| Year |
Citation |
Score |
| 2022 |
Lewin AS, Smith WC. Gene Therapy for Rhodopsin Mutations. Cold Spring Harbor Perspectives in Medicine. PMID 35940643 DOI: 10.1101/cshperspect.a041283 |
0.309 |
|
| 2019 |
Brown EE, Lewin AS, Ash JD. AMPK May Play an Important Role in the Retinal Metabolic Ecosystem. Advances in Experimental Medicine and Biology. 1185: 477-481. PMID 31884657 DOI: 10.1007/978-3-030-27378-1_78 |
0.357 |
|
| 2019 |
Ahmed CM, Dwyer BT, Romashko A, Van Adestine S, Park EH, Lou Z, Welty D, Josiah S, Savinainen A, Zhang B, Lewin AS. SRD005825 Acts as a Pharmacologic Chaperone of Opsin and Promotes Survival of Photoreceptors in an Animal Model of Autosomal Dominant Retinitis Pigmentosa. Translational Vision Science & Technology. 8: 30. PMID 31857914 DOI: 10.1167/Tvst.8.6.30 |
0.366 |
|
| 2019 |
Ridley RB, Young BM, Lee J, Walsh E, Ahmed CM, Lewin AS, Ildefonso CJ. AAV Mediated Delivery of Myxoma Virus M013 Gene Protects the Retina against Autoimmune Uveitis. Journal of Clinical Medicine. 8. PMID 31795515 DOI: 10.3390/Jcm8122082 |
0.418 |
|
| 2019 |
Young BM, Jones K, Massengill MT, Walsh E, Li H, Lewin AS, Ildefonso CJ. Expression of a CARD Slows the Retinal Degeneration of a Geographic Atrophy Mouse Model. Molecular Therapy. Methods & Clinical Development. 14: 113-125. PMID 31334304 DOI: 10.1016/J.Omtm.2019.06.001 |
0.385 |
|
| 2019 |
Brown EE, DeWeerd AJ, Ildefonso CJ, Lewin AS, Ash JD. Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors. Redox Biology. 24: 101201. PMID 31039480 DOI: 10.1016/J.Redox.2019.101201 |
0.41 |
|
| 2019 |
Massengill MT, Young BM, Lewin AS, Ildefonso CJ. Co-Delivery of a Short-Hairpin RNA and a shRNA-Resistant Replacement Gene with Adeno-Associated Virus: An Allele-Independent Strategy for Autosomal-Dominant Retinal Disorders. Methods in Molecular Biology (Clifton, N.J.). 1937: 235-258. PMID 30706401 DOI: 10.1007/978-1-4939-9065-8_15 |
0.428 |
|
| 2018 |
Massengill MT, Young B, Patel D, Jafri F, Sabogal E, Ash N, Li H, Ildefonso CJ, Lewin AS. Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa. Investigative Ophthalmology & Visual Science. 59: 5417-5430. PMID 30452595 DOI: 10.1167/Iovs.18-25345 |
0.329 |
|
| 2018 |
Biswal MR, Justis BD, Han P, Li H, Gierhart D, Dorey CK, Lewin AS. Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress. Plos One. 13: e0203816. PMID 30265681 DOI: 10.1371/Journal.Pone.0203816 |
0.391 |
|
| 2018 |
Ildefonso CJ, Lewin AS. Adeno-Associated Virus Delivery of Viral Serpins for Ocular Diseases: Design and Validation. Methods in Molecular Biology (Clifton, N.J.). 1826: 237-254. PMID 30194605 DOI: 10.1007/978-1-4939-8645-3_16 |
0.351 |
|
| 2018 |
Cideciyan AV, Sudharsan R, Dufour VL, Massengill MT, Iwabe S, Swider M, Lisi B, Sumaroka A, Marinho LF, Appelbaum T, Rossmiller B, Hauswirth WW, Jacobson SG, Lewin AS, Aguirre GD, et al. Mutation-independent rhodopsin gene therapy by knockdown and replacement with a single AAV vector. Proceedings of the National Academy of Sciences of the United States of America. PMID 30127005 DOI: 10.1073/Pnas.1805055115 |
0.436 |
|
| 2018 |
Biswal MR, Prentice HM, Smith GW, Zhu P, Tong Y, Dorey CK, Lewin AS, Blanks JC. Cell-specific gene therapy driven by an optimized hypoxia-regulated vector reduces choroidal neovascularization. Journal of Molecular Medicine (Berlin, Germany). PMID 30105447 DOI: 10.1007/S00109-018-1683-0 |
0.401 |
|
| 2018 |
Watson ZL, Washington SD, Phelan DM, Lewin AS, Tuli SS, Schultz GS, Neumann DM, Bloom DC. Knock-down of the HSV-1 Latency-Associated Transcript Reduces Reactivation from Latency. Journal of Virology. PMID 29875240 DOI: 10.1128/Jvi.00812-18 |
0.379 |
|
| 2018 |
Chang LJ, Lewin AS. Preface: Translational Gene Therapy Coming of Age! Current Gene Therapy. 18: 1. PMID 29769000 DOI: 10.2174/156652321801180503163908 |
0.304 |
|
| 2018 |
Massengill MT, Ahmed CM, Lewin AS, Ildefonso CJ. Neuroinflammation in Retinitis Pigmentosa, Diabetic Retinopathy, and Age-Related Macular Degeneration: A Minireview. Advances in Experimental Medicine and Biology. 1074: 185-191. PMID 29721943 DOI: 10.1007/978-3-319-75402-4_23 |
0.322 |
|
| 2018 |
Brown EE, Lewin AS, Ash JD. Mitochondria: Potential Targets for Protection in Age-Related Macular Degeneration. Advances in Experimental Medicine and Biology. 1074: 11-17. PMID 29721922 DOI: 10.1007/978-3-319-75402-4_2 |
0.379 |
|
| 2018 |
Yu H, Porciatti V, Lewin A, Hauswirth W, Guy J. Longterm Reversal of Severe Visual Loss by Mitochondrial Gene Transfer in a Mouse Model of Leber Hereditary Optic Neuropathy. Scientific Reports. 8: 5587. PMID 29615737 DOI: 10.1038/S41598-018-23836-Y |
0.427 |
|
| 2018 |
Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, Lewin AS, Rohrer B. Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Molecular Therapy. Methods & Clinical Development. 9: 1-11. PMID 29234687 DOI: 10.1016/J.Omtm.2017.11.003 |
0.351 |
|
| 2017 |
Biswal MR, Han P, Zhu P, Wang Z, Li H, Ildefonso CJ, Lewin AS. Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD. Investigative Ophthalmology & Visual Science. 58: 1237-1245. PMID 28241311 DOI: 10.1167/Iovs.16-21272 |
0.345 |
|
| 2017 |
Song C, Mitter SK, Qi X, Beli E, Rao HV, Ding J, Ip CS, Gu H, Akin D, Dunn WA, Bowes Rickman C, Lewin AS, Grant MB, Boulton ME. Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy. Plos One. 12: e0171940. PMID 28222108 DOI: 10.1371/Journal.Pone.0171940 |
0.34 |
|
| 2017 |
Qi X, Pay SL, Yan Y, Thomas J, Lewin AS, Chang LJ, Grant MB, Boulton ME. Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28202390 DOI: 10.1016/J.Ymthe.2017.01.015 |
0.323 |
|
| 2016 |
Watson ZL, Ertel MK, Lewin AS, Tuli SS, Schultz GS, Neumann DM, Bloom DC. Adeno-Associated Virus Vectors Efficiently Transduce Mouse and Rabbit Sensory Neurons Co-Infected with HSV-1 Following Peripheral Inoculation. Journal of Virology. PMID 27334582 DOI: 10.1128/Jvi.01028-16 |
0.304 |
|
| 2016 |
Rex TS, Kasmala L, Bond WS, de Lucas Cerrillo AM, Wynn K, Lewin AS. Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa. Plos One. 11: e0157411. PMID 27299810 DOI: 10.1371/Journal.Pone.0157411 |
0.379 |
|
| 2016 |
Ildefonso CJ, Jaime H, Brown EE, Iwata RL, Ahmed CM, Massengill MT, Biswal MR, Boye SE, Hauswirth WW, Ash JD, Li Q, Lewin AS. Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide. Investigative Ophthalmology & Visual Science. 57: 372-86. PMID 26842755 DOI: 10.1167/Iovs.15-17703 |
0.345 |
|
| 2016 |
Conley SM, Whalen P, Lewin AS, Naash MI. Characterization of Ribozymes Targeting a Congenital Night Blindness Mutation in Rhodopsin Mutation. Advances in Experimental Medicine and Biology. 854: 509-15. PMID 26427453 DOI: 10.1007/978-3-319-17121-0_68 |
0.371 |
|
| 2016 |
Chiang WC, Joseph V, Yasumura D, Matthes MT, Lewin AS, Gorbatyuk MS, Ahern K, LaVail MM, Lin JH. Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin. Advances in Experimental Medicine and Biology. 854: 185-91. PMID 26427410 DOI: 10.1007/978-3-319-17121-0_25 |
0.367 |
|
| 2016 |
Biswal MR, Ildefonso CJ, Mao H, Seo SJ, Wang Z, Li H, Le YZ, Lewin AS. Conditional Induction of Oxidative Stress in RPE: A Mouse Model of Progressive Retinal Degeneration. Advances in Experimental Medicine and Biology. 854: 31-7. PMID 26427390 DOI: 10.1007/978-3-319-17121-0_5 |
0.359 |
|
| 2015 |
Beltran WA, Cideciyan AV, Iwabe S, Swider M, Kosyk MS, McDaid K, Martynyuk I, Ying GS, Shaffer J, Deng WT, Boye SL, Lewin AS, Hauswirth WW, Jacobson SG, Aguirre GD. Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease. Proceedings of the National Academy of Sciences of the United States of America. 112: E5844-53. PMID 26460017 DOI: 10.1073/Pnas.1509914112 |
0.399 |
|
| 2015 |
Yu H, Koilkonda RD, Chou TH, Porciatti V, Mehta A, Hentall ID, Chiodo VA, Boye SL, Hauswirth WW, Lewin AS, Guy J. Consequences of zygote injection and germline transfer of mutant human mitochondrial DNA in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438859 DOI: 10.1073/Pnas.1506129112 |
0.457 |
|
| 2015 |
Biswal MR, Ahmed CM, Ildefonso CJ, Han P, Li H, Jivanji H, Mao H, Lewin AS. Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress. Experimental Eye Research. 140: 94-105. PMID 26315784 DOI: 10.1016/J.Exer.2015.07.022 |
0.363 |
|
| 2015 |
Ildefonso CJ, Jaime H, Biswal MR, Boye SE, Li Q, Hauswirth WW, Lewin AS. Gene therapy with the caspase activation and recruitment domain reduces the ocular inflammatory response. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 875-84. PMID 25698151 DOI: 10.1038/Mt.2015.30 |
0.379 |
|
| 2015 |
Rossmiller BP, Ryals RC, Lewin AS. Gene therapy to rescue retinal degeneration caused by mutations in rhodopsin. Methods in Molecular Biology (Clifton, N.J.). 1271: 391-410. PMID 25697537 DOI: 10.1007/978-1-4939-2330-4_25 |
0.412 |
|
| 2015 |
Ildefonso CJ, Jaime H, Rahman MM, Li Q, Boye SE, Hauswirth WW, Lucas AR, McFadden G, Lewin AS. Gene delivery of a viral anti-inflammatory protein to combat ocular inflammation. Human Gene Therapy. 26: 59-68. PMID 25420215 DOI: 10.1089/Hum.2014.089 |
0.364 |
|
| 2015 |
Beltran WA, Cideciyan AV, Lewin AS, Hauswirth WW, Jacobson SG, Aguirre GD. Gene augmentation for X-linked retinitis pigmentosa caused by mutations in RPGR. Cold Spring Harbor Perspectives in Medicine. 5: a017392. PMID 25301933 DOI: 10.1101/Cshperspect.A017392 |
0.386 |
|
| 2015 |
Ildefonso CJ, Jaime H, Li Q, Rahman MM, McFadden G, Lewin AS. 607. Gene Therapy Delivering Anti-inflammatory Viral Proteins for Ocular Inflammation Molecular Therapy. 23: S241. DOI: 10.1016/S1525-0016(16)34216-2 |
0.351 |
|
| 2015 |
Biswal MR, Ildefonso C, Wang Z, Mao H, Li H, Zhu P, Quinones G, Lewin AS. 393. Effectiveness of Antioxidant Gene Therapy in Delaying Retinal Degeneration Molecular Therapy. 23: S156. DOI: 10.1016/S1525-0016(16)34002-3 |
0.412 |
|
| 2015 |
Donate AL, Soustek M, Rizzo SA, Santostefano K, Gosiker BJ, Lewin AS, Terada N, Cade T, Byrne BJ, Pacak CA. 187. AAV Delivery of Tafazzin for the Correction of Mitochondrial Dysfunction in Barth Syndrome Using IPS Differentiated Cardiomyocytes Molecular Therapy. 23: S75. DOI: 10.1016/S1525-0016(16)33792-3 |
0.426 |
|
| 2014 |
Mitter SK, Song C, Qi X, Mao H, Rao H, Akin D, Lewin A, Grant M, Dunn W, Ding J, Bowes Rickman C, Boulton M. Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. Autophagy. 10: 1989-2005. PMID 25484094 DOI: 10.4161/Auto.36184 |
0.317 |
|
| 2014 |
Koilkonda R, Yu H, Talla V, Porciatti V, Feuer WJ, Hauswirth WW, Chiodo V, Erger KE, Boye SL, Lewin AS, Conlon TJ, Renner L, Neuringer M, Detrisac C, Guy J. LHON gene therapy vector prevents visual loss and optic neuropathy induced by G11778A mutant mitochondrial DNA: biodistribution and toxicology profile. Investigative Ophthalmology & Visual Science. 55: 7739-53. PMID 25342621 DOI: 10.1167/Iovs.14-15388 |
0.361 |
|
| 2014 |
Lewin AS, Rossmiller B, Mao H. Gene augmentation for adRP mutations in RHO. Cold Spring Harbor Perspectives in Medicine. 4: a017400. PMID 25037104 DOI: 10.1101/Cshperspect.A017400 |
0.406 |
|
| 2014 |
Mao H, Seo SJ, Biswal MR, Li H, Conners M, Nandyala A, Jones K, Le YZ, Lewin AS. Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration. Investigative Ophthalmology & Visual Science. 55: 4613-27. PMID 24985474 DOI: 10.1167/Iovs.14-14633 |
0.374 |
|
| 2014 |
Sriram S, Gibson DJ, Robinson P, Pi L, Tuli S, Lewin AS, Schultz G. Assessment of anti-scarring therapies in ex vivo organ cultured rabbit corneas. Experimental Eye Research. 125: 173-82. PMID 24971495 DOI: 10.1016/J.Exer.2014.06.014 |
0.32 |
|
| 2014 |
Rowe-Rendleman CL, Durazo SA, Kompella UB, Rittenhouse KD, Di Polo A, Weiner AL, Grossniklaus HE, Naash MI, Lewin AS, Horsager A, Edelhauser HF. Drug and gene delivery to the back of the eye: from bench to bedside. Investigative Ophthalmology & Visual Science. 55: 2714-30. PMID 24777644 DOI: 10.1167/Iovs.13-13707 |
0.314 |
|
| 2014 |
Koilkonda RD, Yu H, Chou TH, Feuer WJ, Ruggeri M, Porciatti V, Tse D, Hauswirth WW, Chiodo V, Boye SL, Lewin AS, Neuringer M, Renner L, Guy J. Safety and effects of the vector for the Leber hereditary optic neuropathy gene therapy clinical trial. Jama Ophthalmology. 132: 409-20. PMID 24457989 DOI: 10.1001/Jamaophthalmol.2013.7630 |
0.455 |
|
| 2013 |
Wang R, Mason DE, Choe KP, Lewin AS, Peters EC, Luesch H. In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway Acs Chemical Biology. 8: 1764-1774. PMID 23773140 DOI: 10.1021/Cb4000103 |
0.351 |
|
| 2013 |
Talla V, Yu H, Chou TH, Porciatti V, Chiodo V, Boye SL, Hauswirth WW, Lewin AS, Guy J. NADH-dehydrogenase type-2 suppresses irreversible visual loss and neurodegeneration in the EAE animal model of MS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1876-88. PMID 23752309 DOI: 10.1038/Mt.2013.104 |
0.377 |
|
| 2013 |
Nashine S, Bhootada Y, Lewin AS, Gorbatyuk M. Ablation of C/EBP Homologous Protein Does Not Protect T17M RHO Mice from Retinal Degeneration Plos One. 8. PMID 23646198 DOI: 10.1371/Journal.Pone.0063205 |
0.387 |
|
| 2013 |
Boye SE, Boye SL, Lewin AS, Hauswirth WW. A comprehensive review of retinal gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 509-19. PMID 23358189 DOI: 10.1038/Mt.2012.280 |
0.359 |
|
| 2013 |
Sriram S, Gibson D, Robinson P, Tuli S, Lewin AS, Schultz G. Reduction of corneal scarring in rabbits by targeting the TGFB1 pathway with a triple siRNA combination Advances in Bioscience and Biotechnology. 4: 47-55. DOI: 10.4236/Abb.2013.410A4005 |
0.358 |
|
| 2012 |
Rossmiller B, Mao H, Lewin AS. Review: Gene therapy in animal models of autosomal dominant retinitis pigmentosa Molecular Vision. 18: 2479-2496. PMID 23077406 |
0.302 |
|
| 2012 |
Seo SJ, Krebs MP, Mao H, Jones K, Conners M, Lewin AS. Pathological consequences of long-term mitochondrial oxidative stress in the mouse retinal pigment epithelium. Experimental Eye Research. 101: 60-71. PMID 22687918 DOI: 10.1016/J.Exer.2012.05.013 |
0.385 |
|
| 2012 |
Yu H, Koilkonda RD, Chou TH, Porciatti V, Ozdemir SS, Chiodo V, Boye SL, Boye SE, Hauswirth WW, Lewin AS, Guy J. Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model. Proceedings of the National Academy of Sciences of the United States of America. 109: E1238-47. PMID 22523243 DOI: 10.1073/Pnas.1119577109 |
0.463 |
|
| 2012 |
Thampi P, Rao HV, Mitter SK, Cai J, Mao H, Li H, Seo S, Qi X, Lewin AS, Romano C, Boulton ME. The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium. Plos One. 7: e34468. PMID 22509307 DOI: 10.1371/Journal.Pone.0034468 |
0.35 |
|
| 2012 |
Beltran WA, Cideciyan AV, Lewin AS, Iwabe S, Khanna H, Sumaroka A, Chiodo VA, Fajardo DS, Román AJ, Deng WT, Swider M, Alemán TS, Boye SL, Genini S, Swaroop A, et al. Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. 109: 2132-7. PMID 22308428 DOI: 10.1073/Pnas.1118847109 |
0.417 |
|
| 2012 |
Mao H, Gorbatyuk MS, Rossmiller B, Hauswirth WW, Lewin AS. Long-term rescue of retinal structure and function by rhodopsin RNA replacement with a single adeno-associated viral vector in P23H RHO transgenic mice. Human Gene Therapy. 23: 356-66. PMID 22289036 DOI: 10.1089/Hum.2011.213 |
0.411 |
|
| 2012 |
Petrs-Silva H, Yasumura D, Matthes MT, LaVail MM, Lewin AS, Hauswirth WW. Suppression of rds expression by siRNA and gene replacement strategies for gene therapy using rAAV vector. Advances in Experimental Medicine and Biology. 723: 215-23. PMID 22183336 DOI: 10.1007/978-1-4614-0631-0_29 |
0.454 |
|
| 2012 |
Mao H, Gorbatyuk MS, Hauswirth WW, Lewin AS. Gene delivery of wild-type rhodopsin rescues retinal function in an autosomal dominant retinitis pigmentosa mouse model. Advances in Experimental Medicine and Biology. 723: 199-205. PMID 22183334 DOI: 10.1007/978-1-4614-0631-0_27 |
0.418 |
|
| 2012 |
Gorbatyuk MS, Gorbatyuk OS, LaVail MM, Lin JH, Hauswirth WW, Lewin AS. Functional rescue of P23H rhodopsin photoreceptors by gene delivery. Advances in Experimental Medicine and Biology. 723: 191-7. PMID 22183333 DOI: 10.1007/978-1-4614-0631-0_26 |
0.366 |
|
| 2012 |
Verma A, Shan Z, Lei B, Yuan L, Liu X, Nakagawa T, Grant MB, Lewin AS, Hauswirth WW, Raizada MK, Li Q. ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 28-36. PMID 21792177 DOI: 10.1038/Mt.2011.155 |
0.303 |
|
| 2011 |
Mao H, James T, Schwein A, Shabashvili AE, Hauswirth WW, Gorbatyuk MS, Lewin AS. AAV delivery of wild-type rhodopsin preserves retinal function in a mouse model of autosomal dominant retinitis pigmentosa. Human Gene Therapy. 22: 567-75. PMID 21126223 DOI: 10.1089/Hum.2010.140 |
0.402 |
|
| 2011 |
Soustek MS, Falk DJ, Mah CS, Toth MJ, Schlame M, Lewin AS, Byrne BJ. Characterization of a transgenic short hairpin RNA-induced murine model of Tafazzin deficiency. Human Gene Therapy. 22: 865-71. PMID 21091282 DOI: 10.1089/Hum.2010.199 |
0.394 |
|
| 2011 |
Petrs-Silva H, Dinculescu A, Li Q, Deng WT, Pang JJ, Min SH, Chiodo V, Neeley AW, Govindasamy L, Bennett A, Agbandje-McKenna M, Zhong L, Li B, Jayandharan GR, Srivastava A, ... Lewin AS, et al. Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 293-301. PMID 21045809 DOI: 10.1038/Mt.2010.234 |
0.394 |
|
| 2010 |
Jarrett SG, Lewin AS, Boulton ME. The importance of Mitochondria in age-related and inherited eye disorders Ophthalmic Research. 44: 179-190. PMID 20829642 DOI: 10.1159/000316480 |
0.356 |
|
| 2010 |
Beltran WA, Boye SL, Boye SE, Chiodo VA, Lewin AS, Hauswirth WW, Aguirre GD. rAAV2/5 gene-targeting to rods:dose-dependent efficiency and complications associated with different promoters. Gene Therapy. 17: 1162-74. PMID 20428215 DOI: 10.1038/Gt.2010.56 |
0.425 |
|
| 2010 |
Gorbatyuk MS, Knox T, LaVail MM, Gorbatyuk OS, Noorwez SM, Hauswirth WW, Lin JH, Muzyczka N, Lewin AS. Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78. Proceedings of the National Academy of Sciences of the United States of America. 107: 5961-6. PMID 20231467 DOI: 10.1073/Pnas.0911991107 |
0.36 |
|
| 2009 |
Manfredsson FP, Burger C, Rising AC, Zuobi-Hasona K, Sullivan LF, Lewin AS, Huang J, Piercefield E, Muzyczka N, Mandel RJ. Tight Long-term dynamic doxycycline responsive nigrostriatal GDNF using a single rAAV vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1857-67. PMID 19707186 DOI: 10.1038/Mt.2009.196 |
0.325 |
|
| 2009 |
Chen B, Caballero S, Seo S, Grant MB, Lewin AS. Delivery of antioxidant enzyme genes to protect against ischemia/reperfusion-induced injury to retinal microvasculature. Investigative Ophthalmology & Visual Science. 50: 5587-95. PMID 19628743 DOI: 10.1167/Iovs.09-3633 |
0.34 |
|
| 2009 |
Guy J, Qi X, Koilkonda RD, Arguello T, Chou TH, Ruggeri M, Porciatti V, Lewin AS, Hauswirth WW. Efficiency and safety of AAV-mediated gene delivery of the human ND4 complex I subunit in the mouse visual system. Investigative Ophthalmology & Visual Science. 50: 4205-14. PMID 19387075 DOI: 10.1167/Iovs.08-3214 |
0.402 |
|
| 2009 |
Petrs-Silva H, Dinculescu A, Li Q, Min SH, Chiodo V, Pang JJ, Zhong L, Zolotukhin S, Srivastava A, Lewin AS, Hauswirth WW. High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 463-71. PMID 19066593 DOI: 10.1038/Mt.2008.269 |
0.411 |
|
| 2008 |
Li Q, Dinculescu A, Shan Z, Miller R, Pang J, Lewin AS, Raizada MK, Hauswirth WW. Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice Molecular Therapy. 16: 1688-1694. PMID 18665154 DOI: 10.1038/Mt.2008.164 |
0.42 |
|
| 2008 |
Liu J, Lewin AS, Tuli SS, Ghivizzani SC, Schultz GS, Bloom DC. Reduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA Journal of Virology. 82: 7467-7474. PMID 18508896 DOI: 10.1128/Jvi.02720-07 |
0.344 |
|
| 2008 |
Gorbatyuk MS, Hauswirth WW, Lewin AS. Gene therapy for mouse models of ADRP. Advances in Experimental Medicine and Biology. 613: 107-12. PMID 18188934 DOI: 10.1007/978-0-387-74904-4_11 |
0.371 |
|
| 2008 |
Chakraborty D, Whalen P, Lewin AS, Naash MI. In vitro analysis of ribozyme-mediated knockdown of an ADRP associated rhodopsin mutation. Advances in Experimental Medicine and Biology. 613: 97-106. PMID 18188933 DOI: 10.1007/978-0-387-74904-4_10 |
0.355 |
|
| 2008 |
Denovan-Wright EM, Rodriguez-Lebron E, Lewin AS, Mandel RJ. Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo. Neurobiology of Disease. 29: 446-55. PMID 18166484 DOI: 10.1016/J.Nbd.2007.11.003 |
0.395 |
|
| 2008 |
Andino LM, Takeda M, Kasahara H, Jakymiw A, Byrne BJ, Lewin AS. AAV-mediated knockdown of phospholamban leads to improved contractility and calcium handling in cardiomyocytes. The Journal of Gene Medicine. 10: 132-42. PMID 18064719 DOI: 10.1002/Jgm.1131 |
0.728 |
|
| 2007 |
Andino LM, Conlon TJ, Porvasnik SL, Boye SL, Hauswirth WW, Lewin AS. Rapid, widespread transduction of the murine myocardium using self-complementary Adeno-associated virus. Genetic Vaccines and Therapy. 5: 13. PMID 18070352 DOI: 10.1186/1479-0556-5-13 |
0.765 |
|
| 2007 |
Qi X, Sun L, Lewin AS, Hauswirth WW, Guy J. Long-term suppression of neurodegeneration in chronic experimental optic neuritis: Antioxidant gene therapy Investigative Ophthalmology and Visual Science. 48: 5360-5370. PMID 18055782 DOI: 10.1167/Iovs.07-0254 |
0.357 |
|
| 2007 |
Justilien V, Pang JJ, Renganathan K, Zhan X, Crabb JW, Kim SR, Sparrow JR, Hauswirth WW, Lewin AS. SOD2 knockdown mouse model of early AMD. Investigative Ophthalmology & Visual Science. 48: 4407-20. PMID 17898259 DOI: 10.1167/Iovs.07-0432 |
0.72 |
|
| 2007 |
Aarnisalo AA, Pietola L, Joensuu J, Isosomppi J, Aarnisalo P, Dinculescu A, Lewin AS, Flannery J, Hauswirth WW, Sankila EM, Jero J. Anti-clarin-1 AAV-delivered ribozyme induced apoptosis in the mouse cochlea Hearing Research. 230: 9-16. PMID 17493778 DOI: 10.1016/J.Heares.2007.03.004 |
0.379 |
|
| 2007 |
Han Z, Gorbatyuk M, Thomas J, Lewin AS, Srivastava A, Stacpoole PW. Down-regulation of expression of rat pyruvate dehydrogenase E1alpha gene by self-complementary adeno-associated virus-mediated small interfering RNA delivery. Mitochondrion. 7: 253-9. PMID 17392036 DOI: 10.1016/J.Mito.2007.02.003 |
0.403 |
|
| 2007 |
Qi X, Sun L, Hauswirth WW, Lewin AS, Guy J. Use of mitochondrial antioxidant defenses for rescue of cells with a leber hereditary optic neuropathy-causing mutation Archives of Ophthalmology. 125: 268-272. PMID 17296905 DOI: 10.1001/Archopht.125.2.268 |
0.401 |
|
| 2007 |
Gorbatyuk M, Justilien V, Liu J, Hauswirth WW, Lewin AS. Suppression of mouse rhodopsin expression in vivo by AAV mediated siRNA delivery Vision Research. 47: 1202-1208. PMID 17292939 DOI: 10.1016/J.Visres.2006.11.026 |
0.734 |
|
| 2007 |
Qi X, Lewin AS, Sun L, Hauswirth WW, Guy J. Suppression of mitochondrial oxidative stress provides long-term neuroprotection in experimental optic neuritis Investigative Ophthalmology and Visual Science. 48: 681-691. PMID 17251466 DOI: 10.1167/Iovs.06-0553 |
0.361 |
|
| 2007 |
Qi X, Sun L, Lewin AS, Hauswirth WW, Guy J. The mutant human ND4 subunit of complex I induces optic neuropathy in the mouse Investigative Ophthalmology and Visual Science. 48: 1-10. PMID 17197509 DOI: 10.1167/Iovs.06-0789 |
0.4 |
|
| 2007 |
Gorbatyuk M, Justilien V, Liu J, Hauswirth WW, Lewin AS. Preservation of photoreceptor morphology and function in P23H rats using an allele independent ribozyme Experimental Eye Research. 84: 44-52. PMID 17083931 DOI: 10.1016/J.Exer.2006.08.014 |
0.718 |
|
| 2006 |
Qi X, Lewin AS, Sun L, Hauswirth WW, Guy J. Mitochondrial protein nitration primes neurodegeneration in experimental autoimmune encephalomyelitis Journal of Biological Chemistry. 281: 31950-31962. PMID 16920708 DOI: 10.1074/Jbc.M603717200 |
0.362 |
|
| 2006 |
Manfredsson FP, Lewin AS, Mandel RJ. RNA knockdown as a potential therapeutic strategy in Parkinson's disease. Gene Therapy. 13: 517-24. PMID 16267570 DOI: 10.1038/Sj.Gt.3302669 |
0.315 |
|
| 2006 |
Liu J, Tuli SS, Bloom DC, Schultz GS, Ghivizzani SC, Lewin AS. 801. RNA Gene Therapy Targeting Herpes Simplex Virus Molecular Therapy. 13: S310. DOI: 10.1016/J.Ymthe.2006.08.890 |
0.394 |
|
| 2006 |
Andino LM, Byrne BJ, Kasahara H, Lewin AS. 709. Adeno-Associated Virus Delivery of siRNAs Leads to a Reduction in Phospholamban Levels Molecular Therapy. 13: S274. DOI: 10.1016/J.Ymthe.2006.08.788 |
0.773 |
|
| 2006 |
Han Z, Gorbatyuk M, Lewin A, Srivastava A, Stacpoole P. 325. In Vitro Gene Knockdown of Rat Pyruvate Dehydrogenase E1 α mRNA by Self- Complementary Adeno-Associated Virus-Mediated Small Interfering RNA Delivery Molecular Therapy. 13: S124. DOI: 10.1016/J.Ymthe.2006.08.382 |
0.389 |
|
| 2006 |
Manfredsson FP, Mandel RJ, Zolotukhin S, Lewin AS. 1032. rAAV Mediated Knock-Down of Tyrosine Hydroxylase in the Substantia Nigra Using a pol II Transcribed siRNA Molecular Therapy. 13: S396. DOI: 10.1016/J.Ymthe.2006.08.1127 |
0.367 |
|
| 2005 |
Teusner JT, Lewin AS, Hauswirth WW. Down-regulation of rhodopsin gene expression by AAV-vectored short interfering RNA Advances in Experimental Medicine and Biology. 572: 233-238. PMID 17249579 DOI: 10.1007/0-387-32442-9_33 |
0.332 |
|
| 2005 |
Lewin AS, Glazer PM, Milstone LM. Gene therapy for autosomal dominant disorders of keratin. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 10: 47-61. PMID 16250209 DOI: 10.1111/J.1087-0024.2005.10207.X |
0.367 |
|
| 2005 |
Liu J, Timmers AM, Lewin AS, Hauswirth WW. Ribozyme knockdown of the gamma-subunit of rod cGMP phosphodiesterase alters the ERG and retinal morphology in wild-type mice. Investigative Ophthalmology & Visual Science. 46: 3836-44. PMID 16186371 DOI: 10.1167/Iovs.04-1283 |
0.356 |
|
| 2005 |
Rodriguez-Lebron E, Denovan-Wright EM, Nash K, Lewin AS, Mandel RJ. Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 618-33. PMID 16019264 DOI: 10.1016/J.Ymthe.2005.05.006 |
0.358 |
|
| 2005 |
Gorbatyuk MS, Timmers AM, Jijing P, Hauswirth WW, Lewin AS. 1080. rAAV Delivered Ribozyme Targeting Mouse Opsin to Rescue Vision in P23H Rats Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.627 |
0.357 |
|
| 2005 |
Rodriguez E, Denovan-Wright E, Lewin AS, Mandel RJ. 954. Demonstration of In Vivo Off-Targeting Using rAAV-Delivered Ribozymes and shRNA Molecules in a Mouse Model of Huntington's Disease Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.497 |
0.396 |
|
| 2005 |
Liu J, Tuli SS, Bloom DC, Schultz GS, Hauswirth WW, Lewin AS. 861. AAV Gene Delivery for the Cornea Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.404 |
0.411 |
|
| 2005 |
Justilien V, Pang J, Hauswirth WW, Lewin AS. 741. AAV Delivered Ribozymes to Recapitulate the Early Stages of Age Related Macular Degeneration Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.281 |
0.697 |
|
| 2005 |
Charron CE, Perera OP, Porvasnik SL, Blackburn M, Lewin AS, Laipis PJ. 422. Dominant-Negative Interference in the Pahenu2 Mouse Model of PKU: Effectiveness of Vectors Expressing Either Modified Forms of Phenylalanine Hydroxylase (PAH) or Ribozymes Plus a Hardened PAH mRNA Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.424 |
0.373 |
|
| 2005 |
Manfredsson FP, Lewin AS, Muzyczka N, Burger C, Mandel RJ. 59. rAAV-Mediated Nigral Parkin Over-Expression Is Neuroprotective in the 6-OHDA Rat Model of Parkinson's Disease Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.087 |
0.347 |
|
| 2005 |
Rodriguez E, Denovan-Wright E, Nash K, Lewin AS, Mandel RJ. 53. Post-Transcriptional Suppression of Striatal Mutant Huntingtin Leads to Mild Phenotypic Improvements in the R6/1 Mouse Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.081 |
0.362 |
|
| 2004 |
Qi X, Lewin AS, Sun L, Hauswirth WW, Guy J. SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I Annals of Neurology. 56: 182-191. PMID 15293270 DOI: 10.1002/Ana.20175 |
0.39 |
|
| 2004 |
Fritz JJ, Gorbatyuk M, Lewin AS, Hauswirth WW. Design and validation of therapeutic hammerhead ribozymes for autosomal dominant diseases. Methods in Molecular Biology (Clifton, N.J.). 252: 221-36. PMID 15017052 DOI: 10.1385/1-59259-746-7:221 |
0.365 |
|
| 2004 |
Hauswirth WW, Li Q, Raisler B, Timmers AM, Berns KI, Flannery JG, LaVail MM, Lewin AS. Range of retinal diseases potentially treatable by AAV-vectored gene therapy. Novartis Foundation Symposium. 255: 179-88; discussion 1. PMID 14750604 DOI: 10.1002/0470092645.Ch14 |
0.417 |
|
| 2004 |
Charron CE, Lewin AS, Laipis PJ. 877. Evidence for dominant-negative interference in the Pahenu2 mouse model of PKU Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.783 |
0.38 |
|
| 2004 |
Conlon TJ, Beattie SG, Snyder CW, Lewin AS, Flotte TR. 875. Ribozyme Approaches towards Down-Regulation of Pi|[ast]|Z Mutant Human A-1 Anti-Trypsin Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.782 |
0.379 |
|
| 2004 |
Gorbatyuk M, Pang JJ, Hauswirth WW, Lewin AS. 654. rAAV Mediated Ribozyme Delivery Targeting Mouse Rhodopsin Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.600 |
0.412 |
|
| 2004 |
Manfredsson FP, Lewin AS, Mandel RJ. 529. rAAV mediated parkin expression confers some protection in the rat 6-OHDA lesion model Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.476 |
0.327 |
|
| 2004 |
Bongorno JA, Guy J, Lewin AS. 437. Developing a Mouse Model of the Mitochondrial NARP Syndrome Using AAV-Ribozymes for ATP6 Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.410 |
0.723 |
|
| 2004 |
Qi X, Sun L, Guy J, Hauswirth WW, Lewin AS. 212. AAV-Mediated Gene Transfer Protects Against Mitochondrial Optic Neuropathy in Mice Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.153 |
0.449 |
|
| 2003 |
Afzal A, Shaw LC, Caballero S, Spoerri PE, Lewin AS, Zeng D, Belardinelli L, Grant MB. Reduction in preretinal neovascularization by ribozymes that cleave the A2B adenosine receptor mRNA Circulation Research. 93: 500-506. PMID 12919950 DOI: 10.1161/01.Res.0000091260.78959.Bc |
0.314 |
|
| 2003 |
Cheng S, Clancy CJ, Checkley MA, Handfield M, Hillman JD, Progulske-Fox A, Lewin AS, Fidel PL, Nguyen MH. Identification of Candida albicans genes induced during thrush offers insight into pathogenesis. Molecular Microbiology. 48: 1275-88. PMID 12787355 DOI: 10.1046/J.1365-2958.2003.03521.X |
0.769 |
|
| 2003 |
Qi X, Lewin AS, Hauswirth WW, Guy J. Optic neuropathy induced by reductions in mitochondrial superoxide dismutase Investigative Ophthalmology and Visual Science. 44: 1088-1096. PMID 12601034 DOI: 10.1167/Iovs.02-0864 |
0.39 |
|
| 2003 |
Qi X, Lewin AS, Hauswirth WW, Guy J. Suppression of complex I gene expression induces optic neuropathy Annals of Neurology. 53: 198-205. PMID 12557286 DOI: 10.1002/Ana.10426 |
0.4 |
|
| 2002 |
Fritz JJ, Lewin A, Hauswirth W, Agarwal A, Grant M, Shaw L. Development of hammerhead ribozymes to modulate endogenous gene expression for functional studies. Methods (San Diego, Calif.). 28: 276-85. PMID 12413427 DOI: 10.1016/S1046-2023(02)00233-5 |
0.383 |
|
| 2002 |
Guy J, Qi X, Pallotti F, Schon EA, Manfredi G, Carelli V, Martinuzzi A, Hauswirth WW, Lewin AS. Rescue of a mitochondrial deficiency causing Leber Hereditary Optic Neuropathy. Annals of Neurology. 52: 534-42. PMID 12402249 DOI: 10.1002/Ana.10354 |
0.391 |
|
| 2002 |
Fritz JJ, White DA, Lewin AS, Hauswirth WW. Designing and characterizing hammerhead ribozymes for use in AAV vector-mediated retinal gene therapies. Methods in Enzymology. 346: 358-77. PMID 11883079 DOI: 10.1016/S0076-6879(02)46066-1 |
0.363 |
|
| 2001 |
Hauswirth WW, Shaw LC, Whalen PO, Fritz JJ, White DA, Lewin AS. Inhibition of gene expression by ribozymes. Methods in Molecular Medicine. 47: 105-24. PMID 21394581 DOI: 10.1385/1-59259-085-3:105 |
0.317 |
|
| 2001 |
Lewin AS, Hauswirth WW. Ribozyme gene therapy: Applications for molecular medicine Trends in Molecular Medicine. 7: 221-228. PMID 11325634 DOI: 10.1016/S1471-4914(01)01965-7 |
0.367 |
|
| 2001 |
Hauswirth WW, LaVail MM, Flannery JG, Lewin AS. Viral-vectored ribozymes as therapy for autosomal dominant retinal disease Clinical Neuroscience Research. 1: 118-126. DOI: 10.1016/S1566-2772(00)00010-4 |
0.413 |
|
| 2000 |
Hauswirth WW, Lewin AS. Ribozyme uses in retinal gene therapy Progress in Retinal and Eye Research. 19: 689-710. PMID 11029552 DOI: 10.1016/S1350-9462(00)00007-0 |
0.405 |
|
| 2000 |
LaVail MM, Yasumura D, Matthes MT, Drenser KA, Flannery JG, Lewin AS, Hauswirth WW. Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy. Proceedings of the National Academy of Sciences of the United States of America. 97: 11488-93. PMID 11005848 DOI: 10.1073/Pnas.210319397 |
0.37 |
|
| 2000 |
Hauswirth WW, LaVail MM, Flannery JG, Lewin AS. Ribozyme gene therapy for autosomal dominant retinal disease. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 38: 147-53. PMID 10834402 DOI: 10.1515/Cclm.2000.022 |
0.417 |
|
| 2000 |
Shaw LC, Whalen PO, Drenser KA, Yan W, Hauswirth WW, Lewin AS. Ribozymes in treatment of inherited retinal disease. Methods in Enzymology. 316: 761-76. PMID 10800713 DOI: 10.1016/S0076-6879(00)16761-8 |
0.381 |
|
| 2000 |
Hauswirth WW, Lewin AS, Zolotukhin S, Muzyczka N. Production and purification of recombinant adeno-associated virus. Methods in Enzymology. 316: 743-61. PMID 10800712 DOI: 10.1016/S0076-6879(00)16760-6 |
0.317 |
|
| 1999 |
Tirupati HK, Shaw LC, Lewin AS. An RNA binding motif in the Cbp2 protein required for protein-stimulated RNA catalysis Journal of Biological Chemistry. 274: 30393-30401. PMID 10521416 DOI: 10.1074/Jbc.274.43.30393 |
0.318 |
|
| 1999 |
Owen R, Lewin AS, Wang J, Hauswirth WW, Stacpoole PW, Flotte TR. Adeno-Associated Virus (AAV)-Based Gene Therapy for Defects in Oxidative Metabolism Pediatric Research. 45: 140A-140A. DOI: 10.1203/00006450-199904020-00833 |
0.316 |
|
| 1998 |
Lewin AS, Drenser KA, Hauswirth WW, Nishikawa S, Yasumura D, Flannery JG, LaVail MM. Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Nature Medicine. 4: 967-71. PMID 9701253 DOI: 10.1038/Nm0898-967 |
0.436 |
|
| 1997 |
Shaw LC, Lewin AS. The Cbp2 protein stimulates the splicing of the ω intron of yeast mitochondria Nucleic Acids Research. 25: 1597-1604. PMID 9092668 DOI: 10.1093/Nar/25.8.1597 |
0.365 |
|
| 1995 |
Lewin AS, Thomas J, Tirupati HK. Cotranscriptional splicing of a group I intron is facilitated by the Cbp2 protein Molecular and Cellular Biology. 15: 6971-6978. PMID 8524264 DOI: 10.1128/Mcb.15.12.6971 |
0.331 |
|
| 1995 |
Shaw LC, Lewin AS. Protein-induced folding of a group I intron in cytochrome b pre-mRNA Journal of Biological Chemistry. 270: 21552-21562. PMID 7665568 DOI: 10.1074/Jbc.270.37.21552 |
0.303 |
|
| 1994 |
Moran JV, Mecklenburg KL, Sass P, Belcher SM, Mahnke D, Lewin A, Perlman P. Splicing defective mutants of the COXI gene of yeast mitochondrial DNA: Initial definition of the maturase domain of the group II intron AI2 Nucleic Acids Research. 22: 2057-2064. PMID 8029012 DOI: 10.1093/Nar/22.11.2057 |
0.35 |
|
| 1992 |
Singh KK, Small GM, Lewin AS. Alternative topogenic signals in peroxisomal citrate synthase of Saccharomyces cerevisiae Molecular and Cellular Biology. 12: 5593-5599. PMID 1448089 DOI: 10.1128/Mcb.12.12.5593 |
0.337 |
|
| 1992 |
Ritchings BW, Lewin AS. Mutational evidence for competition between the P1 and the P10 helices of a mitochondrial group I intron Nucleic Acids Research. 20: 2349-2353. PMID 1375737 DOI: 10.1093/Nar/20.9.2349 |
0.304 |
|
| 1990 |
Small GM, Lewin AS. Protein targeting to peroxisomes Biochemical Society Transactions. 18: 85-87. PMID 2185098 DOI: 10.1042/Bst0180085 |
0.339 |
|
| 1990 |
Lewin AS, Hines V, Small GM. Citrate synthase encoded by the CIT2 gene of Saccharomyces cerevisiae is peroxisomal Molecular and Cellular Biology. 10: 1399-1405. PMID 2181273 DOI: 10.1128/Mcb.10.4.1399 |
0.377 |
|
| 1988 |
Partono S, Lewin AS. Autocatalytic activities of intron 5 of the cob gene of yeast mitochondria Molecular and Cellular Biology. 8: 2562-2571. PMID 3043183 DOI: 10.1128/Mcb.8.6.2562 |
0.329 |
|
| 1979 |
Lewin AS, Morimoto R, Rabinowitz M. Stable heterogeneity of mitochondrial DNA in grande and petite strains of S. cerevisiae Plasmid. 2: 474-484. PMID 384424 DOI: 10.1016/0147-619X(79)90031-3 |
0.624 |
|
| 1979 |
Locker J, Lewin A, Rabinowitz M. The structure and organization of mitochondrial DNA from petite yeast. Plasmid. 2: 155-81. PMID 377320 DOI: 10.1016/0147-619X(79)90036-2 |
0.514 |
|
| 1978 |
Morimoto R, Merten S, Lewin A, Martin NC, Rabinowitz M. Physical mapping of genes on yeast mitochondrial DNA: localization of antibiotic resistance loci, and rRNA and tRNA genes. Molecular & General Genetics : Mgg. 163: 241-55. PMID 355852 DOI: 10.1007/Bf00271954 |
0.67 |
|
| 1977 |
Morimoto R, Lewin A, Rabinowitz M. Restriction cleavage map of mitochonrial DNA from the yeast Saccharomyces cerevisiae. Nucleic Acids Research. 4: 2331-51. PMID 333388 DOI: 10.1093/Nar/4.7.2331 |
0.65 |
|
| 1975 |
Morimoto R, Lewin A, Hsu HJ, Rabinowitz M, Fukuhara H. Restriction endonuclease analysis of mitochondrial DNA from grande and genetically characterized cytoplasmic petite clones of Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 72: 3868-3872. PMID 1105566 DOI: 10.1073/Pnas.72.10.3868 |
0.655 |
|
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