Irina Petrache - Publications

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry

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Year Citation  Score
2023 Mikosz A, Ni K, Gally F, Pratte KA, Winfree S, Lin Q, Echelman I, Wetmore B, Cao D, Justice MJ, Sandhaus RA, Maier L, Strange C, Bowler RP, Petrache I, et al. Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 37814796 DOI: 10.1152/ajplung.00023.2023  0.394
2023 Tesfaigzi Y, Curtis JL, Petrache I, Polverino F, Kheradmand F, Adcock IM, Rennard SI. Does COPD Originate from Different Cell Types? American Journal of Respiratory Cell and Molecular Biology. PMID 37584669 DOI: 10.1165/rcmb.2023-0175PS  0.305
2023 Staquicini DI, Cardó-Vila M, Rotolo JA, Staquicini FI, Tang FHF, Smith TL, Ganju A, Schiavone C, Dogra P, Wang Z, Cristini V, Giordano RJ, Ozawa MG, Driessen WHP, Proneth B, ... ... Petrache I, et al. Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220269120. PMID 37579172 DOI: 10.1073/pnas.2220269120  0.343
2023 Petrache I. Unraveling the Distal Lung Destruction in Emphysema. American Journal of Respiratory and Critical Care Medicine. PMID 37450936 DOI: 10.1164/rccm.202307-1198ED  0.364
2023 Crue T, Lee GY, Peng JY, Schaunaman N, Agraval H, Day BJ, Dimasuay KG, Cervantes D, Nouri H, Nichols T, Hartsoe P, Numata M, Petrache I, Chu HW. Single cell RNA-sequencing of human precision-cut lung slices: A novel approach to study the effect of vaping and viral infection on lung health. Innate Immunity. 17534259231181029. PMID 37306239 DOI: 10.1177/17534259231181029  0.365
2023 Petrache I, Pujadas E, Ganju A, Serban KA, Borowiec A, Babbs B, Bronova IA, Egersdorf N, Hume PS, Goel K, Janssen WJ, Berdyshev EV, Cordon-Cardo C, Kolesnick R. Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury. Jci Insight. 8. PMID 37212278 DOI: 10.1172/jci.insight.156104  0.33
2023 Petrache I, Gupta A, Hume PS, Rivera T, Schweitzer KS, Chu HW. Pathogenesis of E-Cigarette Vaping Product Use-Associated Lung Injury (EVALI). Comprehensive Physiology. 13: 4617-4630. PMID 36994770 DOI: 10.1002/cphy.c220022  0.322
2022 Goel K, Egersdorf N, Gill A, Cao D, Collum SD, Jyothula SS, Huang HJ, Sauler M, Lee PJ, Majka S, Karmouty-Quintana H, Petrache I. Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension. Respiratory Research. 23: 349. PMID 36522710 DOI: 10.1186/s12931-022-02267-4  0.338
2022 Hume PS, McClendon J, Kopf KW, Harral JW, Poczobutt JM, McCubbrey AL, Smith BJ, Henson PM, Majka SM, Petrache I, Janssen WJ. Cigarette Smoke-Induced Airspace Disease in Mice Develops Independently of HIF-1a Signaling in Leukocytes. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 35943156 DOI: 10.1152/ajplung.00491.2021  0.374
2022 Goel K, Schweitzer KS, Serban KA, Bittman R, Petrache I. Pharmacological sphingosine-1 phosphate receptor 1 targeting in cigarette smoke-induced emphysema in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 322: L794-L803. PMID 35412858 DOI: 10.1152/ajplung.00017.2022  0.408
2021 Goel K, Beatman EL, Egersdorf N, Scruggs A, Cao D, Berdyshev EV, Schweitzer KS, Petrache I. Sphingosine 1 Phosphate (S1P) Receptor 1 Is Decreased in Human Lung Microvascular Endothelial Cells of Smokers and Mediates S1P Effect on Autophagy. Cells. 10. PMID 34068927 DOI: 10.3390/cells10051200  0.373
2021 Poczobutt JM, Mikosz AM, Poirier C, Beatman EL, Serban KA, Gally F, Cao D, McCubbrey AL, Cornell CF, Schweitzer KS, Berdyshev EV, Bronova IA, Paris F, Petrache I. Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency. American Journal of Respiratory Cell and Molecular Biology. PMID 33662226 DOI: 10.1165/rcmb.2020-0229OC  0.395
2021 Berdyshev EV, Serban KA, Schweitzer KS, Bronova IA, Mikosz A, Petrache I. Ceramide and sphingosine-1 phosphate in COPD lungs. Thorax. PMID 33514670 DOI: 10.1136/thoraxjnl-2020-215892  0.414
2021 Schweitzer KS, Crue T, Nall JM, Foster D, Sajuthi S, Correll KA, Nakamura M, Everman J, Downey GP, Seibold MA, Bridges JP, Serban KA, Chu HW, Petrache I. Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells. The European Respiratory Journal. PMID 33419885 DOI: 10.1183/13993003.03988-2020  0.318
2020 Summers ME, Richmond BW, Kropski JA, Majka SA, Bastarache JA, Hatzopoulos AK, Bylund J, Ghosh M, Petrache I, Foronjy RF, Geraghty P, Majka SM. Balanced Wnt/Dickkopf1 signaling by mesenchymal vascular progenitor cells in the microvascular niche maintains distal lung structure and function. American Journal of Physiology. Cell Physiology. PMID 33085496 DOI: 10.1152/ajpcell.00277.2020  0.426
2020 Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, ... ... Petrache I, et al. Epithelial cell-specific loss of function of causes a spontaneous COPD-like phenotype and up-regulates expression in mice. Science Advances. 6: eabb7238. PMID 32851183 DOI: 10.1126/Sciadv.Abb7238  0.539
2020 Schweitzer KS, Jinawath N, Yonescu R, Ni K, Rush N, Charoensawan V, Bronova I, Berdyshev E, Leach SM, Gillenwater LA, Bowler RP, Pearse DB, Griffin CA, Petrache I. IGSF3 mutation identified in patient with severe COPD alters cell function and motility. Jci Insight. PMID 32573489 DOI: 10.1172/Jci.Insight.138101  0.47
2020 Gellatly S, Pavelka N, Crue T, Schweitzer KS, Day BJ, Min E, Numata M, Voelker DR, Scruggs A, Petrache I, Chu HW. Nicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells. Journal of Inflammation Research. 13: 175-185. PMID 32368126 DOI: 10.2147/Jir.S244434  0.451
2020 Cao D, Mikosz AM, Ringsby AJ, Anderson KC, Beatman EL, Koike K, Petrache I. MicroRNA-126-3p Inhibits Angiogenic Function of Human Lung Microvascular Endothelial Cell via LAT1 (L-Type Amino Acid Transporter 1)-Mediated mTOR (Mammalian Target of Rapamycin) Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313800. PMID 32212853 DOI: 10.1161/Atvbaha.119.313800  0.373
2020 Kopf KW, Harral JW, Staker EA, Summers ME, Petrache I, Kheyfets V, Irwin DC, Majka SM. Optimization of combined measures of airway physiology and cardiovascular hemodynamics in mice. Pulmonary Circulation. 10: 2045894020912937. PMID 32206308 DOI: 10.1177/2045894020912937  0.491
2020 Tseng V, Ni K, Allawzi A, Prohaska C, Hernandez-Lagunas L, Elajaili H, Cali V, Midura R, Hascall V, Triggs-Raine B, Petrache I, Hart CM, Nozik-Grayck E. Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension. Scientific Reports. 10: 280. PMID 31937874 DOI: 10.1038/S41598-019-57147-7  0.454
2019 Majka SM, Rojas M, Petrache I, Foronjy RF. Mesenchymal Regulation of the Microvascular Niche in Chronic Lung Diseases. Comprehensive Physiology. 9: 1431-1441. PMID 31688970 DOI: 10.1002/Cphy.C180043  0.491
2019 Halper-Stromberg E, Gillenwater L, Cruickshank-Quinn C, O'Neal WK, Reisdorph N, Petrache I, Zhuang Y, Labaki WW, Curtis JL, Wells J, Rennard S, Pratte KA, Woodruff P, Stringer KA, Kechris K, et al. Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma. Metabolites. 9. PMID 31349744 DOI: 10.3390/Metabo9080157  0.355
2019 Koike K, Berdyshev EV, Mikosz AM, Bronova IA, Bronoff AS, Jung JP, Beatman EL, Ni K, Cao D, Scruggs AK, Serban KA, Petrache I. Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema. American Journal of Respiratory and Critical Care Medicine. PMID 31265321 DOI: 10.1164/Rccm.201812-2311Oc  0.531
2019 Koike K, Beatman EL, Schweitzer KS, Justice MJ, Mikosz AM, Ni K, Clauss MA, Petrache I. Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30628489 DOI: 10.1152/Ajplung.00409.2018  0.485
2019 Ni K, Gill A, Cao D, Koike K, Schweitzer KS, Garantziotis S, Petrache I. Intravascular heavy chain-modification of hyaluronan during endotoxic shock. Biochemistry and Biophysics Reports. 17: 114-121. PMID 30623115 DOI: 10.1016/J.Bbrep.2018.12.007  0.436
2018 Schweitzer K, Ni K, Jacobson S, Bronova I, Berdyshev E, Bowler R, Petrache I. The Role of IGSF3 in Cell Adhesion, Proliferation, and Cell Migration. Annals of the American Thoracic Society. 15: S291. PMID 30759008 DOI: 10.1513/Annalsats.201808-586Mg  0.304
2018 Koike K, Berdyshev EV, Bowler RP, Scruggs AK, Cao D, Schweitzer KS, Serban KA, Petrache I. Bioactive Sphingolipids in the Pathogenesis of Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 15: S249-S252. PMID 30759004 DOI: 10.1513/Annalsats.201809-592Mg  0.494
2018 Cruickshank-Quinn CI, Jacobson S, Hughes G, Powell RL, Petrache I, Kechris K, Bowler R, Reisdorph N. Metabolomics and transcriptomics pathway approach reveals outcome-specific perturbations in COPD. Scientific Reports. 8: 17132. PMID 30459441 DOI: 10.1038/S41598-018-35372-W  0.385
2018 Serban KA, Petrache I. Mouse Models of COPD. Methods in Molecular Biology (Clifton, N.J.). 1809: 379-394. PMID 29987802 DOI: 10.1007/978-1-4939-8570-8_25  0.477
2018 Ni K, Gill A, Tseng V, Mikosz AM, Koike K, Beatman EL, Xu CY, Cao D, Gally F, Mould KJ, Serban KA, Schweitzer KS, March KL, Janssen WJ, Nozik-Grayck E, ... ... Petrache I, et al. Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury. Respiratory Research. 19: 107. PMID 29855321 DOI: 10.1186/S12931-018-0812-1  0.453
2018 Barwinska D, Oueini H, Poirier C, Albrecht ME, Bogatcheva NV, Justice MJ, Saliba J, Schweitzer KS, Broxmeyer HE, March KL, Petrache I. AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29745251 DOI: 10.1152/Ajplung.00185.2018  0.535
2018 Barwinska D, Traktuev DO, Merfeld-Clauss S, Cook TG, Lu H, Petrache I, March KL. Cigarette Smoking Impairs Adipose Stromal Cell Vasculogenic Activity and Abrogates Potency to Ameliorate Ischemia. Stem Cells (Dayton, Ohio). PMID 29589872 DOI: 10.1002/Stem.2813  0.41
2018 Frump AL, Selej M, Wood JA, Albrecht M, Yakubov B, Petrache I, Lahm T. Hypoxia Up-regulates Estrogen Receptor β in Pulmonary Artery Endothelial Cells in a HIF-1α Dependent Manner. American Journal of Respiratory Cell and Molecular Biology. PMID 29394091 DOI: 10.1165/Rcmb.2017-0167Oc  0.348
2018 Justice MJ, Bronova I, Schweitzer KS, Poirier C, Blum JS, Berdyshev EV, Petrache I. Inhibition of Acid Sphingomyelinase Disrupts LYNUS Signaling and Triggers Autophagy. Journal of Lipid Research. PMID 29378782 DOI: 10.1194/Jlr.M080242  0.446
2018 Uhl F, Zvarova B, Ahlers B, Hood C, Deng B, Lam Y, Beatman E, Schweitzer K, Petrache I, Weiss D, Wagner D. Characterization of decellularized COPD lung matrices using mass spectrometry proteomics European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Lsc-1085  0.507
2017 Stephenson SE, Wilson CL, Crothers K, Attia EF, Wongtrakool C, Petrache I, Schnapp LM. Impact of HIV Infection on Alpha-1 Antitrypsin in the Lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29351445 DOI: 10.1152/Ajplung.00214.2017  0.351
2017 Mizumura K, Justice MJ, Schweitzer KS, Krishnan S, Bronova I, Berdyshev EV, Hubbard WC, Pewzner-Jung Y, Futerman AH, Choi AMK, Petrache I. Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29196503 DOI: 10.1096/Fj.201700571R  0.488
2017 Sears CR, Zhou H, Justice MJ, Fisher AJ, Saliba J, Lamb I, Wicker J, Schweitzer KS, Petrache I. XPC Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development. American Journal of Respiratory Cell and Molecular Biology. PMID 29111769 DOI: 10.1165/Rcmb.2017-0251Oc  0.454
2017 Ni K, Umair Mukhtar Mian M, Meador C, Gill A, Bawrinska D, Cao D, Justice M, Jiang D, Schaefer N, Schweitzer K, Chu HW, March KL, Petrache I. Oncostatin M and TNF-α induce alpha-1 antitrypsin production in undifferentiated adipose stromal cells. Stem Cells and Development. PMID 28825379 DOI: 10.1089/Scd.2017.0099  0.473
2017 Cruickshank-Quinn C, Powell R, Jacobson S, Kechris K, Bowler RP, Petrache I, Reisdorph N. Metabolomic similarities between bronchoalveolar lavage fluid and plasma in humans and mice. Scientific Reports. 7: 5108. PMID 28698669 DOI: 10.1038/S41598-017-05374-1  0.369
2017 Miller MA, Danhorn T, Cruickshank-Quinn CI, Leach SM, Jacobson S, Strand MJ, Reisdorph NA, Bowler RP, Petrache I, Kechris K. Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma. Plos One. 12: e0178281. PMID 28575117 DOI: 10.1371/Journal.Pone.0178281  0.459
2017 Suratt BT, Ubags NDJ, Rastogi D, Tantisira KG, Marsland BJ, Petrache I, Allen JB, Bates JHT, Holguin F, McCormack MC, Michelakis ED, Black SM, Jain M, Mora AL, Natarajan V, et al. An Official American Thoracic Society Workshop Report: Obesity and Metabolism. An Emerging Frontier in Lung Health and Disease. Annals of the American Thoracic Society. 14: 1050-1059. PMID 28570148 DOI: 10.1513/Annalsats.201703-263Ws  0.342
2017 Serban KA, Petrusca DN, Mikosz A, Poirier C, Lockett AD, Saint L, Justice MJ, Twigg HL, Campos MA, Petrache I. Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure. Plos One. 12: e0176073. PMID 28448535 DOI: 10.1371/Journal.Pone.0176073  0.474
2016 Brown MB, Neves E, Long GM, Graber JB, Gladish BA, Wiseman A, Owens M, Fisher AJ, Presson RG, Petrache I, Kline JA, Lahm T. High Intensity Interval Training but not Continuous Training Reverses Right Ventricular Hypertrophy and Dysfunction in a Rat Model of Pulmonary Hypertension. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00358.2016. PMID 27784688 DOI: 10.1152/Ajpregu.00358.2016  0.301
2016 Ni K, Serban KA, Batra C, Petrache I. Alpha-1 Antitrypsin Investigations Using Animal Models of Emphysema. Annals of the American Thoracic Society. 13: S311-S316. PMID 27564666 DOI: 10.1513/Annalsats.201510-675Kv  0.459
2016 Serban KA, Rezania S, Petrusca DN, Poirier C, Cao D, Justice MJ, Patel M, Tsvetkova I, Kamocki K, Mikosz A, Schweitzer KS, Jacobson S, Cardoso A, Carlesso N, Hubbard WC, ... ... Petrache I, et al. Structural and functional characterization of endothelial microparticles released by cigarette smoke. Scientific Reports. 6: 31596. PMID 27530098 DOI: 10.1038/Srep31596  0.748
2016 Serban KA, Petrache I. Alpha-1 Antitrypsin and Lung Cell Apoptosis. Annals of the American Thoracic Society. 13: S146-9. PMID 27115949 DOI: 10.1513/Annalsats.201505-312Kv  0.522
2016 Petrache I, Berdyshev EV. Ceramide Signaling and Metabolism in Pathophysiological States of the Lung. Annual Review of Physiology. 78: 463-80. PMID 26667073 DOI: 10.1146/Annurev-Physiol-021115-105221  0.495
2015 Lu H, Cook T, Poirier C, Merfeld-Clauss S, Petrache I, March KL, Bogatcheva NV. Pulmonary retention of adipose stromal cell following intravenous delivery is markedly altered in the presence of ARDS. Cell Transplantation. PMID 26609693 DOI: 10.3727/096368915X690189  0.469
2015 Lockett AD, Petrusca DN, Justice MJ, Poirier C, Serban KA, Rush NI, Kamocka M, Predescu DN, Predescu SA, Petrache I. Scavenger Receptor Class B, Type I mediated uptake of A1AT by Pulmonary Endothelial Cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00376.2014. PMID 26092999 DOI: 10.1152/Ajplung.00376.2014  0.495
2015 Schweitzer KS, Chen SX, Law S, Van Demark MJ, Poirier C, Justice MJ, Hubbard WC, Kim ES, Lai X, Wang M, Kranz WD, Carroll CJ, Ray BD, Bittman R, Goodpaster J, ... Petrache I, et al. Endothelial disruptive pro-inflammatory effects of nicotine and e-cigarette vapor exposures. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00411.2015. PMID 25979079 DOI: 10.1152/Ajplung.00411.2014  0.44
2015 Lu H, Poirier C, Cook T, Traktuev DO, Merfeld-Clauss S, Lease B, Petrache I, March KL, Bogatcheva NV. Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis. Journal of Translational Medicine. 13: 67. PMID 25889857 DOI: 10.1186/S12967-015-0422-3  0.447
2015 Brown MB, Chingombe TJ, Zinn AB, Reddy JG, Novack RA, Cooney SA, Fisher AJ, Presson RG, Lahm T, Petrache I. Novel assessment of haemodynamic kinetics with acute exercise in a rat model of pulmonary arterial hypertension. Experimental Physiology. 100: 742-54. PMID 25867528 DOI: 10.1113/Ep085182  0.303
2015 Goss KN, Cucci AR, Fisher AJ, Albrecht M, Frump A, Tursunova R, Gao Y, Brown MB, Petrache I, Tepper RS, Ahlfeld SK, Lahm T. Neonatal hyperoxic lung injury favorably alters adult right ventricular remodeling response to chronic hypoxia exposure. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L797-806. PMID 25659904 DOI: 10.1152/Ajplung.00276.2014  0.379
2015 Christofidou-Solomidou M, Pietrofesa RA, Arguiri E, Schweitzer KS, Berdyshev EV, McCarthy M, Corbitt A, Alwood JS, Yu Y, Globus RK, Solomides CC, Ullrich RL, Petrache I. Space radiation-associated lung injury in a murine model. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L416-28. PMID 25526737 DOI: 10.1152/Ajplung.00260.2014  0.427
2015 Bowler RP, Jacobson S, Cruickshank C, Hughes GJ, Siska C, Ory DS, Petrache I, Schaffer JE, Reisdorph N, Kechris K. Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes. American Journal of Respiratory and Critical Care Medicine. 191: 275-84. PMID 25494452 DOI: 10.1164/Rccm.201410-1771Oc  0.355
2015 Xie J, Broxmeyer HE, Feng D, Schweitzer KS, Yi R, Cook TG, Chitteti BR, Barwinska D, Traktuev DO, Van Demark MJ, Justice MJ, Ou X, Srour EF, Prockop DJ, Petrache I, et al. Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6. Stem Cells (Dayton, Ohio). 33: 468-78. PMID 25329668 DOI: 10.1002/Stem.1851  0.359
2015 McCaslin CA, Petrusca DN, Poirier C, Serban KA, Anderson GG, Petrache I. Impact of alginate-producing Pseudomonas aeruginosa on alveolar macrophage apoptotic cell clearance. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 14: 70-7. PMID 25027418 DOI: 10.1016/J.Jcf.2014.06.009  0.396
2015 Schuchman EH, Clancy J, Dimango E, Petrache I, Gulbins E, He X. Novel use of the lysosomal enzyme acid ceramidase for the treatment of inflammatory lung diseases, including cystic fibrosis Molecular Genetics and Metabolism. 114: S104-S105. DOI: 10.1016/J.Ymgme.2014.12.236  0.402
2014 Zhang X, Shan P, Homer R, Zhang Y, Petrache I, Mannam P, Lee PJ. Cathepsin E promotes pulmonary emphysema via mitochondrial fission. The American Journal of Pathology. 184: 2730-41. PMID 25239563 DOI: 10.1016/J.Ajpath.2014.06.017  0.507
2014 Voiles L, Lewis DE, Han L, Lupov IP, Lin TL, Robertson MJ, Petrache I, Chang HC. Overexpression of type VI collagen in neoplastic lung tissues. Oncology Reports. 32: 1897-904. PMID 25176343 DOI: 10.3892/Or.2014.3438  0.503
2014 Cruickshank-Quinn CI, Mahaffey S, Justice MJ, Hughes G, Armstrong M, Bowler RP, Reisdorph R, Petrache I, Reisdorph N. Transient and persistent metabolomic changes in plasma following chronic cigarette smoke exposure in a mouse model. Plos One. 9: e101855. PMID 25007263 DOI: 10.1371/Journal.Pone.0101855  0.389
2014 Toney BM, Fisher AJ, Albrecht M, Lockett AD, Presson RG, Petrache I, Lahm T. Selective endothelin-A receptor blockade attenuates endotoxin-induced pulmonary hypertension and pulmonary vascular dysfunction. Pulmonary Circulation. 4: 300-10. PMID 25006449 DOI: 10.1086/675993  0.369
2014 Brown MB, Hunt WR, Noe JE, Rush NI, Schweitzer KS, Leece TC, Moldobaeva A, Wagner EM, Dudek SM, Poirier C, Presson RG, Gulbins E, Petrache I. Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier function and increases susceptibility to microvascular damage from cigarette smoke. Pulmonary Circulation. 4: 260-8. PMID 25006445 DOI: 10.1086/675989  0.547
2014 Janes K, Little JW, Li C, Bryant L, Chen C, Chen Z, Kamocki K, Doyle T, Snider A, Esposito E, Cuzzocrea S, Bieberich E, Obeid L, Petrache I, Nicol G, et al. The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. The Journal of Biological Chemistry. 289: 21082-97. PMID 24876379 DOI: 10.1074/Jbc.M114.569574  0.687
2014 Lahm T, Tuder RM, Petrache I. Progress in solving the sex hormone paradox in pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L7-26. PMID 24816487 DOI: 10.1152/Ajplung.00337.2013  0.302
2014 Lockett AD, Brown MB, Santos-Falcon N, Rush NI, Oueini H, Oberle AJ, Bolanis E, Fragoso MA, Petrusca DN, Serban KA, Schweitzer KS, Presson RG, Campos M, Petrache I. Active trafficking of alpha 1 antitrypsin across the lung endothelium. Plos One. 9: e93979. PMID 24743137 DOI: 10.1371/Journal.Pone.0093979  0.57
2014 Green LA, Yi R, Petrusca D, Wang T, Elghouche A, Gupta SK, Petrache I, Clauss M. HIV envelope protein gp120-induced apoptosis in lung microvascular endothelial cells by concerted upregulation of EMAP II and its receptor, CXCR3. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L372-82. PMID 24318111 DOI: 10.1152/Ajplung.00193.2013  0.51
2014 Petrusca DN, Van Demark M, Gu Y, Justice MJ, Rogozea A, Hubbard WC, Petrache I. Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress. American Journal of Respiratory Cell and Molecular Biology. 50: 513-25. PMID 24079644 DOI: 10.1165/Rcmb.2013-0023Oc  0.545
2014 Nobari M, Serban K, Khan B, Petrache I, Diab K. The Effect of Protocolized COPD Management on Lung Function: A Comparison Between Two Groups Chest. 146: 543A. DOI: 10.1378/Chest.1991221  0.398
2013 Petrache I, Kamocki K, Poirier C, Pewzner-Jung Y, Laviad EL, Schweitzer KS, Van Demark M, Justice MJ, Hubbard WC, Futerman AH. Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models. Plos One. 8: e62968. PMID 23690971 DOI: 10.1371/Journal.Pone.0062968  0.766
2013 Petrache I, Petrusca DN. The involvement of sphingolipids in chronic obstructive pulmonary diseases. Handbook of Experimental Pharmacology. 247-64. PMID 23563660 DOI: 10.1007/978-3-7091-1511-4_12  0.486
2013 Lockett AD, Kimani S, Ddungu G, Wrenger S, Tuder RM, Janciauskiene SM, Petrache I. α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α. American Journal of Respiratory Cell and Molecular Biology. 49: 143-50. PMID 23526215 DOI: 10.1165/Rcmb.2012-0515Oc  0.452
2013 Sahu RP, Petrache I, Van Demark MJ, Rashid BM, Ocana JA, Tang Y, Yi Q, Turner MJ, Konger RL, Travers JB. Cigarette smoke exposure inhibits contact hypersensitivity via the generation of platelet-activating factor agonists. Journal of Immunology (Baltimore, Md. : 1950). 190: 2447-54. PMID 23355733 DOI: 10.4049/Jimmunol.1202699  0.333
2013 Bardita C, Predescu D, Justice MJ, Petrache I, Predescu S. In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs. Apoptosis : An International Journal On Programmed Cell Death. 18: 57-76. PMID 23054079 DOI: 10.1007/S10495-012-0762-X  0.531
2013 Kamocki K, Van Demark M, Fisher A, Rush NI, Presson RG, Hubbard W, Berdyshev EV, Adamsky S, Feinstein E, Gandjeva A, Tuder RM, Petrache I. RTP801 is required for ceramide-induced cell-specific death in the murine lung. American Journal of Respiratory Cell and Molecular Biology. 48: 87-93. PMID 23024063 DOI: 10.1165/Rcmb.2012-0254Oc  0.795
2012 Green LA, Petrusca D, Rajashekhar G, Gianaris T, Schweitzer KS, Wang L, Justice MJ, Petrache I, Clauss M. Cigarette smoke-induced CXCR3 receptor up-regulation mediates endothelial apoptosis. American Journal of Respiratory Cell and Molecular Biology. 47: 807-14. PMID 22936405 DOI: 10.1165/Rcmb.2012-0132Oc  0.508
2012 Tuder RM, Petrache I. Pathogenesis of chronic obstructive pulmonary disease. The Journal of Clinical Investigation. 122: 2749-55. PMID 22850885 DOI: 10.1172/Jci60324  0.456
2012 Lahm T, Petrache I. LC3 as a potential therapeutic target in hypoxia-induced pulmonary hypertension. Autophagy. 8: 1146-7. PMID 22627195 DOI: 10.4161/Auto.20520  0.426
2012 Lahm T, Albrecht M, Fisher AJ, Selej M, Patel NG, Brown JA, Justice MJ, Brown MB, Van Demark M, Trulock KM, Dieudonne D, Reddy JG, Presson RG, Petrache I. 17β-Estradiol attenuates hypoxic pulmonary hypertension via estrogen receptor-mediated effects. American Journal of Respiratory and Critical Care Medicine. 185: 965-80. PMID 22383500 DOI: 10.1164/Rccm.201107-1293Oc  0.335
2012 Lockett AD, Van Demark M, Gu Y, Schweitzer KS, Sigua N, Kamocki K, Fijalkowska I, Garrison J, Fisher AJ, Serban K, Wise RA, Flotte TR, Mueller C, Presson RG, Petrache HI, ... ... Petrache I, et al. Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases. Molecular Medicine (Cambridge, Mass.). 18: 445-54. PMID 22245800 DOI: 10.2119/Molmed.2011.00207  0.749
2012 Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AO, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, ... ... Petrache I, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice (Journal of Clinical Investigation (2011) 121, 6 (2470-2479) DOI: 10.1172/JCI43881) Journal of Clinical Investigation. 122: 2703. DOI: 10.1172/Jci64369  0.771
2012 Justice MJ, Petrusca DN, Williams J, Schweitzer KS, Petrache I, Wassall SR, Petrache HI. Engulfment of Model Membranes by Alveolar Macrophages Biophysical Journal. 102: 502a. DOI: 10.1016/J.Bpj.2011.11.2750  0.305
2011 Petrache I, Petrusca DN, Bowler RP, Kamocki K. Involvement of ceramide in cell death responses in the pulmonary circulation. Proceedings of the American Thoracic Society. 8: 492-6. PMID 22052925 DOI: 10.1513/pats.201104-034MW  0.767
2011 Devlin CM, Lahm T, Hubbard WC, Van Demark M, Wang KC, Wu X, Bielawska A, Obeid LM, Ivan M, Petrache I. Dihydroceramide-based response to hypoxia. The Journal of Biological Chemistry. 286: 38069-78. PMID 21914808 DOI: 10.1074/Jbc.M111.297994  0.36
2011 Schweitzer KS, Hatoum H, Brown MB, Gupta M, Justice MJ, Beteck B, Van Demark M, Gu Y, Presson RG, Hubbard WC, Petrache I. Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L836-46. PMID 21873444 DOI: 10.1152/Ajplung.00385.2010  0.552
2011 Presson RG, Brown MB, Fisher AJ, Sandoval RM, Dunn KW, Lorenz KS, Delp EJ, Salama P, Molitoris BA, Petrache I. Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact. The American Journal of Pathology. 179: 75-82. PMID 21703395 DOI: 10.1016/J.Ajpath.2011.03.048  0.377
2011 Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AÖ, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, ... ... Petrache I, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. The Journal of Clinical Investigation. 121: 2470-9. PMID 21576822 DOI: 10.1172/Jci43881  0.803
2011 Sehra S, Yao W, Nguyen ET, Ahyi AN, Tuana FM, Ahlfeld SK, Snider P, Tepper RS, Petrache I, Conway SJ, Kaplan MH. Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. Journal of Immunology (Baltimore, Md. : 1950). 186: 4959-66. PMID 21402898 DOI: 10.4049/Jimmunol.1002359  0.408
2011 Schweitzer KS, Johnstone BH, Garrison J, Rush NI, Cooper S, Traktuev DO, Feng D, Adamowicz JJ, Van Demark M, Fisher AJ, Kamocki K, Brown MB, Presson RG, Broxmeyer HE, March KL, ... Petrache I, et al. Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking. American Journal of Respiratory and Critical Care Medicine. 183: 215-25. PMID 20709815 DOI: 10.1164/Rccm.201001-0126Oc  0.776
2011 Justice MJ, Rogozea AL, Petrusca DN, Schweitzer K, Petrache I, Wassall SR, Petrache HI. The Role of Ceramide in the Clearence of Apoptotic Cells Biophysical Journal. 100: 409a. DOI: 10.1016/J.Bpj.2010.12.2427  0.343
2010 Tuder RM, Janciauskiene SM, Petrache I. Lung disease associated with alpha1-antitrypsin deficiency. Proceedings of the American Thoracic Society. 7: 381-6. PMID 21030517 DOI: 10.1513/pats.201002-020AW  0.383
2010 Petrusca DN, Gu Y, Adamowicz JJ, Rush NI, Hubbard WC, Smith PA, Berdyshev EV, Birukov KG, Lee CH, Tuder RM, Twigg HL, Vandivier RW, Petrache I. Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. The Journal of Biological Chemistry. 285: 40322-32. PMID 20956540 DOI: 10.1074/Jbc.M110.137604  0.55
2010 Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, Richter A, Brown E, Ashush H, Notkin N, Gelfand A, ... ... Petrache I, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nature Medicine. 16: 767-73. PMID 20473305 DOI: 10.1038/Nm.2157  0.528
2010 Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, Gu Y, Schweitzer KS, Skobeleva A, Rajashekhar G, Hubbard WC, Berdyshev EV, Petrache I. Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. American Journal of Respiratory and Critical Care Medicine. 181: 344-52. PMID 19965812 DOI: 10.1164/Rccm.200906-0826Oc  0.765
2010 Justice MJ, Rogozea AL, Petrusca DN, Petrache I, Wassall SR, Petrache HI. The Effect of Ceramide on Model Membranes and Apoptotic Cells Determined by X-Ray Scattering, Solid State NMR, and Flow Cytometry Biophysical Journal. 98: 465a-466a. DOI: 10.1016/J.Bpj.2009.12.2530  0.374
2009 Petrache I, Hajjar J, Campos M. Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency. Biologics : Targets & Therapy. 3: 193-204. PMID 19707408 DOI: 10.2147/Btt.S4414  0.43
2009 Rajashekhar G, Mitnacht-Kraus R, Ispe U, Garrison J, Hou Y, Taylor B, Petrache I, Vestweber D, Clauss M. A monoclonal rat anti-mouse EMAP II antibody that functionally neutralizes pro- and mature-EMAP II in vitro. Journal of Immunological Methods. 350: 22-8. PMID 19683532 DOI: 10.1016/J.Jim.2009.08.003  0.311
2009 Yamada Y, Sekine Y, Yoshida S, Yasufuku K, Petrache I, Benson HL, Brand DD, Yoshino I, Wilkes DS. Type V collagen-induced oral tolerance plus low-dose cyclosporine prevents rejection of MHC class I and II incompatible lung allografts. Journal of Immunology (Baltimore, Md. : 1950). 183: 237-45. PMID 19542435 DOI: 10.4049/Jimmunol.0804028  0.381
2009 Sohrab S, Petrusca DN, Lockett AD, Schweitzer KS, Rush NI, Gu Y, Kamocki K, Garrison J, Petrache I. Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3149-58. PMID 19423638 DOI: 10.1096/Fj.09-129304  0.797
2009 Noe J, Petrusca D, Rush N, Deng P, VanDemark M, Berdyshev E, Gu Y, Smith P, Schweitzer K, Pilewsky J, Natarajan V, Xu Z, Obukhov AG, Petrache I. CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis. American Journal of Respiratory Cell and Molecular Biology. 41: 314-23. PMID 19168702 DOI: 10.1165/Rcmb.2008-0264Oc  0.555
2008 Iwata T, Philipovskiy A, Fisher AJ, Presson RG, Chiyo M, Lee J, Mickler E, Smith GN, Petrache I, Brand DB, Burlingham WJ, Gopalakrishnan B, Greenspan DS, Christie JD, Wilkes DS. Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction. Journal of Immunology (Baltimore, Md. : 1950). 181: 5738-47. PMID 18832733 DOI: 10.4049/Jimmunol.181.8.5738  0.419
2008 Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. The Journal of Biological Chemistry. 283: 29447-60. PMID 18718906 DOI: 10.1074/Jbc.M804595200  0.568
2008 Cao L, Petrusca DN, Satpathy M, Nakshatri H, Petrache I, Matei D. Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling. Carcinogenesis. 29: 1893-900. PMID 18667446 DOI: 10.1093/Carcin/Bgn158  0.348
2008 Petrache I, Diab K, Knox KS, Twigg HL, Stephens RS, Flores S, Tuder RM. HIV associated pulmonary emphysema: a review of the literature and inquiry into its mechanism. Thorax. 63: 463-9. PMID 18443163 DOI: 10.1136/Thx.2007.079111  0.397
2008 Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, Berdyshev EV, Lungarella G, Tuder RM. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L44-53. PMID 18441093 DOI: 10.1152/Ajplung.00448.2007  0.785
2008 Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I. Apoptotic sphingolipid signaling by ceramides in lung endothelial cells. American Journal of Respiratory Cell and Molecular Biology. 38: 639-46. PMID 18192502 DOI: 10.1165/Rcmb.2007-0274Oc  0.775
2008 Nonas SA, Petrache I, Garcia JGN. Cigarette Smoking, Emphysema and Lung Endothelium Chronic Obstructive Pulmonary Disease. 300-307. DOI: 10.1002/9780470755976.ch27  0.37
2007 Tuder RM, Petrache I. Molecular multitasking in the airspace: alpha1-antitrypsin takes on thrombin and plasmin. American Journal of Respiratory Cell and Molecular Biology. 37: 130-4. PMID 17541009 DOI: 10.1165/Rcmb.2007-0163Tr  0.526
2006 Tuder RM, Yoshida T, Fijalkowka I, Biswal S, Petrache I. Role of lung maintenance program in the heterogeneity of lung destruction in emphysema. Proceedings of the American Thoracic Society. 3: 673-9. PMID 17065372 DOI: 10.1513/pats.200605-124SF  0.458
2006 Petrache I, Fijalkowska I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR, Tuder RM. alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis. The American Journal of Pathology. 169: 1155-66. PMID 17003475 DOI: 10.2353/Ajpath.2006.060058  0.546
2006 Petrache I, Natarajan V, Zhen L, Medler TR, Richter A, Berdyshev EV, Tuder RM. Ceramide causes pulmonary cell apoptosis and emphysema: a role for sphingolipid homeostasis in the maintenance of alveolar cells. Proceedings of the American Thoracic Society. 3: 510. PMID 16921130 DOI: 10.1513/pats.200603-071MS  0.343
2006 Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I. State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective. Proceedings of the American Thoracic Society. 3: 503-10. PMID 16921129 DOI: 10.1513/pats.200603-054MS  0.312
2006 Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, et al. A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema. American Journal of Respiratory and Critical Care Medicine. 173: 1222-8. PMID 16514110 DOI: 10.1164/Rccm.200512-1842Oc  0.505
2006 Wagner EM, Petrache I, Schofield B, Mitzner W. Pulmonary ischemia induces lung remodeling and angiogenesis. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 587-93. PMID 16210444 DOI: 10.1152/Japplphysiol.00029.2005  0.52
2005 Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nature Medicine. 11: 491-8. PMID 15852018 DOI: 10.1038/Nm1238  0.564
2004 Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. The Journal of Clinical Investigation. 114: 1248-59. PMID 15520857 DOI: 10.1172/Jci21146  0.521
2003 Petrache I, Crow MT, Neuss M, Garcia JG. Central involvement of Rho family GTPases in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. Biochemical and Biophysical Research Communications. 306: 244-9. PMID 12788095 DOI: 10.1016/S0006-291X(03)00945-8  0.403
2003 Petrache I, Birukova A, Ramirez SI, Garcia JG, Verin AD. The role of the microtubules in tumor necrosis factor-alpha-induced endothelial cell permeability. American Journal of Respiratory Cell and Molecular Biology. 28: 574-81. PMID 12707013 DOI: 10.1165/Rcmb.2002-0075Oc  0.385
2003 Petrache I, Birukov K, Zaiman AL, Crow MT, Deng H, Wadgaonkar R, Romer LH, Garcia JG. Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 407-16. PMID 12631580 DOI: 10.1096/Fj.02-0672Com  0.4
2001 Petrache I, Verin AD, Crow MT, Birukova A, Liu F, Garcia JGN. Differential effect of MLC kinase in TNF-α-induced endothelial cell apoptosis and barrier dysfunction American Journal of Physiology - Lung Cellular and Molecular Physiology. 280. PMID 11350795 DOI: 10.1152/Ajplung.2001.280.6.L1168  0.398
2000 Petrache I, Otterbein LE, Alam J, Wiegand GW, Choi AMK. Heme oxygenase-1 inhibits TNF-α-induced apoptosis in cultured fibroblasts American Journal of Physiology - Lung Cellular and Molecular Physiology. 278. PMID 10666115 DOI: 10.1152/Ajplung.2000.278.2.L312  0.345
1999 Petrache I, Choi ME, Otterbein LE, Chin BY, Mantell LL, Horowitz S, Choi AM. Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells. The American Journal of Physiology. 277: L589-95. PMID 10484467 DOI: 10.1152/Ajplung.1999.277.3.L589  0.384
1999 Otterbein LE, Lee PJ, Chin BY, Petrache I, Camhi SL, Alam J, Choi AM. Protective effects of heme oxygenase-1 in acute lung injury. Chest. 116: 61S-63S. PMID 10424595 DOI: 10.1378/Chest.116.Suppl_1.61S-A  0.399
Low-probability matches (unlikely to be authored by this person)
2014 Justice MJ, Petrusca DN, Rogozea AL, Williams JA, Schweitzer KS, Petrache I, Wassall SR, Petrache HI. Effects of lipid interactions on model vesicle engulfment by alveolar macrophages. Biophysical Journal. 106: 598-609. PMID 24507600 DOI: 10.1016/J.Bpj.2013.12.036  0.291
2022 Schaunaman N, Crue T, Cervantes D, Schweitzer K, Robbins H, Day BJ, Numata M, Petrache I, Chu HW. Electronic cigarette vapor exposure exaggerates the pro-inflammatory response during influenza A viral infection in human distal airway epithelium. Archives of Toxicology. 96: 2319-2328. PMID 35672461 DOI: 10.1007/s00204-022-03305-2  0.291
2018 Serban KA, Mikosz A, Strange C, Janciauskiene SM, Stolk J, Jonigk D, Sandhaus RA, Petrache I. Lectin Complement Pathway in Emphysema. American Journal of Respiratory and Critical Care Medicine. PMID 30557515 DOI: 10.1164/Rccm.201807-1380Le  0.29
2018 Walmsley S, Cruickshank-Quinn C, Quinn K, Zhang X, Petrache I, Bowler RP, Reisdorph R, Reisdorph N. A prototypic small molecule database for bronchoalveolar lavage-based metabolomics. Scientific Data. 5: 180060. PMID 29664467 DOI: 10.1038/Sdata.2018.60  0.289
2016 Petrache I, Serban K. Lost in Trans-IL-6 Signaling: Alveolar Type II Cell Death in Emphysema. American Journal of Respiratory and Critical Care Medicine. 194: 1441-1443. PMID 27976936 DOI: 10.1164/Rccm.201607-1441Ed  0.284
2016 Crothers K, Petrache I, Wongtrakool C, Lee PJ, Schnapp LM, Gharib SA. Widespread activation of immunity and pro-inflammatory programs in peripheral blood leukocytes of HIV-infected patients with impaired lung gas exchange. Physiological Reports. 4. PMID 27117807 DOI: 10.14814/Phy2.12756  0.284
2009 Ndengele MM, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Muscoli C, Petrusca DN, Mollace V, Mazzon E, Li D, Petrache I, Matuschak GM, Salvemini D. Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation. The Journal of Pharmacology and Experimental Therapeutics. 329: 64-75. PMID 19033555 DOI: 10.1124/Jpet.108.146290  0.282
2003 Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema: the missing link. American Journal of Respiratory Cell and Molecular Biology. 28: 551-4. PMID 12707010 DOI: 10.1165/Rcmb.F269  0.279
2015 Brown MB, Chingombe T, Harper R, Weyer J, Bremer B, Cooney S, Fisher A, Cucci A, Presson R, Petrache I, Lahm T. Exercise Does Not Attenuate Disease Progression in a Rat Model of Progressive Pulmonary Arterial Hypertension: 2532 Board #279 May 29, 11 Medicine and Science in Sports and Exercise. 47: 688. DOI: 10.1249/01.Mss.0000478603.09496.84  0.276
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Petrache I, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.275
2006 Petrache I, Arap W, Pasqualini R, Flotte T, Tuder RM. Diagnostic and therapeutic applications of bacteriophage and adeno-associated virus technologies in pulmonary emphysema Nanomedicine: Nanotechnology, Biology and Medicine. 2: 294. DOI: 10.1016/J.Nano.2006.10.082  0.274
2009 Bryant L, Doyle T, Chen Z, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Mazzon E, Petrusca DN, Petrache I, Salvemini D. Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance. Neuroscience Letters. 463: 49-53. PMID 19631718 DOI: 10.1016/J.Neulet.2009.07.051  0.27
2018 Kim C, Jary H, Mortimer K, Schweitzer KS, Curran-Everett D, Gordon S, Petrache I. Effects of Household Air Pollution in Malawi and Human Immunodeficiency Virus Status on Respiratory Symptoms and Inflammation, Injury, and Repair Markers. Annals of the American Thoracic Society. 15: S132-S133. PMID 29676635 DOI: 10.1513/Annalsats.201707-614Mg  0.27
2013 Brown M, Crist J, Gaidoo R, Little N, Fisher A, Presson R, Lahm T, Petrache I. Six Weeks Of Treadmill Training At Mild Relative Exercise Intensity Attenuates Disease Progression In A Rat Model Of Pulmonary Arterial Hypertension Cardiopulmonary Physical Therapy Journal. 24: 42-43. DOI: 10.1097/01823246-201324040-00029  0.267
1999 Petrache I, Choi ME, Otterbein LE, Chin BY, Mantell LL, Horowitz S, Choi AMK. Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L589-L595. PMID 29592447 DOI: 10.1152/ajplung.1999.277.3.L589  0.265
2007 Clauss M, Hou Y, Yoder M, Ingram D, Petrache I, Voswinckel R. EMAP II induces migration of EPC and monocytes via the chemokine receptor CXCR3 The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A379-H  0.263
2014 Brown MB, Chingombe T, Cooney S, Novack R, Crist J, Bremer B, Weyer J, Brown J, Fisher A, Presson R, Cucci A, Petrache I, Lahm T. Exercise Training Ameliorates Cardiomyocyte ‘Glycolytic Switch’ And Improves Aerobic Capacity In Hypoxic Pulmonary Hypertension Rats: 2454 Board #159 May 30, 11 Medicine and Science in Sports and Exercise. 46: 663. DOI: 10.1249/01.Mss.0000495460.65180.Cf  0.262
2014 Presson RG, Petrache I, Brown MB. Intravital microscopy of the lung Advances in Intravital Microscopy: From Basic to Clinical Research. 221-232. DOI: 10.1007/978-94-017-9361-2_11  0.258
2013 Serban K, Diab K, Petrusca D, Lockett A, Petrache I. Acute Exacerbation and Systemic Comorbidities Modulate Circulating Microparticles in COPD Individuals Chest. 144: 684A. DOI: 10.1378/Chest.1702726  0.254
2014 Harper R, Weyer J, Bremer B, Cooney S, Fisher A, Presson R, Lahm T, Petrache I, Brown MB. Exercise Training At Mild Relative Exercise Intensity Does Not Attenuate Disease Progression In A Rat Model Of Severe Pulmonary Arterial Hypertension. Cardiopulmonary Physical Therapy Journal. 25: 131-132. DOI: 10.1097/01823246-201412000-00046  0.251
2016 Brown MB, Neves E, Long G, Novack R, Fisher A, Presson R, Petrache I, Kline J, Lahm T. High Intensity Interval Training is Superior to Continuous Training in a Pulmonary Hypertension Rat Model: 751 Board #67 June 1, 3: 30 PM - 5: 00 PM. Medicine and Science in Sports and Exercise. 48: 204-205. PMID 27359894 DOI: 10.1249/01.Mss.0000485614.73013.0C  0.247
2021 Petrache I, de Boer E. Rapalogs Target the Endothelium to Set the Stage for Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 34618662 DOI: 10.1165/rcmb.2021-0250ED  0.241
2022 Downey GP, Rivera MP, Schnapp L, Petrache I, Roman J, Collishaw K. Be the Change: Advancing Lung Health and Closing the Global Healthcare Gap. American Journal of Respiratory and Critical Care Medicine. 206: 667-669. PMID 36112773 DOI: 10.1164/rccm.202207-1423ED  0.24
2017 Kim C, Jary H, Schweitzer K, Curran-Everett D, Gordon S, Mortimer K, Petrache I. Effect of Household Air Pollution Exposures on Respiratory Symptoms and Systemic Immunoregulatory Cytokines in HIV-Positive Individuals Chest. 152: A821. DOI: 10.1016/J.Chest.2017.08.853  0.233
2024 Petrache I, Riches DW. Reduced Bik expression drives low-grade airway inflammation and increased risk for COPD in females. The Journal of Clinical Investigation. 134. PMID 38357926 DOI: 10.1172/JCI177753  0.232
2020 Tong X, Chaudry Z, Lee CC, Bone RN, Kanojia S, Maddatu J, Sohn P, Weaver SA, Robertson MA, Petrache I, Evans-Molina C, Kono T. Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation. Molecular Metabolism. 100975. PMID 32283079 DOI: 10.1016/J.Molmet.2020.100975  0.231
2011 Gurnev PA, DeMoss P, Schweitzer K, Petrache I, Petrache HI. Interaction of Alpha-1 antitrypsin with Model Membranes Biophysical Journal. 100: 336a-337a. DOI: 10.1016/J.Bpj.2010.12.2042  0.223
2012 Devlin CM, Lahm T, Hubbard WC, Van Demark M, Wang KC, Wu X, Bielawska A, Obeid LM, Ivan M, Petrache I. Dihydroceramide-based response to hypoxia (Journal of Biological Chemistry (2011) 286, (38069-38078)) Journal of Biological Chemistry. 287: 17425. DOI: 10.1074/Jbc.A111.297994  0.211
2019 Petrache I. Is More Better? Promising Biological Effects of Double-Dose Alpha 1-Antitrypsin Therapy. American Journal of Respiratory and Critical Care Medicine. PMID 31063431 DOI: 10.1164/Rccm.201904-0845Ed  0.209
2021 Gillenwater LA, Kechris KJ, Pratte KA, Reisdorph N, Petrache I, Labaki WW, O'Neal W, Krishnan JA, Ortega VE, DeMeo DL, Bowler RP. Metabolomic Profiling Reveals Sex Specific Associations with Chronic Obstructive Pulmonary Disease and Emphysema. Metabolites. 11. PMID 33799786 DOI: 10.3390/metabo11030161  0.2
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Petrache I, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.197
2014 Hughes G, Cruickshank-Quinn C, Reisdorph R, Lutz S, Petrache I, Reisdorph N, Bowler R, Kechris K. MSPrep-Summarization, normalization and diagnostics for processing of mass spectrometry-based metabolomic data Bioinformatics. 30: 133-134. PMID 24174567 DOI: 10.1093/Bioinformatics/Btt589  0.197
2014 Petrache I, Patel D, Wolf KM, Winer-Muram H. Vertebral erosion: an uncommon complication of tracheal tubes. American Journal of Respiratory and Critical Care Medicine. 190: e4. PMID 25025361 DOI: 10.1164/Rccm.201309-1610Im  0.194
2012 Tuder RM, Petrache I. Pathogenesis of chronic obstructive pulmonary disease (Journal of Clinical Investigation (2012) 122, 11 (4300) DOI: 10.1172/JCI66725) Journal of Clinical Investigation. 122: 4300.  0.19
1999 Chin BY, Petrache I, Choi AM, Choi ME. Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages. The Journal of Biological Chemistry. 274: 11362-8. PMID 10196228 DOI: 10.1074/Jbc.274.16.11362  0.17
2020 Liao SY, Petrache I, Fingerlin TE, Maier LA. Association of inhaled and systemic corticosteroid use with Coronavirus Disease 2019 (COVID-19) test positivity in patients with chronic pulmonary diseases. Respiratory Medicine. 176: 106275. PMID 33276252 DOI: 10.1016/j.rmed.2020.106275  0.168
2023 Vukmirovic M, Benam KH, Rose JJ, Turner S, Magin CM, Lagares D, Cohen AH, Kaminski N, Hirota JA, Maher TM, Königshoff M, Mallampalli RK, Sheppard D, Tarran R, Gomer RH, ... ... Petrache I, et al. Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena: An Official American Thoracic Society Report. Annals of the American Thoracic Society. PMID 37903340 DOI: 10.1513/AnnalsATS.202310-872ST  0.165
2020 Gillenwater LA, Pratte KA, Hobbs BD, Cho MH, Zhuang Y, Halper-Stromberg E, Cruickshank-Quinn C, Reisdorph N, Petrache I, Labaki WW, O'Neal WK, Ortega VE, Jones DP, Uppal K, Jacobson S, et al. Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules. Network and Systems Medicine. 3: 159-181. PMID 33987620 DOI: 10.1089/nsm.2020.0009  0.161
2006 Petrache I. An Antiapoptotic Role for  1-Antitrypsin in the Prevention of Emphysema Proceedings of the American Thoracic Society. 3: 549-549. DOI: 10.1513/pats.200603-079MS  0.137
2012 Petrache I, Georas SN. Common pulmonary problems: Cough, hemoptysis, dyspnea, chest pain, and abnormal chest x-ray Principles of Ambulatory Medicine: Seventh Edition. 869-890.  0.135
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Petrache I, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.131
2022 Guntur VP, Nemkov T, de Boer E, Mohning MP, Baraghoshi D, Cendali FI, San-Millán I, Petrache I, D'Alessandro A. Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (PASC). Metabolites. 12. PMID 36355108 DOI: 10.3390/metabo12111026  0.098
2021 Takeda K, Kim SH, Joetham A, Petrache I, Gelfand EW. Therapeutic benefits of recombinant alpha1-antitrypsin IgG1 Fc-fusion protein in experimental emphysema. Respiratory Research. 22: 207. PMID 34271910 DOI: 10.1186/s12931-021-01784-y  0.094
2020 Koslow M, Petrache I. A Finale on EVALI?: The Abated but Not Forgotten Outbreak of Acute Respiratory Illness in Individuals Who Vape. Jama Network Open. 3: e2019366. PMID 33156344 DOI: 10.1001/jamanetworkopen.2020.19366  0.084
2020 Panettieri RA, Kolls JK, Lazarus S, Corder S, Harshman A, Langmack E, Petrache I. Impact of a Respiratory Disease Young Investigators' Forum on the Career Development of Physician-Scientists. Ats Scholar. 1: 243-259. PMID 33870292 DOI: 10.34197/ats-scholar.2019-0018OC  0.08
2021 Petrache I, de Boer E. Cooling off the heated controversy of a safer cigarette: heat-not-burn no better than traditional combustion cigarettes. Thorax. 76: 536. PMID 34161919 DOI: 10.1136/thoraxjnl-2020-216743  0.078
2022 Guntur VP, Modena BD, Manka LA, Eddy JJ, Liao SY, Goldstein NM, Zelarney P, Horn CA, Keith RC, Make BJ, Petrache I, Wechsler ME. Characteristics and outcomes of ambulatory patients with suspected COVID-19 at a respiratory referral center. Respiratory Medicine. 197: 106832. PMID 35462298 DOI: 10.1016/j.rmed.2022.106832  0.061
2011 Burlacu O, Nicodin A, Jurma T, Ioanovici F, Petrache I, Cretu O, Iliescu D, Budisan C. An original stereotactic device for trans-thoracic CT-guided biopsy. An experimental study Timisoara Medical Journal. 61: 141-146.  0.059
2022 de Boer E, Petrache I, Goldstein NM, Olin JT, Keith RC, Modena B, Mohning MP, Yunt ZX, San-Millán I, Swigris JJ. Decreased Fatty Acid Oxidation and Altered Lactate Production during Exercise in Patients with Post-acute COVID-19 Syndrome. American Journal of Respiratory and Critical Care Medicine. 205: 126-129. PMID 34665688 DOI: 10.1164/rccm.202108-1903LE  0.056
2021 Petrache I, Serban KA. Can Metformin Downshift the Gears of Aging to Slow Emphysema Progression? American Journal of Respiratory and Critical Care Medicine. PMID 34191690 DOI: 10.1164/rccm.202105-1273ED  0.047
2012 Balan V, Petrache IA, Popa MI, Butnaru M, Barbu E, Tsibouklis J, Verestiuc L. Biotinylated chitosan-based SPIONs with potential in blood-contacting applications Journal of Nanoparticle Research. 14. DOI: 10.1007/s11051-012-0730-y  0.021
2011 Bǎlan V, Petrache I, Popa MI, Butnaru M, Vereştiuc L. Hemocompatible Biofunctionalized magnetic composites for blood detoxification techniques 2011 E-Health and Bioengineering Conference, Ehb 2011 0.02
2023 Downey GP, Rivera MP, Schnapp LM, Petrache I, Roman J, Collishaw KJ. Considerations in Selecting Venues for the ATS International Conference: Balancing Competing Priorities of the Society's Diverse Membership. Annals of the American Thoracic Society. PMID 36884216 DOI: 10.1513/AnnalsATS.202302-179LE  0.011
2022 de Boer E, Petrache I, Mohning MP. Cardiopulmonary Exercise Testing. Jama. PMID 35266955 DOI: 10.1001/jama.2022.2037  0.01
2013 Gulbins E, Petrache I. Preface Handbook of Experimental Pharmacology. 216.  0.01
2011 Balan V, Verestiuc L, Popa MI, Petrache IA, Butnaru M, Barbu E, Tsibouklis J. Biofunctionalized SPIONs with potential applications in blood detoxifying 24th European Conference On Biomaterials - Annual Conference of the European Society For Biomaterials 0.01
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