Reuben Kapur - Publications

Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Biochemistry, Cell Biology

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lu X, Tu SW, Chang W, Wan C, Wang J, Zang Y, Ramdas B, Kapur R, Lu X, Cao S, Zhang C. SSMD: a semi-supervised approach for a robust cell type identification and deconvolution of mouse transcriptomics data. Briefings in Bioinformatics. PMID 33230549 DOI: 10.1093/bib/bbaa307  0.32
2020 Cai Z, Lu X, Zhang C, Nelanuthala S, Aguilera F, Hadley A, Ramdas B, Fang F, Nephew KP, Kotzin JJ, Williams A, Henao-Mejia J, Haneline LS, Kapur R. Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by pro-inflammatory cytokine induced lncRNA Morrbid. The Journal of Clinical Investigation. PMID 33090974 DOI: 10.1172/JCI140707  0.32
2020 Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, ... ... Kapur R, et al. Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway. Nature Communications. 11: 3856. PMID 32724180 DOI: 10.1038/S41467-020-17555-0  0.32
2020 Cai Z, Aguilera F, Ramdas B, Daulatabad SV, Srivastava R, Kotzin JJ, Carroll M, Wertheim G, Williams A, Janga SC, Zhang C, Henao-Mejia J, Kapur R. Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells. Cell Reports. 31: 107816. PMID 32579941 DOI: 10.1016/J.Celrep.2020.107816  0.32
2019 Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, ... ... Kapur R, et al. Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway. Nature Communications. 10: 5649. PMID 31827082 DOI: 10.1038/S41467-019-13542-2  0.32
2019 Pandey R, Ramdas B, Wan C, Sandusky G, Mohseni M, Zhang C, Kapur R. SHP2 inhibition reduces leukemogenesis in models of combined genetic and epigenetic mutations. The Journal of Clinical Investigation. PMID 31682240 DOI: 10.1172/Jci130520  0.32
2018 Cai Z, Kotzin JJ, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali RS, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R. Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis. Cell Stem Cell. 23: 833-849.e5. PMID 30526882 DOI: 10.1016/J.Stem.2018.10.013  0.32
2018 Palam LR, Mali RS, Ramdas B, Srivatsan SN, Visconte V, Tiu RV, Vanhaesebroeck B, Roers A, Gerbaulet A, Xu M, Janga SC, Takemoto CM, Paczesny S, Kapur R. Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway. Jci Insight. 3. PMID 29467326 DOI: 10.1172/Jci.Insight.94679  0.32
2017 O'Leary HA, Capitano M, Cooper S, Mantel C, Boswell HS, Kapur R, Ramdas B, Chan R, Deng L, Qu CK, Broxmeyer HE. DPP4 truncated GM-CSF & IL-3 manifest distinct receptor binding & regulatory functions compared to their full length forms. Leukemia. PMID 28344320 DOI: 10.1038/Leu.2017.98  0.32
2017 Ghosh J, Kapur R. Role of mTORC1-S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia. Experimental Hematology. PMID 28342808 DOI: 10.1016/J.Exphem.2017.02.004  0.32
2016 Ghosh J, Kobayashi M, Ramdas B, Chatterjee A, Ma P, Mali RS, Carlesso N, Liu Y, Plas DR, Chan RJ, Kapur R. S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance. The Journal of Clinical Investigation. PMID 27294524 DOI: 10.1172/Jci84565  0.32
2016 Zhang H, Rodriguez S, Wang L, Wang S, Serezani H, Kapur R, Cardoso AA, Carlesso N. Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88. Stem Cell Reports. PMID 27264973 DOI: 10.1016/J.Stemcr.2016.05.002  0.32
2016 Richine BM, Virts EL, Bowling JD, Ramdas B, Mali R, Naoye R, Liu Z, Zhang ZY, Boswell HS, Kapur R, Chan RJ. Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia. Leukemia. PMID 27256702 DOI: 10.1038/Leu.2016.131  0.32
2016 Li XJ, Deng L, Brandt SL, Goodwin CB, Ma P, Yang Z, Mali RS, Liu Z, Kapur R, Serezani CH, Chan RJ. Role of p85α in neutrophil extra- and intracellular reactive oxygen species generation. Oncotarget. PMID 27049833 DOI: 10.18632/Oncotarget.8500  0.32
2016 Kapur R, Shi J, Ghosh J, Munugalavadla V, Sims E, Martin H, Wei L, Mali RS. ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells. Oncotarget. PMID 26943578 DOI: 10.18632/Oncotarget.7851  0.32
2015 Chatterjee A, Ghosh J, Kapur R. Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder. Oncotarget. 6: 18250-64. PMID 26158763 DOI: 10.18632/Oncotarget.4213  0.32
2015 Mantel CR, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Haas DM, Falah N, Kapur R, Pelus LM, Bardeesy N, et al. Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock. Cell. 161: 1553-65. PMID 26073944 DOI: 10.1016/J.Cell.2015.04.054  0.32
2015 Gao R, Chen S, Kobayashi M, Yu H, Zhang Y, Wan Y, Young SK, Soltis A, Yu M, Vemula S, Fraenkel E, Cantor A, Antipin Y, Xu Y, Yoder MC, ... ... Kapur R, et al. Bmi1 promotes erythroid development through regulating ribosome biogenesis. Stem Cells (Dayton, Ohio). 33: 925-38. PMID 25385494 DOI: 10.1002/Stem.1896  0.32
2015 Pandey R, Kapur R. Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms Molecular Cancer. 14. DOI: 10.1186/s12943-015-0388-z  0.32
2014 Chatterjee A, Ghosh J, Ramdas B, Mali RS, Martin H, Kobayashi M, Vemula S, Canela VH, Waskow ER, Visconte V, Tiu RV, Smith CC, Shah N, Bunting KD, Boswell HS, ... ... Kapur R, et al. Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis. Cell Reports. 9: 1333-48. PMID 25456130 DOI: 10.1016/J.Celrep.2014.10.039  0.32
2014 Onish C, Mori-Kimachi S, Hirade T, Abe M, Taketani T, Suzumiya J, Sugimoto T, Yamaguchi S, Kapur R, Fukuda S. Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of the Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis. The Journal of Biological Chemistry. 289: 31053-65. PMID 25237195 DOI: 10.1074/Jbc.M114.568287  0.32
2014 Oh SY, Brandal S, Kapur R, Zhu Z, Takemoto CM. Global microRNA expression is essential for murine mast cell development in vivo. Experimental Hematology. 42: 919-23.e1. PMID 25201754 DOI: 10.1016/J.Exphem.2014.07.266  0.32
2014 Kumar S, Xu J, Kumar RS, Lakshmikanthan S, Kapur R, Kofron M, Chrzanowska-Wodnicka M, Filippi MD. The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation. The Journal of Experimental Medicine. 211: 1741-58. PMID 25092872 DOI: 10.1084/Jem.20131706  0.32
2014 Kobayashi M, Shelley WC, Seo W, Vemula S, Lin Y, Liu Y, Kapur R, Taniuchi I, Yoshimoto M. Functional B-1 progenitor cells are present in the hematopoietic stem cell-deficient embryo and depend on Cbfβ for their development. Proceedings of the National Academy of Sciences of the United States of America. 111: 12151-6. PMID 25092306 DOI: 10.1073/Pnas.1407370111  0.32
2014 Sharma N, Everingham S, Zeng LF, Zhang ZY, Kapur R, Craig AW. Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice. Oncotarget. 5: 6130-41. PMID 25026279 DOI: 10.18632/Oncotarget.2177  0.32
2014 Zeng LF, Zhang RY, Yu ZH, Li S, Wu L, Gunawan AM, Lane BS, Mali RS, Li X, Chan RJ, Kapur R, Wells CD, Zhang ZY. Therapeutic potential of targeting the oncogenic SHP2 phosphatase. Journal of Medicinal Chemistry. 57: 6594-609. PMID 25003231 DOI: 10.1021/Jm5006176  0.32
2014 Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka MM, Mu J, Chen DZ, Srour EF, Chitteti BR, HogenEsch H, Tu X, Bellido TM, ... ... Kapur R, et al. Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner. Cell Stem Cell. 15: 51-65. PMID 24996169 DOI: 10.1016/J.Stem.2014.04.021  0.32
2014 Mali RS, Kapur S, Kapur R. Role of Rho kinases in abnormal and normal hematopoiesis. Current Opinion in Hematology. 21: 271-5. PMID 24867289 DOI: 10.1097/Moh.0000000000000056  0.32
2014 Kobayashi M, Bai Y, Dong Y, Yu H, Chen S, Gao R, Zhang L, Yoder MC, Kapur R, Zhang ZY, Liu Y. PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal. Stem Cells (Dayton, Ohio). 32: 1956-67. PMID 24753135 DOI: 10.1002/Stem.1672  0.32
2014 Sharma N, Everingham S, Ramdas B, Kapur R, Craig AW. SHP2 phosphatase promotes mast cell chemotaxis toward stem cell factor via enhancing activation of the Lyn/Vav/Rac signaling axis. Journal of Immunology (Baltimore, Md. : 1950). 192: 4859-66. PMID 24733849 DOI: 10.4049/Jimmunol.1301155  0.32
2014 Surma M, Handy C, Chang J, Kapur R, Wei L, Shi J. ROCK1 deficiency enhances protective effects of antioxidants against apoptosis and cell detachment. Plos One. 9: e90758. PMID 24595357 DOI: 10.1371/Journal.Pone.0090758  0.32
2014 Goodwin CB, Li XJ, Mali RS, Chan G, Kang M, Liu Z, Vanhaesebroeck B, Neel BG, Loh ML, Lannutti BJ, Kapur R, Chan RJ. PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML. Blood. 123: 2838-42. PMID 24553178 DOI: 10.1182/Blood-2013-10-535104  0.32
2014 Stansfield BK, Bessler WK, Mali R, Mund JA, Downing BD, Kapur R, Ingram DA. Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation. The American Journal of Pathology. 184: 79-85. PMID 24211110 DOI: 10.1016/J.Ajpath.2013.09.022  0.32
2013 Martin H, Mali RS, Ma P, Chatterjee A, Ramdas B, Sims E, Munugalavadla V, Ghosh J, Mattingly RR, Visconte V, Tiu RV, Vlaar CP, Dharmawardhane S, Kapur R. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms. The Journal of Clinical Investigation. 123: 4449-63. PMID 24091327 DOI: 10.1172/Jci67509  0.32
2013 Shi J, Wu X, Surma M, Vemula S, Zhang L, Yang Y, Kapur R, Wei L. Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment. Cell Death & Disease. 4: e483. PMID 23392171 DOI: 10.1038/Cddis.2013.10  0.32
2013 Mali RS, Kapur R. Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development. Cell Cycle (Georgetown, Tex.). 12: 7-8. PMID 23255115 DOI: 10.4161/Cc.23070  0.32
2013 Stansfield BK, Bessler WK, Mali R, Mund JA, Downing B, Li F, Sarchet KN, DiStasi MR, Conway SJ, Kapur R, Ingram DA. Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway. Human Molecular Genetics. 22: 977-88. PMID 23197650 DOI: 10.1093/Hmg/Dds502  0.32
2013 Nabinger SC, Li XJ, Ramdas B, He Y, Zhang X, Zeng L, Richine B, Bowling JD, Fukuda S, Goenka S, Liu Z, Feng GS, Yu M, Sandusky GE, Boswell HS, ... ... Kapur R, et al. The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo. Leukemia. 27: 398-408. PMID 23103841 DOI: 10.1038/leu.2012.308  0.32
2012 Mali RS, Chan R, Kapur R. Targeting SHP2 phosphatase in myeloproliferative neoplasms. Oncotarget. 3: 1049-51. PMID 23165317 DOI: 10.18632/Oncotarget.665  0.32
2012 Mali RS, Kapur R. Targeting Rho associated kinases in leukemia and myeloproliferative neoplasms. Oncotarget. 3: 909-10. PMID 23006984 DOI: 10.18632/Oncotarget.664  0.32
2012 Traina F, Visconte V, Jankowska AM, Makishima H, O'Keefe CL, Elson P, Han Y, Hsieh FH, Sekeres MA, Mali RS, Kalaycio M, Lichtin AE, Advani AS, Duong HK, Copelan E, ... Kapur R, et al. Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis. Plos One. 7: e43090. PMID 22905207 DOI: 10.1371/Journal.Pone.0043090  0.32
2012 Vemula S, Shi J, Mali RS, Ma P, Liu Y, Hanneman P, Koehler KR, Hashino E, Wei L, Kapur R. ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53. Blood. 120: 2868-78. PMID 22889758 DOI: 10.1182/Blood-2011-10-384172  0.32
2012 Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, ... ... Kapur R, et al. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 150: 575-89. PMID 22863010 DOI: 10.1016/J.Cell.2012.06.032  0.32
2012 Hu P, Nebreda AR, Liu Y, Carlesso N, Kaplan M, Kapur R. p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals. The Journal of Biological Chemistry. 287: 33215-26. PMID 22859305 DOI: 10.1074/Jbc.M112.355594  0.32
2012 Mali RS, Ma P, Zeng LF, Martin H, Ramdas B, He Y, Sims E, Nabinger S, Ghosh J, Sharma N, Munugalavadla V, Chatterjee A, Li S, Sandusky G, Craig AW, ... ... Kapur R, et al. Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT. Blood. 120: 2669-78. PMID 22806893 DOI: 10.1182/Blood-2011-08-375873  0.32
2012 Gallo RM, Khan MA, Shi J, Kapur R, Wei L, Bailey JC, Liu J, Brutkiewicz RR. Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d. Journal of Immunology (Baltimore, Md. : 1950). 189: 1689-98. PMID 22798677 DOI: 10.4049/Jimmunol.1101484  0.32
2012 Sharma N, Kumar V, Everingham S, Mali RS, Kapur R, Zeng LF, Zhang ZY, Feng GS, Hartmann K, Roers A, Craig AW. SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice. Molecular and Cellular Biology. 32: 2653-63. PMID 22566685 DOI: 10.1128/Mcb.00308-12  0.32
2012 Hu P, Carlesso N, Xu M, Liu Y, Nebreda AR, Takemoto C, Kapur R. Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms. The Journal of Biological Chemistry. 287: 20258-69. PMID 22518842 DOI: 10.1074/Jbc.M112.358119  0.32
2012 Ruschmann J, Antignano F, Lam V, Snyder K, Kim C, Essak M, Zhang A, Lin AH, Mali RS, Kapur R, Krystal G. The role of SHIP in the development and activation of mouse mucosal and connective tissue mast cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 3839-50. PMID 22430739 DOI: 10.4049/Jimmunol.1003875  0.32
2012 Krishnan S, Mali RS, Ramdas B, Sims E, Ma P, Ghosh J, Munugalavadla V, Hanneman P, Beane JD, Kapur R. p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis. Blood. 119: 3951-61. PMID 22378847 DOI: 10.1182/Blood-2011-05-355602  0.32
2012 Ma P, Mali RS, Martin H, Ramdas B, Sims E, Kapur R. Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease. Leukemia. 26: 1499-506. PMID 22297723 DOI: 10.1038/Leu.2012.22  0.32
2012 Krishnan S, Mali RS, Koehler KR, Vemula S, Chatterjee A, Ghosh J, Ramdas B, Ma P, Hashino E, Kapur R. Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes. Plos One. 7: e28979. PMID 22238586 DOI: 10.1371/Journal.Pone.0028979  0.32
2012 Wu L, Yan C, Czader M, Foreman O, Blum JS, Kapur R, Du H. Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis. Blood. 119: 115-26. PMID 22053106 DOI: 10.1182/Blood-2011-06-363093  0.32
2011 Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, ... ... Kapur R, et al. Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. Cancer Cell. 20: 357-69. PMID 21907926 DOI: 10.1016/J.Ccr.2011.07.016  0.32
2011 Qu P, Yan C, Blum JS, Kapur R, Du H. Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice. Journal of Immunology (Baltimore, Md. : 1950). 187: 3854-66. PMID 21900179 DOI: 10.4049/Jimmunol.1003358  0.32
2011 Ma P, Vemula S, Munugalavadla V, Chen J, Sims E, Borneo J, Kondo T, Ramdas B, Mali RS, Li S, Hashino E, Takemoto C, Kapur R. Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation. Molecular and Cellular Biology. 31: 4052-62. PMID 21791602 DOI: 10.1128/Mcb.05750-11  0.32
2011 Ma P, Mali RS, Munugalavadla V, Krishnan S, Ramdas B, Sims E, Martin H, Ghosh J, Li S, Chan RJ, Krystal G, Craig AW, Takemoto C, Kapur R. The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor. Blood. 118: 3459-69. PMID 21791431 DOI: 10.1182/Blood-2011-04-351809  0.32
2011 Wu X, Chen S, Orlando SA, Yuan J, Kim ET, Munugalavadla V, Mali RS, Kapur R, Yang FC. p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway. The Journal of Biological Chemistry. 286: 13512-21. PMID 21324896 DOI: 10.1074/jbc.M110.187351  0.32
2011 Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM. KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood. 117: 3629-40. PMID 21273305 DOI: 10.1182/blood-2010-07-293548  0.32
2010 Vemula S, Ramdas B, Hanneman P, Martin J, Beggs HE, Kapur R. Essential role for focal adhesion kinase in regulating stress hematopoiesis. Blood. 116: 4103-15. PMID 20664055 DOI: 10.1182/Blood-2010-01-262790  0.32
2010 Lasater EA, Li F, Bessler WK, Estes ML, Vemula S, Hingtgen CM, Dinauer MC, Kapur R, Conway SJ, Ingram DA. Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. The Journal of Clinical Investigation. 120: 859-70. PMID 20160346 DOI: 10.1172/Jci41443  0.32
2010 Vemula S, Shi J, Hanneman P, Wei L, Kapur R. ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Blood. 115: 1785-96. PMID 20008297 DOI: 10.1182/Blood-2009-08-237222  0.32
2010 Benson EA, Goebl MG, Yang FC, Kapur R, McClintick J, Sanghani S, Clapp DW, Harrington MA. Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors. Experimental Hematology. 38: 71-81. PMID 19941935 DOI: 10.1016/J.Exphem.2009.11.006  0.32
2009 Saadatzadeh MR, Bijangi-Vishehsaraei K, Kapur R, Haneline LS. Distinct roles of stress-activated protein kinases in Fanconi anemia-type C-deficient hematopoiesis. Blood. 113: 2655-60. PMID 19168785 DOI: 10.1182/Blood-2008-09-181420  0.32
2008 Munugalavadla V, Vemula S, Sims EC, Krishnan S, Chen S, Yan J, Li H, Niziolek PJ, Takemoto C, Robling AG, Yang FC, Kapur R. The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration. Molecular and Cellular Biology. 28: 7182-98. PMID 18809581 DOI: 10.1128/Mcb.00920-08  0.32
2008 Hong L, Ramdas B, Chen J, Harris C, Wojchowski DM, Kapur R. KIT associated intracellular tyrosines play an essential role in EpoR co-signaling. Cellular Signalling. 20: 1513-20. PMID 18538998 DOI: 10.1016/J.Cellsig.2008.04.005  0.32
2008 Orschell CM, Borneo J, Munugalavadla V, Ma P, Sims E, Ramdas B, Yoder MC, Kapur R. Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells. Experimental Hematology. 36: 655-66. PMID 18346837 DOI: 10.1016/J.Exphem.2008.01.002  0.32
2008 Munugalavadla V, Sims EC, Chan RJ, Lenz SD, Kapur R. Requirement for p85alpha regulatory subunit of class IA PI3K in myeloproliferative disease driven by an activation loop mutant of KIT. Experimental Hematology. 36: 301-8. PMID 18179858 DOI: 10.1016/J.Exphem.2007.11.008  0.32
2007 Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Munugulavadla V, Kapur R, Chen H, Shou W, Stone JC, et al. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. Journal of Immunology (Baltimore, Md. : 1950). 179: 8322-31. PMID 18056377 DOI: 10.4049/Jimmunol.179.12.8322  0.32
2007 Borneo J, Munugalavadla V, Sims EC, Vemula S, Orschell CM, Yoder M, Kapur R. Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors. Experimental Hematology. 35: 1026-37. PMID 17588471 DOI: 10.1016/J.Exphem.2007.03.017  0.32
2007 Thieu VT, Nguyen ET, McCarthy BP, Bruns HA, Kapur R, Chang CH, Kaplan MH. IL-4-stimulated NF-kappaB activity is required for Stat6 DNA binding. Journal of Leukocyte Biology. 82: 370-9. PMID 17513694 DOI: 10.1189/Jlb.1106707  0.32
2007 Munugalavadla V, Sims EC, Borneo J, Chan RJ, Kapur R. Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis. Blood. 110: 1612-20. PMID 17483298 DOI: 10.1182/Blood-2006-10-053058  0.32
2007 Mathur AN, Chang HC, Zisoulis DG, Stritesky GL, Yu Q, O'Malley JT, Kapur R, Levy DE, Kansas GS, Kaplan MH. Stat3 and Stat4 direct development of IL-17-secreting Th cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 4901-7. PMID 17404271 DOI: 10.4049/Jimmunol.178.8.4901  0.32
2006 Wang ZY, Kusam S, Munugalavadla V, Kapur R, Brutkiewicz RR, Dent AL. Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2. Journal of Immunology (Baltimore, Md. : 1950). 176: 880-8. PMID 16393972 DOI: 10.4049/Jimmunol.176.2.880  0.32
2006 Haneline LS, White H, Yang FC, Chen S, Orschell C, Kapur R, Ingram DA. Genetic reduction of class IA PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo. Blood. 107: 1375-82. PMID 16239435 DOI: 10.1182/Blood-2005-05-1985  0.32
2005 Bijangi-Vishehsaraei K, Saadatzadeh MR, Werne A, McKenzie KA, Kapur R, Ichijo H, Haneline LS. Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1. Blood. 106: 4124-30. PMID 16109778 DOI: 10.1182/Blood-2005-05-2096  0.32
2005 Munugalavadla V, Dore LC, Tan BL, Hong L, Vishnu M, Weiss MJ, Kapur R. Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation. Molecular and Cellular Biology. 25: 6747-59. PMID 16024808 DOI: 10.1128/Mcb.25.15.6747-6759.2005  0.32
2005 Munugalavadla V, Kapur R. Role of c-Kit and erythropoietin receptor in erythropoiesis. Critical Reviews in Oncology/Hematology. 54: 63-75. PMID 15780908 DOI: 10.1016/J.Critrevonc.2004.11.005  0.32
2005 Munugalavadla V, Borneo J, Ingram DA, Kapur R. p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration. Blood. 106: 103-9. PMID 15769893 DOI: 10.1182/Blood-2004-10-4041  0.32
2005 Khalaf WF, White H, Wenning MJ, Orazi A, Kapur R, Ingram DA. K-Ras is essential for normal fetal liver erythropoiesis. Blood. 105: 3538-41. PMID 15644420 DOI: 10.1182/Blood-2004-05-2021  0.32
2005 Chan RJ, Leedy MB, Munugalavadla V, Voorhorst CS, Li Y, Yu M, Kapur R. Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor. Blood. 105: 3737-42. PMID 15644411 DOI: 10.1182/Blood-2004-10-4002  0.32
2004 Hiatt K, Ingram DA, Huddleston H, Spandau DF, Kapur R, Clapp DW. Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells. The American Journal of Pathology. 164: 1471-9. PMID 15039234 DOI: 10.1016/S0002-9440(10)63233-6  0.32
2004 Hong L, Munugalavadla V, Kapur R. c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways. Molecular and Cellular Biology. 24: 1401-10. PMID 14729982 DOI: 10.1128/Mcb.24.3.1401-1410.2004  0.32
2003 Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. The Journal of Clinical Investigation. 112: 1851-61. PMID 14679180 DOI: 10.1172/Jci19195  0.32
2003 Tan BL, Hong L, Munugalavadla V, Kapur R. Functional and biochemical consequences of abrogating the activation of multiple diverse early signaling pathways in Kit. Role for Src kinase pathway in Kit-induced cooperation with erythropoietin receptor. The Journal of Biological Chemistry. 278: 11686-95. PMID 12486028 DOI: 10.1074/Jbc.M207068200  0.32
2003 Xie X, Chan RJ, Johnson SA, Starr M, McCarthy J, Kapur R, Yoder MC. Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs. Blood. 101: 1329-35. PMID 12393382 DOI: 10.1182/Blood-2002-05-1468  0.32
2002 Marques SA, Dy LC, Southall MD, Yi Q, Smietana E, Kapur R, Marques M, Travers JB, Spandau DF. The platelet-activating factor receptor activates the extracellular signal-regulated kinase mitogen-activated protein kinase and induces proliferation of epidermal cells through an epidermal growth factor-receptor-dependent pathway. The Journal of Pharmacology and Experimental Therapeutics. 300: 1026-35. PMID 11861812 DOI: 10.1124/Jpet.300.3.1026  0.32
2001 Kapur R, Zhang L. A novel mechanism of cooperation between c-Kit and erythropoietin receptor. Stem cell factor induces the expression of Stat5 and erythropoietin receptor, resulting in efficient proliferation and survival by erythropoietin. The Journal of Biological Chemistry. 276: 1099-106. PMID 11042182 DOI: 10.1074/Jbc.M007442200  0.32
1999 Roberts AW, Kim C, Zhen L, Lowe JB, Kapur R, Petryniak B, Spaetti A, Pollock JD, Borneo JB, Bradford GB, Atkinson SJ, Dinauer MC, Williams DA. Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity. 10: 183-96. PMID 10072071 DOI: 10.1016/S1074-7613(00)80019-9  0.32
1997 Kapur R, Xiao X, McAndrews-Hill M. Sustained activation of erythropoietin receptor by membrane presentation of stem cell factor: a unique in vivo role for membrane-associated scf in erythropoiesis Experimental Hematology. 25: 882.  0.32
1996 Maze R, Kapur R, Williams DA. Genetically modified hematopoietic stem cells expressing o6methylguanine dna methyltransferase via a retrovirus vector protect the lymphoid and stem cell compartments in long-term engrafted animals treated with nitrosourea Journal of Investigative Medicine. 44.  0.32
1995 Kapur R, Evans DL, Harris DT. An evolutionary conserved target cell antigen along with MHC class I molecules influences susceptibility to murine NK cell lysis. Developmental and Comparative Immunology. 19: 347-55. PMID 8617405 DOI: 10.1016/0145-305X(95)00016-M  0.32
1991 Acevedo A, Kapur R, Harris DT. Analysis of an evolutionarily-conserved function-associated molecule (FAM) on murine natural killer (NK) cells Developmental and Comparative Immunology. 15. DOI: 10.1016/0145-305X(91)90337-X  0.32
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