Peter C. Harris - Publications

Affiliations: 
Biochemistry and Molecular Biology College of Medicine - Mayo Clinic 
Area:
Molecular Biology, Genetics, Human Development

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Martin WP, Vaughan LE, Yoshida K, Takahashi N, Edwards ME, Metzger A, Senum SR, Masyuk TV, LaRusso NF, Griffin MD, El-Zoghby Z, Harris PC, Kremers WK, Nagorney DM, Kamath PS, et al. Bacterial Cholangitis in Autosomal Dominant Polycystic Kidney and Liver Disease. Mayo Clinic Proceedings. Innovations, Quality & Outcomes. 3: 149-159. PMID 31193902 DOI: 10.1016/j.mayocpiqo.2019.03.004  0.44
2019 McNicholas BA, Kotaro Y, Martin W, Sharma A, Kamath PS, Edwards ME, Kremers WK, Chari ST, Torres VE, Harris PC, Takahashi N, Hogan MC. Pancreatic Cysts and Intraductal Papillary Mucinous Neoplasm in Autosomal Dominant Polycystic Kidney Disease. Pancreas. 48: 698-705. PMID 31091218 DOI: 10.1097/MPA.0000000000001306  0.44
2019 Bae KT, Zhou W, Shen C, Landsittel DP, Wu Z, Tao C, Chapman AB, Torres VE, Yu ASL, Mrug M, Bennett WM, Harris PC. Growth Pattern of Kidney Cyst Number and Volume in Autosomal Dominant Polycystic Kidney Disease. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 31088850 DOI: 10.2215/CJN.10360818  0.44
2019 Yu ASL, Shen C, Landsittel DP, Grantham JJ, Cook LT, Torres VE, Chapman AB, Bae KT, Mrug M, Harris PC, Rahbari-Oskoui FF, Shi T, Bennett WM. Long-term trajectory of kidney function in autosomal-dominant polycystic kidney disease. Kidney International. PMID 30922668 DOI: 10.1016/j.kint.2018.12.023  0.44
2019 Yoshida K, Takahashi N, King BF, Kawashima A, Harris PC, Cornell LD, Cornec-Le Gall E, Inoue D, Mizushima I, Kawano M, Thervet E, de Cotret PR, Torres VE. Multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney: CT and MRI findings and clinical characteristic. European Radiology. PMID 30806804 DOI: 10.1007/s00330-019-06057-3  0.44
2019 Torres VE, Harris PC. Progress in the understanding of polycystic kidney disease. Nature Reviews. Nephrology. PMID 30607031 DOI: 10.1038/s41581-018-0108-1  0.44
2018 McKenzie KA, El Ters M, Torres VE, Harris PC, Chapman AB, Mrug M, Rahbari-Oskoui FF, Bae KT, Landsittel DP, Bennett WM, Yu ASL, Mahnken JD. Relationship between caffeine intake and autosomal dominant polycystic kidney disease progression: a retrospective analysis using the CRISP cohort. Bmc Nephrology. 19: 378. PMID 30591038 DOI: 10.1186/s12882-018-1182-0  0.44
2018 Bergmann C, Guay-Woodford LM, Harris PC, Horie S, Peters DJM, Torres VE. Polycystic kidney disease. Nature Reviews. Disease Primers. 4: 50. PMID 30523303 DOI: 10.1038/s41572-018-0047-y  0.44
2018 Kleczko EK, Marsh KH, Tyler LC, Furgeson SB, Bullock BL, Altmann CJ, Miyazaki M, Gitomer BY, Harris PC, Weiser-Evans MCM, Chonchol MB, Clambey ET, Nemenoff RA, Hopp K. CD8 T cells modulate autosomal dominant polycystic kidney disease progression. Kidney International. PMID 30249452 DOI: 10.1016/j.kint.2018.06.025  1
2018 Chebib FT, Perrone RD, Chapman AB, Dahl NK, Harris PC, Mrug M, Mustafa RA, Rastogi A, Watnick T, Yu ASL, Torres VE. A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan. Journal of the American Society of Nephrology : Jasn. PMID 30228150 DOI: 10.1681/ASN.2018060590  0.44
2018 Boczek NJ, Hopp K, Benoit L, Kraft D, Cousin MA, Blackburn PR, Madsen CD, Oliver GR, Nair AA, Na J, Bianchi DW, Beek G, Harris PC, Pichurin P, Klee EW. Characterization of three ciliopathy pedigrees expands the phenotype associated with biallelic C2CD3 variants. European Journal of Human Genetics : Ejhg. PMID 30097616 DOI: 10.1038/s41431-018-0222-3  1
2018 Edwards ME, Chebib FT, Irazabal MV, Ofstie TG, Bungum LA, Metzger AJ, Senum SR, Hogan MC, El-Zoghby ZM, Kline TL, Harris PC, Czerwiec FS, Torres VE. Long-Term Administration of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 30026287 DOI: 10.2215/CJN.01520218  0.44
2018 Cornec-Le Gall E, Olson RJ, Besse W, Heyer CM, Gainullin VG, Smith JM, Audrézet MP, Hopp K, Porath B, Shi B, Baheti S, Senum SR, Arroyo J, Madsen CD, Férec C, ... ... Harris PC, et al. Monoallelic Mutations to DNAJB11 Cause Atypical Autosomal-Dominant Polycystic Kidney Disease. American Journal of Human Genetics. PMID 29706351 DOI: 10.1016/j.ajhg.2018.03.013  1
2018 Brosnahan GM, Abebe KZ, Moore CG, Bae KT, Braun WE, Chapman AB, Flessner MF, Harris PC, Hogan MC, Perrone RD, Rahbari-Oskoui FF, Steinman TI, Torres VE, The Halt Pkd Investigators. Determinants of Progression in Early Autosomal Dominant Polycystic Kidney Disease - Is it Blood Pressure or Renin-Angiotensin-Aldosterone-System Blockade? Current Hypertension Reviews. PMID 29564978 DOI: 10.2174/1573402114666180322110209  0.44
2018 Cornec-Le Gall E, Chebib FT, Madsen CD, Senum SR, Heyer CM, Lanpher BC, Patterson MC, Albright RC, Yu AS, Torres VE, Harris PC. The Value of Genetic Testing in Polycystic Kidney Diseases Illustrated by a Family With PKD2 and COL4A1 Mutations. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 29395486 DOI: 10.1053/j.ajkd.2017.11.015  0.44
2018 Brosnahan GM, Abebe KZ, Moore CG, Rahbari-Oskoui FF, Bae KT, Grantham JJ, Schrier RW, Braun WE, Chapman AB, Flessner MF, Harris PC, Hogan MC, Perrone RD, Miskulin DC, Steinman TI, et al. Patterns of Kidney Function Decline in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis From the HALT-PKD Trials. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 29306517 DOI: 10.1053/j.ajkd.2017.10.023  0.44
2017 Yu ASL, Shen C, Landsittel DP, Harris PC, Torres VE, Mrug M, Bae KT, Grantham JJ, Rahbari-Oskoui FF, Flessner MF, Bennett WM, Chapman AB. Baseline total kidney volume and the rate of kidney growth are associated with chronic kidney disease progression in Autosomal Dominant Polycystic Kidney Disease. Kidney International. PMID 29290310 DOI: 10.1016/j.kint.2017.09.027  0.44
2017 Chebib FT, Hogan MC, El-Zoghby ZM, Irazabal MV, Senum SR, Heyer CM, Madsen CD, Cornec-Le Gall E, Behfar A, Harris PC, Torres VE. Autosomal Dominant Polycystic Kidney Patients May Be Predisposed to Various Cardiomyopathies. Kidney International Reports. 2: 913-923. PMID 29270497 DOI: 10.1016/j.ekir.2017.05.014  0.44
2017 Braun WE, Abebe KZ, Brosnahan G, Patterson CG, Chapman AB, Harris PC, Hogan MC, Perrone RD, Torres VE, Miskulin DC, Steinman TI, Winklhofer FT, Rahbari-Oskoui FF, Czarnecki PG, Bae KT, et al. ADPKD Progression in Patients With No Apparent Family History and No Mutation Detected by Sanger Sequencing. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 29203126 DOI: 10.1053/j.ajkd.2017.09.008  0.44
2017 Nowak KL, You Z, Gitomer B, Brosnahan G, Torres VE, Chapman AB, Perrone RD, Steinman TI, Abebe KZ, Rahbari-Oskoui FF, Yu ASL, Harris PC, Bae KT, Hogan M, Miskulin D, et al. Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 29118087 DOI: 10.1681/ASN.2017070819  0.44
2017 Cornec-Le Gall E, Torres VE, Harris PC. Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases. Journal of the American Society of Nephrology : Jasn. PMID 29038287 DOI: 10.1681/ASN.2017050483  0.44
2017 Cornec-Le Gall E, Blais JD, Irazabal MV, Devuyst O, Gansevoort RT, Perrone RD, Chapman AB, Czerwiec FS, Ouyang J, Heyer CM, Senum SR, Le Meur Y, Torres VE, Harris PC. Can we further enrich autosomal dominant polycystic kidney disease clinical trials for rapidly progressive patients? Application of the PROPKD score in the TEMPO trial. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 28992127 DOI: 10.1093/ndt/gfx188  0.44
2017 Wang X, Yamada S, LaRiviere WB, Ye H, Bakeberg JL, Irazabal MV, Chebib FT, van Deursen J, Harris PC, Sussman CR, Behfar A, Ward CJ, Torres VE. Generation and phenotypic characterization of Pde1a mutant mice. Plos One. 12: e0181087. PMID 28750036 DOI: 10.1371/journal.pone.0181087  0.6
2017 Kline TL, Edwards ME, Garg I, Irazabal MV, Korfiatis P, Harris PC, King BF, Torres VE, Venkatesh SK, Erickson BJ. Quantitative MRI of kidneys in renal disease. Abdominal Radiology (New York). PMID 28660330 DOI: 10.1007/s00261-017-1236-y  0.44
2017 Ye H, Wang X, Constans MM, Sussman CR, Chebib F, Irazabal MV, Young WF, Harris PC, Kirschner LS, Torres VE. The Regulatory 1α Subunit of Protein Kinase A Modulates Renal Cystogenesis. American Journal of Physiology. Renal Physiology. ajprenal.00119.2017. PMID 28615245 DOI: 10.1152/ajprenal.00119.2017  0.44
2017 Kline TL, Korfiatis P, Edwards ME, Blais JD, Czerwiec FS, Harris PC, King BF, Torres VE, Erickson BJ. Performance of an Artificial Multi-observer Deep Neural Network for Fully Automated Segmentation of Polycystic Kidneys. Journal of Digital Imaging. PMID 28550374 DOI: 10.1007/s10278-017-9978-1  0.44
2017 Kline TL, Korfiatis P, Edwards ME, Bae KT, Yu A, Chapman AB, Mrug M, Grantham JJ, Landsittel D, Bennett WM, King BF, Harris PC, Torres VE, Erickson BJ. Image texture features predict renal function decline in patients with autosomal dominant polycystic kidney disease. Kidney International. PMID 28532709 DOI: 10.1016/j.kint.2017.03.026  0.44
2017 Brosnahan G, Abebe KZ, Rahbari-Oskoui FF, Patterson CG, Bae KT, Schrier RW, Braun WE, Chapman AB, Flessner MF, Harris PC, Perrone RD, Steinman TI, Torres VE, The Halt Pkd Investigators. Effect of statin therapy on the progression of autosomal dominant polycystic kidney disease. A secondary analysis of the HALT PKD trials. Current Hypertension Reviews. PMID 28460625 DOI: 10.2174/1573402113666170427142815  0.44
2017 Holditch SJ, Schreiber CA, Harris PC, LaRusso NF, Ramirez-Alvarado M, Cataliotti A, Torres VE, Ikeda Y. B-type natriuretic peptide overexpression ameliorates hepatorenal fibrocystic disease in a rat model of polycystic kidney disease. Kidney International. PMID 28416225 DOI: 10.1016/j.kint.2017.02.017  0.44
2017 Yin M, Glaser KJ, Manduca A, Mounajjed T, Malhi H, Simonetto DA, Wang R, Yang L, Mao SA, Glorioso JM, Elgilani FM, Ward CJ, Harris PC, Nyberg SL, Shah VH, et al. Distinguishing between Hepatic Inflammation and Fibrosis with MR Elastography. Radiology. 160622. PMID 28128707 DOI: 10.1148/radiol.2017160622  0.6
2016 Irazabal MV, Blais JD, Perrone RD, Gansevoort RT, Chapman AB, Devuyst O, Higashihara E, Harris PC, Zhou W, Ouyang J, Czerwiec FS, Torres VE. Prognostic Enrichment Design in Clinical Trials for Autosomal Dominant Polycystic Kidney Disease: The TEMPO 3:4 Clinical Trial. Kidney International Reports. 1: 213-220. PMID 29142926 DOI: 10.1016/j.ekir.2016.08.001  0.44
2016 Wang X, Anglani F, Beara-Lasic L, Mehta AJ, Vaughan LE, Herrera Hernandez L, Cogal A, Scheinman SJ, Ariceta G, Isom R, Copelovitch L, Enders FT, Del Prete D, Vezzoli G, Paglialonga F, ... Harris PC, et al. Glomerular Pathology in Dent Disease and Its Association with Kidney Function. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 27697782 DOI: 10.2215/CJN.03710416  0.44
2016 Irazabal MV, Abebe KZ, Bae KT, Perrone RD, Chapman AB, Schrier RW, Yu AS, Braun WE, Steinman TI, Harris PC, Flessner MF, Torres VE. Prognostic enrichment design in clinical trials for autosomal dominant polycystic kidney disease: the HALT-PKD clinical trial. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 27484667 DOI: 10.1093/ndt/gfw294  0.44
2016 Porath B, Gainullin VG, Cornec-Le Gall E, Dillinger EK, Heyer CM, Hopp K, Edwards ME, Madsen CD, Mauritz SR, Banks CJ, Baheti S, Reddy B, Herrero JI, Bañales JM, Hogan MC, ... ... Harris PC, et al. Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease. American Journal of Human Genetics. 98: 1193-1207. PMID 27259053 DOI: 10.1016/j.ajhg.2016.05.004  1
2016 Kim B, King BF, Vrtiska TJ, Irazabal MV, Torres VE, Harris PC. Inherited renal cystic diseases. Abdominal Radiology (New York). PMID 27167233 DOI: 10.1007/s00261-016-0754-3  0.44
2016 Zhang Q, Li Y, Zhang Y, Torres VE, Harris PC, Ling K, Hu J. GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119. Scientific Reports. 6: 24534. PMID 27102355 DOI: 10.1038/srep24534  0.44
2016 Chebib FT, Jung Y, Heyer CM, Irazabal MV, Hogan MC, Harris PC, Torres VE, El-Zoghby ZM. Effect of genotype on the severity and volume progression of polycystic liver disease in autosomal dominant polycystic kidney disease. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 26932689 DOI: 10.1093/ndt/gfw008  0.44
2016 Heyer CM, Sundsbak JL, Abebe KZ, Chapman AB, Torres VE, Grantham JJ, Bae KT, Schrier RW, Perrone RD, Braun WE, Steinman TI, Mrug M, Yu AS, Brosnahan G, Hopp K, ... ... Harris PC, et al. Predicted Mutation Strength of Nontruncating PKD1 Mutations Aids Genotype-Phenotype Correlations in Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 26823553 DOI: 10.1681/ASN.2015050583  1
2015 Hogan MC, Lieske JC, Lienczewski CC, Nesbitt LL, Wickman LT, Heyer CM, Harris PC, Ward CJ, Sundsbak JL, Manganelli L, Ju W, Kopp JB, Nelson PJ, Adler SG, Reich HN, et al. Strategy and rationale for urine collection protocols employed in the NEPTUNE study. Bmc Nephrology. 16: 190. PMID 26577187 DOI: 10.1186/s12882-015-0185-3  1
2015 Warner G, Hein KZ, Nin V, Edwards M, Chini CC, Hopp K, Harris PC, Torres VE, Chini EN. Food Restriction Ameliorates the Development of Polycystic Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 26538633 DOI: 10.1681/ASN.2015020132  1
2015 Ye H, Wang X, Sussman CR, Hopp K, Irazabal MV, Bakeberg JL, LaRiviere WB, Manganiello VC, Voorhees CV, Zhao H, Harris PC, van Deursen J, Ward CJ, Torres VE. Modulation of Polycystic Kidney Disease Severity by Phosphodiesterase 1 and 3 Subfamilies. Journal of the American Society of Nephrology : Jasn. PMID 26374610 DOI: 10.1681/ASN.2015010057  1
2015 Moore CG, Spillane S, Simon G, Maxwell B, Rahbari-Oskoui FF, Braun WE, Chapman AB, Schrier RW, Torres VE, Perrone RD, Steinman TI, Brosnahan G, Czarnecki PG, Harris PC, Miskulin DC, et al. Closeout of the HALT-PKD trials. Contemporary Clinical Trials. 44: 48-55. PMID 26231556 DOI: 10.1016/j.cct.2015.07.017  1
2015 Ong AC, Harris PC. A polycystin-centric view of cyst formation and disease: the polycystins revisited. Kidney International. 88: 699-710. PMID 26200945 DOI: 10.1038/ki.2015.207  1
2015 Cabrera-López C, Bullich G, Martí T, Català V, Ballarín J, Bissler JJ, Harris PC, Ars E, Torra R. Insight into response to mTOR inhibition when PKD1 and TSC2 are mutated. Bmc Medical Genetics. 16: 39. PMID 26077033 DOI: 10.1186/s12881-015-0185-y  1
2015 Jung Y, Irazabal MV, Chebib FT, Harris PC, Dean PG, Prieto M, Cosio FG, El-Zoghby ZM, Torres VE. Volume regression of native polycystic kidneys after renal transplantation. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 26044834 DOI: 10.1093/ndt/gfv227  0.44
2015 Kline TL, Irazabal MV, Ebrahimi B, Hopp K, Udoji KN, Warner JD, Korfiatis P, Mishra PK, Macura SI, Venkatesh SK, Lerman LO, Harris PC, Torres VE, King BF, Erickson BJ. Utilizing magnetization transfer imaging to investigate tissue remodeling in a murine model of autosomal dominant polycystic kidney disease. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. PMID 25974140 DOI: 10.1002/mrm.25701  1
2015 Antignac C, Calvet JP, Germino GG, Grantham JJ, Guay-Woodford LM, Harris PC, Hildebrandt F, Peters DJ, Somlo S, Torres VE, Walz G, Zhou J, Yu AS. The Future of Polycystic Kidney Disease Research-As Seen By the 12 Kaplan Awardees. Journal of the American Society of Nephrology : Jasn. PMID 25952256 DOI: 10.1681/ASN.2014121192  1
2015 Ali H, Hussain N, Naim M, Zayed M, Al-Mulla F, Kehinde EO, Seaburg LM, Sundsbak JL, Harris PC. A novel PKD1 variant demonstrates a disease-modifying role in trans with a truncating PKD1 mutation in patients with autosomal dominant polycystic kidney disease. Bmc Nephrology. 16: 26. PMID 25880449 DOI: 10.1186/s12882-015-0015-7  1
2015 Chebib FT, Sussman CR, Wang X, Harris PC, Torres VE. Vasopressin and disruption of calcium signalling in polycystic kidney disease. Nature Reviews. Nephrology. PMID 25870007 DOI: 10.1038/nrneph.2015.39  1
2015 Wu M, Wang D, Zand L, Harris PC, White WM, Garovic VD, Kermott CA. Pregnancy outcomes in autosomal dominant polycystic kidney disease: a case-control study. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 1-6. PMID 25754208 DOI: 10.3109/14767058.2015.1019458  1
2015 Hopp K, Cogal AG, Bergstralh EJ, Seide BM, Olson JB, Meek AM, Lieske JC, Milliner DS, Harris PC. Phenotype-Genotype Correlations and Estimated Carrier Frequencies of Primary Hyperoxaluria. Journal of the American Society of Nephrology : Jasn. PMID 25644115 DOI: 10.1681/ASN.2014070698  1
2015 Gainullin VG, Hopp K, Ward CJ, Hommerding CJ, Harris PC. Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner. The Journal of Clinical Investigation. 125: 607-20. PMID 25574838 DOI: 10.1172/JCI76972  1
2015 Schueler M, Braun DA, Chandrasekar G, Gee HY, Klasson TD, Halbritter J, Bieder A, Porath JD, Airik R, Zhou W, LoTurco JJ, Che A, Otto EA, Böckenhauer D, Sebire NJ, ... ... Harris PC, et al. DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling. American Journal of Human Genetics. 96: 81-92. PMID 25557784 DOI: 10.1016/j.ajhg.2014.12.002  1
2015 Hopp K, Wang X, Ye H, Irazabal MV, Harris PC, Torres VE. Effects of hydration in rats and mice with polycystic kidney disease. American Journal of Physiology. Renal Physiology. 308: F261-6. PMID 25503729 DOI: 10.1152/ajprenal.00345.2014  1
2015 Hogan MC, Bakeberg JL, Gainullin VG, Irazabal MV, Harmon AJ, Lieske JC, Charlesworth MC, Johnson KL, Madden BJ, Zenka RM, McCormick DJ, Sundsbak JL, Heyer CM, Torres VE, Harris PC, et al. Identification of Biomarkers for PKD1 Using Urinary Exosomes. Journal of the American Society of Nephrology : Jasn. 26: 1661-70. PMID 25475747 DOI: 10.1681/ASN.2014040354  1
2015 Pei Y, Hwang YH, Conklin J, Sundsbak JL, Heyer CM, Chan W, Wang K, He N, Rattansingh A, Atri M, Harris PC, Haider MA. Imaging-based diagnosis of autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 26: 746-53. PMID 25074509 DOI: 10.1681/ASN.2014030297  1
2015 Hopp K, Hommerding CJ, Wang X, Ye H, Harris PC, Torres VE. Tolvaptan plus pasireotide shows enhanced efficacy in a PKD1 model. Journal of the American Society of Nephrology : Jasn. 26: 39-47. PMID 24994926 DOI: 10.1681/ASN.2013121312  1
2015 Irazabal MV, Rangel LJ, Bergstralh EJ, Osborn SL, Harmon AJ, Sundsbak JL, Bae KT, Chapman AB, Grantham JJ, Mrug M, Hogan MC, El-Zoghby ZM, Harris PC, Erickson BJ, King BF, et al. Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials. Journal of the American Society of Nephrology : Jasn. 26: 160-72. PMID 24904092 DOI: 10.1681/ASN.2013101138  1
2015 Leightner A, Harris PC. Meckel syndrome Polycystic Kidney Disease: From Bench to Bedside. 77-89. DOI: 10.2217/EBO.12.263  1
2014 Schrier RW, Abebe KZ, Perrone RD, Torres VE, Braun WE, Steinman TI, Winklhofer FT, Brosnahan G, Czarnecki PG, Hogan MC, Miskulin DC, Rahbari-Oskoui FF, Grantham JJ, Harris PC, Flessner MF, et al. Blood pressure in early autosomal dominant polycystic kidney disease. The New England Journal of Medicine. 371: 2255-66. PMID 25399733 DOI: 10.1056/NEJMoa1402685  1
2014 Torres VE, Abebe KZ, Chapman AB, Schrier RW, Braun WE, Steinman TI, Winklhofer FT, Brosnahan G, Czarnecki PG, Hogan MC, Miskulin DC, Rahbari-Oskoui FF, Grantham JJ, Harris PC, Flessner MF, et al. Angiotensin blockade in late autosomal dominant polycystic kidney disease. The New England Journal of Medicine. 371: 2267-76. PMID 25399731 DOI: 10.1056/NEJMoa1402686  1
2014 Franchi F, Peterson KM, Xu R, Miller B, Psaltis PJ, Harris PC, Lerman LO, Rodriguez-Porcel M. Mesenchymal stromal cells improve renovascular function in Polycystic Kidney Disease. Cell Transplantation. PMID 25290249 DOI: 10.3727/096368914X684619  1
2014 Harris PC, Torres VE. Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease. The Journal of Clinical Investigation. 124: 2315-24. PMID 24892705 DOI: 10.1172/JCI72272  1
2014 Sussman CR, Ward CJ, Leightner AC, Smith JL, Agarwal R, Harris PC, Torres VE. Phosphodiesterase 1A modulates cystogenesis in zebrafish. Journal of the American Society of Nephrology : Jasn. 25: 2222-30. PMID 24700876 DOI: 10.1681/ASN.2013040421  1
2014 Torres VE, Harris PC. Strategies targeting cAMP signaling in the treatment of polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 25: 18-32. PMID 24335972 DOI: 10.1681/ASN.2013040398  1
2014 Paul BM, Consugar MB, Ryan Lee M, Sundsbak JL, Heyer CM, Rossetti S, Kubly VJ, Hopp K, Torres VE, Coto E, Clementi M, Bogdanova N, de Almeida E, Bichet DG, Harris PC. Evidence of a third ADPKD locus is not supported by re-analysis of designated PKD3 families. Kidney International. 85: 383-92. PMID 23760289 DOI: 10.1038/ki.2013.227  1
2013 Wei Q, Xu Q, Zhang Y, Li Y, Zhang Q, Hu Z, Harris PC, Torres VE, Ling K, Hu J. Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes. Nature Communications. 4: 2750. PMID 24231678 DOI: 10.1038/ncomms3750  0.44
2013 Vazifehmand R, Rossetti S, Saber S, Khorshid HR, Harris PC. Molecular analysis of a consanguineous Iranian polycystic kidney disease family identifies a PKD2 mutation that aids diagnostics. Bmc Nephrology. 14: 190. PMID 24011172 DOI: 10.1186/1471-2369-14-190  1
2013 Freedman BS, Lam AQ, Sundsbak JL, Iatrino R, Su X, Koon SJ, Wu M, Daheron L, Harris PC, Zhou J, Bonventre JV. Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations. Journal of the American Society of Nephrology : Jasn. 24: 1571-86. PMID 24009235 DOI: 10.1681/ASN.2012111089  1
2013 Peterson KM, Franchi F, Loeffler DL, Psaltis PJ, Harris PC, Lerman LO, Lerman A, Rodriguez-Porcel M. Endothelial dysfunction occurs prior to clinical evidence of polycystic kidney disease. American Journal of Nephrology. 38: 233-40. PMID 24008943 DOI: 10.1159/000354236  1
2013 Rossetti S, Harris PC. The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD). Current Hypertension Reviews. 9: 37-43. PMID 23971643  1
2013 Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, ... ... Harris PC, et al. ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nature Genetics. 45: 951-6. PMID 23793029 DOI: 10.1038/ng.2681  1
2013 Harris PC, Hopp K. The mutation, a key determinant of phenotype in ADPKD. Journal of the American Society of Nephrology : Jasn. 24: 868-70. PMID 23687354 DOI: 10.1681/ASN.2013040417  1
2013 Leightner AC, Hommerding CJ, Peng Y, Salisbury JL, Gainullin VG, Czarnecki PG, Sussman CR, Harris PC. The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity. Human Molecular Genetics. 22: 2024-40. PMID 23393159 DOI: 10.1093/hmg/ddt054  1
2013 Paavola J, Schliffke S, Rossetti S, Kuo IY, Yuan S, Sun Z, Harris PC, Torres VE, Ehrlich BE. Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 58: 199-208. PMID 23376035 DOI: 10.1016/j.yjmcc.2013.01.015  1
2013 Xu R, Franchi F, Miller B, Crane JA, Peterson KM, Psaltis PJ, Harris PC, Lerman LO, Rodriguez-Porcel M. Polycystic kidneys have decreased vascular density: a micro-CT study. Microcirculation (New York, N.Y. : 1994). 20: 183-9. PMID 23167921 DOI: 10.1111/micc.12022  1
2012 Hopp K, Ward CJ, Hommerding CJ, Nasr SH, Tuan HF, Gainullin VG, Rossetti S, Torres VE, Harris PC. Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity. The Journal of Clinical Investigation. 122: 4257-73. PMID 23064367 DOI: 10.1172/JCI64313  1
2012 Wang X, Ye H, Ward CJ, Chu JY, Masyuk TV, Larusso NF, Harris PC, Chow BK, Torres VE. Insignificant effect of secretin in rodent models of polycystic kidney and liver disease. American Journal of Physiology. Renal Physiology. 303: F1089-98. PMID 22811488 DOI: 10.1152/ajprenal.00242.2012  1
2012 Rossetti S, Hopp K, Sikkink RA, Sundsbak JL, Lee YK, Kubly V, Eckloff BW, Ward CJ, Winearls CG, Torres VE, Harris PC. Identification of gene mutations in autosomal dominant polycystic kidney disease through targeted resequencing. Journal of the American Society of Nephrology : Jasn. 23: 915-33. PMID 22383692 DOI: 10.1681/ASN.2011101032  1
2012 Chapman AB, Bost JE, Torres VE, Guay-Woodford L, Bae KT, Landsittel D, Li J, King BF, Martin D, Wetzel LH, Lockhart ME, Harris PC, Moxey-Mims M, Flessner M, Bennett WM, et al. Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease. Clinical Journal of the American Society of Nephrology : Cjasn. 7: 479-86. PMID 22344503 DOI: 10.2215/CJN.09500911  1
2012 Torres VE, Harris PC. Polycystic kidney disease in 2011: Connecting the dots toward a polycystic kidney disease therapy. Nature Reviews. Nephrology. 8: 66-8. PMID 22158473 DOI: 10.1038/nrneph.2011.196  1
2011 Thatava T, Armstrong AS, De Lamo JG, Edukulla R, Khan YK, Sakuma T, Ohmine S, Sundsbak JL, Harris PC, Kudva YC, Ikeda Y. Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation. Stem Cell Research & Therapy. 2: 48. PMID 22142803 DOI: 10.1186/scrt89  1
2011 Bakeberg JL, Tammachote R, Woollard JR, Hogan MC, Tuan HF, Li M, van Deursen JM, Wu Y, Huang BQ, Torres VE, Harris PC, Ward CJ. Epitope-tagged Pkhd1 tracks the processing, secretion, and localization of fibrocystin. Journal of the American Society of Nephrology : Jasn. 22: 2266-77. PMID 22021705 DOI: 10.1681/ASN.2010111173  1
2011 Irazabal MV, Huston J, Kubly V, Rossetti S, Sundsbak JL, Hogan MC, Harris PC, Brown RD, Torres VE. Extended follow-up of unruptured intracranial aneurysms detected by presymptomatic screening in patients with autosomal dominant polycystic kidney disease. Clinical Journal of the American Society of Nephrology : Cjasn. 6: 1274-85. PMID 21551026 DOI: 10.2215/CJN.09731110  0.44
2011 Hopp K, Heyer CM, Hommerding CJ, Henke SA, Sundsbak JL, Patel S, Patel P, Consugar MB, Czarnecki PG, Gliem TJ, Torres VE, Rossetti S, Harris PC. B9D1 is revealed as a novel Meckel syndrome (MKS) gene by targeted exon-enriched next-generation sequencing and deletion analysis. Human Molecular Genetics. 20: 2524-34. PMID 21493627 DOI: 10.1093/hmg/ddr151  1
2011 Hartley JL, O'Callaghan C, Rossetti S, Consugar M, Ward CJ, Kelly DA, Harris PC. Investigation of primary cilia in the pathogenesis of biliary atresia. Journal of Pediatric Gastroenterology and Nutrition. 52: 485-8. PMID 21407107 DOI: 10.1097/MPG.0b013e318200eb6f  1
2011 Ward CJ, Wu Y, Johnson RA, Woollard JR, Bergstralh EJ, Cicek MS, Bakeberg J, Rossetti S, Heyer CM, Petersen GM, Lindor NM, Thibodeau SN, Harris PC, Torres VE, Hogan MC, et al. Germline PKHD1 mutations are protective against colorectal cancer. Human Genetics. 129: 345-9. PMID 21274727 DOI: 10.1007/s00439-011-0950-8  1
2011 Mohney BG, Pulido JS, Lindor NM, Hogan MC, Consugar MB, Peters J, Pankratz VS, Nasr SH, Smith SJ, Gloor J, Kubly V, Spencer D, Nielson R, Puffenberger EG, Strauss KA, ... ... Harris PC, et al. A novel mutation of LAMB2 in a multigenerational mennonite family reveals a new phenotypic variant of Pierson syndrome. Ophthalmology. 118: 1137-44. PMID 21236492 DOI: 10.1016/j.ophtha.2010.10.009  1
2010 Liu M, Shi S, Senthilnathan S, Yu J, Wu E, Bergmann C, Zerres K, Bogdanova N, Coto E, Deltas C, Pierides A, Demetriou K, Devuyst O, Gitomer B, Laakso M, ... ... Harris PC, et al. Genetic variation of DKK3 may modify renal disease severity in ADPKD. Journal of the American Society of Nephrology : Jasn. 21: 1510-20. PMID 20616171 DOI: 10.1681/ASN.2010030237  1
2010 Vujic M, Heyer CM, Ars E, Hopp K, Markoff A, Orndal C, Rudenhed B, Nasr SH, Torres VE, Torra R, Bogdanova N, Harris PC. Incompletely penetrant PKD1 alleles mimic the renal manifestations of ARPKD. Journal of the American Society of Nephrology : Jasn. 21: 1097-102. PMID 20558538 DOI: 10.1681/ASN.2009101070  1
2010 Harris PC. What is the role of somatic mutation in autosomal dominant polycystic kidney disease? Journal of the American Society of Nephrology : Jasn. 21: 1073-6. PMID 20488953 DOI: 10.1681/ASN.2010030328  1
2010 Hogan MC, Masyuk TV, Page LJ, Kubly VJ, Bergstralh EJ, Li X, Kim B, King BF, Glockner J, Holmes DR, Rossetti S, Harris PC, LaRusso NF, Torres VE. Randomized clinical trial of long-acting somatostatin for autosomal dominant polycystic kidney and liver disease. Journal of the American Society of Nephrology : Jasn. 21: 1052-61. PMID 20431041 DOI: 10.1681/ASN.2009121291  1
2010 Harris PC, Rossetti S. Determinants of renal disease variability in ADPKD. Advances in Chronic Kidney Disease. 17: 131-9. PMID 20219616 DOI: 10.1053/j.ackd.2009.12.004  1
2010 Harris PC, Rossetti S. Molecular diagnostics for autosomal dominant polycystic kidney disease. Nature Reviews. Nephrology. 6: 197-206. PMID 20177400 DOI: 10.1038/nrneph.2010.18  1
2010 Kurbegovic A, Côté O, Couillard M, Ward CJ, Harris PC, Trudel M. Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes. Human Molecular Genetics. 19: 1174-89. PMID 20053665 DOI: 10.1093/hmg/ddp588  1
2010 Wang X, Ward CJ, Harris PC, Torres VE. Cyclic nucleotide signaling in polycystic kidney disease. Kidney International. 77: 129-40. PMID 19924104 DOI: 10.1038/ki.2009.438  1
2010 Torres VE, Harris PC. Autosomal Dominant Polycystic Kidney Disease Comprehensive Clinical Nephrology. 529-542. DOI: 10.1016/B978-0-323-05876-6.00044-7  1
2009 Tammachote R, Hommerding CJ, Sinders RM, Miller CA, Czarnecki PG, Leightner AC, Salisbury JL, Ward CJ, Torres VE, Gattone VH, Harris PC. Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3. Human Molecular Genetics. 18: 3311-23. PMID 19515853 DOI: 10.1093/hmg/ddp272  1
2009 Torres VE, Harris PC. Autosomal dominant polycystic kidney disease: the last 3 years. Kidney International. 76: 149-68. PMID 19455193 DOI: 10.1038/ki.2009.128  1
2009 Harris PC. 2008 Homer W. Smith Award: insights into the pathogenesis of polycystic kidney disease from gene discovery. Journal of the American Society of Nephrology : Jasn. 20: 1188-98. PMID 19423684 DOI: 10.1681/ASN.2009010014  1
2009 Streets AJ, Wagner BE, Harris PC, Ward CJ, Ong AC. Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells. Journal of Cell Science. 122: 1410-7. PMID 19351715 DOI: 10.1242/jcs.045021  1
2009 Xu C, Shmukler BE, Nishimura K, Kaczmarek E, Rossetti S, Harris PC, Wandinger-Ness A, Bacallao RL, Alper SL. Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells. American Journal of Physiology. Renal Physiology. 296: F1464-76. PMID 19244404 DOI: 10.1152/ajprenal.90542.2008  1
2009 Rossetti S, Kubly VJ, Consugar MB, Hopp K, Roy S, Horsley SW, Chauveau D, Rees L, Barratt TM, van't Hoff WG, Niaudet P, Niaudet WP, Torres VE, Harris PC. Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease. Kidney International. 75: 848-55. PMID 19165178 DOI: 10.1038/ki.2008.686  1
2009 Hogan MC, Manganelli L, Woollard JR, Masyuk AI, Masyuk TV, Tammachote R, Huang BQ, Leontovich AA, Beito TG, Madden BJ, Charlesworth MC, Torres VE, LaRusso NF, Harris PC, Ward CJ. Characterization of PKD protein-positive exosome-like vesicles. Journal of the American Society of Nephrology : Jasn. 20: 278-88. PMID 19158352 DOI: 10.1681/ASN.2008060564  1
2009 Harris PC, Torres VE. Polycystic kidney disease. Annual Review of Medicine. 60: 321-37. PMID 18947299 DOI: 10.1146/annurev.med.60.101707.125712  1
2009 Wang X, Harris PC, Somlo S, Batlle D, Torres VE. Effect of calcium-sensing receptor activation in models of autosomal recessive or dominant polycystic kidney disease. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 24: 526-34. PMID 18826972 DOI: 10.1093/ndt/gfn527  1
2009 Harris PC, Czarnecki PG. Ciliopathies Medizinische Genetik. 21: 14-20. DOI: 10.1007/s11825-009-0144-0  1
2008 Consugar MB, Wong WC, Lundquist PA, Rossetti S, Kubly VJ, Walker DL, Rangel LJ, Aspinwall R, Niaudet WP, Ozen S, David A, Velinov M, Bergstralh EJ, Bae KT, Chapman AB, ... ... Harris PC, et al. Characterization of large rearrangements in autosomal dominant polycystic kidney disease and the PKD1/TSC2 contiguous gene syndrome. Kidney International. 74: 1468-79. PMID 18818683 DOI: 10.1038/ki.2008.485  1
2008 Aitman TJ, Critser JK, Cuppen E, Dominiczak A, Fernandez-Suarez XM, Flint J, Gauguier D, Geurts AM, Gould M, Harris PC, Holmdahl R, Hubner N, Izsvák Z, Jacob HJ, Kuramoto T, et al. Progress and prospects in rat genetics: a community view. Nature Genetics. 40: 516-22. PMID 18443588 DOI: 10.1038/ng.147  1
2008 Harris PC, Rossetti S. Molecular diagnostics of ADPKD coming of age. Clinical Journal of the American Society of Nephrology : Cjasn. 3: 1-2. PMID 18178778 DOI: 10.2215/CJN.05061107  1
2008 Wang X, Wu Y, Ward CJ, Harris PC, Torres VE. Vasopressin directly regulates cyst growth in polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 19: 102-8. PMID 18032793 DOI: 10.1681/ASN.2007060688  1
2008 Harris PC, Torres VE. Autosomal recessive polycystic kidney disease Molecular and Genetic Basis of Renal Disease. 119-130. DOI: 10.1016/B978-1-4160-0252-9.50011-2  1
2007 Torres VE, Rossetti S, Harris PC. Update on autosomal dominant polycystic kidney disease Minerva Medica. 98: 669-691. PMID 18299682  1
2007 Harris PC. Genetic complexity in Joubert syndrome and related disorders Kidney International. 72: 1421-1423. PMID 18046420 DOI: 10.1038/sj.ki.5002577  1
2007 Yin M, Woollard J, Wang X, Torres VE, Harris PC, Ward CJ, Glaser KJ, Manduca A, Ehman RL. Quantitative assessment of hepatic fibrosis in an animal model with magnetic resonance elastography. Magnetic Resonance in Medicine. 58: 346-53. PMID 17654577 DOI: 10.1002/mrm.21286  1
2007 Rossetti S, Consugar MB, Chapman AB, Torres VE, Guay-Woodford LM, Grantham JJ, Bennett WM, Meyers CM, Walker DL, Bae K, Zhang QJ, Thompson PA, Miller JP, Harris PC. Comprehensive molecular diagnostics in autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 18: 2143-60. PMID 17582161 DOI: 10.1681/ASN.2006121387  1
2007 Monico CG, Rossetti S, Schwanz HA, Olson JB, Lundquist PA, Dawson DB, Harris PC, Milliner DS. Comprehensive mutation screening in 55 probands with type 1 primary hyperoxaluria shows feasibility of a gene-based diagnosis. Journal of the American Society of Nephrology : Jasn. 18: 1905-14. PMID 17460142 DOI: 10.1681/ASN.2006111230  1
2007 Torres VE, Harris PC, Pirson Y. Autosomal dominant polycystic kidney disease. Lancet (London, England). 369: 1287-301. PMID 17434405 DOI: 10.1016/S0140-6736(07)60601-1  1
2007 Rossetti S, Harris PC. Genotype-phenotype correlations in autosomal dominant and autosomal recessive polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 18: 1374-80. PMID 17429049 DOI: 10.1681/ASN.2007010125  1
2007 Gout AM, Ravine D, Harris PC, Rossetti S, Peters D, Breuning M, Henske EP, Koizumi A, Inoue S, Shimizu Y, Thongnoppakhun W, Yenchitsomanus PT, Deltas C, Sandford R, et al. Analysis of published PKD1 gene sequence variants. Nature Genetics. 39: 427-8. PMID 17392796 DOI: 10.1038/ng0407-427  1
2007 Masyuk TV, Masyuk AI, Torres VE, Harris PC, Larusso NF. Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate. Gastroenterology. 132: 1104-16. PMID 17383431 DOI: 10.1053/j.gastro.2006.12.039  1
2007 Consugar MB, Kubly VJ, Lager DJ, Hommerding CJ, Wong WC, Bakker E, Gattone VH, Torres VE, Breuning MH, Harris PC. Molecular diagnostics of Meckel-Gruber syndrome highlights phenotypic differences between MKS1 and MKS3. Human Genetics. 121: 591-9. PMID 17377820 DOI: 10.1007/s00439-007-0341-3  1
2007 Torres VE, Harris PC. Polycystic kidney disease: Genes, proteins, animal models, disease mechanisms and therapeutic opportunities Journal of Internal Medicine. 261: 17-31. PMID 17222165 DOI: 10.1111/j.1365-2796.2006.01743.x  1
2006 Harris PC. Genetic studies: a key to understanding pathogenesis in PKD. Nephrology News & Issues. 20: 20-2. PMID 17168054  1
2006 Xu N, Glockner JF, Rossetti S, Babovich-Vuksanovic D, Harris PC, Torres VE. Autosomal dominant polycystic kidney disease coexisting with cystic fibrosis. Journal of Nephrology. 19: 529-34. PMID 17048214  1
2006 Harris PC, Bae KT, Rossetti S, Torres VE, Grantham JJ, Chapman AB, Guay-Woodford LM, King BF, Wetzel LH, Baumgarten DA, Kenney PJ, Consugar M, Klahr S, Bennett WM, Meyers CM, et al. Cyst number but not the rate of cystic growth is associated with the mutated gene in autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 17: 3013-9. PMID 17035604 DOI: 10.1681/ASN.2006080835  1
2006 Hiesberger T, Gourley E, Erickson A, Koulen P, Ward CJ, Masyuk TV, Larusso NF, Harris PC, Igarashi P. Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C. The Journal of Biological Chemistry. 281: 34357-64. PMID 16956880 DOI: 10.1074/jbc.M606740200  1
2006 Torres VE, Harris PC. Mechanisms of Disease: autosomal dominant and recessive polycystic kidney diseases. Nature Clinical Practice. Nephrology. 2: 40-55; quiz 55. PMID 16932388 DOI: 10.1038/ncpneph0070  1
2006 Sutton KA, Jungnickel MK, Ward CJ, Harris PC, Florman HM. Functional characterization of PKDREJ, a male germ cell-restricted polycystin. Journal of Cellular Physiology. 209: 493-500. PMID 16883570 DOI: 10.1002/jcp.20755  1
2006 Harris PC, Torres VE. Understanding pathogenic mechanisms in polycystic kidney disease provides clues for therapy. Current Opinion in Nephrology and Hypertension. 15: 456-63. PMID 16775462 DOI: 10.1097/01.mnh.0000232888.65895.e7  1
2006 Grantham JJ, Torres VE, Chapman AB, Guay-Woodford LM, Bae KT, King BF, Wetzel LH, Baumgarten DA, Kenney PJ, Harris PC, Klahr S, Bennett WM, Hirschman GN, Meyers CM, Zhang X, et al. Volume progression in polycystic kidney disease. The New England Journal of Medicine. 354: 2122-30. PMID 16707749 DOI: 10.1056/NEJMoa054341  1
2006 Nauli SM, Rossetti S, Kolb RJ, Alenghat FJ, Consugar MB, Harris PC, Ingber DE, Loghman-Adham M, Zhou J. Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. Journal of the American Society of Nephrology : Jasn. 17: 1015-25. PMID 16565258 DOI: 10.1681/ASN.2005080830  1
2006 Woerner AC, Au KS, Williams AT, Harris PC, Northrup H. Tuberous sclerosis complex and polycystic kidney disease together: an exception to the contiguous gene syndrome. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 8: 197-8. PMID 16540757 DOI: 10.1097/01.gim.0000204466.34876.d5  1
2006 Adeva M, El-Youssef M, Rossetti S, Kamath PS, Kubly V, Consugar MB, Milliner DM, King BF, Torres VE, Harris PC. Clinical and molecular characterization defines a broadened spectrum of autosomal recessive polycystic kidney disease (ARPKD). Medicine. 85: 1-21. PMID 16523049 DOI: 10.1097/01.md.0000200165.90373.9a  1
2006 Smith UM, Consugar M, Tee LJ, McKee BM, Maina EN, Whelan S, Morgan NV, Goranson E, Gissen P, Lilliquist S, Aligianis IA, Ward CJ, Pasha S, Punyashthiti R, Malik Sharif S, ... ... Harris PC, et al. The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat. Nature Genetics. 38: 191-6. PMID 16415887 DOI: 10.1038/ng1713  1
2005 Kip SN, Hunter LW, Ren Q, Harris PC, Somlo S, Torres VE, Sieck GC, Qian Q. [Ca2+]i reduction increases cellular proliferation and apoptosis in vascular smooth muscle cells: relevance to the ADPKD phenotype. Circulation Research. 96: 873-80. PMID 15790956 DOI: 10.1161/01.RES.0000163278.68142.8a  1
2005 Ong AC, Harris PC. Molecular pathogenesis of ADPKD: the polycystin complex gets complex. Kidney International. 67: 1234-47. PMID 15780076 DOI: 10.1111/j.1523-1755.2005.00201.x  1
2005 Wang X, Gattone V, Harris PC, Torres VE. Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat. Journal of the American Society of Nephrology : Jasn. 16: 846-51. PMID 15728778 DOI: 10.1681/ASN.2004121090  1
2005 Consugar MB, Anderson SA, Rossetti S, Pankratz VS, Ward CJ, Torra R, Coto E, El-Youssef M, Kantarci S, Utsch B, Hildebrandt F, Sweeney WE, Avner ED, Torres VE, Cunningham JM, ... Harris PC, et al. Haplotype analysis improves molecular diagnostics of autosomal recessive polycystic kidney disease. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 45: 77-87. PMID 15696446 DOI: 10.1053/j.ajkd.2004.09.009  1
2004 Masyuk TV, Huang BQ, Masyuk AI, Ritman EL, Torres VE, Wang X, Harris PC, Larusso NF. Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease. The American Journal of Pathology. 165: 1719-30. PMID 15509540 DOI: 10.1016/S0002-9440(10)63427-X  0.44
2004 Torres VE, Sweeney WE, Wang X, Qian Q, Harris PC, Frost P, Avner ED. Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats. Kidney International. 66: 1766-73. PMID 15496147 DOI: 10.1111/j.1523-1755.2004.00952.x  0.44
2004 Gibbs GF, Huston J, Qian Q, Kubly V, Harris PC, Brown RD, Torres VE. Follow-up of intracranial aneurysms in autosomal-dominant polycystic kidney disease. Kidney International. 65: 1621-7. PMID 15086900 DOI: 10.1111/j.1523-1755.2004.00572.x  0.44
2004 Aguiari G, Banzi M, Gessi S, Cai Y, Zeggio E, Manzati E, Piva R, Lambertini E, Ferrari L, Peters DJ, Lanza F, Harris PC, Borea PA, Somlo S, Del Senno L. Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 884-6. PMID 15001556 DOI: 10.1096/fj.03-0687fje  1
2004 Torres VE, Wang X, Qian Q, Somlo S, Harris PC, Gattone VH. Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease. Nature Medicine. 10: 363-4. PMID 14991049 DOI: 10.1038/nm1004  1
2004 Harris PC, Rossetti S. Molecular genetics of autosomal recessive polycystic kidney disease. Molecular Genetics and Metabolism. 81: 75-85. PMID 14741187 DOI: 10.1016/j.ymgme.2003.10.010  1
2004 Roitbak T, Ward CJ, Harris PC, Bacallao R, Ness SA, Wandinger-Ness A. A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells. Molecular Biology of the Cell. 15: 1334-46. PMID 14718571 DOI: 10.1091/mbc.E03-05-0296  1
2003 Masyuk TV, Huang BQ, Ward CJ, Masyuk AI, Yuan D, Splinter PL, Punyashthiti R, Ritman EL, Torres VE, Harris PC, LaRusso NF. Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat. Gastroenterology. 125: 1303-10. PMID 14598246 DOI: 10.1016/j.gastro.2003.09.001  1
2003 Torres VE, Sweeney WE, Wang X, Qian Q, Harris PC, Frost P, Avner ED. EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats. Kidney International. 64: 1573-9. PMID 14531789 DOI: 10.1046/j.1523-1755.2003.00256.x  0.44
2003 Gattone VH, Wang X, Harris PC, Torres VE. Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist. Nature Medicine. 9: 1323-6. PMID 14502283 DOI: 10.1038/nm935  1
2003 Qian Q, Li M, Cai Y, Ward CJ, Somlo S, Harris PC, Torres VE. Analysis of the polycystins in aortic vascular smooth muscle cells. Journal of the American Society of Nephrology : Jasn. 14: 2280-7. PMID 12937304 DOI: 10.1097/01.ASN.0000080185.38113.A3  1
2003 Hogan MC, Griffin MD, Rossetti S, Torres VE, Ward CJ, Harris PC. PKHDL1, a homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor with inducible T lymphocyte expression Human Molecular Genetics. 12: 685-698. PMID 12620974 DOI: 10.1093/hmg/12.6.685  1
2003 Walker D, Consugar M, Slezak J, Rossetti S, Torres VE, Winearls CG, Harris PC. The ENOS polymorphism is not associated with severity of renal disease in polycystic kidney disease 1 American Journal of Kidney Diseases. 41: 90-94. PMID 12500225 DOI: 10.1053/ajkd.2003.50027  1
2002 Harris PC. Molecular basis of polycystic kidney disease: PKD1, PKD2 and PKHD1 Current Opinion in Nephrology and Hypertension. 11: 309-314. PMID 11981261 DOI: 10.1097/00041552-200205000-00007  1
2002 Newby LJ, Streets AJ, Zhao Y, Harris PC, Ward CJ, Ong ACM. Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex Journal of Biological Chemistry. 277: 20763-20773. PMID 11901144 DOI: 10.1074/jbc.M107788200  1
2001 Qian Q, Harris PC, Torres VE. Treatment prospects for autosomal-dominant polycystic kidney disease Kidney International. 59: 2005-2022. PMID 11380803 DOI: 10.1046/j.1523-1755.2001.0590062005.x  1
2000 Koptides M, Mean R, Demetriou K, Constantinides R, Pierides A, Harris PC, Deltas CC. Screening of the PKD1 duplicated region reveals multiple single nucleotide polymorphisms and a de novo mutation in Hellenic polycystic kidney disease families Human Mutation. 16: 176. PMID 10923040  1
1999 Harris PC. Autosomal dominant polycystic kidney disease: Clues to pathogenesis Human Molecular Genetics. 8: 1861-1866. PMID 10469838 DOI: 10.1093/hmg/8.10.1861  1
1999 Hughes J, Ward CJ, Aspinwall R, Butler R, Harris PC. Identification of a human homologue of the sea urchin receptor for egg jelly: A polycystic kidney disease-like protein Human Molecular Genetics. 8: 543-549. PMID 9949214  1
1998 Torra R, Badenas C, Darnell A, Camacho JA, Aspinwall R, Harris PC, Estivill X. Facilitated diagnosis of the contiguous gene syndrome: tuberous sclerosis and polycystic kidneys by means of haplotype studies. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 31: 1038-43. PMID 9631851  1
1997 Harris PC. The TSC2/PKD1 contiguous gene syndrome Contributions to Nephrology. 122: 76-82. PMID 9399043  1
1997 Maheshwar MM, Cheadle JP, Jones AC, Myring J, Fryer AE, Harris PC, Sampson JR. The GAP-related domain of tuberin, the product of the TSC2 gene, is a target for missense mutations in tuberous sclerosis. Human Molecular Genetics. 6: 1991-6. PMID 9302281 DOI: 10.1093/hmg/6.11.1991  1
1997 Harris PC, Watson ML. Autosomal dominant polycystic kidney disease: neoplasia in disguise? Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 12: 1089-90. PMID 9198029 DOI: 10.1093/ndt/12.6.1089  1
1997 Ong ACM, Harris PC. Molecular basis of renal cyst formation - One hit two? Lancet. 349: 1039-1040. PMID 9107237 DOI: 10.1016/S0140-6736(05)62286-6  1
1997 Harris PC. Autosomal dominant polycystic kidney disease: A genetic perspective Nephrology. 3: 387-395.  1
1996 Peral B, Ong ACM, San Millán JL, Gamble V, Rees L, Harris PC. A stable, nonsense mutation associated with a case of infantile onset polycystic kidney disease 1 (PKD1) Human Molecular Genetics. 5: 539-542. PMID 8845849 DOI: 10.1093/hmg/5.4.539  1
1996 Harris PC. Identification of a gene for autosomal dominant polycystic kidney disease: Implications for understanding the pathogenesis and treatment of the disease Nephrology Dialysis Transplantation. 11: 258-262. PMID 8700362  1
1996 Olsson PG, Lohning C, Horsley S, Kearney L, Harris PC, Frischauf AM. The mouse homologue of the polycystic kidney disease gene (Pkd1) is a single-copy gene Genomics. 34: 233-235. PMID 8661056 DOI: 10.1006/geno.1996.0273  1
1995 Harris PC, Ward CJ, Peral B, Hughes J. Polycystic kidney disease 1: Identification and analysis of the primary defect Journal of the American Society of Nephrology. 6: 1125-1133. PMID 8589278  1
1995 Harris PC. Molecular genetics of ADPKD Contributions to Nephrology. 115: 8-15. PMID 8585923  1
1995 Harris PC, Ward CJ, Peral B, Hughes J. Autosomal dominant polycystic kidney disease: Molecular analysis Human Molecular Genetics. 4: 1745-1749. PMID 8541874  1
1995 Harris PC, Germino G, Klinger K, Landes G, Van Adelsberg J. The PKD1 gene product Nature Medicine. 1: 493. PMID 7585106 DOI: 10.1038/nm0695-493a  1
1994 Sampson JR, Harris PC. The molecular genetics of tuberous sclerosis Human Molecular Genetics. 3: 1477-1480. PMID 7849741  1
1993 Vickers MA, Vyas P, Harris PC, Simmons DL, Higgs DR. Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere Proceedings of the National Academy of Sciences of the United States of America. 90: 3437-3441. PMID 8475094  1
1993 Armour JAL, Harris PC, Jeffreys AJ. Allelic diversity at minisatellite MS205 (D16S309): Evidence for polarized variability Human Molecular Genetics. 2: 1137-1145. PMID 8401495 DOI: 10.1093/hmg/2.8.1137  1
1991 Harris PC, Thomas S, Ratcliffe PJ, Breuning MH, Coto E, Lopez-Larrea C. Rapid genetic analysis of families with polycystic kidney disease 1 by means of a microsatellite marker The Lancet. 338: 1484-1487. PMID 1683919 DOI: 10.1016/0140-6736(91)92300-Q  1
1990 Harris PC, Barton NJ, Higgs DR, Reeders ST, Wilkie AOM. A long-range restriction map between the α-globin complex and a marker closely linked to the polycystic kidney disease 1 (PKD1) locus Genomics. 7: 195-206. PMID 2347584 DOI: 10.1016/0888-7543(90)90541-2  1
1990 Wilkie AOM, Lamb J, Harris PC, Finney RD, Higgs DR. A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n Nature. 346: 868-871. PMID 1975428  1
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