Richard Pestell - Publications

Biochemistry and Molecular Biology Thomas Jefferson University 
Molecular Biology, Biochemistry, Cell Biology, Oncology

265 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Jiao X, Li Z, Wang M, Katiyar S, Di Sante G, Farshchian M, South AP, Cocola C, Colombo D, Reinbold R, Zucchi I, Wu K, Tabas I, Spike BT, Pestell RG. Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool. Stem Cell Reports. PMID 30554919 DOI: 10.1016/j.stemcr.2018.11.010  0.36
2018 Xu H, Bai X, Yu S, Liu Q, Pestell RG, Wu K. MAT1 correlates with molecular subtypes and predicts poor survival in breast cancer. Chinese Journal of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu. 30: 351-363. PMID 30046229 DOI: 10.21147/j.issn.1000-9604.2018.03.07  0.36
2018 Liu Q, Li A, Yu S, Qin S, Han N, Pestell RG, Han X, Wu K. DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis. Journal of Hematology & Oncology. 11: 53. PMID 29636079 DOI: 10.1186/s13045-018-0597-1  0.36
2017 Pestell TG, Jiao X, Kumar M, Peck AR, Prisco M, Deng S, Li Z, Ertel A, Casimiro MC, Ju X, Di Rocco A, Di Sante G, Katiyar S, Shupp A, Lisanti MP, ... ... Pestell RG, et al. Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth. Oncotarget. 8: 81754-81775. PMID 29137220 DOI: 10.18632/oncotarget.19953  0.36
2017 Yu S, Li A, Liu Q, Yuan X, Xu H, Jiao D, Pestell RG, Han X, Wu K. Recent advances of bispecific antibodies in solid tumors. Journal of Hematology & Oncology. 10: 155. PMID 28931402 DOI: 10.1186/s13045-017-0522-z  0.36
2017 Xu H, Yu S, Yuan X, Xiong J, Kuang D, Pestell RG, Wu K. DACH1 suppresses breast cancer as a negative regulator of CD44. Scientific Reports. 7: 4361. PMID 28659634 DOI: 10.1038/s41598-017-04709-2  0.36
2017 Casimiro MC, Di Sante G, Di Rocco A, Loro E, Pupo C, Pestell T, Bisetto S, Velasco-Velàzquez MA, Jiao X, Li Z, Kusminski CM, Seifert EL, Wang C, Ly D, Zheng B, ... ... Pestell RG, et al. Cyclin D1 restrains oncogene-induced autophagy by regulating the AMPK-LKB1 signaling axis. Cancer Research. PMID 28522753 DOI: 10.1158/0008-5472.CAN-16-0425  0.36
2017 Xu H, Yu S, Liu Q, Yuan X, Mani S, Pestell RG, Wu K. Recent advances of highly selective CDK4/6 inhibitors in breast cancer. Journal of Hematology & Oncology. 10: 97. PMID 28438180 DOI: 10.1186/s13045-017-0467-2  0.36
2016 Kong D, Liu Y, Liu Q, Han N, Zhang C, Pestell RG, Wu K, Wu G. The retinal determination gene network: from developmental regulator to cancer therapeutic target. Oncotarget. PMID 27203207 DOI: 10.18632/oncotarget.9394  0.36
2016 Di Sante G, Casimiro MC, Pestell TG, Pestell RG. Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy. Journal of Visualized Experiments : Jove. PMID 27168174 DOI: 10.3791/53657  0.36
2015 Xu H, Tian Y, Yuan X, Wu H, Liu Q, Pestell RG, Wu K. The role of CD44 in epithelial-mesenchymal transition and cancer development. Oncotargets and Therapy. 8: 3783-92. PMID 26719706 DOI: 10.2147/OTT.S95470  0.36
2015 Wu K, Yuan X, Pestell R. Endogenous Dach1 in cancer. Oncoscience. 2: 803-4. PMID 26682253 DOI: 10.18632/oncoscience.251  0.36
2015 Casimiro MC, Di Sante G, Ju X, Li Z, Chen K, Crosariol M, Yaman I, Gormley M, Meng H, Lisanti MP, Pestell RG. Cyclin D1 promotes androgen-dependent DNA damage repair in prostate cancer cells. Cancer Research. PMID 26582866 DOI: 10.1158/0008-5472.CAN-15-0999  0.36
2015 Pestell RG, Fatatis A, Jiao X. Mitochondrial mass and DNA repair in breast cancer stem cells. Oncotarget. PMID 26564961 DOI: 10.18632/oncotarget.6305  0.36
2015 Zhang J, Wang C, Chen X, Takada M, Fan C, Zheng X, Wen H, Liu Y, Wang C, Pestell RG, Aird KM, Kaelin WG, Liu XS, Zhang Q. EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer. The Embo Journal. PMID 26492917 DOI: 10.15252/embj.201591437  0.36
2015 Casimiro MC, Arnold A, Pestell RG. Kinase independent oncogenic cyclin D1. Aging. 7: 455-6. PMID 26187783  0.36
2015 Trerotola M, Ganguly KK, Fazli L, Fedele C, Lu H, Dutta A, Liu Q, De Angelis T, Riddell LW, Riobo NA, Gleave ME, Zoubeidi A, Pestell RG, Altieri DC, Languino LR. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts. Oncotarget. 6: 14318-28. PMID 26015409  0.36
2015 Casimiro MC, Di Sante G, Crosariol M, Loro E, Dampier W, Ertel A, Yu Z, Saria EA, Papanikolaou A, Li Z, Wang C, Addya S, Lisanti MP, Fortina P, Cardiff RD, ... ... Pestell RG, et al. Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis. Oncotarget. 6: 8525-38. PMID 25940700  0.36
2015 Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, Di Sante G, Xu S, Wang Q, Li K, Sun X, Xu C, Li Z, Casimiro MC, Ertel A, ... ... Pestell RG, et al. The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module. Cancer Research. 75: 1992-2004. PMID 25769723 DOI: 10.1158/0008-5472.CAN-14-0611  0.36
2015 Pestell RG, Rizvanov AA. Antibiotics for cancer therapy. Oncotarget. 6: 2587-8. PMID 25739117 DOI: 10.18632/oncotarget.3388  0.36
2015 Lamb R, Harrison H, Smith DL, Townsend PA, Jackson T, Ozsvari B, Martinez-Outschoorn UE, Pestell RG, Howell A, Lisanti MP, Sotgia F. Targeting tumor-initiating cells: eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction. Oncotarget. 6: 4585-601. PMID 25671304  0.36
2015 Di Sante G, Wang L, Wang C, Jiao X, Casimiro MC, Chen K, Pestell TG, Yaman I, Di Rocco A, Sun X, Horio Y, Powell MJ, He X, McBurney MW, Pestell RG. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration. Molecular Endocrinology (Baltimore, Md.). 29: 200-12. PMID 25545407 DOI: 10.1210/me.2014-1228  0.36
2015 Di Sante G, Pestell TG, Casimiro MC, Bisetto S, Powell MJ, Lisanti MP, Cordon-Cardo C, Castillo-Martin M, Bonal DM, Debattisti V, Chen K, Wang L, He X, McBurney MW, Pestell RG. Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria. The American Journal of Pathology. 185: 266-79. PMID 25529796 DOI: 10.1016/j.ajpath.2014.09.014  0.36
2015 Cekanova M, Fernando RI, Siriwardhana N, Sukhthankar M, De la Parra C, Woraratphoka J, Malone C, Ström A, Baek SJ, Wade PA, Saxton AM, Donnell RM, Pestell RG, Dharmawardhane S, Wimalasena J. BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion. Experimental Cell Research. 331: 1-10. PMID 25499972 DOI: 10.1016/j.yexcr.2014.11.016  0.36
2015 Wang C, Zhang X, Tian L, Pestell RG. Emerging roles of peroxisome proliferator-activated receptor gamma in cancer Molecular Oncology: Causes of Cancer and Targets For Treatment. 392-402. DOI: 10.1017/CBO9781139046947.034  0.36
2014 Sicoli D, Jiao X, Ju X, Velasco-Velazquez M, Ertel A, Addya S, Li Z, Andò S, Fatatis A, Paudyal B, Cristofanilli M, Thakur ML, Lisanti MP, Pestell RG. CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines. Cancer Research. 74: 7103-14. PMID 25452256 DOI: 10.1158/0008-5472.CAN-14-0612  0.36
2014 Ringer L, Sirajuddin P, Tricoli L, Waye S, Choudhry MU, Parasido E, Sivakumar A, Heckler M, Naeem A, Abdelgawad I, Liu X, Feldman AS, Lee RJ, Wu CL, Yenugonda V, ... ... Pestell RG, et al. The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells. Oncotarget. 5: 10678-91. PMID 25296977  0.36
2014 Velasco-Velázquez M, Xolalpa W, Pestell RG. The potential to target CCL5/CCR5 in breast cancer. Expert Opinion On Therapeutic Targets. 18: 1265-75. PMID 25256399 DOI: 10.1517/14728222.2014.949238  0.36
2014 Tian L, Wang C, Hagen FK, Gormley M, Addya S, Soccio R, Casimiro MC, Zhou J, Powell MJ, Xu P, Deng H, Sauve AA, Pestell RG. Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells. Oncotarget. 5: 7303-15. PMID 25229978  0.36
2014 Jin L, Lim M, Zhao S, Sano Y, Simone BA, Savage JE, Wickstrom E, Camphausen K, Pestell RG, Simone NL. The metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 cluster. Breast Cancer Research and Treatment. 146: 41-50. PMID 24863696 DOI: 10.1007/s10549-014-2978-7  0.36
2014 Li Z, Chen K, Jiao X, Wang C, Willmarth NE, Casimiro MC, Li W, Ju X, Kim SH, Lisanti MP, Katzenellenbogen JA, Pestell RG. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling. Cancer Research. 74: 3959-70. PMID 24830723 DOI: 10.1158/0008-5472.CAN-13-3137  0.36
2014 Yu Z, Xu Z, Disante G, Wright J, Wang M, Li Y, Zhao Q, Ren T, Ju X, Gutman E, Wang G, Addya S, Li T, Xiang Z, Wang C, ... ... Pestell R, et al. miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget. 5: 1083-90. PMID 24658544  0.36
2014 Mercier I, Gonzales DM, Quann K, Pestell TG, Molchansky A, Sotgia F, Hulit J, Gandara R, Wang C, Pestell RG, Lisanti MP, Jasmin JF. CAPER, a novel regulator of human breast cancer progression. Cell Cycle (Georgetown, Tex.). 13: 1256-64. PMID 24621503 DOI: 10.4161/cc.28156  0.36
2014 Pestell RG, Yu Z. Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo. Asian Journal of Andrology. 16: 268-9. PMID 24435053 DOI: 10.4103/1008-682X.122364  0.36
2014 Casimiro MC, Velasco-Velázquez M, Aguirre-Alvarado C, Pestell RG. Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present. Expert Opinion On Investigational Drugs. 23: 295-304. PMID 24387133 DOI: 10.1517/13543784.2014.867017  0.36
2014 Wu K, Chen K, Wang C, Jiao X, Wang L, Zhou J, Wang J, Li Z, Addya S, Sorensen PH, Lisanti MP, Quong A, Ertel A, Pestell RG. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Research. 74: 829-39. PMID 24335958 DOI: 10.1158/0008-5472.CAN-13-2466  0.36
2014 Ju X, Casimiro MC, Gormley M, Meng H, Jiao X, Katiyar S, Crosariol M, Chen K, Wang M, Quong AA, Lisanti MP, Ertel A, Pestell RG. Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint. Cancer Research. 74: 508-19. PMID 24282282 DOI: 10.1158/0008-5472.CAN-13-1313  0.36
2014 Merchand-Reyes G, Pelayo R, Pavón L, Pestell RG, Velasco-Velázquez M. Role of Cancer Stem Cells in Metastasis Cancer Stem Cells. 259-271. DOI: 10.1002/9781118356203.ch20  0.36
2013 Yu Z, Wang L, Wang C, Ju X, Wang M, Chen K, Loro E, Li Z, Zhang Y, Wu K, Casimiro MC, Gormley M, Ertel A, Fortina P, Chen Y, ... ... Pestell RG, et al. Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. Nature Communications. 4: 2812. PMID 24287487 DOI: 10.1038/ncomms3812  0.36
2013 Lisanti MP, Sotgia F, Pestell RG, Howell A, Martinez-Outschoorn UE. Stromal glycolysis and MCT4 are hallmarks of DCIS progression to invasive breast cancer. Cell Cycle (Georgetown, Tex.). 12: 2935-6. PMID 23989616 DOI: 10.4161/cc.26280  0.36
2013 Martinez-Outschoorn UE, Whitaker-Menezes D, Valsecchi M, Martinez-Cantarin MP, Dulau-Florea A, Gong J, Howell A, Flomenberg N, Pestell RG, Wagner J, Arana-Yi C, Sharma M, Sotgia F, Lisanti MP. Reverse Warburg effect in a patient with aggressive B-cell lymphoma: is lactic acidosis a paraneoplastic syndrome? Seminars in Oncology. 40: 403-18. PMID 23972703 DOI: 10.1053/j.seminoncol.2013.04.016  0.36
2013 Casimiro MC, Wang C, Li Z, Di Sante G, Willmart NE, Addya S, Chen L, Liu Y, Lisanti MP, Pestell RG. Cyclin D1 determines estrogen signaling in the mammary gland in vivo. Molecular Endocrinology (Baltimore, Md.). 27: 1415-28. PMID 23864650 DOI: 10.1210/me.2013-1065  0.36
2013 Martinez-Outschoorn UE, Curry JM, Ko YH, Lin Z, Tuluc M, Cognetti D, Birbe RC, Pribitkin E, Bombonati A, Pestell RG, Howell A, Sotgia F, Lisanti MP. Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4. Cell Cycle (Georgetown, Tex.). 12: 2580-97. PMID 23860378 DOI: 10.4161/cc.25510  0.36
2013 Chen K, Wu K, Gormley M, Ertel A, Wang J, Zhang W, Zhou J, Disante G, Li Z, Rui H, Quong AA, McMahon SB, Deng H, Lisanti MP, Wang C, ... Pestell RG, et al. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. Oncotarget. 4: 923-35. PMID 23798621  0.36
2013 Pestell RG. New roles of cyclin D1. The American Journal of Pathology. 183: 3-9. PMID 23790801 DOI: 10.1016/j.ajpath.2013.03.001  0.36
2013 Velasco-Velázquez M, Pestell RG. The CCL5/CCR5 axis promotes metastasis in basal breast cancer. Oncoimmunology. 2: e23660. PMID 23734321 DOI: 10.4161/onci.23660  0.36
2013 Saleh AD, Simone BA, Palazzo J, Savage JE, Sano Y, Dan T, Jin L, Champ CE, Zhao S, Lim M, Sotgia F, Camphausen K, Pestell RG, Mitchell JB, Lisanti MP, et al. Caloric restriction augments radiation efficacy in breast cancer. Cell Cycle (Georgetown, Tex.). 12: 1955-63. PMID 23708519 DOI: 10.4161/cc.25016  0.36
2013 Wu K, Li Z, Cai S, Tian L, Chen K, Wang J, Hu J, Sun Y, Li X, Ertel A, Pestell RG. EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1. Cancer Research. 73: 4488-99. PMID 23636126 DOI: 10.1158/0008-5472.CAN-12-4078  0.36
2013 Shen D, Bai M, Tang R, Xu B, Ju X, Pestell RG, Achilefu S. Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity. Scientific Reports. 3: 1697. PMID 23603888 DOI: 10.1038/srep01697  0.36
2013 Quann K, Gonzales DM, Mercier I, Wang C, Sotgia F, Pestell RG, Lisanti MP, Jasmin JF. Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide Cell Cycle. 12: 1510-1520. PMID 23598719 DOI: 10.4161/cc.24497  0.36
2013 Avena P, Anselmo W, Whitaker-Menezes D, Wang C, Pestell RG, Lamb RS, Hulit J, Casaburi I, Andò S, Martinez-Outschoorn UE, Lisanti MP, Sotgia F. Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle (Georgetown, Tex.). 12: 1360-70. PMID 23574724 DOI: 10.4161/cc.24289  0.36
2013 Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, ... ... Pestell RG, et al. Dachshund binds p53 to block the growth of lung adenocarcinoma cells. Cancer Research. 73: 3262-74. PMID 23492369 DOI: 10.1158/0008-5472.CAN-12-3191  0.36
2013 Champ CE, Baserga R, Mishra MV, Jin L, Sotgia F, Lisanti MP, Pestell RG, Dicker AP, Simone NL. Nutrient restriction and radiation therapy for cancer treatment: when less is more. The Oncologist. 18: 97-103. PMID 23299773 DOI: 10.1634/theoncologist.2012-0164  0.36
2013 Trimmer C, Bonuccelli G, Katiyar S, Sotgia F, Pestell RG, Lisanti MP, Capozza F. Cav1 suppresses tumor growth and metastasis in a murine model of cutaneous SCC through modulation of MAPK/AP-1 activation. The American Journal of Pathology. 182: 992-1004. PMID 23267770 DOI: 10.1016/j.ajpath.2012.11.008  0.36
2013 Schild R, Knüppel T, Konrad M, Bergmann C, Trautmann A, Kemper MJ, Wu K, Yaklichkin S, Wang J, Pestell R, Müller-Wiefel DE, Schaefer F, Weber S. Double homozygous missense mutations in DACH1 and BMP4 in a patient with bilateral cystic renal dysplasia. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 28: 227-32. PMID 23262432 DOI: 10.1093/ndt/gfs539  0.36
2013 Ju X, Ertel A, Casimiro MC, Yu Z, Meng H, McCue PA, Walters R, Fortina P, Lisanti MP, Pestell RG. Novel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures. Cancer Research. 73: 978-89. PMID 23204233 DOI: 10.1158/0008-5472.CAN-12-2133  0.36
2013 Yu Z, Tozeren A, Pestell RG. Function of miRNAs in tumor cell proliferation Microrna in Cancer. 2147483647: 13-27. DOI: 10.1007/978-94-007-4655-8_2  0.36
2013 Wang C, Pestell TG, Pestell RG. A new perspective on cyclin D1: Beyond cell cycle regulation Cell and Molecular Biology of Breast Cancer. 289-304. DOI: 10.1007/978-1-62703-634-4_13  0.36
2012 Casimiro MC, Crosariol M, Loro E, Li Z, Pestell RG. Cyclins and cell cycle control in cancer and disease. Genes & Cancer. 3: 649-57. PMID 23634253 DOI: 10.1177/1947601913479022  0.36
2012 Yu Z, Li Y, Fan H, Liu Z, Pestell RG. miRNAs regulate stem cell self-renewal and differentiation. Frontiers in Genetics. 3: 191. PMID 23056008 DOI: 10.3389/fgene.2012.00191  0.36
2012 Yu Z, Pestell TG, Lisanti MP, Pestell RG. Cancer stem cells. The International Journal of Biochemistry & Cell Biology. 44: 2144-51. PMID 22981632 DOI: 10.1016/j.biocel.2012.08.022  0.36
2012 Capparelli C, Chiavarina B, Whitaker-Menezes D, Pestell TG, Pestell RG, Hulit J, Andò S, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis. Cell Cycle (Georgetown, Tex.). 11: 3599-610. PMID 22935696 DOI: 10.4161/cc.21884  0.36
2012 Carito V, Bonuccelli G, Martinez-Outschoorn UE, Whitaker-Menezes D, Caroleo MC, Cione E, Howell A, Pestell RG, Lisanti MP, Sotgia F. Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth. Cell Cycle (Georgetown, Tex.). 11: 3403-14. PMID 22918248 DOI: 10.4161/cc.21701  0.36
2012 Chiavarina B, Martinez-Outschoorn UE, Whitaker-Menezes D, Howell A, Tanowitz HB, Pestell RG, Sotgia F, Lisanti MP. Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells. Cell Cycle (Georgetown, Tex.). 11: 3280-9. PMID 22894905 DOI: 10.4161/cc.21643  0.36
2012 Guido C, Whitaker-Menezes D, Lin Z, Pestell RG, Howell A, Zimmers TA, Casimiro MC, Aquila S, Ando' S, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth. Oncotarget. 3: 798-810. PMID 22878233 DOI: 10.18632/oncotarget.574  0.36
2012 Guido C, Whitaker-Menezes D, Capparelli C, Balliet R, Lin Z, Pestell RG, Howell A, Aquila S, Andò S, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production. Cell Cycle (Georgetown, Tex.). 11: 3019-35. PMID 22874531 DOI: 10.4161/cc.21384  0.36
2012 Salem AF, Whitaker-Menezes D, Lin Z, Martinez-Outschoorn UE, Tanowitz HB, Al-Zoubi MS, Howell A, Pestell RG, Sotgia F, Lisanti MP. Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells. Cell Cycle (Georgetown, Tex.). 11: 2545-56. PMID 22722266 DOI: 10.4161/cc.20920  0.36
2012 Mercier I, Camacho J, Titchen K, Gonzales DM, Quann K, Bryant KG, Molchansky A, Milliman JN, Whitaker-Menezes D, Sotgia F, Jasmin JF, Schwarting R, Pestell RG, Blagosklonny MV, Lisanti MP. Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug. The American Journal of Pathology. 181: 278-93. PMID 22698676 DOI: 10.1016/j.ajpath.2012.03.017  0.36
2012 Capparelli C, Whitaker-Menezes D, Guido C, Balliet R, Pestell TG, Howell A, Sneddon S, Pestell RG, Martinez-Outschoorn U, Lisanti MP, Sotgia F. CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth. Cell Cycle (Georgetown, Tex.). 11: 2272-84. PMID 22684333 DOI: 10.4161/cc.20717  0.36
2012 Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle (Georgetown, Tex.). 11: 2285-302. PMID 22684298 DOI: 10.4161/cc.20718  0.36
2012 Velasco-Velázquez M, Jiao X, De La Fuente M, Pestell TG, Ertel A, Lisanti MP, Pestell RG. CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Research. 72: 3839-50. PMID 22637726 DOI: 10.1158/0008-5472.CAN-11-3917  0.36
2012 Casimiro MC, Pestell RG. Cyclin d1 induces chromosomal instability. Oncotarget. 3: 224-5. PMID 22538871 DOI: 10.18632/oncotarget.476  0.36
2012 Clark PM, Dawany N, Dampier W, Byers SW, Pestell RG, Tozeren A. Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases. Inflammatory Bowel Diseases. 18: 2315-33. PMID 22488912 DOI: 10.1002/ibd.22958  0.36
2012 Capozza F, Trimmer C, Castello-Cros R, Katiyar S, Whitaker-Menezes D, Follenzi A, Crosariol M, Llaverias G, Sotgia F, Pestell RG, Lisanti MP. Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration. Cancer Research. 72: 2262-74. PMID 22396494 DOI: 10.1158/0008-5472.CAN-11-2593  0.36
2012 Sotgia F, Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Philp NJ, Pestell RG, Lisanti MP. Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue. Cell Cycle (Georgetown, Tex.). 11: 1445-54. PMID 22395432 DOI: 10.4161/cc.19841  0.36
2012 Yu Z, Pestell RG. Small non-coding RNAs govern mammary gland tumorigenesis. Journal of Mammary Gland Biology and Neoplasia. 17: 59-64. PMID 22382486 DOI: 10.1007/s10911-012-9246-4  0.36
2012 Casimiro MC, Crosariol M, Loro E, Ertel A, Yu Z, Dampier W, Saria EA, Papanikolaou A, Stanek TJ, Li Z, Wang C, Fortina P, Addya S, Tozeren A, Knudsen ES, ... ... Pestell RG, et al. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice. The Journal of Clinical Investigation. 122: 833-43. PMID 22307325 DOI: 10.1172/JCI60256  0.36
2012 Velasco-Velázquez MA, Homsi N, De La Fuente M, Pestell RG. Breast cancer stem cells. The International Journal of Biochemistry & Cell Biology. 44: 573-7. PMID 22249027 DOI: 10.1016/j.biocel.2011.12.020  0.36
2012 Ertel A, Tsirigos A, Whitaker-Menezes D, Birbe RC, Pavlides S, Martinez-Outschoorn UE, Pestell RG, Howell A, Sotgia F, Lisanti MP. Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism. Cell Cycle (Georgetown, Tex.). 11: 253-63. PMID 22234241 DOI: 10.4161/cc.11.2.19006  0.36
2012 Katiyar S, Jiao X, Addya S, Ertel A, Covarrubias Y, Rose V, Casimiro MC, Zhou J, Lisanti MP, Nasim T, Fortina P, Pestell RG. Mammary gland selective excision of c-jun identifies its role in mRNA splicing. Cancer Research. 72: 1023-34. PMID 22174367 DOI: 10.1158/0008-5472.CAN-11-3647  0.36
2012 Sotgia F, Martinez-Outschoorn UE, Howell A, Pestell RG, Pavlides S, Lisanti MP. Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms. Annual Review of Pathology. 7: 423-67. PMID 22077552 DOI: 10.1146/annurev-pathol-011811-120856  0.36
2012 Pavlides S, Vera I, Gandara R, Sneddon S, Pestell RG, Mercier I, Martinez-Outschoorn UE, Whitaker-Menezes D, Howell A, Sotgia F, Lisanti MP. Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis. Antioxidants & Redox Signaling. 16: 1264-84. PMID 21883043 DOI: 10.1089/ars.2011.4243  0.36
2011 Ko YH, Lin Z, Flomenberg N, Pestell RG, Howell A, Sotgia F, Lisanti MP, Martinez-Outschoorn UE. Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance. Cancer Biology & Therapy. 12: 1085-97. PMID 22236876 DOI: 10.4161/cbt.12.12.18671  0.36
2011 Chiavarina B, Whitaker-Menezes D, Martinez-Outschoorn UE, Witkiewicz AK, Birbe R, Howell A, Pestell RG, Smith J, Daniel R, Sotgia F, Lisanti MP. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth. Cancer Biology & Therapy. 12: 1101-13. PMID 22236875 DOI: 10.4161/cbt.12.12.18703  0.36
2011 Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. Cell Cycle (Georgetown, Tex.). 10: 4047-64. PMID 22134189 DOI: 10.4161/cc.10.23.18151  0.36
2011 Montie HL, Pestell RG, Merry DE. SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17425-36. PMID 22131404 DOI: 10.1523/JNEUROSCI.3958-11.2011  0.36
2011 Balliet RM, Capparelli C, Guido C, Pestell TG, Martinez-Outschoorn UE, Lin Z, Whitaker-Menezes D, Chiavarina B, Pestell RG, Howell A, Sotgia F, Lisanti MP. Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection. Cell Cycle (Georgetown, Tex.). 10: 4065-73. PMID 22129993 DOI: 10.4161/cc.10.23.18254  0.36
2011 Martinez-Outschoorn UE, Goldberg A, Lin Z, Ko YH, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP. Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells. Cancer Biology & Therapy. 12: 924-38. PMID 22041887 DOI: 10.4161/cbt.12.10.17780  0.36
2011 Salem AF, Bonuccelli G, Bevilacqua G, Arafat H, Pestell RG, Sotgia F, Lisanti MP. Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition. Cell Cycle (Georgetown, Tex.). 10: 3692-700. PMID 22041584 DOI: 10.4161/cc.10.21.17895  0.36
2011 Martinez-Outschoorn UE, Pestell RG, Howell A, Tykocinski ML, Nagajyothi F, Machado FS, Tanowitz HB, Sotgia F, Lisanti MP. Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells. Cell Cycle (Georgetown, Tex.). 10: 4208-16. PMID 22033146 DOI: 10.4161/cc.10.24.18487  0.36
2011 Gravina GL, Marampon F, Piccolella M, Motta M, Ventura L, Pomante R, Popov VM, Zani BM, Pestell RG, Tombolini V, Jannini EA, Festuccia C. Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models. Endocrinology. 152: 4550-61. PMID 21990314 DOI: 10.1210/en.2011-1056  0.36
2011 Sotgia F, Martinez-Outschoorn UE, Pavlides S, Howell A, Pestell RG, Lisanti MP. Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment. Breast Cancer Research : Bcr. 13: 213. PMID 21867571 DOI: 10.1186/bcr2892  0.36
2011 Wang C, Powell M, Tian L, Pestell RG. Analysis of nuclear receptor acetylation. Methods in Molecular Biology (Clifton, N.J.). 776: 169-81. PMID 21796527 DOI: 10.1007/978-1-61779-243-4_11  0.36
2011 Martinez-Outschoorn UE, Lin Z, Trimmer C, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP. Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors. Cell Cycle (Georgetown, Tex.). 10: 2504-20. PMID 21778829 DOI: 10.4161/cc.10.15.16585  0.36
2011 Martinez-Outschoorn UE, Lin Z, Ko YH, Goldberg AF, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP. Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells. Cell Cycle (Georgetown, Tex.). 10: 2521-8. PMID 21768775 DOI: 10.4161/cc.10.15.16584  0.36
2011 Lisanti MP, Martinez-Outschoorn UE, Lin Z, Pavlides S, Whitaker-Menezes D, Pestell RG, Howell A, Sotgia F. Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer". Cell Cycle (Georgetown, Tex.). 10: 2440-9. PMID 21734470 DOI: 10.4161/cc.10.15.16870  0.36
2011 Velasco-Velázquez MA, Li Z, Casimiro M, Loro E, Homsi N, Pestell RG. Examining the role of cyclin D1 in breast cancer. Future Oncology (London, England). 7: 753-65. PMID 21675838 DOI: 10.2217/fon.11.56  0.36
2011 Lisanti MP, Martinez-Outschoorn UE, Pavlides S, Whitaker-Menezes D, Pestell RG, Howell A, Sotgia F. Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine. Cell Cycle (Georgetown, Tex.). 10: 2059-63. PMID 21654190 DOI: 10.4161/cc.10.13.16233  0.36
2011 Velasco-Velázquez MA, Popov VM, Lisanti MP, Pestell RG. The role of breast cancer stem cells in metastasis and therapeutic implications. The American Journal of Pathology. 179: 2-11. PMID 21640330 DOI: 10.1016/j.ajpath.2011.03.005  0.36
2011 DeAngelis T, Wu K, Pestell R, Baserga R. The type 1 insulin-like growth factor receptor and resistance to DACH1. Cell Cycle (Georgetown, Tex.). 10: 1956-9. PMID 21558809 DOI: 10.4161/cc.10.12.15800  0.36
2011 Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics. Cell Cycle (Georgetown, Tex.). 10: 1271-86. PMID 21512313 DOI: 10.4161/cc.10.8.15330  0.36
2011 Janowski E, Jiao X, Katiyar S, Lisanti MP, Liu M, Pestell RG, Morad M. c-Jun is required for TGF-β-mediated cellular migration via nuclear Ca²⁺ signaling. The International Journal of Biochemistry & Cell Biology. 43: 1104-13. PMID 21447400 DOI: 10.1016/j.biocel.2011.03.011  0.36
2011 Marampon F, Gravina GL, Di Rocco A, Bonfili P, Di Staso M, Fardella C, Polidoro L, Ciccarelli C, Festuccia C, Popov VM, Pestell RG, Tombolini V, Zani BM. MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals. Molecular Cancer Therapeutics. 10: 159-68. PMID 21220498 DOI: 10.1158/1535-7163.MCT-10-0631  0.36
2011 Meng H, Tian L, Zhou J, Li Z, Jiao X, Li WW, Plomann M, Xu Z, Lisanti MP, Wang C, Pestell RG. PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b. Cell Cycle (Georgetown, Tex.). 10: 73-81. PMID 21200149  0.36
2011 Powell MJ, Casimiro MC, Cordon-Cardo C, He X, Yeow WS, Wang C, McCue PA, McBurney MW, Pestell RG. Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Research. 71: 964-75. PMID 21189328 DOI: 10.1158/0008-5472.CAN-10-3172  0.36
2011 Wang C, Tian L, Popov VM, Pestell RG. Acetylation and nuclear receptor action. The Journal of Steroid Biochemistry and Molecular Biology. 123: 91-100. PMID 21167281 DOI: 10.1016/j.jsbmb.2010.12.003  0.36
2011 Yu Z, Pestell RG. MicroRNAs and cancer stem cells Micrornas in Cancer Translational Research. 373-388. DOI: 10.1007/978-94-007-0298-1-16  0.36
2011 Powell MJ, Popov VM, Wang X, Mcmahon SB, Mazo A, Pestell RG. The Role of Epigenetic Modifications in Cancer Cancer Epigenetics: Biomolecular Therapeutics For Human Cancer. 113-144. DOI: 10.1002/9781118005743.ch7  0.36
2010 Gravina GL, Festuccia C, Marampon F, Popov VM, Pestell RG, Zani BM, Tombolini V. Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation. Molecular Cancer. 9: 305. PMID 21108789 DOI: 10.1186/1476-4598-9-305  0.36
2010 Zhou J, Liu Y, Zhang W, Popov VM, Wang M, Pattabiraman N, Suñé C, Cvekl A, Wu K, Jiang J, Wang C, Pestell RG. Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. The Journal of Biological Chemistry. 285: 40342-50. PMID 20956529 DOI: 10.1074/jbc.M110.156141  0.36
2010 Katiyar S, Casimiro MC, Dettin L, Ju X, Wagner EF, Tanaka H, Pestell RG. C-jun inhibits mammary apoptosis in vivo. Molecular Biology of the Cell. 21: 4264-74. PMID 20926681 DOI: 10.1091/mbc.E10-08-0705  0.36
2010 Zhou J, Wang C, Wang Z, Dampier W, Wu K, Casimiro MC, Chepelev I, Popov VM, Quong A, Tozeren A, Zhao K, Lisanti MP, Pestell RG. Attenuation of Forkhead signaling by the retinal determination factor DACH1 Proceedings of the National Academy of Sciences of the United States of America. 107: 6864-6869. PMID 20351289 DOI: 10.1073/pnas.1002746107  0.36
2010 Yu Z, Baserga R, Chen L, Wang C, Lisanti MP, Pestell RG. microRNA, cell cycle, and human breast cancer. The American Journal of Pathology. 176: 1058-64. PMID 20075198 DOI: 10.2353/ajpath.2010.090664  0.36
2010 Thakur ML, Devadhas D, Zhang K, Pestell RG, Wang C, McCue P, Wickstrom E. Imaging spontaneous MMTVneu transgenic murine mammary tumors: targeting metabolic activity versus genetic products. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 106-11. PMID 20008985 DOI: 10.2967/jnumed.109.069542  0.36
2010 Popov VM, Wu K, Zhou J, Powell MJ, Mardon G, Wang C, Pestell RG. The Dachshund gene in development and hormone-responsive tumorigenesis. Trends in Endocrinology and Metabolism: Tem. 21: 41-9. PMID 19896866 DOI: 10.1016/j.tem.2009.08.002  0.36
2009 Popov VM, Zhou J, Shirley LA, Quong J, Yeow WS, Wright JA, Wu K, Rui H, Vadlamudi RK, Jiang J, Kumar R, Wang C, Pestell RG. The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling. Cancer Research. 69: 5752-60. PMID 19605405 DOI: 10.1158/0008-5472.CAN-08-3992  0.36
2009 Di Vizio D, Morello M, Sotgia F, Pestell RG, Freeman MR, Lisanti MP. An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation. Cell Cycle (Georgetown, Tex.). 8: 2420-4. PMID 19556867  0.36
2009 Nan F, Lü Q, Zhou J, Cheng L, Popov VM, Wei S, Kong B, Pestell RG, Lisanti MP, Jiang J, Wang C. Altered expression of DACH1 and cyclin D1 in endometrial cancer. Cancer Biology & Therapy. 8: 1534-9. PMID 19502783  0.36
2009 Liu M, Ju X, Willmarth NE, Casimiro MC, Ojeifo J, Sakamaki T, Katiyar S, Jiao X, Popov VM, Yu Z, Wu K, Joyce D, Wang C, Pestell RG. Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. The American Journal of Pathology. 174: 1910-20. PMID 19349372 DOI: 10.2353/ajpath.2009.080706  0.36
2009 Velasco-Velázquez MA, Yu Z, Jiao X, Pestell RG. Cancer stem cells and the cell cycle: Targeting the drive behind breast cancer Expert Review of Anticancer Therapy. 9: 275-279. PMID 19275505 DOI: 10.1586/14737140.9.3.275  0.36
2008 Pezo RC, Gandhi SJ, Shirley LA, Pestell RG, Augenlicht LH, Singer RH. Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors. Cancer Research. 68: 4977-82. PMID 18593893 DOI: 10.1158/0008-5472.CAN-07-6770  0.36
2008 Kim M, Wu X, Song I, Fu M, Chang SH, Lisanti MP, Pestell R. Selective cytotoxicity of synthesized procyanidin 3-O-galloylepicatechin- 4b, 8-3-O-galloylcatechin to human cancer cells Cell Cycle. 7: 1648-1657. PMID 18560275  0.36
2008 Wu K, Katiyar S, Li A, Liu M, Ju X, Popov VM, Jiao X, Lisanti MP, Casola A, Pestell RG. Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. Proceedings of the National Academy of Sciences of the United States of America. 105: 6924-9. PMID 18467491 DOI: 10.1073/pnas.0802085105  0.36
2008 Marampon F, Casimiro MC, Fu M, Powell MJ, Popov VM, Lindsay J, Zani BM, Ciccarelli C, Watanabe G, Lee RJ, Pestell RG. Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB. Molecular Biology of the Cell. 19: 2566-78. PMID 18367547 DOI: 10.1091/mbc.E06-12-1110  0.36
2008 Wang C, Powell MJ, Popov VM, Pestell RG. Acetylation in nuclear receptor signaling and the role of sirtuins. Molecular Endocrinology (Baltimore, Md.). 22: 539-45. PMID 18165438 DOI: 10.1210/me.2007-0379  0.36
2008 Sundaram K, Mani SK, Kitatani K, Wu K, Pestell RG, Reddy SV. DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells. Journal of Cellular Biochemistry. 103: 1747-59. PMID 17891780 DOI: 10.1002/jcb.21561  0.36
2007 Whittle JR, Powell MJ, Popov VM, Shirley LA, Wang C, Pestell RG. Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation. Trends in Endocrinology and Metabolism: Tem. 18: 356-64. PMID 17964799 DOI: 10.1016/j.tem.2007.07.007  0.36
2007 Pavithra L, Rampalli S, Sinha S, Sreenath K, Pestell RG, Chattopadhyay S. Stabilization of SMAR1 mRNA by PGA2 involves a stem-loop structure in the 5′ UTR Nucleic Acids Research. 35: 6004-6016. PMID 17726044 DOI: 10.1093/nar/gkm649  0.36
2007 Avvisato CL, Yang X, Shah S, Hoxter B, Li W, Gaynor R, Pestell R, Tozeren A, Byers SW. Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells. Journal of Cell Science. 120: 2672-82. PMID 17635998 DOI: 10.1242/jcs.03476  0.36
2007 Popov VM, Wang C, Shirley LA, Rosenberg A, Li S, Nevalainen M, Fu M, Pestell RG. The functional significance of nuclear receptor acetylation. Steroids. 72: 221-30. PMID 17291555 DOI: 10.1016/j.steroids.2006.12.001  0.36
2007 Katiyar S, Jiao X, Wagner E, Lisanti MP, Pestell RG. Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor Molecular and Cellular Biology. 27: 1356-1369. PMID 17145782 DOI: 10.1128/MCB.01061-06  0.36
2006 Leader JE, Wang C, Popov VM, Fu M, Pestell RG. Epigenetics and the estrogen receptor. Annals of the New York Academy of Sciences. 1089: 73-87. PMID 17261756 DOI: 10.1196/annals.1386.047  0.36
2006 Sotgia F, Rui H, Bonuccelli G, Mercier I, Pestell RG, Lisanti MP. Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers. Cancer Research. 66: 10647-51. PMID 17108100 DOI: 10.1158/0008-5472.CAN-06-2805  0.36
2006 Li Z, Wang C, Prendergast GC, Pestell RG. Cyclin D1 functions in cell migration. Cell Cycle (Georgetown, Tex.). 5: 2440-2. PMID 17106256 DOI: 10.4161/cc.5.21.3428  0.36
2006 Pestell RG, Li Z. Antisense to cyclin D1 inhibits VEGF-stimulated growth of vascular endothelial cells: Implication of tumor vascularization Clinical Cancer Research. 12: 4459-4462. PMID 16899588 DOI: 10.1158/1078-0432.CCR-06-0614  0.36
2006 Stahl M, Ge C, Shi S, Pestell RG, Stanley P. Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1. Cancer Research. 66: 7562-70. PMID 16885355 DOI: 10.1158/0008-5472.CAN-06-0974  0.36
2006 Leader JE, Wang C, Fu M, Pestell RG. Epigenetic regulation of nuclear steroid receptors Biochemical Pharmacology. 72: 1589-1596. PMID 16844098 DOI: 10.1016/j.bcp.2006.05.024  0.36
2006 Chang YJ, Wu MS, Lin JT, Pestell RG, Blaser MJ, Chen CC. Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle Cellular Microbiology. 8: 1740-1752. PMID 16759223 DOI: 10.1111/j.1462-5822.2006.00743.x  0.36
2006 Yang T, Fu M, Pestell R, Sauve AA. SIRT1 and endocrine signaling. Trends in Endocrinology and Metabolism: Tem. 17: 186-91. PMID 16684606 DOI: 10.1016/j.tem.2006.04.002  0.36
2006 Cui Y, Niu A, Pestell R, Kumar R, Curran EM, Liu Y, Fuqua SA. Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 20: 2020-35. PMID 16645043 DOI: 10.1210/me.2005-0063  0.36
2006 Pestell R. Remembering team science is for the patients Cancer Biology and Therapy. 5: 449-452. PMID 16575209  0.36
2006 Sourisseau T, Georgiadis A, Tsapara A, Ali RR, Pestell R, Matter K, Balda MS. Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA Molecular and Cellular Biology. 26: 2387-2398. PMID 16508013 DOI: 10.1128/MCB.26.6.2387-2398.2006  0.36
2006 Sotgia F, Schubert W, Pestell RG, Lisanti MP. Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyper-activates STAT5a signaling Cancer Biology and Therapy. 5: 292-297. PMID 16418573  0.36
2006 Sotgia F, Williams TM, Schubert W, Medina F, Minetti C, Pestell RG, Lisanti MP. Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. The American Journal of Pathology. 168: 292-309. PMID 16400031 DOI: 10.2353/ajpath.2006.050429  0.36
2006 Yin Y, Yuan H, Wang C, Pattabiraman N, Rao M, Pestell RG, Glazer RI. 3-Phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor- and promotes adipocyte differentiation Molecular Endocrinology. 20: 268-278. PMID 16150867 DOI: 10.1210/me.2005-0197  0.36
2005 Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP. Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling. Cell Cycle (Georgetown, Tex.). 4: 1808-16. PMID 16294019  0.36
2005 Xiao D, Chinnappan D, Pestell R, Albanese C, Weber HC. Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells Cancer Research. 65: 9934-9942. PMID 16267018 DOI: 10.1158/0008-5472.CAN-05-1830  0.36
2005 Lewis JS, Vijayanathan V, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T. Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2. Oncology Research. 15: 113-28. PMID 16050133  0.36
2005 Wu K, D'Amico M, Wang C, Albanese C, Pestell RG, Mani S. A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines. Investigational New Drugs. 23: 299-309. PMID 16012789 DOI: 10.1007/s10637-005-1438-y  0.36
2005 Giampuzzi M, Oleggini R, Albanese C, Pestell R, Di Donato A. beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase. Biochimica Et Biophysica Acta. 1745: 370-81. PMID 15946752 DOI: 10.1016/j.bbamcr.2005.04.012  0.36
2005 Song DH, Kaufman JC, Borodyansky L, Albanese C, Pestell RG, Wolfe MM. Gastrin stabilises beta-catenin protein in mouse colorectal cancer cells. British Journal of Cancer. 92: 1581-7. PMID 15798764 DOI: 10.1038/sj.bjc.6602509  0.36
2005 Lewis JS, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T. Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells. Journal of Molecular Endocrinology. 34: 91-105. PMID 15691880 DOI: 10.1677/jme.1.01599  0.36
2004 Hilakivi-Clarke L, Wang C, Kalil M, Riggins R, Pestell RG. Nutritional modulation of the cell cycle and breast cancer Endocrine-Related Cancer. 11: 603-622. PMID 15613442 DOI: 10.1677/erc.1.00665  0.36
2004 Cui Y, Zhang M, Pestell R, Curran EM, Welshons WV, Fuqua SAW. Phosphorylation of estrogen receptor α blocks its acetylation and regulates estrogen sensitivity Cancer Research. 64: 9199-9208. PMID 15604293 DOI: 10.1158/0008-5472.CAN-04-2126  0.36
2004 Bouras T, Lisanti MP, Pestell RG. Caveolin-1 in breast cancer Cancer Biology and Therapy. 3: 931-941. PMID 15539932  0.36
2004 Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. Minireview: Cyclin D1: Normal and abnormal functions Endocrinology. 145: 5439-5447. PMID 15331580 DOI: 10.1210/en.2004-0959  0.36
2004 Liu MC, Marshall JL, Pestell RG. Novel strategies in cancer therapeutics: Targeting enzymes involved in cell cycle regulation and cellular proliferation Current Cancer Drug Targets. 4: 403-424. PMID 15320717 DOI: 10.2174/1568009043332907  0.36
2004 Fu M, Wang C, Zhang X, Pestell RG. Acetylation of nuclear receptors in cellular growth and apoptosis. Biochemical Pharmacology. 68: 1199-208. PMID 15313417 DOI: 10.1016/j.bcp.2004.05.037  0.36
2004 Fu M, Wang C, Zhang X, Pestell RG. Signal transduction inhibitors in cellular function. Methods in Molecular Biology (Clifton, N.J.). 284: 15-36. PMID 15173606 DOI: 10.1385/1-59259-816-1:015  0.36
2004 Wang C, Li Z, Fu M, Bouras T, Pestell RG. Signal transduction mediated by cyclin D1: from mitogens to cell proliferation: a molecular target with therapeutic potential Cancer Treatment and Research. 119: 217-237. PMID 15164880  0.36
2004 Burbelo P, Wellstein A, Pestell RG. Altered Rho GTPase signaling pathways in breast cancer cells. Breast Cancer Research and Treatment. 84: 43-8. PMID 14999153 DOI: 10.1023/B:BREA.0000018422.02237.f9  0.36
2004 Wang C, Fu M, Pestell RG. Histone acetylation/deacetylation as a regulator of cell cycle gene expression Methods in Molecular Biology (Clifton, N.J.). 241: 207-216. PMID 14970656  0.36
2004 Sharma C, Pradeep A, Pestell RG, Rana B. Peroxisome Proliferator-activated Receptor γ Activation Modulates Cyclin D1 Transcription via β-Catenin-independent and cAMP-response Element-binding Protein-dependent Pathways in Mouse Hepatocytes Journal of Biological Chemistry. 279: 16927-16938. PMID 14764597 DOI: 10.1074/jbc.M309045200  0.36
2004 Bateman NW, Tan D, Pestell RG, Black JD, Black AR. Intestinal tumor progression is associated with altered function of KLF5. The Journal of Biological Chemistry. 279: 12093-101. PMID 14726538 DOI: 10.1074/jbc.M311532200  0.36
2004 Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK, Kumar R. p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. The Journal of Biological Chemistry. 279: 1422-8. PMID 14530270 DOI: 10.1074/jbc.M309937200  0.36
2003 Rosen EM, Fan S, Pestell RG, Goldberg ID. BRCA1 in hormone-responsive cancers. Trends in Endocrinology and Metabolism: Tem. 14: 378-85. PMID 14516936 DOI: 10.1016/j.tem.2003.08.001  0.36
2003 Rowlands TM, Pechenkina IV, Hatsell SJ, Pestell RG, Cowin P. Dissecting the roles of β-catenin and cyclin D1 during mammary development and neoplasia Proceedings of the National Academy of Sciences of the United States of America. 100: 11400-11405. PMID 13679587 DOI: 10.1073/pnas.1534601100  0.36
2003 Shah S, Hecht A, Pestell R, Byers SW. Trans-repression of beta-catenin activity by nuclear receptors. The Journal of Biological Chemistry. 278: 48137-45. PMID 12972427 DOI: 10.1074/jbc.M307154200  0.36
2003 Fu M, Wang C, Zhang X, Pestell R. Nuclear receptor modifications and endocrine cell proliferation. The Journal of Steroid Biochemistry and Molecular Biology. 85: 133-8. PMID 12943697 DOI: 10.1016/S0960-0760(03)00223-1  0.36
2003 Rosen EM, Fan S, Pestell RG, Goldberg ID. BRCA1 gene in breast cancer. Journal of Cellular Physiology. 196: 19-41. PMID 12767038 DOI: 10.1002/jcp.10257  0.36
2003 Hu YL, Albanese C, Pestell RG, Jaffe RB. Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells. Journal of the National Cancer Institute. 95: 733-40. PMID 12759391  0.36
2003 Nelsen CJ, Rickheim DG, Tucker MM, McKenzie TJ, Hansen LK, Pestell RG, Albrecht JH. Amino acids regulate hepatocyte proliferation through modulation of cyclin D1 expression Journal of Biological Chemistry. 278: 25853-25858. PMID 12736274 DOI: 10.1074/jbc.M302360200  0.36
2002 Coulter CL, Pestell RG, Ross JT, Salkeld MD, James S, Bennett HPJ, McMillen IC. Effect of n-proopiomelanocortin (1-77) and (1-49) infusions on adrenal expression of cyclin d1 in the fetal sheep Endocrine Research. 28: 625-629. PMID 12530673 DOI: 10.1081/ERC-120016976  0.36
2002 Lin W, Albanese C, Pestell RG, Lawrence DS. Spatially discrete, light-driven protein expression. Chemistry & Biology. 9: 1347-53. PMID 12498888 DOI: 10.1016/S1074-5521(02)00288-0  0.36
2002 Fu M, Wang C, Wang J, Zafonte BT, Lisanti MP, Pestell RG. Acetylation in hormone signaling and the cell cycle. Cytokine & Growth Factor Reviews. 13: 259-76. PMID 12486878 DOI: 10.1016/S1359-6101(02)00003-5  0.36
2002 Wu K, Wang C, D'Amico M, Lee RJ, Albanese C, Pestell RG, Mani S. Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways. Molecular Cancer Therapeutics. 1: 695-706. PMID 12479366  0.36
2002 Lin HM, Pestell RG, Raz A, Kim HRC. Galectin-3 enhances cyclin D1 promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells Oncogene. 21: 8001-8010. PMID 12439750 DOI: 10.1038/sj.onc.1205820  0.36
2002 Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. The American Journal of Pathology. 161: 1357-69. PMID 12368209 DOI: 10.1016/S0002-9440(10)64412-4  0.36
2002 Albanese C, Hulit J, Sakamaki T, Pestell RG. Recent advances in inducible expression in transgenic mice. Seminars in Cell & Developmental Biology. 13: 129-41. PMID 12240598 DOI: 10.1016/S1084-9521(02)00021-6  0.36
2002 Guha U, Gomes WA, Kobayashi T, Pestell RG, Kessler JA. In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb. Developmental Biology. 249: 108-20. PMID 12217322 DOI: 10.1006/dbio.2002.0752  0.36
2002 Hulit J, Lee RJ, Russell RG, Pestell RG. ErbB-2-induced mammary tumor growth: The role of cyclin D1 and p27Kip1 Biochemical Pharmacology. 64: 827-836. PMID 12213576 DOI: 10.1016/S0006-2952(02)01145-0  0.36
2002 Neumeister P, Albanese C, Balent B, Greally J, Pestell RG. Senescence and epigenetic dysregulation in cancer. The International Journal of Biochemistry & Cell Biology. 34: 1475-90. PMID 12200040 DOI: 10.1016/S1357-2725(02)00079-1  0.36
2002 Zhang ZK, Davies KP, Allen J, Zhu L, Pestell RG, Zagzag D, Kalpana GV. Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Molecular and Cellular Biology. 22: 5975-88. PMID 12138206 DOI: 10.1128/MCB.22.16.5975-5988.2002  0.36
2002 Suzui M, Masuda M, Lim JT, Albanese C, Pestell RG, Weinstein IB. Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1. Cancer Research. 62: 3997-4006. PMID 12124333  0.36
2002 Shivakumar L, Minna J, Sakamaki T, Pestell R, White MA. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation Molecular and Cellular Biology. 22: 4309-4318. PMID 12024041 DOI: 10.1128/MCB.22.12.4309-4318.2002  0.36
2002 Bearss DJ, Lee RJ, Troyer DA, Pestell RG, Windle JJ. Differential effects of p21WAF1/CIP1 deficiency on MMTV-ras and MMTV-myc mammary tumor properties Cancer Research. 62: 2077-2084. PMID 11929828  0.36
2002 Amanatullah DF, Zafonte BT, Pestell RG. The cell cycle in steroid hormone regulated proliferation and differentiation Minerva Endocrinologica. 27: 7-20. PMID 11845110  0.36
2002 Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP. Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. The Journal of Biological Chemistry. 277: 16464-9. PMID 11815623 DOI: 10.1074/jbc.M112274200  0.36
2002 Dadachova E, Bouzahzah B, Zuckier LS, Pestell RG. Rhenium-188 as an alternative to Iodine-131 for treatment of breast tumors expressing the sodium/iodide symporter (NIS) Nuclear Medicine and Biology. 29: 13-18. PMID 11786271 DOI: 10.1016/S0969-8051(01)00279-7  0.36
2002 Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, Hull MA. Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis. 23: 107-14. PMID 11756231  0.36
2002 Neumeister P, Pestell R, Balent B, Jaeger G, Linkesch W, Sill H. Myelodysplastic syndrome: Etiology, prognosis and management American Journal of Cancer. 1: 301-311. DOI: 10.2165/00024669-200201050-00001  0.36
2001 Zhao J, Pestell R, Guan JL. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression Molecular Biology of the Cell. 12: 4066-4077. PMID 11739801  0.36
2001 Park DS, Lee H, Riedel C, Hulit J, Scherer PE, Pestell RG, Lisanti MP. Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism. The Journal of Biological Chemistry. 276: 48389-97. PMID 11602600 DOI: 10.1074/jbc.M108210200  0.36
2001 Schlegel A, Wang C, Pestell RG, Lisanti MP. Ligand-independent activation of oestrogen receptor alpha by caveolin-1. The Biochemical Journal. 359: 203-10. PMID 11563984 DOI: 10.1042/0264-6021:3590203  0.36
2001 Hulit J, Di Vizio D, Pestell RG. Inducible transgenics. New lessons on events governing the induction and commitment in mammary tumorigenesis Breast Cancer Research. 3: 209-212. PMID 11434870 DOI: 10.1186/bcr297  0.36
2001 Zafonte BT, Amanatullah DF, Sage D, Augenlicht LH, Pestell RG. Ras regulation of cyclin-dependent immunoprecipitation kinase assays Methods in Enzymology. 333: 127-138. PMID 11400330 DOI: 10.1016/S0076-6879(01)33051-3  0.36
2001 Amanatullah DF, Zafonte BT, Albanese C, Fu M, Messiers C, Hassell J, Pestell RG. Ras regulation of cyclin D1 promoter Methods in Enzymology. 333: 116-127. PMID 11400329 DOI: 10.1016/S0076-6879(01)33050-1  0.36
2001 Allan AL, Albanese C, Pestell RG, LaMarre J. Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes. The Journal of Biological Chemistry. 276: 27272-80. PMID 11375399 DOI: 10.1074/jbc.M103196200  0.36
2001 Condeelis JS, Wyckoff JB, Bailly M, Pestell R, Lawrence D, Backer J, Segall JE. Lamellipodia in invasion Seminars in Cancer Biology. 11: 119-128. PMID 11322831 DOI: 10.1006/scbi.2000.0363  0.36
2001 Lin HM, Lee YJ, Li G, Pestell RG, Kim HRC. Bcl-2 induces cyclin D1 promoter activity in human breast epithelial cells independent of cell anchorage Cell Death and Differentiation. 8: 44-50. PMID 11313702 DOI: 10.1038/sj.cdd.4400770  0.36
2001 Joyce D, Albanese C, Steer J, Fu M, Bouzahzah B, Pestell RG. NF-κB and cell-cycle regulation: The cyclin connection Cytokine and Growth Factor Reviews. 12: 73-90. PMID 11312120 DOI: 10.1016/S1359-6101(00)00018-6  0.36
2001 Wang C, Fu M, Mani S, Wadler S, Senderowicz AM, Pestell RG. Histone acetylation and the cell-cycle in cancer Frontiers in Bioscience : a Journal and Virtual Library. 6. PMID 11282573  0.36
2001 Soriano S, Kang DE, Fu M, Pestell R, Chevallier N, Zheng H, Koo EH. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing. The Journal of Cell Biology. 152: 785-94. PMID 11266469 DOI: 10.1083/jcb.152.4.785  0.36
2001 Volonté D, Galbiati F, Pestell RG, Lisanti MP. Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr14) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress Journal of Biological Chemistry. 276: 8094-8103. PMID 11094059 DOI: 10.1074/jbc.M009245200  0.36
2000 Schlegel A, Pestell RG, Lisanti MP. Caveolins in cholesterol trafficking and signal transduction: implications for human disease. Frontiers in Bioscience : a Journal and Virtual Library. 5: D929-37. PMID 11102315  0.36
2000 Razani B, Altschuler Y, Zhu L, Pestell RG, Mostov KE, Lisanti MP. Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation. Biochemistry. 39: 13916-24. PMID 11076533 DOI: 10.1021/bi001489b  0.36
2000 Bailly M, Wyckoff J, Bouzahzah B, Hammerman R, Sylvestre V, Cammer M, Pestell R, Segall JE. Epidermal growth factor receptor distribution during chemotactic responses. Molecular Biology of the Cell. 11: 3873-83. PMID 11071913  0.36
2000 Mani S, Wang C, Wu K, Francis R, Pestell R. Cyclin-dependent kinase inhibitors: Novel anticancer agents Expert Opinion On Investigational Drugs. 9: 1849-1870. PMID 11060782  0.36
2000 Yu B, Lane ME, Pestell RG, Albanese C, Wadler S. Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein Molecular Cell Biology Research Communications. 3: 352-359. PMID 11032757 DOI: 10.1006/mcbr.2000.0238  0.36
2000 Henry DO, Moskalenko SA, Kaur KJ, Fu M, Pestell RG, Camonis JH, White MA. Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB. Molecular and Cellular Biology. 20: 8084-92. PMID 11027278 DOI: 10.1128/MCB.20.21.8084-8092.2000  0.36
2000 Page K, Li J, Wang Y, Kartha S, Pestell RG, Hershenson MB. Regulation of cyclin D(1) expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 23: 436-43. PMID 11017907 DOI: 10.1165/ajrcmb.23.4.3953  0.36
2000 Pruitt K, Pestell RG, Der CJ. Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells. The Journal of Biological Chemistry. 275: 40916-24. PMID 11007784 DOI: 10.1074/jbc.M006682200  0.36
2000 Shie JL, Chen ZY, O'Brien MJ, Pestell RG, Lee ME, Tseng CC. Role of gut-enriched Kruppel-like factor in colonic cell growth and differentiation American Journal of Physiology - Gastrointestinal and Liver Physiology. 279. PMID 11005769  0.36
2000 Bouzahzah B, Fu M, Iavarone A, Factor VM, Thorgeirsson SS, Pestell RG. Transforming growth factor-β1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo Cancer Research. 60: 4531-4537. PMID 10969803  0.36
2000 Shie JL, Chen ZY, Fu M, Pestell RG, Tseng CC. Gut-enriched Kruppel-like factor represess cyclin D1 promoter activity through Sp1 motif Nucleic Acids Research. 28: 2969-2976. PMID 10908361  0.36
2000 Petkova SB, Ashton A, Bouzahzah B, Huang H, Pestell RG, Tanowitz HB. Cell cycle molecules and diseases of the cardiovascular system Frontiers in Bioscience : a Journal and Virtual Library. 5. PMID 10762598  0.36
2000 Amanatullah DF, Reutens AT, Zafonte BT, Fu M, Mani S, Pestell RG. Cell-cycle dysregulation and the molecular mechanisms of prostate cancer Frontiers in Bioscience : a Journal and Virtual Library. 5. PMID 10762592  0.36
2000 Zhang W, Razani B, Altschuler Y, Bouzahzah B, Mostov KE, Pestell RG, Lisanti MP. Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1. The Journal of Biological Chemistry. 275: 20717-25. PMID 10748172 DOI: 10.1074/jbc.M909895199  0.36
2000 Bregman DB, Pestell RG, Kidd VJ. Cell cycle regulation and RNA polymerase II Frontiers in Bioscience : a Journal and Virtual Library. 5. PMID 10704151  0.36
2000 Shambaugh GE, Haines GK, Koch A, Lee EJK, Zhou JN, Pestell R. Immunohistochemical examination of the INK4 and Cip inhibitors in the rat neonatal cerebellum: Cellular localization and the impact of protein calorie malnutrition Brain Research. 855: 11-22. PMID 10650125 DOI: 10.1016/S0006-8993(99)02028-4  0.36
1999 Schlegel A, Wang C, Katzenellenbogen BS, Pestell RG, Lisanti MP. Caveolin-1 potentiates estrogen receptor alpha (ERalpha) signaling. caveolin-1 drives ligand-independent nuclear translocation and activation of ERalpha. The Journal of Biological Chemistry. 274: 33551-6. PMID 10559241 DOI: 10.1074/jbc.274.47.33551  0.36
1999 Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity. The Journal of Biological Chemistry. 274: 32333-41. PMID 10542274 DOI: 10.1074/jbc.274.45.32333  0.36
1999 Carlson B, Lahusen T, Singh S, Loaiza-Perez A, Worland PJ, Pestell R, Albanese C, Sausville EA, Senderowicz AM. Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol Cancer Research. 59: 4634-4641. PMID 10493518  0.36
1999 Pestell RG, Albanese C, Reutens AT, Segall JE, Lee RJ, Arnold A. The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocrine Reviews. 20: 501-34. PMID 10453356 DOI: 10.1210/edrv.20.4.0373  0.36
1999 Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Molecular and Cellular Biology. 19: 5785-99. PMID 10409765  0.36
1999 Ashton AW, Watanabe G, Albanese C, Harrington EO, Ware JA, Pestell RG. Protein kinase Cdelta inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27(Kip1). The Journal of Biological Chemistry. 274: 20805-11. PMID 10409620 DOI: 10.1074/jbc.274.30.20805  0.36
1999 Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway Proceedings of the National Academy of Sciences of the United States of America. 96: 5522-5527. PMID 10318916 DOI: 10.1073/pnas.96.10.5522  0.36
1999 Beier F, Lee RJ, Taylor AC, Pestell RG, Luvalle P. Identification of the cyclin D1 gene as a target of activating transcription factor 2 in chondrocytes Proceedings of the National Academy of Sciences of the United States of America. 96: 1433-1438. PMID 9990041 DOI: 10.1073/pnas.96.4.1433  0.36
1999 Musa NL, Ramakrishnan M, Li J, Kartha S, Liu P, Pestell RG, Hershenson MB. Forskolin inhibits cyclin D1 expression in cultured airway smooth-muscle cells. American Journal of Respiratory Cell and Molecular Biology. 20: 352-8. PMID 9922228 DOI: 10.1165/ajrcmb.20.2.3160  0.36
1998 Galbiati F, Volonte D, Engelman JA, Watanabe G, Burk R, Pestell RG, Lisanti MP. Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. The Embo Journal. 17: 6633-48. PMID 9822607 DOI: 10.1093/emboj/17.22.6633  0.36
1998 Watanabe G, Pena P, Shambaugh GE, Haines GK, Pestell RG. Regulation of cyclin dependent kinase inhibitor proteins during neonatal cerebella development Developmental Brain Research. 108: 77-87. PMID 9693786 DOI: 10.1016/S0165-3806(98)00032-7  0.36
1998 Westwick JK, Lee RJ, Lambert QT, Symons M, Pestell RG, Der CJ, Whitehead IP. Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun Journal of Biological Chemistry. 273: 16739-16747. PMID 9642229 DOI: 10.1074/jbc.273.27.16739  0.36
1998 Ramakrishnan M, Musa NL, Li J, Liu PT, Pestell RG, Hershenson MB. Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in primary tracheal myocytes. American Journal of Respiratory Cell and Molecular Biology. 18: 736-40. PMID 9618377 DOI: 10.1165/ajrcmb.18.6.3152  0.36
1998 Watanabe G, Albanese C, Lee RJ, Reutens A, Vairo G, Henglein B, Pestell RG. Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1 Molecular and Cellular Biology. 18: 3212-3222. PMID 9584162  0.36
1998 Akama KT, Albanese C, Pestell RG, Van Eldik LJ. Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 95: 5795-800. PMID 9576964 DOI: 10.1073/pnas.95.10.5795  0.36
1997 Li X, Hales KH, Watanabe G, Lee RJ, Pestell RG, Hales DB. The effect of tumor necrosis factor-alpha and cAMP on induction of AP-1 activity in MA-10 tumor Leydig cells. Endocrine. 6: 317-24. PMID 9368689 DOI: 10.1007/BF02820509  0.36
1997 Xiong W, Pestell R, Rosner MR. Role of cyclins in neuronal differentiation of immortalized hippocampal cells Molecular and Cellular Biology. 17: 6585-6597. PMID 9343422  0.36
1997 Thurston VC, Pena P, Pestell R, Binder LI. Nucleolar localization of the microtubule-associated protein tau in neuroblastomas using sense and anti-sense transfection strategies Cell Motility and the Cytoskeleton. 38: 100-110. PMID 9295144 DOI: 10.1002/(SICI)1097-0169(1997)38:1<100::AID-CM9>3.0.CO;2-C  0.36
1997 Watanabe G, Pena P, Albanese C, Wilsbacher LD, Young JB, Pestell RG. Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo. The Journal of Biological Chemistry. 272: 20063-9. PMID 9242678 DOI: 10.1074/jbc.272.32.20063  0.36
1997 Xiong W, Pestell RG, Watanabe G, Li J, Rosner MR, Hershenson MB. Cyclin D1 is required for S phase traversal in bovine tracheal myocytes. The American Journal of Physiology. 272: L1205-10. PMID 9227524  0.36
1997 Johnson W, Albanese C, Handwerger S, Williams T, Pestell RG, Jameson JL. Regulation of the human chorionic gonadotropin α- and β-subunit promoters by AP-2 Journal of Biological Chemistry. 272: 15405-15412. PMID 9182571 DOI: 10.1074/jbc.272.24.15405  0.36
1996 Watanabe G, Lee RJ, Albanese C, Rainey WE, Batlle D, Pestell RG. Angiotensin II activation of cyclin D1-dependent kinase activity Journal of Biological Chemistry. 271: 22570-22577. PMID 8798425 DOI: 10.1074/jbc.271.37.22570  0.36
1996 Sundaresan S, Colin IM, Pestell RG, Jameson JL. Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C. Endocrinology. 137: 304-11. PMID 8536629 DOI: 10.1210/endo.137.1.8536629  0.36
1995 Pestell RG, Albanese C, Watanabe G, Johnson J, Eklund N, Lastowiecki P, Jameson JL. Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter Journal of Biological Chemistry. 270: 18301-18308. PMID 7629150 DOI: 10.1074/jbc.270.31.18301  0.36
1995 Albanese C, Johnson J, Watanabe G, Eklund N, Vu D, Arnold A, Pestell RG. Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions Journal of Biological Chemistry. 270: 23589-23597. PMID 7559524  0.36
1994 Pestell RG, Hollenberg AN, Albanese C, Jameson JL. c-Jun represses transcription of the human chorionic gonadotropin α and β genes through distinct types of CREs Journal of Biological Chemistry. 269: 31090-31096. PMID 7983049  0.36
1994 Hollenberg AN, Pestell RG, Albanese C, Boers ME, Jameson JL. Multiple promoter elements in the human chorionic gonadotropin β subunit genes distinguish their expression from the luteinizing hormone β gene Molecular and Cellular Endocrinology. 106: 111-119. PMID 7534731 DOI: 10.1016/0303-7207(94)90192-9  0.36
1993 Pestell RG, Ward GM, Galvin P, Best JD, Alford FP. Impaired glucose tolerance after endurance exercise is associated with reduced insulin secretion rather than altered insulin sensitivity Metabolism. 42: 277-282. PMID 8487644 DOI: 10.1016/0026-0495(93)90074-X  0.36
1993 Pestell RG, Hammond VE, Crawford RJ. Molecular cloning and characterization of the cyclic AMP-responsive ovine CYP11A1 (cholesterol side-chain cleavage) gene promoter: DNase 1 protection of conserved consensus elements Journal of Molecular Endocrinology. 10: 297-311. PMID 8373514  0.36
1992 Galvin P, Ward G, Walters J, Pestell R, Koschmann M, Vaag A, Martin I, Best JD, Alford F. A simple method for quantitation of insulin sensitivity and insulin release from an intravenous glucose tolerance test Diabetic Medicine. 9: 921-928. PMID 1478037  0.36
1991 Pestell RG, Kirsner RLG, Best JD. Validation and evaluation of test for sympathetic cholinergic function in diabetes mellitus Diabetes. 40: 867-872. PMID 2060722  0.36
1991 Pestell R, Herington A, Best J, Boolell M, McKelvie P, Arnott R, Alford F. Growth hormone excess and galactorrhoea without acromegalic features. Case reports. British Journal of Obstetrics and Gynaecology. 98: 92-7. PMID 1998639  0.36
1991 Pestell R, Ball JRB. Authoritarianism among medicine and law students Australian and New Zealand Journal of Psychiatry. 25: 265-269. PMID 1877963 DOI: 10.3109/00048679109077744  0.36
1991 Page R, Boolell M, Kalfas A, Sawyer S, Pestell R, Ward G, Alford F. Insulin secretion, insulin sensitivity and glucose-mediated glucose disposal in Cushing's disease: A minimal model analysis Clinical Endocrinology. 35: 509-517. PMID 1769133  0.36
1990 Chamberlain KG, Pestell RG, Best JD. Platelet catecholamine contents are cumulative indexes of sympathoadrenal activity American Journal of Physiology - Endocrinology and Metabolism. 259. PMID 2382708  0.36
1990 Best JD, Alford FP, Martin IK, Pestell RG, Ward GM. Practical application of methods for in vivo assessment of insulin secretion and action Hormone and Metabolic Research. 24: 60-66. PMID 2272628  0.36
1990 Pestell R, Alford F, Ramos R, Sawyer S, Best J, Ward G. Insulin secretion, insulin sensitivity and glucose-mediated glucose disposal in thyrotoxicosis: A minimal model analysis Clinical Endocrinology. 33: 481-493. PMID 2225490  0.36
1990 Arnott RD, Pestell RG, McKelvie PA, Henderson JK, McNeill PM, Alford FP. A critical evaluation of transsphenoidal pituitary surgery in the treatment of Cushing's disease: prediction of outcome. Acta Endocrinologica. 123: 423-30. PMID 2173325  0.36
1990 Pestell RG, Best JD, Alford FP. Lymphocytic hypophysitis. The clinical spectrum of the disorder and evidence for an autoimmune pathogenesis Clinical Endocrinology. 33: 457-466. PMID 2121396  0.36
1989 Pestell RG, Alford FP, Best JD. Familial acromegaly Acta Endocrinologica. 121: 286-289. PMID 2773624  0.36
1989 Pestell RG, Hurley DM, Vandongen R. Biochemical and hormonal changes during a 1000 km ultramarathon Clinical and Experimental Pharmacology and Physiology. 16: 353-361. PMID 2548778  0.36
1989 Pestell RG, Crock PA, Ward GM, Alford FP, Best JD. Fenfluramine increases insulin action in patients with NIDDM Diabetes Care. 12: 252-258. PMID 2495916  0.36
1989 Pestell RG, Taylor RR. Effect of cigarette smoking on the frequency of ventricular premature complexes in normal subjects Clinical and Experimental Pharmacology and Physiology. 16: 647-650. PMID 2477179  0.36
1988 Crock PA, Pestell RG, Calenti AJ, Gilford EJ, Henderson JK, Best JD, Alford FP. Multiple pituitary hormone gradients from inferior petrosal sinus sampling in Cushing's disease Acta Endocrinologica. 119: 75-80. PMID 2842995  0.36
1987 Pestell RG, Barr AL, Brand G. Vitamin C and congestive cardiac failure Medical Journal of Australia. 147: 153-154. PMID 3600482  0.36
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