Lawrence A. Quilliam - Publications

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry, Cell Biology

65/94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 7. PMID 29360039 DOI: 10.7554/Elife.32586  0.435
2016 Sana ME, Quilliam LA, Spitaleri A, Pezzoli L, Marchetti D, Lodrini C, Candiago E, Lincesso AR, Ferrazzi P, Iascone M. A Novel HRAS Mutation Independently Contributes to Left Ventricular Hypertrophy in a Family with a Known MYH7 Mutation. Plos One. 11: e0168501. PMID 28002430 DOI: 10.1371/Journal.Pone.0168501  0.319
2015 Chrzanowska-Wodnicka M, White GC, Quilliam LA, Whitehead KJ. Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature. Plos One. 10: e0145689. PMID 26714318 DOI: 10.1371/Journal.Pone.0145689  0.318
2015 Birukova AA, Meng F, Tian Y, Meliton A, Sarich N, Quilliam LA, Birukov KG. Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1. Biochimica Et Biophysica Acta. 1852: 778-91. PMID 25545047 DOI: 10.1016/J.Bbadis.2014.12.016  0.308
2014 Sayyah J, Bartakova A, Nogal N, Quilliam LA, Stupack DG, Brown JH. The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth. The Journal of Biological Chemistry. 289: 17689-98. PMID 24790104 DOI: 10.1074/Jbc.M113.536227  0.529
2013 Wittchen ES, Nishimura E, McCloskey M, Wang H, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo. Plos One. 8: e73070. PMID 24039860 DOI: 10.1371/Journal.Pone.0073070  0.388
2013 Babcock JT, Nguyen HB, He Y, Hendricks JW, Wek RC, Quilliam LA. Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response. The Journal of Biological Chemistry. 288: 15687-98. PMID 23612979 DOI: 10.1074/Jbc.M112.431056  0.767
2013 Schmid MC, Franco I, Kang SW, Hirsch E, Quilliam LA, Varner JA. PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth. Plos One. 8: e60226. PMID 23565202 DOI: 10.1371/Journal.Pone.0060226  0.445
2013 Nguyen HB, Babcock JT, Wells CD, Quilliam LA. LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Oncogene. 32: 4100-9. PMID 23027127 DOI: 10.1038/Onc.2012.431  0.786
2012 Crotzer VL, Matute JD, Arias AA, Zhao H, Quilliam LA, Dinauer MC, Blum JS. Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 3800-4. PMID 22984083 DOI: 10.4049/Jimmunol.1103080  0.303
2012 Siroky BJ, Yin H, Babcock JT, Lu L, Hellmann AR, Dixon BP, Quilliam LA, Bissler JJ. Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress. American Journal of Physiology. Renal Physiology. 303: F831-44. PMID 22791333 DOI: 10.1152/Ajprenal.00441.2011  0.758
2012 Jeyaraj SC, Unger NT, Eid AH, Mitra S, Paul El-Dahdah N, Quilliam LA, Flavahan NA, Chotani MA. Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 303: C499-511. PMID 22621783 DOI: 10.1152/Ajpcell.00461.2011  0.428
2012 Castro AF, Campos T, Babcock JT, Armijo ME, Martínez-Conde A, Pincheira R, Quilliam LA. M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells. Journal of Cellular Biochemistry. 113: 1253-64. PMID 22121046 DOI: 10.1002/Jcb.23458  0.761
2012 Nguyen HB, Babcock JT, Wells CD, Quilliam LA. Abstract LB-29: LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-29  0.785
2012 Babcock JT, Nguen HB, He Y, Wek RC, Quilliam LA. Abstract LB-247: mTORC1 enhances bortezomib-induced death in TSC-null cells by a c-MYC-dependent induction of the unfolded protein response Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-247  0.779
2011 Bai Y, Luo Y, Liu S, Zhang L, Shen K, Dong Y, Walls CD, Quilliam LA, Wells CD, Cao Y, Zhang ZY. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. The Journal of Biological Chemistry. 286: 42316-24. PMID 22009749 DOI: 10.1074/Jbc.M111.286302  0.394
2011 Kepner EM, Yoder SM, Oh E, Kalwat MA, Wang Z, Quilliam LA, Thurmond DC. Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 301: E1072-80. PMID 21828338 DOI: 10.1152/Ajpendo.00312.2011  0.374
2011 Babcock JT, Quilliam LA. Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin. Current Drug Targets. 12: 1223-31. PMID 21561413 DOI: 10.2174/138945011795906589  0.759
2010 Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam LA, Chrzanowska-Wodnicka M, White GC, Malarkannan S. Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. The Journal of Experimental Medicine. 207: 1923-38. PMID 20733035 DOI: 10.1084/Jem.20100040  0.328
2010 Panchatcharam M, Miriyala S, Yang F, Leitges M, Chrzanowska-Wodnicka M, Quilliam LA, Anaya P, Morris AJ, Smyth SS. Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. The International Journal of Biochemistry & Cell Biology. 42: 965-74. PMID 20184965 DOI: 10.1016/J.Biocel.2010.02.009  0.367
2008 Asuri S, Yan J, Paranavitana NC, Quilliam LA. E-cadherin dis-engagement activates the Rap1 GTPase. Journal of Cellular Biochemistry. 105: 1027-37. PMID 18767072 DOI: 10.1002/Jcb.21902  0.74
2008 Yan J, Li F, Ingram DA, Quilliam LA. Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions. Molecular and Cellular Biology. 28: 5803-10. PMID 18625726 DOI: 10.1128/Mcb.00393-08  0.649
2007 Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Munugulavadla V, Kapur R, Chen H, Shou W, Stone JC, ... ... Quilliam LA, et al. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. Journal of Immunology (Baltimore, Md. : 1950). 179: 8322-31. PMID 18056377 DOI: 10.4049/Jimmunol.179.12.8322  0.606
2007 Quilliam LA. New insights into the mechanisms of SOS activation. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe67. PMID 18042941 DOI: 10.1126/Stke.4142007Pe67  0.429
2007 Hong J, Doebele RC, Lingen MW, Quilliam LA, Tang WJ, Rosner MR. Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1. The Journal of Biological Chemistry. 282: 19781-7. PMID 17491018 DOI: 10.1074/Jbc.M700128200  0.311
2006 Quilliam LA. Specificity and expression of RalGPS as RalGEFs. Methods in Enzymology. 407: 108-14. PMID 16757318 DOI: 10.1016/S0076-6879(05)07010-2  0.37
2006 Felekkis K, Quilliam LA, Lerner A. Characterization of AND-34 function and signaling. Methods in Enzymology. 407: 55-63. PMID 16757314 DOI: 10.1016/S0076-6879(05)07006-0  0.393
2006 Li Y, Asuri S, Rebhun JF, Castro AF, Paranavitana NC, Quilliam LA. The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane. The Journal of Biological Chemistry. 281: 2506-14. PMID 16316996 DOI: 10.1074/Jbc.M508165200  0.743
2005 Castro AF, Rebhun JF, Quilliam LA. Measuring Ras-family GTP levels in vivo--running hot and cold. Methods (San Diego, Calif.). 37: 190-6. PMID 16289967 DOI: 10.1016/J.Ymeth.2005.05.015  0.398
2005 Felekkis KN, Narsimhan RP, Near R, Castro AF, Zheng Y, Quilliam LA, Lerner A. AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner. Molecular Cancer Research : McR. 3: 32-41. PMID 15671247  0.409
2004 Arthur WT, Quilliam LA, Cooper JA. Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. The Journal of Cell Biology. 167: 111-22. PMID 15479739 DOI: 10.1083/Jcb.200404068  0.497
2003 Castro AF, Rebhun JF, Clark GJ, Quilliam LA. Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner. The Journal of Biological Chemistry. 278: 32493-6. PMID 12842888 DOI: 10.1074/Jbc.C300226200  0.493
2003 Zheng Y, Quilliam LA. Activation of the Ras superfamily of small GTPases. Workshop on exchange factors. Embo Reports. 4: 463-8. PMID 12717452 DOI: 10.1038/Sj.Embor.Embor831  0.457
2002 Gu Y, Byrne MC, Paranavitana NC, Aronow B, Siefring JE, D'Souza M, Horton HF, Quilliam LA, Williams DA. Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells. Molecular and Cellular Biology. 22: 7645-57. PMID 12370311 DOI: 10.1128/Mcb.22.21.7645-7657.2002  0.471
2002 Quilliam LA, Rebhun JF, Castro AF. A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases. Progress in Nucleic Acid Research and Molecular Biology. 71: 391-444. PMID 12102558 DOI: 10.1016/S0079-6603(02)71047-7  0.439
2002 Reuther GW, Lambert QT, Rebhun JF, Caligiuri MA, Quilliam LA, Der CJ. RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia. The Journal of Biological Chemistry. 277: 30508-14. PMID 11880369 DOI: 10.1074/Jbc.M111330200  0.377
2002 Mei FC, Qiao J, Tsygankova OM, Meinkoth JL, Quilliam LA, Cheng X. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation. The Journal of Biological Chemistry. 277: 11497-504. PMID 11801596 DOI: 10.1074/Jbc.M110856200  0.358
2001 Zong H, Kaibuchi K, Quilliam LA. The insert region of RhoA is essential for Rho kinase activation and cellular transformation. Molecular and Cellular Biology. 21: 5287-98. PMID 11463812 DOI: 10.1128/Mcb.21.16.5287-5298.2001  0.443
2001 Quilliam LA, Rebhun JF, Zong H, Castro AF. Analyses of M-Ras/R-Ras3 signaling and biology. Methods in Enzymology. 333: 187-202. PMID 11400336 DOI: 10.1016/S0076-6879(01)33056-2  0.385
2001 Tsygankova OM, Saavedra A, Rebhun JF, Quilliam LA, Meinkoth JL. Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A. Molecular and Cellular Biology. 21: 1921-9. PMID 11238928 DOI: 10.1128/Mcb.21.6.1921-1929.2001  0.486
2000 Rebhun JF, Castro AF, Quilliam LA. Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction. The Journal of Biological Chemistry. 275: 34901-8. PMID 10934204 DOI: 10.1074/Jbc.M005327200  0.422
2000 Rebhun JF, Chen H, Quilliam LA. Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral. The Journal of Biological Chemistry. 275: 13406-10. PMID 10747847 DOI: 10.1074/Jbc.C000085200  0.4
2000 Sood R, Porter AC, Ma K, Quilliam LA, Wek RC. Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress. The Biochemical Journal. 346: 281-93. PMID 10677345 DOI: 10.1042/0264-6021:3460281  0.393
1999 Quilliam LA, Castro AF, Rogers-Graham KS, Martin CB, Der CJ, Bi C. M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6. The Journal of Biological Chemistry. 274: 23850-7. PMID 10446149 DOI: 10.1074/Jbc.274.34.23850  0.325
1999 Braverman LE, Quilliam LA. Identification of Grb4/Nckβ, a Src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck Journal of Biological Chemistry. 274: 5542-5549. PMID 10026169 DOI: 10.1074/Jbc.274.9.5542  0.403
1999 Zong H, Raman N, Mickelson-Young LA, Atkinson SJ, Quilliam LA. Loop 6 of RhoA confers specificity for effector binding, stress fiber formation, and cellular transformation Journal of Biological Chemistry. 274: 4551-4560. PMID 9988689 DOI: 10.1074/Jbc.274.8.4551  0.399
1997 Lander HM, Hajjar DP, Hempstead BL, Mirza UA, Chait BT, Campbell S, Quilliam LA. A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. The Journal of Biological Chemistry. 272: 4323-6. PMID 9020151 DOI: 10.1074/Jbc.272.7.4323  0.386
1997 Huff SY, Quilliam LA, Cox AD, Der CJ. R-Ras is regulated by activators and effectors distinct from those that control Ras function Oncogene. 14: 133-143. PMID 9010215 DOI: 10.1038/Sj.Onc.1200815  0.392
1996 Quilliam LA, Lambert QT, Mickelson-Young LA, Westwick JK, Sparks AB, Kay BK, Jenkins NA, Gilbert DJ, Copeland NG, Der CJ. Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling. The Journal of Biological Chemistry. 271: 28772-6. PMID 8910519 DOI: 10.1074/Jbc.271.46.28772  0.397
1996 Bokoch GM, Wang Y, Bohl BP, Sells MA, Quilliam LA, Knaus UG. Interaction of the Nck adapter protein with p21-activated kinase (PAK1) Journal of Biological Chemistry. 271: 25746-25749. PMID 8824201 DOI: 10.1074/Jbc.271.42.25746  0.378
1996 Lander HM, Milbank AJ, Tauras JM, Hajjar DP, Hempstead BL, Schwartz GD, Kraemer RT, Mirza UA, Chait BT, Burk SC, Quilliam LA. Redox regulation of cell signalling. Nature. 381: 380-1. PMID 8632794 DOI: 10.1038/381380A0  0.414
1996 Quilliam LA, Hisaka MM, Zhong S, Lowry A, Mosteller RD, Han J, Drugan JK, Broek D, Campbell SL, Der CJ. Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors. The Journal of Biological Chemistry. 271: 11076-82. PMID 8626650 DOI: 10.1074/Jbc.271.19.11076  0.391
1996 Song KS, Li S, Okamoto T, Quilliam LA, Sargiacomo M, Lisanti MP. Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains: Detergent-free purification of caveolae membranes Journal of Biological Chemistry. 271: 9690-9697. PMID 8621645 DOI: 10.1074/Jbc.271.16.9690  0.375
1996 Fridell YWC, Jin Y, Quilliam LA, Burchert A, Mccloskey P, Spizz G, Varnum B, Der C, Liu ET. Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase Molecular and Cellular Biology. 16: 135-145. PMID 8524290 DOI: 10.1128/Mcb.16.1.135  0.419
1995 Overbeck AF, Brtva TR, Cox AD, Graham SM, Huff SY, Khosravi-Far R, Quilliam LA, Solski PA, Der CJ. Guanine nucleotide exchange factors: activators of Ras superfamily proteins. Molecular Reproduction and Development. 42: 468-76. PMID 8607978 DOI: 10.1002/Mrd.1080420415  0.312
1995 Quilliam LA, Khosravi-Far R, Huff SY, Der CJ. Guanine nucleotide exchange factors: Activators of the Ras superfamily of proteins Bioessays. 17: 395-404. PMID 7786285 DOI: 10.1002/Bies.950170507  0.324
1994 Quilliam LA, Huff SY, Rabun KM, Wei W, Park W, Broek D, Der CJ. Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity. Proceedings of the National Academy of Sciences of the United States of America. 91: 8512-6. PMID 8078913 DOI: 10.1073/Pnas.91.18.8512  0.334
1994 Maly FE, Quilliam LA, Dorseuil O, Der CJ, Bokoch GM. Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes Journal of Biological Chemistry. 269: 18743-18746. PMID 8034626  0.315
1994 Scheele JS, Pilz RB, Quilliam LA, Boss GR. Identification of a ras-related protein in murine erythroleukemia cells that is a cAMP-dependent protein kinase substrate and is phosphorylated during chemically induced differentiation Journal of Biological Chemistry. 269: 18599-18606. PMID 8034608  0.34
1993 Clark GJ, Quilliam LA, Hisaka MM, Der CJ. Differential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein Proceedings of the National Academy of Sciences of the United States of America. 90: 4887-4891. PMID 8506332 DOI: 10.1073/Pnas.90.11.4887  0.314
1993 Pendergast AM, Quilliam LA, Cripe LD, Bassing CH, Dai Z, Li N, Batzer A, Rabun KM, Der CJ, Schlessinger J. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein. Cell. 75: 175-85. PMID 8402896  0.35
1991 Buss JE, Quilliam LA, Kato K, Casey PJ, Solski PA, Wong G, Clark R, McCormick F, Bokoch GM, Der CJ. The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein. Molecular and Cellular Biology. 11: 1523-30. PMID 1899909 DOI: 10.1128/Mcb.11.3.1523  0.319
1990 Quilliam LA, Der CJ, Brown JH. GTP-binding protein-stimulated phospholipase C and phospholipase D activities in ras-transformed NIH 3T3 fibroblasts Second Messengers and Phosphoproteins. 13: 59-67. PMID 2149569  0.333
1988 Brown JH, Orellana SA, Buss JE, Quilliam LA. Regulation of phosphoinositide hydrolysis by GTP-binding proteins, phorbol esters and botulinum toxin type D Advances in Experimental Medicine and Biology. 236: 229-237. PMID 2853564 DOI: 10.1007/978-1-4757-5971-6_18  0.366
1988 Quilliam LA, Brown JH, Buss JE. A 22 kDa ras-related G-protein is the substrate for an ADP-ribosyltransferase from Clostridium botulinum Febs Letters. 238: 22-26. PMID 2844595 DOI: 10.1016/0014-5793(88)80217-5  0.358
Low-probability matches (unlikely to be authored by this person)
1990 Quilliam LA, Der CJ, Clark R, O'Rourke EC, Zhang K, McCormick F, Bokoch GM. Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins. Molecular and Cellular Biology. 10: 2901-8. PMID 2160589 DOI: 10.1128/Mcb.10.6.2901  0.3
2009 Woolfrey KM, Srivastava DP, Photowala H, Yamashita M, Barbolina MV, Cahill ME, Xie Z, Jones KA, Quilliam LA, Prakriya M, Penzes P. Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines. Nature Neuroscience. 12: 1275-84. PMID 19734897 DOI: 10.1038/Nn.2386  0.296
1989 Quilliam LA, Dobson PRM, Brown BL. Regulation of GH3 pituitary tumour-cell adenylate cyclase activity by activators of protein kinase C Biochemical Journal. 262: 829-834. PMID 2480108  0.289
1995 Solski PA, Quilliam LA, Coats SG, Der CJ, Buss JE. Targeting proteins to membranes using signal sequences for lipid modification. Methods in Enzymology. 250: 435-54. PMID 7651170 DOI: 10.1016/0076-6879(95)50089-8  0.286
1995 Hauser CA, Westwick JK, Quilliam LA. Ras-mediated transcription activation: Analysis by transient cotransfection assays Methods in Enzymology. 255: 412-426. PMID 8524127 DOI: 10.1016/S0076-6879(95)55043-7  0.278
1991 Yatani A, Quilliam LA, Brown AM, Bokoch GM. Rap1A antagonizes the ability of ras and ras-gap to inhibit muscarinic K+ channels Journal of Biological Chemistry. 266: 22222-22226. PMID 1939245  0.277
2000 Reuther GW, Buss JE, Quilliam LA, Clark GJ, Der CJ. Analysis of function and regulation of proteins that mediate signal transduction by use of lipid-modified plasma membrane-targeting sequences Methods in Enzymology. 327: 331-350. PMID 11044995 DOI: 10.1016/S0076-6879(00)27288-1  0.276
2005 Wittchen ES, Worthylake RA, Kelly P, Casey PJ, Quilliam LA, Burridge K. Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function. The Journal of Biological Chemistry. 280: 11675-82. PMID 15661741 DOI: 10.1074/Jbc.M412595200  0.263
2003 Riggins RB, Quilliam LA, Bouton AH. Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3. The Journal of Biological Chemistry. 278: 28264-73. PMID 12740391 DOI: 10.1074/Jbc.M303535200  0.26
2002 Li S, Yamauchi A, Marchal CC, Molitoris JK, Quilliam LA, Dinauer MC. Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions. Journal of Immunology (Baltimore, Md. : 1950). 169: 5043-51. PMID 12391220 DOI: 10.4049/Jimmunol.169.9.5043  0.259
1996 Quilliam LA, Westwick JK, Der CJ, Lambert QT. Cloning and characterization of proteins that bind the sh3 domains of the nck adaptor protein Faseb Journal. 10.  0.255
1994 Quilliam LA, Kato K, Rabun KM, Hisaka MM, Huff SY, Campbell-Burk S, Der CJ. Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors Molecular and Cellular Biology. 14: 1113-1121. PMID 8289792 DOI: 10.1128/Mcb.14.2.1113  0.252
2016 Wang H, Han X, Bretz CA, Becker S, Gambhir D, Smith GW, Samulski RJ, Wittchen ES, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization. Molecular Therapy. Methods & Clinical Development. 3: 16056. PMID 27606349 DOI: 10.1038/mtm.2016.56  0.243
2014 Wang H, Jiang Y, Shi D, Quilliam LA, Chrzanowska-Wodnicka M, Wittchen ES, Li DY, Hartnett ME. Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 265-74. PMID 24043260 DOI: 10.1096/fj.13-240028  0.242
1995 Quilliam LA, Zhong S, Rabun KM, Carpenter JW, South TL, Der CJ, Campbell-Burk S. Biological and structural characterization of a Ras transforming mutation at the phenylalanine-156 residue, which is conserved in all members of the Ras superfamily Proceedings of the National Academy of Sciences of the United States of America. 92: 1272-1276. PMID 7877967 DOI: 10.1073/Pnas.92.5.1272  0.24
1989 Quilliam LA, Lacal JC, Bokoch GM. Identification of rho as a substrate for botulinum toxin C3-catalyzed ADP-ribosylation Febs Letters. 247: 221-226. PMID 2497029 DOI: 10.1016/0014-5793(89)81339-0  0.239
1991 Quilliam LA, Mueller H, Bohl BP, Prossnitz V, Sklar LA, Der CJ, Bokoch GM. Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils Journal of Immunology. 147: 1628-1635. PMID 1908879  0.236
1985 Quilliam LA, Dobson PRM, Brown BL. Phorbol ester-induced inhibition of vasoactive intestinal polypeptide-stimulated cyclic AMP accumulation in GH3 pituitary tumour cells Biochemical Society Transactions. 13: 786-787.  0.234
1991 Bokoch GM, Quilliam LA, Bohl BP, Jesaitis AJ, Quinn MT. Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A Science. 254: 1794-1796. PMID 1763330 DOI: 10.1126/Science.1763330  0.231
1985 Quilliam LA, Dobson PRM, Brown BL. Modulation of cyclic AMP accumulation in GH3 cells by a phorbol ester and thyroliberin Biochemical and Biophysical Research Communications. 129: 898-903. PMID 2409970 DOI: 10.1016/0006-291X(85)91976-X  0.231
2008 Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugulavadla V, Kapur R, Chen H, Shou W, Stone JC, Kaplan MH, ... ... Quilliam LA, et al. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins (Journal of Immunology (2007) 179 (8322-8331)) Journal of Immunology. 180: 3612.  0.207
1990 Bokoch GM, Quilliam LA. Guanine nucleotide binding properties of rap1 purified from human neutrophils Biochemical Journal. 267: 407-411. PMID 2110451 DOI: 10.1042/BJ2670407  0.206
2020 Kim O, Park EY, Kwon SY, Shin S, Emerson RE, Shin YH, DeMayo FJ, Lydon JP, Coffey DM, Hawkins SM, Quilliam LA, Cheon DJ, Fernández FM, Nephew KP, Karpf AR, et al. Targeting progesterone signaling prevents metastatic ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 33262282 DOI: 10.1073/pnas.2013595117  0.205
1994 Chuang TH, Xu X, Quilliam LA, Bokoch GM. SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism Biochemical Journal. 303: 761-767. PMID 7980444 DOI: 10.1042/Bj3030761  0.201
2007 Ming W, Li S, Billadeau DD, Quilliam LA, Dinauer MC. The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity. Molecular and Cellular Biology. 27: 312-23. PMID 17060455 DOI: 10.1128/Mcb.00985-06  0.194
1996 Sparks AB, Rider JE, Hoffman NG, Fowlkes DM, Quilliam LA, Kay BK. Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCγ, Crk, and Grb2 Proceedings of the National Academy of Sciences of the United States of America. 93: 1540-1544. PMID 8643668 DOI: 10.1073/Pnas.93.4.1540  0.137
1986 Quilliam LA, Baird JG, Dobson PRM, Brown BL. Guanosine 5'-O-(3-thiotriphosphate) and thyroliberin stimulate inositol phosphate production in GH3 cell homogenates Biochemical Society Transactions. 14: 685-686.  0.126
1994 Sparks AB, Quilliam LA, Thorn JM, Der CJ, Kay BK. Identification and characterization of Src SH3 ligands from phage-displayed random peptide libraries. The Journal of Biological Chemistry. 269: 23853-6. PMID 7929027  0.114
1995 Sparks AB, Adey NB, Quilliam LA, Thorn JM, Kay BK. Screening phage-displayed random peptide libraries for SH3 ligands. Methods in Enzymology. 255: 498-509. PMID 8524137 DOI: 10.1016/S0076-6879(95)55052-6  0.013
Hide low-probability matches.