Ross C. Hardison, Ph.D. - Publications

Affiliations: 
1980- Biochemistry, Microbiology, and Molecular biology Pennsylvania State University, State College, PA, United States 
Area:
Biochemistry, Molecular Biology, Genomics, Epigenomics, Gene Regulation
Website:
http://www.bx.psu.edu/~ross/

258 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Huang P, Peslak SA, Ren R, Khandros E, Qin K, Keller CA, Giardine B, Bell HW, Lan X, Sharma M, Horton JR, Abdulmalik O, Chou ST, Shi J, Crossley M, ... Hardison RC, et al. HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nature Genetics. PMID 35941187 DOI: 10.1038/s41588-022-01152-6  0.694
2022 Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, et al. Publisher Correction: Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nature Genetics. PMID 35650318 DOI: 10.1038/s41588-022-01112-0  0.611
2022 Wakabayashi A, Kihiu M, Sharma M, Thrasher AJ, Saari MS, Quesnel-Vallieres M, Abdulmalik O, Peslak SA, Khandros E, Keller CA, Giardine BM, Barash Y, Hardison RC, Shi J, Blobel GA. Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression. Blood Advances. PMID 35622975 DOI: 10.1182/bloodadvances.2022007904  0.701
2022 Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, et al. Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nature Genetics. PMID 35618846 DOI: 10.1038/s41588-022-01076-1  0.703
2022 Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, et al. Author Correction: Perspectives on ENCODE. Nature. PMID 35474002 DOI: 10.1038/s41586-021-04213-8  0.663
2022 Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, ... ... Hardison RC, et al. Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature. PMID 35474001 DOI: 10.1038/s41586-021-04226-3  0.813
2021 Zhang H, Lam J, Zhang D, Lan Y, Vermunt MW, Keller CA, Giardine B, Hardison RC, Blobel GA. CTCF and transcription influence chromatin structure re-configuration after mitosis. Nature Communications. 12: 5157. PMID 34453048 DOI: 10.1038/s41467-021-25418-5  0.703
2021 Yan B, Yang J, Kim MY, Luo H, Cesari N, Yang T, Strouboulis J, Zhang J, Hardison R, Huang S, Qiu Y. HDAC1 is required for GATA-1 transcription activity, global chromatin occupancy and hematopoiesis. Nucleic Acids Research. PMID 34450641 DOI: 10.1093/nar/gkab737  0.307
2021 Cheng L, Li Y, Qi Q, Xu P, Feng R, Palmer L, Chen J, Wu R, Yee T, Zhang J, Yao Y, Sharma A, Hardison RC, Weiss MJ, Cheng Y. Single-nucleotide-level mapping of DNA regulatory elements that control fetal hemoglobin expression. Nature Genetics. PMID 33958780 DOI: 10.1038/s41588-021-00861-8  0.484
2021 Keller CA, Wixom AQ, Heuston EF, Giardine B, Hsiung CC, Long MR, Miller A, Anderson SM, Cockburn A, Blobel GA, Bodine DM, Hardison RC. Effects of sheared chromatin length on ChIP-seq quality and sensitivity. G3 (Bethesda, Md.). PMID 33788948 DOI: 10.1093/g3journal/jkab101  0.681
2021 Olson TL, Cheon H, Xing JC, Olson KC, Paila U, Hamele CE, Neelamraju Y, Shemo BC, Schmachtenberg MW, Sundararaman SK, Toro MF, Keller CA, Farber EA, Onengut-Gumuscu S, Garrett-Bakelman FE, ... Hardison RC, et al. Frequent Somatic TET2 Mutations in Chronic NK-LGL Leukemia with Distinct Patterns of Cytopenias. Blood. PMID 33786584 DOI: 10.1182/blood.2020005831  0.611
2021 Luan J, Xiang G, Gómez-García PA, Tome JM, Zhang Z, Vermunt MW, Zhang H, Huang A, Keller CA, Giardine BM, Zhang Y, Lan Y, Lis JT, Lakadamyali M, Hardison RC, et al. Distinct properties and functions of CTCF revealed by a rapidly inducible degron system. Cell Reports. 34: 108783. PMID 33626344 DOI: 10.1016/j.celrep.2021.108783  0.717
2020 Qi Q, Cheng L, Tang X, He Y, Li Y, Yee T, Shrestha D, Feng R, Xu P, Zhou X, Pruett-Miller SM, Hardison RC, Weiss MJ, Cheng Y. Dynamic CTCF binding directly mediates interactions among cis-regulatory elements essential for hematopoiesis. Blood. PMID 33512425 DOI: 10.1182/blood.2020005780  0.482
2020 Lan X, Ren R, Feng R, Ly LC, Lan Y, Zhang Z, Aboreden N, Qin K, Horton JR, Grevet JD, Mayuranathan T, Abdulmalik O, Keller CA, Giardine B, Hardison RC, et al. ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression. Molecular Cell. PMID 33301730 DOI: 10.1016/j.molcel.2020.11.006  0.724
2020 Yang H, Luan Y, Liu T, Lee HJ, Fang L, Wang Y, Wang X, Zhang B, Jin Q, Ang KC, Xing X, Wang J, Xu J, Song F, Sriranga I, ... ... Hardison RC, et al. A map of cis-regulatory elements and 3D genome structures in zebrafish. Nature. PMID 33239788 DOI: 10.1038/s41586-020-2962-9  0.398
2020 Peslak SA, Khandros E, Huang P, Lan X, Geronimo CL, Grevet JD, Abdulmalik O, Zhang Z, Giardine BM, Keller CA, Shi J, Hardison RC, Blobel GA. HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation. Blood Advances. 4: 4560-4572. PMID 32956454 DOI: 10.1182/Bloodadvances.2020002475  0.656
2020 Zhang D, Huang P, Sharma M, Keller CA, Giardine B, Zhang H, Gilgenast TG, Phillips-Cremins JE, Hardison RC, Blobel GA. Alteration of genome folding via contact domain boundary insertion. Nature Genetics. PMID 32868908 DOI: 10.1038/S41588-020-0680-8  0.693
2020 Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, ... ... Hardison RC, et al. Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature. 583: 699-710. PMID 32728249 DOI: 10.1038/S41586-020-2493-4  0.839
2020 Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, et al. Perspectives on ENCODE. Nature. 583: 693-698. PMID 32728248 DOI: 10.1038/S41586-020-2449-8  0.797
2020 He P, Williams BA, Trout D, Marinov GK, Amrhein H, Berghella L, Goh ST, Plajzer-Frick I, Afzal V, Pennacchio LA, Dickel DE, Visel A, Ren B, Hardison RC, Zhang Y, et al. The changing mouse embryo transcriptome at whole tissue and single-cell resolution. Nature. 583: 760-767. PMID 32728245 DOI: 10.1038/S41586-020-2536-X  0.593
2020 Hardison RC. A Cambrian origin for globin gene regulation. Blood. 136: 261-262. PMID 32673391 DOI: 10.1182/Blood.2020006649  0.401
2020 Huang P, Peslak SA, Lan X, Khandros E, Yano JA, Sharma M, Keller CA, Giardine BM, Qin K, Abdulmalik O, Hardison R, Shi J, Blobel GA. HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression. Blood. PMID 32299090 DOI: 10.1182/Blood.2020005301  0.727
2020 Khandros E, Huang P, Peslak SA, Sharma M, Abdulmalik O, Giardine BM, Zhang Z, Keller CA, Hardison R, Blobel GA. Understanding Heterogeneity of Fetal Hemoglobin Induction through Comparative Analysis of F- and A-erythroblasts. Blood. PMID 32268371 DOI: 10.1182/Blood.2020005058  0.678
2020 Xiang G, Keller CA, Heuston EF, Giardine BM, An L, Wixom AQ, Miller A, Cockburn A, Sauria MEG, Weaver K, Lichtenberg J, Göttgens B, Li Q, Bodine D, Mahony S, ... ... Hardison RC, et al. An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis. Genome Research. PMID 32132109 DOI: 10.1101/Gr.255760.119  0.754
2020 Xiang G, Keller CA, Giardine B, An L, Li Q, Zhang Y, Hardison RC. S3norm: simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data. Nucleic Acids Research. PMID 32086521 DOI: 10.1093/Nar/Gkaa105  0.67
2019 An L, Yang T, Yang J, Nuebler J, Xiang G, Hardison RC, Li Q, Zhang Y. OnTAD: hierarchical domain structure reveals the divergence of activity among TADs and boundaries. Genome Biology. 20: 282. PMID 31847870 DOI: 10.1186/S13059-019-1893-Y  0.359
2019 Zhang H, Emerson DJ, Gilgenast TG, Titus KR, Lan Y, Huang P, Zhang D, Wang H, Keller CA, Giardine B, Hardison RC, Phillips-Cremins JE, Blobel GA. Chromatin structure dynamics during the mitosis-to-G1 phase transition. Nature. PMID 31776509 DOI: 10.1038/S41586-019-1778-Y  0.686
2019 Hardison RC, Zhang Y, Keller CA, Xiang G, Heuston EF, An L, Lichtenberg J, Giardine BM, Bodine D, Mahony S, Li Q, Yue F, Weiss MJ, Blobel GA, Taylor J, et al. Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells. Iubmb Life. PMID 31769130 DOI: 10.1002/Iub.2195  0.743
2019 Lan X, Khandros E, Huang P, Peslak SA, Bhardwaj SK, Grevet JD, Abdulmalik O, Wang H, Keller CA, Giardine B, Baeza J, Duffner ER, El Demerdash O, Wu XS, Vakoc CR, ... ... Hardison RC, et al. The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. Blood Advances. 3: 1586-1597. PMID 31126914 DOI: 10.1182/Bloodadvances.2019032318  0.681
2019 Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA. Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription. Cell Reports. 27: 400-415.e5. PMID 30970245 DOI: 10.1016/J.Celrep.2019.03.057  0.72
2019 Peslak SA, Lan X, Khandros E, Huang P, Yano JA, Grevet JD, Abdulmalik O, Keller CA, Hardison RC, Shi J, Blobel GA. Heme-Regulated Inhibitor (HRI) Depletion Cooperates with Pharmacologic Inducers to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation Blood. 134: 3557-3557. DOI: 10.1182/Blood-2019-125664  0.664
2019 Khandros E, Huang P, Peslak SA, Giardine B, Zhang Z, Keller CA, Hardison RC, Blobel GA. Understanding Heterogeneity of Fetal Hemoglobin Induction through Comparative Analysis of Stage-Matched F- and a-Cells Blood. 134: 981-981. DOI: 10.1182/Blood-2019-124099  0.688
2019 Huang P, Peslak SA, Lan X, Khandros E, Sharma M, Qin K, Keller CA, Giardine B, Shi J, Hardison RC, Blobel GA. Heme-Regulated Inhibitor (HRI) Activates Transcription Factor ATF4 to Promote BCL11A Transcription and Fetal Hemoglobin Silencing Blood. 134: 814-814. DOI: 10.1182/Blood-2019-123837  0.746
2019 Heuston EF, Psaila B, Keller CA, SequencingProgram NC, Anderson SM, Kirby M, Murphy LC, Wixom AQ, Giardine B, Hardison RC, Bodine DM. Mouse Erythroid Cells Originate from a Megakaryocyte Precursor in Common Myeloid Progenitors Blood. 134: 337-337. DOI: 10.1182/Blood-2019-121631  0.66
2018 Bartman CR, Hamagami N, Keller CA, Giardine B, Hardison RC, Blobel GA, Raj A. Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation. Molecular Cell. PMID 30554946 DOI: 10.1016/J.Molcel.2018.11.004  0.692
2018 Wang Y, Song F, Zhang B, Zhang L, Xu J, Kuang D, Li D, Choudhary MNK, Li Y, Hu M, Hardison R, Wang T, Yue F. The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions. Genome Biology. 19: 151. PMID 30286773 DOI: 10.1186/S13059-018-1519-9  0.365
2018 Dixon JR, Xu J, Dileep V, Zhan Y, Song F, Le VT, Yardımcı GG, Chakraborty A, Bann DV, Wang Y, Clark R, Zhang L, Yang H, Liu T, Iyyanki S, ... ... Hardison RC, et al. Integrative detection and analysis of structural variation in cancer genomes. Nature Genetics. PMID 30202056 DOI: 10.1038/S41588-018-0195-8  0.407
2018 Grevet JD, Lan X, Hamagami N, Edwards CR, Sankaranarayanan L, Ji X, Bhardwaj SK, Face CJ, Posocco DF, Abdulmalik O, Keller CA, Giardine B, Sidoli S, Garcia BA, Chou ST, ... ... Hardison RC, et al. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells. Science (New York, N.Y.). 361: 285-290. PMID 30026227 DOI: 10.1126/Science.Aao0932  0.672
2018 Heuston EF, Keller CA, Lichtenberg J, Giardine B, Anderson SM, Hardison RC, Bodine DM. Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points. Epigenetics & Chromatin. 11: 22. PMID 29807547 DOI: 10.1186/S13072-018-0195-Z  0.709
2018 Behera V, Evans P, Face CJ, Hamagami N, Sankaranarayanan L, Keller CA, Giardine B, Tan K, Hardison RC, Shi J, Blobel GA. Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility. Nature Communications. 9: 782. PMID 29472540 DOI: 10.1038/S41467-018-03082-6  0.723
2018 Lan X, Khandros E, Grevet JD, Peslak SA, Bhardwaj S, Keller CA, Giardine B, Garcia BA, Hardison RC, Shi J, Blobel GA. Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein SPOP as a Novel Repressor of Fetal Hemoglobin Blood. 132: 414-414. DOI: 10.1182/Blood-2018-99-119518  0.686
2017 Oudelaar AM, Hanssen LLP, Hardison RC, Kassouf MT, Hughes JR, Higgs DR. Between form and function: the complexity of genome folding. Human Molecular Genetics. 26: R208-R215. PMID 28977451 DOI: 10.1093/Hmg/Ddx306  0.431
2017 Zhang Y, Hardison RC. Accurate and reproducible functional maps in 127 human cell types via 2D genome segmentation. Nucleic Acids Research. 45: 9823-9836. PMID 28973456 DOI: 10.1093/Nar/Gkx659  0.364
2017 Huang P, Keller CA, Giardine B, Grevet JD, Davies JOJ, Hughes JR, Kurita R, Nakamura Y, Hardison RC, Blobel GA. Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element. Genes & Development. PMID 28916711 DOI: 10.1101/Gad.303461.117  0.725
2017 Philipsen S, Hardison RC. Evolution of hemoglobin loci and their regulatory elements. Blood Cells, Molecules & Diseases. PMID 28811072 DOI: 10.1016/J.Bcmd.2017.08.001  0.474
2017 Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA. The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Molecular Cell. 66: 102-116.e7. PMID 28388437 DOI: 10.1016/J.Molcel.2017.02.027  0.722
2017 Grevet JD, Hamagami N, Lan X, Sankaranarayanan L, Bhardwaj S, Face C, Posocco D, Abdulmalik O, Keller CA, Giardine B, Sidoli S, Garcia B, Chou ST, Hardison RC, Vakoc C, et al. Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells Blood. 130: 536-536. DOI: 10.1182/Blood.V130.Suppl_1.536.536  0.7
2016 Traxler EA, Yao Y, Wang YD, Woodard KJ, Kurita R, Nakamura Y, Hughes JR, Hardison RC, Blobel GA, Li C, Weiss MJ. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition. Nature Medicine. PMID 27525524 DOI: 10.1038/Nm.4170  0.379
2016 Hardison RC. A guide to translation of research results from model organisms to human. Genome Biology. 17: 161. PMID 27459999 DOI: 10.1186/S13059-016-1026-9  0.319
2016 Hsiung CC, Bartman CR, Huang P, Ginart P, Stonestrom AJ, Keller CA, Face C, Jahn KS, Evans P, Sankaranarayanan L, Giardine B, Hardison RC, Raj A, Blobel GA. A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition. Genes & Development. 30: 1423-39. PMID 27340175 DOI: 10.1101/Gad.280859.116  0.707
2016 Zhang Y, An L, Yue F, Hardison RC. Jointly characterizing epigenetic dynamics across multiple human cell types. Nucleic Acids Research. PMID 27095202 DOI: 10.1093/Nar/Gkw278  0.443
2016 Paralkar VR, Taborda CC, Huang P, Yao Y, Kossenkov AV, Prasad R, Luan J, Davies JO, Hughes JR, Hardison RC, Blobel GA, Weiss MJ. Unlinking an lncRNA from Its Associated cis Element. Molecular Cell. PMID 27041223 DOI: 10.1016/J.Molcel.2016.02.029  0.461
2016 Hardison RC. Finding partners to play the music of regulation. Blood. 127: 1624-6. PMID 27034416 DOI: 10.1182/Blood-2016-02-697169  0.459
2016 Lichtenberg J, Heuston EF, Anderson SM, Sequencing Center NI, Keller CA, Hardison RC, Bodine DM. De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis Blood. 128: 3868-3868. DOI: 10.1182/Blood.V128.22.3868.3868  0.69
2016 Heuston EF, Keller CA, Lichtenberg J, Anderson SM, Sequencing Center NI, Hardison RC, Bodine DM. Establishment of Enhancer Elements during Erythro-Megakaryopoiesis Blood. 128: 1486-1486. DOI: 10.1182/Blood.V128.22.1486.1486  0.73
2016 Hsu SC, Bartman C, Stonestrom AJ, Edwards CR, Gilgenast T, Emerson D, Huang P, Werner MT, Jahn K, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA. The BET Protein BRD2 Cooperates with CTCF to Enforce a Transcriptional Boundary in Erythroid Cells Blood. 128: 1034-1034. DOI: 10.1182/Blood.V128.22.1034.1034  0.731
2015 Lichtenberg J, Heuston EF, Mishra T, Keller CA, Hardison RC, Bodine DM. SBR-Blood: systems biology repository for hematopoietic cells. Nucleic Acids Research. PMID 26590403 DOI: 10.1093/Nar/Gkv1263  0.811
2015 Han GC, Vinayachandran V, Bataille AR, Park B, Chan-Salis KY, Keller CA, Long M, Mahony S, Hardison RC, Pugh BF. Genome-wide organization of GATA1 and TAL1 determined at high resolution. Molecular and Cellular Biology. PMID 26503782 DOI: 10.1128/Mcb.00806-15  0.75
2015 Dogan N, Wu W, Morrissey CS, Chen KB, Stonestrom A, Long M, Keller CA, Cheng Y, Jain D, Visel A, Pennacchio LA, Weiss MJ, Blobel GA, Hardison RC. Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility. Epigenetics & Chromatin. 8: 16. PMID 25984238 DOI: 10.1186/S13072-015-0009-5  0.814
2015 Denas O, Sandstrom R, Cheng Y, Beal K, Herrero J, Hardison RC, Taylor J. Genome-wide comparative analysis reveals human-mouse regulatory landscape and evolution. Bmc Genomics. 16: 87. PMID 25765714 DOI: 10.1186/S12864-015-1245-6  0.62
2015 Makova KD, Hardison RC. The effects of chromatin organization on variation in mutation rates in the genome. Nature Reviews. Genetics. 16: 213-23. PMID 25732611 DOI: 10.1038/Nrg3890  0.345
2015 Jain D, Mishra T, Giardine BM, Keller CA, Morrissey CS, Magargee S, Dorman CM, Long M, Weiss MJ, Hardison RC. Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system. Genomics Data. 4: 1-7. PMID 25729644 DOI: 10.1016/J.Gdata.2015.01.008  0.808
2015 Stonestrom AJ, Hsu SC, Jahn KS, Huang P, Keller CA, Giardine BM, Kadauke S, Campbell AE, Evans P, Hardison RC, Blobel GA. Functions of BET proteins in erythroid gene expression. Blood. 125: 2825-34. PMID 25696920 DOI: 10.1182/Blood-2014-10-607309  0.739
2015 Byrska-Bishop M, VanDorn D, Campbell AE, Betensky M, Arca PR, Yao Y, Gadue P, Costa FF, Nemiroff RL, Blobel GA, French DL, Hardison RC, Weiss MJ, Chou ST. Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus. The Journal of Clinical Investigation. 125: 993-1005. PMID 25621499 DOI: 10.1172/Jci75714  0.807
2015 Hsiung CC, Morrissey CS, Udugama M, Frank CL, Keller CA, Baek S, Giardine B, Crawford GE, Sung MH, Hardison RC, Blobel GA. Genome accessibility is widely preserved and locally modulated during mitosis. Genome Research. 25: 213-25. PMID 25373146 DOI: 10.1101/Gr.180646.114  0.825
2015 Blobel GA, Hsiung CC, Huang P, Keller C, Ginart P, Jahn K, Bartman C, Stonestrom AJ, Evans P, Giardine B, Hardison RC, Raj A. A Hyperactive Transcriptional State Marks Genome Reactivation during Mitotic Exit Blood. 126: 48-48. DOI: 10.1182/Blood.V126.23.48.48  0.755
2015 Heuston EF, Keller CA, Anderson SM, Sequencing Center NI, Hardison RC, Bodine DM. Enhancer Accessibility during Erythropoiesis and Megakaryopoiesis Correlates with Lineage-Specific Gene Expression Blood. 126: 3576-3576. DOI: 10.1182/Blood.V126.23.3576.3576  0.716
2015 Lichtenberg J, Heuston EF, Keller CA, Hardison RC, Bodine DM. Comparison of Expression and Epigenetic Profiles in Human and Mouse Erythropoiesis and Megakaryopoiesis Using a Systems Biology Model Blood. 126: 2383-2383. DOI: 10.1182/Blood.V126.23.2383.2383  0.744
2015 Paralkar VR, Taborda C, Yao Y, Prasad R, Luan J, Hardison RC, Blobel GA, Weiss MJ. A Novel Regulatory Region of the p27 Locus Is Required for Normal Erythroid p27 Expression, and Produces a Long Noncoding RNA with No Detectable Function Blood. 126: 1175-1175. DOI: 10.1182/Blood.V126.23.1175.1175  0.517
2015 Steinberg Shemer O, Byrska-Bishop M, Ulirsch JC, Abdulmalik O, Yao Y, Kim AR, Gadue P, Kingsley PD, French D, Hardison RC, Palis J, Sankaran VG, Weiss MJ. Temporally Distinct Developmental Waves of Erythropoiesis from Human Pluripotent Stem Cells Blood. 126: 1170-1170. DOI: 10.1182/Blood.V126.23.1170.1170  0.789
2014 Chen KB, Hardison R, Zhang Y. dCaP: detecting differential binding events in multiple conditions and proteins. Bmc Genomics. 15: S12. PMID 25522020 DOI: 10.1186/1471-2164-15-S9-S12  0.323
2014 Pope BD, Ryba T, Dileep V, Yue F, Wu W, Denas O, Vera DL, Wang Y, Hansen RS, Canfield TK, Thurman RE, Cheng Y, Gülsoy G, Dennis JH, Snyder MP, ... ... Hardison RC, et al. Topologically associating domains are stable units of replication-timing regulation. Nature. 515: 402-5. PMID 25409831 DOI: 10.1038/Nature13986  0.694
2014 Cheng Y, Ma Z, Kim BH, Wu W, Cayting P, Boyle AP, Sundaram V, Xing X, Dogan N, Li J, Euskirchen G, Lin S, Lin Y, Visel A, Kawli T, ... ... Hardison RC, et al. Principles of regulatory information conservation between mouse and human. Nature. 515: 371-5. PMID 25409826 DOI: 10.1038/Nature13985  0.858
2014 Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, ... ... Hardison RC, et al. A comparative encyclopedia of DNA elements in the mouse genome. Nature. 515: 355-64. PMID 25409824 DOI: 10.1038/Nature13992  0.843
2014 Pimkin M, Kossenkov AV, Mishra T, Morrissey CS, Wu W, Keller CA, Blobel GA, Lee D, Beer MA, Hardison RC, Weiss MJ. Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis. Genome Research. 24: 1932-44. PMID 25319996 DOI: 10.1101/Gr.164178.113  0.827
2014 Wu W, Morrissey CS, Keller CA, Mishra T, Pimkin M, Blobel GA, Weiss MJ, Hardison RC. Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis. Genome Research. 24: 1945-62. PMID 25319994 DOI: 10.1101/Gr.164830.113  0.832
2014 Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, ... ... Hardison RC, et al. Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. Proceedings of the National Academy of Sciences of the United States of America. 111: E3366. PMID 25275169 DOI: 10.1073/Pnas.1410434111  0.759
2014 Chang GS, Chen XA, Park B, Rhee HS, Li P, Han KH, Mishra T, Chan-Salis KY, Li Y, Hardison RC, Wang Y, Pugh BF. A comprehensive and high-resolution genome-wide response of p53 to stress. Cell Reports. 8: 514-27. PMID 25043190 DOI: 10.1016/J.Celrep.2014.06.030  0.748
2014 Hardison RC. Discovering enhancers directly by activity. Nature Methods. 11: 491-2. PMID 24781321 DOI: 10.1038/Nmeth.2933  0.545
2014 Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, ... ... Hardison RC, et al. Defining functional DNA elements in the human genome. Proceedings of the National Academy of Sciences of the United States of America. 111: 6131-8. PMID 24753594 DOI: 10.1073/Pnas.1318948111  0.808
2014 Lee Y, Ghosh D, Hardison RC, Zhang Y. MRHMMs: multivariate regression hidden Markov models and the variantS. Bioinformatics (Oxford, England). 30: 1755-6. PMID 24558116 DOI: 10.1093/Bioinformatics/Btu070  0.449
2014 Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov AV, Anderson SM, Dunagin M, Pimkin M, Gore M, Sun D, Konuthula N, Raj A, An X, Mohandas N, Bodine DM, ... Hardison RC, et al. Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood. 123: 1927-37. PMID 24497530 DOI: 10.1182/Blood-2013-12-544494  0.754
2014 Giardine B, Borg J, Viennas E, Pavlidis C, Moradkhani K, Joly P, Bartsakoulia M, Riemer C, Miller W, Tzimas G, Wajcman H, Hardison RC, Patrinos GP. Updates of the HbVar database of human hemoglobin variants and thalassemia mutations Nucleic Acids Research. 42: D1063-D1069. PMID 24137000 DOI: 10.1093/Nar/Gkt911  0.718
2014 Hsiung CC, Morrissey C, Udugama M, Frank C, Keller CA, Baek S, Giardine B, Crawford GE, Sung M, Raj A, Hardison RC, Blobel GA. Epigenetics of Cellular Memory: Insights from the Chromatin Accessibility Landscape of the Mitotic Genome Blood. 124: 4342-4342. DOI: 10.1182/Blood.V124.21.4342.4342  0.838
2014 Stonestrom AJ, Hsu SC, Jahn KS, Hsuing CC, Huang P, Hardison RC, Blobel GA. Dissection of BET Protein Function in a Hematopoietic Differentiation Model Blood. 124: 1574-1574. DOI: 10.1182/Blood.V124.21.1574.1574  0.431
2013 Zheng R, Rebolledo-Jaramillo B, Zong Y, Wang L, Russo P, Hancock W, Stanger BZ, Hardison RC, Blobel GA. Function of GATA factors in the adult mouse liver. Plos One. 8: e83723. PMID 24367609 DOI: 10.1371/Journal.Pone.0083723  0.354
2013 Mortazavi A, Pepke S, Jansen C, Marinov GK, Ernst J, Kellis M, Hardison RC, Myers RM, Wold BJ. Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps. Genome Research. 23: 2136-48. PMID 24170599 DOI: 10.1101/Gr.158261.113  0.588
2013 Hardison RC, Blobel GA. Genetics. GWAS to therapy by genome edits? Science (New York, N.Y.). 342: 206-7. PMID 24115432 DOI: 10.1126/Science.1245813  0.417
2013 Blobel GA, Hardison RC. A cluster to remember. Cell. 154: 718-20. PMID 23953105 DOI: 10.1016/J.Cell.2013.07.041  0.31
2013 Su MY, Steiner LA, Bogardus H, Mishra T, Schulz VP, Hardison RC, Gallagher PG. Identification of biologically relevant enhancers in human erythroid cells. The Journal of Biological Chemistry. 288: 8433-44. PMID 23341446 DOI: 10.1074/Jbc.M112.413260  0.806
2013 Hoffman MM, Ernst J, Wilder SP, Kundaje A, Harris RS, Libbrecht M, Giardine B, Ellenbogen PM, Bilmes JA, Birney E, Hardison RC, Dunham I, Kellis M, Noble WS. Integrative annotation of chromatin elements from ENCODE data. Nucleic Acids Research. 41: 827-41. PMID 23221638 DOI: 10.1093/Nar/Gks1284  0.46
2013 Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov A, Konuthula N, An X, Narla M, Bodine DM, Hardison RC, Weiss MJ. Species-Specific Functions For Long Noncoding RNAs During Erythropoeisis Blood. 122: 2441-2441. DOI: 10.1182/Blood.V122.21.2441.2441  0.775
2013 Heuston EF, Lichtenberg J, Anderson SM, Paralkar VR, Capone CK, Hardison RC, Weiss MJ, Bodine DM. Differences In The Genome-Wide Epigenetic Signatures Of mRNA and Long Non-Coding RNA Genes In Mouse Erythroblasts and Megakaryocytes Blood. 122: 1198-1198. DOI: 10.1182/Blood.V122.21.1198.1198  0.457
2012 Hardison RC. Evolution of hemoglobin and its genes. Cold Spring Harbor Perspectives in Medicine. 2: a011627. PMID 23209182 DOI: 10.1101/Cshperspect.A011627  0.434
2012 Chou ST, Byrska-Bishop M, Tober JM, Yao Y, Vandorn D, Opalinska JB, Mills JA, Choi JK, Speck NA, Gadue P, Hardison RC, Nemiroff RL, French DL, Weiss MJ. Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 17573-8. PMID 23045704 DOI: 10.1073/Pnas.1211175109  0.77
2012 Hardison RC. Genome-wide epigenetic data facilitate understanding of disease susceptibility association studies. The Journal of Biological Chemistry. 287: 30932-40. PMID 22952232 DOI: 10.1074/Jbc.R112.352427  0.401
2012 Kadauke S, Udugama MI, Pawlicki JM, Achtman JC, Jain DP, Cheng Y, Hardison RC, Blobel GA. Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell. 150: 725-37. PMID 22901805 DOI: 10.1016/J.Cell.2012.06.038  0.728
2012 Stamatoyannopoulos JA, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert DM, Groudine M, Bender M, Kaul R, Canfield T, Giste E, Johnson A, Zhang M, Balasundaram G, et al. An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biology. 13: 418. PMID 22889292 DOI: 10.1186/Gb-2012-13-8-418  0.798
2012 Hardison RC, Taylor J. Genomic approaches towards finding cis-regulatory modules in animals. Nature Reviews. Genetics. 13: 469-83. PMID 22705667 DOI: 10.1038/Nrg3242  0.498
2012 Song G, Riemer C, Dickins B, Kim HL, Zhang L, Zhang Y, Hsu CH, Hardison RC, Nisc Comparative Sequencing Program, Green ED, Miller W. Revealing mammalian evolutionary relationships by comparative analysis of gene clusters. Genome Biology and Evolution. 4: 586-601. PMID 22454131 DOI: 10.1093/Gbe/Evs032  0.765
2012 Kadauke S, Campbell AE, Stonestrom AJ, Jain DP, Hardison RC, Blobel GA. GATA1 and the BET Family Protein Brd3 Form a Mitotic Bookmarking Complex Blood. 120: 282-282. DOI: 10.1182/Blood.V120.21.282.282  0.44
2012 Paralkar VR, Mishra T, Luan J, Yao Y, Konuthula N, Bodine DM, Hardison RC, Weiss MJ. Long Noncoding RNAs in Erythropoiesis and Megakaryopoiesis. Blood. 120: 2331-2331. DOI: 10.1182/Blood.V120.21.2331.2331  0.771
2011 Pilon AM, Ajay SS, Kumar SA, Steiner LA, Cherukuri PF, Wincovitch S, Anderson SM, Mullikin JC, Gallagher PG, Hardison RC, Margulies EH, Bodine DM. Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation. Blood. 118: e139-48. PMID 21900194 DOI: 10.1182/Blood-2011-05-355107  0.659
2011 Ponting CP, Hardison RC. What fraction of the human genome is functional? Genome Research. 21: 1769-76. PMID 21875934 DOI: 10.1101/Gr.116814.110  0.425
2011 Song G, Hsu CH, Riemer C, Zhang Y, Kim HL, Hoffmann F, Zhang L, Hardison RC, Green ED, Miller W. Conversion events in gene clusters. Bmc Evolutionary Biology. 11: 226. PMID 21798034 DOI: 10.1186/1471-2148-11-226  0.744
2011 Wu W, Cheng Y, Keller CA, Ernst J, Kumar SA, Mishra T, Morrissey C, Dorman CM, Chen KB, Drautz D, Giardine B, Shibata Y, Song L, Pimkin M, Crawford GE, ... ... Hardison RC, et al. Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Research. 21: 1659-71. PMID 21795386 DOI: 10.1101/Gr.125088.111  0.82
2011 Lamonica JM, Deng W, Kadauke S, Campbell AE, Gamsjaeger R, Wang H, Cheng Y, Billin AN, Hardison RC, Mackay JP, Blobel GA. Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proceedings of the National Academy of Sciences of the United States of America. 108: E159-68. PMID 21536911 DOI: 10.1073/Pnas.1102140108  0.583
2011 Giardine B, Borg J, Higgs DR, Peterson KR, Philipsen S, Maglott D, Singleton BK, Anstee DJ, Basak AN, Clark B, Costa FC, Faustino P, Fedosyuk H, Felice AE, Francina A, ... ... Hardison RC, et al. Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach. Nature Genetics. 43: 295-301. PMID 21423179 DOI: 10.1038/Ng.785  0.709
2011 Kadauke S, Pawlicki JM, Udugama M, Achtman JC, Cheng Y, Hardison RC, Blobel GA. Lineage-Specific Mitotic Bookmarking by Hematopoietic Transcription Factor GATA1 Blood. 118: 547-547. DOI: 10.1182/Blood.V118.21.547.547  0.598
2010 Hsu CH, Zhang Y, Hardison RC, Green ED, Miller W. An effective method for detecting gene conversion events in whole genomes. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 17: 1281-97. PMID 20874409 DOI: 10.1089/Cmb.2010.0103  0.492
2010 Hardison RC. Variable evolutionary signatures at the heart of enhancers. Nature Genetics. 42: 734-5. PMID 20802475 DOI: 10.1038/Ng0910-734  0.409
2010 Elnitski L, Burhans R, Riemer C, Hardison R, Miller W. MultiPipMaker: a comparative alignment server for multiple DNA sequences. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit10.4. PMID 20521245 DOI: 10.1002/0471250953.bi1004s30  0.81
2010 Schuster SC, Miller W, Ratan A, Tomsho LP, Giardine B, Kasson LR, Harris RS, Petersen DC, Zhao F, Qi J, Alkan C, Kidd JM, Sun Y, Drautz DI, Bouffard P, ... ... Hardison RC, et al. Complete Khoisan and Bantu genomes from southern Africa. Nature. 463: 943-7. PMID 20164927 DOI: 10.1038/Nature08795  0.759
2009 Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB. Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Molecular Cell. 36: 682-95. PMID 19941827 DOI: 10.1016/J.Molcel.2009.11.002  0.61
2009 Cheng Y, Wu W, Kumar SA, Yu D, Deng W, Tripic T, King DC, Chen KB, Zhang Y, Drautz D, Giardine B, Schuster SC, Miller W, Chiaromonte F, Zhang Y, ... ... Hardison RC, et al. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Research. 19: 2172-84. PMID 19887574 DOI: 10.1101/Gr.098921.109  0.843
2009 Zhang Y, Wu W, Cheng Y, King DC, Harris RS, Taylor J, Chiaromonte F, Hardison RC. Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1. Nucleic Acids Research. 37: 7024-38. PMID 19767611 DOI: 10.1093/Nar/Gkp747  0.775
2009 Hardison RC. It takes (LMO) 2 to tango. Blood. 113: 5693. PMID 19498023 DOI: 10.1182/Blood-2009-03-207258  0.343
2009 Chou ST, Khandros E, Bailey LC, Nichols KE, Vakoc CR, Yao Y, Huang Z, Crispino JD, Hardison RC, Blobel GA, Weiss MJ. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood. 114: 983-94. PMID 19491391 DOI: 10.1182/Blood-2009-03-207944  0.433
2009 Kaput J, Cotton RG, Hardman L, Watson M, Al Aqeel AI, Al-Aama JY, Al-Mulla F, Alonso S, Aretz S, Auerbach AD, Bapat B, Bernstein IT, Bhak J, Bleoo SL, Blöcker H, ... ... Hardison R, et al. Planning the human variome project: the Spain report. Human Mutation. 30: 496-510. PMID 19306394 DOI: 10.1002/Humu.20972  0.366
2009 den Dunnen JT, Sijmons RH, Andersen PS, Vihinen M, Beckmann JS, Rossetti S, Talbot CC, Hardison RC, Povey S, Cotton RG. Sharing data between LSDBs and central repositories. Human Mutation. 30: 493-5. PMID 19306393 DOI: 10.1002/Humu.20977  0.329
2009 Tripic T, Deng W, Cheng Y, Zhang Y, Vakoc CR, Gregory GD, Hardison RC, Blobel GA. SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood. 113: 2191-201. PMID 19011221 DOI: 10.1182/Blood-2008-07-169417  0.578
2009 Forget BG, Hardison RC. The normal structure and regulation of human globin gene clusters Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management, Second Edition. 46-61. DOI: 10.1017/CBO9780511596582.007  0.349
2009 Hou M, Riemer C, Berman P, Hardison RC, Miller W. Aligning two genomic sequences that contain duplications Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5817: 98-110. DOI: 10.1007/978-3-642-04744-2_9  0.741
2008 Hardison RC. Globin genes on the move. Journal of Biology. 7: 35. PMID 19040770 DOI: 10.1186/Jbiol92  0.383
2008 Cheng Y, King DC, Dore LC, Zhang X, Zhou Y, Zhang Y, Dorman C, Abebe D, Kumar SA, Chiaromonte F, Miller W, Green RD, Weiss MJ, Hardison RC. Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif. Genome Research. 18: 1896-905. PMID 18818370 DOI: 10.1101/Gr.083089.108  0.826
2008 dos Santos CO, Dore LC, Valentine E, Shelat SG, Hardison RC, Ghosh M, Wang W, Eisenstein RS, Costa FF, Weiss MJ. An iron responsive element-like stem-loop regulates alpha-hemoglobin-stabilizing protein mRNA. The Journal of Biological Chemistry. 283: 26956-64. PMID 18676996 DOI: 10.1074/Jbc.M802421200  0.324
2008 Warren WC, Hillier LW, Marshall Graves JA, Birney E, Ponting CP, Grützner F, Belov K, Miller W, Clarke L, Chinwalla AT, Yang SP, Heger A, Locke DP, Miethke P, Waters PD, ... ... Hardison R, et al. Genome analysis of the platypus reveals unique signatures of evolution. Nature. 453: 175-83. PMID 18464734 DOI: 10.1038/Nature06936  0.437
2008 Tyekucheva S, Makova KD, Karro JE, Hardison RC, Miller W, Chiaromonte F. Human-macaque comparisons illuminate variation in neutral substitution rates. Genome Biology. 9: R76. PMID 18447906 DOI: 10.1186/Gb-2008-9-4-R76  0.326
2008 Chen Z, Luo HY, Basran RK, Hsu TH, Mang DW, Nuntakarn L, Rosenfield CG, Patrinos GP, Hardison RC, Steinberg MH, Chui DH. A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F. Molecular and Cellular Biology. 28: 4386-93. PMID 18443038 DOI: 10.1128/Mcb.00071-08  0.436
2008 Dore LC, Amigo JD, Dos Santos CO, Zhang Z, Gai X, Tobias JW, Yu D, Klein AM, Dorman C, Wu W, Hardison RC, Paw BH, Weiss MJ. A GATA-1-regulated microRNA locus essential for erythropoiesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 3333-8. PMID 18303114 DOI: 10.1073/Pnas.0712312105  0.527
2008 Karro JE, Peifer M, Hardison RC, Kollmann M, von Grünberg HH. Exponential decay of GC content detected by strand-symmetric substitution rates influences the evolution of isochore structure. Molecular Biology and Evolution. 25: 362-74. PMID 18042807 DOI: 10.1093/Molbev/Msm261  0.374
2008 Griffith OL, Montgomery SB, Bernier B, Chu B, Kasaian K, Aerts S, Mahony S, Sleumer MC, Bilenky M, Haeussler M, Griffith M, Gallo SM, Giardine B, Hooghe B, Van Loo P, ... ... Hardison R, et al. ORegAnno: an open-access community-driven resource for regulatory annotation. Nucleic Acids Research. 36: D107-13. PMID 18006570 DOI: 10.1093/Nar/Gkm967  0.461
2008 Chou ST, Bailey C, Yao Y, Huang Z, Nichols K, Crispino J, Hardison R, Blobel G, Vakoc C, Weiss MJ. Graded Repression of PU.1 Expression by GATA Factors Influence Hematopoietic Progenitor Cell Fate Blood. 112: 2469-2469. DOI: 10.1182/Blood.V112.11.2469.2469  0.327
2007 Miller W, Rosenbloom K, Hardison RC, Hou M, Taylor J, Raney B, Burhans R, King DC, Baertsch R, Blankenberg D, Kosakovsky Pond SL, Nekrutenko A, Giardine B, Harris RS, Tyekucheva S, et al. 28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Research. 17: 1797-808. PMID 17984227 DOI: 10.1101/Gr.6761107  0.655
2007 Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, ... ... Hardison RC, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 447: 799-816. PMID 17571346 DOI: 10.1038/Nature05874  0.801
2007 Blankenberg D, Taylor J, Schenck I, He J, Zhang Y, Ghent M, Veeraraghavan N, Albert I, Miller W, Makova KD, Hardison RC, Nekrutenko A. A framework for collaborative analysis of ENCODE data: making large-scale analyses biologist-friendly. Genome Research. 17: 960-4. PMID 17568012 DOI: 10.1101/Gr.5578007  0.478
2007 King DC, Taylor J, Zhang Y, Cheng Y, Lawson HA, Martin J, Chiaromonte F, Miller W, Hardison RC. Finding cis-regulatory elements using comparative genomics: some lessons from ENCODE data. Genome Research. 17: 775-86. PMID 17567996 DOI: 10.1101/Gr.5592107  0.745
2007 Margulies EH, Cooper GM, Asimenos G, Thomas DJ, Dewey CN, Siepel A, Birney E, Keefe D, Schwartz AS, Hou M, Taylor J, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, ... ... Hardison R, et al. Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Research. 17: 760-74. PMID 17567995 DOI: 10.1101/Gr.6034307  0.445
2007 Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER, Remington KA, Strausberg RL, Venter JC, Wilson RK, Batzer MA, Bustamante CD, Eichler EE, Hahn MW, ... Hardison RC, et al. Evolutionary and biomedical insights from the rhesus macaque genome. Science (New York, N.Y.). 316: 222-34. PMID 17431167 DOI: 10.1126/Science.1139247  0.623
2007 Giardine B, Riemer C, Hefferon T, Thomas D, Hsu F, Zielenski J, Sang Y, Elnitski L, Cutting G, Trumbower H, Kern A, Kuhn R, Patrinos GP, Hughes J, Higgs D, ... ... Hardison RC, et al. PhenCode: connecting ENCODE data with mutations and phenotype. Human Mutation. 28: 554-62. PMID 17326095 DOI: 10.1002/Humu.20484  0.822
2007 Giardine B, van Baal S, Kaimakis P, Riemer C, Miller W, Samara M, Kollia P, Anagnou NP, Chui DH, Wajcman H, Hardison RC, Patrinos GP. HbVar database of human hemoglobin variants and thalassemia mutations: 2007 update. Human Mutation. 28: 206. PMID 17221864 DOI: 10.1002/Humu.9479  0.731
2007 Dore LC, dos Santos CO, Amigo J, Dorman C, Wu W, Hardison RC, Paw BH, Weiss MJ. A GATA-1-Regulated microRNA Cluster That Is Essential for Erythropoiesis. Blood. 110: 378-378. DOI: 10.1182/Blood.V110.11.378.378  0.56
2007 Chou ST, Bailey CL, Hardison RC, Blobel GA, Vakoc CR, Weiss MJ. GATA-1 Represses PU.1/Sfpi-1 Gene Transcription in Erythro-Megakaryocytic Progenitors. Blood. 110: 1226-1226. DOI: 10.1182/Blood.V110.11.1226.1226  0.459
2007 Zhou Y, Cheng Y, Wang H, Zhang Y, King DC, Taylor J, Chiaromonte F, Dorman C, Miller W, Dore LC, Weiss MJ, Hardison RC. Validation of predicted erythroid cis-regulatory modules Blood Cells, Molecules, and Diseases. 38: 190. DOI: 10.1016/J.Bcmd.2006.10.158  0.721
2007 Hardison R, Giardine B, Riemer C, Miller W, Chui D, Wajcman H, Patrinos G. HbVar database for human hemoglobin variants and thalassemia mutations Blood Cells, Molecules, and Diseases. 38: 167-168. DOI: 10.1016/J.Bcmd.2006.10.109  0.688
2007 Hardison RC, King DC, Taylor J, Wang H, Zhang Y, Zhou Y, Cheng Y, Dorman C, Dore LC, Weiss MJ, Chiaromonte F, Miller W. Comparative genomics to find function in noncoding DNA Blood Cells, Molecules, and Diseases. 38: 144-145. DOI: 10.1016/J.Bcmd.2006.10.060  0.749
2006 Taylor J, Tyekucheva S, King DC, Hardison RC, Miller W, Chiaromonte F. ESPERR: learning strong and weak signals in genomic sequence alignments to identify functional elements. Genome Research. 16: 1596-604. PMID 17053093 DOI: 10.1101/Gr.4537706  0.618
2006 Wang H, Zhang Y, Cheng Y, Zhou Y, King DC, Taylor J, Chiaromonte F, Kasturi J, Petrykowska H, Gibb B, Dorman C, Miller W, Dore LC, Welch J, Weiss MJ, ... Hardison RC, et al. Experimental validation of predicted mammalian erythroid cis-regulatory modules. Genome Research. 16: 1480-92. PMID 17038566 DOI: 10.1101/Gr.5353806  0.82
2006 Elnitski L, King D, Hardison RC. Computational prediction of cis-regulatory modules from multispecies alignments using Galaxy, Table Browser, and GALA. Methods in Molecular Biology (Clifton, N.J.). 338: 91-103. PMID 16888352 DOI: 10.1385/1-59745-097-9:91  0.789
2005 Elnitski L, Riemer C, Burhans R, Hardison R, Miller W. MultiPipMaker: comparative alignment server for multiple DNA sequences. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit10.4. PMID 18428743 DOI: 10.1002/0471250953.Bi1004S9  0.818
2005 Giardine B, Riemer C, Hardison RC, Burhans R, Elnitski L, Shah P, Zhang Y, Blankenberg D, Albert I, Taylor J, Miller W, Kent WJ, Nekrutenko A. Galaxy: a platform for interactive large-scale genome analysis. Genome Research. 15: 1451-5. PMID 16169926 DOI: 10.1101/Gr.4086505  0.792
2005 King DC, Taylor J, Elnitski L, Chiaromonte F, Miller W, Hardison RC. Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences. Genome Research. 15: 1051-60. PMID 16024817 DOI: 10.1101/Gr.3642605  0.79
2005 Elnitski L, Giardine B, Shah P, Zhang Y, Riemer C, Weirauch M, Burhans R, Miller W, Hardison RC. Improvements to GALA and dbERGE II: databases featuring genomic sequence alignment, annotation and experimental results. Nucleic Acids Research. 33: D466-70. PMID 15608239 DOI: 10.1093/Nar/Gki045  0.839
2005 Ovcharenko I, Loots GG, Nobrega MA, Hardison RC, Miller W, Stubbs L. Evolution and functional classification of vertebrate gene deserts. Genome Research. 15: 137-45. PMID 15590943 DOI: 10.1101/Gr.3015505  0.455
2005 Ovcharenko I, Loots GG, Giardine BM, Hou M, Ma J, Hardison RC, Stubbs L, Miller W. Mulan: multiple-sequence local alignment and visualization for studying function and evolution. Genome Research. 15: 184-94. PMID 15590941 DOI: 10.1101/Gr.3007205  0.495
2005 Dore LC, Vakoc CR, Blobel GA, Hardison RC, Bodine DM, Gallagher PG, Weiss MJ. Genomic Organization, Chromatin Structure, and Transcriptional Regulation of the Murine Alpha Hemoglobin Stabilizing Protein (AHSP) Gene. Blood. 106: 3633-3633. DOI: 10.1182/Blood.V106.11.3633.3633  0.51
2004 Miller W, Makova KD, Nekrutenko A, Hardison RC. Comparative genomics. Annual Review of Genomics and Human Genetics. 5: 15-56. PMID 15485342 DOI: 10.1146/annurev.genom.5.061903.180057  0.316
2004 Welch JJ, Watts JA, Vakoc CR, Yao Y, Wang H, Hardison RC, Blobel GA, Chodosh LA, Weiss MJ. Global regulation of erythroid gene expression by transcription factor GATA-1. Blood. 104: 3136-47. PMID 15297311 DOI: 10.1182/Blood-2004-04-1603  0.506
2004 Kolbe D, Taylor J, Elnitski L, Eswara P, Li J, Miller W, Hardison R, Chiaromonte F. Regulatory potential scores from genome-wide three-way alignments of human, mouse, and rat. Genome Research. 14: 700-7. PMID 15060013 DOI: 10.1101/Gr.1976004  0.687
2004 Tufarelli C, Hardison R, Miller W, Hughes J, Clark K, Ventress N, Frischauf AM, Higgs DR. Comparative analysis of the alpha-like globin clusters in mouse, rat, and human chromosomes indicates a mechanism underlying breaks in conserved synteny. Genome Research. 14: 623-30. PMID 15060003 DOI: 10.1101/Gr.2143604  0.345
2004 Yang S, Smit AF, Schwartz S, Chiaromonte F, Roskin KM, Haussler D, Miller W, Hardison RC. Patterns of insertions and their covariation with substitutions in the rat, mouse, and human genomes. Genome Research. 14: 517-27. PMID 15059992 DOI: 10.1101/Gr.1984404  0.6
2004 Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, ... ... Hardison RC, et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 428: 493-521. PMID 15057822 DOI: 10.1038/Nature02426  0.825
2004 Ovcharenko I, Loots GG, Hardison RC, Miller W, Stubbs L. zPicture: dynamic alignment and visualization tool for analyzing conservation profiles. Genome Research. 14: 472-7. PMID 14993211 DOI: 10.1101/Gr.2129504  0.486
2004 Patrinos GP, Giardine B, Riemer C, Miller W, Chui DH, Anagnou NP, Wajcman H, Hardison RC. Improvements in the HbVar database of human hemoglobin variants and thalassemia mutations for population and sequence variation studies. Nucleic Acids Research. 32: D537-41. PMID 14681476 DOI: 10.1093/Nar/Gkh006  0.738
2003 Elnitski L, Riemer C, Schwartz S, Hardison R, Miller W. PipMaker: a World Wide Web server for genomic sequence alignments. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit 10.2. PMID 18428692 DOI: 10.1002/0471250953.Bi1002S00  0.82
2003 Hardison RC, Chiaromonte F, Kolbe D, Wang H, Petrykowska H, Elnitski L, Yang S, Giardine B, Zhang Y, Riemer C, Schwartz S, Haussler D, Roskin KM, Weber RJ, Diekhans M, et al. Global predictions and tests of erythroid regulatory regions. Cold Spring Harbor Symposia On Quantitative Biology. 68: 335-44. PMID 15338635 DOI: 10.1101/Sqb.2003.68.335  0.77
2003 Bulger M, Schübeler D, Bender MA, Hamilton J, Farrell CM, Hardison RC, Groudine M. A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus. Molecular and Cellular Biology. 23: 5234-44. PMID 12861010 DOI: 10.1128/Mcb.23.15.5234-5244.2003  0.371
2003 Schwartz S, Elnitski L, Li M, Weirauch M, Riemer C, Smit A, Green ED, Hardison RC, Miller W. MultiPipMaker and supporting tools: Alignments and analysis of multiple genomic DNA sequences. Nucleic Acids Research. 31: 3518-24. PMID 12824357 DOI: 10.1093/Nar/Gkg579  0.83
2003 Giardine B, Elnitski L, Riemer C, Makalowska I, Schwartz S, Miller W, Hardison RC. GALA, a database for genomic sequence alignments and annotations. Genome Research. 13: 732-41. PMID 12671007 DOI: 10.1101/Gr.603103  0.844
2003 Schwartz S, Kent WJ, Smit A, Zhang Z, Baertsch R, Hardison RC, Haussler D, Miller W. Human-mouse alignments with BLASTZ. Genome Research. 13: 103-7. PMID 12529312 DOI: 10.1101/Gr.809403  0.419
2003 Elnitski L, Hardison RC, Li J, Yang S, Kolbe D, Eswara P, O'Connor MJ, Schwartz S, Miller W, Chiaromonte F. Distinguishing regulatory DNA from neutral sites. Genome Research. 13: 64-72. PMID 12529307 DOI: 10.1101/Gr.817703  0.783
2003 Hardison RC, Roskin KM, Yang S, Diekhans M, Kent WJ, Weber R, Elnitski L, Li J, O'Connor M, Kolbe D, Schwartz S, Furey TS, Whelan S, Goldman N, Smit A, et al. Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution. Genome Research. 13: 13-26. PMID 12529302 DOI: 10.1101/Gr.844103  0.761
2003 Frazer KA, Elnitski L, Church DM, Dubchak I, Hardison RC. Cross-species sequence comparisons: a review of methods and available resources. Genome Research. 13: 1-12. PMID 12529301 DOI: 10.1101/Gr.222003  0.685
2003 Hardison RC. Fishing for evolutionary clues to globin gene regulation Blood. 101: 2451-2451. DOI: 10.1182/Blood-2003-02-0381  0.474
2002 Elnitski L, Riemer C, Petrykowska H, Florea L, Schwartz S, Miller W, Hardison R. PipTools: a computational toolkit to annotate and analyze pairwise comparisons of genomic sequences. Genomics. 80: 681-90. PMID 12504859 DOI: 10.1006/Geno.2002.7018  0.834
2002 Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, ... ... Hardison RC, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420: 520-62. PMID 12466850 DOI: 10.1038/Nature01262  0.765
2002 Molete JM, Petrykowska H, Sigg M, Miller W, Hardison R. Functional and binding studies of HS3.2 of the beta-globin locus control region. Gene. 283: 185-97. PMID 11867225 DOI: 10.1016/S0378-1119(01)00858-7  0.823
2002 Hardison RC, Chui DH, Giardine B, Riemer C, Patrinos GP, Anagnou N, Miller W, Wajcman H. HbVar: A relational database of human hemoglobin variants and thalassemia mutations at the globin gene server. Human Mutation. 19: 225-33. PMID 11857738 DOI: 10.1002/Humu.10044  0.737
2001 Chiaromonte F, Yang S, Elnitski L, Yap VB, Miller W, Hardison RC. Association between divergence and interspersed repeats in mammalian noncoding genomic DNA Proceedings of the National Academy of Sciences of the United States of America. 98: 14503-14508. PMID 11717405 DOI: 10.1073/Pnas.251423898  0.759
2001 Hardison RC, Chui DHK, Riemer C, Giardine B, Lehväslaiho H, Wajcman H, Miller W. Databases of human hemoglobin variants and other resources at the globin gene server Hemoglobin. 25: 183-193. PMID 11480780 DOI: 10.1081/Hem-100104027  0.742
2001 Molete JM, Petrykowska H, Bouhassira EE, Feng YQ, Miller W, Hardison RC. Sequences flanking hypersensitive sites of the beta-globin locus control region are required for synergistic enhancement. Molecular and Cellular Biology. 21: 2969-80. PMID 11287603 DOI: 10.1128/Mcb.21.9.2969-2980.2001  0.822
2001 Hardison RC. New views of evolution and regulation of vertebrate β-like globin gene clusters from an orphaned gene in marsupials Proceedings of the National Academy of Sciences of the United States of America. 98: 1327-1329. PMID 11171947 DOI: 10.1073/Pnas.98.4.1327  0.397
2001 Tufarelli C, Frischauf AM, Hardison R, Flint J, Higgs DR. Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain. Genomics. 71: 307-14. PMID 11170747 DOI: 10.1006/Geno.2000.6394  0.402
2001 Flint J, Tufarelli C, Peden J, Clark K, Daniels RJ, Hardison R, Miller W, Philipsen S, Tan-Un KC, McMorrow T, Frampton J, Alter BP, Frischauf AM, Higgs DR. Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the α globin cluster Human Molecular Genetics. 10: 371-382. PMID 11157800 DOI: 10.1093/Hmg/10.4.371  0.49
2000 Ikonomi P, Noguchi CT, Miller W, Kassahun H, Hardison R, Schechter AN. Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins Gene. 261: 277-287. PMID 11167015 DOI: 10.1016/S0378-1119(00)00510-2  0.449
2000 Bulger M, Bender MA, van Doorninck JH, Wertman B, Farrell CM, Felsenfeld G, Groudine M, Hardison R. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. Proceedings of the National Academy of Sciences of the United States of America. 97: 14560-5. PMID 11121057 DOI: 10.1073/Pnas.97.26.14560  0.47
2000 Elnitski L, Li J, Noguchi CT, Miller W, Hardison R. A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region. The Journal of Biological Chemistry. 276: 6289-98. PMID 11092897 DOI: 10.1074/Jbc.M009624200  0.701
2000 Hardison RC. Conserved noncoding sequences are reliable guides to regulatory elements Trends in Genetics. 16: 369-372. PMID 10973062 DOI: 10.1016/S0168-9525(00)02081-3  0.46
2000 Schwartz S, Zhang Z, Frazer KA, Smit A, Riemer C, Bouck J, Gibbs R, Hardison R, Miller W. PipMaker - A web server for aligning two genomic DNA sequences Genome Research. 10: 577-586. PMID 10779500 DOI: 10.1101/Gr.10.4.577  0.776
2000 Elnitski L, Hardison R. Efficient and reliable transfection of mouse erythroleukemia cells using cationic lipids. Blood Cells, Molecules & Diseases. 25: 299-304. PMID 10744425 DOI: 10.1006/Bcmd.1999.0257  0.648
2000 Florea L, Li M, Riemer C, Giardine B, Miller W, Hardison R. Validating Computer Programs for Functional Genomics in Gene Regulatory Regions Current Genomics. 1: 11-27. DOI: 10.2174/1389202003351733  0.742
1999 Stojanovic N, Florea L, Riemer C, Gumucio D, Slightom J, Goodman M, Miller W, Hardison R. Comparison of five methods for finding conserved sequences in multiple alignments of gene regulatory regions Nucleic Acids Research. 27: 3899-3910. PMID 10481030 DOI: 10.1093/Nar/27.19.3899  0.763
1998 Riemer C, ElSherbini A, Stojanovic N, Schwartz S, Kwitkin PB, Miller W, Hardison R. A database of experimental results on globin gene expression Genomics. 53: 325-337. PMID 9799599 DOI: 10.1006/Geno.1998.5524  0.765
1998 Hardison RC, Chui DHK, Riemer CR, Miller W, Carver MFH, Molchanova TP, Efremov GD, Huisman THJ. Access to a Syllabus of Human Hemoglobin Variants (1996) via the world wide web Hemoglobin. 22: 113-127. PMID 9576329 DOI: 10.3109/03630269809092136  0.731
1998 Li J, Noguchi CT, Miller W, Hardison R, Schechter AN. Multiple regulatory elements in the 5'-flanking sequence of the human ε-globin gene Journal of Biological Chemistry. 273: 10202-10209. PMID 9553070 DOI: 10.1074/Jbc.273.17.10202  0.514
1998 Hardison R. Hemoglobins from bacteria to man: evolution of different patterns of gene expression. The Journal of Experimental Biology. 201: 1099-117. PMID 9510523  0.433
1998 Hardison R, Riemer C, Chui DHK, Huisman THJ, Miller W. Electronic access to sequence alignments, experimental results, and human mutations as an aid to studying globin gene regulation Genomics. 47: 429-437. PMID 9480762 DOI: 10.1006/Geno.1997.5147  0.745
1998 Bender M, Reik A, Close J, Telling A, Epner E, Fiering S, Hardison R, Groudine M. Description and Targeted Deletion of 5′ Hypersensitive Site 5 and 6 of the Mouse β-Globin Locus Control Region Blood. 92: 4394-4403. DOI: 10.1182/Blood.V92.11.4394.423K48_4394_4403  0.362
1998 Chui DHK, Hardison R, Riemer C, Miller W, Carver MFH, Molchanova TP, Efremov GD, Huisman THJ. An Electronic Database of Human Hemoglobin Variants on the World Wide Web Blood. 91: 2643-2644. DOI: 10.1182/Blood.V91.8.2643.2643_2643_2644  0.697
1997 Hardison R, Slightom JL, Gumucio DL, Goodman M, Stojanovic N, Miller W. Locus control regions of mammalian β-globin gene clusters: Combining phylogenetic analyses and experimental results to gain functional insights Gene. 205: 73-94. PMID 9461381 DOI: 10.1016/S0378-1119(97)00474-5  0.504
1997 Hardison RC, Oeltjen J, Miller W. Long human mouse sequence alignments reveal novel regulatory elements: A reason to sequence the mouse genome Genome Research. 7: 959-966. PMID 9331366 DOI: 10.1101/Gr.7.10.959  0.5
1997 Shewchuk BM, Hardison RC. CpG islands from the α-globin gene cluster increase gene expression in an integration-dependent manner Molecular and Cellular Biology. 17: 5856-5866. PMID 9315643 DOI: 10.1128/Mcb.17.10.5856  0.812
1997 Tang DC, Ebb D, Hardison RC, Rodgers GP. Restoration of the CCAAT box or insertion of the CACCC motif activates [corrected] delta-globin gene expression. Blood. 90: 421-7. PMID 9207479  0.37
1997 Shelton DA, Stegman L, Hardison R, Miller W, Bock JH, Slightom JL, Goodman M, Gumucio DL. Phylogenetic footprinting of hypersensitive site 3 of the beta-globin locus control region. Blood. 89: 3457-69. PMID 9129054  0.324
1997 Slightom JL, Bock JH, Tagle DA, Gumucio DL, Goodman M, Stojanovic N, Jackson J, Miller W, Hardison R. The complete sequences of the galago and rabbit beta-globin locus control regions: extended sequence and functional conservation outside the cores of DNase hypersensitive sites. Genomics. 39: 90-4. PMID 9027490 DOI: 10.1006/Geno.1996.4458  0.465
1997 Elnitski L, Miller W, Hardison R. Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins. The Journal of Biological Chemistry. 272: 369-78. PMID 8995271 DOI: 10.1074/Jbc.272.1.369  0.689
1997 Tang DC, Ebb D, Hardison RC, Rodgers GP. Restoration of the CCAAT Box or Insertion of the CACCC Motif Activate δ-Globin Gene Expression Blood. 90: 421-427. DOI: 10.1182/Blood.V90.1.421.421_421_427  0.476
1997 Tang DC, Ebb D, Hardison RC, Rodgers GP. Restoration of the CCAAT Box or Insertion of the CACCC Motif Activate δ-Globin Gene Expression Blood. 90: 421-427. DOI: 10.1182/blood.v90.1.421  0.371
1997 Shelton DA, Stegman L, Hardison R, Miller W, Bock JH, Slightom JL, Goodman M, Gumucio DL. Phylogenetic footprinting of hypersensitive site 3 of the β-globin locus control region Blood. 89: 3457-3469. DOI: 10.1182/Blood.V89.9.3457  0.436
1997 Hlnilski L, Miller W, Hardison RC. Role of e boxes in the β-globin locus control region Faseb Journal. 11.  0.313
1996 Jackson JD, Miller W, Hardison RC. Sequences within and flanking hypersensitive sites 3 and 2 of the beta-globin locus control region required for synergistic versus additive interaction with the epsilon-globin gene promoter. Nucleic Acids Research. 24: 4327-35. PMID 8932390 DOI: 10.1093/Nar/24.21.4327  0.647
1996 Jackson JD, Petrykowska H, Philipsen S, Miller W, Hardison R. Role of DNA sequences outside the cores of DNase hypersensitive sites (HSs) in functions of the beta-globin locus control region. Domain opening and synergism between HS2 and HS3. The Journal of Biological Chemistry. 271: 11871-8. PMID 8662652 DOI: 10.1074/Jbc.271.20.11871  0.653
1995 James-Pederson M, Yost S, Shewchuk B, Zeigler T, Miller R, Hardison R.. Flanking and intragenic sequences regulating the expression of the rabbit alpha-globin gene. J. Biol Chem. 3965-73. PMID 7533158 DOI: 10.1074/Jbc.270.8.3965  0.807
1994 Chao KM, Hardison RC, Miller W. Recent developments in linear-space alignment methods: a survey Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 1: 271-291. PMID 8790471 DOI: 10.1089/Cmb.1994.1.271  0.363
1994 Zhang Z, Raghavachari B, Hardison RC, Miller W. Chaining multiple-alignment blocks. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 1: 217-26. PMID 8790466 DOI: 10.1089/Cmb.1994.1.217  0.327
1994 Miller W, Boguski M, Raghavachari B, Zhang Z, Hardison RC. Constructing aligned sequence blocks. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 1: 51-64. PMID 8790453 DOI: 10.1089/Cmb.1994.1.51  0.377
1994 Hardison R, Chao KM, Adamkiewicz M, Price D, Jackson J, Zeigler T, Stojanovic N, Miller W. Positive and negative regulatory elements of the rabbit embryonic epsilon-globin gene revealed by an improved multiple alignment program and functional analysis. Dna Sequence : the Journal of Dna Sequencing and Mapping. 4: 163-76. PMID 8161819 DOI: 10.3109/10425179309015629  0.841
1994 Hardison R, Chao KM, Schwartz S, Stojanovic N, Ganetsky M, Miller W. Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis. Genomics. 21: 344-53. PMID 8088828 DOI: 10.1006/Geno.1994.1275  0.47
1994 Richards CM, Hardison RC, Boyer CD. Expression of the large plastid gene, ORF2280, in tomato fruits and flowers Current Genetics. 26: 494-496. PMID 7874744 DOI: 10.1007/Bf00309939  0.304
1994 Trepicchio WL, Dyer MA, Hardison RC, Baron MH. Upstream regulatory region of the human embryonic beta-like globin gene, epsilon. Dna Sequence : the Journal of Dna Sequencing and Mapping. 4: 409-12. PMID 7841465 DOI: 10.3109/10425179409010191  0.461
1993 Hardison R, Xu J, Jackson J, Mansberger J, Selifonova O, Grotch B, Biesecker J, Petrykowska H, Miller W. Comparative analysis of the locus control region of the rabbit beta-like gene cluster: HS3 increases transient expression of an embryonic epsilon-globin gene. Nucleic Acids Research. 21: 1265-72. PMID 8464710 DOI: 10.1093/Nar/21.5.1265  0.488
1993 Chao KM, Hardison RC, Miller W. Locating well-conserved regions within a pairwise alignment Bioinformatics. 9: 387-396. PMID 8402204 DOI: 10.1093/Bioinformatics/9.4.387  0.427
1993 Hardison R, Miller W. Use of long sequence alignments to study the evolution and regulation of mammalian globin gene clusters. Molecular Biology and Evolution. 10: 73-102. PMID 8383794 DOI: 10.1093/Oxfordjournals.Molbev.A039991  0.448
1993 Yost SE, Shewchuk B, Hardison R. Nuclear protein-binding sites in a transcriptional control region of the rabbit alpha-globin gene. Molecular and Cellular Biology. 13: 5439-49. PMID 8355692 DOI: 10.1128/Mcb.13.9.5439  0.818
1992 Huang X, Miller W, Schwartz S, Hardison RC. Parallelization of a local similarity algorithm Bioinformatics. 8: 155-165. PMID 1591611 DOI: 10.1093/Bioinformatics/8.2.155  0.325
1992 Price DK, Ayres JA, Pasqualone D, Cabell CH, Miller W, Hardison RC. The 5′ ends of LINE1 repeats in rabbit DNA define subfamilies and reveal a short sequence conserved between rabbits and humans Genomics. 14: 320-331. PMID 1427848 DOI: 10.1016/S0888-7543(05)80222-8  0.824
1991 Xu J, Hardison RC. Localization of the α-like globin gene cluster to region q12 of rabbit chromosome 6 by in situ hybridization Genomics. 9: 362-365. PMID 2004787 DOI: 10.1016/0888-7543(91)90265-G  0.305
1991 Krane DE, Clark AG, Cheng JF, Hardison RC. Subfamily relationships and clustering of rabbit C repeats Molecular Biology and Evolution. 8: 1-30. PMID 2002760 DOI: 10.1093/Oxfordjournals.Molbev.A040631  0.801
1991 Hardison R, Krane D, Vandenbergh D, Cheng JF, Mansberger J, Taddie J, Schwartz S, Huang X, Miller W. Sequence and comparative analysis of the rabbit α-like globin gene cluster reveals a rapid mode of evolution in a G + C-rich region of mammalian genomes Journal of Molecular Biology. 222: 233-249. PMID 1960725 DOI: 10.1016/0022-2836(91)90209-O  0.827
1991 Schwartz S, Miller W, Yang Cm, Hardison RC. Software tools for analyzing pairwise alignments of long sequences Nucleic Acids Research. 19: 4663-4667. PMID 1891357 DOI: 10.1093/Nar/19.17.4663  0.441
1991 Vandenbergh DJ, James-Pederson M, Hardison RC. An apparent pause site in the transcription unit of the rabbit alpha-globin gene. Journal of Molecular Biology. 220: 255-70. PMID 1856860 DOI: 10.1016/0022-2836(91)90011-T  0.83
1991 Richards CM, Hinman SB, Boyer CD, Hardison RC. Survey of plastid RNA abundance during tomato fruit ripening: the amounts of RNA from the ORF 2280 region increase in chromoplasts Plant Molecular Biology. 17: 1179-1188. PMID 1718481 DOI: 10.1007/Bf00028734  0.345
1990 Krane DE, Hardison RC. Short interspersed repeats in rabbit DNA can provide functional polyadenylation signals Molecular Biology and Evolution. 7: 1-8. PMID 2299978 DOI: 10.1093/Oxfordjournals.Molbev.A040583  0.789
1990 Huang X, Hardison RC, Miller W. A space-efficient algorithm for local similarities Bioinformatics. 6: 373-381. PMID 2257499 DOI: 10.1093/Bioinformatics/6.4.373  0.347
1990 Lim H, Gounaris I, Hardison RC, Boyer CD. Restriction site and genetic map of Cucurbita pepo chloroplast DNA Current Genetics. 18: 273-275. PMID 2249258 DOI: 10.1007/Bf00318393  0.392
1989 Xu J, Hardison RC. Localization of the β-like globin gene cluster and the genes for parathyroid hormone and c-harvey-ras 1 to region ql4v→q21 of rabbit chromosome 1 by in situ hybridization Cytogenetic and Genome Research. 52: 157-161. PMID 2698321 DOI: 10.1159/000132868  0.359
1989 Hardison RC, Margot JB, Demers GW. Complete nucleotide sequence of the rabbit beta-like globin gene cluster: insights into evolution and regulation Progress in Clinical and Biological Research. 316: 1-17. PMID 2694173  0.824
1989 Kim JH, Yu CY, Bailey A, Hardison R, Shen CK. Unique sequence organization and erythroid cell-specific nuclear factor-binding of mammalian theta 1 globin promoters. Nucleic Acids Research. 17: 5687-700. PMID 2569721 DOI: 10.1093/Nar/17.14.5687  0.531
1989 Margot JB, Demers GW, Hardison RC. Complete nucleotide sequence of the rabbit β-like globin gene cluster. Analysis of intergenic sequences and comparison with the human β-like globin gene cluster Journal of Molecular Biology. 205: 15-40. PMID 2486295 DOI: 10.1016/0022-2836(89)90362-8  0.824
1989 Demers GW, Matunis MJ, Hardison RC. The L1 family of long interspersed repetitive DNA in rabbits: sequence, copy number, conserved open reading frames, and similarity to keratin. Journal of Molecular Evolution. 29: 3-19. PMID 2475641 DOI: 10.1007/Bf02106177  0.769
1988 Cheng JF, Hardison RC. The rabbit α-like globin gene cluster is polymorphic both in the sizes of BamHI fragments and in the numbers of duplicated sets of genes Molecular Biology and Evolution. 5: 486-498. PMID 2904112 DOI: 10.1093/Oxfordjournals.Molbev.A040511  0.612
1988 Cheng JF, Krane DE, Hardison RC. Nucleotide sequence and expression of rabbit globin genes ζ1, ζ2, and ζ3. Pseudogenes generated by block duplications are transcriptionally competent Journal of Biological Chemistry. 263: 9981-9993. PMID 2838486  0.809
1987 Hardison R, Cheng JF, Demers GW, Margot JB. Rabbit alpha-like and beta-like globin gene clusters: comparisons among mammalian globin gene clusters. Progress in Clinical and Biological Research. 251: 91-105. PMID 3432279  0.706
1987 Cheng JF, Raid L, Hardison RC. Block duplications of a zeta-zeta-alpha-theta gene set in the rabbit alpha-like globin gene cluster Journal of Biological Chemistry. 262: 5414-5421. PMID 3031053  0.537
1986 Hardison RC, Sawada I, Cheng JF, Shen CK, Schmid CW. A previously undetected pseudogene in the human alpha globin gene cluster. Nucleic Acids Research. 14: 1903-11. PMID 3952001 DOI: 10.1093/Nar/14.4.1903  0.566
1986 Hardison RC, Gelinas RE. Assignment of orthologous relationships among mammalian α-globin genes by examining flanking regions reveals a rapid rate of evolution Molecular Biology and Evolution. 3: 243-261. PMID 3444401 DOI: 10.1093/Oxfordjournals.Molbev.A040392  0.393
1986 Demers GW, Brech K, Hardison RC. Long interspersed L1 repeats in rabbit DNA are homologous to L1 repeats of rodents and primates in an open-reading-frame region Molecular Biology and Evolution. 3: 179-190. PMID 3444399 DOI: 10.1093/Oxfordjournals.Molbev.A040390  0.76
1986 Jan-Fang Cheng, Raid L, Hardison RC. Isolation and nucleotide sequence of the rabbit globin gene cluster ψζ-α1-ψα. Absence of a pair of α-globin genes evolving in concert Journal of Biological Chemistry. 261: 839-848. PMID 3001084  0.343
1985 Hardison RC, Printz R. Variability within the rabbit C repeats and sequene shared with other SINES Nucleic Acids Research. 13: 1073-1088. PMID 4000935 DOI: 10.1093/Nar/13.4.1073  0.412
1985 Margot JB, Hardison RC. DNase I and nuclease S1 sensitivity of the rabbit β1 globin gene in nuclei and in supercoiled plasmids Journal of Molecular Biology. 184: 195-210. PMID 2993630 DOI: 10.1016/0022-2836(85)90373-0  0.809
1985 Rohrbaugh ML, Johnson JE, James MD, Hardison RC. Transcription unit of the rabbit β1 globin gene Molecular and Cellular Biology. 5: 147-160. PMID 2580228 DOI: 10.1128/Mcb.5.1.147  0.82
1984 Hardison RC, Margot JB. Rabbit globin pseudogene ψβ2 is a hybrid of δ- and β-globin gene sequences Molecular Biology and Evolution. 1: 302-316. PMID 6599969 DOI: 10.1093/Oxfordjournals.Molbev.A040321  0.821
1984 Cheng JF, Printz R, Callaghan T, Shuey D, Hardison RC. The rabbit C family of short, interspersed repeats. Nucleotide sequence determination and transcriptional analysis Journal of Molecular Biology. 176: 1-20. PMID 6204060 DOI: 10.1016/0022-2836(84)90379-6  0.602
1983 Rohrbaugh ML, Hardison RC. Analysis of rabbit β-like globin gene transcripts during development Journal of Molecular Biology. 164: 395-417. PMID 6842597 DOI: 10.1016/0022-2836(83)90058-X  0.79
1981 Hardison RC. The nucleotide sequence of rabbit embryonic globin gene beta 3 Journal of Biological Chemistry. 256: 11780-11786. PMID 6271761  0.339
1979 Hardison RC, Butler ET, Lacy E, Maniatis T, Rosenthal N, Efstratiadis A. The structure and transcription of four linked rabbit beta-like globin genes. Cell. 18: 1285-97. PMID 519769 DOI: 10.1016/0092-8674(79)90239-3  0.568
1979 Lacy E, Hardison RC, Quon D, Maniatis T. The linkage arrangement of four rabbit beta-like globin genes. Cell. 18: 1273-83. PMID 519768 DOI: 10.1016/0092-8674(79)90238-1  0.505
1978 Maniatis T, Hardison RC, Lacy E, Lauer J, O'Connell C, Quon D, Sim GK, Efstratiadis A. The isolation of structural genes from libraries of eucaryotic DNA. Cell. 15: 687-701. PMID 719759 DOI: 10.1016/0092-8674(78)90036-3  0.609
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