Timothy W. Behrens - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology, Microbiology Biology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Owczarczyk K, Cascino MD, Holweg C, Tew GW, Ortmann W, Behrens TW, Schindler T, Langford CA, St Clair EW, Merkel PA, Spiera R, Seo P, Kallenberg CG, Specks U, Lim N, et al. Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis. Jci Insight. PMID 32841219 DOI: 10.1172/Jci.Insight.136180  0.352
2019 Simpfendorfer KR, Li W, Shih A, Wen H, Kothari HP, Einsidler EA, Wuster A, Hunkapiller J, Behrens TW, Graham RR, Townsend MJ, Behar DM, Hu R, Greenspan E, Gregersen PK. Influence of genetic copy number variants of the human GLUT3 glucose transporter gene on protein expression, glycolysis and rheumatoid arthritis risk: A genetic replication study. Molecular Genetics and Metabolism Reports. 19: 100470. PMID 30997344 DOI: 10.1016/J.Ymgmr.2019.100470  0.336
2018 Skon-Hegg C, Zhang J, Wu X, Sagolla M, Ota N, Wuster A, Tom J, Doran E, Ramamoorthi N, Caplazi P, Monroe J, Lee WP, Behrens TW. LACC1 Regulates TNF and IL-17 in Mouse Models of Arthritis and Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 30510070 DOI: 10.4049/Jimmunol.1800636  0.323
2018 Ye CJ, Chen J, Villani AC, Gate RE, Subramaniam M, Bhangale T, Lee MN, Raj T, Raychowdhury R, Li W, Rogel N, Simmons S, Imboywa SH, Chipendo PI, McCabe C, ... ... Behrens T, et al. Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of transcripts under balancing selection. Genome Research. PMID 30446528 DOI: 10.1101/Gr.240390.118  0.381
2018 Rathore N, Ramani SR, Pantua H, Payandeh J, Bhangale T, Wuster A, Kapoor M, Sun Y, Kapadia SB, Gonzalez L, Zarrin AA, Goate A, Hansen DV, Behrens TW, Graham RR. Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease. Plos Genetics. 14: e1007427. PMID 30388101 DOI: 10.1371/Journal.Pgen.1007427  0.371
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Behrens TW, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.346
2017 Langefeld CD, Ainsworth HC, Graham DSC, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, ... ... Behrens TW, et al. Transancestral mapping and genetic load in systemic lupus erythematosus. Nature Communications. 8: 16021. PMID 28714469 DOI: 10.1038/Ncomms16021  0.371
2017 Sitrin J, Suto E, Wuster A, Eastham-Anderson J, Kim JM, Austin CD, Lee WP, Behrens TW. The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 28696253 DOI: 10.4049/Jimmunol.1700608  0.41
2016 Wuster A, Chang D, Behrens TW, Bhangale TR. geneAttribution: trait agnostic identification of candidate genes associated with noncoding variation. Bioinformatics (Oxford, England). PMID 28035029 DOI: 10.1093/Bioinformatics/Btw698  0.326
2016 Bronson PG, Chang D, Bhangale T, Seldin MF, Ortmann W, Ferreira RC, Urcelay E, Pereira LF, Martin J, Plebani A, Lougaris V, Friman V, Freiberger T, Litzman J, Thon V, ... ... Behrens TW, et al. Common variants at PVT1, ATG13-AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency. Nature Genetics. PMID 27723758 DOI: 10.1038/Ng.3675  0.338
2016 Wuster A, Behrens TW. Thinking differently about lupus. Elife. 5. PMID 27023642 DOI: 10.7554/Elife.15352  0.326
2015 Bentham J, Morris DL, Cunninghame Graham DS, Pinder CL, Tombleson P, Behrens TW, Martín J, Fairfax BP, Knight JC, Chen L, Replogle J, Syvänen AC, Rönnblom L, Graham RR, Wither JE, et al. Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Nature Genetics. PMID 26502338 DOI: 10.1038/Ng.3434  0.415
2015 Hung T, Pratt G, Sundararaman B, Townsend MJ, Chaivorapol C, Bhangale T, Graham RR, Ortmann W, Criswell LA, Yeo G, Behrens TW. The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression. Science (New York, N.Y.). PMID 26382853 DOI: 10.1126/Science.Aac7442  0.303
2015 Kennedy WP, Maciuca R, Wolslegel K, Tew W, Abbas AR, Chaivorapol C, Morimoto A, McBride JM, Brunetta P, Richardson BC, Davis JC, Behrens TW, Townsend MJ. Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE. Lupus Science & Medicine. 2: e000080. PMID 25861459 DOI: 10.1136/Lupus-2014-000080  0.334
2015 Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, ... ... Behrens T, et al. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. Plos One. 10: e0122271. PMID 25849893 DOI: 10.1371/Journal.Pone.0122271  0.346
2015 Morris DL, Taylor KE, Fernando MMA, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, et al. Erratum: Unraveling Multiple MHC Gene Associations with Systemic Lupus Erythematosus: Model Choice Indicates a Role for HLA Alleles and Non-HLA Genes in Europeans (The American Journal of Human Genetics (2012) 91 (778-793)) American Journal of Human Genetics. 97. DOI: 10.1016/J.Ajhg.2015.08.005  0.358
2014 Wetzel-Smith MK, Hunkapiller J, Bhangale TR, Srinivasan K, Maloney JA, Atwal JK, Sa SM, Yaylaoglu MB, Foreman O, Ortmann W, Rathore N, Hansen DV, Tessier-Lavigne M, Mayeux R, ... ... Behrens TW, et al. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nature Medicine. 20: 1452-7. PMID 25419706 DOI: 10.1038/Nm.3736  0.329
2014 Chung SA, Brown EE, Williams AH, Ramos PS, Berthier CC, Bhangale T, Alarcon-Riquelme ME, Behrens TW, Criswell LA, Graham DC, Demirci FY, Edberg JC, Gaffney PM, Harley JB, Jacob CO, et al. Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. Journal of the American Society of Nephrology : Jasn. 25: 2859-70. PMID 24925725 DOI: 10.1681/Asn.2013050446  0.347
2014 Guthridge JM, Lu R, Sun H, Sun C, Wiley GB, Dominguez N, Macwana SR, Lessard CJ, Kim-Howard X, Cobb BL, Kaufman KM, Kelly JA, Langefeld CD, Adler AJ, Harley IT, ... ... Behrens TW, et al. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. American Journal of Human Genetics. 94: 586-98. PMID 24702955 DOI: 10.1016/J.Ajhg.2014.03.008  0.405
2014 Morris DL, Fernando MM, Taylor KE, Chung SA, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, et al. MHC associations with clinical and autoantibody manifestations in European SLE. Genes and Immunity. 15: 210-7. PMID 24598797 DOI: 10.1038/Gene.2014.6  0.362
2014 Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, ... ... Behrens T, et al. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiology of Aging. 35: 1510.e19-26. PMID 24439484 DOI: 10.1016/J.Neurobiolaging.2013.12.010  0.331
2014 Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, ... ... Behrens TW, et al. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 506: 376-81. PMID 24390342 DOI: 10.1038/Nature12873  0.503
2014 Owczarczyk K, Holweg C, Ortmann W, Behrens T, Brunetta P, Specks U, Phippard D, Ding L, Lim N, Tchao N, Ikle D, Stone J. OP0232 The Role of Baseline FCRL5 MRNA Expression in Predicting Response to Rituximab (RTX) Therapy in Patients with Granulomatous Polyangiitis (GPA) or Microscopic Polyangiitis (MPA) Annals of the Rheumatic Diseases. 73: 150.1-150. DOI: 10.1136/Annrheumdis-2014-Eular.4265  0.304
2013 Wang C, Ahlford A, Järvinen TM, Nordmark G, Eloranta ML, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Sjöwall C, ... ... Behrens TW, et al. Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations. European Journal of Human Genetics : Ejhg. 21: 994-9. PMID 23249952 DOI: 10.1038/Ejhg.2012.277  0.337
2012 Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, et al. Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. American Journal of Human Genetics. 91: 778-93. PMID 23084292 DOI: 10.1016/J.Ajhg.2012.08.026  0.337
2012 Manjarrez-Orduño N, Marasco E, Chung SA, Katz MS, Kiridly JF, Simpfendorfer KR, Freudenberg J, Ballard DH, Nashi E, Hopkins TJ, Cunninghame Graham DS, Lee AT, Coenen MJ, Franke B, Swinkels DW, ... ... Behrens TW, et al. CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation. Nature Genetics. 44: 1227-30. PMID 23042117 DOI: 10.1038/Ng.2439  0.453
2012 Richman IB, Taylor KE, Chung SA, Trupin L, Petri M, Yelin E, Graham RR, Lee A, Behrens TW, Gregersen PK, Seldin MF, Criswell LA. European genetic ancestry is associated with a decreased risk of lupus nephritis. Arthritis and Rheumatism. 64: 3374-82. PMID 23023776 DOI: 10.1002/Art.34567  0.326
2012 Bronson PG, Chaivorapol C, Ortmann W, Behrens TW, Graham RR. The genetics of type I interferon in systemic lupus erythematosus. Current Opinion in Immunology. 24: 530-7. PMID 22889593 DOI: 10.1016/J.Coi.2012.07.008  0.349
2012 Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, ... ... Behrens TW, et al. Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Ophthalmology. 119: 1874-85. PMID 22705344 DOI: 10.1016/J.Ophtha.2012.03.014  0.309
2012 Ferreira RC, Pan-Hammarström Q, Graham RR, Fontán G, Lee AT, Ortmann W, Wang N, Urcelay E, Fernández-Arquero M, Núñez C, Jorgensen G, Ludviksson BR, Koskinen S, Haimila K, Padyukov L, ... ... Behrens TW, et al. High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency. Plos Genetics. 8: e1002476. PMID 22291608 DOI: 10.1371/Journal.Pgen.1002476  0.373
2011 Cunninghame Graham DS, Morris DL, Bhangale TR, Criswell LA, Syvänen AC, Rönnblom L, Behrens TW, Graham RR, Vyse TJ. Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus. Plos Genetics. 7: e1002341. PMID 22046141 DOI: 10.1371/Journal.Pgen.1002341  0.371
2011 Pidasheva S, Trifari S, Phillips A, Hackney JA, Ma Y, Smith A, Sohn SJ, Spits H, Little RD, Behrens TW, Honigberg L, Ghilardi N, Clark HF. Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q. Plos One. 6: e25038. PMID 22022372 DOI: 10.1371/Journal.Pone.0025038  0.355
2011 Owczarczyk K, Lal P, Abbas AR, Wolslegel K, Holweg CT, Dummer W, Kelman A, Brunetta P, Lewin-Koh N, Sorani M, Leong D, Fielder P, Yocum D, Ho C, Ortmann W, ... ... Behrens TW, et al. A plasmablast biomarker for nonresponse to antibody therapy to CD20 in rheumatoid arthritis. Science Translational Medicine. 3: 101ra92. PMID 21937757 DOI: 10.1126/Scitranslmed.3002432  0.34
2011 Behrens TW. Lyp breakdown and autoimmunity. Nature Genetics. 43: 821-2. PMID 21874033 DOI: 10.1038/Ng.914  0.356
2011 Cotsapas C, Voight BF, Rossin E, Lage K, Neale BM, Wallace C, Abecasis GR, Barrett JC, Behrens T, Cho J, De Jager PL, Elder JT, Graham RR, Gregersen P, Klareskog L, et al. Pervasive sharing of genetic effects in autoimmune disease. Plos Genetics. 7: e1002254. PMID 21852963 DOI: 10.1371/Journal.Pgen.1002254  0.355
2011 Wang N, Shen N, Vyse TJ, Anand V, Gunnarson I, Sturfelt G, Rantapää-Dahlqvist S, Elvin K, Truedsson L, Andersson BA, Dahle C, Ortqvist E, Gregersen PK, Behrens TW, Hammarström L. Selective IgA deficiency in autoimmune diseases. Molecular Medicine (Cambridge, Mass.). 17: 1383-96. PMID 21826374 DOI: 10.2119/Molmed.2011.00195  0.357
2011 Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, ... ... Behrens TW, et al. Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Human Molecular Genetics. 20: 3699-709. PMID 21665990 DOI: 10.1093/Hmg/Ddr270  0.309
2011 Bronson PG, Goldstein BA, Ramsay PP, Beckman KB, Noble JA, Lane JA, Seldin MF, Kelly JA, Harley JB, Moser KL, Gaffney PM, Behrens TW, Criswell LA, Barcellos LF. The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus. Genes and Immunity. 12: 667-71. PMID 21614020 DOI: 10.1038/Gene.2011.36  0.339
2011 Morimoto AM, Flesher DT, Yang J, Wolslegel K, Wang X, Brady A, Abbas AR, Quarmby V, Wakshull E, Richardson B, Townsend MJ, Behrens TW. Association of endogenous anti-interferon-α autoantibodies with decreased interferon-pathway and disease activity in patients with systemic lupus erythematosus. Arthritis and Rheumatism. 63: 2407-15. PMID 21506093 DOI: 10.1002/Art.30399  0.339
2011 Chung SA, Taylor KE, Graham RR, Nititham J, Lee AT, Ortmann WA, Jacob CO, Alarcón-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL, Petri M, Demirci FY, ... ... Behrens TW, et al. Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. Plos Genetics. 7: e1001323. PMID 21408207 DOI: 10.1371/Journal.Pgen.1001323  0.363
2011 Fernando MM, de Smith AJ, Coin L, Morris DL, Froguel P, Mangion J, Blakemore AI, Graham RR, Behrens TW, Vyse TJ. Investigation of the HIN200 locus in UK SLE families identifies novel copy number variants. Annals of Human Genetics. 75: 383-97. PMID 21401563 DOI: 10.1111/J.1469-1809.2011.00641.X  0.378
2011 Taylor KE, Chung SA, Graham RR, Ortmann WA, Lee AT, Langefeld CD, Jacob CO, Kamboh MI, Alarcón-Riquelme ME, Tsao BP, Moser KL, Gaffney PM, Harley JB, Petri M, Manzi S, ... ... Behrens TW, et al. Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes. Plos Genetics. 7: e1001311. PMID 21379322 DOI: 10.1371/Journal.Pgen.1001311  0.357
2011 Yu S, Crawford D, Tsuchihashi T, Behrens TW, Srivastava D. The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 384-93. PMID 21246655 DOI: 10.1002/Dvdy.22549  0.631
2011 Wang Y, Li G, Stanco A, Long JE, Crawford D, Potter GB, Pleasure SJ, Behrens T, Rubenstein JL. CXCR4 and CXCR7 have distinct functions in regulating interneuron migration. Neuron. 69: 61-76. PMID 21220099 DOI: 10.1016/J.Neuron.2010.12.005  0.622
2011 Sandling JK, Garnier S, Sigurdsson S, Wang C, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Mälarstig A, ... ... Behrens TW, et al. A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE. European Journal of Human Genetics : Ejhg. 19: 479-84. PMID 21179067 DOI: 10.1038/Ejhg.2010.197  0.378
2011 Clark H, Pidasheva S, Trifari S, Hackney J, Ma Y, Smith A, Sohn S, Spits H, Little R, Behrens T, Honigberg L, Ghilardi N. Human IL23R R381Q Genetic Variant Implicated in Crohn's Disease Pathogenesis is Hypomorphic Resulting in Reduced Function of the Receptor Gastroenterology. 140: S-273. DOI: 10.1016/S0016-5085(11)61094-9  0.321
2010 Kawasaki A, Ito S, Furukawa H, Hayashi T, Goto D, Matsumoto I, Kusaoi M, Ohashi J, Graham RR, Matsuta K, Behrens TW, Tohma S, Takasaki Y, Hashimoto H, Sumida T, et al. Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study. Arthritis Research & Therapy. 12: R174. PMID 20849588 DOI: 10.1186/Ar3134  0.32
2010 Ferreira RC, Pan-Hammarström Q, Graham RR, Gateva V, Fontán G, Lee AT, Ortmann W, Urcelay E, Fernández-Arquero M, Núñez C, Jorgensen G, Ludviksson BR, Koskinen S, Haimila K, Clark HF, ... ... Behrens TW, et al. Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency. Nature Genetics. 42: 777-80. PMID 20694011 DOI: 10.1038/Ng.644  0.349
2010 Surolia I, Pirnie SP, Chellappa V, Taylor KN, Cariappa A, Moya J, Liu H, Bell DW, Driscoll DR, Diederichs S, Haider K, Netravali I, Le S, Elia R, Dow E, ... ... Behrens TW, et al. Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. Nature. 466: 243-7. PMID 20555325 DOI: 10.1038/Nature09115  0.331
2010 Flesher DL, Sun X, Behrens TW, Graham RR, Criswell LA. Recent advances in the genetics of systemic lupus erythematosus. Expert Review of Clinical Immunology. 6: 461-79. PMID 20441431 DOI: 10.1586/Eci.10.8  0.377
2010 Bronson PG, Komorowski LK, Ramsay PP, May SL, Noble J, Lane JA, Thomson G, Claas FH, Seldin MF, Kelly JA, Harley JB, Moser KL, Gaffney PM, Behrens T, Criswell LA, et al. Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus. Arthritis and Rheumatism. 62: 1712-7. PMID 20191587 DOI: 10.1002/Art.27426  0.302
2010 Richman IB, Chung SA, Taylor KE, Kosoy R, Tian C, Ortmann WA, Nititham J, Lee AT, Rutman S, Petri M, Manzi S, Behrens TW, Gregersen PK, Seldin MF, Criswell LA. European population substructure correlates with systemic lupus erythematosus endophenotypes in North Americans of European descent. Genes and Immunity. 11: 515-21. PMID 19847193 DOI: 10.1038/Gene.2009.80  0.303
2009 Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, et al. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. Plos Genetics. 5: e1000696. PMID 19851445 DOI: 10.1371/Journal.Pgen.1000696  0.334
2009 Rioux JD, Goyette P, Vyse TJ, Hammarström L, Fernando MM, Green T, De Jager PL, Foisy S, Wang J, de Bakker PI, Leslie S, McVean G, Padyukov L, Alfredsson L, ... ... Behrens TW, et al. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proceedings of the National Academy of Sciences of the United States of America. 106: 18680-5. PMID 19846760 DOI: 10.1073/Pnas.0909307106  0.383
2009 Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, Ortmann W, Kosoy R, Ferreira RC, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, ... ... Behrens TW, et al. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nature Genetics. 41: 1228-33. PMID 19838195 DOI: 10.1038/Ng.468  0.361
2009 Bauer JW, Petri M, Batliwalla FM, Koeuth T, Wilson J, Slattery C, Panoskaltsis-Mortari A, Gregersen PK, Behrens TW, Baechler EC. Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study. Arthritis and Rheumatism. 60: 3098-107. PMID 19790071 DOI: 10.1002/Art.24803  0.584
2009 Petri M, Singh S, Tesfasyone H, Dedrick R, Fry K, Lal PG, Williams G, Bauer JW, Gregersen PK, Behrens TW, Baechler EC. Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus Lupus. 18: 980-989. PMID 19762399 DOI: 10.1177/0961203309105529  0.577
2009 Chung SA, Tian C, Taylor KE, Lee AT, Ortmann WA, Hom G, Graham RR, Nititham J, Kelly JA, Morrisey J, Wu H, Yin H, Alarcón-Riquelme ME, Tsao BP, Harley JB, ... ... Behrens TW, et al. European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus. Arthritis and Rheumatism. 60: 2448-56. PMID 19644962 DOI: 10.1002/Art.24707  0.317
2009 Morris DL, Graham RR, Erwig LP, Gaffney PM, Moser KL, Behrens TW, Vyse TJ, Graham DSC. Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE Genes and Immunity. 10: 404-413. PMID 19404301 DOI: 10.1038/Gene.2009.17  0.336
2009 Ito I, Kawasaki A, Ito S, Hayashi T, Goto D, Matsumoto I, Tsutsumi A, Hom G, Graham RR, Takasaki Y, Hashimoto H, Ohashi J, Behrens TW, Sumida T, Tsuchiya N. Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population. Arthritis and Rheumatism. 60: 553-8. PMID 19180478 DOI: 10.1002/Art.24246  0.376
2008 Musone SL, Taylor KE, Lu TT, Nititham J, Ferreira RC, Ortmann W, Shifrin N, Petri MA, Kamboh MI, Manzi S, Seldin MF, Gregersen PK, Behrens TW, Ma A, Kwok PY, et al. Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. Nature Genetics. 40: 1062-4. PMID 19165919 DOI: 10.1038/Ng.202  0.326
2008 Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, Burtt NP, Guiducci C, Parkin M, Gates C, Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, et al. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nature Genetics. 40: 1059-61. PMID 19165918 DOI: 10.1038/Ng.200  0.36
2008 Kawasaki A, Ito I, Hikami K, Ohashi J, Hayashi T, Goto D, Matsumoto I, Ito S, Tsutsumi A, Koga M, Arinami T, Graham RR, Hom G, Takasaki Y, Hashimoto H, ... Behrens TW, et al. Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region. Arthritis Research & Therapy. 10: R113. PMID 18803832 DOI: 10.1186/Ar2516  0.377
2008 Liu C, Batliwalla F, Li W, Lee A, Roubenoff R, Beckman E, Khalili H, Damle A, Kern M, Furie R, Dupuis J, Plenge RM, Coenen MJ, Behrens TW, Carulli JP, et al. Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Molecular Medicine (Cambridge, Mass.). 14: 575-81. PMID 18615156 DOI: 10.2119/2008-00056.Liu  0.357
2008 Tomayko MM, Anderson SM, Brayton CE, Sadanand S, Steinel NC, Behrens TW, Shlomchik MJ. Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities. Journal of Immunology (Baltimore, Md. : 1950). 181: 27-38. PMID 18566367 DOI: 10.4049/Jimmunol.181.1.27  0.395
2008 Taylor KE, Remmers EF, Lee AT, Ortmann WA, Plenge RM, Tian C, Chung SA, Nititham J, Hom G, Kao AH, Demirci FY, Kamboh MI, Petri M, Manzi S, Kastner DL, ... ... Behrens TW, et al. Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus. Plos Genetics. 4: e1000084. PMID 18516230 DOI: 10.1371/Journal.Pgen.1000084  0.38
2008 Kin NW, Crawford DM, Liu J, Behrens TW, Kearney JF. DNA microarray gene expression profile of marginal zone versus follicular B cells and idiotype positive marginal zone B cells before and after immunization with Streptococcus pneumoniae. Journal of Immunology (Baltimore, Md. : 1950). 180: 6663-74. PMID 18453586 DOI: 10.4049/Jimmunol.180.10.6663  0.746
2008 Schram BR, Tze LE, Ramsey LB, Liu J, Najera L, Vegoe AL, Hardy RR, Hippen KL, Farrar MA, Behrens TW. B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements. Journal of Immunology (Baltimore, Md. : 1950). 180: 4728-41. PMID 18354197 DOI: 10.4049/Jimmunol.180.7.4728  0.796
2008 Kawasaki A, Kyogoku C, Ohashi J, Miyashita R, Hikami K, Kusaoi M, Tokunaga K, Takasaki Y, Hashimoto H, Behrens TW, Tsuchiya N. Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: support for a crucial role of intron 1 polymorphisms. Arthritis and Rheumatism. 58: 826-34. PMID 18311811 DOI: 10.1002/Art.23216  0.331
2008 Harley JB, Alarcón-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, Tsao BP, Vyse TJ, Langefeld CD, Nath SK, Guthridge JM, Cobb BL, Mirel DB, Marion MC, ... ... Behrens TW, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nature Genetics. 40: 204-10. PMID 18204446 DOI: 10.1038/Ng.81  0.352
2008 Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, Lee AT, Chung SA, Ferreira RC, Pant PV, Ballinger DG, Kosoy R, Demirci FY, Kamboh MI, Kao AH, ... ... Behrens TW, et al. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. The New England Journal of Medicine. 358: 900-9. PMID 18204098 DOI: 10.1056/Nejmoa0707865  0.373
2008 Cunninghame Graham DS, Graham RR, Manku H, Wong AK, Whittaker JC, Gaffney PM, Moser KL, Rioux JD, Altshuler D, Behrens TW, Vyse TJ. Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nature Genetics. 40: 83-9. PMID 18059267 DOI: 10.1038/Ng.2007.47  0.438
2007 Busconi L, Bauer JW, Tumang JR, Laws A, Perkins-Mesires K, Tabor AS, Lau C, Corley RB, Rothstein TL, Lund FE, Behrens TW, Marshak-Rothstein A. Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9. Journal of Immunology (Baltimore, Md. : 1950). 179: 7397-405. PMID 18025183 DOI: 10.4049/Jimmunol.179.11.7397  0.639
2007 Zheng B, Marinova E, Switzer K, Wansley D, He H, Bheekha-Escura R, Behrens TW, Han S. Overexpression of Bcl(XL) in B cells promotes Th1 response and exacerbates collagen-induced arthritis. Journal of Immunology (Baltimore, Md. : 1950). 179: 7087-92. PMID 17982100 DOI: 10.4049/Jimmunol.179.10.7087  0.46
2007 Remmers EF, Plenge RM, Lee AT, Graham RR, Hom G, Behrens TW, de Bakker PI, Le JM, Lee HS, Batliwalla F, Li W, Masters SL, Booty MG, Carulli JP, Padyukov L, et al. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. The New England Journal of Medicine. 357: 977-86. PMID 17804842 DOI: 10.1056/Nejmoa073003  0.319
2007 Baechler EC, Bauer JW, Slattery CA, Ortmann WA, Espe KJ, Novitzke J, Ytterberg SR, Gregersen PK, Behrens TW, Reed AM. An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. Molecular Medicine (Cambridge, Mass.). 13: 59-68. PMID 17515957 DOI: 10.2119/2006-00085.Baechler  0.586
2007 Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, ... ... Behrens TW, et al. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proceedings of the National Academy of Sciences of the United States of America. 104: 6758-63. PMID 17412832 DOI: 10.1073/Pnas.0701266104  0.609
2007 Sekine H, Ferreira RC, Pan-Hammarström Q, Graham RR, Ziemba B, de Vries SS, Liu J, Hippen K, Koeuth T, Ortmann W, Iwahori A, Elliott MK, Offer S, Skon C, Du L, ... ... Behrens TW, et al. Role for Msh5 in the regulation of Ig class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 104: 7193-8. PMID 17409188 DOI: 10.1073/Pnas.0700815104  0.557
2007 Graham RR, Ortmann W, Rodine P, Espe K, Langefeld C, Lange E, Williams A, Beck S, Kyogoku C, Moser K, Gaffney P, Gregersen PK, Criswell LA, Harley JB, Behrens TW. Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE. European Journal of Human Genetics : Ejhg. 15: 823-30. PMID 17406641 DOI: 10.1038/Sj.Ejhg.5201827  0.341
2007 Manku H, Graham DC, Graham RR, Behrens TW, Behrens TW, Althshuler D, Vyse TJ. The Molecular Basis by Which Polymorphism in the OX40L Gene Predisposes to SLE Clinical Immunology. 123: S134. DOI: 10.1016/J.Clim.2007.03.020  0.303
2006 Bauer JW, Baechler EC, Petri M, Batliwalla FM, Crawford D, Ortmann WA, Espe KJ, Li W, Patel DD, Gregersen PK, Behrens TW. Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus. Plos Medicine. 3: e491. PMID 17177599 DOI: 10.1371/Journal.Pmed.0030491  0.727
2006 Gregersen PK, Behrens TW. Genetics of autoimmune diseases--disorders of immune homeostasis. Nature Reviews. Genetics. 7: 917-28. PMID 17139323 DOI: 10.1038/Nrg1944  0.315
2006 Stoeckman AK, Baechler EC, Ortmann WA, Behrens TW, Michet CJ, Peterson EJ. A distinct inflammatory gene expression profile in patients with psoriatic arthritis. Genes and Immunity. 7: 583-91. PMID 16971957 DOI: 10.1038/Sj.Gene.6364334  0.37
2006 Forabosco P, Gorman JD, Cleveland C, Kelly JA, Fisher SA, Ortmann WA, Johansson C, Johanneson B, Moser KL, Gaffney PM, Tsao BP, Cantor RM, Alarcón-Riquelme ME, Behrens TW, Harley JB, et al. Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus. Genes and Immunity. 7: 609-14. PMID 16971955 DOI: 10.1038/Sj.Gene.6364338  0.307
2006 Ramos PS, Kelly JA, Gray-McGuire C, Bruner GR, Leiran AN, Meyer CM, Namjou B, Espe KJ, Ortmann WA, Reichlin M, Langefeld CD, James JA, Gaffney PM, Behrens TW, Harley JB, et al. Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus. Genes and Immunity. 7: 417-32. PMID 16775618 DOI: 10.1038/Sj.Gene.6364316  0.313
2006 De Jager PL, Graham R, Farwell L, Sawcer S, Richardson A, Behrens TW, Compston A, Hafler DA, Kere J, Vyse TJ, Rioux JD. The role of inflammatory bowel disease susceptibility loci in multiple sclerosis and systemic lupus erythematosus. Genes and Immunity. 7: 327-34. PMID 16642031 DOI: 10.1038/Sj.Gene.6364303  0.338
2006 Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, Ortmann WA, Koeuth T, González Escribano MF, Pons-Estel B, Petri M, Daly M, Gregersen PK, Martín J, ... ... Behrens TW, et al. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nature Genetics. 38: 550-5. PMID 16642019 DOI: 10.1038/Ng1782  0.627
2006 Baechler EC, Batliwalla FM, Reed AM, Peterson EJ, Gaffney PM, Moser KL, Gregersen PK, Behrens TW. Gene expression profiling in human autoimmunity. Immunological Reviews. 210: 120-37. PMID 16623768 DOI: 10.1111/J.0105-2896.2006.00367.X  0.357
2006 Hastings WD, Tumang JR, Behrens TW, Rothstein TL. Peritoneal B-2 cells comprise a distinct B-2 cell population with B-1b-like characteristics. European Journal of Immunology. 36: 1114-23. PMID 16609926 DOI: 10.1002/Eji.200535142  0.439
2006 Liu J, Karypis G, Hippen KL, Vegoe AL, Ruiz P, Gilkeson GS, Behrens TW. Genomic view of systemic autoimmunity in MRLlpr mice. Genes and Immunity. 7: 156-68. PMID 16508641 DOI: 10.1038/Sj.Gene.6364286  0.545
2005 Batliwalla FM, Li W, Ritchlin CT, Xiao X, Brenner M, Laragione T, Shao T, Durham R, Kemshetti S, Schwarz E, Coe R, Kern M, Baechler EC, Behrens TW, Gregersen PK, et al. Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis. Molecular Medicine (Cambridge, Mass.). 11: 21-9. PMID 16622521 DOI: 10.2119/2006-00003.Gulko  0.341
2005 Hippen KL, Schram BR, Tze LE, Pape KA, Jenkins MK, Behrens TW. In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance. Journal of Immunology (Baltimore, Md. : 1950). 175: 909-16. PMID 16002689 DOI: 10.4049/Jimmunol.175.2.909  0.781
2005 Behrens TW, Graham RR, Kyogoku C, Baechler EC, Ramos PS, Gillett C, Bauer J, Ortmann WA, Hippen KL, Peterson E, Langefeld CD, Moser KL, Gaffney PM, Gregersen PK. Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus. Novartis Foundation Symposium. 267: 145-60; discussion 1. PMID 15999805 DOI: 10.1002/047002139X.Ch10  0.602
2005 Batliwalla FM, Baechler EC, Xiao X, Li W, Balasubramanian S, Khalili H, Damle A, Ortmann WA, Perrone A, Kantor AB, Gulko PS, Kern M, Furie R, Behrens TW, Gregersen PK. Peripheral blood gene expression profiling in rheumatoid arthritis Genes and Immunity. 6: 388-397. PMID 15973463 DOI: 10.1038/Sj.Gene.6364209  0.344
2005 Tze LE, Schram BR, Lam KP, Hogquist KA, Hippen KL, Liu J, Shinton SA, Otipoby KL, Rodine PR, Vegoe AL, Kraus M, Hardy RR, Schlissel MS, Rajewsky K, Behrens TW. Basal immunoglobulin signaling actively maintains developmental stage in immature B cells. Plos Biology. 3: e82. PMID 15752064 DOI: 10.1371/Journal.Pbio.0030082  0.794
2005 Criswell LA, Pfeiffer KA, Lum RF, Gonzales B, Novitzke J, Kern M, Moser KL, Begovich AB, Carlton VE, Li W, Lee AT, Ortmann W, Behrens TW, Gregersen PK. Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes. American Journal of Human Genetics. 76: 561-71. PMID 15719322 DOI: 10.1086/429096  0.359
2004 Baechler EC, Gregersen PK, Behrens TW. The emerging role of interferon in human systemic lupus erythematosus. Current Opinion in Immunology. 16: 801-7. PMID 15511676 DOI: 10.1016/J.Coi.2004.09.014  0.372
2004 Kyogoku C, Langefeld CD, Ortmann WA, Lee A, Selby S, Carlton VE, Chang M, Ramos P, Baechler EC, Batliwalla FM, Novitzke J, Williams AH, Gillett C, Rodine P, Graham RR, ... ... Behrens TW, et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. American Journal of Human Genetics. 75: 504-7. PMID 15273934 DOI: 10.1086/423790  0.34
2004 Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Moser K, Ortmann WA, Espe KJ, Balasubramanian S, Hughes KM, Chan JP, Begovich A, Chang SYP, Gregersen PK, Behrens TW. Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation Genes and Immunity. 5: 347-353. PMID 15175644 DOI: 10.1038/Sj.Gene.6364098  0.301
2004 Swanson PJ, Kuslak SL, Fang W, Tze L, Gaffney P, Selby S, Hippen KL, Nunez G, Sidman CL, Behrens TW. Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc. Journal of Immunology (Baltimore, Md. : 1950). 172: 6684-91. PMID 15153484 DOI: 10.4049/Jimmunol.172.11.6684  0.779
2003 Tze LE, Hippen KL, Behrens TW. Late immature B cells (IgMhighIgDneg) undergo a light chain receptor editing response to soluble self-antigen. Journal of Immunology (Baltimore, Md. : 1950). 171: 678-82. PMID 12847233 DOI: 10.4049/Jimmunol.171.2.678  0.789
2003 Pape KA, Kouskoff V, Nemazee D, Tang HL, Cyster JG, Tze LE, Hippen KL, Behrens TW, Jenkins MK. Visualization of the genesis and fate of isotype-switched B cells during a primary immune response. The Journal of Experimental Medicine. 197: 1677-87. PMID 12796466 DOI: 10.1084/Jem.20012065  0.779
2003 Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Ortmann WA, Espe KJ, Shark KB, Grande WJ, Hughes KM, Kapur V, Gregersen PK, Behrens TW. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proceedings of the National Academy of Sciences of the United States of America. 100: 2610-5. PMID 12604793 DOI: 10.1073/Pnas.0337679100  0.395
2003 Suzuki H, Matsuda S, Terauchi Y, Fujiwara M, Ohteki T, Asano T, Behrens TW, Kouro T, Takatsu K, Kadowaki T, Koyasu S. PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction. Nature Immunology. 4: 280-6. PMID 12563258 DOI: 10.1038/Ni890  0.427
2002 Jawaheer D, Li W, Graham RR, Chen W, Damle A, Xiao X, Monteiro J, Khalili H, Lee A, Lundsten R, Begovich A, Bugawan T, Erlich H, Elder JT, Criswell LA, ... ... Behrens TW, et al. Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis. American Journal of Human Genetics. 71: 585-94. PMID 12181776 DOI: 10.1086/342407  0.349
2002 Graham RR, Ortmann WA, Langefeld CD, Jawaheer D, Selby SA, Rodine PR, Baechler EC, Rohlf KE, Shark KB, Espe KJ, Green LE, Nair RP, Stuart PE, Elder JT, King RA, ... ... Behrens TW, et al. Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. American Journal of Human Genetics. 71: 543-53. PMID 12145745 DOI: 10.1086/342290  0.325
2002 Gaffney PM, Moser KL, Graham RR, Behrens TW. Recent advances in the genetics of systemic lupus erythematosus. Rheumatic Diseases Clinics of North America. 28: 111-26. PMID 11840693 DOI: 10.1016/S0889-857X(03)00072-3  0.369
2001 Owyang AM, Tumang JR, Schram BR, Hsia CY, Behrens TW, Rothstein TL, Liou HC. c-Rel is required for the protection of B cells from antigen receptor-mediated, but not Fas-mediated, apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 167: 4948-56. PMID 11673501 DOI: 10.4049/Jimmunol.167.9.4948  0.376
2001 Wakeland EK, Liu K, Graham RR, Behrens TW. Delineating the genetic basis of systemic lupus erythematosus Immunity. 15: 397-408. PMID 11567630 DOI: 10.1016/S1074-7613(01)00201-1  0.354
2001 Graham RR, Langefeld CD, Gaffney PM, Ortmann WA, Selby SA, Baechler EC, Shark KB, Ockenden TC, Rohlf KE, Moser KL, Brown WM, Gabriel SE, Messner RP, King RA, Horak P, ... ... Behrens TW, et al. Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus. Arthritis Research. 3: 299-305. PMID 11549371 DOI: 10.1186/Ar319  0.303
2000 Tze LE, Baness EA, Hippen KL, Behrens TW. Ig light chain receptor editing in anergic B cells. Journal of Immunology (Baltimore, Md. : 1950). 165: 6796-802. PMID 11120801 DOI: 10.4049/Jimmunol.165.12.6796  0.786
2000 Gray-Mcguire C, Moser KL, Gaffney PM, Kelly J, Yu H, Olson JM, Jedrey CM, Jacobs KB, Kimberly RP, Neas BR, Rich SS, Behrens TW, Harley JB. Genome scan of human systemic lupus erythematosus by regression modeling: Evidence of linkage and epistasis at 4p16-15.2 American Journal of Human Genetics. 67: 1460-1469. PMID 11078476 DOI: 10.1086/316891  0.305
2000 Hippen KL, Tze LE, Behrens TW. CD5 maintains tolerance in anergic B cells. The Journal of Experimental Medicine. 191: 883-90. PMID 10704468 DOI: 10.1084/Jem.191.5.883  0.782
2000 Gaffney PM, Ortmann WA, Selby SA, Shark KB, Ockenden TC, Rohlf KE, Walgrave NL, Boyum WP, Malmgren ML, Miller ME, Kearns GM, Messner RP, King RA, Rich SS, Behrens TW. Genome screening in human systemic lupus erythematosus: Results from a second Minnesota cohort and combined analyses of 187 sib-pair families American Journal of Human Genetics. 66: 547-556. PMID 10677315 DOI: 10.1086/302767  0.326
1999 Takahashi Y, Cerasoli DM, Dal Porto JM, Shimoda M, Freund R, Fang W, Telander DG, Malvey EN, Mueller DL, Behrens TW, Kelsoe G. Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice. The Journal of Experimental Medicine. 190: 399-410. PMID 10430628 DOI: 10.1084/Jem.190.3.399  0.357
1998 Harley JB, Moser KL, Gaffney PM, Behrens TW. The genetics of human systemic lupus erythematosus Current Opinion in Immunology. 10: 690-696. PMID 9914226 DOI: 10.1016/S0952-7915(98)80090-3  0.369
1998 Gaffney PM, Kearns GM, Shark KB, Ortmann WA, Selby SA, Malmgren ML, Rohlf KE, Ockenden TC, Messner RP, King RA, Rich SS, Behrens TW. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families Proceedings of the National Academy of Sciences of the United States of America. 95: 14875-14879. PMID 9843983 DOI: 10.1073/Pnas.95.25.14875  0.332
1998 Fang W, Weintraub BC, Dunlap B, Garside P, Pape KA, Jenkins MK, Goodnow CC, Mueller DL, Behrens TW. Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing. Immunity. 9: 35-45. PMID 9697834 DOI: 10.1016/S1074-7613(00)80586-5  0.455
1998 Solvason N, Wu WW, Kabra N, Lund-Johansen F, Roncarolo MG, Behrens TW, Grillot DA, Nunez G, Lees E, Howard M. Transgene expression of bcl-xL permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells. The Journal of Experimental Medicine. 187: 1081-91. PMID 9529324 DOI: 10.1084/Jem.187.7.1081  0.428
1997 Behrens TW, Mueller DL. Bcl-x and the regulation of survival in the immune system Immunologic Research. 16: 149-160. PMID 9212361 DOI: 10.1007/Bf02786359  0.394
1997 Fang W, Nath KA, Mackey MF, Noelle RJ, Mueller DL, Behrens TW. CD40 inhibits B cell apoptosis by upregulating bcl-x(L) expression and blocking oxidant accumulation American Journal of Physiology - Cell Physiology. 272. PMID 9124531 DOI: 10.1152/Ajpcell.1997.272.3.C950  0.354
1996 Fang W, Mueller DL, Pennell CA, Rivard JJ, Li YS, Hardy RR, Schlissel MS, Behrens TW. Frequent aberrant immunoglobulin gene rearrangements in Pro-B cells revealed by a bcl-xl transgene Immunity. 4: 291-299. PMID 8624819 DOI: 10.1016/S1074-7613(00)80437-9  0.45
1996 Fang W, Mueller DL, Pennell CA, Rivard JJ, Li Y, Hardy Mark S Schlissel RR, Behrens TW. Frequent aberrant immunoglobulin gene rearrangements in PRO-B cells revealed by a BCL-XL transgene Faseb Journal. 10.  0.36
1993 Scherle P, Behrens T, Staudt LM. Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 7568-72. PMID 8356058 DOI: 10.1073/Pnas.90.16.7568  0.358
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