Lori Frappier - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Microbiology Biology

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 De La Cruz-Herrera CF, Tatham MH, Siddiqi UZ, Shire K, Marcon E, Greenblatt JF, Hay RT, Frappier L. Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1. Plos Pathogens. 19: e1011477. PMID 37410772 DOI: 10.1371/journal.ppat.1011477  0.405
2022 Yockteng-Melgar J, Shire K, Cheng AZ, Malik-Soni N, Harris RS, Frappier L. G/S Cell Cycle Induction by Epstein-Barr Virus BORF2 Is Mediated by P53 and APOBEC3B. Journal of Virology. e0066022. PMID 36069545 DOI: 10.1128/jvi.00660-22  0.371
2022 Airo AM, Felix-Lopez A, Mancinelli V, Evseev D, Lopez-Orozco J, Shire K, Paszkowski P, Frappier L, Magor KE, Hobman TC. Flavivirus Capsid Proteins Inhibit the Interferon Response. Viruses. 14. PMID 35632712 DOI: 10.3390/v14050968  0.409
2021 Shire K, Marcon E, Greenblatt J, Frappier L. Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3. Virology. 562: 103-109. PMID 34304093 DOI: 10.1016/j.virol.2021.07.009  0.369
2019 Cheng AZ, Nóbrega de Moraes S, Attarian C, Yockteng-Melgar J, Jarvis MC, Biolatti M, Galitska G, Dell'Oste V, Frappier L, Bierle CJ, Rice SA, Harris RS. A Conserved Mechanism of APOBEC3 Relocalization by Herpesviral Ribonucleotide Reductase Large Subunits. Journal of Virology. PMID 31534038 DOI: 10.1128/Jvi.01539-19  0.502
2019 Salamun SG, Sitz J, De La Cruz-Herrera CF, Yockteng-Melgar J, Marcon E, Greenblatt J, Fradet-Turcotte A, Frappier L. The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD. Journal of Virology. PMID 31462557 DOI: 10.1128/Jvi.01070-19  0.567
2019 Siddiqi UZ, Vaidya AS, Li X, Marcon E, Tsao SW, Greenblatt J, Frappier L. Identification of ARKL1 as a Negative Regulator of Epstein-Barr Virus Reactivation. Journal of Virology. PMID 31341047 DOI: 10.1128/Jvi.00989-19  0.539
2019 Georges A, Coyaud E, Marcon E, Greenblatt J, Raught B, Frappier L. USP7 Regulates Cytokinesis through FBXO38 and KIF20B. Scientific Reports. 9: 2724. PMID 30804394 DOI: 10.1038/S41598-019-39368-Y  0.469
2019 Frappier L. Epstein–Barr virus: overcoming the DNA damage response Future Virology. 14: 349-360. DOI: 10.2217/Fvl-2019-0015  0.408
2018 Cheng AZ, Yockteng-Melgar J, Jarvis MC, Malik-Soni N, Borozan I, Carpenter MA, McCann JL, Ebrahimi D, Shaban NM, Marcon E, Greenblatt J, Brown WL, Frappier L, Harris RS. Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity. Nature Microbiology. PMID 30420783 DOI: 10.1038/S41564-018-0284-6  0.529
2018 Georges A, Marcon E, Greenblatt J, Frappier L. Identification and Characterization of USP7 Targets in Cancer Cells. Scientific Reports. 8: 15833. PMID 30367141 DOI: 10.1038/S41598-018-34197-X  0.475
2018 De La Cruz-Herrera CF, Shire K, Siddiqi UZ, Frappier L. A genome-wide screen of Epstein-Barr virus proteins that modulate host SUMOylation identifies a SUMO E3 ligase conserved in herpesviruses. Plos Pathogens. 14: e1007176. PMID 29979787 DOI: 10.1371/Journal.Ppat.1007176  0.568
2018 Ho TH, Sitz J, Shen Q, Leblanc-Lacroix A, Campos EI, Borozan I, Marcon E, Greenblatt J, Fradet-Turcotte A, Jin DY, Frappier L. A Screen for Epstein-Barr Virus Proteins that Inhibit the DNA Damage Response Reveals a Novel Histone Binding Protein. Journal of Virology. PMID 29743367 DOI: 10.1128/Jvi.00262-18  0.539
2018 Borozan I, Zapatka M, Frappier L, Ferretti V. Correction for Borozan et al., "Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma". Journal of Virology. 92. PMID 29703776 DOI: 10.1128/Jvi.00330-18  0.303
2018 Airo AM, Urbanowski MD, Lopez-Orozco J, You JH, Skene-Arnold TD, Holmes C, Yamshchikov V, Malik-Soni N, Frappier L, Hobman TC. Expression of flavivirus capsids enhance the cellular environment for viral replication by activating Akt-signalling pathways. Virology. 516: 147-157. PMID 29358114 DOI: 10.1016/J.Virol.2018.01.009  0.465
2017 Borozan I, Zapatka M, Frappier L, Ferretti V. Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma. Journal of Virology. PMID 29093097 DOI: 10.1128/Jvi.01239-17  0.407
2017 Georges AA, Frappier L. Affinity Purification-Mass Spectroscopy Methods for Identifying Epstein-Barr Virus-Host Interactions. Methods in Molecular Biology (Clifton, N.J.). 1532: 79-92. PMID 27873268 DOI: 10.1007/978-1-4939-6655-4_5  0.458
2015 Shire K, Wong AI, Tatham MH, Anderson OF, Ripsman D, Gulstene S, Moffat J, Hay RT, Frappier L. Identification of RNF168 as a PML nuclear body regulator. Journal of Cell Science. PMID 26675234 DOI: 10.1242/Jcs.176446  0.476
2015 Frappier L. EBNA1. Current Topics in Microbiology and Immunology. 391: 3-34. PMID 26428370 DOI: 10.1007/978-3-319-22834-1_1  0.445
2015 You J, Hou S, Malik-Soni N, Xu Z, Kumar A, Rachubinski RA, Frappier L, Hobman TC. Flavivirus infection impairs peroxisome biogenesis and early anti-viral signaling. Journal of Virology. PMID 26423946 DOI: 10.1128/Jvi.01365-15  0.49
2015 Malik-Soni N, Frappier L. Correction for Malik-Soni and Frappier, Proteomic Profiling of EBNA1-Host Protein Interactions in Latent and Lytic Epstein-Barr Virus Infections. Journal of Virology. 89: 9143. PMID 26240277 DOI: 10.1128/Jvi.01581-15  0.48
2015 Marcon E, Jain H, Bhattacharya A, Guo H, Phanse S, Pu S, Byram G, Collins BC, Dowdell E, Fenner M, Guo X, Hutchinson A, Kennedy JJ, Krastins B, Larsen B, ... ... Frappier L, et al. Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation. Nature Methods. PMID 26121405 DOI: 10.1038/Nmeth.3472  0.318
2015 Pfoh R, Lacdao IK, Georges AA, Capar A, Zheng H, Frappier L, Saridakis V. Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7. Plos Pathogens. 11: e1004950. PMID 26046769 DOI: 10.1371/Journal.Ppat.1004950  0.54
2015 Georges AA, Frappier L. Proteomics methods for discovering viral-host interactions. Methods (San Diego, Calif.). 90: 21-7. PMID 25959231 DOI: 10.1016/J.Ymeth.2015.05.001  0.493
2015 Frappier L. Regulation of herpesvirus reactivation by host microRNAs. Journal of Virology. 89: 2456-8. PMID 25540363 DOI: 10.1128/Jvi.03413-14  0.374
2014 Mansouri S, Pan Q, Blencowe BJ, Claycomb JM, Frappier L. Epstein-Barr virus EBNA1 protein regulates viral latency through effects on let-7 microRNA and dicer. Journal of Virology. 88: 11166-77. PMID 25031339 DOI: 10.1128/Jvi.01785-14  0.387
2014 Paladino P, Marcon E, Greenblatt J, Frappier L. Identification of herpesvirus proteins that contribute to G1/S arrest. Journal of Virology. 88: 4480-92. PMID 24501404 DOI: 10.1128/Jvi.00059-14  0.511
2014 Malik-Soni N, Frappier L. Nucleophosmin contributes to the transcriptional activation function of the Epstein-Barr virus EBNA1 protein. Journal of Virology. 88: 2323-6. PMID 24284322 DOI: 10.1128/Jvi.02521-13  0.536
2014 Cao JY, Shire K, Landry C, Gish GD, Pawson T, Frappier L. Identification of a novel protein interaction motif in the regulatory subunit of casein kinase 2. Molecular and Cellular Biology. 34: 246-58. PMID 24216761 DOI: 10.1128/Mcb.00968-13  0.53
2014 Jagannathan M, Nguyen T, Gallo D, Luthra N, Brown GW, Saridakis V, Frappier L. A role for USP7 in DNA replication. Molecular and Cellular Biology. 34: 132-45. PMID 24190967 DOI: 10.1128/Mcb.00639-13  0.728
2013 Frappier L. A cancer-associated Epstein-Barr virus variant with epithelial tropism. Trends in Microbiology. 21: 616-7. PMID 24183509 DOI: 10.1016/J.Tim.2013.10.007  0.41
2013 Mansouri S, Wang S, Frappier L. A role for the nucleosome assembly proteins TAF-Iβ and NAP1 in the activation of BZLF1 expression and Epstein-Barr virus reactivation. Plos One. 8: e63802. PMID 23691099 DOI: 10.1371/Journal.Pone.0063802  0.502
2013 Sarkari F, Wheaton K, La Delfa A, Mohamed M, Shaikh F, Khatun R, Arrowsmith CH, Frappier L, Saridakis V, Sheng Y. Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. The Journal of Biological Chemistry. 288: 16975-85. PMID 23603909 DOI: 10.1074/Jbc.M113.469262  0.419
2012 Frappier L. The Epstein-Barr Virus EBNA1 Protein. Scientifica. 2012: 438204. PMID 24278697 DOI: 10.6064/2012/438204  0.382
2012 Frappier L. Contributions of Epstein-Barr nuclear antigen 1 (EBNA1) to cell immortalization and survival. Viruses. 4: 1537-47. PMID 23170171 DOI: 10.3390/V4091537  0.54
2012 Frappier L. EBNA1 and host factors in Epstein-Barr virus latent DNA replication. Current Opinion in Virology. 2: 733-9. PMID 23031715 DOI: 10.1016/J.Coviro.2012.09.005  0.549
2012 Nguyen T, Jagannathan M, Shire K, Frappier L. Interactions of the human MCM-BP protein with MCM complex components and Dbf4. Plos One. 7: e35931. PMID 22540012 DOI: 10.1371/Journal.Pone.0035931  0.725
2012 Malik-Soni N, Frappier L. Proteomic profiling of EBNA1-host protein interactions in latent and lytic Epstein-Barr virus infections. Journal of Virology. 86: 6999-7002. PMID 22496234 DOI: 10.1128/Jvi.00194-12  0.503
2012 Sivachandran N, Wang X, Frappier L. Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection. Journal of Virology. 86: 6146-58. PMID 22491455 DOI: 10.1128/Jvi.00013-12  0.79
2012 Jagannathan M, Sakwe AM, Nguyen T, Frappier L. The MCM-associated protein MCM-BP is important for human nuclear morphology. Journal of Cell Science. 125: 133-43. PMID 22250201 DOI: 10.1242/Jcs.089938  0.736
2012 Frappier L. Role of EBNA1 in NPC tumourigenesis. Seminars in Cancer Biology. 22: 154-61. PMID 22206863 DOI: 10.1016/J.Semcancer.2011.12.002  0.56
2012 Salsman J, Jagannathan M, Paladino P, Chan PK, Dellaire G, Raught B, Frappier L. Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response. Journal of Virology. 86: 806-20. PMID 22072767 DOI: 10.1128/Jvi.05442-11  0.742
2012 Cao JY, Mansouri S, Frappier L. Changes in the nasopharyngeal carcinoma nuclear proteome induced by the EBNA1 protein of Epstein-Barr virus reveal potential roles for EBNA1 in metastasis and oxidative stress responses. Journal of Virology. 86: 382-94. PMID 22013061 DOI: 10.1128/Jvi.05648-11  0.473
2012 Sivachandran N, Dawson CW, Young LS, Liu FF, Middeldorp J, Frappier L. Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinoma. Journal of Virology. 86: 60-8. PMID 22013060 DOI: 10.1128/Jvi.05623-11  0.799
2012 Frappier L. Promyelocytic leukemia nuclear body disruption as a treatment for EBV-associated nasopharyngeal carcinoma? Future Virology. 7: 1-3. DOI: 10.2217/Fvl.11.121  0.303
2011 Sivachandran N, Thawe NN, Frappier L. Epstein-Barr virus nuclear antigen 1 replication and segregation functions in nasopharyngeal carcinoma cell lines. Journal of Virology. 85: 10425-30. PMID 21795327 DOI: 10.1128/Jvi.05293-11  0.788
2011 Salsman J, Wang X, Frappier L. Nuclear body formation and PML body remodeling by the human cytomegalovirus protein UL35. Virology. 414: 119-29. PMID 21489587 DOI: 10.1016/J.Virol.2011.03.013  0.439
2011 Frappier L, Verrijzer CP. Gene expression control by protein deubiquitinases. Current Opinion in Genetics & Development. 21: 207-13. PMID 21411309 DOI: 10.1016/J.Gde.2011.02.005  0.374
2011 Sarkari F, Wang X, Nguyen T, Frappier L. The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies. Plos One. 6: e16598. PMID 21305000 DOI: 10.1371/Journal.Pone.0016598  0.526
2011 Welcker M, Larimore EA, Frappier L, Clurman BE. Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3. Molecular and Cellular Biology. 31: 1214-24. PMID 21220517 DOI: 10.1128/Mcb.01347-10  0.446
2011 Frappier L. Viral disruption of promyelocytic leukemia (PML) nuclear bodies by hijacking host PML regulators. Virulence. 2: 58-62. PMID 21217204 DOI: 10.4161/Viru.2.1.14610  0.578
2011 Nishiyama A, Frappier L, Méchali M. MCM-BP regulates unloading of the MCM2-7 helicase in late S phase. Genes & Development. 25: 165-75. PMID 21196493 DOI: 10.1101/gad.614411  0.322
2010 Sarkari F, Sheng Y, Frappier L. USP7/HAUSP promotes the sequence-specific DNA binding activity of p53. Plos One. 5: e13040. PMID 20885946 DOI: 10.1371/Journal.Pone.0013040  0.464
2010 Sivachandran N, Cao JY, Frappier L. Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodies. Journal of Virology. 84: 11113-23. PMID 20719947 DOI: 10.1128/Jvi.01183-10  0.822
2010 Sarkari F, La Delfa A, Arrowsmith CH, Frappier L, Sheng Y, Saridakis V. Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7. Journal of Molecular Biology. 402: 825-37. PMID 20713061 DOI: 10.1016/J.Jmb.2010.08.017  0.412
2009 Nayyar VK, Shire K, Frappier L. Mitotic chromosome interactions of Epstein-Barr nuclear antigen 1 (EBNA1) and human EBNA1-binding protein 2 (EBP2). Journal of Cell Science. 122: 4341-50. PMID 19887584 DOI: 10.1242/Jcs.060913  0.382
2009 Sarkari F, Sanchez-Alcaraz T, Wang S, Holowaty MN, Sheng Y, Frappier L. EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication. Plos Pathogens. 5: e1000624. PMID 19834552 DOI: 10.1371/Journal.Ppat.1000624  0.806
2009 Wang S, Frappier L. Nucleosome assembly proteins bind to Epstein-Barr virus nuclear antigen 1 and affect its functions in DNA replication and transcriptional activation. Journal of Virology. 83: 11704-14. PMID 19726498 DOI: 10.1128/Jvi.00931-09  0.583
2009 Cochrane A, Murley LL, Gao M, Wong R, Clayton K, Brufatto N, Canadien V, Mamelak D, Chen T, Richards D, Zeghouf M, Greenblatt J, Burks C, Frappier L. Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function. Virology. 388: 103-11. PMID 19339032 DOI: 10.1016/J.Virol.2009.03.005  0.413
2008 Lin A, Wang S, Nguyen T, Shire K, Frappier L. The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. Journal of Virology. 82: 12009-19. PMID 18922874 DOI: 10.1128/Jvi.01680-08  0.561
2008 Sivachandran N, Sarkari F, Frappier L. Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies. Plos Pathogens. 4: e1000170. PMID 18833293 DOI: 10.1371/Journal.Ppat.1000170  0.815
2008 Salsman J, Zimmerman N, Chen T, Domagala M, Frappier L. Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. Plos Pathogens. 4: e1000100. PMID 18617993 DOI: 10.1371/Journal.Ppat.1000100  0.524
2008 Freire E, Oddo C, Frappier L, de Prat-Gay G. Kinetically driven refolding of the hyperstable EBNA1 origin DNA-binding dimeric beta-barrel domain into amyloid-like spherical oligomers. Proteins. 70: 450-61. PMID 17680697 DOI: 10.1002/Prot.21580  0.533
2007 Maxwell KL, Frappier L. Viral proteomics. Microbiology and Molecular Biology Reviews : Mmbr. 71: 398-411. PMID 17554050 DOI: 10.1128/MMBR.00042-06  0.417
2007 Sakwe AM, Nguyen T, Athanasopoulos V, Shire K, Frappier L. Identification and characterization of a novel component of the human minichromosome maintenance complex. Molecular and Cellular Biology. 27: 3044-55. PMID 17296731 DOI: 10.1128/Mcb.02384-06  0.457
2006 Oddo C, Freire E, Frappier L, de Prat-Gay G. Mechanism of DNA recognition at a viral replication origin. The Journal of Biological Chemistry. 281: 26893-903. PMID 16815848 DOI: 10.1074/Jbc.M602083200  0.498
2006 Hegde NR, Chevalier MS, Wisner TW, Denton MC, Shire K, Frappier L, Johnson DC. The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins. The Journal of Biological Chemistry. 281: 20910-9. PMID 16731524 DOI: 10.1074/Jbc.M602989200  0.36
2006 Shire K, Kapoor P, Jiang K, Hing MN, Sivachandran N, Nguyen T, Frappier L. Regulation of the EBNA1 Epstein-Barr virus protein by serine phosphorylation and arginine methylation. Journal of Virology. 80: 5261-72. PMID 16699006 DOI: 10.1128/Jvi.02682-05  0.781
2006 Sheng Y, Saridakis V, Sarkari F, Duan S, Wu T, Arrowsmith CH, Frappier L. Molecular recognition of p53 and MDM2 by USP7/HAUSP. Nature Structural & Molecular Biology. 13: 285-91. PMID 16474402 DOI: 10.1038/Nsmb1067  0.383
2005 Gao M, Brufatto N, Chen T, Murley LL, Thalakada R, Domagala M, Beattie B, Mamelak D, Athanasopoulos V, Johnson D, McFadden G, Burks C, Frappier L. Expression profiling of herpesvirus and vaccinia virus proteins using a high-throughput baculovirus screening system. Journal of Proteome Research. 4: 2225-35. PMID 16335970 DOI: 10.1021/Pr050137U  0.442
2005 Kapoor P, Lavoie BD, Frappier L. EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases. Molecular and Cellular Biology. 25: 4934-45. PMID 15923612 DOI: 10.1128/Mcb.25.12.4934-4945.2005  0.488
2005 Saridakis V, Sheng Y, Sarkari F, Holowaty MN, Shire K, Nguyen T, Zhang RG, Liao J, Lee W, Edwards AM, Arrowsmith CH, Frappier L. Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Molecular Cell. 18: 25-36. PMID 15808506 DOI: 10.1016/J.Molcel.2005.02.029  0.784
2005 Kapoor P, Frappier L. Methods for measuring the replication and segregation of Epstein-Barr virus-based plasmids. Methods in Molecular Biology (Clifton, N.J.). 292: 247-66. PMID 15507713 DOI: 10.1385/1-59259-848-X:247  0.507
2004 Holowaty MN, Frappier L. HAUSP/USP7 as an Epstein-Barr virus target. Biochemical Society Transactions. 32: 731-2. PMID 15494000 DOI: 10.1042/Bst0320731  0.798
2003 Avolio-Hunter TM, Frappier L. EBNA1 efficiently assembles on chromatin containing the Epstein-Barr virus latent origin of replication. Virology. 315: 398-408. PMID 14585343 DOI: 10.1016/S0042-6822(03)00561-0  0.521
2003 Holowaty MN, Sheng Y, Nguyen T, Arrowsmith C, Frappier L. Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. The Journal of Biological Chemistry. 278: 47753-61. PMID 14506283 DOI: 10.1074/Jbc.M307200200  0.774
2003 Holowaty MN, Zeghouf M, Wu H, Tellam J, Athanasopoulos V, Greenblatt J, Frappier L. Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. The Journal of Biological Chemistry. 278: 29987-94. PMID 12783858 DOI: 10.1074/Jbc.M303977200  0.814
2003 Kapoor P, Frappier L. EBNA1 partitions Epstein-Barr virus plasmids in yeast cells by attaching to human EBNA1-binding protein 2 on mitotic chromosomes. Journal of Virology. 77: 6946-56. PMID 12768013 DOI: 10.1128/Jvi.77.12.6946-6956.2003  0.445
2002 Wu H, Kapoor P, Frappier L. Separation of the DNA replication, segregation, and transcriptional activation functions of Epstein-Barr nuclear antigen 1. Journal of Virology. 76: 2480-90. PMID 11836426 DOI: 10.1128/Jvi.76.5.2480-2490.2002  0.5
2001 Avolio-Hunter TM, Lewis PN, Frappier L. Epstein-Barr nuclear antigen 1 binds and destabilizes nucleosomes at the viral origin of latent DNA replication Nucleic Acids Research. 29: 3520-3528. PMID 11522821 DOI: 10.1093/Nar/29.17.3520  0.526
2001 Kapoor P, Shire K, Frappier L. Reconstitution of Epstein-Barr virus-based plasmid partitioning in budding yeast Embo Journal. 20: 222-230. PMID 11226172 DOI: 10.1093/Emboj/20.1.222  0.537
2000 Wu H, Ceccarelli DFJ, Frappier L. The DNA segregation mechanism of Epstein-Barr virus nuclear antigen 1 Embo Reports. 1: 140-144. PMID 11265753 DOI: 10.1093/Embo-Reports/Kvd026  0.501
2000 Mer G, Bochkarev A, Gupta R, Bochkareva E, Frappier L, Ingles CJ, Edwards AM, Chazin WJ. Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA Cell. 103: 449-456. PMID 11081631 DOI: 10.1016/S0092-8674(00)00136-7  0.448
2000 Huber MD, Dworet JH, Shire K, Frappier L, McAlear MA. The budding yeast homolog of the human EBNA1-binding protein 2 (Ebp2p) is an essential nucleolar protein required for pre-rRNA processing. The Journal of Biological Chemistry. 275: 28764-73. PMID 10849420 DOI: 10.1074/Jbc.M000594200  0.456
2000 Cruickshank J, Shire K, Davidson AR, Edwards AM, Frappier L. Two domains of the Epstein-Barr virus origin DNA-binding protein, EBNA1, orchestrate sequence-specific DNA binding Journal of Biological Chemistry. 275: 22273-22277. PMID 10801810 DOI: 10.1074/Jbc.M001414200  0.521
2000 Ceccarelli DFJ, Frappier L. Functional analyses of the EBNA1 origin DNA binding protein of Epstein- Barr virus Journal of Virology. 74: 4939-4948. PMID 10799567 DOI: 10.1128/Jvi.74.11.4939-4948.2000  0.552
1999 Bochkarev A, Bochkareva E, Frappier L, Edwards AM. The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding Embo Journal. 18: 4498-4504. PMID 10449415 DOI: 10.1093/Emboj/18.16.4498  0.475
1999 Shire K, Ceccarelli DFJ, Avolio-Hunter TM, Frappier L. EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance Journal of Virology. 73: 2587-2595. PMID 10074103 DOI: 10.1128/Jvi.73.4.2587-2595.1999  0.591
1998 Bochkarev A, Bochkareva E, Frappier L, Edwards AM. The 2.2 Å structure of a permanganate-sensitive DNA site bound by the Epstein-Barr virus origin binding protein, EBNA1 Journal of Molecular Biology. 284: 1273-1278. PMID 9878348 DOI: 10.1006/Jmbi.1998.2247  0.456
1998 Avolio-Hunter TM, Frappier L. Mechanistic studies on the DNA linking activity of Epstein-Barr nuclear antigen 1 Nucleic Acids Research. 26: 4462-4470. PMID 9742250 DOI: 10.1093/Nar/26.19.4462  0.507
1998 Edwards AM, Bochkarev A, Frappier L. Origin DNA-binding proteins Current Opinion in Structural Biology. 8: 49-53. PMID 9519296 DOI: 10.1016/S0959-440X(98)80009-2  0.496
1998 Bochkareva E, Frappier L, Edwards AM, Bochkarev A. The RPA32 subunit of human replication protein A contains a single- stranded DNA-binding domain Journal of Biological Chemistry. 273: 3932-3936. PMID 9461578 DOI: 10.1074/Jbc.273.7.3932  0.471
1998 Zhang D, Frappier L, Gibbs E, Hurwitz J, O'Donnell M. Human RPA (hSSB) interacts with EBNA1, the latent origin binding protein of Epstein-Barr virus. Nucleic Acids Research. 26: 631-7. PMID 9421526 DOI: 10.1093/Nar/26.2.631  0.554
1997 Blake N, Lee S, Redchenko I, Thomas W, Steven N, Leese A, Steigerwald-Mullen P, Kurilla MG, Frappier L, Rickinson A. Human CD8+ T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing Immunity. 7: 791-802. PMID 9430224 DOI: 10.1016/S1074-7613(00)80397-0  0.403
1997 Summers H, Fleming A, Frappier L. Requirements for Epstein-Barr nuclear antigen 1 (EBNA1)-induced permanganate sensitivity of the Epstein-Barr virus latent origin of DNA replication Journal of Biological Chemistry. 272: 26434-26440. PMID 9334219 DOI: 10.1074/Jbc.272.42.26434  0.487
1997 Pfuetzner RA, Bochkarev A, Frappier L, Edwards AM. Replication protein A: Characterization and crystallization of the DNA binding domain Journal of Biological Chemistry. 272: 430-434. PMID 8995279 DOI: 10.1074/Jbc.272.1.430  0.446
1997 Bochkarev A, Pfuetzner RA, Edwards AM, Frappier L. Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA Nature. 385: 176-181. PMID 8990123 DOI: 10.1038/385176A0  0.491
1996 Ermakova OV, Frappier L, Schildkraut CL. Role of the EBNA-1 protein in pausing of replication forks in the Epstein-Barr virus genome Journal of Biological Chemistry. 271: 33009-33017. PMID 8955146 DOI: 10.1074/Jbc.271.51.33009  0.579
1996 Bochkarev A, Barawell JA, Pfuetzner RA, Bochkareva E, Frappier L, Edwards AM. Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein, EBNA1, bound to DNA Cell. 84: 791-800. PMID 8625416 DOI: 10.1016/S0092-8674(00)81056-9  0.518
1996 Summers H, Barwell JA, Pfuetzner RA, Edwards AM, Frappier L. Cooperative assembly of EBNA1 on the Epstein-Barr virus latent origin of replication Journal of Virology. 70: 1228-1231. PMID 8551585 DOI: 10.1128/Jvi.70.2.1228-1231.1996  0.553
1995 Laine A, Frappier L. Identification of Epstein-Barr virus nuclear antigen 1 protein domains that direct interactions at a distance between DNA-bound proteins Journal of Biological Chemistry. 270: 30914-30918. PMID 8537346 DOI: 10.1074/Jbc.270.52.30914  0.552
1995 Barwell JA, Bochkarev A, Pfuetzner RA, Tong H, Yang DSC, Frappier L, Edwards AM. Overexpression, purification, and crystallization of the DNA binding and dimerization domains of the Epstein-Barr virus nuclear antigen Journal of Biological Chemistry. 270: 20556-20559. PMID 7657632 DOI: 10.1074/Jbc.270.35.20556  0.353
1995 Bochkarev A, Barwell JA, Pfuetzner RA, Furey W, Edwards AM, Frappier L. Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA1 Cell. 83: 39-46. PMID 7553871 DOI: 10.1016/0092-8674(95)90232-5  0.498
1994 Frappier L, Goldsmith K, Bendell L. Stabilization of the EBNA1 protein on the Epstein-Barr virus latent origin of DNA replication by a DNA looping mechanism Journal of Biological Chemistry. 269: 1057-1062. PMID 8288561  0.428
1993 Goldsmith K, Bendell L, Frappier L. Identification of EBNA1 amino acid sequences required for the interaction of the functional elements of the Epstein-Barr virus latent origin of DNA replication Journal of Virology. 67: 3418-3426. PMID 8388506 DOI: 10.1128/Jvi.67.6.3418-3426.1993  0.476
1992 Frappier L, O'Donnell M. EBNA1 distorts oriP, the Epstein-Barr virus latent replication origin Journal of Virology. 66: 1786-1790. PMID 1310782 DOI: 10.1128/Jvi.66.3.1786-1790.1992  0.458
1991 Frappier L, O'Donnell M. Overproduction, purification, and characterization of EBNA1, the origin binding protein of Epstein-Barr virus Journal of Biological Chemistry. 266: 7819-7826. PMID 1850421  0.388
1991 Frappier L, O'Donnell M. Epstein-Barr nuclear antigen 1 mediates a DNA loop within the latent replication origin of Epstein-Barr virus Proceedings of the National Academy of Sciences of the United States of America. 88: 10875-10879. PMID 1660154 DOI: 10.1073/Pnas.88.23.10875  0.443
1991 Pearson CE, Frappier L, Zannis-Hadjopoulos M. Plasmids bearing mammalian DNA-replication origin-enriched (ors) fragments initiate semiconservative replication in a cell-free system Bba - Gene Structure and Expression. 1090: 156-166. PMID 1657184 DOI: 10.1016/0167-4781(91)90096-5  0.317
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