Hanna Mikkola - Publications

Affiliations: 
Molecular Biology 0573 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Cell Biology, Medicine and Surgery

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Calvanese V, Mikkola H. The genesis of human hematopoietic stem cells. Blood. PMID 37339578 DOI: 10.1182/blood.2022017934  0.529
2022 Calvanese V, Capellera-Garcia S, Ma F, Fares I, Liebscher S, Ng ES, Ekstrand S, Aguadé-Gorgorió J, Vavilina A, Lefaudeux D, Nadel B, Li JY, Wang Y, Lee LK, Ardehali R, ... ... Mikkola HKA, et al. Mapping human haematopoietic stem cells from haemogenic endothelium to birth. Nature. 604: 534-540. PMID 35418685 DOI: 10.1038/s41586-022-04571-x  0.694
2020 Fang S, Chen S, Nurmi H, Leppänen VM, Jeltsch M, Scadden DT, Silberstein L, Mikkola H, Alitalo K. VEGF-C Protects the Integrity of Bone Marrow Perivascular Niche. Blood. PMID 32842144 DOI: 10.1182/Blood.2020005699  0.495
2019 Calvanese V, Nguyen AT, Bolan TJ, Vavilina A, Su T, Lee LK, Wang Y, Lay FD, Magnusson M, Crooks GM, Kurdistani SK, Mikkola HKA. MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment. Nature. PMID 31776511 DOI: 10.1038/S41586-019-1790-2  0.649
2018 Ferguson GB, Van Handel B, Bay M, Fiziev P, Org T, Lee S, Shkhyan R, Banks NW, Scheinberg M, Wu L, Saitta B, Elphingstone J, Larson AN, Riester SM, Pyle AD, ... ... Mikkola HK, et al. Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes. Nature Communications. 9: 3634. PMID 30194383 DOI: 10.1038/S41467-018-05573-Y  0.759
2018 Grace CS, Mikkola HKA, Dou DR, Calvanese V, Ronn RE, Purton LE. Protagonist or antagonist? The complex roles of retinoids in the regulation of hematopoietic stem cells and their specification from pluripotent stem cells. Experimental Hematology. PMID 29981365 DOI: 10.1016/j.exphem.2018.06.287  0.509
2018 Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, ... Mikkola HKA, et al. Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nature Communications. 9: 754. PMID 29467410 DOI: 10.1038/S41467-018-02891-Z  0.35
2018 Lay F, Oh H, Duan D, Org T, Israely E, Mikkola H. Distinct and Overlapping Function for Scl, Lmo2 and Ldb1 in Regulating the Divergence of Hematopoietic and Cardiac Fates Experimental Hematology. 64. DOI: 10.1016/J.Exphem.2018.06.270  0.343
2018 Ghorbanian Y, Lee L, Mikkola H, Inlay M. Lyve1-Derived Hematopoietic Stem Cells are Intrinsically Different in Their Lineage Output Than Other HSCs Experimental Hematology. 64: S67. DOI: 10.1016/J.Exphem.2018.06.230  0.712
2017 Komorowska K, Doyle A, Wahlestedt M, Subramaniam A, Debnath S, Chen J, Soneji S, Van Handel B, Mikkola HKA, Miharada K, Bryder D, Larsson J, Magnusson M. Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration. Cell Reports. 21: 3514-3523. PMID 29262330 DOI: 10.1016/J.Celrep.2017.11.084  0.784
2017 Ghorbanian Y, Lee L, Mikkola H, Inlay M. Tracing the emergence of hematopoietic stem cells from the extra-embryonic yolk sac Experimental Hematology. 53: S104. DOI: 10.1016/J.Exphem.2017.06.252  0.723
2017 Calvanese V, Nguyen AT, Bolan T, Galic Z, Mikkola H. MLLT3 sustains human HSC self-renewal and engraftment Experimental Hematology. 53. DOI: 10.1016/J.Exphem.2017.06.046  0.315
2017 Elefanty A, Ng E, Bruveris F, Azzola L, Phipson B, Vlahos K, Leuitoguinho AR, Calvanese V, Schenke-Layland K, Oshlack A, Mikkola H, Stanley E. Modeling human hematopoiesis in pluripotent stem cells Experimental Hematology. 53. DOI: 10.1016/J.Exphem.2017.06.021  0.539
2016 Lee LK, Ghorbanian Y, Wang W, Wang Y, Kim YJ, Weissman IL, Inlay MA, Mikkola HK. LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage. Cell Reports. 17: 2286-2298. PMID 27880904 DOI: 10.1016/J.Celrep.2016.10.080  0.674
2016 Ng ES, Azzola L, Bruveris FF, Calvanese V, Phipson B, Vlahos K, Hirst C, Jokubaitis VJ, Yu QC, Maksimovic J, Liebscher S, Januar V, Zhang Z, Williams B, Conscience A, ... ... Mikkola HK, et al. Differentiation of human embryonic stem cells to HOXA(+) hemogenic vasculature that resembles the aorta-gonad-mesonephros. Nature Biotechnology. PMID 27748754 DOI: 10.1038/Nbt.3702  0.503
2016 Fang S, Nurmi H, Heinolainen K, Chen S, Salminen E, Saharinen P, Mikkola HK, Alitalo K. Critical requirement of VEGF-C in transition to fetal erythropoiesis. Blood. PMID 27343251 DOI: 10.1182/Blood-2015-12-687970  0.319
2016 Dou DR, Calvanese V, Sierra MI, Nguyen AT, Minasian A, Saarikoski P, Sasidharan R, Ramirez CM, Zack JA, Crooks GM, Galic Z, Mikkola HK. Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Nature Cell Biology. PMID 27183470 DOI: 10.1038/Ncb3354  0.486
2016 Calvanese V, Mikkola HK. Tracking HSC Origin: From Bench to Placenta. Developmental Cell. 36: 479-80. PMID 26954540 DOI: 10.1016/j.devcel.2016.02.022  0.42
2016 Mikkola H, Dou D, Calvanese V, Saarikoski P, Galic Z. Induction of HOXA genes in hESC-derived HSPC by two-step differentiation and RA signalling pulse Protocol Exchange. DOI: 10.1038/Protex.2016.035  0.316
2016 Inlay M, Ghorbanian Y, Lee L, Mikkola H. Lyve1 marks yolk sac derived hematopoietic stem cells and nearly half of adult blood Experimental Hematology. 44: S32. DOI: 10.1016/J.Exphem.2016.06.025  0.682
2016 Mikkola H, Calvanese V, Dou D. Mechanisms regulating hematopoietic stem cell fate during human development Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.017  0.583
2015 Sadarangani A, Pineda G, Lennon KM, Chun HJ, Shih A, Schairer AE, Court AC, Goff DJ, Prashad SL, Geron I, Wall R, McPherson JD, Moore RA, Pu M, Bao L, ... ... Mikkola HK, et al. GLI2 inhibition abrogates human leukemia stem cell dormancy. Journal of Translational Medicine. 13: 98. PMID 25889765 DOI: 10.1186/S12967-015-0453-9  0.503
2015 Org T, Duan D, Ferrari R, Montel-Hagen A, Van Handel B, Kerényi MA, Sasidharan R, Rubbi L, Fujiwara Y, Pellegrini M, Orkin SH, Kurdistani SK, Mikkola HK. Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence. The Embo Journal. 34: 759-77. PMID 25564442 DOI: 10.15252/Embj.201490542  0.727
2015 Prashad SL, Calvanese V, Yao CY, Kaiser J, Wang Y, Sasidharan R, Crooks G, Magnusson M, Mikkola HK. GPI-80 defines self-renewal ability in hematopoietic stem cells during human development. Cell Stem Cell. 16: 80-7. PMID 25465114 DOI: 10.1016/j.stem.2014.10.020  0.454
2015 Lee L, Ghorbanian Y, Weissman I, Inlay M, Mikkola H. Lyve1 marks yolk sac definitive hemogenic endothelium Experimental Hematology. 43: S80. DOI: 10.1016/J.Exphem.2015.06.195  0.524
2015 Komorowska K, Doyle A, Soneji S, Hultmark S, Bryder D, Mikkola H, Larsson J, Magnusson M. Hepatic leukemia factor is essential for maintaining hematopoietic stem cell function Experimental Hematology. 43: S73. DOI: 10.1016/J.Exphem.2015.06.166  0.53
2015 Dou DR, Calvanese V, Sierra MI, Sasidharan R, Zack JA, Crooks GM, Galic Z, Mikkola H. Medial HOXA gene expression is required for establishing “stemness” in human HSCs Experimental Hematology. 43: S48. DOI: 10.1016/J.Exphem.2015.06.064  0.337
2014 Mishra BP, Zaffuto KM, Artinger EL, Org T, Mikkola HK, Cheng C, Djabali M, Ernst P. The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis. Cell Reports. 7: 1239-47. PMID 24813891 DOI: 10.1016/J.Exphem.2014.07.061  0.353
2014 Calvanese V, Lee LK, Mikkola HK. Sex hormone drives blood stem cell reproduction. The Embo Journal. 33: 534-5. PMID 24562387 DOI: 10.1002/Embj.201487976  0.654
2014 Calvanese V, Prashad S, Magnusson M, Sierra M, Mikkola H. GPI-80+ human fetal hematopoietic stem cells uncover novel regulators of stemness Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.094  0.58
2013 Ueno M, Lee LK, Chhabra A, Kim YJ, Sasidharan R, Van Handel B, Wang Y, Kamata M, Kamran P, Sereti KI, Ardehali R, Jiang M, Mikkola HK. c-Met-dependent multipotent labyrinth trophoblast progenitors establish placental exchange interface. Developmental Cell. 27: 373-86. PMID 24286824 DOI: 10.1016/J.Devcel.2013.10.019  0.813
2013 Oh P, Lobry C, Gao J, Tikhonova A, Loizou E, Manent J, Manet J, van Handel B, Ibrahim S, Greve J, Mikkola H, Artavanis-Tsakonas S, Aifantis I. In vivo mapping of notch pathway activity in normal and stress hematopoiesis. Cell Stem Cell. 13: 190-204. PMID 23791481 DOI: 10.1016/J.Stem.2013.07.009  0.748
2013 Montel-Hagen A, Van Handel B, Mikkola H. [An unexpected repressive role for Scl in the embryonic endothelium]. Mã©Decine Sciences : M/S. 29: 257-9. PMID 23544378 DOI: 10.1051/Medsci/2013293010  0.724
2013 Nakano H, Liu X, Arshi A, Nakashima Y, van Handel B, Sasidharan R, Harmon AW, Shin JH, Schwartz RJ, Conway SJ, Harvey RP, Pashmforoush M, Mikkola HK, Nakano A. Haemogenic endocardium contributes to transient definitive haematopoiesis. Nature Communications. 4: 1564. PMID 23463007 DOI: 10.1038/Ncomms2569  0.771
2013 Magnusson M, Sierra MI, Sasidharan R, Prashad SL, Romero M, Saarikoski P, Van Handel B, Huang A, Li X, Mikkola HK. Expansion on stromal cells preserves the undifferentiated state of human hematopoietic stem cells despite compromised reconstitution ability. Plos One. 8: e53912. PMID 23342037 DOI: 10.1371/Journal.Pone.0053912  0.775
2013 Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B. Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. Journal of Virology. 87: 2094-108. PMID 23192877 DOI: 10.1128/Jvi.02032-12  0.732
2013 Duan D, Org T, Ferrari R, Montel-Hagen A, van Handel B, Sasidharan R, Fujiwara Y, Orkin S, Kurdistani S, Mikkola H. Scl represses cardiogenesis via distant enhancers during hemogenic endothelium specification Experimental Hematology. 41: S16. DOI: 10.1016/J.Exphem.2013.05.062  0.305
2013 Mikkola H. Uncovering the roadmap to hematopoietic stem cells Experimental Hematology. 41. DOI: 10.1016/J.Exphem.2013.05.038  0.575
2012 Nsair A, Schenke-Layland K, Van Handel B, Evseenko D, Kahn M, Zhao P, Mendelis J, Heydarkhan S, Awaji O, Vottler M, Geist S, Chyu J, Gago-Lopez N, Crooks GM, Plath K, ... ... Mikkola HK, et al. Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. Plos One. 7: e45603. PMID 23056209 DOI: 10.1371/Journal.Pone.0045603  0.792
2012 Xu J, Shao Z, Glass K, Bauer DE, Pinello L, Van Handel B, Hou S, Stamatoyannopoulos JA, Mikkola HK, Yuan GC, Orkin SH. Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis. Developmental Cell. 23: 796-811. PMID 23041383 DOI: 10.1016/J.Devcel.2012.09.003  0.686
2012 Van Handel B, Montel-Hagen A, Sasidharan R, Nakano H, Ferrari R, Boogerd CJ, Schredelseker J, Wang Y, Hunter S, Org T, Zhou J, Li X, Pellegrini M, Chen JN, Orkin SH, ... ... Mikkola HK, et al. Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium. Cell. 150: 590-605. PMID 22863011 DOI: 10.1016/J.Cell.2012.06.026  0.787
2012 Chhabra A, Lechner AJ, Ueno M, Acharya A, Van Handel B, Wang Y, Iruela-Arispe ML, Tallquist MD, Mikkola HK. Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling. Developmental Cell. 22: 651-9. PMID 22387002 DOI: 10.1016/J.Devcel.2011.12.022  0.793
2012 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM. CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. Plos One. 7: e30562. PMID 22363445 DOI: 10.1371/Journal.Pone.0030562  0.716
2012 Hong C, Kidani Y, A-Gonzalez N, Phung T, Ito A, Rong X, Ericson K, Mikkola H, Beaven SW, Miller LS, Shao WH, Cohen PL, Castrillo A, Tontonoz P, Bensinger SJ. Coordinate regulation of neutrophil homeostasis by liver X receptors in mice. The Journal of Clinical Investigation. 122: 337-47. PMID 22156197 DOI: 10.1172/Jci58393  0.312
2012 Patterson M, Chan DN, Ha I, Case D, Cui Y, Van Handel B, Mikkola HK, Lowry WE. Defining the nature of human pluripotent stem cell progeny. Cell Research. 22: 178-93. PMID 21844894 DOI: 10.1038/cr.2011.133  0.511
2012 Nsair A, Schenke-Layland K, Van Handel B, Evseenko D, Kahn M, Zhao P, Mendelis J, Heydarkhan S, Awaji O, Vottler M, Geist S, Chyu J, Gago-Lopez N, Crooks GM, Plath K, ... ... Mikkola HKA, et al. Correction: Characterization and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells Plos One. 7. DOI: 10.1371/annotation/649fb8ef-a4c7-4ee7-b382-e1657b9aa07e  0.788
2012 Org T, Duan D, Montel-Hagen A, Ferrari R, Van Handel B, Sasidharan R, Orkin SH, Kurdistani S, Mikkola H. Scl/Tal1 Directly Activates Hematopoiesis and Represses Cardiogenesis During Mesodermal Diversification Blood. 120: 3446-3446. DOI: 10.1182/Blood.V120.21.3446.3446  0.478
2011 Chhabra A, Mikkola HK. Return to youth with Sox17. Genes & Development. 25: 1557-62. PMID 21828265 DOI: 10.1101/gad.17328611  0.641
2011 Schenke-Layland K, Nsair A, Van Handel B, Angelis E, Gluck JM, Votteler M, Goldhaber JI, Mikkola HK, Kahn M, Maclellan WR. Recapitulation of the embryonic cardiovascular progenitor cell niche. Biomaterials. 32: 2748-56. PMID 21257198 DOI: 10.1016/J.Biomaterials.2010.12.046  0.756
2011 Huang X, Gschweng E, Van Handel B, Cheng D, Mikkola HK, Witte ON. Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells. Blood. 117: 2157-65. PMID 21163928 DOI: 10.1182/Blood-2010-08-302711  0.689
2011 Shih AY, Schairer A, Barrett CL, Geron I, Recart ACC, Goff D, Prashad S, Wu J, Jiang Q, Gotlib J, Balaian L, Minden MD, Leu H, Wall R, Ma W, ... ... Mikkola H, et al. Cycling Toward Leukemia Stem Cell Elimination Wtih a Selective Sonic Hedgehog Antagonist, Blood. 118: 3776-3776. DOI: 10.1182/Blood.V118.21.3776.3776  0.537
2011 Montel-Hagen A, Handel BV, Ferrari R, Sasidharan R, Org T, Boogerd K, Nakano H, Zhou J, Li X, Pellegrini M, Orkin SH, Nakano A, Kurdistani S, Evans S, Mikkola H. Latent Cardiogenic Potential in Endocardium and Hemogenic Endothelium Revealed in the Absence of Scl/tal1 Blood. 118: 2362-2362. DOI: 10.1182/Blood.V118.21.2362.2362  0.523
2011 Maroz A, Van Handel B, Mikkola H, Schoenning J, Reinhardt D, Klusmann J. GATA1s Exerts Fetal Stage-Specific Oncogenic Effects in Human Hematopoietic Stem and Progenitor Cells Blood. 118: 2355-2355. DOI: 10.1182/Blood.V118.21.2355.2355  0.518
2011 Prashad S, Yao C, Magnusson M, Sasidharan R, Mikkola H. GPI80 Distinguishes Transplantable Human Fetal Hematopoietic Stem Cells From Multipotential Progenitors Blood. 118: 1280-1280. DOI: 10.1182/Blood.V118.21.1280.1280  0.573
2010 Gekas C, Rhodes KE, Van Handel B, Chhabra A, Ueno M, Mikkola HK. Hematopoietic stem cell development in the placenta. The International Journal of Developmental Biology. 54: 1089-98. PMID 20711986 DOI: 10.1387/ijdb.103070cg  0.821
2010 Van Handel B, Prashad SL, Hassanzadeh-Kiabi N, Huang A, Magnusson M, Atanassova B, Chen A, Hamalainen EI, Mikkola HK. The first trimester human placenta is a site for terminal maturation of primitive erythroid cells. Blood. 116: 3321-30. PMID 20628147 DOI: 10.1182/blood-2010-04-279489  0.732
2010 Lee LK, Ueno M, Van Handel B, Mikkola HK. Placenta as a newly identified source of hematopoietic stem cells. Current Opinion in Hematology. 17: 313-8. PMID 20571394 DOI: 10.1097/Moh.0B013E328339F295  0.827
2010 Mikkola HK, Radu CG, Witte ON. Targeting leukemia stem cells. Nature Biotechnology. 28: 237-8. PMID 20212485 DOI: 10.1038/Nbt0310-237  0.434
2010 Mikkola H. Origin of Hematopoietic Stem Cells Blood. 116. DOI: 10.1182/Blood.V116.21.Sci-40.Sci-40  0.578
2010 Chhabra A, Lechner AJ, Acharya A, Ueno M, Van Handel B, Tallquist M, Mikkola H. Essential Function of PDGF-B Signaling In the Placental Microenvironment In Protecting Hematopoietic Progenitors From Erythroid Differentiation. Blood. 116: 1559-1559. DOI: 10.1182/Blood.V116.21.1559.1559  0.712
2010 Rhodes KE, Mikkola HKA. Hematopoietic Stem Cell Development in the Placenta Perinatal Stem Cells. 189-201. DOI: 10.1002/9780470480151.ch12  0.788
2009 Gereige LM, Mikkola HK. DNA methylation is a guardian of stem cell self-renewal and multipotency. Nature Genetics. 41: 1164-6. PMID 19862008 DOI: 10.1038/ng1109-1164  0.317
2009 Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells (Dayton, Ohio). 27: 783-95. PMID 19350678 DOI: 10.1002/Stem.13  0.791
2009 Mikkola H. ESAM: adding to the hematopoietic toolbox. Blood. 113: 2871-2. PMID 19324907 DOI: 10.1182/Blood-2009-01-199794  0.585
2009 Gekas C, Rhodes KE, Gereige LM, Helgadottir H, Ferrari R, Kurdistani SK, Montecino-Rodriguez E, Bassel-Duby R, Olson E, Krivtsov AV, Armstrong S, Orkin SH, Pellegrini M, Mikkola HK. Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood. 113: 3461-71. PMID 19211936 DOI: 10.1182/Blood-2008-07-167577  0.752
2009 Rhodes KE, Van Handel B, Wang M, Wang Y, Chhabra A, Mikkola H. Blood Flow Is Required for the Release of Hematopoietic Stem- and Progenitor Cells From Hemogenic Endothelium in the Placenta. Blood. 114: 698-698. DOI: 10.1182/Blood.V114.22.698.698  0.809
2009 Handel BV, Prashad S, Huang A, Hassanzedeh-Kiabi N, Magnusson M, Atanassova B, Hamalainen E, Chen A, Mikkola H. The First Trimester Human Placenta Is An Embryonic Hematopoietic Organ with An Unexpected Function in Primitive Erythroid Maturation. Blood. 114: 1508-1508. DOI: 10.1182/Blood.V114.22.1508.1508  0.58
2009 Gereige L, Ferrari R, Montel-Hagen A, Pellegrini M, Li X, Kurdistani S, Mikkola H. Specification and Maintenance of the Scl Induced Hematopoietic Stem Cell Fate. Blood. 114: 1504-1504. DOI: 10.1182/Blood.V114.22.1504.1504  0.55
2008 Sankaran VG, Menne TF, Xu J, Akie TE, Lettre G, Van Handel B, Mikkola HK, Hirschhorn JN, Cantor AB, Orkin SH. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science (New York, N.Y.). 322: 1839-42. PMID 19056937 DOI: 10.1126/science.1165409  0.703
2008 Gekas C, Rhodes KE, Mikkola HK. Isolation and visualization of mouse placental hematopoietic stem cells. Current Protocols in Stem Cell Biology. Unit 2A.8.1-2A.8.14. PMID 18729047 DOI: 10.1002/9780470151808.Sc02A08S6  0.758
2008 Elorza A, Hyde B, Mikkola HK, Collins S, Shirihai OS. UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis. The Journal of Biological Chemistry. 283: 30461-70. PMID 18687678 DOI: 10.1074/jbc.M805400200  0.421
2008 Schenke-Layland K, Rhodes KE, Angelis E, Butylkova Y, Heydarkhan-Hagvall S, Gekas C, Zhang R, Goldhaber JI, Mikkola HK, Plath K, MacLellan WR. Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells (Dayton, Ohio). 26: 1537-46. PMID 18450826 DOI: 10.1634/Stemcells.2008-0033  0.786
2008 Magnusson M, Mikkola HK. Hematopoietic stem cells in transit--where's the niche? Cell Stem Cell. 2: 302-4. PMID 18397748 DOI: 10.1016/j.stem.2008.03.017  0.488
2008 Rhodes KE, Gekas C, Wang Y, Lux CT, Francis CS, Chan DN, Conway S, Orkin SH, Yoder MC, Mikkola HK. The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell. 2: 252-63. PMID 18371450 DOI: 10.1016/J.Stem.2008.01.001  0.785
2008 Magnusson M, Romero M, Prashad S, Handel BV, Aivio S, Huang A, Pellegrini M, Mikkola H. Recreating a Human Hematopoietic Stem Cell Niche in Vitro by Unique Stroma Cells from the First Trimester Human Placenta and Fetal Liver Blood. 112: 3568-3568. DOI: 10.1182/Blood.V112.11.3568.3568  0.527
2008 Mikkola H, Haan Gd. The ISSCR Junior Investigators Committee: Moving Forward Together Cell Stem Cell. 3: 389-390. DOI: 10.1016/J.Stem.2008.09.009  0.445
2008 de Bruijn M, Mikkola H, Snoeck H, Keller G. Highlights from Philadelphia: ISSCR 2008 Cell Stem Cell. 3: 259-264. DOI: 10.1016/J.Stem.2008.08.015  0.412
2007 Martinez-Agosto JA, Mikkola HK, Hartenstein V, Banerjee U. The hematopoietic stem cell and its niche: a comparative view. Genes & Development. 21: 3044-60. PMID 18056420 DOI: 10.1101/gad.1602607  0.516
2007 Schenke-Layland K, Angelis E, Rhodes KE, Heydarkhan-Hagvall S, Mikkola HK, Maclellan WR. Collagen IV induces trophoectoderm differentiation of mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 25: 1529-38. PMID 17363553 DOI: 10.1634/Stemcells.2006-0729  0.798
2007 Huang A, Handel BV, Prashad S, Hamalainen E, Magnusson M, Mikkola H. Hematopoiesis in the first trimester human placenta: a model for understanding human stem cell development Fertility and Sterility. 88. DOI: 10.1016/J.Fertnstert.2007.07.224  0.503
2006 Mikkola HK, Orkin SH. The journey of developing hematopoietic stem cells. Development (Cambridge, England). 133: 3733-44. PMID 16968814 DOI: 10.1242/Dev.02568  0.482
2006 Teitell MA, Mikkola HK. Transcriptional activators, repressors, and epigenetic modifiers controlling hematopoietic stem cell development. Pediatric Research. 59: 33R-9R. PMID 16549546 DOI: 10.1203/01.pdr.0000205155.26315.c7  0.5
2005 Mikkola HK, Gekas C, Orkin SH, Dieterlen-Lievre F. Placenta as a site for hematopoietic stem cell development. Experimental Hematology. 33: 1048-54. PMID 16140153 DOI: 10.1016/J.Exphem.2005.06.011  0.532
2005 Gekas C, Dieterlen-Lièvre F, Orkin SH, Mikkola HK. The placenta is a niche for hematopoietic stem cells. Developmental Cell. 8: 365-75. PMID 15737932 DOI: 10.1016/J.Devcel.2004.12.016  0.423
2005 Schlaeger TM, Mikkola HK, Gekas C, Helgadottir HB, Orkin SH. Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development. Blood. 105: 3871-4. PMID 15677556 DOI: 10.1182/Blood-2004-11-4467  0.535
2005 Haigh SE, Elorza AA, Biran I, Zurgil N, Deutsch M, Mikkola H, Shirihai OS. Knockdown of ABCme Impairs Heme Biosynthesis as Revealed by Integrating of RNAi and the LiveCell ® Array. Blood. 106: 3732-3732. DOI: 10.1182/Blood.V106.11.3732.3732  0.454
2004 Schlaeger TM, Schuh A, Flitter S, Fisher A, Mikkola H, Orkin SH, Vyas P, Porcher C. Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1. Molecular and Cellular Biology. 24: 7491-502. PMID 15314159 DOI: 10.1128/Mcb.24.17.7491-7502.2004  0.391
2003 Mikkola HK, Klintman J, Yang H, Hock H, Schlaeger TM, Fujiwara Y, Orkin SH. Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature. 421: 547-51. PMID 12540851 DOI: 10.1038/Nature01345  0.526
2001 Woods NB, Mikkola H, Nilsson E, Olsson K, Trono D, Karlsson S. Lentiviral-mediated gene transfer into haematopoietic stem cells. Journal of Internal Medicine. 249: 339-43. PMID 11298854 DOI: 10.1046/J.1365-2796.2001.00806.X  0.492
2000 Mikkola H, Woods NB, Sjögren M, Helgadottir H, Hamaguchi I, Jacobsen SE, Trono D, Karlsson S. Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells. Journal of Virology. 74: 11911-8. PMID 11090191 DOI: 10.1128/Jvi.74.24.11911-11918.2000  0.449
2000 Woods NB, Fahlman C, Mikkola H, Hamaguchi I, Olsson K, Zufferey R, Jacobsen SE, Trono D, Karlsson S. Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells. Blood. 96: 3725-33. PMID 11090053 DOI: 10.1182/Blood.V96.12.3725.H8003725_3725_3733  0.459
2000 Hamaguchi I, Woods NB, Panagopoulos I, Andersson E, Mikkola H, Fahlman C, Zufferey R, Carlsson L, Trono D, Karlsson S. Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro. Journal of Virology. 74: 10778-84. PMID 11044122 DOI: 10.1128/Jvi.74.22.10778-10784.2000  0.501
2000 Woods NB, Mikkola H, Hamaguchi I, Olsson K, Zufferey R, Jacobsen SE, Trono D, Karlsson S. Lentiviral gene transfer into nod/scid repopulating cells results in monoclonal hematopoiesis with transduced myeloid and lymphoid progeny Blood. 96: 218a.  0.366
1998 Wartiovaara U, Salven P, Mikkola H, Lassila R, Kaukonen J, Joukov V, Orpana A, Ristimäki A, Heikinheimo M, Joensuu H, Alitalo K, Palotie A. Peripheral Blood Platelets Express VEGF-C and VEGF which Are Released during Platelet Activation Thrombosis and Haemostasis. 80: 171-175. DOI: 10.1055/S-0037-1615158  0.338
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