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Michelle E. Kimple, Ph.D. - Publications

Affiliations: 
2003 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biochemistry, General Biophysics, Molecular Biology
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ. Pancreatic β cells from Mice Offset Age-Associated Mitochondrial Deficiency with Reduced KATP Channel Activity. Diabetes. PMID 27284112 DOI: 10.2337/Db16-0432  0.36
2016 Brill AL, Wisinski JA, Cadena MT, Thompson MF, Fenske RJ, Brar HK, Schaid MD, Pasker RL, Kimple ME. Synergy between Gαz deficiency and GLP-1 analog treatment in preserving functional beta-cell mass in experimental diabetes. Molecular Endocrinology (Baltimore, Md.). me20151164. PMID 27049466 DOI: 10.1210/Me.2015-1164  0.36
2016 Wisinski JA, Kimple ME. Platelet Dysfunction in Type 1 Diabetes: Stressing the Thromboxanes. Diabetes. 65: 349-51. PMID 26798121 DOI: 10.2337/dbi15-0032  0.36
2016 Arriola Apelo SI, Neuman JC, Baar EL, Syed FA, Cummings NE, Brar HK, Pumper CP, Kimple ME, Lamming DW. Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system. Aging Cell. 15: 28-38. PMID 26463117 DOI: 10.1111/acel.12405  0.36
2015 Truchan NA, Brar HK, Gallagher SJ, Neuman JC, Kimple ME. A single-islet microplate assay to measure mouse and human islet insulin secretion. Islets. 0. PMID 26452321 DOI: 10.1080/19382014.2015.1076607  0.36
2015 Pierre JF, Neuman JC, Brill AL, Brar HK, Thompson MF, Cadena MT, Connors KM, Busch RA, Heneghan AF, Cham CM, Jones EK, Kibbe CR, Davis DB, Groblewski GE, Kudsk KA, ... Kimple ME, et al. The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition. American Journal of Physiology. Gastrointestinal and Liver Physiology. 309: G431-42. PMID 26185331 DOI: 10.1152/Ajpgi.00072.2015  0.36
2015 Oropeza D, Jouvet N, Budry L, Campbell JE, Bouyakdan K, Lacombe J, Perron G, Bergeron V, Neuman JC, Brar HK, Fenske RJ, Meunier C, Sczelecki S, Kimple ME, Drucker DJ, et al. Phenotypic characterization of MIP-CreERT1Lphi mice with transgene-driven islet expression of human growth hormone. Diabetes. PMID 26153246 DOI: 10.2337/db15-0272  0.36
2015 Linnemann AK, Neuman JC, Battiola TJ, Wisinski JA, Kimple ME, Davis DB. Glucagon-like peptide-1 Regulates Cholecystokinin Production in β-cells to Protect from Apoptosis. Molecular Endocrinology (Baltimore, Md.). me20151030. PMID 25984632 DOI: 10.1210/me.2015-1030  0.36
2015 Busch RA, Heneghan AF, Pierre JF, Neuman JC, Reimer CA, Wang X, Kimple ME, Kudsk KA. Bombesin Preserves Goblet Cell Resistin-like Molecule β During Parenteral Nutrition but Not Other Goblet Cell Products. Jpen. Journal of Parenteral and Enteral Nutrition. PMID 25934045 DOI: 10.1177/0148607115585353  0.36
2014 Neuman JC, Truchan NA, Joseph JW, Kimple ME. A method for mouse pancreatic islet isolation and intracellular cAMP determination. Journal of Visualized Experiments : Jove. e50374. PMID 24998772 DOI: 10.3791/50374  0.36
2014 Kimple ME, Neuman JC, Linnemann AK, Casey PJ. Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes. Experimental & Molecular Medicine. 46: e102. PMID 24946790 DOI: 10.1038/emm.2014.40  0.36
2013 Kimple ME, Brill AL, Pasker RL. Overview of affinity tags for protein purification. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 73: Unit 9.9. PMID 24510596 DOI: 10.1002/0471140864.ps0909s73  0.36
2013 Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB. Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line. American Journal of Physiology. Endocrinology and Metabolism. 305: E600-10. PMID 23860123 DOI: 10.1152/ajpendo.00147.2013  0.36
2012 Kimple ME, Moss JB, Brar HK, Rosa TC, Truchan NA, Pasker RL, Newgard CB, Casey PJ. Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass. The Journal of Biological Chemistry. 287: 20344-55. PMID 22457354 DOI: 10.1074/jbc.M112.359745  0.36
2010 Kelly P, Bailey CL, Fueger PT, Newgard CB, Casey PJ, Kimple ME. Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferation. The Journal of Biological Chemistry. 285: 15777-85. PMID 20339002 DOI: 10.1074/jbc.M109.069112  0.36
2010 Kimple ME, Hultman RC, Casey PJ. Signaling through Gz Handbook of Cell Signaling, 2/E. 2: 1649-1653. DOI: 10.1016/B978-0-12-374145-5.00202-3  0.36
2008 Kimple ME, Joseph JW, Bailey CL, Fueger PT, Hendry IA, Newgard CB, Casey PJ. Galphaz negatively regulates insulin secretion and glucose clearance. The Journal of Biological Chemistry. 283: 4560-7. PMID 18096703 DOI: 10.1074/jbc.M706481200  0.36
2005 Kimple ME, Nixon AB, Kelly P, Bailey CL, Young KH, Fields TA, Casey PJ. A role for G(z) in pancreatic islet beta-cell biology. The Journal of Biological Chemistry. 280: 31708-13. PMID 16157560 DOI: 10.1074/jbc.M506700200  0.36
2005 Pagliarini DJ, Wiley SE, Kimple ME, Dixon JR, Kelly P, Worby CA, Casey PJ, Dixon JE. Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Molecular Cell. 19: 197-207. PMID 16039589 DOI: 10.1016/J.Molcel.2005.06.008  0.36
2004 Kimple ME, Sondek J. Overview of affinity tags for protein purification. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 9.9. PMID 18429272 DOI: 10.1002/0471140864.ps0909s36  0.36
2002 Kimple ME, Sondek J. Affinity tag for protein purification and detection based on the disulfide-linked complex of InaD and NorpA. Biotechniques. 33: 578, 580, 584-8 pass. PMID 12238768  0.36
2002 Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP. Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits. Nature. 416: 878-81. PMID 11976690 DOI: 10.1038/416878a  0.36
2001 Kimple ME, Siderovski DP, Sondek J. Functional relevance of the disulfide-linked complex of the N-terminal PDZ domain of InaD with NorpA Embo Journal. 20: 4414-4422. PMID 11500369 DOI: 10.1093/emboj/20.16.4414  0.36
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