Laimonis Laimins - Publications

Affiliations: 
Northwestern University, Evanston, IL 
Area:
Microbiology Biology

161 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Templeton CW, Laimins LA. p53-dependent R-loop formation and HPV pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305907120. PMID 37611058 DOI: 10.1073/pnas.2305907120  0.497
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Laimins L, et al. Virology under the Microscope-a Call for Rational Discourse. Msphere. e0003423. PMID 36700653 DOI: 10.1128/msphere.00034-23  0.538
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Laimins L, et al. Virology under the Microscope-a Call for Rational Discourse. Mbio. e0018823. PMID 36700642 DOI: 10.1128/mbio.00188-23  0.538
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Laimins L, et al. Virology under the Microscope-a Call for Rational Discourse. Journal of Virology. e0008923. PMID 36700640 DOI: 10.1128/jvi.00089-23  0.538
2022 Gusho E, Laimins LA. Human papillomaviruses sensitize cells to DNA damage induced apoptosis by targeting the innate immune sensor cGAS. Plos Pathogens. 18: e1010725. PMID 35877778 DOI: 10.1371/journal.ppat.1010725  0.477
2021 Kono T, Laimins L. Genomic Instability and DNA Damage Repair Pathways Induced by Human Papillomaviruses. Viruses. 13. PMID 34578402 DOI: 10.3390/v13091821  0.48
2021 Gusho E, Laimins L. Human Papillomaviruses Target the DNA Damage Repair and Innate Immune Response Pathways to Allow for Persistent Infection. Viruses. 13. PMID 34372596 DOI: 10.3390/v13071390  0.499
2021 Kaminski P, Hong S, Kono T, Hoover P, Laimins L. Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication. Mbio. 12. PMID 33563836 DOI: 10.1128/mBio.00005-21  0.729
2021 Mehta K, Laimins L. High-Risk Human Papillomaviruses and DNA Repair. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 217: 141-155. PMID 33200365 DOI: 10.1007/978-3-030-57362-1_7  0.745
2020 Hong S, Li Y, Kaminski PJ, Andrade J, Laimins LA. Pathogenesis of Human Papillomaviruses Requires the ATR/p62 Autophagy-Related Pathway. Mbio. 11. PMID 32788179 DOI: 10.1128/mBio.01628-20  0.758
2020 Albert E, Laimins L. Regulation of the Human Papillomavirus Life Cycle by DNA Damage Repair Pathways and Epigenetic Factors. Viruses. 12. PMID 32664381 DOI: 10.3390/V12070744  0.754
2020 Kono T, Hoover P, Poropatich K, Paunesku T, Mittal BB, Samant S, Laimins LA. Activation of DNA damage repair factors in HPV positive oropharyngeal cancers. Virology. 547: 27-34. PMID 32560902 DOI: 10.1016/j.virol.2020.05.003  0.741
2019 Zhao J, Lee EE, Kim J, Yang R, Chamseddin B, Ni C, Gusho E, Xie Y, Chiang CM, Buszczak M, Zhan X, Laimins L, Wang RC. Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus. Nature Communications. 10: 2300. PMID 31127091 DOI: 10.1038/S41467-019-10246-5  0.77
2019 Hong S, Xu J, Li Y, Andrade J, Hoover P, Kaminski PJ, Laimins LA. Topoisomerase IIβ-binding protein 1 activates expression of E2F1 and p73 in HPV-positive cells for genome amplification upon epithelial differentiation. Oncogene. PMID 30631149 DOI: 10.1038/s41388-018-0633-1  0.764
2018 Spriggs CC, Blanco LZ, Maniar KP, Laimins LA. Expression of HPV-induced DNA Damage Repair Factors Correlates With CIN Progression. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. PMID 29995652 DOI: 10.1097/PGP.0000000000000477  0.725
2018 Mehta K, Laimins L. Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification. Mbio. 9. PMID 29440569 DOI: 10.1128/Mbio.00064-18  0.728
2017 Hong S, Cheng S, Songock W, Bodily J, Laimins LA. Suppression of microRNA 424 levels by human papillomavirus proteins is necessary for differentiation-dependent genome amplification. Journal of Virology. PMID 28978708 DOI: 10.1128/Jvi.01712-17  0.86
2017 Spriggs CC, Laimins LA. Human Papillomavirus and the DNA Damage Response: Exploiting Host Repair Pathways for Viral Replication. Viruses. 9. PMID 28820495 DOI: 10.3390/v9080232  0.735
2017 Spriggs CC, Laimins LA. FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication. Mbio. 8. PMID 28196964 DOI: 10.1128/mBio.02340-16  0.76
2016 Hong S, Laimins LA. Manipulation of the innate immune response by human papillomaviruses. Virus Research. PMID 27826042 DOI: 10.1016/j.virusres.2016.11.004  0.717
2016 Langsfeld E, Laimins LA. Human papillomaviruses: research priorities for the next decade. Trends in Cancer. 2: 234-240. PMID 27617309 DOI: 10.1016/j.trecan.2016.04.001  0.398
2016 Gunasekharan VK, Li Y, Andrade J, Laimins LA. Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle. Plos Pathogens. 12: e1005747. PMID 27386862 DOI: 10.1371/journal.ppat.1005747  0.773
2016 Langsfeld E, Laimins LA. Human Papillomaviruses: Research Priorities for the Next Decade Trends in Cancer. 2: 234-240. DOI: 10.1016/j.trecan.2016.04.001  0.723
2015 Hong S, Cheng S, Iovane A, Laimins LA. STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication. Mbio. 6. PMID 26695634 DOI: 10.1128/Mbio.02006-15  0.759
2015 Langsfeld ES, Bodily JM, Laimins LA. The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replication by Modulating Histone Acetylation and Recruitment of DNA Damage Factors NBS1 and Rad51 to Viral Genomes. Plos Pathogens. 11: e1005181. PMID 26405826 DOI: 10.1371/Journal.Ppat.1005181  0.874
2015 Galloway DA, Laimins LA. Human papillomaviruses: shared and distinct pathways for pathogenesis. Current Opinion in Virology. 14: 87-92. PMID 26398222 DOI: 10.1016/J.Coviro.2015.09.001  0.714
2015 Mehta K, Gunasekharan V, Satsuka A, Laimins LA. Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators. Plos Pathogens. 11: e1004763. PMID 25875106 DOI: 10.1371/journal.ppat.1004763  0.753
2015 Hong S, Dutta A, Laimins LA. The acetyltransferase Tip60 is a critical regulator of the differentiation-dependent amplification of human papillomaviruses. Journal of Virology. 89: 4668-75. PMID 25673709 DOI: 10.1128/Jvi.03455-14  0.764
2015 Satsuka A, Mehta K, Laimins L. p38MAPK and MK2 pathways are important for the differentiation-dependent human papillomavirus life cycle. Journal of Virology. 89: 1919-24. PMID 25410865 DOI: 10.1128/Jvi.02712-14  0.756
2014 Pattabiraman C, Hong S, Gunasekharan VK, Pranatharthi A, Bajaj J, Srivastava S, Krishnamurthy H, Ammothumkandy A, Giri VG, Laimins LA, Krishna S. CD66+ cells in cervical precancers are partially differentiated progenitors with neoplastic traits. Cancer Research. 74: 6682-92. PMID 25267065 DOI: 10.1158/0008-5472.CAN-14-1032  0.582
2014 Kotnik Halavaty K, Regan J, Mehta K, Laimins L. Human papillomavirus E5 oncoproteins bind the A4 endoplasmic reticulum protein to regulate proliferative ability upon differentiation. Virology. 452: 223-30. PMID 24606699 DOI: 10.1016/J.Virol.2014.01.013  0.845
2014 Mighty KK, Laimins LA. The role of human papillomaviruses in oncogenesis. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 193: 135-48. PMID 24008297 DOI: 10.1007/978-3-642-38965-8_8  0.854
2013 Hong S, Laimins LA. Regulation of the life cycle of HPVs by differentiation and the DNA damage response. Future Microbiology. 8: 1547-57. PMID 24266355 DOI: 10.2217/fmb.13.127  0.752
2013 Hong S, Laimins LA. The JAK-STAT transcriptional regulator, STAT-5, activates the ATM DNA damage pathway to induce HPV 31 genome amplification upon epithelial differentiation. Plos Pathogens. 9: e1003295. PMID 23593005 DOI: 10.1371/journal.ppat.1003295  0.729
2013 Gunasekharan V, Laimins LA. Human papillomaviruses modulate microRNA 145 expression to directly control genome amplification. Journal of Virology. 87: 6037-43. PMID 23468503 DOI: 10.1128/JVI.00153-13  0.708
2013 Regan JA, Laimins LA. Viral transformation of epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 945: 449-65. PMID 23097122 DOI: 10.1007/978-1-62703-125-7_26  0.762
2013 Laimins LA. G102 Activation of differentiation-dependent human papillomavirus life cycle through the ATM DNA damage pathway Jaids Journal of Acquired Immune Deficiency Syndromes. 62: S58. DOI: 10.1097/01.qai.0000429255.00771.b4  0.58
2012 Donaldson MM, Mackintosh LJ, Bodily JM, Dornan ES, Laimins LA, Morgan IM. An interaction between human papillomavirus 16 E2 and TopBP1 is required for optimum viral DNA replication and episomal genome establishment. Journal of Virology. 86: 12806-15. PMID 22973044 DOI: 10.1128/Jvi.01002-12  0.833
2012 Gillespie KA, Mehta KP, Laimins LA, Moody CA. Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers. Journal of Virology. 86: 9520-6. PMID 22740399 DOI: 10.1128/JVI.00247-12  0.735
2012 Hoskins EE, Morreale RJ, Werner SP, Higginbotham JM, Laimins LA, Lambert PF, Brown DR, Gillison ML, Nuovo GJ, Witte DP, Kim MO, Davies SM, Mehta PA, Butsch Kovacic M, Wikenheiser-Brokamp KA, et al. The fanconi anemia pathway limits human papillomavirus replication. Journal of Virology. 86: 8131-8. PMID 22623785 DOI: 10.1128/Jvi.00408-12  0.764
2012 Gunasekharan V, Haché G, Laimins L. Differentiation-dependent changes in levels of C/EBPβ repressors and activators regulate human papillomavirus type 31 late gene expression. Journal of Virology. 86: 5393-8. PMID 22379085 DOI: 10.1128/JVI.07239-11  0.657
2011 Hong S, Mehta KP, Laimins LA. Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance. Journal of Virology. 85: 9486-94. PMID 21734056 DOI: 10.1128/JVI.05007-11  0.769
2011 Fradet-Turcotte A, Bergeron-Labrecque F, Moody CA, Lehoux M, Laimins LA, Archambault J. Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage response. Journal of Virology. 85: 8996-9012. PMID 21734051 DOI: 10.1128/Jvi.00542-11  0.691
2011 Mighty KK, Laimins LA. p63 is necessary for the activation of human papillomavirus late viral functions upon epithelial differentiation. Journal of Virology. 85: 8863-9. PMID 21715473 DOI: 10.1128/Jvi.00750-11  0.852
2011 Bodily JM, Mehta KP, Cruz L, Meyers C, Laimins LA. The E7 open reading frame acts in cis and in trans to mediate differentiation-dependent activities in the human papillomavirus type 16 life cycle. Journal of Virology. 85: 8852-62. PMID 21697473 DOI: 10.1128/Jvi.00664-11  0.867
2011 Knight GL, Pugh AG, Yates E, Bell I, Wilson R, Moody CA, Laimins LA, Roberts S. A cyclin-binding motif in human papillomavirus type 18 (HPV18) E1^E4 is necessary for association with CDK-cyclin complexes and G2/M cell cycle arrest of keratinocytes, but is not required for differentiation-dependent viral genome amplification or L1 capsid protein expression. Virology. 412: 196-210. PMID 21276999 DOI: 10.1016/J.Virol.2011.01.007  0.814
2011 Bodily JM, Mehta KP, Laimins LA. Human papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylases. Cancer Research. 71: 1187-95. PMID 21148070 DOI: 10.1158/0008-5472.Can-10-2626  0.862
2011 Bodily J, Laimins LA. Persistence of human papillomavirus infection: keys to malignant progression. Trends in Microbiology. 19: 33-9. PMID 21050765 DOI: 10.1016/J.Tim.2010.10.002  0.866
2010 Fradet-Turcotte A, Moody C, Laimins LA, Archambault J. Nuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance. Journal of Virology. 84: 11747-60. PMID 20844047 DOI: 10.1128/Jvi.01445-10  0.727
2010 Moody CA, Laimins LA. Human papillomavirus oncoproteins: pathways to transformation. Nature Reviews. Cancer. 10: 550-60. PMID 20592731 DOI: 10.1038/nrc2886  0.76
2010 Melar-New M, Laimins LA. Human papillomaviruses modulate expression of microRNA 203 upon epithelial differentiation to control levels of p63 proteins. Journal of Virology. 84: 5212-21. PMID 20219920 DOI: 10.1128/JVI.00078-10  0.716
2009 Moody CA, Laimins LA. Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation. Plos Pathogens. 5: e1000605. PMID 19798429 DOI: 10.1371/journal.ppat.1000605  0.772
2009 Beglin M, Melar-New M, Laimins L. Human papillomaviruses and the interferon response. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 29: 629-35. PMID 19715460 DOI: 10.1089/Jir.2009.0075  0.881
2009 Nakamura M, Bodily JM, Beglin M, Kyo S, Inoue M, Laimins LA. Hypoxia-specific stabilization of HIF-1alpha by human papillomaviruses. Virology. 387: 442-8. PMID 19321184 DOI: 10.1016/J.Virol.2009.02.036  0.835
2009 Moody CA, Laimins LA. The life cycle of human papillomaviruses Dna Tumor Viruses. 75-104. DOI: 10.1007/978-0-387-68945-6_4  0.7
2008 Regan JA, Laimins LA. Bap31 is a novel target of the human papillomavirus E5 protein. Journal of Virology. 82: 10042-51. PMID 18684816 DOI: 10.1128/Jvi.01240-08  0.86
2008 Wooldridge TR, Laimins LA. Regulation of human papillomavirus type 31 gene expression during the differentiation-dependent life cycle through histone modifications and transcription factor binding. Virology. 374: 371-80. PMID 18237759 DOI: 10.1016/j.virol.2007.12.011  0.644
2008 Côté-Martin A, Moody C, Fradet-Turcotte A, D'Abramo CM, Lehoux M, Joubert S, Poirier GG, Coulombe B, Laimins LA, Archambault J. Human papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes. Journal of Virology. 82: 1271-83. PMID 18032488 DOI: 10.1128/Jvi.01405-07  0.768
2007 Moody CA, Fradet-Turcotte A, Archambault J, Laimins LA. Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification. Proceedings of the National Academy of Sciences of the United States of America. 104: 19541-6. PMID 18048335 DOI: 10.1073/Pnas.0707947104  0.724
2007 Hebner C, Beglin M, Laimins LA. Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation. Journal of Virology. 81: 12740-7. PMID 17898049 DOI: 10.1128/Jvi.00987-07  0.846
2007 Hindmarsh PL, Laimins LA. Mechanisms regulating expression of the HPV 31 L1 and L2 capsid proteins and pseudovirion entry. Virology Journal. 4: 19. PMID 17324266 DOI: 10.1186/1743-422X-4-19  0.727
2007 Wilson R, Ryan GB, Knight GL, Laimins LA, Roberts S. The full-length E1E4 protein of human papillomavirus type 18 modulates differentiation-dependent viral DNA amplification and late gene expression. Virology. 362: 453-60. PMID 17303206 DOI: 10.1016/J.Virol.2007.01.005  0.822
2007 Sénéchal H, Poirier GG, Coulombe B, Laimins LA, Archambault J. Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4. Virology. 358: 10-7. PMID 17023018 DOI: 10.1016/J.Virol.2006.08.035  0.755
2007 Lee C, Wooldridge TR, Laimins LA. Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle. Virology. 358: 201-10. PMID 16999984 DOI: 10.1016/J.Virol.2006.08.028  0.823
2007 Lee C, Laimins LA. The differentiation-dependent life cycle of human papillomaviruses in keratinocytes The Papillomaviruses. 45-67. DOI: 10.1007/978-0-387-36523-7_4  0.554
2006 Cai X, Li G, Laimins LA, Cullen BR. Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication. Journal of Virology. 80: 10890-3. PMID 17041229 DOI: 10.1128/Jvi.01175-06  0.72
2006 Hebner CM, Wilson R, Rader J, Bidder M, Laimins LA. Human papillomaviruses target the double-stranded RNA protein kinase pathway. The Journal of General Virology. 87: 3183-93. PMID 17030851 DOI: 10.1099/Vir.0.82098-0  0.887
2006 Longworth MS, Laimins LA. Histone deacetylase 3 localizes to the plasma membrane and is a substrate of Src. Oncogene. 25: 4495-500. PMID 16532030 DOI: 10.1038/sj.onc.1209473  0.741
2006 Hebner CM, Laimins LA. Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity. Reviews in Medical Virology. 16: 83-97. PMID 16287204 DOI: 10.1002/Rmv.488  0.887
2005 Wilson R, Laimins LA. Differentiation of HPV-containing cells using organotypic "raft" culture or methylcellulose. Methods in Molecular Medicine. 119: 157-69. PMID 16350403 DOI: 10.1385/1-59259-982-6:157  0.796
2005 Wilson R, Fehrmann F, Laimins LA. Role of the E1--E4 protein in the differentiation-dependent life cycle of human papillomavirus type 31. Journal of Virology. 79: 6732-40. PMID 15890911 DOI: 10.1128/Jvi.79.11.6732-6740.2005  0.82
2005 Longworth MS, Wilson R, Laimins LA. HPV31 E7 facilitates replication by activating E2F2 transcription through its interaction with HDACs. The Embo Journal. 24: 1821-30. PMID 15861133 DOI: 10.1038/Sj.Emboj.7600651  0.874
2005 Spink KM, Laimins LA. Induction of the human papillomavirus type 31 late promoter requires differentiation but not DNA amplification. Journal of Virology. 79: 4918-26. PMID 15795277 DOI: 10.1128/JVI.79.8.4918-4926.2005  0.718
2005 Fehrmann F, Laimins LA. Human papillomavirus type 31 life cycle: methods for study using tissue culture models. Methods in Molecular Biology (Clifton, N.J.). 292: 317-30. PMID 15507718  0.747
2004 Lee C, Laimins LA. Role of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31. Journal of Virology. 78: 12366-77. PMID 15507623 DOI: 10.1128/Jvi.78.22.12366-12377.2004  0.822
2004 Longworth MS, Laimins LA. Pathogenesis of human papillomaviruses in differentiating epithelia. Microbiology and Molecular Biology Reviews : Mmbr. 68: 362-72. PMID 15187189 DOI: 10.1128/Mmbr.68.2.362-372.2004  0.874
2004 Longworth MS, Laimins LA. The binding of histone deacetylases and the integrity of zinc finger-like motifs of the E7 protein are essential for the life cycle of human papillomavirus type 31. Journal of Virology. 78: 3533-41. PMID 15016876 DOI: 10.1128/Jvi.78.7.3533-3541.2004  0.85
2004 Oh ST, Longworth MS, Laimins LA. Roles of the E6 and E7 proteins in the life cycle of low-risk human papillomavirus type 11. Journal of Virology. 78: 2620-6. PMID 14963169 DOI: 10.1128/Jvi.78.5.2620-2626.2004  0.874
2004 Laimins LA. Biology: Oncoproteins and malignancy Papillomavirus Report. 15: 107-108. DOI: 10.1179/095741904225004909  0.496
2003 Fehrmann F, Laimins LA. Human papillomaviruses: targeting differentiating epithelial cells for malignant transformation. Oncogene. 22: 5201-7. PMID 12910257 DOI: 10.1038/sj.onc.1206554  0.765
2003 Fehrmann F, Klumpp DJ, Laimins LA. Human papillomavirus type 31 E5 protein supports cell cycle progression and activates late viral functions upon epithelial differentiation. Journal of Virology. 77: 2819-31. PMID 12584305 DOI: 10.1128/JVI.77.5.2819-2831.2003  0.785
2002 Klimov E, Vinokourova S, Moisjak E, Rakhmanaliev E, Kobseva V, Laimins L, Kisseljov F, Sulimova G. Human papilloma viruses and cervical tumours: mapping of integration sites and analysis of adjacent cellular sequences. Bmc Cancer. 2: 24. PMID 12377107 DOI: 10.1186/1471-2407-2-24  0.732
2002 Chang YE, Pena L, Sen GC, Park JK, Laimins LA. Long-term effect of interferon on keratinocytes that maintain human papillomavirus type 31. Journal of Virology. 76: 8864-74. PMID 12163606 DOI: 10.1128/Jvi.76.17.8864-8874.2002  0.849
2002 Hubert WG, Laimins LA. Human papillomavirus type 31 replication modes during the early phases of the viral life cycle depend on transcriptional and posttranscriptional regulation of E1 and E2 expression. Journal of Virology. 76: 2263-73. PMID 11836404 DOI: 10.1128/jvi.76.5.2263-2273.2002  0.714
2002 Peña LdM, Laimins LA. Regulation of human papillomavirus gene expression in the vegetative life cycle Perspectives in Medical Virology. 8: 31-51.  0.598
2001 Chang YE, Laimins LA. Interferon-inducible genes are major targets of human papillomavirus type 31: insights from microarray analysis. Disease Markers. 17: 139-42. PMID 11790877  0.587
2001 del Mar Peña LM, Laimins LA. Differentiation-dependent chromatin rearrangement coincides with activation of human papillomavirus type 31 late gene expression. Journal of Virology. 75: 10005-13. PMID 11559836 DOI: 10.1128/JVI.75.20.10005-10013.2001  0.682
2001 Terhune SS, Hubert WG, Thomas JT, Laimins LA. Early polyadenylation signals of human papillomavirus type 31 negatively regulate capsid gene expression. Journal of Virology. 75: 8147-57. PMID 11483760 DOI: 10.1128/Jvi.75.17.8147-8157.2001  0.801
2001 Thomas JT, Oh ST, Terhune SS, Laimins LA. Cellular changes induced by low-risk human papillomavirus type 11 in keratinocytes that stably maintain viral episomes. Journal of Virology. 75: 7564-71. PMID 11462028 DOI: 10.1128/Jvi.75.16.7564-7571.2001  0.869
2001 Oh ST, Kyo S, Laimins LA. Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites. Journal of Virology. 75: 5559-66. PMID 11356963 DOI: 10.1128/Jvi.75.12.5559-5566.2001  0.753
2000 Chang YE, Laimins LA. Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31. Journal of Virology. 74: 4174-82. PMID 10756030 DOI: 10.1128/JVI.74.9.4174-4182.2000  0.714
2000 Stubenrauch F, Hummel M, Iftner T, Laimins LA. The E8E2C protein, a negative regulator of viral transcription and replication, is required for extrachromosomal maintenance of human papillomavirus type 31 in keratinocytes. Journal of Virology. 74: 1178-86. PMID 10627528 DOI: 10.1128/JVI.74.3.1178-1186.2000  0.789
1999 Stubenrauch F, Laimins LA. Human papillomavirus life cycle: active and latent phases. Seminars in Cancer Biology. 9: 379-86. PMID 10712884 DOI: 10.1006/scbi.1999.0141  0.756
1999 Terhune SS, Milcarek C, Laimins LA. Regulation of human papillomavirus type 31 polyadenylation during the differentiation-dependent life cycle. Journal of Virology. 73: 7185-92. PMID 10438805 DOI: 10.1128/Jvi.73.9.7185-7192.1999  0.815
1999 Thomas JT, Hubert WG, Ruesch MN, Laimins LA. Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes. Proceedings of the National Academy of Sciences of the United States of America. 96: 8449-54. PMID 10411895 DOI: 10.1073/pnas.96.15.8449  0.728
1999 Klumpp DJ, Laimins LA. Differentiation-induced changes in promoter usage for transcripts encoding the human papillomavirus type 31 replication protein E1. Virology. 257: 239-46. PMID 10208937 DOI: 10.1006/viro.1999.9636  0.785
1999 Hubert WG, Kanaya T, Laimins LA. DNA replication of human papillomavirus type 31 is modulated by elements of the upstream regulatory region that lie 5' of the minimal origin. Journal of Virology. 73: 1835-45. PMID 9971761  0.712
1998 Ruesch MN, Laimins LA. Human papillomavirus oncoproteins alter differentiation-dependent cell cycle exit on suspension in semisolid medium. Virology. 250: 19-29. PMID 9770416 DOI: 10.1006/viro.1998.9359  0.753
1998 Stubenrauch F, Colbert AM, Laimins LA. Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions. Journal of Virology. 72: 8115-23. PMID 9733852  0.792
1998 Ruesch MN, Stubenrauch F, Laimins LA. Activation of papillomavirus late gene transcription and genome amplification upon differentiation in semisolid medium is coincident with expression of involucrin and transglutaminase but not keratin-10. Journal of Virology. 72: 5016-24. PMID 9573271  0.782
1998 Thomas JT, Laimins LA. Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint. Journal of Virology. 72: 1131-7. PMID 9445009  0.693
1998 Stubenrauch F, Lim HB, Laimins LA. Differential requirements for conserved E2 binding sites in the life cycle of oncogenic human papillomavirus type 31. Journal of Virology. 72: 1071-7. PMID 9445001  0.777
1997 Kanaya T, Kyo S, Laimins LA. The 5' region of the human papillomavirus type 31 upstream regulatory region acts as an enhancer which augments viral early expression through the action of YY1. Virology. 237: 159-69. PMID 9344918 DOI: 10.1006/viro.1997.8771  0.663
1997 Klumpp DJ, Stubenrauch F, Laimins LA. Differential effects of the splice acceptor at nucleotide 3295 of human papillomavirus type 31 on stable and transient viral replication. Journal of Virology. 71: 8186-94. PMID 9343169  0.769
1997 Frattini MG, Lim HB, Doorbar J, Laimins LA. Induction of human papillomavirus type 18 late gene expression and genomic amplification in organotypic cultures from transfected DNA templates. Journal of Virology. 71: 7068-72. PMID 9261437 DOI: 10.1128/Jvi.71.9.7068-7072.1997  0.836
1997 Ruesch MN, Laimins LA. Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activity. Journal of Virology. 71: 5570-8. PMID 9188631  0.66
1997 Frattini MG, Hurst SD, Lim HB, Swaminathan S, Laimins LA. Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein. The Embo Journal. 16: 318-31. PMID 9029152 DOI: 10.1093/Emboj/16.2.318  0.814
1997 Kyo S, Klumpp DJ, Inoue M, Kanaya T, Laimins LA. Expression of AP1 during cellular differentiation determines human papillomavirus E6/E7 expression in stratified epithelial cells. The Journal of General Virology. 78: 401-11. PMID 9018063 DOI: 10.1099/0022-1317-78-2-401  0.73
1996 Grossman SR, Laimins LA. EBNA1 and E2: a new paradigm for origin-binding proteins? Trends in Microbiology. 4: 87-9. PMID 8868083 DOI: 10.1016/0966-842X(96)81520-4  0.716
1996 Frattini MG, Lim HB, Laimins LA. In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression. Proceedings of the National Academy of Sciences of the United States of America. 93: 3062-7. PMID 8610168 DOI: 10.1073/Pnas.93.7.3062  0.846
1996 McIntyre MC, Ruesch MN, Laimins LA. Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p107. Virology. 215: 73-82. PMID 8553588 DOI: 10.1006/viro.1996.0008  0.688
1996 Laimins LA. Human papillomaviruses target differentiating epithelia for virion production and malignant conversion Seminars in Virology. 7: 305-313. DOI: 10.1006/smvy.1996.0038  0.707
1996 Laimins LA. Introduction: Viruses in human cancers Seminars in Virology. 7: 293-294. DOI: 10.1006/smvy.1996.0036  0.526
1996 Monini P, Laimins LA. Modulation of epithelial differentiation by the E6 and E7 oncoproteins of human papillomaviruses Radiation Oncology Investigations. 3: 377-382.  0.829
1995 Comerford SA, Maika SD, Laimins LA, Messing A, Elsässer HP, Hammer RE. E6 and E7 expression from the HPV 18 LCR: development of genital hyperplasia and neoplasia in transgenic mice. Oncogene. 10: 587-97. PMID 7845684  0.703
1995 Pray TR, Laimins LA. Differentiation-dependent expression of E1--E4 proteins in cell lines maintaining episomes of human papillomavirus type 31b. Virology. 206: 679-85. PMID 7831825 DOI: 10.1016/S0042-6822(95)80088-3  0.82
1995 Hummel M, Lim HB, Laimins LA. Human papillomavirus type 31b late gene expression is regulated through protein kinase C-mediated changes in RNA processing. Journal of Virology. 69: 3381-8. PMID 7745684  0.666
1995 Kyo S, Tam A, Laimins LA. Transcriptional activity of human papillomavirus type 31b enhancer is regulated through synergistic interaction of AP1 with two novel cellular factors. Virology. 211: 184-97. PMID 7645210 DOI: 10.1006/viro.1995.1390  0.737
1994 Lechner MS, Laimins LA. Inhibition of p53 DNA binding by human papillomavirus E6 proteins. Journal of Virology. 68: 4262-73. PMID 8207801  0.717
1994 Meyers C, Laimins LA. In vitro systems for the study and propagation of human papillomaviruses. Current Topics in Microbiology and Immunology. 186: 199-215. PMID 8205842 DOI: 10.1007/978-3-642-78487-3_11  0.747
1994 Frattini MG, Laimins LA. The role of the E1 and E2 proteins in the replication of human papillomavirus type 31b. Virology. 204: 799-804. PMID 7941349 DOI: 10.1006/viro.1994.1596  0.821
1994 Frattini MG, Laimins LA. Binding of the human papillomavirus E1 origin-recognition protein is regulated through complex formation with the E2 enhancer-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 12398-402. PMID 7809048 DOI: 10.1073/Pnas.91.26.12398  0.766
1993 McIntyre MC, Frattini MG, Grossman SR, Laimins LA. Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding. Journal of Virology. 67: 3142-50. PMID 8497045  0.841
1993 De Geest K, Turyk ME, Hosken MI, Hudson JB, Laimins LA, Wilbanks GD. Growth and differentiation of human papillomavirus type 31b positive human cervical cell lines. Gynecologic Oncology. 49: 303-10. PMID 8390960 DOI: 10.1006/gyno.1993.1131  0.722
1993 Mack DH, Vartikar J, Pipas JM, Laimins LA. Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53. Nature. 363: 281-3. PMID 8387645 DOI: 10.1038/363281A0  0.579
1993 Wagner AJ, Meyers C, Laimins LA, Hay N. c-Myc induces the expression and activity of ornithine decarboxylase. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 4: 879-83. PMID 8297793  0.557
1993 Laimins LA. The biology of human papillomaviruses: from warts to cancer. Infectious Agents and Disease. 2: 74-86. PMID 8162357  0.727
1992 Lechner MS, Mack DH, Finicle AB, Crook T, Vousden KH, Laimins LA. Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription. The Embo Journal. 11: 3045-52. PMID 1379175  0.705
1992 Hegde RS, Grossman SR, Laimins LA, Sigler PB. Crystal structure at 1.7 A of the bovine papillomavirus-1 E2 DNA-binding domain bound to its DNA target. Nature. 359: 505-12. PMID 1328886 DOI: 10.1038/359505A0  0.697
1992 Hummel M, Hudson JB, Laimins LA. Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes. Journal of Virology. 66: 6070-80. PMID 1326657  0.731
1992 Meyers C, Frattini MG, Hudson JB, Laimins LA. Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation. Science (New York, N.Y.). 257: 971-3. PMID 1323879 DOI: 10.1126/Science.1323879  0.826
1992 Prakash SS, Grossman SR, Pepinsky RB, Laimins LA, Androphy EJ. Amino acids necessary for DNA contact and dimerization imply novel motifs in the papillomavirus E2 trans-activator. Genes & Development. 6: 105-16. PMID 1309714  0.71
1992 Lechner MS, Mack DH, Finicle AB, Crook T, Vousden KH, Laimins LA. Corrigendum: Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription (The EMBO Journal(1992)11(3045-3052)) Embo Journal. 11: 4248.  0.331
1991 Bedell MA, Hudson JB, Golub TR, Turyk ME, Hosken M, Wilbanks GD, Laimins LA. Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation. Journal of Virology. 65: 2254-60. PMID 1850010 DOI: 10.1128/Jvi.65.5.2254-2260.1991  0.868
1991 Monini P, Grossman SR, Pepinsky B, Androphy EJ, Laimins LA. Cooperative binding of the E2 protein of bovine papillomavirus to adjacent E2-responsive sequences. Journal of Virology. 65: 2124-30. PMID 1848322  0.79
1991 Blitz IL, Laimins LA. The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro Journal of Virology. 65: 649-656. PMID 1846189 DOI: 10.1128/Jvi.65.2.649-656.1991  0.809
1991 Lechner MS, Laimins LA. Human epithelial cells immortalized by SV40 retain differentiation capabilities in an in vitro raft system and maintain viral DNA extrachromosomally. Virology. 185: 563-71. PMID 1660195 DOI: 10.1016/0042-6822(91)90526-H  0.6
1991 Park JS, Rader JS, Wu TC, Laimins LA, Currie JL, Kurman RJ, Shah KV. HPV-16 viral transcripts in vulvar neoplasia: preliminary studies. Gynecologic Oncology. 42: 250-5. PMID 1659554 DOI: 10.1016/0090-8258(91)90354-8  0.729
1991 Mack DH, Laimins LA. A keratinocyte-specific transcription factor, KRF-1, interacts with AP-1 to activate expression of human papillomavirus type 18 in squamous epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 9102-6. PMID 1656460  0.717
1991 Rader JS, Rosenzweig BA, Spirtas R, Padleckas R, Javaheri G, Gerardo L, Laimins LA. Atypical squamous cells. A case-series study of the association between papanicolaou smear results and human papillomavirus DNA genotype. The Journal of Reproductive Medicine. 36: 291-7. PMID 1649307  0.707
1991 Rader J, Park J, Wu T, Shah K, Kurman R, Laimins L, Currie J. 3H-labeled subgenomic mRNA probes can demonstrate subtle differences in human papilloma virus expression in preinvasive and invasive vulvar cancers Gynecologic Oncology. 40: 184-185. DOI: 10.1016/0090-8258(91)90183-6  0.536
1991 Wilbanks G, Turyk M, Hosken M, Bedell M, Hudson J, Golub T, Laimins L. Identification of HPV 31B in human cervical cells grown on raised collagen gel rafts Gynecologic Oncology. 40: 184. DOI: 10.1016/0090-8258(91)90182-5  0.85
1990 Hudson JB, Bedell MA, Mccance DJ, Laimins LA. Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18 Journal of Virology. 64: 519-526. PMID 2153221 DOI: 10.1128/Jvi.64.2.519-526.1990  0.784
1990 Rader JS, Golub TR, Hudson JB, Patel D, Bedell MA, Laimins LA. In vitro differentiation of epithelial cells from cervical neoplasias resembles in vivo lesions. Oncogene. 5: 571-6. PMID 1691480  0.442
1989 Bedell MA, Jones KH, Grossman SR, Laimins LA. Identification of human papillomavirus type 18 transforming genes in immortalized and primary cells Journal of Virology. 63: 1247-1255. PMID 2536832 DOI: 10.1128/Jvi.63.3.1247-1255.1989  0.879
1989 Gius D, Laimins LA. Activation of human papillomavirus type 18 gene expression by herpes simplex virus type 1 viral transactivators and a phorbol ester Journal of Virology. 63: 555-563. PMID 2536091  0.749
1989 Grossman SR, Mora R, Laimins LA. Intracellular localization and DNA-binding properties of human papillomavirus type 18 E6 protein expressed with a baculovirus vector Journal of Virology. 63: 366-374. PMID 2535738  0.813
1989 Rosenzweig B, Rader J, Padleckas R, Javaheri G, Gerardo L, Laimins L. Correlation of human papillomavirus DNA type and presence of atypical squamous cells in Pap smears Gynecologic Oncology. 32: 115. DOI: 10.1016/0090-8258(89)90949-9  0.624
1988 Gius D, Grossman S, Bedell MA, Laimins LA. Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18 Journal of Virology. 62: 665-672. PMID 2828662  0.863
1988 McCance DJ, Kopan R, Fuchs E, Laimins LA. Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. Proceedings of the National Academy of Sciences of the United States of America. 85: 7169-73. PMID 2459699 DOI: 10.1073/Pnas.85.19.7169  0.745
1987 Bedell MA, Jones KH, Laimins LA. The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells Journal of Virology. 61: 3635-3640. PMID 2822969 DOI: 10.1128/Jvi.61.11.3635-3640.1987  0.819
1986 Laimins L, Holmgren-Konig M, Khoury G. Transcriptional 'silencer' element in rat repetitive sequences associated with the rat insulin 1 gene locus Proceedings of the National Academy of Sciences of the United States of America. 83: 3151-3155. PMID 3010279 DOI: 10.1073/Pnas.83.10.3151  0.692
1985 Lakshmikumaran MS, D'Ambrosio E, Laimins LA, Lin DT, Furano AV. Long interspersed repeated DNA (LINE) causes polymorphism at the rat insulin 1 locus. Molecular and Cellular Biology. 5: 2197-203. PMID 3016521  0.496
1984 Laimins LA, Gruss P, Pozzatti R, Khoury G. Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus. Journal of Virology. 49: 183-9. PMID 6690710 DOI: 10.1128/Jvi.49.1.183-189.1984  0.734
1984 Laimins LA, Tsichlis P, Khoury G. Multiple enhancer domains in the 3′ terminus of the prague strain of rous sarcoma virus Nucleic Acids Research. 12: 6427-6442. PMID 6089114 DOI: 10.1093/Nar/12.16.6427  0.674
1982 Laimins LA, Khoury G, Gorman C, Howard B, Gruss P. Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus Proceedings of the National Academy of Sciences of the United States of America. 79: 6453-6457. PMID 6292901 DOI: 10.1073/Pnas.79.21.6453  0.758
1981 Laimins LA, Rhoads DB, Epstein W. Osmotic control of kdp operon expression in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 78: 464-8. PMID 6787588 DOI: 10.1073/Pnas.78.1.464  0.693
1980 Epstein W, Laimins L. Potassium transport in Escherichia coli: diverse systems with common control by osmotic forces Trends in Biochemical Sciences. 5: 21-23. DOI: 10.1016/S0968-0004(80)80072-7  0.692
1978 Laimins LA, Rhoads DB, Altendorf K, Epstein W. Identification of the structural proteins of an ATP-driven potassium transport system in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 75: 3216-9. PMID 356049 DOI: 10.1073/Pnas.75.7.3216  0.707
1978 Rhoads DB, Laimins L, Epstein W. Functional organization of the kdp genes of Escherichia coli K-12. Journal of Bacteriology. 135: 445-52. PMID 355227 DOI: 10.1128/Jb.135.2.445-452.1978  0.701
1973 Ekin JW, Laimins LA, Serin B. Observations associated with non-linear voltage-current characteristics of type II superconductors Solid State Communications. 13: 1681-1683. DOI: 10.1016/0038-1098(73)90265-2  0.459
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