Abraham M. Lenhoff - Publications

Affiliations: 
Department of Chemical Engineering University of Delaware, Newark, DE, United States 
Area:
Chemical Engineering

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Year Citation  Score
2023 Paul B, Furst EM, Lenhoff AM, Wagner NJ, Teixeira SCM. Combined Effects of Pressure and Ionic Strength on Protein-Protein Interactions: An Empirical Approach. Biomacromolecules. PMID 38117685 DOI: 10.1021/acs.biomac.3c01001  0.302
2023 Bhoyar S, Kumar V, Foster M, Xu X, Traylor SJ, Guo J, Lenhoff AM. Predictive mechanistic modeling of loading and elution in protein A chromatography. Journal of Chromatography. A. 1713: 464558. PMID 38096684 DOI: 10.1016/j.chroma.2023.464558  0.801
2023 Herman CE, Min L, Choe LH, Maurer RW, Xu X, Ghose S, Lee KH, Lenhoff AM. Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography. Journal of Chromatography. A. 1702: 464081. PMID 37244165 DOI: 10.1016/j.chroma.2023.464081  0.576
2023 Bhoyar S, Foster M, Oh YH, Xu X, Traylor SJ, Guo J, Ghose S, Lenhoff AM. Engineering protein A ligands to mitigate antibody loss during high-pH washes in protein A chromatography. Journal of Chromatography. A. 1696: 463962. PMID 37043977 DOI: 10.1016/j.chroma.2023.463962  0.801
2023 Herman CE, Min L, Choe LH, Maurer RW, Xu X, Ghose S, Lee KH, Lenhoff AM. Analytical characterization of host-cell-protein-rich aggregates in monoclonal antibody solutions. Biotechnology Progress. e3343. PMID 37020359 DOI: 10.1002/btpr.3343  0.57
2023 Altern SH, Welsh JP, Lyall JY, Kocot AJ, Burgess S, Kumar V, Williams C, Lenhoff AM, Cramer SM. Isotherm model discrimination for multimodal chromatography using mechanistic models derived from high-throughput batch isotherm data. Journal of Chromatography. A. 1693: 463878. PMID 36827799 DOI: 10.1016/j.chroma.2023.463878  0.333
2021 Herman CE, Xu X, Traylor SJ, Ghose S, Li ZJ, Lenhoff AM. Behavior of weakly adsorbing protein impurities in flow-through ion-exchange chromatography. Journal of Chromatography. A. 1664: 462788. PMID 34998025 DOI: 10.1016/j.chroma.2021.462788  0.824
2021 Kumar V, Leweke S, Heymann W, von Lieres E, Schlegel F, Westerberg K, Lenhoff AM. Robust mechanistic modeling of protein ion-exchange chromatography. Journal of Chromatography. A. 1660: 462669. PMID 34800897 DOI: 10.1016/j.chroma.2021.462669  0.371
2021 Greene DG, Modla S, Sandler SI, Wagner NJ, Lenhoff AM. Nanocrystalline protein domains via salting-out. Acta Crystallographica. Section F, Structural Biology Communications. 77: 412-419. PMID 34726180 DOI: 10.1107/S2053230X21009961  0.302
2020 Khanal O, Kumar V, Lenhoff AM. Displacement to separate host cell proteins and aggregates in cation-exchange chromatography of monoclonal antibodies. Biotechnology and Bioengineering. PMID 32910459 DOI: 10.1002/Bit.27559  0.399
2020 Roush D, Asthagiri D, Babi DK, Benner S, Bilodeau C, Carta G, Ernst P, Fedesco M, Fitzgibbon S, Flamm M, Griesbach J, Grosskopf T, Hansen EB, Hahn T, Hunt S, ... ... Lenhoff A, et al. Toward in silico CMC: An industrial collaborative approach to model-based process development. Biotechnology and Bioengineering. PMID 32725887 DOI: 10.1002/Bit.27520  0.612
2020 Kumar V, Lenhoff AM. Mechanistic Modeling of Preparative Column Chromatography for Biotherapeutics. Annual Review of Chemical and Biomolecular Engineering. 11: 235-255. PMID 32513085 DOI: 10.1146/Annurev-Chembioeng-102419-125430  0.31
2020 Khanal O, Kumar V, Schlegel F, Lenhoff AM. Estimating and leveraging protein diffusion on ion-exchange resin surfaces. Proceedings of the National Academy of Sciences of the United States of America. PMID 32179691 DOI: 10.1073/Pnas.1921499117  0.461
2019 Khanal O, Xu X, Singh N, Traylor SJ, Huang C, Ghose S, Li ZJ, Lenhoff AM. DNA RETENTION ON DEPTH FILTERS. Journal of Membrane Science. 570: 464-471. PMID 31223185 DOI: 10.1016/J.Memsci.2018.10.058  0.77
2018 Khanal O, Kumar V, Westerberg K, Schlegel F, Lenhoff AM. Multi-column displacement chromatography for separation of charge variants of monoclonal antibodies. Journal of Chromatography. A. PMID 30573313 DOI: 10.1016/J.Chroma.2018.11.074  0.327
2018 Koshari SHS, Nayak PK, Burra S, Zarraga IE, Rajagopal K, Liu Y, Wagner NJ, Lenhoff AM. In situ characterization of the microstructural evolution of biopharmaceutical solid-state formulations with implications for protein stability. Molecular Pharmaceutics. PMID 30484319 DOI: 10.1021/Acs.Molpharmaceut.8B00935  0.355
2018 Greene DG, Traylor SJ, Guo J, Choe LH, Modla S, Xu X, Singh N, Lock LL, Ghose S, Li ZJ, Lee KH, Wagner NJ, Lenhoff AM. Mechanisms of precipitate formation during the purification of an Fc-fusion protein. Biotechnology and Bioengineering. PMID 29896879 DOI: 10.1002/Bit.26746  0.81
2018 Khanal O, Singh N, Traylor SJ, Xu X, Ghose S, Li ZJ, Lenhoff AM. Contributions of Depth Filter Components to Protein Adsorption in Protein Bioprocessing. Biotechnology and Bioengineering. PMID 29663326 DOI: 10.1002/Bit.26707  0.799
2018 Khanal O, Singh N, Traylor SJ, Xu X, Ghose S, Li ZJ, Lenhoff AM. Contributions of Depth Filter Components to Protein Adsorption in Protein Bioprocessing. Biotechnology and Bioengineering. PMID 29644625 DOI: 10.1002/bit.26607  0.8
2018 Valente KN, Levy NE, Lee KH, Lenhoff AM. Applications of proteomic methods for CHO host cell protein characterization in biopharmaceutical manufacturing. Current Opinion in Biotechnology. 53: 144-150. PMID 29414072 DOI: 10.1016/J.Copbio.2018.01.004  0.713
2017 Koshari SHS, Wagner NJ, Lenhoff AM. Effects of Resin Architecture and Protein Size on Nanoscale Protein Distribution in Ion-Exchange Media. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29286243 DOI: 10.1021/Acs.Langmuir.7B03289  0.478
2017 Liu T, Angelo JM, Lin DQ, Lenhoff AM, Yao SJ. Characterization of dextran-grafted hydrophobic charge-induction resins: Structural properties, protein adsorption and transport. Journal of Chromatography. A. PMID 28855091 DOI: 10.1016/J.Chroma.2017.07.090  0.433
2017 Bhambure R, Angelo JM, Gillespie CM, Phillips M, Graalfs H, Lenhoff AM. Ionic strength-dependent changes in tentacular ion exchangers with variable ligand density. II. Functional properties. Journal of Chromatography. A. PMID 28554867 DOI: 10.1016/j.chroma.2017.05.021  0.707
2017 Koshari SH, Ross JL, Nayak PK, Zarraga IE, Rajagopal K, Wagner NJ, Lenhoff AM. Characterization of Protein-Excipient Microheterogeneity in Biopharmaceutical Solid-State Formulations by Confocal Fluorescence Microscopy. Molecular Pharmaceutics. PMID 28094996 DOI: 10.1021/Acs.Molpharmaceut.6B00940  0.391
2016 Halvorson J, Lenhoff AM, Dittmann M, Stoll DR. Implications of turbulent flow in connecting capillaries used in high performance liquid chromatography. Journal of Chromatography. A. PMID 28073451 DOI: 10.1016/J.Chroma.2016.12.084  0.33
2016 Chiu J, Valente KN, Levy NE, Min L, Lenhoff AM, Lee KH. Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations. Biotechnology and Bioengineering. PMID 27943242 DOI: 10.1002/Bit.26237  0.701
2016 Bhambure R, Gillespie CM, Phillips M, Graalfs H, Lenhoff AM. Ionic strength-dependent changes in tentacular ion exchangers with variable ligand density. I. Structural properties. Journal of Chromatography. A. PMID 27544749 DOI: 10.1016/J.Chroma.2016.08.010  0.692
2016 Angelo JM, Lenhoff AM. Determinants of protein elution rates from preparative ion-exchange adsorbents. Journal of Chromatography. A. 1440: 94-104. PMID 26948763 DOI: 10.1016/J.Chroma.2016.02.048  0.492
2016 Angelo JM, Cvetkovic A, Gantier R, Lenhoff AM. Characterization of cross-linked cellulosic ion-exchange adsorbents: 2. Protein sorption and transport. Journal of Chromatography. A. 1438: 100-12. PMID 26905881 DOI: 10.1016/J.Chroma.2016.02.019  0.511
2016 Greene DG, Ferraro DV, Lenhoff AM, Wagner NJ. A critical examination of the decoupling approximation for small-angle scattering from hard ellipsoids of revolution Journal of Applied Crystallography. 49: 1734-1739. DOI: 10.1107/S1600576716012929  0.31
2016 Lenhoff AM. Ion-exchange chromatography of proteins: the inside story Materials Today: Proceedings. 3: 3559-3567. DOI: 10.1016/J.Matpr.2016.10.038  0.462
2015 Levy NE, Valente KN, Lee KH, Lenhoff AM. Host cell protein impurities in chromatographic polishing steps for monoclonal antibody purification. Biotechnology and Bioengineering. PMID 26550778 DOI: 10.1002/Bit.25882  0.709
2015 Greene DG, Modla S, Wagner NJ, Sandler SI, Lenhoff AM. Local Crystalline Structure in an Amorphous Protein Dense Phase. Biophysical Journal. 109: 1716-1723. PMID 26488663 DOI: 10.1016/J.Bpj.2015.08.023  0.355
2015 Koshari SH, Wagner NJ, Lenhoff AM. Characterization of lysozyme adsorption in cellulosic chromatographic materials using small-angle neutron scattering. Journal of Chromatography. A. 1399: 45-52. PMID 25964231 DOI: 10.1016/j.chroma.2015.04.042  0.351
2015 Gu F, Chodavarapu K, McCreary D, Plitt TA, Tamoria E, Ni M, Burnham JJ, Peters M, Lenhoff AM. Silica-based strong anion exchange media for protein purification. Journal of Chromatography. A. 1376: 53-63. PMID 25537176 DOI: 10.1016/J.Chroma.2014.11.082  0.425
2015 Valente KN, Lenhoff AM, Lee KH. Expression of difficult-to-remove host cell protein impurities during extended Chinese hamster ovary cell culture and their impact on continuous bioprocessing. Biotechnology and Bioengineering. 112: 1232-42. PMID 25502542 DOI: 10.1002/Bit.25515  0.344
2015 Lewus RA, Levy NE, Lenhoff AM, Sandler SI. A comparative study of monoclonal antibodies. 1. Phase behavior and protein-protein interactions. Biotechnology Progress. 31: 268-76. PMID 25378269 DOI: 10.1002/Btpr.2011  0.726
2015 Samadzoda A, Vaish A, Robinson AS, Lenhoff A. Mechanisms of Membrane Protein Crystallization Biophysical Journal. 108: 247a. DOI: 10.1016/J.Bpj.2014.11.1369  0.375
2014 Quang LJ, Sandler SI, Lenhoff AM. Anisotropic Contributions to Protein-Protein Interactions. Journal of Chemical Theory and Computation. 10: 835-45. PMID 26580057 DOI: 10.1021/Ct4006695  0.416
2014 Gillespie CM, Asthagiri D, Lenhoff AM. Polymorphic Protein Crystal Growth: Influence of Hydration and Ions in Glucose Isomerase. Crystal Growth & Design. 14: 46-57. PMID 24955067 DOI: 10.1021/Cg401063B  0.698
2014 Traylor SJ, Bowes BD, Ammirati AP, Timmick SM, Lenhoff AM. Fluorescence recovery after photobleaching investigation of protein transport and exchange in chromatographic media. Journal of Chromatography. A. 1340: 33-49. PMID 24685162 DOI: 10.1016/J.Chroma.2014.02.072  0.816
2014 Levy NE, Valente KN, Choe LH, Lee KH, Lenhoff AM. Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing. Biotechnology and Bioengineering. 111: 904-12. PMID 24254318 DOI: 10.1002/Bit.25158  0.713
2014 Valente KN, Schaefer AK, Kempton HR, Lenhoff AM, Lee KH. Recovery of Chinese hamster ovary host cell proteins for proteomic analysis. Biotechnology Journal. 9: 87-99. PMID 24039059 DOI: 10.1002/Biot.201300190  0.387
2013 Angelo JM, Cvetkovic A, Gantier R, Lenhoff AM. Characterization of cross-linked cellulosic ion-exchange adsorbents: 1. Structural properties. Journal of Chromatography. A. 1319: 46-56. PMID 24188996 DOI: 10.1016/J.Chroma.2013.10.003  0.383
2013 Johnson HR, Lenhoff AM. Characterization and suitability of therapeutic antibody dense phases for subcutaneous delivery. Molecular Pharmaceutics. 10: 3582-91. PMID 24011376 DOI: 10.1021/Mp400006G  0.355
2013 Samadzoda A, Lenhoff A, Robinson A. Characterizing Interactions between Surfactants and Membrane Proteins with Special Emphasis on Crystallization Biophysical Journal. 104: 218a. DOI: 10.1016/J.Bpj.2012.11.1233  0.364
2012 Valente KN, Choe LH, Lenhoff AM, Lee KH. Optimization of protein sample preparation for two-dimensional electrophoresis. Electrophoresis. 33: 1947-57. PMID 22806459 DOI: 10.1002/Elps.201100659  0.396
2012 Koku H, Maier RS, Schure MR, Lenhoff AM. Modeling of dispersion in a polymeric chromatographic monolith. Journal of Chromatography. A. 1237: 55-63. PMID 22465685 DOI: 10.1016/J.Chroma.2012.03.005  0.762
2012 Bowes BD, Traylor SJ, Timmick SM, Czymmek KJ, Lenhoff AM. Insights into protein sorption and desorption on dextran-modified ion-exchange media Chemical Engineering and Technology. 35: 91-101. DOI: 10.1002/Ceat.201100304  0.81
2011 Bowes BD, Lenhoff AM. Protein adsorption and transport in dextran-modified ion-exchange media. III. Effects of resin charge density and dextran content on adsorption and intraparticle uptake. Journal of Chromatography. A. 1218: 7180-8. PMID 21890143 DOI: 10.1016/J.Chroma.2011.08.039  0.813
2011 Lenhoff AM. Protein adsorption and transport in polymer-functionalized ion-exchangers. Journal of Chromatography. A. 1218: 8748-59. PMID 21752388 DOI: 10.1016/J.Chroma.2011.06.061  0.468
2011 Bowes BD, Lenhoff AM. Protein adsorption and transport in dextran-modified ion-exchange media. II. Intraparticle uptake and column breakthrough. Journal of Chromatography. A. 1218: 4698-708. PMID 21683363 DOI: 10.1016/J.Chroma.2011.05.054  0.827
2011 Koku H, Maier RS, Czymmek KJ, Schure MR, Lenhoff AM. Modeling of flow in a polymeric chromatographic monolith. Journal of Chromatography. A. 1218: 3466-75. PMID 21529814 DOI: 10.1016/J.Chroma.2011.03.064  0.739
2011 Maurer RW, Sandler SI, Lenhoff AM. Salting-in characteristics of globular proteins Biophysical Chemistry. 156: 72-78. PMID 21420225 DOI: 10.1016/J.Bpc.2011.02.002  0.409
2011 Traylor SJ, Xu X, Lenhoff AM. Shrinking-core modeling of binary chromatographic breakthrough. Journal of Chromatography. A. 1218: 2222-31. PMID 21411102 DOI: 10.1016/J.Chroma.2011.02.020  0.799
2011 Lewus RA, Darcy PA, Lenhoff AM, Sandler SI. Interactions and phase behavior of a monoclonal antibody Biotechnology Progress. 27: 280-289. PMID 21312375 DOI: 10.1002/Btpr.536  0.383
2011 Martin C, Lenhoff AM. Self-interaction chromatography of proteins on a microfluidic monolith. Biochemical Engineering Journal. 53: 216-22. PMID 21258647 DOI: 10.1016/J.Bej.2010.10.016  0.436
2011 To BC, Lenhoff AM. Hydrophobic interaction chromatography of proteins. IV. Protein adsorption capacity and transport in preparative mode. Journal of Chromatography. A. 1218: 427-40. PMID 21176838 DOI: 10.1016/J.Chroma.2010.11.051  0.52
2010 Bianco CL, Schneider CS, Santonicola M, Lenhoff AM, Kaler EW. Effects of urea on the microstructure and phase behavior of aqueous solutions of polyoxyethylene surfactants. Industrial & Engineering Chemistry Research. 50: 85-96. PMID 21359094 DOI: 10.1021/Ie101011V  0.343
2010 Trilisky EI, Lenhoff AM. Effect of bioparticle size on dispersion and retention in monolithic and perfusive beds. Journal of Chromatography. A. 1217: 7372-84. PMID 20951383 DOI: 10.1016/J.Chroma.2010.09.040  0.812
2010 Roth CM, Lenhoff AM. ChemInform Abstract: Quantitative Modeling of Protein Adsorption Cheminform. 30: no-no. DOI: 10.1002/chin.199914339  0.302
2009 Bowes BD, Koku H, Czymmek KJ, Lenhoff AM. Protein adsorption and transport in dextran-modified ion-exchange media. I: adsorption. Journal of Chromatography. A. 1216: 7774-84. PMID 19801150 DOI: 10.1016/J.Chroma.2009.09.014  0.819
2009 Trilisky EI, Koku H, Czymmek KJ, Lenhoff AM. Relation of structure to performance characteristics of monolithic and perfusive stationary phases. Journal of Chromatography. A. 1216: 6365-76. PMID 19646709 DOI: 10.1016/J.Chroma.2009.07.005  0.775
2009 Xu X, Lenhoff AM. Binary adsorption of globular proteins on ion-exchange media. Journal of Chromatography. A. 1216: 6177-95. PMID 19631326 DOI: 10.1016/J.Chroma.2009.06.082  0.612
2009 Trilisky EI, Lenhoff AM. Flow-dependent entrapment of large bioparticles in porous process media. Biotechnology and Bioengineering. 104: 127-33. PMID 19459138 DOI: 10.1002/Bit.22370  0.787
2009 Dumetz AC, Chockla AM, Kaler EW, Lenhoff AM. Comparative effects of salt, organic, and polymer precipitants on protein phase behavior and implications for vapor diffusion Crystal Growth and Design. 9: 682-691. DOI: 10.1021/Cg700956B  0.389
2008 To BC, Lenhoff AM. Hydrophobic interaction chromatography of proteins III. Transport and kinetic parameters in isocratic elution. Journal of Chromatography. A. 1205: 46-59. PMID 18718599 DOI: 10.1016/J.Chroma.2008.07.079  0.482
2008 Dumetz AC, Lewus RA, Lenhoff AM, Kaler EW. Effects of ammonium sulfate and sodium chloride concentration on PEG/protein liquid-liquid phase separation. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 10345-51. PMID 18702478 DOI: 10.1021/La801180N  0.382
2008 Lenhoff AM. Multiscale modeling of protein uptake patterns in chromatographic particles Langmuir. 24: 5991-5995. PMID 18481880 DOI: 10.1021/La8004163  0.471
2008 Tessier PM, Jinkoji J, Cheng YC, Prentice JL, Lenhoff AM. Self-interaction nanoparticle spectroscopy: a nanoparticle-based protein interaction assay. Journal of the American Chemical Society. 130: 3106-12. PMID 18271584 DOI: 10.1021/Ja077624Q  0.391
2008 Dumetz AC, Chockla AM, Kaler EW, Lenhoff AM. Effects of pH on protein-protein interactions and implications for protein phase behavior. Biochimica Et Biophysica Acta. 1784: 600-10. PMID 18258214 DOI: 10.1016/J.Bbapap.2007.12.016  0.424
2008 Santonicola MG, Lenhoff AM, Kaler EW. Binding of alkyl polyglucoside surfactants to bacteriorhodopsin and its relation to protein stability. Biophysical Journal. 94: 3647-58. PMID 18234822 DOI: 10.1529/Biophysj.107.113258  0.403
2008 Xu X, Lenhoff AM. A predictive approach to correlating protein adsorption isotherms on ion-exchange media. The Journal of Physical Chemistry. B. 112: 1028-40. PMID 18171041 DOI: 10.1021/Jp0754233  0.661
2008 Dumetz AC, Chockla AM, Kaler EW, Lenhoff AM. Protein phase behavior in aqueous solutions: crystallization, liquid-liquid phase separation, gels, and aggregates. Biophysical Journal. 94: 570-83. PMID 18160663 DOI: 10.1529/Biophysj.107.116152  0.379
2008 Cheng YC, Bianco CL, Sandler SI, Lenhoff AM. Salting-out of lysozyme and ovalbumin from mixtures: Predicting precipitation performance from protein-protein interactions Industrial and Engineering Chemistry Research. 47: 5203-5213. DOI: 10.1021/Ie071462P  0.451
2008 Bowes BD, Koku H, Lenhoff AM. Examining the effect of protein size on transport and adsorption in polymer-modified ion-exchange Media Aiche Annual Meeting, Conference Proceedings 0.794
2007 Dumetz AC, Snellinger-O'brien AM, Kaler EW, Lenhoff AM. Patterns of protein protein interactions in salt solutions and implications for protein crystallization. Protein Science : a Publication of the Protein Society. 16: 1867-77. PMID 17766383 DOI: 10.1110/Ps.072957907  0.448
2007 Langford JF, Xu X, Yao Y, Maloney SF, Lenhoff AM. Chromatography of proteins on charge-variant ion exchangers and implications for optimizing protein uptake rates. Journal of Chromatography. A. 1163: 190-202. PMID 17640661 DOI: 10.1016/J.Chroma.2007.06.028  0.83
2007 Trilisky EI, Lenhoff AM. Sorption processes in ion-exchange chromatography of viruses. Journal of Chromatography. A. 1142: 2-12. PMID 17240385 DOI: 10.1016/J.Chroma.2006.12.094  0.802
2007 To BC, Lenhoff AM. Hydrophobic interaction chromatography of proteins. I. The effects of protein and adsorbent properties on retention and recovery. Journal of Chromatography. A. 1141: 191-205. PMID 17207806 DOI: 10.1016/J.Chroma.2006.12.020  0.492
2007 To BC, Lenhoff AM. Hydrophobic interaction chromatography of proteins. II. Solution thermodynamic properties as a determinant of retention. Journal of Chromatography. A. 1141: 235-43. PMID 17207494 DOI: 10.1016/J.Chroma.2006.12.022  0.487
2007 Vivares D, Kaler EW, Lenhoff AM. Polyhedral instability of glucose isomerase crystals as revealed by confocal scanning fluorescence microscopy Crystal Growth and Design. 7: 1411-1415. DOI: 10.1021/Cg060787Q  0.325
2006 Yao Y, Czymmek KJ, Pazhianur R, Lenhoff AM. Three-dimensional pore structure of chromatographic adsorbents from electron tomography. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 11148-57. PMID 17154596 DOI: 10.1021/La0613225  0.483
2006 Berger BW, Gendron CM, Lenhoff AM, Kaler EW. Effects of additives on surfactant phase behavior relevant to bacteriorhodopsin crystallization. Protein Science : a Publication of the Protein Society. 15: 2682-96. PMID 17088325 DOI: 10.1110/Ps.062370506  0.647
2006 Langford JF, Schure MR, Yao Y, Maloney SF, Lenhoff AM. Effects of pore structure and molecular size on diffusion in chromatographic adsorbents. Journal of Chromatography. A. 1126: 95-106. PMID 16854421 DOI: 10.1016/J.Chroma.2006.06.060  0.796
2006 Yao Y, Lenhoff AM. Pore size distributions of ion exchangers and relation to protein binding capacity. Journal of Chromatography. A. 1126: 107-19. PMID 16844131 DOI: 10.1016/J.Chroma.2006.06.057  0.558
2006 Cheng YC, Lobo RF, Sandler SI, Lenhoff AM. Kinetics and equilibria of lysozyme precipitation and crystallization in concentrated ammonium sulfate solutions Biotechnology and Bioengineering. 94: 177-188. PMID 16570321 DOI: 10.1002/Bit.20839  0.352
2006 Yao Y, Lenhoff AM. Erratum to “Determination of pore size distributions of porous chromatographic adsorbents by inverse size-exclusion chromatography” [J. Chromatogr. A 1037 (2004) 273–282] Journal of Chromatography A. 1113: 259. DOI: 10.1016/J.Chroma.2006.02.085  0.446
2005 Paliwal A, Asthagiri D, Abras D, Lenhoff AM, Paulaitis ME. Light-scattering studies of protein solutions: Role of hydration in weak protein-protein interactions Biophysical Journal. 89: 1564-1573. PMID 15980182 DOI: 10.1529/Biophysj.105.065284  0.767
2005 Vivarès D, Kaler EW, Lenhoff AM. Quantitative imaging by confocal scanning fluorescence microscopy of protein crystallization via liquid-liquid phase separation. Acta Crystallographica. Section D, Biological Crystallography. 61: 819-25. PMID 15930647 DOI: 10.1107/S090744490402949X  0.344
2005 Berger BW, Gendron CM, Robinson CR, Kaler EW, Lenhoff AM. The role of protein and surfactant interactions in membrane-protein crystallization. Acta Crystallographica. Section D, Biological Crystallography. 61: 724-30. PMID 15930629 DOI: 10.1107/S0907444904029063  0.653
2005 Dziennik SR, Belcher EB, Barker GA, Lenhoff AM. Effects of ionic strength on lysozyme uptake rates in cation exchangers. I: Uptake in SP Sepharose FF. Biotechnology and Bioengineering. 91: 139-53. PMID 15889407 DOI: 10.1002/Bit.20503  0.798
2005 Berger BW, García RY, Lenhoff AM, Kaler EW, Robinson CR. Relating surfactant properties to activity and solubilization of the human adenosine a3 receptor. Biophysical Journal. 89: 452-64. PMID 15849244 DOI: 10.1529/Biophysj.104.051417  0.601
2005 Yao Y, Lenhoff AM. Electrostatic contributions to protein retention in ion-exchange chromatography. 2. Proteins with various degrees of structural differences. Analytical Chemistry. 77: 2157-65. PMID 15801750 DOI: 10.1021/Ac048733F  0.611
2005 Asthagiri D, Paliwal A, Abras D, Lenhoff AM, Paulaitis ME. A consistent experimental and modeling approach to light-scattering studies of protein-protein interactions in solution Biophysical Journal. 88: 3300-3309. PMID 15792969 DOI: 10.1529/Biophysj.104.058859  0.771
2005 Berger BW, Blamey CJ, Naik UP, Bahnson BJ, Lenhoff AM. Roles of additives and precipitants in crystallization of calcium- and integrin-binding protein Crystal Growth and Design. 5: 1499-1507. DOI: 10.1021/Cg050013U  0.656
2004 Yao Y, Lenhoff AM. Electrostatic contributions to protein retention in ion-exchange chromatography. 1. Cytochrome C variants. Analytical Chemistry. 76: 6743-52. PMID 15538799 DOI: 10.1021/Ac049327Z  0.592
2004 DePhillips P, Lagerlund I, Färenmark J, Lenhoff AM. Effect of spacer arm length on protein retention on a strong cation exchange adsorbent. Analytical Chemistry. 76: 5816-22. PMID 15456302 DOI: 10.1021/Ac049462B  0.454
2004 Tessier PM, Verruto VJ, Sandler SI, Lenhoff AM. Correlation of diafiltration sieving behavior of lysozyme-BSA mixtures with osmotic second virial cross-coefficients. Biotechnology and Bioengineering. 87: 303-10. PMID 15281105 DOI: 10.1002/Bit.20115  0.441
2004 Chang J, Lenhoff AM, Sandler SI. Determination of fluid--solid transitions in model protein solutions using the histogram reweighting method and expanded ensemble simulations. The Journal of Chemical Physics. 120: 3003-14. PMID 15268448 DOI: 10.1063/1.1638377  0.377
2004 Yao Y, Lenhoff AM. Determination of pore size distributions of porous chromatographic adsorbents by inverse size-exclusion chromatography. Journal of Chromatography. A. 1037: 273-82. PMID 15214670 DOI: 10.1016/J.Chroma.2004.02.054  0.518
2004 DePhillips P, Lenhoff AM. Relative retention of the fibroblast growth factors FGF-1 and FGF-2 on strong cation-exchange sorbents. Journal of Chromatography. A. 1036: 51-60. PMID 15139413 DOI: 10.1016/J.Chroma.2004.01.012  0.382
2004 Tessier PM, Sandler SI, Lenhoff AM. Direct measurement of protein osmotic second virial cross coefficients by cross-interaction chromatography. Protein Science : a Publication of the Protein Society. 13: 1379-90. PMID 15075404 DOI: 10.1110/Ps.03419204  0.388
2003 Yuan Y, Lenhoff AM. Measurement of mobility of adsorbed colloids by lateral force microscopy. Journal of Colloid and Interface Science. 267: 352-9. PMID 14583212 DOI: 10.1016/S0021-9797(03)00577-0  0.54
2003 Tessier PM, Lenhoff AM. Measurements of protein self-association as a guide to crystallization. Current Opinion in Biotechnology. 14: 512-6. PMID 14580581 DOI: 10.1016/S0958-1669(03)00114-9  0.422
2003 Dziennik SR, Belcher EB, Barker GA, DeBergalis MJ, Fernandez SE, Lenhoff AM. Nondiffusive mechanisms enhance protein uptake rates in ion exchange particles. Proceedings of the National Academy of Sciences of the United States of America. 100: 420-5. PMID 12522150 DOI: 10.1073/Pnas.0237084100  0.806
2003 Tessier PM, Johnson HR, Pazhianur R, Berger BW, Prentice JL, Bahnson BJ, Sandler SI, Lenhoff AM. Predictive crystallization of ribonuclease A via rapid screening of osmotic second virial coefficients. Proteins. 50: 303-11. PMID 12486724 DOI: 10.1002/Prot.10249  0.63
2003 Yuan Y, Velev OD, Lenhoff AM. Mobility of adsorbed proteins studied by fluorescence recovery after photobleaching Langmuir. 19: 3705-3711. DOI: 10.1021/La026368M  0.631
2002 Tessier PM, Vandrey SD, Berger BW, Pazhianur R, Sandler SI, Lenhoff AM. Self-interaction chromatography: a novel screening method for rational protein crystallization. Acta Crystallographica. Section D, Biological Crystallography. 58: 1531-5. PMID 12351855 DOI: 10.1107/S0907444902012775  0.627
2002 Yuan YJ, Velev OD, Chen K, Campbell BE, Kaler EW, Lenhoff AM. Effect of pH and Ca2+-induced associations of soybean proteins. Journal of Agricultural and Food Chemistry. 50: 4953-8. PMID 12166988 DOI: 10.1021/Jf025582D  0.624
2002 Tessier PM, Lenhoff AM, Sandler SI. Rapid measurement of protein osmotic second virial coefficients by self-interaction chromatography. Biophysical Journal. 82: 1620-31. PMID 11867474 DOI: 10.1016/S0006-3495(02)75513-6  0.447
2001 DePhillips P, Lenhoff AM. Determinants of protein retention characteristics on cation-exchange adsorbents Journal of Chromatography A. 933: 57-72. PMID 11758747 DOI: 10.1016/S0021-9673(01)01275-4  0.488
2001 Ruppert S, Sandler SI, Lenhoff AM. Correlation between the osmotic second virial coefficient and the solubility of proteins. Biotechnology Progress. 17: 182-7. PMID 11170497 DOI: 10.1021/Bp0001314  0.425
2001 Hloucha M, Lodge JFM, Lenhoff AM, Sandler SI. A patch-antipatch representation of specific protein interactions Journal of Crystal Growth. 232: 195-203. DOI: 10.1016/S0022-0248(01)01151-4  0.406
2000 Moretti JJ, Sandler SI, Lenhoff AM. Phase equilibria in the lysozyme-ammonium sulfate-water system. Biotechnology and Bioengineering. 70: 498-506. PMID 11042546 DOI: 10.1002/1097-0290(20001205)70:5<498::Aid-Bit4>3.0.Co;2-6  0.35
2000 Chang RC, Asthagiri D, Lenhoff AM. Measured and calculated effects of mutations in bacteriophage T4 lysozyme on interactions solution Proteins: Structure, Function and Genetics. 41: 123-132. PMID 10944399 DOI: 10.1002/1097-0134(20001001)41:1<123::Aid-Prot140>3.0.Co;2-Q  0.425
2000 DePhillips P, Lenhoff AM. Pore size distributions of cation-exchange adsorbents determined by inverse size-exclusion chromatography Journal of Chromatography A. 883: 39-54. PMID 10910199 DOI: 10.1016/S0021-9673(00)00420-9  0.391
2000 Johnson CA, Yuan Y, Lenhoff AM. Adsorbed Layers of Ferritin at Solid and Fluid Interfaces Studied by Atomic Force Microscopy. Journal of Colloid and Interface Science. 223: 261-272. PMID 10700411 DOI: 10.1006/Jcis.1999.6680  0.617
2000 Yuan Y, Oberholzer MR, Lenhoff AM. Size does matter: Electrostatically determined surface coverage trends in protein and colloid adsorption Colloids and Surfaces a: Physicochemical and Engineering Aspects. 165: 125-141. DOI: 10.1016/S0927-7757(99)00418-5  0.586
2000 Asthagiri D, Lenhoff AM, Gallagher DT. Role of competitive interactions in growth rate trends of subtilisin s88 crystals Journal of Crystal Growth. 212: 543-554. DOI: 10.1016/S0022-0248(00)00200-1  0.662
1999 Asthagiri D, Neal BL, Lenhoff AM. Calculation of short-range interactions between proteins. Biophysical Chemistry. 78: 219-31. PMID 17030310 DOI: 10.1016/S0301-4622(99)00028-9  0.659
1999 Oberholzer MR, Lenhoff AM. Protein adsorption isotherms through colloidal energetics Langmuir. 15: 3905-3914. DOI: 10.1021/La981199K  0.472
1999 Yuan Y, Lenhoff AM. Characterization of Phase Separation in Mixed Surfactant Films by Liquid Tapping Mode Atomic Force Microscopy Langmuir. 15: 3021-3025. DOI: 10.1021/La980879K  0.559
1999 Neal BL, Asthagiri D, Velev OD, Lenhoff AM, Kaler EW. Why is the osmotic second virial coefficient related to protein crystallization? Journal of Crystal Growth. 196: 377-387. DOI: 10.1016/S0022-0248(98)00855-0  0.707
1998 Chang C, Lenhoff AM. Comparison of protein adsorption isotherms and uptake rates in preparative cation-exchange materials Journal of Chromatography A. 827: 281-293. PMID 9914656 DOI: 10.1016/S0021-9673(98)00796-1  0.412
1998 Velev OD, Kaler EW, Lenhoff AM. Protein interactions in solution characterized by light and neutron scattering: comparison of lysozyme and chymotrypsinogen. Biophysical Journal. 75: 2682-97. PMID 9826592 DOI: 10.1016/S0006-3495(98)77713-6  0.407
1998 Neal BL, Asthagiri D, Lenhoff AM. Molecular origins of osmotic second virial coefficients of proteins Biophysical Journal. 75: 2469-2477. PMID 9788942 DOI: 10.1016/S0006-3495(98)77691-X  0.709
1998 Velev OD, Jede TA, Lobo RF, Lenhoff AM. Microstructured Porous Silica Obtained via Colloidal Crystal Templates Chemistry of Materials. 10: 3597-3602. DOI: 10.1021/Cm980444I  0.344
1998 Roth CM, Sader JE, Lenhoff AM. Electrostatic contribution to the energy and entropy of protein adsorption Journal of Colloid and Interface Science. 203: 218-221. DOI: 10.1006/jcis.1998.5479  0.344
1997 Oberholzer MR, Wagner NJ, Lenhoff AM. Grand canonical Brownian dynamics simulation of colloidal adsorption Journal of Chemical Physics. 107: 9157-9167. DOI: 10.1063/1.475207  0.399
1997 Asthagiri D, Lenhoff AM. Influence of structural details in modeling electrostatically driven protein adsorption Langmuir. 13: 6761-6768. DOI: 10.1021/La970608U  0.438
1997 Lenhoff AM, Pjura PE, Dilmore JG, Godlewski TS. Ultracentrifugal crystallization of proteins: Transport-kinetic modelling, and experimental behavior of catalase Journal of Crystal Growth. 180: 113-126. DOI: 10.1016/S0022-0248(97)00207-8  0.418
1997 Oberholzer MR, Stankovich JM, Carnie SL, Chan DYC, Lenhoff AM. 2-D and 3-D interactions in random sequential adsorption of charged particles Journal of Colloid and Interface Science. 194: 138-153. DOI: 10.1006/Jcis.1997.5095  0.346
1996 Roth CM, Neal BL, Lenhoff AM. Van der Waals interactions involving proteins Biophysical Journal. 70: 977-987. PMID 8789115 DOI: 10.1016/S0006-3495(96)79641-8  0.432
1996 Palkar SA, Lenhoff AM. Diffusion and adsorption of proteins in a model pore in the surface forces apparatus Colloids and Surfaces a: Physicochemical and Engineering Aspects. 110: 119-127. DOI: 10.1016/0927-7757(95)03435-8  0.321
1996 Roth CM, Unger KK, Lenhoff AM. Mechanistic model of retention in protein ion-exchange chromatography Journal of Chromatography A. 726: 45-56. DOI: 10.1016/0021-9673(95)01043-2  0.433
1995 Kyung Sun Chae, Lenhoff AM. Computation of the electrophoretic mobility of proteins Biophysical Journal. 68: 1120-1127. PMID 7756531 DOI: 10.1016/S0006-3495(95)80286-9  0.385
1995 Roth CM, Lenhoff AM. Electrostatic and Van Der Waals contributions to protein adsorption: Comparison of theory and experiment Langmuir. 11: 3500-3509. DOI: 10.1021/La00009A036  0.48
1995 Palkar SA, Lenhoff AM. Effect of taper on diffusion and adsorption in a cylindrical pore Industrial &Amp; Engineering Chemistry Research. 34: 3551-3555. DOI: 10.1021/Ie00037A044  0.41
1995 Neal BL, Lenhoff AM. Excluded volume contribution to the osmotic second virial coefficient for proteins Aiche Journal. 41: 1010-1014. DOI: 10.1002/Aic.690410432  0.404
1995 Pjura PE, Paulaitis ME, Lenhoff AM. Molecular thermodynamic properties of protein solutions from partial specific volumes Aiche Journal. 41: 1005-1009. DOI: 10.1002/Aic.690410431  0.652
1994 Palkar SA, Lenhoff AM. Energetic and Entropic Contributions to the Interaction of Unequal Spherical Double Layers Journal of Colloid and Interface Science. 165: 177-194. DOI: 10.1006/Jcis.1994.1219  0.303
1994 Johnson CA, Wu P, Lenhoff AM. Electrostatic and van der waals contributions to protein adsorption. 2. modeling of ordered arrays Langmuir. 10: 3705-3713.  0.365
1993 Haggerty L, Lenhoff AM. Analysis of ordered arrays of adsorbed lysozyme by scanning tunneling microscopy Biophysical Journal. 64: 886-895. PMID 8471732 DOI: 10.1016/S0006-3495(93)81448-6  0.459
1993 Roth CM, Lenhoff AM. Electrostatic and van der Wals contributions to protein adsorption: Computation of equilibrium constants Langmuir. 9: 962-972. DOI: 10.1021/La00028A015  0.481
1993 Schure MR, Lenhoff AM. Consequences of wall adsorption in capillary electrophoresis: Theory and simulation Analytical Chemistry. 65: 3024-3037. DOI: 10.1021/Ac00069A015  0.373
1992 Yoon BJ, Lenhoff AM. Computation of the electrostatic interaction energy between a protein and a charged surface Journal of Physical Chemistry. 96: 3130-3134. DOI: 10.1021/J100186A064  0.371
1992 Shibata CT, Lenhoff AM. TIRF of salt and surface effects on protein adsorption. II. Kinetics Journal of Colloid and Interface Science. 148: 485-507. DOI: 10.1016/0021-9797(92)90185-O  0.436
1992 Shibata CT, Lenhoff AM. TIRF of salt and surface effects on protein adsorption. I. Equilibrium Journal of Colloid and Interface Science. 148: 469-484. DOI: 10.1016/0021-9797(92)90184-N  0.432
1991 Shankar A, Lenhoff AM. Dispersion and partitioning in short coated tubes Industrial and Engineering Chemistry Research. 30: 828-835. DOI: 10.1021/Ie00053A004  0.321
1991 Shankar A, Lenhoff AM. Dispersion in round tubes and its implications for extracolumn dispersion Journal of Chromatography A. 556: 235-248. DOI: 10.1016/S0021-9673(01)96224-7  0.322
1991 Haggerty L, Lenhoff AM. Relation of protein electrostatics computations to ion-exchange and electrophoretic behavior Journal of Physical Chemistry. 95: 1472-1477.  0.343
1987 Lenhoff AM. Significance and estimation of chromatographic parameters Journal of Chromatography A. 384: 285-299. DOI: 10.1016/S0021-9673(01)94678-3  0.355
1986 Lightfoot EN, Rudolph RF, Lenhoff AM, Lanphier EH, Lehner CE, Whiteside LA. Hydrogen washout in bone cortex and periosteum. Undersea Biomedical Research. 13: 425-41. PMID 3810984  0.489
1986 Lenhoff AM, Lightfoot EN. Convective dispersion and interphase mass transfer Chemical Engineering Science. 41: 2795-2810. DOI: 10.1016/0009-2509(86)80011-2  0.553
1984 Lightfoot EN, Lenhoff AM. Microcirculatory mass transfer. Advances in Experimental Medicine and Biology. 180: 13-33. PMID 6534092 DOI: 10.1007/978-1-4684-4895-5_2  0.576
1984 Lenhoff AM, Lightfoot EN. The effects of axial diffusion and permeability barriers on the transient response of tissue cylinders. II. Solution in time domain. Journal of Theoretical Biology. 106: 207-38. PMID 6369004 DOI: 10.1016/0022-5193(84)90020-1  0.516
1983 Lenhoff AM, Lightfoot EN. USE OF NON-SELF-ADJOINT OPERATORS FOR DESCRIBING CONVECTIVE MASS TRANSFER. Annual Meeting - American Institute of Chemical Engineers 0.457
1982 Lenhoff AM, Lightfoot EN. The effects of axial diffusion and permeability barriers on the transient response of tissue cylinders. I. Solution in transform space. Journal of Theoretical Biology. 97: 663-77. PMID 7154686 DOI: 10.1016/0022-5193(82)90365-4  0.516
1982 Lightfoot EN, Lenhoff AM, Rodriguez RL. Use of moments to characterize mass transport in steady flows of arbitrary complexity Chemical Engineering Science. 37: 954-956. DOI: 10.1016/0009-2509(82)80187-5  0.541
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