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Eric M. Pietras, Ph.D. - Publications

Affiliations: 
2008 University of California, Los Angeles, Los Angeles, CA 
Area:
Microbiology Biology, Molecular Biology, Immunology
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68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Li J, Malouf C, Miles LA, Willis MB, Pietras EM, King KY. Chronic inflammation can transform the fate of normal and mutant haematopoietic stem cells. Experimental Hematology. PMID 37647982 DOI: 10.1016/j.exphem.2023.08.008  0.341
2023 Chavez JS, Rabe JL, Niño KE, Wells HH, Gessner RL, Mills TS, Hernandez G, Pietras EM. PU.1 is required to restrain myelopoiesis during chronic inflammatory stress. Frontiers in Cell and Developmental Biology. 11: 1204160. PMID 37497478 DOI: 10.3389/fcell.2023.1204160  0.366
2023 Nash MJ, Dobrinskikh E, Soderborg TK, Janssen RC, Takahashi DL, Dean TA, Varlamov O, Hennebold JD, Gannon M, Aagaard KM, McCurdy CE, Kievit P, Bergman BC, Jones KL, Pietras EM, et al. Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring. Cell Reports. 42: 112393. PMID 37058409 DOI: 10.1016/j.celrep.2023.112393  0.304
2023 Mitchell CA, Verovskaya EV, Calero-Nieto FJ, Olson OC, Swann JW, Wang X, Hérault A, Dellorusso PV, Zhang SY, Svendsen AF, Pietras EM, Bakker ST, Ho TT, Göttgens B, Passegué E. Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing. Nature Cell Biology. PMID 36650381 DOI: 10.1038/s41556-022-01053-0  0.756
2022 Zhou C, Uluisik R, Rowley JW, David C, Jones CL, Scharer CD, Noetzli L, Fisher MH, Kirkpatrick GD, Bark K, Boss JM, Henry CJ, Pietras EM, Paola JD, Porter CC. Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors. Experimental Hematology. PMID 35803545 DOI: 10.1016/j.exphem.2022.06.002  0.31
2022 Patel SB, Pietras EM. B cells regulate hematopoietic stem cells via cholinergic signaling. Nature Immunology. 23: 476-478. PMID 35347284 DOI: 10.1038/s41590-022-01172-8  0.339
2022 Chavez JS, Rabe JL, Hernandez G, Mills TS, Niño KE, Davizon-Castillo P, Pietras EM. PU.1 Expression Defines Distinct Functional Activities in the Phenotypic HSC Compartment of a Murine Inflammatory Stress Model. Cells. 11. PMID 35203330 DOI: 10.3390/cells11040680  0.339
2022 Ahmed N, Etzrodt M, Dettinger P, Kull T, Loeffler D, Hoppe PS, Chavez JS, Zhang Y, Camargo Ortega G, Hilsenbeck O, Nakajima H, Pietras EM, Schroeder T. Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation. The Journal of Experimental Medicine. 219. PMID 34817548 DOI: 10.1084/jem.20202490  0.355
2021 Majumdar D, Pietras EM, Pawar SA. Analysis of Radiation-Induced Changes in Cell Cycle and DNA Damage of Murine Hematopoietic Stem Cells by Multi-Color Flow Cytometry. Current Protocols. 1: e216. PMID 34399037 DOI: 10.1002/cpz1.216  0.342
2021 Caiado F, Pietras EM, Manz MG. Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection. The Journal of Experimental Medicine. 218. PMID 34129016 DOI: 10.1084/jem.20201541  0.366
2021 Higa KC, Goodspeed A, Chavez JS, De Dominici M, Danis E, Zaberezhnyy V, Rabe JL, Tenen DG, Pietras EM, DeGregori J. Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors. The Journal of Experimental Medicine. 218. PMID 33914855 DOI: 10.1084/jem.20200560  0.323
2021 Chavez JS, Rabe JL, Loeffler D, Higa KC, Hernandez G, Mills TS, Ahmed N, Gessner RL, Ke Z, Idler BM, Niño KE, Kim H, Myers JR, Stevens BM, Davizon-Castillo P, ... ... Pietras EM, et al. PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress. The Journal of Experimental Medicine. 218. PMID 33857288 DOI: 10.1084/jem.20201169  0.372
2020 Fisher MH, Kirkpatrick GD, Stevens BM, Jones CL, Callaghan MU, Rajpurkar M, Fulbright J, Cooper MA, Rowley J, Porter CC, Gutierrez-Hartmann A, Jones K, Jordan CT, Pietras EM, Di Paola J. ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes. Jci Insight. PMID 32841218 DOI: 10.1172/Jci.Insight.140332  0.328
2020 Wang Y, Sano S, Yura Y, Ke Z, Sano M, Oshima K, Ogawa H, Horitani K, Min KD, Miura-Yura E, Kour A, Evans MA, Zuriaga MA, Hirschi KK, Fuster JJ, ... Pietras EM, et al. Tet2-mediated clonal hematopoiesis in non-conditioned mice accelerates age-associated cardiac dysfunction. Jci Insight. PMID 32154790 DOI: 10.1172/Jci.Insight.135204  0.453
2020 Kang YA, Pietras EM, Passegué E. Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia. The Journal of Experimental Medicine. 217. PMID 31886826 DOI: 10.1084/Jem.20190787  0.764
2019 Rabe JL, Hernandez G, Chavez JS, Mills TS, Nerlov C, Pietras EM. CD34 and EPCR coordinately enrich functional murine hematopoietic stem cells under normal and inflammatory conditions. Experimental Hematology. PMID 31863798 DOI: 10.1016/J.Exphem.2019.12.003  0.399
2019 Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, ... ... Pietras E, et al. TNF-alpha driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood. PMID 31311815 DOI: 10.1182/Blood.2019000200  0.382
2019 Hemmati S, Sinclair T, Tong M, Bartholdy B, Okabe RO, Ames K, Ostrodka L, Haque T, Kaur I, Mills TS, Agarwal A, Pietras EM, Zhao JJ, Roberts TM, Gritsman K. PI3 kinase alpha and delta promote hematopoietic stem cell activation. Jci Insight. 5. PMID 31120863 DOI: 10.1172/Jci.Insight.125832  0.478
2019 Hernandez G, Mills TS, Rabe JL, Chavez JS, Kuldanek S, Kirkpatrick G, Noetzli L, Jubair WK, Zanche M, Meyers JR, Stevens BM, Fleenor CJ, Adane B, Dinarello CA, Ashton J, ... ... Pietras EM, et al. Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis. Haematologica. PMID 31101752 DOI: 10.3324/Haematol.2018.197210  0.443
2019 Fisher MH, Kirkpatrick G, Jones CL, Stevens BM, Callaghan M, Pietras E, Jones KL, Porter CC, Di Paola J. Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes Blood. 134: 2316-2316. DOI: 10.1182/Blood-2019-132032  0.341
2019 Chavez J, Rabe JL, Higa K, Loeffler D, Nouraiz A, Mills T, Idler BM, Stevens BM, Fleenor C, Nerlov C, Nakajima H, Hagman J, Schroeder T, Kim HM, Jordan CT, ... ... Pietras E, et al. PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation Blood. 134: 822-822. DOI: 10.1182/Blood-2019-129300  0.486
2019 Pietras E, Rabe J, Chavez J, Higa K, Loeffler D, Mills T, Nerlov C, Schroeder T, DeGregori J. INTERLEUKIN-1 RESTRICTS HSC PROLIFERATION VIA A PU.1-DEPENDENT MECHANISM Experimental Hematology. 76: S82. DOI: 10.1016/J.Exphem.2019.06.420  0.451
2018 Chavez JS, Pietras EM. Hematopoietic Stem Cells Rock Around The Clock: Circadian Fate Control via TNF/ROS Signals. Cell Stem Cell. 23: 459-460. PMID 30290172 DOI: 10.1016/J.Stem.2018.09.002  0.496
2018 Fleenor CJ, Arends T, Lei H, Åhsberg J, Okuyama K, Kuruvilla J, Cristobal S, Rabe JL, Pandey A, Danhorn T, Straign D, Espinosa JM, Warming S, Pietras EM, Sigvardsson M, et al. Zinc Finger Protein 521 regulates early hematopoiesis through cell extrinsic mechanisms in the bone marrow microenvironment. Molecular and Cellular Biology. PMID 29915154 DOI: 10.1128/Mcb.00603-17  0.471
2018 Pietras EM. Ezh2 spares KitL from the cutter. Blood. 131: 2180-2181. PMID 29773542 DOI: 10.1182/Blood-2018-04-841890  0.426
2018 Jalbert E, Pietras EM. Analysis of Murine Hematopoietic Stem Cell Proliferation During Inflammation. Methods in Molecular Biology (Clifton, N.J.). 1686: 183-200. PMID 29030822 DOI: 10.1007/978-1-4939-7371-2_14  0.457
2018 NASH MJ, SODERBORG TK, JANSSEN RC, PIETRAS EM, FRIEDMAN JE. Maternal High-Fat Diet Persistently Alters Bone Marrow Immune Cell Proportions and Function in a Nonhuman Primate Model Diabetes. 67: 222-OR. DOI: 10.2337/Db18-222-Or  0.394
2018 Mills T, Hernandez G, Rabe JL, Kuldanek S, Chavez J, Kirkpatrick G, Noetzli L, Jubair W, Zanche M, Myers JR, Stevens BM, Fleenor C, Adane B, Ashton JM, Jordan CT, ... ... Pietras E, et al. Rheumatoid Arthritis Causes Hematopoietic Stem Cell Reprogramming to Maintain Functionality Blood. 132: 2573-2573. DOI: 10.1182/Blood-2018-99-120272  0.48
2018 Majumdar D, Pietras E, Stumhofer J, Pawar SA. Investigating the Role of C/Ebpδ-Deficiency in Radiation-Induced Bone Marrow Failure Blood. 132: 5103-5103. DOI: 10.1182/Blood-2018-99-119671  0.43
2018 Pietras E, Rabe J, Higa K, Chavez J, Mills T, Nemkov T, Nerlov C, Dinarello C, D'Alessandro A, DeGregori J. IL-1 Drives Clonal Hematopoiesis via Selective Induction of Growth Arrest in Normal HSC Experimental Hematology. 64: S93. DOI: 10.1016/J.Exphem.2018.06.119  0.324
2018 Verovskaya E, Calero-Nieto F, Reynaud D, Zhang SY, Herault A, Bakker S, Pietras E, Svendsen AF, Wang X, Kinston S, Ho T, Göttgens B, Passegue E. Inflammatory Changes in the Bone Marrow Microenvironment Drive Both Niche and Blood System Remodeling during Aging Experimental Hematology. 64: S43-S44. DOI: 10.1016/J.Exphem.2018.06.048  0.756
2017 Pietras EM. Inflammation: a key regulator of hematopoietic stem cell fate in health and disease. Blood. PMID 28874349 DOI: 10.1182/Blood-2017-06-780882  0.518
2017 Pietras EM. The importance of tying up loose (DNA) ends. Blood. 129: 2457-2458. PMID 28473409 DOI: 10.1182/Blood-2017-03-773184  0.406
2017 Hérault A, Binnewies M, Leong S, Calero-Nieto FJ, Zhang SY, Kang YA, Wang X, Pietras EM, Chu SH, Barry-Holson K, Armstrong S, Göttgens B, Passegué E. Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature. PMID 28355185 DOI: 10.1038/Nature21693  0.808
2017 Pietras E, Hernandez G, Kuldanek S, Jennifer R, Kirkpatrick G, Noetzli L, Acharya S, Adane B, Jordan C, DiPaola J, Holers M, Banda N. Altered HSC fate underlies aberrant blood phenotypes in rheumatoid arthritis Experimental Hematology. 53: S71. DOI: 10.1016/J.Exphem.2017.06.143  0.347
2016 Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CP, Techner JM, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nature Cell Biology. PMID 27111842 DOI: 10.1038/Ncb3346  0.721
2016 Davizon-Castillo P, Ashworth K, Higa K, Hernandez G, Acharya S, Campbell RA, Rondina M, Collins CB, Donato A, Lesniewski L, DeGregori J, Holer M, Banda N, Di Paola J, Pietras EM. Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging Blood. 128: 3747-3747. DOI: 10.1182/Blood.V128.22.3747.3747  0.397
2016 Jones CL, Kirkpatrick G, Fleenor C, Seth W, Noetzli LJ, Fosmire S, Baturin D, Liang X, Hernandez G, Pietras EM, Jordan CT, Rowley JW, Di Paola J, Hagman JR, Porter CC. ETV6 Regulates Pax5 Expression in Early B Cell Development Blood. 128: 2655-2655. DOI: 10.1182/Blood.V128.22.2655.2655  0.329
2016 Kang Y, Reynaud D, Pietras E, Passegué E. Myeloid-biased multipotent progenitor expansion by deregulated notch and WNT signaling drives myeloid malignancy Experimental Hematology. 44: S83. DOI: 10.1016/J.Exphem.2016.06.167  0.784
2016 Herault A, Binnewies M, Leong S, Calero F, Zhang SY, Pietras E, Chu H, Barry-Holson K, Armstrong S, Göttgens B, Passegue E. Myeloid progenitor cluster formation drives regenerative and leukemic myelopoiesis Experimental Hematology. 44: S79-S80. DOI: 10.1016/J.Exphem.2016.06.157  0.765
2016 Verovskaya E, Reynaud D, Bakker S, Zhang SY, Ho T, Pietras E, Passegué E. Remodeling of the multipotent progenitor (MPP) pool directly contributes to blood aging Experimental Hematology. 44: S54. DOI: 10.1016/J.Exphem.2016.06.079  0.756
2016 Pietras E, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk L, Zhang S, Lakshminarasimhan R, Chin CP, Techner J, Will B, Nerlov C, Steidl U, Manz M, Schroeder T, Passegué E. The PRO-inflammatory cytokine interleukin-1 is a key regulator of hematopoietic Stem cell fate and function Experimental Hematology. 44: S49. DOI: 10.1016/J.Exphem.2016.06.066  0.698
2015 Pietras EM, Reynaud D, Kang YA, Carlin D, Calero-Nieto FJ, Leavitt AD, Stuart JM, Göttgens B, Passegué E. Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions. Cell Stem Cell. 17: 35-46. PMID 26095048 DOI: 10.1016/J.Stem.2015.05.003  0.823
2015 Pietras EM, Mirantes-Barbeito C, Fong S, Loffler D, Kovtonyuk LV, Lakshminarashimhan R, Chin CP, Techner J, Will B, Nerlov C, Steidl U, Manz M, Schroeder T, Passegue E. Interleukin-1 Drives Precocious Myeloid Differentiation of Hematopoietic Stem Cells at the Expense of Self-Renewal Blood. 126: 778-778. DOI: 10.1182/Blood.V126.23.778.778  0.714
2015 Pietras EM, Reynaud D, Kang YA, Carlin D, Calero-Nieto FJ, Leavitt AD, Stuart JA, Göttgens B, Passegué E. Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions Cell Stem Cell. 17: 35-46. DOI: 10.1016/j.stem.2015.05.003  0.796
2014 Mirantes C, Passegué E, Pietras EM. Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis. Experimental Cell Research. 329: 248-54. PMID 25149680 DOI: 10.1016/J.Yexcr.2014.08.017  0.715
2014 Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, Méndez J, Morrison CG, Passegué E. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 512: 198-202. PMID 25079315 DOI: 10.1038/Nature13619  0.767
2014 Pietras EM, Lakshminarasimhan R, Techner JM, Fong S, Flach J, Binnewies M, Passegué E. Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons. The Journal of Experimental Medicine. 211: 245-62. PMID 24493802 DOI: 10.1084/Jem.20131043  0.787
2013 Pietras EM, Passegué E. Linking HSCs to their youth. Nature Cell Biology. 15: 885-7. PMID 23907190 DOI: 10.1038/Ncb2817  0.645
2013 Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell. 13: 285-99. PMID 23850243 DOI: 10.1016/J.Stem.2013.06.009  0.799
2013 Pietras EM, Passegué E. Erratum: Linking HSCs to their youth Nature Cell Biology. 15: 1131-1131. DOI: 10.1038/Ncb2841  0.6
2013 Pietras EM, Fong S, Löffler D, Lakshminarasimhan R, Techner J, Schroeder T, Passegué E. 198 Cytokine. 63: 290. DOI: 10.1016/J.Cyto.2013.06.201  0.725
2011 Pietras EM, Warr MR, Passegué E. Cell cycle regulation in hematopoietic stem cells. The Journal of Cell Biology. 195: 709-20. PMID 22123859 DOI: 10.1084/Jem20813Oia34  0.82
2011 Reynaud D, Pietras E, Barry-Holson K, Mir A, Binnewies M, Jeanne M, Sala-Torra O, Radich JP, Passegué E. IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell. 20: 661-73. PMID 22094259 DOI: 10.1016/J.Ccr.2011.10.012  0.811
2011 Pietras EM, Miller LS, Johnson CT, O'Connell RM, Dempsey PW, Cheng G. A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge. Cell Research. 21: 1068-79. PMID 21467996 DOI: 10.1038/Cr.2011.59  0.675
2011 Warr MR, Pietras EM, Passegué E. Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 681-701. PMID 21412991 DOI: 10.1002/Wsbm.145  0.822
2010 Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. The Journal of Clinical Investigation. 120: 1762-73. PMID 20364087 DOI: 10.1172/Jci40891  0.531
2010 Reynaud D, Pietras E, Jeanne M, Barry-Holson K, Passegue E. Leukemic Hierarchy and Systemic Factors Dictating Disease Evolution In Chronic Myelogenous Leukemia Blood. 116: 886-886. DOI: 10.1182/Blood.V116.21.886.886  0.816
2008 Pietras EM, Cheng G. A New TRADDition in intracellular antiviral signaling. Science Signaling. 1: pe36. PMID 18664658 DOI: 10.1126/Scisignal.130Pe36  0.493
2008 Pietras EM, Cheng G. New tricks for old NODs. Genome Biology. 9: 217. PMID 18466630 DOI: 10.1186/Gb-2008-9-4-217  0.5
2008 Oganesyan G, Saha SK, Pietras EM, Guo B, Miyahira AK, Zarnegar B, Cheng G. IRF3-dependent type I interferon response in B cells regulates CpG-mediated antibody production. The Journal of Biological Chemistry. 283: 802-8. PMID 17925397 DOI: 10.1074/Jbc.M704755200  0.769
2008 Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL. Inflammasome-mediated production of IL-1β is required for neutrophil recruitment against Staphylococcus aureus in vivo (Journal of Immunolgy (2007) 179 (6933-6942)) Journal of Immunology. 180: 665.  0.545
2007 Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, O'Rourke KM, Eby M, Pietras E, Cheng G, Bazan JF, Zhang Z, Arnott D, Dixit VM. DUBA: A deubiquitinase that regulates type I interferon production Science. 318: 1628-1632. PMID 17991829 DOI: 10.1126/Science.1145918  0.502
2007 Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. Journal of Immunology (Baltimore, Md. : 1950). 179: 6933-42. PMID 17982084 DOI: 10.4049/Jimmunol.179.10.6933  0.677
2007 Pietras EM, Saha SK, Miller LS, Uricchio LH, O’Connell RM, Iwakura Y, Cheung AL, Modlin RL, Cheng G. 121 Role of Myeloid Differentiation Factor 88-dependent Cytokines in Activation of Host Defense Functions Against Bacterial Infection Cytokine. 39: 33. DOI: 10.1016/J.Cyto.2007.07.126  0.503
2006 Pietras EM, Saha SK, Cheng G. The interferon response to bacterial and viral infections. Journal of Endotoxin Research. 12: 246-50. PMID 16953977 DOI: 10.1177/09680519060120040601  0.631
2006 Saha SK, Pietras EM, He JQ, Kang JR, Liu SY, Oganesyan G, Shahangian A, Zarnegar B, Shiba TL, Wang Y, Cheng G. Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. The Embo Journal. 25: 3257-63. PMID 16858409 DOI: 10.1038/Sj.Emboj.7601220  0.74
2006 Miller LS, O'Connell RM, Gutierrez MA, Pietras EM, Shahangian A, Gross CE, Thirumala A, Cheung AL, Cheng G, Modlin RL. MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus. Immunity. 24: 79-91. PMID 16413925 DOI: 10.1016/J.Immuni.2005.11.011  0.78
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