Clark D. Wells - Publications

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cell Biology, Molecular Biology, Biochemistry

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wang H, Cai S, Bailey BJ, Reza Saadatzadeh M, Ding J, Tonsing-Carter E, Georgiadis TM, Zachary Gunter T, Long EC, Minto RE, Gordon KR, Sen SE, Cai W, Eitel JA, Waning DL, ... ... Wells CD, et al. Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist. Journal of Neurosurgery. 1-14. PMID 27177180 DOI: 10.3171/2016.1.JNS152513  0.64
2015 He R, Yu ZH, Zhang RY, Wu L, Gunawan AM, Lane BS, Shim JS, Zeng LF, He Y, Chen L, Wells CD, Liu JO, Zhang ZY. Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. Acs Medicinal Chemistry Letters. 6: 782-6. PMID 26191366 DOI: 10.1021/acsmedchemlett.5b00118  0.64
2015 Fournier PG, Juárez P, Jiang G, Clines GA, Niewolna M, Kim HS, Walton HW, Peng XH, Liu Y, Mohammad KS, Wells CD, Chirgwin JM, Guise TA. The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone. Cancer Cell. 27: 809-21. PMID 25982816 DOI: 10.1016/j.ccell.2015.04.009  0.64
2014 Luo N, Conwell MD, Chen X, Kettenhofen CI, Westlake CJ, Cantor LB, Wells CD, Weinreb RN, Corson TW, Spandau DF, Joos KM, Iomini C, Obukhov AG, Sun Y. Primary cilia signaling mediates intraocular pressure sensation. Proceedings of the National Academy of Sciences of the United States of America. 111: 12871-6. PMID 25143588 DOI: 10.1073/pnas.1323292111  0.64
2014 Zeng LF, Zhang RY, Yu ZH, Li S, Wu L, Gunawan AM, Lane BS, Mali RS, Li X, Chan RJ, Kapur R, Wells CD, Zhang ZY. Therapeutic potential of targeting the oncogenic SHP2 phosphatase. Journal of Medicinal Chemistry. 57: 6594-609. PMID 25003231 DOI: 10.1021/jm5006176  0.64
2013 Adler JJ, Johnson DE, Heller BL, Bringman LR, Ranahan WP, Conwell MD, Sun Y, Hudmon A, Wells CD. Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 110: 17368-73. PMID 24101513 DOI: 10.1073/pnas.1308236110  0.64
2013 Adler JJ, Heller BL, Bringman LR, Ranahan WP, Cocklin RR, Goebl MG, Oh M, Lim HS, Ingham RJ, Wells CD. Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth. The Journal of Biological Chemistry. 288: 15181-93. PMID 23564455 DOI: 10.1074/jbc.M112.446534  0.64
2013 Nguyen HB, Babcock JT, Wells CD, Quilliam LA. LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Oncogene. 32: 4100-9. PMID 23027127 DOI: 10.1038/onc.2012.431  0.64
2013 Adler JJ, Judd MV, Bringman LR, Wells CD, Marrs KA. Day as a pathologist: Utilization of technology to guide students in exploring careers in breast cancer pathology American Biology Teacher. 75: 559-565. DOI: 10.1525/abt.2013.75.8.7  0.64
2012 Luo N, West CC, Murga-Zamalloa CA, Sun L, Anderson RM, Wells CD, Weinreb RN, Travers JB, Khanna H, Sun Y. OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome. Human Molecular Genetics. 21: 3333-44. PMID 22543976 DOI: 10.1093/hmg/dds163  0.64
2011 Bai Y, Luo Y, Liu S, Zhang L, Shen K, Dong Y, Walls CD, Quilliam LA, Wells CD, Cao Y, Zhang ZY. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. The Journal of Biological Chemistry. 286: 42316-24. PMID 22009749 DOI: 10.1074/jbc.M111.286302  0.64
2011 Jiang S, Wells CD, Roach PJ. Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1. Biochemical and Biophysical Research Communications. 413: 420-5. PMID 21893048 DOI: 10.1016/j.bbrc.2011.08.106  0.64
2011 Olhovsky M, Williton K, Dai AY, Pasculescu A, Lee JP, Goudreault M, Wells CD, Park JG, Gingras AC, Linding R, Pawson T, Colwill K. OpenFreezer: a reagent information management software system. Nature Methods. 8: 612-3. PMID 21799493 DOI: 10.1038/nmeth.1658  0.64
2011 Ranahan WP, Han Z, Smith-Kinnaman W, Nabinger SC, Heller B, Herbert BS, Chan R, Wells CD. The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases. Cancer Research. 71: 2203-11. PMID 21285250 DOI: 10.1158/0008-5472.CAN-10-1995  0.64
2011 Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism (Journal of Biological Chemistry (2010) 285, (34960-34971)) Journal of Biological Chemistry. 286: 39673. DOI: 10.1074/jbc.A110.150839  0.64
2010 Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism. The Journal of Biological Chemistry. 285: 34960-71. PMID 20810658 DOI: 10.1074/jbc.M110.150839  0.64
2010 Heller B, Adu-Gyamfi E, Smith-Kinnaman W, Babbey C, Vora M, Xue Y, Bittman R, Stahelin RV, Wells CD. Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain. The Journal of Biological Chemistry. 285: 12308-20. PMID 20080965 DOI: 10.1074/jbc.M109.096230  0.64
2009 Meiri D, Greeve MA, Brunet A, Finan D, Wells CD, LaRose J, Rottapel R. Modulation of Rho guanine exchange factor Lfc activity by protein kinase A-mediated phosphorylation. Molecular and Cellular Biology. 29: 5963-73. PMID 19667072 DOI: 10.1128/MCB.01268-08  0.64
2006 Wells CD, Fawcett JP, Traweger A, Yamanaka Y, Goudreault M, Elder K, Kulkarni S, Gish G, Virag C, Lim C, Colwill K, Starostine A, Metalnikov P, Pawson T. A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. Cell. 125: 535-48. PMID 16678097 DOI: 10.1016/j.cell.2006.02.045  0.64
2006 Colwill K, Wells CD, Elder K, Goudreault M, Hersi K, Kulkarni S, Hardy WR, Pawson T, Morin GB. Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites. Bmc Biotechnology. 6: 13. PMID 16519801 DOI: 10.1186/1472-6750-6-13  0.64
2005 Bakal CJ, Finan D, LaRose J, Wells CD, Gish G, Kulkarni S, DeSepulveda P, Wilde A, Rottapel R. The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 9529-34. PMID 15976019 DOI: 10.1073/pnas.0504190102  0.64
2004 Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T. Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Current Biology : Cb. 14: 1436-50. PMID 15324660 DOI: 10.1016/j.cub.2004.07.051  0.64
2003 Chen Z, Singer WD, Wells CD, Sprang SR, Sternweis PC. Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF. The Journal of Biological Chemistry. 278: 9912-9. PMID 12525488 DOI: 10.1074/jbc.M212695200  0.64
2002 Wells CD, Liu MY, Jackson M, Gutowski S, Sternweis PM, Rothstein JD, Kozasa T, Sternweis PC. Mechanisms for reversible regulation between G13 and Rho exchange factors. The Journal of Biological Chemistry. 277: 1174-81. PMID 11698392 DOI: 10.1074/jbc.M105274200  0.64
2001 Chen Z, Wells CD, Sternweis PC, Sprang SR. Structure of the rgRGS domain of p115RhoGEF. Nature Structural Biology. 8: 805-9. PMID 11524686 DOI: 10.1038/nsb0901-805  0.64
2001 Wells CD, Gutowski S, Bollag G, Sternweis PC. Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor. The Journal of Biological Chemistry. 276: 28897-905. PMID 11384980 DOI: 10.1074/jbc.M102913200  0.64
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