L, Lim M, Zhao S, Sano Y, Simone BA, Savage JE, Wickstrom E, Camphausen K, Pestell RG, Simone NL. The metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 cluster. Breast Cancer Research and Treatment. 146: 41-50. PMID 24863696 DOI: 10.1007/s10549-014-2978-7  0.8
2014 Li Z, Chen K, Jiao X, Wang C, Willmarth NE, Casimiro MC, Li W, Ju X, Kim SH, Lisanti MP, Katzenellenbogen JA, Pestell RG. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling. Cancer Research. 74: 3959-70. PMID 24830723 DOI: 10.1158/0008-5472.CAN-13-3137  0.8
2014 Yu Z, Xu Z, Disante G, Wright J, Wang M, Li Y, Zhao Q, Ren T, Ju X, Gutman E, Wang G, Addya S, Li T, Xiang Z, Wang C, ... ... Pestell R, et al. miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget. 5: 1083-90. PMID 24658544  0.68
2014 Mercier I, Gonzales DM, Quann K, Pestell TG, Molchansky A, Sotgia F, Hulit J, Gandara R, Wang C, Pestell RG, Lisanti MP, Jasmin JF. CAPER, a novel regulator of human breast cancer progression. Cell Cycle (Georgetown, Tex.). 13: 1256-64. PMID 24621503 DOI: 10.4161/cc.28156  0.8
2014 Pestell RG, Yu Z. Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo. Asian Journal of Andrology. 16: 268-9. PMID 24435053 DOI: 10.4103/1008-682X.122364  0.8
2014 Casimiro MC, Velasco-Velázquez M, Aguirre-Alvarado C, Pestell RG. Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present. Expert Opinion On Investigational Drugs. 23: 295-304. PMID 24387133 DOI: 10.1517/13543784.2014.867017  0.8
2014 Wu K, Chen K, Wang C, Jiao X, Wang L, Zhou J, Wang J, Li Z, Addya S, Sorensen PH, Lisanti MP, Quong A, Ertel A, Pestell RG. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Research. 74: 829-39. PMID 24335958 DOI: 10.1158/0008-5472.CAN-13-2466  0.8
2014 Ju X, Casimiro MC, Gormley M, Meng H, Jiao X, Katiyar S, Crosariol M, Chen K, Wang M, Quong AA, Lisanti MP, Ertel A, Pestell RG. Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint. Cancer Research. 74: 508-19. PMID 24282282 DOI: 10.1158/0008-5472.CAN-13-1313  0.8
2014 Sun X, Jiao X, Pestell TG, Fan C, Qin S, Mirabelli E, Ren H, Pestell RG. MicroRNAs and cancer stem cells: the sword and the shield. Oncogene. 33: 4967-77. PMID 24240682 DOI: 10.1038/onc.2013.492  0.32
2014 Mercier I, Gonzales DM, Quann K, Pestell TG, Molchansky A, Sotgia F, Hulit J, Gandara R, Wang C, Pestell RG, Lisanti MP, Jasmin JF. CAPER, a novel regulator of human breast cancer progression Cell Cycle. 13: 1256-1264. DOI: 10.4161/cc.28156  0.8
2014 Pavlides S, Gutierrez-Pajares JL, Katiyar S, Jasmin JF, Mercier I, Walters R, Pavlides C, Pestell RG, Lisanti MP, Frank PG. Caveolin-1 regulates the anti-atherogenic properties of macrophages Cell and Tissue Research. 358: 821-831. DOI: 10.1007/s00441-014-2008-4  0.8
2014 Merchand-Reyes G, Pelayo R, Pavón L, Pestell RG, Velasco-Velázquez M. Role of Cancer Stem Cells in Metastasis Cancer Stem Cells. 259-271. DOI: 10.1002/9781118356203.ch20  0.8
2013 Yu Z, Wang L, Wang C, Ju X, Wang M, Chen K, Loro E, Li Z, Zhang Y, Wu K, Casimiro MC, Gormley M, Ertel A, Fortina P, Chen Y, ... ... Pestell RG, et al. Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. Nature Communications. 4: 2812. PMID 24287487 DOI: 10.1038/ncomms3812  0.76
2013 Lisanti MP, Sotgia F, Pestell RG, Howell A, Martinez-Outschoorn UE. Stromal glycolysis and MCT4 are hallmarks of DCIS progression to invasive breast cancer. Cell Cycle (Georgetown, Tex.). 12: 2935-6. PMID 23989616 DOI: 10.4161/cc.26280  0.8
2013 Martinez-Outschoorn UE, Whitaker-Menezes D, Valsecchi M, Martinez-Cantarin MP, Dulau-Florea A, Gong J, Howell A, Flomenberg N, Pestell RG, Wagner J, Arana-Yi C, Sharma M, Sotgia F, Lisanti MP. Reverse Warburg effect in a patient with aggressive B-cell lymphoma: is lactic acidosis a paraneoplastic syndrome? Seminars in Oncology. 40: 403-18. PMID 23972703 DOI: 10.1053/j.seminoncol.2013.04.016  0.8
2013 Casimiro MC, Wang C, Li Z, Di Sante G, Willmart NE, Addya S, Chen L, Liu Y, Lisanti MP, Pestell RG. Cyclin D1 determines estrogen signaling in the mammary gland in vivo. Molecular Endocrinology (Baltimore, Md.). 27: 1415-28. PMID 23864650 DOI: 10.1210/me.2013-1065  0.8
2013 Martinez-Outschoorn UE, Curry JM, Ko YH, Lin Z, Tuluc M, Cognetti D, Birbe RC, Pribitkin E, Bombonati A, Pestell RG, Howell A, Sotgia F, Lisanti MP. Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4. Cell Cycle (Georgetown, Tex.). 12: 2580-97. PMID 23860378 DOI: 10.4161/cc.25510  0.8
2013 Chen K, Wu K, Gormley M, Ertel A, Wang J, Zhang W, Zhou J, Disante G, Li Z, Rui H, Quong AA, McMahon SB, Deng H, Lisanti MP, Wang C, ... Pestell RG, et al. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. Oncotarget. 4: 923-35. PMID 23798621  0.8
2013 Pestell RG. New roles of cyclin D1. The American Journal of Pathology. 183: 3-9. PMID 23790801 DOI: 10.1016/j.ajpath.2013.03.001  0.8
2013 Velasco-Velázquez M, Pestell RG. The CCL5/CCR5 axis promotes metastasis in basal breast cancer. Oncoimmunology. 2: e23660. PMID 23734321 DOI: 10.4161/onci.23660  0.8
2013 Saleh AD, Simone BA, Palazzo J, Savage JE, Sano Y, Dan T, Jin L, Champ CE, Zhao S, Lim M, Sotgia F, Camphausen K, Pestell RG, Mitchell JB, Lisanti MP, et al. Caloric restriction augments radiation efficacy in breast cancer. Cell Cycle (Georgetown, Tex.). 12: 1955-63. PMID 23708519 DOI: 10.4161/cc.25016  0.8
2013 Wu K, Li Z, Cai S, Tian L, Chen K, Wang J, Hu J, Sun Y, Li X, Ertel A, Pestell RG. EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1. Cancer Research. 73: 4488-99. PMID 23636126 DOI: 10.1158/0008-5472.CAN-12-4078  0.4
2013 Shen D, Bai M, Tang R, Xu B, Ju X, Pestell RG, Achilefu S. Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity. Scientific Reports. 3: 1697. PMID 23603888 DOI: 10.1038/srep01697  0.8
2013 Quann K, Gonzales DM, Mercier I, Wang C, Sotgia F, Pestell RG, Lisanti MP, Jasmin JF. Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide Cell Cycle. 12: 1510-1520. PMID 23598719 DOI: 10.4161/cc.24497  0.8
2013 Avena P, Anselmo W, Whitaker-Menezes D, Wang C, Pestell RG, Lamb RS, Hulit J, Casaburi I, Andò S, Martinez-Outschoorn UE, Lisanti MP, Sotgia F. Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle (Georgetown, Tex.). 12: 1360-70. PMID 23574724 DOI: 10.4161/cc.24289  0.8
2013 Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, ... ... Pestell RG, et al. Dachshund binds p53 to block the growth of lung adenocarcinoma cells. Cancer Research. 73: 3262-74. PMID 23492369 DOI: 10.1158/0008-5472.CAN-12-3191  0.8
2013 Champ CE, Baserga R, Mishra MV, Jin L, Sotgia F, Lisanti MP, Pestell RG, Dicker AP, Simone NL. Nutrient restriction and radiation therapy for cancer treatment: when less is more. The Oncologist. 18: 97-103. PMID 23299773 DOI: 10.1634/theoncologist.2012-0164  0.8
2013 Trimmer C, Bonuccelli G, Katiyar S, Sotgia F, Pestell RG, Lisanti MP, Capozza F. Cav1 suppresses tumor growth and metastasis in a murine model of cutaneous SCC through modulation of MAPK/AP-1 activation. The American Journal of Pathology. 182: 992-1004. PMID 23267770 DOI: 10.1016/j.ajpath.2012.11.008  0.8
2013 Schild R, Knüppel T, Konrad M, Bergmann C, Trautmann A, Kemper MJ, Wu K, Yaklichkin S, Wang J, Pestell R, Müller-Wiefel DE, Schaefer F, Weber S. Double homozygous missense mutations in DACH1 and BMP4 in a patient with bilateral cystic renal dysplasia. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 28: 227-32. PMID 23262432 DOI: 10.1093/ndt/gfs539  0.8
2013 Ju X, Ertel A, Casimiro MC, Yu Z, Meng H, McCue PA, Walters R, Fortina P, Lisanti MP, Pestell RG. Novel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures. Cancer Research. 73: 978-89. PMID 23204233 DOI: 10.1158/0008-5472.CAN-12-2133  0.8
2013 Yu Z, Tozeren A, Pestell RG. Function of miRNAs in tumor cell proliferation Microrna in Cancer. 2147483647: 13-27. DOI: 10.1007/978-94-007-4655-8_2  0.8
2013 Wang C, Pestell TG, Pestell RG. A new perspective on cyclin D1: Beyond cell cycle regulation Cell and Molecular Biology of Breast Cancer. 289-304. DOI: 10.1007/978-1-62703-634-4_13  0.8
2012 Casimiro MC, Crosariol M, Loro E, Li Z, Pestell RG. Cyclins and cell cycle control in cancer and disease. Genes & Cancer. 3: 649-57. PMID 23634253 DOI: 10.1177/1947601913479022  0.8
2012 Myklebust MP, Li Z, Tran TH, Rui H, Knudsen ES, Elsaleh H, Fluge Ø, Vonen B, Myrvold HE, Leh S, Tveit KM, Pestell RG, Dahl O. Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer. British Journal of Cancer. 107: 1684-91. PMID 23099809 DOI: 10.1038/bjc.2012.463  0.8
2012 Yu Z, Li Y, Fan H, Liu Z, Pestell RG. miRNAs regulate stem cell self-renewal and differentiation. Frontiers in Genetics. 3: 191. PMID 23056008 DOI: 10.3389/fgene.2012.00191  0.8
2012 Yu Z, Pestell TG, Lisanti MP, Pestell RG. Cancer stem cells. The International Journal of Biochemistry & Cell Biology. 44: 2144-51. PMID 22981632 DOI: 10.1016/j.biocel.2012.08.022  0.8
2012 Capparelli C, Chiavarina B, Whitaker-Menezes D, Pestell TG, Pestell RG, Hulit J, Andò S, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis. Cell Cycle (Georgetown, Tex.). 11: 3599-610. PMID 22935696 DOI: 10.4161/cc.21884  0.8
2012 Carito V, Bonuccelli G, Martinez-Outschoorn UE, Whitaker-Menezes D, Caroleo MC, Cione E, Howell A, Pestell RG, Lisanti MP, Sotgia F. Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth. Cell Cycle (Georgetown, Tex.). 11: 3403-14. PMID 22918248 DOI: 10.4161/cc.21701  0.8
2012 Chiavarina B, Martinez-Outschoorn UE, Whitaker-Menezes D, Howell A, Tanowitz HB, Pestell RG, Sotgia F, Lisanti MP. Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells. Cell Cycle (Georgetown, Tex.). 11: 3280-9. PMID 22894905 DOI: 10.4161/cc.21643  0.8
2012 Guido C, Whitaker-Menezes D, Lin Z, Pestell RG, Howell A, Zimmers TA, Casimiro MC, Aquila S, Ando' S, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth. Oncotarget. 3: 798-810. PMID 22878233 DOI: 10.18632/oncotarget.574  0.8
2012 Guido C, Whitaker-Menezes D, Capparelli C, Balliet R, Lin Z, Pestell RG, Howell A, Aquila S, Andò S, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production. Cell Cycle (Georgetown, Tex.). 11: 3019-35. PMID 22874531 DOI: 10.4161/cc.21384  0.8
2012 Salem AF, Whitaker-Menezes D, Lin Z, Martinez-Outschoorn UE, Tanowitz HB, Al-Zoubi MS, Howell A, Pestell RG, Sotgia F, Lisanti MP. Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells. Cell Cycle (Georgetown, Tex.). 11: 2545-56. PMID 22722266 DOI: 10.4161/cc.20920  0.8
2012 Mercier I, Camacho J, Titchen K, Gonzales DM, Quann K, Bryant KG, Molchansky A, Milliman JN, Whitaker-Menezes D, Sotgia F, Jasmin JF, Schwarting R, Pestell RG, Blagosklonny MV, Lisanti MP. Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug. The American Journal of Pathology. 181: 278-93. PMID 22698676 DOI: 10.1016/j.ajpath.2012.03.017  0.8
2012 Capparelli C, Whitaker-Menezes D, Guido C, Balliet R, Pestell TG, Howell A, Sneddon S, Pestell RG, Martinez-Outschoorn U, Lisanti MP, Sotgia F. CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth. Cell Cycle (Georgetown, Tex.). 11: 2272-84. PMID 22684333 DOI: 10.4161/cc.20717  0.8
2012 Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle (Georgetown, Tex.). 11: 2285-302. PMID 22684298 DOI: 10.4161/cc.20718  0.8
2012 Velasco-Velázquez M, Jiao X, De La Fuente M, Pestell TG, Ertel A, Lisanti MP, Pestell RG. CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Research. 72: 3839-50. PMID 22637726 DOI: 10.1158/0008-5472.CAN-11-3917  0.8
2012 Casimiro MC, Pestell RG. Cyclin d1 induces chromosomal instability. Oncotarget. 3: 224-5. PMID 22538871 DOI: 10.18632/oncotarget.476  0.8
2012 Clark PM, Dawany N, Dampier W, Byers SW, Pestell RG, Tozeren A. Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases. Inflammatory Bowel Diseases. 18: 2315-33. PMID 22488912 DOI: 10.1002/ibd.22958  0.8
2012 Capozza F, Trimmer C, Castello-Cros R, Katiyar S, Whitaker-Menezes D, Follenzi A, Crosariol M, Llaverias G, Sotgia F, Pestell RG, Lisanti MP. Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration. Cancer Research. 72: 2262-74. PMID 22396494 DOI: 10.1158/0008-5472.CAN-11-2593  0.8
2012 Sotgia F, Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Philp NJ, Pestell RG, Lisanti MP. Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue. Cell Cycle (Georgetown, Tex.). 11: 1445-54. PMID 22395432 DOI: 10.4161/cc.19841  0.8
2012 Yu Z, Pestell RG. Small non-coding RNAs govern mammary gland tumorigenesis. Journal of Mammary Gland Biology and Neoplasia. 17: 59-64. PMID 22382486 DOI: 10.1007/s10911-012-9246-4  0.8
2012 Casimiro MC, Crosariol M, Loro E, Ertel A, Yu Z, Dampier W, Saria EA, Papanikolaou A, Stanek TJ, Li Z, Wang C, Fortina P, Addya S, Tozeren A, Knudsen ES, ... ... Pestell RG, et al. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice. The Journal of Clinical Investigation. 122: 833-43. PMID 22307325 DOI: 10.1172/JCI60256  0.76
2012 Velasco-Velázquez MA, Homsi N, De La Fuente M, Pestell RG. Breast cancer stem cells. The International Journal of Biochemistry & Cell Biology. 44: 573-7. PMID 22249027 DOI: 10.1016/j.biocel.2011.12.020  0.8
2012 Ertel A, Tsirigos A, Whitaker-Menezes D, Birbe RC, Pavlides S, Martinez-Outschoorn UE, Pestell RG, Howell A, Sotgia F, Lisanti MP. Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism. Cell Cycle (Georgetown, Tex.). 11: 253-63. PMID 22234241 DOI: 10.4161/cc.11.2.19006  0.8
2012 Katiyar S, Jiao X, Addya S, Ertel A, Covarrubias Y, Rose V, Casimiro MC, Zhou J, Lisanti MP, Nasim T, Fortina P, Pestell RG. Mammary gland selective excision of c-jun identifies its role in mRNA splicing. Cancer Research. 72: 1023-34. PMID 22174367 DOI: 10.1158/0008-5472.CAN-11-3647  0.8
2012 Sotgia F, Martinez-Outschoorn UE, Howell A, Pestell RG, Pavlides S, Lisanti MP. Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms. Annual Review of Pathology. 7: 423-67. PMID 22077552 DOI: 10.1146/annurev-pathol-011811-120856  0.8
2012 Pavlides S, Vera I, Gandara R, Sneddon S, Pestell RG, Mercier I, Martinez-Outschoorn UE, Whitaker-Menezes D, Howell A, Sotgia F, Lisanti MP. Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis. Antioxidants & Redox Signaling. 16: 1264-84. PMID 21883043 DOI: 10.1089/ars.2011.4243  0.8
2011 Ko YH, Lin Z, Flomenberg N, Pestell RG, Howell A, Sotgia F, Lisanti MP, Martinez-Outschoorn UE. Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance. Cancer Biology & Therapy. 12: 1085-97. PMID 22236876 DOI: 10.4161/cbt.12.12.18671  0.8
2011 Chiavarina B, Whitaker-Menezes D, Martinez-Outschoorn UE, Witkiewicz AK, Birbe R, Howell A, Pestell RG, Smith J, Daniel R, Sotgia F, Lisanti MP. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth. Cancer Biology & Therapy. 12: 1101-13. PMID 22236875 DOI: 10.4161/cbt.12.12.18703  0.8
2011 Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. Cell Cycle (Georgetown, Tex.). 10: 4047-64. PMID 22134189 DOI: 10.4161/cc.10.23.18151  0.8
2011 Montie HL, Pestell RG, Merry DE. SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17425-36. PMID 22131404 DOI: 10.1523/JNEUROSCI.3958-11.2011  0.8
2011 Balliet RM, Capparelli C, Guido C, Pestell TG, Martinez-Outschoorn UE, Lin Z, Whitaker-Menezes D, Chiavarina B, Pestell RG, Howell A, Sotgia F, Lisanti MP. Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection. Cell Cycle (Georgetown, Tex.). 10: 4065-73. PMID 22129993 DOI: 10.4161/cc.10.23.18254  0.8
2011 Martinez-Outschoorn UE, Goldberg A, Lin Z, Ko YH, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP. Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells. Cancer Biology & Therapy. 12: 924-38. PMID 22041887 DOI: 10.4161/cbt.12.10.17780  0.8
2011 Salem AF, Bonuccelli G, Bevilacqua G, Arafat H, Pestell RG, Sotgia F, Lisanti MP. Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition. Cell Cycle (Georgetown, Tex.). 10: 3692-700. PMID 22041584 DOI: 10.4161/cc.10.21.17895  0.8
2011 Martinez-Outschoorn UE, Pestell RG, Howell A, Tykocinski ML, Nagajyothi F, Machado FS, Tanowitz HB, Sotgia F, Lisanti MP. Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells. Cell Cycle (Georgetown, Tex.). 10: 4208-16. PMID 22033146 DOI: 10.4161/cc.10.24.18487  0.8
2011 Gravina GL, Marampon F, Piccolella M, Motta M, Ventura L, Pomante R, Popov VM, Zani BM, Pestell RG, Tombolini V, Jannini EA, Festuccia C. Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models. Endocrinology. 152: 4550-61. PMID 21990314 DOI: 10.1210/en.2011-1056  0.8
2011 Sotgia F, Martinez-Outschoorn UE, Pavlides S, Howell A, Pestell RG, Lisanti MP. Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment. Breast Cancer Research : Bcr. 13: 213. PMID 21867571 DOI: 10.1186/bcr2892  0.8
2011 Wang C, Powell M, Tian L, Pestell RG. Analysis of nuclear receptor acetylation. Methods in Molecular Biology (Clifton, N.J.). 776: 169-81. PMID 21796527 DOI: 10.1007/978-1-61779-243-4_11  0.8
2011 Martinez-Outschoorn UE, Lin Z, Trimmer C, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP. Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors. Cell Cycle (Georgetown, Tex.). 10: 2504-20. PMID 21778829 DOI: 10.4161/cc.10.15.16585  0.8
2011 Martinez-Outschoorn UE, Lin Z, Ko YH, Goldberg AF, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP. Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells. Cell Cycle (Georgetown, Tex.). 10: 2521-8. PMID 21768775 DOI: 10.4161/cc.10.15.16584  0.8
2011 Lisanti MP, Martinez-Outschoorn UE, Lin Z, Pavlides S, Whitaker-Menezes D, Pestell RG, Howell A, Sotgia F. Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer". Cell Cycle (Georgetown, Tex.). 10: 2440-9. PMID 21734470 DOI: 10.4161/cc.10.15.16870  0.8
2011 Velasco-Velázquez MA, Li Z, Casimiro M, Loro E, Homsi N, Pestell RG. Examining the role of cyclin D1 in breast cancer. Future Oncology (London, England). 7: 753-65. PMID 21675838 DOI: 10.2217/fon.11.56  0.8
2011 Lisanti MP, Martinez-Outschoorn UE, Pavlides S, Whitaker-Menezes D, Pestell RG, Howell A, Sotgia F. Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine. Cell Cycle (Georgetown, Tex.). 10: 2059-63. PMID 21654190 DOI: 10.4161/cc.10.13.16233  0.8
2011 Castello-Cros R, Bonuccelli G, Molchansky A, Capozza F, Witkiewicz AK, Birbe RC, Howell A, Pestell RG, Whitaker-Menezes D, Sotgia F, Lisanti MP. Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis. Cell Cycle (Georgetown, Tex.). 10: 2021-34. PMID 21646868 DOI: 10.4161/cc.10.12.16002  0.8
2011 Velasco-Velázquez MA, Popov VM, Lisanti MP, Pestell RG. The role of breast cancer stem cells in metastasis and therapeutic implications. The American Journal of Pathology. 179: 2-11. PMID 21640330 DOI: 10.1016/j.ajpath.2011.03.005  0.8
2011 Martinez-Outschoorn UE, Whitaker-Menezes D, Lin Z, Flomenberg N, Howell A, Pestell RG, Lisanti MP, Sotgia F. Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator. Cell Cycle (Georgetown, Tex.). 10: 1784-93. PMID 21566463 DOI: 10.4161/cc.10.11.15674  0.8
2011 Whitaker-Menezes D, Martinez-Outschoorn UE, Lin Z, Ertel A, Flomenberg N, Witkiewicz AK, Birbe RC, Howell A, Pavlides S, Gandara R, Pestell RG, Sotgia F, Philp NJ, Lisanti MP. Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 1772-83. PMID 21558814 DOI: 10.4161/cc.10.11.15659  0.8
2011 DeAngelis T, Wu K, Pestell R, Baserga R. The type 1 insulin-like growth factor receptor and resistance to DACH1. Cell Cycle (Georgetown, Tex.). 10: 1956-9. PMID 21558809 DOI: 10.4161/cc.10.12.15800  0.8
2011 Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics. Cell Cycle (Georgetown, Tex.). 10: 1271-86. PMID 21512313 DOI: 10.4161/cc.10.8.15330  0.8
2011 Janowski E, Jiao X, Katiyar S, Lisanti MP, Liu M, Pestell RG, Morad M. c-Jun is required for TGF-β-mediated cellular migration via nuclear Ca²⁺ signaling. The International Journal of Biochemistry & Cell Biology. 43: 1104-13. PMID 21447400 DOI: 10.1016/j.biocel.2011.03.011  0.8
2011 Martinez-Outschoorn UE, Pavlides S, Howell A, Pestell RG, Tanowitz HB, Sotgia F, Lisanti MP. Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment. The International Journal of Biochemistry & Cell Biology. 43: 1045-51. PMID 21300172 DOI: 10.1016/j.biocel.2011.01.023  0.8
2011 Marampon F, Gravina GL, Di Rocco A, Bonfili P, Di Staso M, Fardella C, Polidoro L, Ciccarelli C, Festuccia C, Popov VM, Pestell RG, Tombolini V, Zani BM. MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals. Molecular Cancer Therapeutics. 10: 159-68. PMID 21220498 DOI: 10.1158/1535-7163.MCT-10-0631  0.8
2011 Meng H, Tian L, Zhou J, Li Z, Jiao X, Li WW, Plomann M, Xu Z, Lisanti MP, Wang C, Pestell RG. PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b. Cell Cycle (Georgetown, Tex.). 10: 73-81. PMID 21200149 DOI: 10.4161/cc.10.1.14243  0.8
2011 Powell MJ, Casimiro MC, Cordon-Cardo C, He X, Yeow WS, Wang C, McCue PA, McBurney MW, Pestell RG. Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Research. 71: 964-75. PMID 21189328 DOI: 10.1158/0008-5472.CAN-10-3172  0.8
2011 Wang C, Tian L, Popov VM, Pestell RG. Acetylation and nuclear receptor action. The Journal of Steroid Biochemistry and Molecular Biology. 123: 91-100. PMID 21167281 DOI: 10.1016/j.jsbmb.2010.12.003  0.8
2011 Trimmer C, Sotgia F, Whitaker-Menezes D, Balliet RM, Eaton G, Martinez-Outschoorn UE, Pavlides S, Howell A, Iozzo RV, Pestell RG, Scherer PE, Capozza F, Lisanti MP. Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts. Cancer Biology & Therapy. 11: 383-94. PMID 21150282 DOI: 10.4161/cbt.11.4.14101  0.8
2011 Gaughan L, Stockley J, Wang N, McCracken SR, Treumann A, Armstrong K, Shaheen F, Watt K, McEwan IJ, Wang C, Pestell RG, Robson CN. Regulation of the androgen receptor by SET9-mediated methylation. Nucleic Acids Research. 39: 1266-79. PMID 20959290 DOI: 10.1093/nar/gkq861  0.8
2011 Wu K, Jiao X, Li Z, Katiyar S, Casimiro MC, Yang W, Zhang Q, Willmarth NE, Chepelev I, Crosariol M, Wei Z, Hu J, Zhao K, Pestell RG. Cell fate determination factor Dachshund reprograms breast cancer stem cell function Journal of Biological Chemistry. 286: 2132-2142. PMID 20937839 DOI: 10.1074/jbc.M110.148395  0.8
2011 Yu Z, Pestell RG. MicroRNAs and cancer stem cells Micrornas in Cancer Translational Research. 373-388. DOI: 10.1007/978-94-007-0298-1-16  0.8
2011 Powell MJ, Popov VM, Wang X, Mcmahon SB, Mazo A, Pestell RG. The Role of Epigenetic Modifications in Cancer Cancer Epigenetics: Biomolecular Therapeutics For Human Cancer. 113-144. DOI: 10.1002/9781118005743.ch7  0.8
2010 Liu M, Sakamaki T, Casimiro MC, Willmarth NE, Quong AA, Ju X, Ojeifo J, Jiao X, Yeow WS, Katiyar S, Shirley LA, Joyce D, Lisanti MP, Albanese C, Pestell RG. The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion. Cancer Research. 70: 10464-73. PMID 21159656 DOI: 10.1158/0008-5472.CAN-10-0732  0.8
2010 Gravina GL, Festuccia C, Marampon F, Popov VM, Pestell RG, Zani BM, Tombolini V. Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation. Molecular Cancer. 9: 305. PMID 21108789 DOI: 10.1186/1476-4598-9-305  0.8
2010 Martinez-Outschoorn UE, Whitaker-Menezes D, Pavlides S, Chiavarina B, Bonuccelli G, Casey T, Tsirigos A, Migneco G, Witkiewicz A, Balliet R, Mercier I, Wang C, Flomenberg N, Howell A, Lin Z, ... ... Pestell RG, et al. The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox. Cell Cycle (Georgetown, Tex.). 9: 4297-306. PMID 21051947 DOI: 10.4161/cc.9.21.13817  0.8
2010 Zhou J, Liu Y, Zhang W, Popov VM, Wang M, Pattabiraman N, Suñé C, Cvekl A, Wu K, Jiang J, Wang C, Pestell RG. Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. The Journal of Biological Chemistry. 285: 40342-50. PMID 20956529 DOI: 10.1074/jbc.M110.156141  0.8
2010 Li Z, Jiao X, Wang C, Shirley LA, Elsaleh H, Dahl O, Wang M, Soutoglou E, Knudsen ES, Pestell RG. Alternative cyclin D1 splice forms differentially regulate the DNA damage response. Cancer Research. 70: 8802-11. PMID 20940395 DOI: 10.1158/0008-5472.CAN-10-0312  0.8
2010 Katiyar S, Casimiro MC, Dettin L, Ju X, Wagner EF, Tanaka H, Pestell RG. C-jun inhibits mammary apoptosis in vivo. Molecular Biology of the Cell. 21: 4264-74. PMID 20926681 DOI: 10.1091/mbc.E10-08-0705  0.8
2010 Pavlides S, Tsirigos A, Migneco G, Whitaker-Menezes D, Chiavarina B, Flomenberg N, Frank PG, Casimiro MC, Wang C, Pestell RG, Martinez-Outschoorn UE, Howell A, Sotgia F, Lisanti MP. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism. Cell Cycle (Georgetown, Tex.). 9: 3485-505. PMID 20861672 DOI: 10.4161/cc.9.17.12721  0.8
2010 Martinez-Outschoorn UE, Trimmer C, Lin Z, Whitaker-Menezes D, Chiavarina B, Zhou J, Wang C, Pavlides S, Martinez-Cantarin MP, Capozza F, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Caro J, et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment. Cell Cycle (Georgetown, Tex.). 9: 3515-33. PMID 20855962 DOI: 10.4161/cc.9.17.12928  0.8
2010 Bonuccelli G, Tsirigos A, Whitaker-Menezes D, Pavlides S, Pestell RG, Chiavarina B, Frank PG, Flomenberg N, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism. Cell Cycle (Georgetown, Tex.). 9: 3506-14. PMID 20818174 DOI: 10.4161/cc.9.17.12731  0.8
2010 Martinez-Outschoorn UE, Balliet RM, Rivadeneira DB, Chiavarina B, Pavlides S, Wang C, Whitaker-Menezes D, Daumer KM, Lin Z, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Knudsen ES, Sotgia F, et al. Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells. Cell Cycle (Georgetown, Tex.). 9: 3256-76. PMID 20814239 DOI: 10.4161/cc.9.16.12553  0.8
2010 Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, ... ... Pestell RG, et al. Dietary restriction: standing up for sirtuins. Science (New York, N.Y.). 329: 1012-3; author reply. PMID 20798296 DOI: 10.1126/science.329.5995.1012  0.8
2010 Trimmer C, Whitaker-Menezes D, Bonuccelli G, Milliman JN, Daumer KM, Aplin AE, Pestell RG, Sotgia F, Lisanti MP, Capozza F. CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway. Cancer Research. 70: 7489-99. PMID 20709760 DOI: 10.1158/0008-5472.CAN-10-0900  0.8
2010 Migneco G, Whitaker-Menezes D, Chiavarina B, Castello-Cros R, Pavlides S, Pestell RG, Fatatis A, Flomenberg N, Tsirigos A, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling. Cell Cycle (Georgetown, Tex.). 9: 2412-22. PMID 20562527 DOI: 10.4161/cc.9.12.11989  0.8
2010 Martinez-Outschoorn UE, Pavlides S, Whitaker-Menezes D, Daumer KM, Milliman JN, Chiavarina B, Migneco G, Witkiewicz AK, Martinez-Cantarin MP, Flomenberg N, Howell A, Pestell RG, Lisanti MP, Sotgia F. Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors. Cell Cycle (Georgetown, Tex.). 9: 2423-33. PMID 20562526 DOI: 10.4161/cc.9.12.12048  0.8
2010 Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation. Cell Cycle (Georgetown, Tex.). 9: 2201-19. PMID 20519932 DOI: 10.4161/cc.9.11.11848  0.8
2010 Bonuccelli G, Whitaker-Menezes D, Castello-Cros R, Pavlides S, Pestell RG, Fatatis A, Witkiewicz AK, Vander Heiden MG, Migneco G, Chiavarina B, Frank PG, Capozza F, Flomenberg N, Martinez-Outschoorn UE, Sotgia F, et al. The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts. Cell Cycle (Georgetown, Tex.). 9: 1960-71. PMID 20495363 DOI: 10.4161/cc.9.10.11601  0.8
2010 Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Pestell RG, Martinez-Outschoorn UE, Howell A, Sotgia F, Lisanti MP. Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling". Aging. 2: 185-99. PMID 20442453 DOI: v2/n4/full/100134.html  0.8
2010 Yu Z, Willmarth NE, Zhou J, Katiyar S, Wang M, Liu Y, McCue PA, Quong AA, Lisanti MP, Pestell RG. microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 8231-6. PMID 20406904 DOI: 10.1073/pnas.1002080107  0.8
2010 Vissapragada S, Ghosh A, Ringer L, Salinas P, Brophy A, Peaceman D, Kallakury B, Banerjee PP, Fricke ST, Helfrich W, Lee YC, Pestell R, Scherer P, Tanowitz HB, Avantaggiati ML, et al. Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model. Cell Cycle (Georgetown, Tex.). 9: 1824-9. PMID 20404514 DOI: 10.4161/cc.9.9.11542  0.8
2010 Zhou J, Wang C, Wang Z, Dampier W, Wu K, Casimiro MC, Chepelev I, Popov VM, Quong A, Tozeren A, Zhao K, Lisanti MP, Pestell RG. Attenuation of Forkhead signaling by the retinal determination factor DACH1 Proceedings of the National Academy of Sciences of the United States of America. 107: 6864-6869. PMID 20351289 DOI: 10.1073/pnas.1002746107  0.8
2010 Yu Z, Baserga R, Chen L, Wang C, Lisanti MP, Pestell RG. microRNA, cell cycle, and human breast cancer. The American Journal of Pathology. 176: 1058-64. PMID 20075198 DOI: 10.2353/ajpath.2010.090664  0.8
2010 Jiao X, Katiyar S, Willmarth NE, Liu M, Ma X, Flomenberg N, Lisanti MP, Pestell RG. c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion. The Journal of Biological Chemistry. 285: 8218-26. PMID 20053993 DOI: 10.1074/jbc.M110.100792  0.8
2010 Thakur ML, Devadhas D, Zhang K, Pestell RG, Wang C, McCue P, Wickstrom E. Imaging spontaneous MMTVneu transgenic murine mammary tumors: targeting metabolic activity versus genetic products. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 106-11. PMID 20008985 DOI: 10.2967/jnumed.109.069542  0.8
2010 Popov VM, Wu K, Zhou J, Powell MJ, Mardon G, Wang C, Pestell RG. The Dachshund gene in development and hormone-responsive tumorigenesis. Trends in Endocrinology and Metabolism: Tem. 21: 41-9. PMID 19896866 DOI: 10.1016/j.tem.2009.08.002  0.8
2010 Ma Y, Fan S, Hu C, Meng Q, Fuqua SA, Pestell RG, Tomita YA, Rosen EM. BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha. Molecular Endocrinology (Baltimore, Md.). 24: 76-90. PMID 19887647 DOI: 10.1210/me.2009-0218  0.8
2009 Tian L, Zhou J, Casimiro MC, Liang B, Ojeifo JO, Wang M, Hyslop T, Wang C, Pestell RG. Activating peroxisome proliferator-activated receptor gamma mutant promotes tumor growth in vivo by enhancing angiogenesis. Cancer Research. 69: 9236-44. PMID 19934321 DOI: 10.1158/0008-5472.CAN-09-2067  0.8
2009 Pavlides S, Whitaker-Menezes D, Castello-Cros R, Flomenberg N, Witkiewicz AK, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma. Cell Cycle (Georgetown, Tex.). 8: 3984-4001. PMID 19923890  0.8
2009 Genander M, Halford MM, Xu NJ, Eriksson M, Yu Z, Qiu Z, Martling A, Greicius G, Thakar S, Catchpole T, Chumley MJ, Zdunek S, Wang C, Holm T, Goff SP, ... ... Pestell RG, et al. Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression. Cell. 139: 679-92. PMID 19914164 DOI: 10.1016/j.cell.2009.08.048  0.8
2009 Popov VM, Zhou J, Shirley LA, Quong J, Yeow WS, Wright JA, Wu K, Rui H, Vadlamudi RK, Jiang J, Kumar R, Wang C, Pestell RG. The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling. Cancer Research. 69: 5752-60. PMID 19605405 DOI: 10.1158/0008-5472.CAN-08-3992  0.8
2009 Zhou J, Zhang W, Liang B, Casimiro MC, Whitaker-Menezes D, Wang M, Lisanti MP, Lanza-Jacoby S, Pestell RG, Wang C. PPARgamma activation induces autophagy in breast cancer cells. The International Journal of Biochemistry & Cell Biology. 41: 2334-42. PMID 19563910 DOI: 10.1016/j.biocel.2009.06.007  0.8
2009 Di Vizio D, Morello M, Sotgia F, Pestell RG, Freeman MR, Lisanti MP. An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation. Cell Cycle (Georgetown, Tex.). 8: 2420-4. PMID 19556867  0.8
2009 Witkiewicz AK, Dasgupta A, Nguyen KH, Liu C, Kovatich AJ, Schwartz GF, Pestell RG, Sotgia F, Rui H, Lisanti MP. Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer. Cancer Biology & Therapy. 8: 1071-9. PMID 19502809 DOI: 10.4161/cbt.8.11.8874  0.8
2009 Nan F, Lü Q, Zhou J, Cheng L, Popov VM, Wei S, Kong B, Pestell RG, Lisanti MP, Jiang J, Wang C. Altered expression of DACH1 and cyclin D1 in endometrial cancer. Cancer Biology & Therapy. 8: 1534-9. PMID 19502783 DOI: 10.4161/cbt.8.16.8963  0.8
2009 Witkiewicz AK, Casimiro MC, Dasgupta A, Mercier I, Wang C, Bonuccelli G, Jasmin JF, Frank PG, Pestell RG, Kleer CG, Sotgia F, Lisanti MP. Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy. Cell Cycle (Georgetown, Tex.). 8: 1654-8. PMID 19448435  0.8
2009 Witkiewicz AK, Dasgupta A, Sotgia F, Mercier I, Pestell RG, Sabel M, Kleer CG, Brody JR, Lisanti MP. An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers. The American Journal of Pathology. 174: 2023-34. PMID 19411448 DOI: 10.2353/ajpath.2009.080873  0.8
2009 Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, ... ... Pestell RG, et al. Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature. The American Journal of Pathology. 174: 1650-62. PMID 19395651 DOI: 10.2353/ajpath.2009.080648  0.8
2009 Wu K, Katiyar S, Witkiewicz A, Li A, McCue P, Song LN, Tian L, Jin M, Pestell RG. The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth. Cancer Research. 69: 3347-55. PMID 19351840 DOI: 10.1158/0008-5472.CAN-08-3821  0.4
2009 Liu M, Ju X, Willmarth NE, Casimiro MC, Ojeifo J, Sakamaki T, Katiyar S, Jiao X, Popov VM, Yu Z, Wu K, Joyce D, Wang C, Pestell RG. Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. The American Journal of Pathology. 174: 1910-20. PMID 19349372 DOI: 10.2353/ajpath.2009.080706  0.8
2009 Mercier I, Bryant KG, Sotgia F, Bonuccelli G, Witkiewicz AK, Dasgupta A, Jasmin JF, Pestell RG, Lisanti MP. Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation Cell Cycle. 8: 1396-1401. PMID 19342880 DOI: 10.4161/cc.8.9.8307  0.8
2009 Mercier I, Casimiro MC, Zhou J, Wang C, Plymire C, Bryant KG, Daumer KM, Sotgia F, Bonuccelli G, Witkiewicz AK, Lin J, Tran TH, Milliman J, Frank PG, Jasmin JF, ... ... Pestell RG, et al. Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions. The American Journal of Pathology. 174: 1172-90. PMID 19342371 DOI: 10.2353/ajpath.2009.080882  0.8
2009 Mercier I, Jasmin JF, Pavlides S, Minetti C, Flomenberg N, Pestell RG, Frank PG, Sotgia F, Lisanti MP. Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 614-23. PMID 19333235 DOI: 10.1038/labinvest.2009.23  0.8
2009 Velasco-Velázquez MA, Yu Z, Jiao X, Pestell RG. Cancer stem cells and the cell cycle: Targeting the drive behind breast cancer Expert Review of Anticancer Therapy. 9: 275-279. PMID 19275505 DOI: 10.1586/14737140.9.3.275  0.8
2009 Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, ... ... Pestell RG, et al. Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts. The American Journal of Pathology. 174: 746-61. PMID 19234134 DOI: 10.2353/ajpath.2009.080658  0.8
2009 Sotgia F, Casimiro MC, Bonuccelli G, Liu M, Whitaker-Menezes D, Er O, Daumer KM, Mercier I, Witkiewicz AK, Minetti C, Capozza F, Gormley M, Quong AA, Rui H, Frank PG, ... ... Pestell RG, et al. Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation. The American Journal of Pathology. 174: 613-29. PMID 19164602 DOI: 10.2353/ajpath.2009.080653  0.8
2008 Lindsay J, Jiao X, Sakamaki T, Casimiro MC, Shirley LA, Tran TH, Ju X, Liu M, Li Z, Wang C, Katiyar S, Rao M, Allen KG, Glazer RI, Ge C, ... ... Pestell RG, et al. ErbB2 induces Notch1 activity and function in breast cancer cells. Clinical and Translational Science. 1: 107-15. PMID 20443831 DOI: 10.1111/j.1752-8062.2008.00041.x  0.8
2008 Augustus AS, Buchanan J, Gutman E, Rengo G, Pestell RG, Fortina P, Koch WJ, Bensadoun A, Abel ED, Lisanti MP. Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism Cell Cycle. 7: 2509-2518. PMID 18719368 DOI: 10.4161/cc.7.16.6421  0.8
2008 Yu Z, Wang C, Wang M, Li Z, Casimiro MC, Liu M, Wu K, Whittle J, Ju X, Hyslop T, McCue P, Pestell RG. A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. The Journal of Cell Biology. 182: 509-17. PMID 18695042 DOI: 10.1083/jcb.200801079  0.8
2008 Pezo RC, Gandhi SJ, Shirley LA, Pestell RG, Augenlicht LH, Singer RH. Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors. Cancer Research. 68: 4977-82. PMID 18593893 DOI: 10.1158/0008-5472.CAN-07-6770  0.8
2008 Kim M, Wu X, Song I, Fu M, Chang SH, Lisanti MP, Pestell R. Selective cytotoxicity of synthesized procyanidin 3-O-galloylepicatechin- 4b, 8-3-O-galloylcatechin to human cancer cells Cell Cycle. 7: 1648-1657. PMID 18560275  0.8
2008 Augustus AS, Buchanan J, Addya S, Rengo G, Pestell RG, Fortina P, Koch WJ, Bensadoun A, Abel ED, Lisanti MP. Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts American Journal of Physiology - Heart and Circulatory Physiology. 295: H657-H666. PMID 18552160 DOI: 10.1152/ajpheart.00387.2008  0.8
2008 Mercier I, Vuolo M, Jasmin JF, Medina CM, Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP, Kitsis RN. ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer Cell Cycle. 7: 1640-1647. PMID 18469522 DOI: 10.4161/cc.7.11.5979  0.8
2008 Wu K, Katiyar S, Li A, Liu M, Ju X, Popov VM, Jiao X, Lisanti MP, Casola A, Pestell RG. Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. Proceedings of the National Academy of Sciences of the United States of America. 105: 6924-9. PMID 18467491 DOI: 10.1073/pnas.0802085105  0.8
2008 Mercier I, Casimiro MC, Wang C, Rosenberg AL, Quong J, Minkeu A, Allen KG, Danilo C, Sotgia F, Bonuccelli G, Jasmin JF, Xu H, Bosco E, Aronow B, Witkiewicz A, ... Pestell RG, et al. Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy Cancer Biology and Therapy. 7: 1212-1225. PMID 18458534 DOI: 10.4161/cbt.7.8.6220  0.8
2008 Marampon F, Casimiro MC, Fu M, Powell MJ, Popov VM, Lindsay J, Zani BM, Ciccarelli C, Watanabe G, Lee RJ, Pestell RG. Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB. Molecular Biology of the Cell. 19: 2566-78. PMID 18367547 DOI: 10.1091/mbc.E06-12-1110  0.8
2008 Rao M, Casimiro MC, Lisanti MP, D'Amico M, Wang C, Shirley LA, Leader JE, Liu M, Stallcup M, Engel DA, Murphy DJ, Pestell RG. Inhibition of cyclin D1 gene transcription by Brg-1. Cell Cycle (Georgetown, Tex.). 7: 647-55. PMID 18239461  0.8
2008 Bouzahzah B, Yurchenko V, Nagajyothi F, Hulit J, Sadofsky M, Braunstein VL, Mukherjee S, Weiss H, Machado FS, Pestell RG, Lisanti MP, Tanowitz HB, Albanese C. Regulation of host cell cyclin D1 by Trypanosoma cruzi in myoblasts. Cell Cycle (Georgetown, Tex.). 7: 500-3. PMID 18239452 DOI: 10.4161/cc.7.4.5327  0.8
2008 Jiao X, Katiyar S, Liu M, Mueller SC, Lisanti MP, Li A, Pestell TG, Wu K, Ju X, Li Z, Wagner EF, Takeya T, Wang C, Pestell RG. Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase. Molecular Biology of the Cell. 19: 1378-90. PMID 18216279 DOI: 10.1091/mbc.E07-08-0753  0.8
2008 Li Z, Wang C, Jiao X, Katiyar S, Casimiro MC, Prendergast GC, Powell MJ, Pestell RG. Alternate cyclin D1 mRNA splicing modulates p27KIP1 binding and cell migration. The Journal of Biological Chemistry. 283: 7007-15. PMID 18180298 DOI: 10.1074/jbc.M706992200  0.8
2008 Wang C, Powell MJ, Popov VM, Pestell RG. Acetylation in nuclear receptor signaling and the role of sirtuins. Molecular Endocrinology (Baltimore, Md.). 22: 539-45. PMID 18165438 DOI: 10.1210/me.2007-0379  0.8
2008 Sundaram K, Mani SK, Kitatani K, Wu K, Pestell RG, Reddy SV. DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells. Journal of Cellular Biochemistry. 103: 1747-59. PMID 17891780 DOI: 10.1002/jcb.21561  0.8
2007 Whittle JR, Powell MJ, Popov VM, Shirley LA, Wang C, Pestell RG. Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation. Trends in Endocrinology and Metabolism: Tem. 18: 356-64. PMID 17964799 DOI: 10.1016/j.tem.2007.07.007  0.8
2007 Di Vizio D, Sotgia F, Williams TM, Hassan GS, Capozza F, Frank PG, Pestell RG, Loda M, Freeman MR, Lisanti MP. Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression. Cancer Biology & Therapy. 6: 1263-8. PMID 17786030  0.8
2007 Pavithra L, Rampalli S, Sinha S, Sreenath K, Pestell RG, Chattopadhyay S. Stabilization of SMAR1 mRNA by PGA2 involves a stem-loop structure in the 5′ UTR Nucleic Acids Research. 35: 6004-6016. PMID 17726044 DOI: 10.1093/nar/gkm649  0.8
2007 Avvisato CL, Yang X, Shah S, Hoxter B, Li W, Gaynor R, Pestell R, Tozeren A, Byers SW. Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells. Journal of Cell Science. 120: 2672-82. PMID 17635998 DOI: 10.1242/jcs.03476  0.8
2007 Casimiro M, Rodriguez O, Pootrakul L, Aventian M, Lushina N, Cromelin C, Ferzli G, Johnson K, Fricke S, Diba F, Kallakury B, Ohanyerenwa C, Chen M, Ostrowski M, Hung MC, ... ... Pestell R, et al. ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo. Cancer Research. 67: 4364-72. PMID 17483350 DOI: 10.1158/0008-5472.CAN-06-1898  0.8
2007 Ju X, Katiyar S, Wang C, Liu M, Jiao X, Li S, Zhou J, Turner J, Lisanti MP, Russell RG, Mueller SC, Ojeifo J, Chen WS, Hay N, Pestell RG. Akt1 governs breast cancer progression in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 7438-43. PMID 17460049 DOI: 10.1073/pnas.0605874104  0.8
2007 Ozaki I, Zhang H, Mizuta T, Ide Y, Eguchi Y, Yasutake T, Sakamaki T, Pestell RG, Yamamoto K. Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor kappaB activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2236-45. PMID 17404108 DOI: 10.1158/1078-0432.CCR-06-2308  0.68
2007 Popov VM, Wang C, Shirley LA, Rosenberg A, Li S, Nevalainen M, Fu M, Pestell RG. The functional significance of nuclear receptor acetylation. Steroids. 72: 221-30. PMID 17291555 DOI: 10.1016/j.steroids.2006.12.001  0.8
2007 Wu K, Liu M, Li A, Donninger H, Rao M, Jiao X, Lisanti MP, Cvekl A, Birrer M, Pestell RG. Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Molecular Biology of the Cell. 18: 755-67. PMID 17182846 DOI: 10.1091/mbc.E06-09-0793  0.8
2007 Katiyar S, Jiao X, Wagner E, Lisanti MP, Pestell RG. Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor Molecular and Cellular Biology. 27: 1356-1369. PMID 17145782 DOI: 10.1128/MCB.01061-06  0.8
2006 Leader JE, Wang C, Popov VM, Fu M, Pestell RG. Epigenetics and the estrogen receptor. Annals of the New York Academy of Sciences. 1089: 73-87. PMID 17261756 DOI: 10.1196/annals.1386.047  0.8
2006 Sotgia F, Rui H, Bonuccelli G, Mercier I, Pestell RG, Lisanti MP. Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers. Cancer Research. 66: 10647-51. PMID 17108100 DOI: 10.1158/0008-5472.CAN-06-2805  0.8
2006 Li Z, Wang C, Prendergast GC, Pestell RG. Cyclin D1 functions in cell migration. Cell Cycle (Georgetown, Tex.). 5: 2440-2. PMID 17106256 DOI: 10.4161/cc.5.21.3428  0.8
2006 Bouzahzah B, Nagajyothi F, Desruisseaux MS, Krishnamachary M, Factor SM, Cohen AW, Lisanti MP, Petkova SB, Pestell RG, Wittner M, Mukherjee S, Weiss LM, Jelicks LA, Albanese C, Tanowitz HB. Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection. Cell Cycle (Georgetown, Tex.). 5: 2396-400. PMID 17102609 DOI: 10.4161/cc.5.20.3380  0.8
2006 Williams TM, Sotgia F, Lee H, Hassan G, Di Vizio D, Bonuccelli G, Capozza F, Mercier I, Rui H, Pestell RG, Lisanti MP. Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells. The American Journal of Pathology. 169: 1784-801. PMID 17071600 DOI: 10.2353/ajpath.2006.060590  0.8
2006 Medina FA, de Almeida CJ, Dew E, Li J, Bonuccelli G, Williams TM, Cohen AW, Pestell RG, Frank PG, Tanowitz HB, Lisanti MP. Caveolin-1-deficient mice show defects in innate immunity and inflammatory immune response during Salmonella enterica serovar Typhimurium infection. Infection and Immunity. 74: 6665-74. PMID 16982844 DOI: 10.1128/IAI.00949-06  0.8
2006 Wu K, Li A, Rao M, Liu M, Dailey V, Yang Y, Di Vizio D, Wang C, Lisanti MP, Sauter G, Russell RG, Cvekl A, Pestell RG. DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth. Molecular and Cellular Biology. 26: 7116-29. PMID 16980615 DOI: 10.1128/MCB.00268-06  0.8
2006 Hulit J, Lee RJ, Li Z, Wang C, Katiyar S, Yang J, Quong AA, Wu K, Albanese C, Russell R, Di Vizio D, Koff A, Thummala S, Zhang H, Harrell J, ... ... Pestell RG, et al. p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling. Cancer Research. 66: 8529-41. PMID 16951165 DOI: 10.1158/0008-5472.CAN-06-0149  0.8
2006 Sunde JS, Donninger H, Wu K, Johnson ME, Pestell RG, Rose GS, Mok SC, Brady J, Bonome T, Birrer MJ. Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer. Cancer Research. 66: 8404-12. PMID 16951150 DOI: 10.1158/0008-5472.CAN-06-0683  0.8
2006 Fu M, Liu M, Sauve AA, Jiao X, Zhang X, Wu X, Powell MJ, Yang T, Gu W, Avantaggiati ML, Pattabiraman N, Pestell TG, Wang F, Quong AA, Wang C, ... Pestell RG, et al. Hormonal control of androgen receptor function through SIRT1. Molecular and Cellular Biology. 26: 8122-35. PMID 16923962 DOI: 10.1128/MCB.00289-06  0.8
2006 Pestell RG, Li Z. Antisense to cyclin D1 inhibits VEGF-stimulated growth of vascular endothelial cells: Implication of tumor vascularization Clinical Cancer Research. 12: 4459-4462. PMID 16899588 DOI: 10.1158/1078-0432.CCR-06-0614  0.8
2006 Stahl M, Ge C, Shi S, Pestell RG, Stanley P. Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1. Cancer Research. 66: 7562-70. PMID 16885355 DOI: 10.1158/0008-5472.CAN-06-0974  0.8
2006 Wang C, Li Z, Lu Y, Du R, Katiyar S, Yang J, Fu M, Leader JE, Quong A, Novikoff PM, Pestell RG. Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 103: 11567-72. PMID 16864783 DOI: 10.1073/pnas.0603363103  0.68
2006 Leader JE, Wang C, Fu M, Pestell RG. Epigenetic regulation of nuclear steroid receptors Biochemical Pharmacology. 72: 1589-1596. PMID 16844098 DOI: 10.1016/j.bcp.2006.05.024  0.8
2006 Sakamaki T, Casimiro MC, Ju X, Quong AA, Katiyar S, Liu M, Jiao X, Li A, Zhang X, Lu Y, Wang C, Byers S, Nicholson R, Link T, Shemluck M, ... ... Pestell R, et al. Cyclin D1 determines mitochondrial function in vivo. Molecular and Cellular Biology. 26: 5449-69. PMID 16809779 DOI: 10.1128/MCB.02074-05  0.8
2006 Chang YJ, Wu MS, Lin JT, Pestell RG, Blaser MJ, Chen CC. Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle Cellular Microbiology. 8: 1740-1752. PMID 16759223 DOI: 10.1111/j.1462-5822.2006.00743.x  0.8
2006 Li T, Sotgia F, Vuolo MA, Li M, Yang WC, Pestell RG, Sparano JA, Lisanti MP. Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status. The American Journal of Pathology. 168: 1998-2013. PMID 16723714  0.8
2006 Li Z, Wang C, Jiao X, Lu Y, Fu M, Quong AA, Dye C, Yang J, Dai M, Ju X, Zhang X, Li A, Burbelo P, Stanley ER, Pestell RG. Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. Molecular and Cellular Biology. 26: 4240-56. PMID 16705174 DOI: 10.1128/MCB.02124-05  0.68
2006 Yang T, Fu M, Pestell R, Sauve AA. SIRT1 and endocrine signaling. Trends in Endocrinology and Metabolism: Tem. 17: 186-91. PMID 16684606 DOI: 10.1016/j.tem.2006.04.002  0.8
2006 Yang Y, Stopka T, Golestaneh N, Wang Y, Wu K, Li A, Chauhan BK, Gao CY, Cveklová K, Duncan MK, Pestell RG, Chepelinsky AB, Skoultchi AI, Cvekl A. Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin. The Embo Journal. 25: 2107-18. PMID 16675956 DOI: 10.1038/sj.emboj.7601114  0.8
2006 Seki Y, Yamamoto H, Ngan CY, Yasui M, Tomita N, Kitani K, Takemasa I, Ikeda M, Sekimoto M, Matsuura N, Albanese C, Kaneda Y, Pestell RG, Monden M. Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway. Molecular Cancer Therapeutics. 5: 985-94. PMID 16648570 DOI: 10.1158/1535-7163.MCT-05-0388  0.8
2006 Cui Y, Niu A, Pestell R, Kumar R, Curran EM, Liu Y, Fuqua SA. Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 20: 2020-35. PMID 16645043 DOI: 10.1210/me.2005-0063  0.8
2006 Pestell R. Remembering team science is for the patients Cancer Biology and Therapy. 5: 449-452. PMID 16575209  0.8
2006 Leslie K, Lang C, Devgan G, Azare J, Berishaj M, Gerald W, Kim YB, Paz K, Darnell JE, Albanese C, Sakamaki T, Pestell R, Bromberg J. Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Research. 66: 2544-52. PMID 16510571 DOI: 10.1158/0008-5472.CAN-05-2203  0.8
2006 Sourisseau T, Georgiadis A, Tsapara A, Ali RR, Pestell R, Matter K, Balda MS. Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA Molecular and Cellular Biology. 26: 2387-2398. PMID 16508013 DOI: 10.1128/MCB.26.6.2387-2398.2006  0.8
2006 Sotgia F, Schubert W, Pestell RG, Lisanti MP. Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyper-activates STAT5a signaling Cancer Biology and Therapy. 5: 292-297. PMID 16418573  0.8
2006 Sotgia F, Williams TM, Schubert W, Medina F, Minetti C, Pestell RG, Lisanti MP. Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. The American Journal of Pathology. 168: 292-309. PMID 16400031 DOI: 10.2353/ajpath.2006.050429  0.8
2006 Hassan GS, Mukherjee S, Nagajyothi F, Weiss LM, Petkova SB, de Almeida CJ, Huang H, Desruisseaux MS, Bouzahzah B, Pestell RG, Albanese C, Christ GJ, Lisanti MP, Tanowitz HB. Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells. Infection and Immunity. 74: 152-9. PMID 16368968 DOI: 10.1128/IAI.74.1.152-159.2006  0.8
2006 Yin Y, Yuan H, Wang C, Pattabiraman N, Rao M, Pestell RG, Glazer RI. 3-Phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor- and promotes adipocyte differentiation Molecular Endocrinology. 20: 268-278. PMID 16150867 DOI: 10.1210/me.2005-0197  0.8
2005 Li J, Hassan GS, Williams TM, Minetti C, Pestell RG, Tanowitz HB, Frank PG, Sotgia F, Lisanti MP. Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation. Cell Cycle (Georgetown, Tex.). 4: 1817-25. PMID 16294037  0.8
2005 Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP. Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling. Cell Cycle (Georgetown, Tex.). 4: 1808-16. PMID 16294019  0.8
2005 Xiao D, Chinnappan D, Pestell R, Albanese C, Weber HC. Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells Cancer Research. 65: 9934-9942. PMID 16267018 DOI: 10.1158/0008-5472.CAN-05-1830  0.8
2005 Wang C, Fan S, Li Z, Fu M, Rao M, Ma Y, Lisanti MP, Albanese C, Katzenellenbogen BS, Kushner PJ, Weber B, Rosen EM, Pestell RG. Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity. Cancer Research. 65: 6557-67. PMID 16061635 DOI: 10.1158/0008-5472.CAN-05-0486  0.8
2005 Lewis JS, Vijayanathan V, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T. Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2. Oncology Research. 15: 113-28. PMID 16050133  0.8
2005 Wu K, D'Amico M, Wang C, Albanese C, Pestell RG, Mani S. A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines. Investigational New Drugs. 23: 299-309. PMID 16012789 DOI: 10.1007/s10637-005-1438-y  0.8
2005 Fu M, Wang C, Rao M, Wu X, Bouras T, Zhang X, Li Z, Jiao X, Yang J, Li A, Perkins ND, Thimmapaya B, Kung AL, Munoz A, Giordano A, ... ... Pestell RG, et al. Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism. The Journal of Biological Chemistry. 280: 29728-42. PMID 15951563 DOI: 10.1074/jbc.M503188200  0.8
2005 Giampuzzi M, Oleggini R, Albanese C, Pestell R, Di Donato A. beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase. Biochimica Et Biophysica Acta. 1745: 370-81. PMID 15946752 DOI: 10.1016/j.bbamcr.2005.04.012  0.8
2005 Ho YS, Chen CH, Wang YJ, Pestell RG, Albanese C, Chen RJ, Chang MC, Jeng JH, Lin SY, Liang YC, Tseng H, Lee WS, Lin JK, Chu JS, Chen LC, et al. Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation. Toxicology and Applied Pharmacology. 205: 133-48. PMID 15893541 DOI: 10.1016/j.taap.2004.09.019  0.68
2005 Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, Lee H, Temple K, Graves R, Pollard J, Chopra N, Russell RG, Sasisekharan R, Trock BJ, Lippman M, ... ... Pestell RG, et al. Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. The Journal of Clinical Investigation. 115: 1163-76. PMID 15841211 DOI: 10.1172/JCI23424  0.8
2005 Williams TM, Hassan GS, Li J, Cohen AW, Medina F, Frank PG, Pestell RG, Di Vizio D, Loda M, Lisanti MP. Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice. The Journal of Biological Chemistry. 280: 25134-45. PMID 15802273 DOI: 10.1074/jbc.M501186200  0.8
2005 Song DH, Kaufman JC, Borodyansky L, Albanese C, Pestell RG, Wolfe MM. Gastrin stabilises beta-catenin protein in mouse colorectal cancer cells. British Journal of Cancer. 92: 1581-7. PMID 15798764 DOI: 10.1038/sj.bjc.6602509  0.8
2005 Fu M, Rao M, Bouras T, Wang C, Wu K, Zhang X, Li Z, Yao TP, Pestell RG. Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. The Journal of Biological Chemistry. 280: 16934-41. PMID 15713663 DOI: 10.1074/jbc.M500403200  0.68
2005 Moadel RM, Weldon RH, Katz EB, Lu P, Mani J, Stahl M, Blaufox MD, Pestell RG, Charron MJ, Dadachova E. Positherapy: targeted nuclear therapy of breast cancer with 18F-2-deoxy-2-fluoro-D-glucose. Cancer Research. 65: 698-702. PMID 15705862  0.8
2005 Lewis JS, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T. Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells. Journal of Molecular Endocrinology. 34: 91-105. PMID 15691880 DOI: 10.1677/jme.1.01599  0.8
2005 Fan S, Gao M, Meng Q, Laterra JJ, Symons MH, Coniglio S, Pestell RG, Goldberg ID, Rosen EM. Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection. Oncogene. 24: 1749-66. PMID 15688034 DOI: 10.1038/sj.onc.1208327  0.8
2005 Bouras T, Fu M, Sauve AA, Wang F, Quong AA, Perkins ND, Hay RT, Gu W, Pestell RG. SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. The Journal of Biological Chemistry. 280: 10264-76. PMID 15632193 DOI: 10.1074/jbc.M408748200  0.8
2004 Hilakivi-Clarke L, Wang C, Kalil M, Riggins R, Pestell RG. Nutritional modulation of the cell cycle and breast cancer Endocrine-Related Cancer. 11: 603-622. PMID 15613442 DOI: 10.1677/erc.1.00665  0.8
2004 Cui Y, Zhang M, Pestell R, Curran EM, Welshons WV, Fuqua SAW. Phosphorylation of estrogen receptor α blocks its acetylation and regulates estrogen sensitivity Cancer Research. 64: 9199-9208. PMID 15604293 DOI: 10.1158/0008-5472.CAN-04-2126  0.8
2004 Bouras T, Lisanti MP, Pestell RG. Caveolin-1 in breast cancer Cancer Biology and Therapy. 3: 931-941. PMID 15539932  0.8
2004 Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP. Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. The Journal of Biological Chemistry. 279: 51630-46. PMID 15355971 DOI: 10.1074/jbc.M409214200  0.8
2004 Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. Minireview: Cyclin D1: Normal and abnormal functions Endocrinology. 145: 5439-5447. PMID 15331580 DOI: 10.1210/en.2004-0959  0.8
2004 Guha U, Mecklenburg L, Cowin P, Kan L, O'Guin WM, D'Vizio D, Pestell RG, Paus R, Kessler JA. Bone morphogenetic protein signaling regulates postnatal hair follicle differentiation and cycling. The American Journal of Pathology. 165: 729-40. PMID 15331398 DOI: 10.1016/S0002-9440(10)63336-6  0.8
2004 Mukherjee S, Huang H, Petkova SB, Albanese C, Pestell RG, Braunstein VL, Christ GJ, Wittner M, Lisanti MP, Berman JW, Weiss LM, Tanowitz HB. Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells. Infection and Immunity. 72: 5274-82. PMID 15322023 DOI: 10.1128/IAI.72.9.5274-5282.2004  0.8
2004 Liu MC, Marshall JL, Pestell RG. Novel strategies in cancer therapeutics: Targeting enzymes involved in cell cycle regulation and cellular proliferation Current Cancer Drug Targets. 4: 403-424. PMID 15320717 DOI: 10.2174/1568009043332907  0.8
2004 Hulit J, Wang C, Li Z, Albanese C, Rao M, Di Vizio D, Shah S, Byers SW, Mahmood R, Augenlicht LH, Russell R, Pestell RG. Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Molecular and Cellular Biology. 24: 7598-611. PMID 15314168 DOI: 10.1128/MCB.25.1.523.2005  0.68
2004 Fu M, Wang C, Zhang X, Pestell RG. Acetylation of nuclear receptors in cellular growth and apoptosis. Biochemical Pharmacology. 68: 1199-208. PMID 15313417 DOI: 10.1016/j.bcp.2004.05.037  0.8
2004 D'Amico M, Wu K, Fu M, Rao M, Albanese C, Russell RG, Lian H, Bregman D, White MA, Pestell RG. The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements. Cancer Research. 64: 4122-30. PMID 15205322 DOI: 10.1158/0008-5472.CAN-03-2519  0.68
2004 Fu M, Wang C, Zhang X, Pestell RG. Signal transduction inhibitors in cellular function. Methods in Molecular Biology (Clifton, N.J.). 284: 15-36. PMID 15173606 DOI: 10.1385/1-59259-816-1:015  0.8
2004 Wang C, Li Z, Fu M, Bouras T, Pestell RG. Signal transduction mediated by cyclin D1: from mitogens to cell proliferation: a molecular target with therapeutic potential Cancer Treatment and Research. 119: 217-237. PMID 15164880  0.8
2004 Fu M, Rao M, Wu K, Wang C, Zhang X, Hessien M, Yeung YG, Gioeli D, Weber MJ, Pestell RG. The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity. The Journal of Biological Chemistry. 279: 29436-49. PMID 15123687 DOI: 10.1074/jbc.M313466200  0.68
2004 Pradeep A, Sharma C, Sathyanarayana P, Albanese C, Fleming JV, Wang TC, Wolfe MM, Baker KM, Pestell RG, Rana B. Gastrin-mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells. Oncogene. 23: 3689-99. PMID 15116100 DOI: 10.1038/sj.onc.1207454  0.8
2004 Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP. Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. The Journal of Biological Chemistry. 279: 24745-56. PMID 15044451 DOI: 10.1074/jbc.M402064200  0.8
2004 Burbelo P, Wellstein A, Pestell RG. Altered Rho GTPase signaling pathways in breast cancer cells. Breast Cancer Research and Treatment. 84: 43-8. PMID 14999153 DOI: 10.1023/B:BREA.0000018422.02237.f9  0.8
2004 Wang C, Fu M, Pestell RG. Histone acetylation/deacetylation as a regulator of cell cycle gene expression Methods in Molecular Biology (Clifton, N.J.). 241: 207-216. PMID 14970656  0.8
2004 Sharma C, Pradeep A, Pestell RG, Rana B. Peroxisome Proliferator-activated Receptor γ Activation Modulates Cyclin D1 Transcription via β-Catenin-independent and cAMP-response Element-binding Protein-dependent Pathways in Mouse Hepatocytes Journal of Biological Chemistry. 279: 16927-16938. PMID 14764597 DOI: 10.1074/jbc.M309045200  0.8
2004 Bateman NW, Tan D, Pestell RG, Black JD, Black AR. Intestinal tumor progression is associated with altered function of KLF5. The Journal of Biological Chemistry. 279: 12093-101. PMID 14726538 DOI: 10.1074/jbc.M311532200  0.8
2004 Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK, Kumar R. p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. The Journal of Biological Chemistry. 279: 1422-8. PMID 14530270 DOI: 10.1074/jbc.M309937200  0.8
2003 Xiong J, Fan S, Meng Q, Schramm L, Wang C, Bouzahza B, Zhou J, Zafonte B, Goldberg ID, Haddad BR, Pestell RG, Rosen EM. BRCA1 inhibition of telomerase activity in cultured cells. Molecular and Cellular Biology. 23: 8668-90. PMID 14612409 DOI: 10.1128/MCB.23.23.8668-8690.2003  0.8
2003 Fu M, Rao M, Wang C, Sakamaki T, Wang J, Di Vizio D, Zhang X, Albanese C, Balk S, Chang C, Fan S, Rosen E, Palvimo JJ, Jänne OA, Muratoglu S, ... ... Pestell RG, et al. Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth. Molecular and Cellular Biology. 23: 8563-75. PMID 14612401 DOI: 10.1128/MCB.23.23.8563-8575.2003  0.68
2003 Cai D, Iyer A, Felekkis KN, Near RI, Luo Z, Chernoff J, Albanese C, Pestell RG, Lerner A. AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter. Cancer Research. 63: 6802-8. PMID 14583477  0.8
2003 Wu K, Yang Y, Wang C, Davoli MA, D'Amico M, Li A, Cveklova K, Kozmik Z, Lisanti MP, Russell RG, Cvekl A, Pestell RG. DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. The Journal of Biological Chemistry. 278: 51673-84. PMID 14525983 DOI: 10.1074/jbc.M310021200  0.8
2003 Rosen EM, Fan S, Pestell RG, Goldberg ID. BRCA1 in hormone-responsive cancers. Trends in Endocrinology and Metabolism: Tem. 14: 378-85. PMID 14516936 DOI: 10.1016/j.tem.2003.08.001  0.8
2003 Iyengar P, Combs TP, Shah SJ, Gouon-Evans V, Pollard JW, Albanese C, Flanagan L, Tenniswood MP, Guha C, Lisanti MP, Pestell RG, Scherer PE. Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization. Oncogene. 22: 6408-23. PMID 14508521 DOI: 10.1038/sj.onc.1206737  0.8
2003 Rowlands TM, Pechenkina IV, Hatsell SJ, Pestell RG, Cowin P. Dissecting the roles of β-catenin and cyclin D1 during mammary development and neoplasia Proceedings of the National Academy of Sciences of the United States of America. 100: 11400-11405. PMID 13679587 DOI: 10.1073/pnas.1534601100  0.8
2003 Shah S, Hecht A, Pestell R, Byers SW. Trans-repression of beta-catenin activity by nuclear receptors. The Journal of Biological Chemistry. 278: 48137-45. PMID 12972427 DOI: 10.1074/jbc.M307154200  0.8
2003 Fu M, Wang C, Zhang X, Pestell R. Nuclear receptor modifications and endocrine cell proliferation. The Journal of Steroid Biochemistry and Molecular Biology. 85: 133-8. PMID 12943697 DOI: 10.1016/S0960-0760(03)00223-1  0.8
2003 Wang C, Pattabiraman N, Zhou JN, Fu M, Sakamaki T, Albanese C, Li Z, Wu K, Hulit J, Neumeister P, Novikoff PM, Brownlee M, Scherer PE, Jones JG, Whitney KD, ... ... Pestell RG, et al. Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation. Molecular and Cellular Biology. 23: 6159-73. PMID 12917338 DOI: 10.1128/MCB.23.17.6159-6173.2003  0.8
2003 D'Amico M, Wu K, Di Vizio D, Reutens AT, Stahl M, Fu M, Albanese C, Russell RG, Muller WJ, White M, Negassa A, Lee HW, DePinho RA, Pestell RG. The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis. Cancer Research. 63: 3395-402. PMID 12810676  0.8
2003 Neumeister P, Pixley FJ, Xiong Y, Xie H, Wu K, Ashton A, Cammer M, Chan A, Symons M, Stanley ER, Pestell RG. Cyclin D1 governs adhesion and motility of macrophages. Molecular Biology of the Cell. 14: 2005-15. PMID 12802071 DOI: 10.1091/mbc.02-07-0102  0.8
2003 Rosen EM, Fan S, Pestell RG, Goldberg ID. BRCA1 gene in breast cancer. Journal of Cellular Physiology. 196: 19-41. PMID 12767038 DOI: 10.1002/jcp.10257  0.8
2003 Hu YL, Albanese C, Pestell RG, Jaffe RB. Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells. Journal of the National Cancer Institute. 95: 733-40. PMID 12759391  0.8
2003 Huang E, Ishida S, Pittman J, Dressman H, Bild A, Kloos M, D'Amico M, Pestell RG, West M, Nevins JR. Gene expression phenotypic models that predict the activity of oncogenic pathways. Nature Genetics. 34: 226-30. PMID 12754511 DOI: 10.1038/ng1167  0.8
2003 Nelsen CJ, Rickheim DG, Tucker MM, McKenzie TJ, Hansen LK, Pestell RG, Albrecht JH. Amino acids regulate hepatocyte proliferation through modulation of cyclin D1 expression Journal of Biological Chemistry. 278: 25853-25858. PMID 12736274 DOI: 10.1074/jbc.M302360200  0.8
2003 Huang H, Petkova SB, Cohen AW, Bouzahzah B, Chan J, Zhou JN, Factor SM, Weiss LM, Krishnamachary M, Mukherjee S, Wittner M, Kitsis RN, Pestell RG, Lisanti MP, Albanese C, et al. Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis. Infection and Immunity. 71: 2859-67. PMID 12704159 DOI: 10.1128/IAI.71.5.2859-2867.2003  0.8
2003 Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP. Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice. Molecular Biology of the Cell. 14: 1027-42. PMID 12631721 DOI: 10.1091/mbc.E02-08-0503  0.8
2003 Song DH, Rana B, Wolfe JR, Crimmins G, Choi C, Albanese C, Wang TC, Pestell RG, Wolfe MM. Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G217-22. PMID 12606305 DOI: 10.1152/ajpgi.00516.2002  0.8
2003 Albanese C, Wu K, D'Amico M, Jarrett C, Joyce D, Hughes J, Hulit J, Sakamaki T, Fu M, Ben-Ze'ev A, Bromberg JF, Lamberti C, Verma U, Gaynor RB, Byers SW, ... Pestell RG, et al. IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. Molecular Biology of the Cell. 14: 585-99. PMID 12589056 DOI: 10.1091/mbc.02-06-0101  0.68
2003 Xian Ma Y, Fan S, Xiong J, Yuan RQ, Meng Q, Gao M, Goldberg ID, Fuqua SA, Pestell RG, Rosen EM. Role of BRCA1 in heat shock response. Oncogene. 22: 10-27. PMID 12527903 DOI: 10.1038/sj.onc.1206061  0.8
2002 Coulter CL, Pestell RG, Ross JT, Salkeld MD, James S, Bennett HPJ, McMillen IC. Effect of n-proopiomelanocortin (1-77) and (1-49) infusions on adrenal expression of cyclin d1 in the fetal sheep Endocrine Research. 28: 625-629. PMID 12530673 DOI: 10.1081/ERC-120016976  0.8
2002 Lin W, Albanese C, Pestell RG, Lawrence DS. Spatially discrete, light-driven protein expression. Chemistry & Biology. 9: 1347-53. PMID 12498888 DOI: 10.1016/S1074-5521(02)00288-0  0.8
2002 Fu M, Wang C, Wang J, Zafonte BT, Lisanti MP, Pestell RG. Acetylation in hormone signaling and the cell cycle. Cytokine & Growth Factor Reviews. 13: 259-76. PMID 12486878 DOI: 10.1016/S1359-6101(02)00003-5  0.8
2002 Wu K, Wang C, D'Amico M, Lee RJ, Albanese C, Pestell RG, Mani S. Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways. Molecular Cancer Therapeutics. 1: 695-706. PMID 12479366  0.8
2002 Lin HM, Pestell RG, Raz A, Kim HRC. Galectin-3 enhances cyclin D1 promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells Oncogene. 21: 8001-8010. PMID 12439750 DOI: 10.1038/sj.onc.1205820  0.8
2002 Park DS, Lee H, Frank PG, Razani B, Nguyen AV, Parlow AF, Russell RG, Hulit J, Pestell RG, Lisanti MP. Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. Molecular Biology of the Cell. 13: 3416-30. PMID 12388746 DOI: 10.1091/mbc.02-05-0071  0.8
2002 Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. The American Journal of Pathology. 161: 1357-69. PMID 12368209 DOI: 10.1016/S0002-9440(10)64412-4  0.8
2002 Albanese C, Hulit J, Sakamaki T, Pestell RG. Recent advances in inducible expression in transgenic mice. Seminars in Cell & Developmental Biology. 13: 129-41. PMID 12240598 DOI: 10.1016/S1084-9521(02)00021-6  0.8
2002 Holnthoner W, Pillinger M, Groger M, Wolff K, Ashton AW, Albanese C, Neumeister P, Pestell RG, Petzelbauer P. Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells. The Journal of Biological Chemistry. 277: 45847-53. PMID 12235165 DOI: 10.1074/jbc.M209354200  0.68
2002 Guha U, Gomes WA, Kobayashi T, Pestell RG, Kessler JA. In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb. Developmental Biology. 249: 108-20. PMID 12217322 DOI: 10.1006/dbio.2002.0752  0.8
2002 Hulit J, Lee RJ, Russell RG, Pestell RG. ErbB-2-induced mammary tumor growth: The role of cyclin D1 and p27Kip1 Biochemical Pharmacology. 64: 827-836. PMID 12213576 DOI: 10.1016/S0006-2952(02)01145-0  0.8
2002 Neumeister P, Albanese C, Balent B, Greally J, Pestell RG. Senescence and epigenetic dysregulation in cancer. The International Journal of Biochemistry & Cell Biology. 34: 1475-90. PMID 12200040 DOI: 10.1016/S1357-2725(02)00079-1  0.8
2002 Huang H, Yanagisawa M, Kisanuki YY, Jelicks LA, Chandra M, Factor SM, Wittner M, Weiss LM, Pestell RG, Shtutin V, Shirani J, Tanowitz HB. Role of cardiac myocyte-derived endothelin-1 in chagasic cardiomyopathy: molecular genetic evidence. Clinical Science (London, England : 1979). 103: 263S-266S. PMID 12193100 DOI: 10.1042/CS103S263S  0.8
2002 Page K, Li J, Corbit KC, Rumilla KM, Soh JW, Weinstein IB, Albanese C, Pestell RG, Rosner MR, Hershenson MB. Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta. American Journal of Respiratory Cell and Molecular Biology. 27: 204-13. PMID 12151312 DOI: 10.1165/ajrcmb.27.2.20010016oc  0.8
2002 Zhang ZK, Davies KP, Allen J, Zhu L, Pestell RG, Zagzag D, Kalpana GV. Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Molecular and Cellular Biology. 22: 5975-88. PMID 12138206 DOI: 10.1128/MCB.22.16.5975-5988.2002  0.8
2002 Suzui M, Masuda M, Lim JT, Albanese C, Pestell RG, Weinstein IB. Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1. Cancer Research. 62: 3997-4006. PMID 12124333  0.8
2002 Kim MO, Si Q, Zhou JN, Pestell RG, Brosnan CF, Locker J, Lee SC. Interferon-beta activates multiple signaling cascades in primary human microglia. Journal of Neurochemistry. 81: 1361-71. PMID 12068083 DOI: 10.1046/j.1471-4159.2002.00949.x  0.8
2002 Tanaka H, Matsumura I, Ezoe S, Satoh Y, Sakamaki T, Albanese C, Machii T, Pestell RG, Kanakura Y. E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination. Molecular Cell. 9: 1017-29. PMID 12049738 DOI: 10.1016/S1097-2765(02)00522-1  0.68
2002 Shivakumar L, Minna J, Sakamaki T, Pestell R, White MA. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation Molecular and Cellular Biology. 22: 4309-4318. PMID 12024041 DOI: 10.1128/MCB.22.12.4309-4318.2002  0.8
2002 Liu MM, Albanese C, Anderson CM, Hilty K, Webb P, Uht RM, Price RH, Pestell RG, Kushner PJ. Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression. The Journal of Biological Chemistry. 277: 24353-60. PMID 11986316 DOI: 10.1074/jbc.M201829200  0.8
2002 Fu M, Wang C, Wang J, Zhang X, Sakamaki T, Yeung YG, Chang C, Hopp T, Fuqua SA, Jaffray E, Hay RT, Palvimo JJ, Jänne OA, Pestell RG. Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. Molecular and Cellular Biology. 22: 3373-88. PMID 11971970 DOI: 10.1128/MCB.22.10.3373-3388.2002  0.8
2002 Bearss DJ, Lee RJ, Troyer DA, Pestell RG, Windle JJ. Differential effects of p21WAF1/CIP1 deficiency on MMTV-ras and MMTV-myc mammary tumor properties Cancer Research. 62: 2077-2084. PMID 11929828  0.8
2002 Amanatullah DF, Zafonte BT, Pestell RG. The cell cycle in steroid hormone regulated proliferation and differentiation Minerva Endocrinologica. 27: 7-20. PMID 11845110  0.8
2002 Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP. Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. The Journal of Biological Chemistry. 277: 16464-9. PMID 11815623 DOI: 10.1074/jbc.M112274200  0.8
2002 Dadachova E, Bouzahzah B, Zuckier LS, Pestell RG. Rhenium-188 as an alternative to Iodine-131 for treatment of breast tumors expressing the sodium/iodide symporter (NIS) Nuclear Medicine and Biology. 29: 13-18. PMID 11786271 DOI: 10.1016/S0969-8051(01)00279-7  0.8
2002 Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, Hull MA. Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis. 23: 107-14. PMID 11756231  0.8
2002 Neumeister P, Pestell R, Balent B, Jaeger G, Linkesch W, Sill H. Myelodysplastic syndrome: Etiology, prognosis and management American Journal of Cancer. 1: 301-311. DOI: 10.2165/00024669-200201050-00001  0.8
2001 Zhao J, Pestell R, Guan JL. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression Molecular Biology of the Cell. 12: 4066-4077. PMID 11739801 DOI: 10.1091/MBC.12.12.4066  0.8
2001 Beier F, Ali Z, Mok D, Taylor AC, Leask T, Albanese C, Pestell RG, LuValle P. TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression. Molecular Biology of the Cell. 12: 3852-63. PMID 11739785 DOI: 10.1091/mbc.12.12.3852  0.68
2001 Park DS, Lee H, Riedel C, Hulit J, Scherer PE, Pestell RG, Lisanti MP. Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism. The Journal of Biological Chemistry. 276: 48389-97. PMID 11602600 DOI: 10.1074/jbc.M108210200  0.8
2001 Schlegel A, Wang C, Pestell RG, Lisanti MP. Ligand-independent activation of oestrogen receptor alpha by caveolin-1. The Biochemical Journal. 359: 203-10. PMID 11563984 DOI: 10.1042/0264-6021:3590203  0.8
2001 Fan S, Yuan RQ, Ma YX, Xiong J, Meng Q, Erdos M, Zhao JN, Goldberg ID, Pestell RG, Rosen EM. Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding Oncogene. 20: 4827-4841. PMID 11521194 DOI: 10.1038/sj.onc.1204666  0.8
2001 Galbiati F, Volonte' D, Liu J, Capozza F, Frank PG, Zhu L, Pestell RG, Lisanti MP. Caveolin-1 expression negatively regulates cell cycle progression by inducing G0/G1 arrest via a p53/p21WAF1/Cip1-dependent mechanism Molecular Biology of the Cell. 12: 2229-2244. PMID 11514613 DOI: 10.1091/mbc.12.8.2229  0.8
2001 Sampson EM, Haque ZK, Ku MC, Tevosian SG, Albanese C, Pestell RG, Paulson KE, Yee AS. Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. The Embo Journal. 20: 4500-11. PMID 11500377 DOI: 10.1093/emboj/20.16.4500  0.8
2001 Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H, Kneitz B, Lagaud G, Christ GJ, et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. The Journal of Biological Chemistry. 276: 38121-38. PMID 11457855 DOI: 10.1074/jbc.M105408200  0.8
2001 Hulit J, Di Vizio D, Pestell RG. Inducible transgenics. New lessons on events governing the induction and commitment in mammary tumorigenesis Breast Cancer Research. 3: 209-212. PMID 11434870 DOI: 10.1186/bcr297  0.8
2001 Zafonte BT, Amanatullah DF, Sage D, Augenlicht LH, Pestell RG. Ras regulation of cyclin-dependent immunoprecipitation kinase assays Methods in Enzymology. 333: 127-138. PMID 11400330 DOI: 10.1016/S0076-6879(01)33051-3  0.8
2001 Amanatullah DF, Zafonte BT, Albanese C, Fu M, Messiers C, Hassell J, Pestell RG. Ras regulation of cyclin D1 promoter Methods in Enzymology. 333: 116-127. PMID 11400329 DOI: 10.1016/S0076-6879(01)33050-1  0.8
2001 Allan AL, Albanese C, Pestell RG, LaMarre J. Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes. The Journal of Biological Chemistry. 276: 27272-80. PMID 11375399 DOI: 10.1074/jbc.M103196200  0.8
2001 Petkova SB, Huang H, Factor SM, Pestell RG, Bouzahzah B, Jelicks LA, Weiss LM, Douglas SA, Wittner M, Tanowitz HB. The role of endothelin in the pathogenesis of Chagas' disease International Journal For Parasitology. 31: 499-511. PMID 11334935 DOI: 10.1016/S0020-7519(01)00168-0  0.8
2001 Condeelis JS, Wyckoff JB, Bailly M, Pestell R, Lawrence D, Backer J, Segall JE. Lamellipodia in invasion Seminars in Cancer Biology. 11: 119-128. PMID 11322831 DOI: 10.1006/scbi.2000.0363  0.8
2001 Lin HM, Lee YJ, Li G, Pestell RG, Kim HRC. Bcl-2 induces cyclin D1 promoter activity in human breast epithelial cells independent of cell anchorage Cell Death and Differentiation. 8: 44-50. PMID 11313702 DOI: 10.1038/sj.cdd.4400770  0.8
2001 Joyce D, Albanese C, Steer J, Fu M, Bouzahzah B, Pestell RG. NF-κB and cell-cycle regulation: The cyclin connection Cytokine and Growth Factor Reviews. 12: 73-90. PMID 11312120 DOI: 10.1016/S1359-6101(00)00018-6  0.8
2001 Wang C, Fu M, D'Amico M, Albanese C, Zhou JN, Brownlee M, Lisanti MP, Chatterjee VK, Lazar MA, Pestell RG. Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. Molecular and Cellular Biology. 21: 3057-70. PMID 11287611 DOI: 10.1128/MCB.21.9.3057-3070.2001  0.8
2001 Wang C, Fu M, Mani S, Wadler S, Senderowicz AM, Pestell RG. Histone acetylation and the cell-cycle in cancer Frontiers in Bioscience : a Journal and Virtual Library. 6. PMID 11282573  0.8
2001 Wang C, Fu M, Angeletti RH, Siconolfi-Baez L, Reutens AT, Albanese C, Lisanti MP, Katzenellenbogen BS, Kato S, Hopp T, Fuqua SA, Lopez GN, Kushner PJ, Pestell RG. Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. The Journal of Biological Chemistry. 276: 18375-83. PMID 11279135 DOI: 10.1074/jbc.M100800200  0.8
2001 Soriano S, Kang DE, Fu M, Pestell R, Chevallier N, Zheng H, Koo EH. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing. The Journal of Cell Biology. 152: 785-94. PMID 11266469 DOI: 10.1083/jcb.152.4.785  0.8
2001 Park DS, Razani B, Lasorella A, Schreiber-Agus N, Pestell RG, Iavarone A, Lisanti MP. Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism. Biochemistry. 40: 3354-62. PMID 11258956 DOI: 10.1021/bi002787b  0.8
2001 Fan S, Ma YX, Wang C, Yuan RQ, Meng Q, Wang JA, Erdos M, Goldberg ID, Webb P, Kushner PJ, Pestell RG, Rosen EM. Role of direct interaction in BRCA1 inhibition of estrogen receptor activity Oncogene. 20: 77-87. PMID 11244506 DOI: 10.1038/sj.onc.1204073  0.8
2001 Volonté D, Galbiati F, Pestell RG, Lisanti MP. Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr14) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress Journal of Biological Chemistry. 276: 8094-8103. PMID 11094059 DOI: 10.1074/jbc.M009245200  0.8
2000 Wang C, Francis R, Harirchian S, Batlle D, Mayhew B, Bassett M, Rainey WE, Pestell RG. The application of high density microarray for analysis of mitogenic signaling and cell-cycle in the adrenal Endocrine Research. 26: 807-823. PMID 11196458 DOI: 10.3109/07435800009048604  0.8
2000 Zafonte BT, Hulit J, Amanatullah DF, Albanese C, Wang C, Rosen E, Reutens A, Sparano JA, Lisanti MP, Pestell RG. Cell-cycle dysregulation in breast cancer: breast cancer therapies targeting the cell cycle Frontiers in Bioscience : a Journal and Virtual Library. 5. PMID 11102317 DOI: 10.2741/zafonte  0.8
2000 Schlegel A, Pestell RG, Lisanti MP. Caveolins in cholesterol trafficking and signal transduction: implications for human disease. Frontiers in Bioscience : a Journal and Virtual Library. 5: D929-37. PMID 11102315  0.8
2000 Huang H, Petkova SB, Pestell RG, Bouzahzah B, Chan J, Magazine H, Weiss LM, Christ GJ, Lisanti MP, Douglas SA, Shtutin V, Halonen SK, Wittner M, Tanowitz HB. Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium. Journal of Cardiovascular Pharmacology. 36: S148-50. PMID 11078362 DOI: 10.1097/00005344-200036051-00046  0.8
2000 Razani B, Altschuler Y, Zhu L, Pestell RG, Mostov KE, Lisanti MP. Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation. Biochemistry. 39: 13916-24. PMID 11076533 DOI: 10.1021/bi001489b  0.8
2000 Lee H, Volonte D, Galbiati F, Iyengar P, Lublin DM, Bregman DB, Wilson MT, Campos-Gonzalez R, Bouzahzah B, Pestell RG, Scherer PE, Lisanti MP. Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette. Molecular Endocrinology (Baltimore, Md.). 14: 1750-75. PMID 11075810 DOI: 10.1210/mend.14.11.0553  0.8
2000 Bailly M, Wyckoff J, Bouzahzah B, Hammerman R, Sylvestre V, Cammer M, Pestell R, Segall JE. Epidermal growth factor receptor distribution during chemotactic responses. Molecular Biology of the Cell. 11: 3873-83. PMID 11071913 DOI: 10.1091/MBC.11.11.3873  0.8
2000 Petkova SB, Tanowitz HB, Magazine HI, Factor SM, Chan J, Pestell RG, Bouzahzah B, Douglas SA, Shtutin V, Morris SA, Tsang E, Weiss LM, Christ GJ, Wittner M, Huang H. Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 9: 257-65. PMID 11064272 DOI: 10.1016/S1054-8807(00)00045-4  0.8
2000 Mani S, Wang C, Wu K, Francis R, Pestell R. Cyclin-dependent kinase inhibitors: Novel anticancer agents Expert Opinion On Investigational Drugs. 9: 1849-1870. PMID 11060782  0.8
2000 Yu B, Lane ME, Pestell RG, Albanese C, Wadler S. Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein Molecular Cell Biology Research Communications. 3: 352-359. PMID 11032757 DOI: 10.1006/mcbr.2000.0238  0.8
2000 Henry DO, Moskalenko SA, Kaur KJ, Fu M, Pestell RG, Camonis JH, White MA. Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB. Molecular and Cellular Biology. 20: 8084-92. PMID 11027278 DOI: 10.1128/MCB.20.21.8084-8092.2000  0.8
2000 Page K, Li J, Wang Y, Kartha S, Pestell RG, Hershenson MB. Regulation of cyclin D(1) expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 23: 436-43. PMID 11017907 DOI: 10.1165/ajrcmb.23.4.3953  0.8
2000 Pruitt K, Pestell RG, Der CJ. Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells. The Journal of Biological Chemistry. 275: 40916-24. PMID 11007784 DOI: 10.1074/jbc.M006682200  0.8
2000 Shie JL, Chen ZY, O'Brien MJ, Pestell RG, Lee ME, Tseng CC. Role of gut-enriched Kruppel-like factor in colonic cell growth and differentiation American Journal of Physiology - Gastrointestinal and Liver Physiology. 279. PMID 11005769  0.8
2000 Bouzahzah B, Fu M, Iavarone A, Factor VM, Thorgeirsson SS, Pestell RG. Transforming growth factor-β1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo Cancer Research. 60: 4531-4537. PMID 10969803  0.8
2000 Galbiati F, Volonte D, Chu JB, Li M, Fine SW, Fu M, Bermudez J, Pedemonte M, Weidenheim KM, Pestell RG, Minetti C, Lisanti MP. Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype. Proceedings of the National Academy of Sciences of the United States of America. 97: 9689-94. PMID 10931944 DOI: 10.1073/pnas.160249097  0.8
2000 D'Amico M, Hulit J, Amanatullah DF, Zafonte BT, Albanese C, Bouzahzah B, Fu M, Augenlicht LH, Donehower LA, Takemaru KI, Moon RT, Davis R, Lisanti MP, Shtutman M, Zhurinsky J, ... ... Pestell RG, et al. The integrated-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3β and cAMP-responsive element-binding protein-dependent pathways Journal of Biological Chemistry. 275: 32649-32657. PMID 10915780 DOI: 10.1074/jbc.M000643200  0.8
2000 Shie JL, Chen ZY, Fu M, Pestell RG, Tseng CC. Gut-enriched Kruppel-like factor represess cyclin D1 promoter activity through Sp1 motif Nucleic Acids Research. 28: 2969-2976. PMID 10908361  0.8
2000 Zahler MH, Irani A, Malhi H, Reutens AT, Albanese C, Bouzahzah B, Joyce D, Gupta S, Pestell RG. The application of a lentiviral vector for gene transfer in fetal human hepatocytes Journal of Gene Medicine. 2: 186-193. PMID 10894264 DOI: 10.1002/(SICI)1521-2254(200005/06)2:3<186::AID-JGM100>3.0.CO;2-6  0.8
2000 Albanese C, Reutens AT, Bouzahzah B, Fu M, D'Amico M, Link T, Nicholson R, Depinho RA, Pestell RG. Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 877-84. PMID 10783141 DOI: 10.1096/fasebj.14.7.877  0.68
2000 Petkova SB, Ashton A, Bouzahzah B, Huang H, Pestell RG, Tanowitz HB. Cell cycle molecules and diseases of the cardiovascular system Frontiers in Bioscience : a Journal and Virtual Library. 5. PMID 10762598  0.8
2000 Amanatullah DF, Reutens AT, Zafonte BT, Fu M, Mani S, Pestell RG. Cell-cycle dysregulation and the molecular mechanisms of prostate cancer Frontiers in Bioscience : a Journal and Virtual Library. 5. PMID 10762592  0.8
2000 Lin SY, Xia W, Wang JC, Kwong KY, Spohn B, Wen Y, Pestell RG, Hung MC. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 97: 4262-6. PMID 10759547 DOI: 10.1073/pnas.060025397  0.8
2000 Zhang W, Razani B, Altschuler Y, Bouzahzah B, Mostov KE, Pestell RG, Lisanti MP. Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1. The Journal of Biological Chemistry. 275: 20717-25. PMID 10748172 DOI: 10.1074/jbc.M909895199  0.8
2000 Hulit J, Bash T, Fu M, Galbiati F, Albanese C, Sage DR, Schlegel A, Zhurinsky J, Shtutman M, Ben-Ze'ev A, Lisanti MP, Pestell RG. The cyclin D1 gene is transcriptionally repressed by caveolin-1. The Journal of Biological Chemistry. 275: 21203-9. PMID 10747899 DOI: 10.1074/jbc.M000321200  0.8
2000 Bregman DB, Pestell RG, Kidd VJ. Cell cycle regulation and RNA polymerase II Frontiers in Bioscience : a Journal and Virtual Library. 5. PMID 10704151  0.8
2000 Shambaugh GE, Haines GK, Koch A, Lee EJK, Zhou JN, Pestell R. Immunohistochemical examination of the INK4 and Cip inhibitors in the rat neonatal cerebellum: Cellular localization and the impact of protein calorie malnutrition Brain Research. 855: 11-22. PMID 10650125 DOI: 10.1016/S0006-8993(99)02028-4  0.8
2000 Lee RJ, Albanese C, Fu M, D'Amico M, Lin B, Watanabe G, Haines GK, Siegel PM, Hung MC, Yarden Y, Horowitz JM, Muller WJ, Pestell RG. Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway. Molecular and Cellular Biology. 20: 672-83. PMID 10611246 DOI: 10.1128/MCB.20.2.672-683.2000  0.8
1999 Albanese C, D'Amico M, Reutens AT, Fu M, Watanabe G, Lee RJ, Kitsis RN, Henglein B, Avantaggiati M, Somasundaram K, Thimmapaya B, Pestell RG. Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis Journal of Biological Chemistry. 274: 34186-34195. PMID 10567390 DOI: 10.1074/jbc.274.48.34186  0.8
1999 Schlegel A, Wang C, Katzenellenbogen BS, Pestell RG, Lisanti MP. Caveolin-1 potentiates estrogen receptor alpha (ERalpha) signaling. caveolin-1 drives ligand-independent nuclear translocation and activation of ERalpha. The Journal of Biological Chemistry. 274: 33551-6. PMID 10559241 DOI: 10.1074/jbc.274.47.33551  0.8
1999 Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity. The Journal of Biological Chemistry. 274: 32333-41. PMID 10542274 DOI: 10.1074/jbc.274.45.32333  0.8
1999 Carlson B, Lahusen T, Singh S, Loaiza-Perez A, Worland PJ, Pestell R, Albanese C, Sausville EA, Senderowicz AM. Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol Cancer Research. 59: 4634-4641. PMID 10493518  0.8
1999 Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C, Darnell JE. Stat3 as an oncogene. Cell. 98: 295-303. PMID 10458605 DOI: 10.1016/S0092-8674(00)81959-5  0.8
1999 Pestell RG, Albanese C, Reutens AT, Segall JE, Lee RJ, Arnold A. The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocrine Reviews. 20: 501-34. PMID 10453356 DOI: 10.1210/edrv.20.4.0373  0.8
1999 Pena P, Reutens AT, Albanese C, D'Amico M, Watanabe G, Donner A, Shu IW, Williams T, Pestell RG. Activator protein-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA. Molecular Endocrinology (Baltimore, Md.). 13: 1402-16. PMID 10446912 DOI: 10.1210/mend.13.8.0335  0.8
1999 Page K, Li J, Hodge JA, Liu PT, Vanden Hoek TL, Becker LB, Pestell RG, Rosner MR, Hershenson MB. Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells. The Journal of Biological Chemistry. 274: 22065-71. PMID 10419534 DOI: 10.1074/jbc.274.31.22065  0.8
1999 Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Molecular and Cellular Biology. 19: 5785-99. PMID 10409765 DOI: 10.1128/MCB.19.8.5785  0.8
1999 Ashton AW, Watanabe G, Albanese C, Harrington EO, Ware JA, Pestell RG. Protein kinase Cdelta inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27(Kip1). The Journal of Biological Chemistry. 274: 20805-11. PMID 10409620 DOI: 10.1074/jbc.274.30.20805  0.8
1999 Fan S, Wang JA, Yuan R, Ma Y, Meng Q, Erdos MR, Pestell RG, Yuan F, Auborn KJ, Goldberg ID, Rosen EM. BRCA1 inhibition of estrogen receptor signaling in transfected cells Science. 284: 1354-1356. PMID 10334989 DOI: 10.1126/science.284.5418.1354  0.8
1999 Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway Proceedings of the National Academy of Sciences of the United States of America. 96: 5522-5527. PMID 10318916 DOI: 10.1073/pnas.96.10.5522  0.8
1999 Lee RJ, Albanese C, Stenger RJ, Watanabe G, Inghirami G, Haines GK, Webster M, Muller WJ, Brugge JS, Davis RJ, Pestell RG. pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways: A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells Journal of Biological Chemistry. 274: 7341-7350. PMID 10066798 DOI: 10.1074/jbc.274.11.7341  0.8
1999 Beier F, Lee RJ, Taylor AC, Pestell RG, Luvalle P. Identification of the cyclin D1 gene as a target of activating transcription factor 2 in chondrocytes Proceedings of the National Academy of Sciences of the United States of America. 96: 1433-1438. PMID 9990041 DOI: 10.1073/pnas.96.4.1433  0.8
1999 Musa NL, Ramakrishnan M, Li J, Kartha S, Liu P, Pestell RG, Hershenson MB. Forskolin inhibits cyclin D1 expression in cultured airway smooth-muscle cells. American Journal of Respiratory Cell and Molecular Biology. 20: 352-8. PMID 9922228 DOI: 10.1165/ajrcmb.20.2.3160  0.8
1998 Engelman JA, Zhang X, Galbiati F, Volonte D, Sotgia F, Pestell RG, Minetti C, Scherer PE, Okamoto T, Lisanti MP. Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy. American Journal of Human Genetics. 63: 1578-87. PMID 9837809 DOI: 10.1086/302172  0.8
1998 Galbiati F, Volonte D, Engelman JA, Watanabe G, Burk R, Pestell RG, Lisanti MP. Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. The Embo Journal. 17: 6633-48. PMID 9822607 DOI: 10.1093/emboj/17.22.6633  0.8
1998 Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG, Greenberg ME. Fos family members induce cell cycle entry by activating cyclin D1. Molecular and Cellular Biology. 18: 5609-19. PMID 9710644  0.8
1998 Watanabe G, Pena P, Shambaugh GE, Haines GK, Pestell RG. Regulation of cyclin dependent kinase inhibitor proteins during neonatal cerebella development Developmental Brain Research. 108: 77-87. PMID 9693786 DOI: 10.1016/S0165-3806(98)00032-7  0.8
1998 Engelman JA, Lee RJ, Karnezis A, Bearss DJ, Webster M, Siegel P, Muller WJ, Windle JJ, Pestell RG, Lisanti MP. Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer. The Journal of Biological Chemistry. 273: 20448-55. PMID 9685399 DOI: 10.1074/jbc.273.32.20448  0.8
1998 Westwick JK, Lee RJ, Lambert QT, Symons M, Pestell RG, Der CJ, Whitehead IP. Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun Journal of Biological Chemistry. 273: 16739-16747. PMID 9642229 DOI: 10.1074/jbc.273.27.16739  0.8
1998 Ramakrishnan M, Musa NL, Li J, Liu PT, Pestell RG, Hershenson MB. Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in primary tracheal myocytes. American Journal of Respiratory Cell and Molecular Biology. 18: 736-40. PMID 9618377 DOI: 10.1165/ajrcmb.18.6.3152  0.8
1998 Watanabe G, Albanese C, Lee RJ, Reutens A, Vairo G, Henglein B, Pestell RG. Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1 Molecular and Cellular Biology. 18: 3212-3222. PMID 9584162  0.8
1998 Akama KT, Albanese C, Pestell RG, Van Eldik LJ. Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 95: 5795-800. PMID 9576964 DOI: 10.1073/pnas.95.10.5795  0.8
1997 Li X, Hales KH, Watanabe G, Lee RJ, Pestell RG, Hales DB. The effect of tumor necrosis factor-alpha and cAMP on induction of AP-1 activity in MA-10 tumor Leydig cells. Endocrine. 6: 317-24. PMID 9368689 DOI: 10.1007/BF02820509  0.8
1997 Xiong W, Pestell R, Rosner MR. Role of cyclins in neuronal differentiation of immortalized hippocampal cells Molecular and Cellular Biology. 17: 6585-6597. PMID 9343422 DOI: 10.1128/MCB.17.11.6585  0.8
1997 Thurston VC, Pena P, Pestell R, Binder LI. Nucleolar localization of the microtubule-associated protein tau in neuroblastomas using sense and anti-sense transfection strategies Cell Motility and the Cytoskeleton. 38: 100-110. PMID 9295144 DOI: 10.1002/(SICI)1097-0169(1997)38:1<100::AID-CM9>3.0.CO;2-C  0.8
1997 Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J, Pestell RG, Hinds PW, Dowdy SF, Brown M, Ewen ME. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Molecular and Cellular Biology. 17: 5338-47. PMID 9271411 DOI: 10.1128/MCB.17.9.5338  0.8
1997 Watanabe G, Pena P, Albanese C, Wilsbacher LD, Young JB, Pestell RG. Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo. The Journal of Biological Chemistry. 272: 20063-9. PMID 9242678 DOI: 10.1074/jbc.272.32.20063  0.8
1997 Xiong W, Pestell RG, Watanabe G, Li J, Rosner MR, Hershenson MB. Cyclin D1 is required for S phase traversal in bovine tracheal myocytes. The American Journal of Physiology. 272: L1205-10. PMID 9227524  0.8
1997 Johnson W, Albanese C, Handwerger S, Williams T, Pestell RG, Jameson JL. Regulation of the human chorionic gonadotropin α- and β-subunit promoters by AP-2 Journal of Biological Chemistry. 272: 15405-15412. PMID 9182571 DOI: 10.1074/jbc.272.24.15405  0.8
1997 Westwick JK, Lambert QT, Clark GJ, Symons M, Van Aelst L, Pestell RG, Der CJ. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Molecular and Cellular Biology. 17: 1324-35. PMID 9032259  0.8
1997 Pestell RG, Albanese C, Watanabe G, Lee RJ, Lastowiecki P, Zon L, Ostrowski M, Jameson JL. Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways. Molecular Endocrinology (Baltimore, Md.). 10: 1084-94. PMID 8885243 DOI: 10.1210/mend.10.9.8885243  0.44
1996 Watanabe G, Howe A, Lee RJ, Albanese C, Shu IW, Karnezis AN, Zon L, Kyriakis J, Rundell K, Pestell RG. Induction of cyclin D1 by simian virus 40 small tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 93: 12861-6. PMID 8917510 DOI: 10.1073/pnas.93.23.12861  0.8
1996 Shambaugh GE, Lee RJ, Watanabe G, Erfurth F, Karnezis AN, Koch AE, Haines GK, Halloran M, Brody BA, Pestell RG. Reduced cyclin D1 expression in the cerebella of nutritionally deprived rats correlates with developmental delay and decreased cellular DNA synthesis. Journal of Neuropathology and Experimental Neurology. 55: 1009-20. PMID 8800097 DOI: 10.1097/00005072-199609000-00008  0.68
1996 Watanabe G, Lee RJ, Albanese C, Rainey WE, Batlle D, Pestell RG. Angiotensin II activation of cyclin D1-dependent kinase activity Journal of Biological Chemistry. 271: 22570-22577. PMID 8798425 DOI: 10.1074/jbc.271.37.22570  0.8
1996 Sundaresan S, Colin IM, Pestell RG, Jameson JL. Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C. Endocrinology. 137: 304-11. PMID 8536629 DOI: 10.1210/endo.137.1.8536629  0.8
1995 Pestell RG, Albanese C, Watanabe G, Johnson J, Eklund N, Lastowiecki P, Jameson JL. Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter Journal of Biological Chemistry. 270: 18301-18308. PMID 7629150 DOI: 10.1074/jbc.270.31.18301  0.8
1995 Albanese C, Johnson J, Watanabe G, Eklund N, Vu D, Arnold A, Pestell RG. Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions Journal of Biological Chemistry. 270: 23589-23597. PMID 7559524  0.8
1994 Pestell RG, Hollenberg AN, Albanese C, Jameson JL. c-Jun represses transcription of the human chorionic gonadotropin α and β genes through distinct types of CREs Journal of Biological Chemistry. 269: 31090-31096. PMID 7983049  0.8
1994 Hollenberg AN, Pestell RG, Albanese C, Boers ME, Jameson JL. Multiple promoter elements in the human chorionic gonadotropin β subunit genes distinguish their expression from the luteinizing hormone β gene Molecular and Cellular Endocrinology. 106: 111-119. PMID 7534731 DOI: 10.1016/0303-7207(94)90192-9  0.8
1993 Pestell RG, Ward GM, Galvin P, Best JD, Alford FP. Impaired glucose tolerance after endurance exercise is associated with reduced insulin secretion rather than altered insulin sensitivity Metabolism. 42: 277-282. PMID 8487644 DOI: 10.1016/0026-0495(93)90074-X  0.8
1993 Pestell RG, Hammond VE, Crawford RJ. Molecular cloning and characterization of the cyclic AMP-responsive ovine CYP11A1 (cholesterol side-chain cleavage) gene promoter: DNase 1 protection of conserved consensus elements Journal of Molecular Endocrinology. 10: 297-311. PMID 8373514  0.8
1992 Galvin P, Ward G, Walters J, Pestell R, Koschmann M, Vaag A, Martin I, Best JD, Alford F. A simple method for quantitation of insulin sensitivity and insulin release from an intravenous glucose tolerance test Diabetic Medicine. 9: 921-928. PMID 1478037  0.8
1991 Pestell RG, Kirsner RLG, Best JD. Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus Diabetes. 40: 867-872. PMID 2060722  0.8
1991 Pestell R, Herington A, Best J, Boolell M, McKelvie P, Arnott R, Alford F. Growth hormone excess and galactorrhoea without acromegalic features. Case reports. British Journal of Obstetrics and Gynaecology. 98: 92-7. PMID 1998639  0.8
1991 Pestell R, Ball JRB. Authoritarianism among medicine and law students Australian and New Zealand Journal of Psychiatry. 25: 265-269. PMID 1877963 DOI: 10.3109/00048679109077744  0.8
1991 Page R, Boolell M, Kalfas A, Sawyer S, Pestell R, Ward G, Alford F. Insulin secretion, insulin sensitivity and glucose-mediated glucose disposal in Cushing's disease: A minimal model analysis Clinical Endocrinology. 35: 509-517. PMID 1769133  0.8
1990 Chamberlain KG, Pestell RG, Best JD. Platelet catecholamine contents are cumulative indexes of sympathoadrenal activity American Journal of Physiology - Endocrinology and Metabolism. 259. PMID 2382708  0.8
1990 Best JD, Alford FP, Martin IK, Pestell RG, Ward GM. Practical application of methods for in vivo assessment of insulin secretion and action Hormone and Metabolic Research. 24: 60-66. PMID 2272628  0.8
1990 Pestell R, Alford F, Ramos R, Sawyer S, Best J, Ward G. Insulin secretion, insulin sensitivity and glucose-mediated glucose disposal in thyrotoxicosis: A minimal model analysis Clinical Endocrinology. 33: 481-493. PMID 2225490  0.8
1990 Arnott RD, Pestell RG, McKelvie PA, Henderson JK, McNeill PM, Alford FP. A critical evaluation of transsphenoidal pituitary surgery in the treatment of Cushing's disease: prediction of outcome. Acta Endocrinologica. 123: 423-30. PMID 2173325  0.8
1990 Pestell RG, Best JD, Alford FP. Lymphocytic hypophysitis. The clinical spectrum of the disorder and evidence for an autoimmune pathogenesis Clinical Endocrinology. 33: 457-466. PMID 2121396  0.8
1989 Pestell RG, Alford FP, Best JD. Familial acromegaly Acta Endocrinologica. 121: 286-289. PMID 2773624  0.8
1989 Pestell RG, Hurley DM, Vandongen R. Biochemical and hormonal changes during a 1000 km ultramarathon Clinical and Experimental Pharmacology and Physiology. 16: 353-361. PMID 2548778  0.8
1989 Pestell RG, Crock PA, Ward GM, Alford FP, Best JD. Fenfluramine increases insulin action in patients with NIDDM Diabetes Care. 12: 252-258. PMID 2495916  0.8
1989 Pestell RG, Taylor RR. Effect of cigarette smoking on the frequency of ventricular premature complexes in normal subjects Clinical and Experimental Pharmacology and Physiology. 16: 647-650. PMID 2477179  0.8
1988 Crock PA, Pestell RG, Calenti AJ, Gilford EJ, Henderson JK, Best JD, Alford FP. Multiple pituitary hormone gradients from inferior petrosal sinus sampling in Cushing's disease Acta Endocrinologica. 119: 75-80. PMID 2842995  0.8
1987 Pestell RG, Barr AL, Brand G. Vitamin C and congestive cardiac failure Medical Journal of Australia. 147: 153-154. PMID 3600482  0.8
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