Irina Petrache - Publications

Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Goel K, Schweitzer KS, Serban KA, Bittman R, Petrache I. Pharmacological sphingosine-1 phosphate receptor 1 targeting in cigarette smoke-induced emphysema in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 322: L794-L803. PMID 35412858 DOI: 10.1152/ajplung.00017.2022  0.409
2021 Goel K, Beatman EL, Egersdorf N, Scruggs A, Cao D, Berdyshev EV, Schweitzer KS, Petrache I. Sphingosine 1 Phosphate (S1P) Receptor 1 Is Decreased in Human Lung Microvascular Endothelial Cells of Smokers and Mediates S1P Effect on Autophagy. Cells. 10. PMID 34068927 DOI: 10.3390/cells10051200  0.374
2021 Poczobutt JM, Mikosz AM, Poirier C, Beatman EL, Serban KA, Gally F, Cao D, McCubbrey AL, Cornell CF, Schweitzer KS, Berdyshev EV, Bronova IA, Paris F, Petrache I. Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency. American Journal of Respiratory Cell and Molecular Biology. PMID 33662226 DOI: 10.1165/rcmb.2020-0229OC  0.395
2021 Berdyshev EV, Serban KA, Schweitzer KS, Bronova IA, Mikosz A, Petrache I. Ceramide and sphingosine-1 phosphate in COPD lungs. Thorax. PMID 33514670 DOI: 10.1136/thoraxjnl-2020-215892  0.414
2021 Schweitzer KS, Crue T, Nall JM, Foster D, Sajuthi S, Correll KA, Nakamura M, Everman J, Downey GP, Seibold MA, Bridges JP, Serban KA, Chu HW, Petrache I. Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells. The European Respiratory Journal. PMID 33419885 DOI: 10.1183/13993003.03988-2020  0.318
2020 Summers ME, Richmond BW, Kropski JA, Majka SA, Bastarache JA, Hatzopoulos AK, Bylund J, Ghosh M, Petrache I, Foronjy RF, Geraghty P, Majka SM. Balanced Wnt/Dickkopf1 signaling by mesenchymal vascular progenitor cells in the microvascular niche maintains distal lung structure and function. American Journal of Physiology. Cell Physiology. PMID 33085496 DOI: 10.1152/ajpcell.00277.2020  0.426
2020 Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, ... ... Petrache I, et al. Epithelial cell-specific loss of function of causes a spontaneous COPD-like phenotype and up-regulates expression in mice. Science Advances. 6: eabb7238. PMID 32851183 DOI: 10.1126/Sciadv.Abb7238  0.54
2020 Schweitzer KS, Jinawath N, Yonescu R, Ni K, Rush N, Charoensawan V, Bronova I, Berdyshev E, Leach SM, Gillenwater LA, Bowler RP, Pearse DB, Griffin CA, Petrache I. IGSF3 mutation identified in patient with severe COPD alters cell function and motility. Jci Insight. PMID 32573489 DOI: 10.1172/Jci.Insight.138101  0.471
2020 Gellatly S, Pavelka N, Crue T, Schweitzer KS, Day BJ, Min E, Numata M, Voelker DR, Scruggs A, Petrache I, Chu HW. Nicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells. Journal of Inflammation Research. 13: 175-185. PMID 32368126 DOI: 10.2147/Jir.S244434  0.451
2020 Cao D, Mikosz AM, Ringsby AJ, Anderson KC, Beatman EL, Koike K, Petrache I. MicroRNA-126-3p Inhibits Angiogenic Function of Human Lung Microvascular Endothelial Cell via LAT1 (L-Type Amino Acid Transporter 1)-Mediated mTOR (Mammalian Target of Rapamycin) Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313800. PMID 32212853 DOI: 10.1161/Atvbaha.119.313800  0.373
2020 Kopf KW, Harral JW, Staker EA, Summers ME, Petrache I, Kheyfets V, Irwin DC, Majka SM. Optimization of combined measures of airway physiology and cardiovascular hemodynamics in mice. Pulmonary Circulation. 10: 2045894020912937. PMID 32206308 DOI: 10.1177/2045894020912937  0.492
2020 Tseng V, Ni K, Allawzi A, Prohaska C, Hernandez-Lagunas L, Elajaili H, Cali V, Midura R, Hascall V, Triggs-Raine B, Petrache I, Hart CM, Nozik-Grayck E. Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension. Scientific Reports. 10: 280. PMID 31937874 DOI: 10.1038/S41598-019-57147-7  0.454
2019 Majka SM, Rojas M, Petrache I, Foronjy RF. Mesenchymal Regulation of the Microvascular Niche in Chronic Lung Diseases. Comprehensive Physiology. 9: 1431-1441. PMID 31688970 DOI: 10.1002/Cphy.C180043  0.492
2019 Halper-Stromberg E, Gillenwater L, Cruickshank-Quinn C, O'Neal WK, Reisdorph N, Petrache I, Zhuang Y, Labaki WW, Curtis JL, Wells J, Rennard S, Pratte KA, Woodruff P, Stringer KA, Kechris K, et al. Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma. Metabolites. 9. PMID 31349744 DOI: 10.3390/Metabo9080157  0.355
2019 Koike K, Berdyshev EV, Mikosz AM, Bronova IA, Bronoff AS, Jung JP, Beatman EL, Ni K, Cao D, Scruggs AK, Serban KA, Petrache I. Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema. American Journal of Respiratory and Critical Care Medicine. PMID 31265321 DOI: 10.1164/Rccm.201812-2311Oc  0.532
2019 Koike K, Beatman EL, Schweitzer KS, Justice MJ, Mikosz AM, Ni K, Clauss MA, Petrache I. Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30628489 DOI: 10.1152/Ajplung.00409.2018  0.486
2019 Ni K, Gill A, Cao D, Koike K, Schweitzer KS, Garantziotis S, Petrache I. Intravascular heavy chain-modification of hyaluronan during endotoxic shock. Biochemistry and Biophysics Reports. 17: 114-121. PMID 30623115 DOI: 10.1016/J.Bbrep.2018.12.007  0.437
2018 Schweitzer K, Ni K, Jacobson S, Bronova I, Berdyshev E, Bowler R, Petrache I. The Role of IGSF3 in Cell Adhesion, Proliferation, and Cell Migration. Annals of the American Thoracic Society. 15: S291. PMID 30759008 DOI: 10.1513/Annalsats.201808-586Mg  0.305
2018 Koike K, Berdyshev EV, Bowler RP, Scruggs AK, Cao D, Schweitzer KS, Serban KA, Petrache I. Bioactive Sphingolipids in the Pathogenesis of Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 15: S249-S252. PMID 30759004 DOI: 10.1513/Annalsats.201809-592Mg  0.494
2018 Cruickshank-Quinn CI, Jacobson S, Hughes G, Powell RL, Petrache I, Kechris K, Bowler R, Reisdorph N. Metabolomics and transcriptomics pathway approach reveals outcome-specific perturbations in COPD. Scientific Reports. 8: 17132. PMID 30459441 DOI: 10.1038/S41598-018-35372-W  0.385
2018 Serban KA, Petrache I. Mouse Models of COPD. Methods in Molecular Biology (Clifton, N.J.). 1809: 379-394. PMID 29987802 DOI: 10.1007/978-1-4939-8570-8_25  0.477
2018 Ni K, Gill A, Tseng V, Mikosz AM, Koike K, Beatman EL, Xu CY, Cao D, Gally F, Mould KJ, Serban KA, Schweitzer KS, March KL, Janssen WJ, Nozik-Grayck E, ... ... Petrache I, et al. Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury. Respiratory Research. 19: 107. PMID 29855321 DOI: 10.1186/S12931-018-0812-1  0.453
2018 Barwinska D, Oueini H, Poirier C, Albrecht ME, Bogatcheva NV, Justice MJ, Saliba J, Schweitzer KS, Broxmeyer HE, March KL, Petrache I. AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29745251 DOI: 10.1152/Ajplung.00185.2018  0.536
2018 Barwinska D, Traktuev DO, Merfeld-Clauss S, Cook TG, Lu H, Petrache I, March KL. Cigarette Smoking Impairs Adipose Stromal Cell Vasculogenic Activity and Abrogates Potency to Ameliorate Ischemia. Stem Cells (Dayton, Ohio). PMID 29589872 DOI: 10.1002/Stem.2813  0.411
2018 Frump AL, Selej M, Wood JA, Albrecht M, Yakubov B, Petrache I, Lahm T. Hypoxia Up-regulates Estrogen Receptor β in Pulmonary Artery Endothelial Cells in a HIF-1α Dependent Manner. American Journal of Respiratory Cell and Molecular Biology. PMID 29394091 DOI: 10.1165/Rcmb.2017-0167Oc  0.348
2018 Justice MJ, Bronova I, Schweitzer KS, Poirier C, Blum JS, Berdyshev EV, Petrache I. Inhibition of Acid Sphingomyelinase Disrupts LYNUS Signaling and Triggers Autophagy. Journal of Lipid Research. PMID 29378782 DOI: 10.1194/Jlr.M080242  0.447
2018 Uhl F, Zvarova B, Ahlers B, Hood C, Deng B, Lam Y, Beatman E, Schweitzer K, Petrache I, Weiss D, Wagner D. Characterization of decellularized COPD lung matrices using mass spectrometry proteomics European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Lsc-1085  0.508
2017 Stephenson SE, Wilson CL, Crothers K, Attia EF, Wongtrakool C, Petrache I, Schnapp LM. Impact of HIV Infection on Alpha-1 Antitrypsin in the Lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29351445 DOI: 10.1152/Ajplung.00214.2017  0.351
2017 Mizumura K, Justice MJ, Schweitzer KS, Krishnan S, Bronova I, Berdyshev EV, Hubbard WC, Pewzner-Jung Y, Futerman AH, Choi AMK, Petrache I. Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29196503 DOI: 10.1096/Fj.201700571R  0.489
2017 Sears CR, Zhou H, Justice MJ, Fisher AJ, Saliba J, Lamb I, Wicker J, Schweitzer KS, Petrache I. XPC Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development. American Journal of Respiratory Cell and Molecular Biology. PMID 29111769 DOI: 10.1165/Rcmb.2017-0251Oc  0.454
2017 Ni K, Umair Mukhtar Mian M, Meador C, Gill A, Bawrinska D, Cao D, Justice M, Jiang D, Schaefer N, Schweitzer K, Chu HW, March KL, Petrache I. Oncostatin M and TNF-α induce alpha-1 antitrypsin production in undifferentiated adipose stromal cells. Stem Cells and Development. PMID 28825379 DOI: 10.1089/Scd.2017.0099  0.473
2017 Cruickshank-Quinn C, Powell R, Jacobson S, Kechris K, Bowler RP, Petrache I, Reisdorph N. Metabolomic similarities between bronchoalveolar lavage fluid and plasma in humans and mice. Scientific Reports. 7: 5108. PMID 28698669 DOI: 10.1038/S41598-017-05374-1  0.369
2017 Miller MA, Danhorn T, Cruickshank-Quinn CI, Leach SM, Jacobson S, Strand MJ, Reisdorph NA, Bowler RP, Petrache I, Kechris K. Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma. Plos One. 12: e0178281. PMID 28575117 DOI: 10.1371/Journal.Pone.0178281  0.459
2017 Suratt BT, Ubags NDJ, Rastogi D, Tantisira KG, Marsland BJ, Petrache I, Allen JB, Bates JHT, Holguin F, McCormack MC, Michelakis ED, Black SM, Jain M, Mora AL, Natarajan V, et al. An Official American Thoracic Society Workshop Report: Obesity and Metabolism. An Emerging Frontier in Lung Health and Disease. Annals of the American Thoracic Society. 14: 1050-1059. PMID 28570148 DOI: 10.1513/Annalsats.201703-263Ws  0.342
2017 Serban KA, Petrusca DN, Mikosz A, Poirier C, Lockett AD, Saint L, Justice MJ, Twigg HL, Campos MA, Petrache I. Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure. Plos One. 12: e0176073. PMID 28448535 DOI: 10.1371/Journal.Pone.0176073  0.475
2016 Brown MB, Neves E, Long GM, Graber JB, Gladish BA, Wiseman A, Owens M, Fisher AJ, Presson RG, Petrache I, Kline JA, Lahm T. High Intensity Interval Training but not Continuous Training Reverses Right Ventricular Hypertrophy and Dysfunction in a Rat Model of Pulmonary Hypertension. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00358.2016. PMID 27784688 DOI: 10.1152/Ajpregu.00358.2016  0.301
2016 Ni K, Serban KA, Batra C, Petrache I. Alpha-1 Antitrypsin Investigations Using Animal Models of Emphysema. Annals of the American Thoracic Society. 13: S311-S316. PMID 27564666 DOI: 10.1513/Annalsats.201510-675Kv  0.46
2016 Serban KA, Rezania S, Petrusca DN, Poirier C, Cao D, Justice MJ, Patel M, Tsvetkova I, Kamocki K, Mikosz A, Schweitzer KS, Jacobson S, Cardoso A, Carlesso N, Hubbard WC, ... ... Petrache I, et al. Structural and functional characterization of endothelial microparticles released by cigarette smoke. Scientific Reports. 6: 31596. PMID 27530098 DOI: 10.1038/Srep31596  0.75
2016 Serban KA, Petrache I. Alpha-1 Antitrypsin and Lung Cell Apoptosis. Annals of the American Thoracic Society. 13: S146-9. PMID 27115949 DOI: 10.1513/Annalsats.201505-312Kv  0.523
2016 Petrache I, Berdyshev EV. Ceramide Signaling and Metabolism in Pathophysiological States of the Lung. Annual Review of Physiology. 78: 463-80. PMID 26667073 DOI: 10.1146/Annurev-Physiol-021115-105221  0.496
2015 Lu H, Cook T, Poirier C, Merfeld-Clauss S, Petrache I, March KL, Bogatcheva NV. Pulmonary retention of adipose stromal cell following intravenous delivery is markedly altered in the presence of ARDS. Cell Transplantation. PMID 26609693 DOI: 10.3727/096368915X690189  0.47
2015 Lockett AD, Petrusca DN, Justice MJ, Poirier C, Serban KA, Rush NI, Kamocka M, Predescu DN, Predescu SA, Petrache I. Scavenger Receptor Class B, Type I mediated uptake of A1AT by Pulmonary Endothelial Cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00376.2014. PMID 26092999 DOI: 10.1152/Ajplung.00376.2014  0.495
2015 Schweitzer KS, Chen SX, Law S, Van Demark MJ, Poirier C, Justice MJ, Hubbard WC, Kim ES, Lai X, Wang M, Kranz WD, Carroll CJ, Ray BD, Bittman R, Goodpaster J, ... Petrache I, et al. Endothelial disruptive pro-inflammatory effects of nicotine and e-cigarette vapor exposures. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00411.2015. PMID 25979079 DOI: 10.1152/Ajplung.00411.2014  0.44
2015 Lu H, Poirier C, Cook T, Traktuev DO, Merfeld-Clauss S, Lease B, Petrache I, March KL, Bogatcheva NV. Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis. Journal of Translational Medicine. 13: 67. PMID 25889857 DOI: 10.1186/S12967-015-0422-3  0.447
2015 Brown MB, Chingombe TJ, Zinn AB, Reddy JG, Novack RA, Cooney SA, Fisher AJ, Presson RG, Lahm T, Petrache I. Novel assessment of haemodynamic kinetics with acute exercise in a rat model of pulmonary arterial hypertension. Experimental Physiology. 100: 742-54. PMID 25867528 DOI: 10.1113/Ep085182  0.303
2015 Goss KN, Cucci AR, Fisher AJ, Albrecht M, Frump A, Tursunova R, Gao Y, Brown MB, Petrache I, Tepper RS, Ahlfeld SK, Lahm T. Neonatal hyperoxic lung injury favorably alters adult right ventricular remodeling response to chronic hypoxia exposure. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L797-806. PMID 25659904 DOI: 10.1152/Ajplung.00276.2014  0.379
2015 Christofidou-Solomidou M, Pietrofesa RA, Arguiri E, Schweitzer KS, Berdyshev EV, McCarthy M, Corbitt A, Alwood JS, Yu Y, Globus RK, Solomides CC, Ullrich RL, Petrache I. Space radiation-associated lung injury in a murine model. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L416-28. PMID 25526737 DOI: 10.1152/Ajplung.00260.2014  0.427
2015 Bowler RP, Jacobson S, Cruickshank C, Hughes GJ, Siska C, Ory DS, Petrache I, Schaffer JE, Reisdorph N, Kechris K. Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes. American Journal of Respiratory and Critical Care Medicine. 191: 275-84. PMID 25494452 DOI: 10.1164/Rccm.201410-1771Oc  0.355
2015 Xie J, Broxmeyer HE, Feng D, Schweitzer KS, Yi R, Cook TG, Chitteti BR, Barwinska D, Traktuev DO, Van Demark MJ, Justice MJ, Ou X, Srour EF, Prockop DJ, Petrache I, et al. Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6. Stem Cells (Dayton, Ohio). 33: 468-78. PMID 25329668 DOI: 10.1002/Stem.1851  0.359
2015 McCaslin CA, Petrusca DN, Poirier C, Serban KA, Anderson GG, Petrache I. Impact of alginate-producing Pseudomonas aeruginosa on alveolar macrophage apoptotic cell clearance. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 14: 70-7. PMID 25027418 DOI: 10.1016/J.Jcf.2014.06.009  0.396
2015 Schuchman EH, Clancy J, Dimango E, Petrache I, Gulbins E, He X. Novel use of the lysosomal enzyme acid ceramidase for the treatment of inflammatory lung diseases, including cystic fibrosis Molecular Genetics and Metabolism. 114: S104-S105. DOI: 10.1016/J.Ymgme.2014.12.236  0.403
2014 Zhang X, Shan P, Homer R, Zhang Y, Petrache I, Mannam P, Lee PJ. Cathepsin E promotes pulmonary emphysema via mitochondrial fission. The American Journal of Pathology. 184: 2730-41. PMID 25239563 DOI: 10.1016/J.Ajpath.2014.06.017  0.508
2014 Voiles L, Lewis DE, Han L, Lupov IP, Lin TL, Robertson MJ, Petrache I, Chang HC. Overexpression of type VI collagen in neoplastic lung tissues. Oncology Reports. 32: 1897-904. PMID 25176343 DOI: 10.3892/Or.2014.3438  0.504
2014 Cruickshank-Quinn CI, Mahaffey S, Justice MJ, Hughes G, Armstrong M, Bowler RP, Reisdorph R, Petrache I, Reisdorph N. Transient and persistent metabolomic changes in plasma following chronic cigarette smoke exposure in a mouse model. Plos One. 9: e101855. PMID 25007263 DOI: 10.1371/Journal.Pone.0101855  0.39
2014 Toney BM, Fisher AJ, Albrecht M, Lockett AD, Presson RG, Petrache I, Lahm T. Selective endothelin-A receptor blockade attenuates endotoxin-induced pulmonary hypertension and pulmonary vascular dysfunction. Pulmonary Circulation. 4: 300-10. PMID 25006449 DOI: 10.1086/675993  0.37
2014 Brown MB, Hunt WR, Noe JE, Rush NI, Schweitzer KS, Leece TC, Moldobaeva A, Wagner EM, Dudek SM, Poirier C, Presson RG, Gulbins E, Petrache I. Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier function and increases susceptibility to microvascular damage from cigarette smoke. Pulmonary Circulation. 4: 260-8. PMID 25006445 DOI: 10.1086/675989  0.548
2014 Janes K, Little JW, Li C, Bryant L, Chen C, Chen Z, Kamocki K, Doyle T, Snider A, Esposito E, Cuzzocrea S, Bieberich E, Obeid L, Petrache I, Nicol G, et al. The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. The Journal of Biological Chemistry. 289: 21082-97. PMID 24876379 DOI: 10.1074/Jbc.M114.569574  0.689
2014 Lahm T, Tuder RM, Petrache I. Progress in solving the sex hormone paradox in pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L7-26. PMID 24816487 DOI: 10.1152/Ajplung.00337.2013  0.302
2014 Lockett AD, Brown MB, Santos-Falcon N, Rush NI, Oueini H, Oberle AJ, Bolanis E, Fragoso MA, Petrusca DN, Serban KA, Schweitzer KS, Presson RG, Campos M, Petrache I. Active trafficking of alpha 1 antitrypsin across the lung endothelium. Plos One. 9: e93979. PMID 24743137 DOI: 10.1371/Journal.Pone.0093979  0.571
2014 Green LA, Yi R, Petrusca D, Wang T, Elghouche A, Gupta SK, Petrache I, Clauss M. HIV envelope protein gp120-induced apoptosis in lung microvascular endothelial cells by concerted upregulation of EMAP II and its receptor, CXCR3. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L372-82. PMID 24318111 DOI: 10.1152/Ajplung.00193.2013  0.51
2014 Petrusca DN, Van Demark M, Gu Y, Justice MJ, Rogozea A, Hubbard WC, Petrache I. Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress. American Journal of Respiratory Cell and Molecular Biology. 50: 513-25. PMID 24079644 DOI: 10.1165/Rcmb.2013-0023Oc  0.546
2014 Nobari M, Serban K, Khan B, Petrache I, Diab K. The Effect of Protocolized COPD Management on Lung Function: A Comparison Between Two Groups Chest. 146: 543A. DOI: 10.1378/Chest.1991221  0.398
2013 Petrache I, Kamocki K, Poirier C, Pewzner-Jung Y, Laviad EL, Schweitzer KS, Van Demark M, Justice MJ, Hubbard WC, Futerman AH. Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models. Plos One. 8: e62968. PMID 23690971 DOI: 10.1371/Journal.Pone.0062968  0.768
2013 Petrache I, Petrusca DN. The involvement of sphingolipids in chronic obstructive pulmonary diseases. Handbook of Experimental Pharmacology. 247-64. PMID 23563660 DOI: 10.1007/978-3-7091-1511-4_12  0.486
2013 Lockett AD, Kimani S, Ddungu G, Wrenger S, Tuder RM, Janciauskiene SM, Petrache I. α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α. American Journal of Respiratory Cell and Molecular Biology. 49: 143-50. PMID 23526215 DOI: 10.1165/Rcmb.2012-0515Oc  0.452
2013 Sahu RP, Petrache I, Van Demark MJ, Rashid BM, Ocana JA, Tang Y, Yi Q, Turner MJ, Konger RL, Travers JB. Cigarette smoke exposure inhibits contact hypersensitivity via the generation of platelet-activating factor agonists. Journal of Immunology (Baltimore, Md. : 1950). 190: 2447-54. PMID 23355733 DOI: 10.4049/Jimmunol.1202699  0.334
2013 Bardita C, Predescu D, Justice MJ, Petrache I, Predescu S. In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs. Apoptosis : An International Journal On Programmed Cell Death. 18: 57-76. PMID 23054079 DOI: 10.1007/S10495-012-0762-X  0.531
2013 Kamocki K, Van Demark M, Fisher A, Rush NI, Presson RG, Hubbard W, Berdyshev EV, Adamsky S, Feinstein E, Gandjeva A, Tuder RM, Petrache I. RTP801 is required for ceramide-induced cell-specific death in the murine lung. American Journal of Respiratory Cell and Molecular Biology. 48: 87-93. PMID 23024063 DOI: 10.1165/Rcmb.2012-0254Oc  0.797
2012 Green LA, Petrusca D, Rajashekhar G, Gianaris T, Schweitzer KS, Wang L, Justice MJ, Petrache I, Clauss M. Cigarette smoke-induced CXCR3 receptor up-regulation mediates endothelial apoptosis. American Journal of Respiratory Cell and Molecular Biology. 47: 807-14. PMID 22936405 DOI: 10.1165/Rcmb.2012-0132Oc  0.509
2012 Tuder RM, Petrache I. Pathogenesis of chronic obstructive pulmonary disease. The Journal of Clinical Investigation. 122: 2749-55. PMID 22850885 DOI: 10.1172/Jci60324  0.456
2012 Lahm T, Petrache I. LC3 as a potential therapeutic target in hypoxia-induced pulmonary hypertension. Autophagy. 8: 1146-7. PMID 22627195 DOI: 10.4161/Auto.20520  0.426
2012 Lahm T, Albrecht M, Fisher AJ, Selej M, Patel NG, Brown JA, Justice MJ, Brown MB, Van Demark M, Trulock KM, Dieudonne D, Reddy JG, Presson RG, Petrache I. 17β-Estradiol attenuates hypoxic pulmonary hypertension via estrogen receptor-mediated effects. American Journal of Respiratory and Critical Care Medicine. 185: 965-80. PMID 22383500 DOI: 10.1164/Rccm.201107-1293Oc  0.335
2012 Lockett AD, Van Demark M, Gu Y, Schweitzer KS, Sigua N, Kamocki K, Fijalkowska I, Garrison J, Fisher AJ, Serban K, Wise RA, Flotte TR, Mueller C, Presson RG, Petrache HI, ... ... Petrache I, et al. Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases. Molecular Medicine (Cambridge, Mass.). 18: 445-54. PMID 22245800 DOI: 10.2119/Molmed.2011.00207  0.752
2012 Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AO, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, ... ... Petrache I, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice (Journal of Clinical Investigation (2011) 121, 6 (2470-2479) DOI: 10.1172/JCI43881) Journal of Clinical Investigation. 122: 2703. DOI: 10.1172/Jci64369  0.773
2012 Justice MJ, Petrusca DN, Williams J, Schweitzer KS, Petrache I, Wassall SR, Petrache HI. Engulfment of Model Membranes by Alveolar Macrophages Biophysical Journal. 102: 502a. DOI: 10.1016/J.Bpj.2011.11.2750  0.305
2011 Petrache I, Petrusca DN, Bowler RP, Kamocki K. Involvement of ceramide in cell death responses in the pulmonary circulation. Proceedings of the American Thoracic Society. 8: 492-6. PMID 22052925 DOI: 10.1513/pats.201104-034MW  0.769
2011 Devlin CM, Lahm T, Hubbard WC, Van Demark M, Wang KC, Wu X, Bielawska A, Obeid LM, Ivan M, Petrache I. Dihydroceramide-based response to hypoxia. The Journal of Biological Chemistry. 286: 38069-78. PMID 21914808 DOI: 10.1074/Jbc.M111.297994  0.36
2011 Schweitzer KS, Hatoum H, Brown MB, Gupta M, Justice MJ, Beteck B, Van Demark M, Gu Y, Presson RG, Hubbard WC, Petrache I. Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L836-46. PMID 21873444 DOI: 10.1152/Ajplung.00385.2010  0.553
2011 Presson RG, Brown MB, Fisher AJ, Sandoval RM, Dunn KW, Lorenz KS, Delp EJ, Salama P, Molitoris BA, Petrache I. Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact. The American Journal of Pathology. 179: 75-82. PMID 21703395 DOI: 10.1016/J.Ajpath.2011.03.048  0.377
2011 Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AÖ, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, ... ... Petrache I, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. The Journal of Clinical Investigation. 121: 2470-9. PMID 21576822 DOI: 10.1172/Jci43881  0.805
2011 Sehra S, Yao W, Nguyen ET, Ahyi AN, Tuana FM, Ahlfeld SK, Snider P, Tepper RS, Petrache I, Conway SJ, Kaplan MH. Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. Journal of Immunology (Baltimore, Md. : 1950). 186: 4959-66. PMID 21402898 DOI: 10.4049/Jimmunol.1002359  0.409
2011 Schweitzer KS, Johnstone BH, Garrison J, Rush NI, Cooper S, Traktuev DO, Feng D, Adamowicz JJ, Van Demark M, Fisher AJ, Kamocki K, Brown MB, Presson RG, Broxmeyer HE, March KL, ... Petrache I, et al. Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking. American Journal of Respiratory and Critical Care Medicine. 183: 215-25. PMID 20709815 DOI: 10.1164/Rccm.201001-0126Oc  0.778
2011 Justice MJ, Rogozea AL, Petrusca DN, Schweitzer K, Petrache I, Wassall SR, Petrache HI. The Role of Ceramide in the Clearence of Apoptotic Cells Biophysical Journal. 100: 409a. DOI: 10.1016/J.Bpj.2010.12.2427  0.343
2010 Tuder RM, Janciauskiene SM, Petrache I. Lung disease associated with alpha1-antitrypsin deficiency. Proceedings of the American Thoracic Society. 7: 381-6. PMID 21030517 DOI: 10.1513/pats.201002-020AW  0.384
2010 Petrusca DN, Gu Y, Adamowicz JJ, Rush NI, Hubbard WC, Smith PA, Berdyshev EV, Birukov KG, Lee CH, Tuder RM, Twigg HL, Vandivier RW, Petrache I. Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. The Journal of Biological Chemistry. 285: 40322-32. PMID 20956540 DOI: 10.1074/Jbc.M110.137604  0.551
2010 Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, Richter A, Brown E, Ashush H, Notkin N, Gelfand A, ... ... Petrache I, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nature Medicine. 16: 767-73. PMID 20473305 DOI: 10.1038/Nm.2157  0.529
2010 Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, Gu Y, Schweitzer KS, Skobeleva A, Rajashekhar G, Hubbard WC, Berdyshev EV, Petrache I. Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. American Journal of Respiratory and Critical Care Medicine. 181: 344-52. PMID 19965812 DOI: 10.1164/Rccm.200906-0826Oc  0.767
2010 Justice MJ, Rogozea AL, Petrusca DN, Petrache I, Wassall SR, Petrache HI. The Effect of Ceramide on Model Membranes and Apoptotic Cells Determined by X-Ray Scattering, Solid State NMR, and Flow Cytometry Biophysical Journal. 98: 465a-466a. DOI: 10.1016/J.Bpj.2009.12.2530  0.375
2009 Petrache I, Hajjar J, Campos M. Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency. Biologics : Targets & Therapy. 3: 193-204. PMID 19707408 DOI: 10.2147/Btt.S4414  0.43
2009 Rajashekhar G, Mitnacht-Kraus R, Ispe U, Garrison J, Hou Y, Taylor B, Petrache I, Vestweber D, Clauss M. A monoclonal rat anti-mouse EMAP II antibody that functionally neutralizes pro- and mature-EMAP II in vitro. Journal of Immunological Methods. 350: 22-8. PMID 19683532 DOI: 10.1016/J.Jim.2009.08.003  0.312
2009 Yamada Y, Sekine Y, Yoshida S, Yasufuku K, Petrache I, Benson HL, Brand DD, Yoshino I, Wilkes DS. Type V collagen-induced oral tolerance plus low-dose cyclosporine prevents rejection of MHC class I and II incompatible lung allografts. Journal of Immunology (Baltimore, Md. : 1950). 183: 237-45. PMID 19542435 DOI: 10.4049/Jimmunol.0804028  0.382
2009 Sohrab S, Petrusca DN, Lockett AD, Schweitzer KS, Rush NI, Gu Y, Kamocki K, Garrison J, Petrache I. Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3149-58. PMID 19423638 DOI: 10.1096/Fj.09-129304  0.799
2009 Noe J, Petrusca D, Rush N, Deng P, VanDemark M, Berdyshev E, Gu Y, Smith P, Schweitzer K, Pilewsky J, Natarajan V, Xu Z, Obukhov AG, Petrache I. CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis. American Journal of Respiratory Cell and Molecular Biology. 41: 314-23. PMID 19168702 DOI: 10.1165/Rcmb.2008-0264Oc  0.556
2008 Iwata T, Philipovskiy A, Fisher AJ, Presson RG, Chiyo M, Lee J, Mickler E, Smith GN, Petrache I, Brand DB, Burlingham WJ, Gopalakrishnan B, Greenspan DS, Christie JD, Wilkes DS. Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction. Journal of Immunology (Baltimore, Md. : 1950). 181: 5738-47. PMID 18832733 DOI: 10.4049/Jimmunol.181.8.5738  0.419
2008 Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. The Journal of Biological Chemistry. 283: 29447-60. PMID 18718906 DOI: 10.1074/Jbc.M804595200  0.569
2008 Cao L, Petrusca DN, Satpathy M, Nakshatri H, Petrache I, Matei D. Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling. Carcinogenesis. 29: 1893-900. PMID 18667446 DOI: 10.1093/Carcin/Bgn158  0.349
2008 Petrache I, Diab K, Knox KS, Twigg HL, Stephens RS, Flores S, Tuder RM. HIV associated pulmonary emphysema: a review of the literature and inquiry into its mechanism. Thorax. 63: 463-9. PMID 18443163 DOI: 10.1136/Thx.2007.079111  0.397
2008 Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, Berdyshev EV, Lungarella G, Tuder RM. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L44-53. PMID 18441093 DOI: 10.1152/Ajplung.00448.2007  0.787
2008 Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I. Apoptotic sphingolipid signaling by ceramides in lung endothelial cells. American Journal of Respiratory Cell and Molecular Biology. 38: 639-46. PMID 18192502 DOI: 10.1165/Rcmb.2007-0274Oc  0.777
2008 Nonas SA, Petrache I, Garcia JGN. Cigarette Smoking, Emphysema and Lung Endothelium Chronic Obstructive Pulmonary Disease. 300-307. DOI: 10.1002/9780470755976.ch27  0.371
2007 Tuder RM, Petrache I. Molecular multitasking in the airspace: alpha1-antitrypsin takes on thrombin and plasmin. American Journal of Respiratory Cell and Molecular Biology. 37: 130-4. PMID 17541009 DOI: 10.1165/Rcmb.2007-0163Tr  0.526
2006 Tuder RM, Yoshida T, Fijalkowka I, Biswal S, Petrache I. Role of lung maintenance program in the heterogeneity of lung destruction in emphysema. Proceedings of the American Thoracic Society. 3: 673-9. PMID 17065372 DOI: 10.1513/pats.200605-124SF  0.459
2006 Petrache I, Fijalkowska I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR, Tuder RM. alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis. The American Journal of Pathology. 169: 1155-66. PMID 17003475 DOI: 10.2353/Ajpath.2006.060058  0.547
2006 Petrache I, Natarajan V, Zhen L, Medler TR, Richter A, Berdyshev EV, Tuder RM. Ceramide causes pulmonary cell apoptosis and emphysema: a role for sphingolipid homeostasis in the maintenance of alveolar cells. Proceedings of the American Thoracic Society. 3: 510. PMID 16921130 DOI: 10.1513/pats.200603-071MS  0.344
2006 Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I. State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective. Proceedings of the American Thoracic Society. 3: 503-10. PMID 16921129 DOI: 10.1513/pats.200603-054MS  0.312
2006 Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, et al. A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema. American Journal of Respiratory and Critical Care Medicine. 173: 1222-8. PMID 16514110 DOI: 10.1164/Rccm.200512-1842Oc  0.506
2006 Wagner EM, Petrache I, Schofield B, Mitzner W. Pulmonary ischemia induces lung remodeling and angiogenesis. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 587-93. PMID 16210444 DOI: 10.1152/Japplphysiol.00029.2005  0.52
2005 Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nature Medicine. 11: 491-8. PMID 15852018 DOI: 10.1038/Nm1238  0.565
2004 Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. The Journal of Clinical Investigation. 114: 1248-59. PMID 15520857 DOI: 10.1172/Jci21146  0.522
2003 Petrache I, Crow MT, Neuss M, Garcia JG. Central involvement of Rho family GTPases in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. Biochemical and Biophysical Research Communications. 306: 244-9. PMID 12788095 DOI: 10.1016/S0006-291X(03)00945-8  0.404
2003 Petrache I, Birukova A, Ramirez SI, Garcia JG, Verin AD. The role of the microtubules in tumor necrosis factor-alpha-induced endothelial cell permeability. American Journal of Respiratory Cell and Molecular Biology. 28: 574-81. PMID 12707013 DOI: 10.1165/Rcmb.2002-0075Oc  0.386
2003 Petrache I, Birukov K, Zaiman AL, Crow MT, Deng H, Wadgaonkar R, Romer LH, Garcia JG. Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 407-16. PMID 12631580 DOI: 10.1096/Fj.02-0672Com  0.401
2001 Petrache I, Verin AD, Crow MT, Birukova A, Liu F, Garcia JGN. Differential effect of MLC kinase in TNF-α-induced endothelial cell apoptosis and barrier dysfunction American Journal of Physiology - Lung Cellular and Molecular Physiology. 280. PMID 11350795 DOI: 10.1152/Ajplung.2001.280.6.L1168  0.399
2000 Petrache I, Otterbein LE, Alam J, Wiegand GW, Choi AMK. Heme oxygenase-1 inhibits TNF-α-induced apoptosis in cultured fibroblasts American Journal of Physiology - Lung Cellular and Molecular Physiology. 278. PMID 10666115 DOI: 10.1152/Ajplung.2000.278.2.L312  0.346
1999 Petrache I, Choi ME, Otterbein LE, Chin BY, Mantell LL, Horowitz S, Choi AM. Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells. The American Journal of Physiology. 277: L589-95. PMID 10484467 DOI: 10.1152/Ajplung.1999.277.3.L589  0.384
1999 Otterbein LE, Lee PJ, Chin BY, Petrache I, Camhi SL, Alam J, Choi AM. Protective effects of heme oxygenase-1 in acute lung injury. Chest. 116: 61S-63S. PMID 10424595 DOI: 10.1378/Chest.116.Suppl_1.61S-A  0.4
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