Georges Mer - Publications

Biochemistry and Molecular Biology College of Medicine - Mayo Clinic 

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Botuyan MV, Cui G, Drané P, Oliveira C, Detappe A, Brault ME, Parnandi N, Chaubey S, Thompson JR, Bragantini B, Zhao D, Chapman JR, Chowdhury D, Mer G. Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nature Structural & Molecular Biology. PMID 29967538 DOI: 10.1038/s41594-018-0083-z  0.36
2015 Baets J, Duan X, Wu Y, Smith G, Seeley WW, Mademan I, McGrath NM, Beadell NC, Khoury J, Botuyan MV, Mer G, Worrell GA, Hojo K, DeLeon J, Laura M, et al. Defects of mutant DNMT1 are linked to a spectrum of neurological disorders. Brain : a Journal of Neurology. 138: 845-61. PMID 25678562 DOI: 10.1093/brain/awv010  0.36
2015 Tong Q, Mazur SJ, Rincon-Arano H, Rothbart SB, Kuznetsov DM, Cui G, Liu WH, Gete Y, Klein BJ, Jenkins L, Mer G, Kutateladze AG, Strahl BD, Groudine M, Appella E, et al. An acetyl-methyl switch drives a conformational change in p53. Structure (London, England : 1993). 23: 322-31. PMID 25651062 DOI: 10.1016/j.str.2014.12.010  0.36
2015 Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL, Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM, et al. Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. Acs Chemical Biology. 10: 1072-81. PMID 25590533 DOI: 10.1021/cb500956g  0.36
2015 Tong Q, Cui G, Botuyan MV, Rothbart SB, Hayashi R, Musselman CA, Singh N, Appella E, Strahl BD, Mer G, Kutateladze TG. Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1. Structure (London, England : 1993). 23: 312-21. PMID 25579814 DOI: 10.1016/j.str.2014.11.013  0.36
2015 Xu C, Cui G, Botuyan MV, Mer G. Methyllysine recognition by the royal family modules: Chromo, tudor, MBT, chromo barrel, and PWWP domains Histone Recognition. 49-82. DOI: 10.1007/978-3-319-18102-8_3  0.36
2014 Klein CJ, Wu Y, Vogel P, Goebel HH, Bönnemann C, Zukosky K, Botuyan MV, Duan X, Middha S, Atkinson EJ, Mer G, Dyck PJ. Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons. Neurology. 82: 873-8. PMID 24500646 DOI: 10.1212/WNL.0000000000000206  0.36
2013 Tang J, Cho NW, Cui G, Manion EM, Shanbhag NM, Botuyan MV, Mer G, Greenberg RA. Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nature Structural & Molecular Biology. 20: 317-25. PMID 23377543 DOI: 10.1038/nsmb.2499  0.36
2013 Klein CJ, Bird T, Ertekin-Taner N, Lincoln S, Hjorth R, Wu Y, Kwok J, Mer G, Dyck PJ, Nicholson GA. DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss. Neurology. 80: 824-8. PMID 23365052 DOI: 10.1212/WNL.0b013e318284076d  0.36
2013 Cui G, Botuyan MV, Mer G. (1)H, (15)N and (13)C resonance assignments for the three LOTUS RNA binding domains of Tudor domain-containing protein TDRD7. Biomolecular Nmr Assignments. 7: 79-83. PMID 22481467 DOI: 10.1007/s12104-012-9382-1  0.36
2012 Ramachandran PL, Craig TA, Atanasova EA, Cui G, Owen BA, Bergen HR, Mer G, Kumar R. The potassium channel interacting protein 3 (DREAM/KChIP3) heterodimerizes with and regulates calmodulin function. The Journal of Biological Chemistry. 287: 39439-48. PMID 23019329 DOI: 10.1074/jbc.M112.398495  0.36
2012 Singh N, Basnet H, Wiltshire TD, Mohammad DH, Thompson JR, Héroux A, Botuyan MV, Yaffe MB, Couch FJ, Rosenfeld MG, Mer G. Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1. Proceedings of the National Academy of Sciences of the United States of America. 109: 14381-6. PMID 22908299 DOI: 10.1073/pnas.1212366109  0.36
2012 Cui G, Park S, Badeaux AI, Kim D, Lee J, Thompson JR, Yan F, Kaneko S, Yuan Z, Botuyan MV, Bedford MT, Cheng JQ, Mer G. PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nature Structural & Molecular Biology. 19: 916-24. PMID 22864287 DOI: 10.1038/nsmb.2353  0.36
2012 Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. The Embo Journal. 31: 1865-78. PMID 22373579 DOI: 10.1038/emboj.2012.47  0.36
2012 Fazly A, Li Q, Hu Q, Mer G, Horazdovsky B, Zhang Z. Histone chaperone Rtt106 promotes nucleosome formation using (H3-H4)2 tetramers. The Journal of Biological Chemistry. 287: 10753-60. PMID 22337870 DOI: 10.1074/jbc.M112.347450  0.36
2012 Su D, Hu Q, Li Q, Thompson JR, Cui G, Fazly A, Davies BA, Botuyan MV, Zhang Z, Mer G. Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106. Nature. 483: 104-7. PMID 22307274 DOI: 10.1038/nature10861  0.36
2012 Singh N, Wiltshire TD, Thompson JR, Mer G, Couch FJ. Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex. The Journal of Biological Chemistry. 287: 2854-62. PMID 22139841 DOI: 10.1074/jbc.M111.307868  0.36
2011 Bian C, Xu C, Ruan J, Lee KK, Burke TL, Tempel W, Barsyte D, Li J, Wu M, Zhou BO, Fleharty BE, Paulson A, Allali-Hassani A, Zhou JQ, Mer G, et al. Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. The Embo Journal. 30: 2829-42. PMID 21685874 DOI: 10.1038/emboj.2011.193  0.36
2011 Klein CJ, Botuyan MV, Wu Y, Ward CJ, Nicholson GA, Hammans S, Hojo K, Yamanishi H, Karpf AR, Wallace DC, Simon M, Lander C, Boardman LA, Cunningham JM, Smith GE, ... ... Mer G, et al. Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nature Genetics. 43: 595-600. PMID 21532572 DOI: 10.1038/ng.830  0.36
2011 Su D, Hu Q, Zhou H, Thompson JR, Xu RM, Zhang Z, Mer G. Structure and histone binding properties of the Vps75-Rtt109 chaperone-lysine acetyltransferase complex. The Journal of Biological Chemistry. 286: 15625-9. PMID 21454705 DOI: 10.1074/jbc.C111.220715  0.36
2010 Cui G, Benirschke RC, Tuan HF, Juranić N, Macura S, Botuyan MV, Mer G. Structural basis of ubiquitin recognition by translesion synthesis DNA polymerase ι. Biochemistry. 49: 10198-207. PMID 21049971 DOI: 10.1021/bi101303t  0.36
2010 Benirschke RC, Thompson JR, Nominé Y, Wasielewski E, Juranić N, Macura S, Hatakeyama S, Nakayama KI, Botuyan MV, Mer G. Molecular basis for the association of human E4B U box ubiquitin ligase with E2-conjugating enzymes UbcH5c and Ubc4. Structure (London, England : 1993). 18: 955-65. PMID 20696396 DOI: 10.1016/j.str.2010.04.017  0.36
2010 Lukat-Rodgers GS, Correia C, Botuyan MV, Mer G, Rodgers KR. Heme-based sensing by the mammalian circadian protein CLOCK. Inorganic Chemistry. 49: 6349-65. PMID 20666392 DOI: 10.1021/ic902388q  0.36
2010 Chadli A, Felts SJ, Wang Q, Sullivan WP, Botuyan MV, Fauq A, Ramirez-Alvarado M, Mer G. Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23. The Journal of Biological Chemistry. 285: 4224-31. PMID 19996313 DOI: 10.1074/jbc.M109.081018  0.36
2009 Cui G, Botuyan MV, Mer G. Preparation of recombinant peptides with site- and degree-specific lysine (13)C-methylation. Biochemistry. 48: 3798-800. PMID 19334741 DOI: 10.1021/bi900348z  0.36
2008 Xu C, Cui G, Botuyan MV, Mer G. Structural basis for the recognition of methylated histone H3K36 by the Eaf3 subunit of histone deacetylase complex Rpd3S. Structure (London, England : 1993). 16: 1740-50. PMID 18818090 DOI: 10.1016/j.str.2008.08.008  0.36
2008 Nominé Y, Botuyan MV, Bajzer Z, Owen WG, Caride AJ, Wasielewski E, Mer G. Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations. Biochemistry. 47: 9866-79. PMID 18717574 DOI: 10.1021/bi702247d  0.36
2008 Xu C, Wu L, Cui G, Botuyan MV, Chen J, Mer G. Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites. Journal of Molecular Biology. 381: 361-72. PMID 18582474 DOI: 10.1016/j.jmb.2008.05.087  0.36
2008 Park S, Lim BB, Perez-Terzic C, Mer G, Terzic A. Interaction of asymmetric ABCC9-encoded nucleotide binding domains determines KATP channel SUR2A catalytic activity. Journal of Proteome Research. 7: 1721-8. PMID 18311911 DOI: 10.1021/pr7007847  0.36
2008 Lee J, Thompson JR, Botuyan MV, Mer G. Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nature Structural & Molecular Biology. 15: 109-11. PMID 18084306 DOI: 10.1038/nsmb1326  0.36
2007 Wood JL, Singh N, Mer G, Chen J. MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage. The Journal of Biological Chemistry. 282: 35416-23. PMID 17925396 DOI: 10.1074/jbc.M705245200  0.36
2006 Botuyan MV, Lee J, Ward IM, Kim JE, Thompson JR, Chen J, Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell. 127: 1361-73. PMID 17190600 DOI: 10.1016/j.cell.2006.10.043  0.36
2006 Ward I, Kim JE, Minn K, Chini CC, Mer G, Chen J. The tandem BRCT domain of 53BP1 is not required for its repair function. The Journal of Biological Chemistry. 281: 38472-7. PMID 17043355 DOI: 10.1074/jbc.M607577200  0.36
2006 Gao F, Mer G, Tonelli M, Hansen SB, Burghardt TP, Taylor P, Sine SM. Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop. Molecular Pharmacology. 70: 1230-5. PMID 16847142 DOI: 10.1124/mol.106.027185  0.36
2004 Botuyan MV, Nominé Y, Yu X, Juranic N, Macura S, Chen J, Mer G. Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains. Structure (London, England : 1993). 12: 1137-46. PMID 15242590 DOI: 10.1016/j.str.2004.06.002  0.36
2003 Yu X, Chini CC, He M, Mer G, Chen J. The BRCT domain is a phospho-protein binding domain. Science (New York, N.Y.). 302: 639-42. PMID 14576433 DOI: 10.1126/science.1088753  0.36
2001 Botuyan MV, Mer G, Yi GS, Koth CM, Case DA, Edwards AM, Chazin WJ, Arrowsmith CH. Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide Journal of Molecular Biology. 312: 177-186. PMID 11545595 DOI: 10.1006/jmbi.2001.4938  0.36
2000 Mer G, Bochkarev A, Chazin WJ, Edwards AM. Three-dimensional structure and function of replication protein A Cold Spring Harbor Symposia On Quantitative Biology. 65: 193-200. PMID 12760033  0.36
2000 Mer G, Bochkarev A, Gupta R, Bochkareva E, Frappier L, Ingles CJ, Edwards AM, Chazin WJ. Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA Cell. 103: 449-456. PMID 11081631  0.36
2000 Mer G, Edwards AM, Chazin WJ. Letter to the editor: 1H, 15N and 13C resonance assignments for the C-terminal protein interaction region of the 32 kDa subunit of human replication protein A [3] Journal of Biomolecular Nmr. 17: 179-180. PMID 10921783 DOI: 10.1023/A:1008306832408  0.36
1999 Botuyan MV, Koth CM, Mer G, Chakrabartty A, Conaway JW, Conaway RC, Edwards AM, Arrowsmith CH, Chazin WJ. Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C Proceedings of the National Academy of Sciences of the United States of America. 96: 9033-9038. PMID 10430890 DOI: 10.1073/pnas.96.16.9033  0.36
1999 Kellenberger E, Mer G, Kellenberger C, Marguerie G, Lefèvre JF. Solution structure of a conformationally constrained Arg-Gly-Asp-like motif inserted into the alpha/beta scaffold of leiurotoxin I. European Journal of Biochemistry / Febs. 260: 810-7. PMID 10103011 DOI: 10.1046/j.1432-1327.1999.00218.x  0.36
1998 Mer G, Kellenberger E, Lefèvre JF. Alpha-helix mimicry of a beta-turn. Journal of Molecular Biology. 281: 235-40. PMID 9698544 DOI: 10.1006/jmbi.1998.1939  0.36
1998 Mer G, Chazin WJ. Enzymatic synthesis of region-specific isotope-labeled DNA oligomers for NMR analysis Journal of the American Chemical Society. 120: 607-608. DOI: 10.1021/ja973267f  0.36
1996 Mer G, Hietter H, Kellenberger C, Renatus M, Luu B, Lefèvre JF. Solution structure of PMP-C: A new fold in the group of small serine proteinase inhibitors Journal of Molecular Biology. 258: 158-171. PMID 8613985 DOI: 10.1006/jmbi.1996.0240  0.36
1996 Mer G, Hietter H, Lefèvre JF. Stabilization of proteins by glycosylation examined by NMR analysis of a fucosylated proteinase inhibitor Nature Structural Biology. 3: 45-53. PMID 8548454 DOI: 10.1038/nsb0196-45  0.36
1996 Mer G, Dejaegere A, Stote R, Kieffer B, Lefèvre JF. Structural dynamics of PMP-D2: An experimental and theoretical study Journal of Physical Chemistry. 100: 2667-2674.  0.36
1994 Kieffer B, Mer G, Mann A, Lefevre JF. Structural studies of two antiaggregant RGDW peptides by 1H and 13C NMR International Journal of Peptide and Protein Research. 44: 70-79. PMID 7960407  0.36
1994 Mer G, Kellenberger C, Koehl P, Stote R, Sorokine O, Van Dorsselaer A, Luu B, Hietter H, Lefèvre JF. Solution structure of PMP-D2, a 35-residue peptide isolated from the insect Locusta migratoria Biochemistry. 33: 15397-15407. PMID 7803403  0.36
1991 Wei BY, Gervois N, Mer G, Adorini L, Benoist C, Mathis D. Local structure of a peptide contact site on a(Formula presented) International Immunology. 3: 833-837. PMID 1911551 DOI: 10.1093/intimm/3.8.833  0.36
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